Generic_Name	PT	HLT	HLGT	SOC	SUBSET	a	b	c	d	EBGM	EB05	EB95	PRR	PRR_CHISQ	ROR	P_VALUE	BCPNN	logEBGM
Infliximab	Abasia	Gait disturbances	General system disorders NEC	Genrl	1968-2006	57	2527	22445	2981126	1.214	0.973	1.501	1.241	2.58	1.242	0.108	1.49952656	0.19392069
Infliximab	Abdominal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	39	295	22463	2983358	5.899	4.49	7.67	8.031	202.108	8.044	7.242e-46	3.50354798	1.77478285
Infliximab	Abdominal adhesions	Peritoneal and retroperitoneal fibrosis and adhesions	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	20	314	22482	2983339	2.884	1.979	4.09	3.544	33.53	3.546	7.017e-9	2.57393072	1.05917822
Infliximab	Abdominal discomfort	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	16	2545	22486	2981108	0.351	0.231	0.517	0.344	19.97	0.343	7.866e-6	-0.2587373	-1.0469691
Infliximab	Abdominal distension	Flatulence, bloating and distension	Gastrointestinal signs and symptoms	Gastr	1968-2006	71	11241	22431	2972412	0.517	0.424	0.625	0.511	32.944	0.51	9.486e-9	-0.2671418	-0.6597124
Infliximab	Abdominal hernia	Abdominal hernias, site unspecified	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	6	279	22496	2983374	1.177	0.594	2.143	1.372	0.584	1.372	0.445	1.14869133	0.16296883
Infliximab	Abdominal infection	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	4	71	22498	2983582	1.985	0.866	4.038	3.699	7.065	3.699	0.008	1.66821461	0.68561891
Infliximab	Abdominal mass	Abdominal findings abnormal	Gastrointestinal signs and symptoms	Gastr	1968-2006	16	413	22486	2983240	2.368	1.554	3.488	2.84	17.977	2.842	0.00002236	2.00219206	0.86204572
Infliximab	Abdominal neoplasm	Neoplasms unspecified malignancy and site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	7	52	22495	2983601	3.238	1.712	5.713	6.614	28.116	6.617	1.143e-7	2.46142882	1.17495586
Infliximab	Abdominal operation	Abdominal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	3	45	22499	2983608	1.692	0.657	3.743	3.305	4.397	3.306	0.036	1.54627915	0.52591126
Infliximab	Abdominal pain	Gastrointestinal and abdominal pains (excl oral and throat)	Gastrointestinal signs and symptoms	Gastr	1968-2006	433	65576	22069	2918077	1.004	0.927	1.086	1.006	0.014	1.006	0.906	-0.2329188	0.00399202
Infliximab	Abdominal pain lower	Gastrointestinal and abdominal pains (excl oral and throat)	Gastrointestinal signs and symptoms	Gastr	1968-2006	29	2038	22473	2981615	0.952	0.697	1.276	0.97	0.026	0.97	0.872	0.85311007	-0.0491902
Infliximab	Abdominal pain upper	Gastrointestinal and abdominal pains (excl oral and throat)	Gastrointestinal signs and symptoms	Gastr	1968-2006	113	14645	22389	2969008	0.532	0.455	0.62	0.527	47.873	0.525	4.547e-12	0.01446424	-0.6311118
Infliximab	Abdominal rigidity	Abdominal findings abnormal	Gastrointestinal signs and symptoms	Gastr	1968-2006	4	256	22498	2983397	0.833	0.364	1.692	0.93	0.021	0.93	0.885	0.75211903	-0.1827216
Infliximab	Abdominal sepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	3	46	22499	2983607	1.751	0.68	3.876	3.642	5.066	3.642	0.024	1.53835591	0.56018705
Infliximab	Abdominal strangulated hernia	Abdominal hernias, site unspecified	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	8	91	22494	2983562	3.037	1.674	5.17	5.361	23.969	5.362	9.791e-7	2.3590855	1.11087019
Infliximab	Abdominal symptom	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	3	136	22499	2983517	1.221	0.475	2.7	1.724	0.891	1.725	0.345	0.96020139	0.1996702
Infliximab	Abdominal tenderness	Gastrointestinal and abdominal pains (excl oral and throat)	Gastrointestinal signs and symptoms	Gastr	1968-2006	16	1055	22486	2982598	1.084	0.711	1.596	1.137	0.258	1.137	0.612	0.90350325	0.0806579
Infliximab	Abdominal wall abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	5	46	22497	2983607	2.672	1.265	5.129	5.853	17.449	5.855	0.00002952	2.10760152	0.98282726
Infliximab	Abdominal wall cyst	Abdominal wall conditions NEC	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	2	12	22500	2983641	1.933	0.622	4.91	13.41	16.134	13.41	0.00005901	1.43033808	0.6590732
Infliximab	Abdominal wall infection	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	9	22501	2983644	1.184	0.273	3.707	6.537	3.89	6.539	0.049	0.88501574	0.16889854
Infliximab	Abnormal behaviour	Abnormal behaviour NEC	Psychiatric and behavioural symptoms NEC	Psych	1968-2006	19	7064	22483	2976589	0.17	0.116	0.243	0.164	81.16	0.163	2.081e-19	-1.4477102	-1.7719568
Infliximab	Abnormal dreams	Parasomnias	Sleep disorders and disturbances	Psych	1968-2006	2	8836	22500	2974817	0.053	0.017	0.133	0.043	43.17	0.043	5.017e-11	-4.499581	-2.9374634
Infliximab	Abnormal faeces	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	6	2620	22496	2981033	0.405	0.204	0.737	0.396	5.474	0.396	0.019	-1.5732694	-0.9038682
Infliximab	Abortion	Abortions not specified as induced or spontaneous	Abortions and stillbirth	Preg	1968-2006	3	3213	22499	2980440	0.423	0.164	0.934	0.41	2.496	0.41	0.114	-2.6604414	-0.8603831
Infliximab	Abortion early	Abortions not specified as induced or spontaneous	Abortions and stillbirth	Preg	1968-2006	1	6	22501	2983647	1.2	0.277	3.76	7.769	4.502	7.769	0.034	0.91547736	0.18232156
Infliximab	Abortion induced	Induced abortions	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	21	2522	22481	2981131	0.471	0.326	0.662	0.464	12.835	0.464	0.0003401	0.12291205	-0.7528972
Infliximab	Abortion spontaneous	Abortions spontaneous	Abortions and stillbirth	Preg	1968-2006	92	4899	22410	2978754	1.067	0.896	1.262	1.077	0.495	1.078	0.482	1.26444872	0.06485097
Infliximab	Abortion threatened	Abortions spontaneous	Abortions and stillbirth	Preg	1968-2006	1	111	22501	2983542	0.514	0.119	1.606	0.542	0.391	0.542	0.532	0.11069173	-0.665532
Infliximab	Abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	167	2504	22335	2981149	6.425	5.645	7.291	7.73	825.821	7.791	0	2.98840966	1.86019663
Infliximab	Abscess bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	22	22501	2983631	1.086	0.251	3.395	3.619	1.76	3.619	0.185	0.75997701	0.08250122
Infliximab	Abscess drainage	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	3	108	22499	2983545	1.537	0.597	3.4	2.644	2.901	2.644	0.089	1.11657892	0.42983246
Infliximab	Abscess intestinal	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	25	136	22477	2983517	7.669	5.196	11.629	12.321	205.028	12.334	0	3.54866261	2.03718623
Infliximab	Abscess limb	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	18	141	22484	2983512	4.84	3.239	7.056	7.61	86.764	7.616	1.223e-20	3.1059773	1.57691472
Infliximab	Abscess neck	Muscle and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	29	22501	2983624	1.005	0.233	3.14	2.595	0.904	2.595	0.342	0.69688322	0.00498754
Infliximab	Abscess oral	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	80	22501	2983573	0.71	0.164	2.215	0.971	0.001	0.971	0.977	0.30537124	-0.3424903
Infliximab	Abscess soft tissue	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	3	21	22499	2983632	2.187	0.847	4.866	7.032	12.751	7.032	0.0003558	1.75079308	0.78253074
Infliximab	Abscess sweat gland	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	2	1	22500	2983652	2.774	0.748	26.64	389.235	170.989	389.235	4.5e-39	1.54208236	1.02029032
Infliximab	Acanthosis	Skin hyperplasias and hypertrophies	Cornification and dystrophic skin disorders	Skin	1968-2006	2	57	22500	2983596	1.323	0.429	3.319	2.67	1.898	2.67	0.168	1.04639056	0.27990189
Infliximab	Acarodermatitis	Ectoparasitic infestations	Ectoparasitic disorders	Infec	1968-2006	1	77	22501	2983576	0.719	0.166	2.243	0.997	0	0.997	0.998	0.3256836	-0.3298939
Infliximab	Accelerated hypertension	Accelerated and malignant hypertension	Vascular hypertensive disorders	Vasc	1968-2006	4	83	22498	2983570	1.979	0.864	4.026	3.656	6.996	3.656	0.008	1.58751343	0.68259167
Infliximab	Accident	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	9	5915	22493	2977738	0.401	0.229	0.662	0.392	8.372	0.391	0.004	-2.1945802	-0.9137939
Infliximab	Accident at work	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	138	22501	2983515	0.452	0.105	1.412	0.441	0.703	0.441	0.402	-0.0397991	-0.7940731
Infliximab	Accidental exposure	Medication errors due to accidental exposures	Medication errors	Inj&P	1968-2006	7	1979	22495	2981674	0.232	0.123	0.407	0.221	19.209	0.22	0.00001172	-0.9996463	-1.4610179
Infliximab	Accidental overdose	Overdoses	Medication errors	Inj&P	1968-2006	2	11736	22500	2971917	0.028	0.009	0.071	0.022	85.588	0.022	2.216e-20	-4.9050655	-3.5755508
Infliximab	Accommodation disorder	Refractive and accommodative disorders	Vision disorders	Eye	1968-2006	3	697	22499	2982956	0.708	0.275	1.566	0.778	0.187	0.778	0.666	-0.6526563	-0.3453112
Infliximab	Acetabulum fracture	Pelvic fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	1	34	22501	2983619	0.874	0.202	2.728	1.618	0.225	1.618	0.635	0.65344776	-0.1346749
Infliximab	Acetonaemic vomiting	Nausea and vomiting symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	0	22501	2983653	1.397	0.317	4.464	1095.931	146.141	1103.636	1.209e-33	0.97840063	0.33432708
Infliximab	Acid fast bacilli infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	8	32	22494	2983621	4.925	2.585	10.002	13.903	72.654	13.913	1.545e-17	2.78120756	1.59432427
Infliximab	Acid fast stain positive	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	6	44	22496	2983609	3.764	1.867	7.165	11.65	43.977	11.654	3.323e-11	2.33783125	1.32548222
Infliximab	Acidosis	Mixed acid-base disorders	Acid-base disorders	Metab	1968-2006	18	3546	22484	2980107	0.677	0.455	0.977	0.682	2.629	0.682	0.105	-0.5552758	-0.390084
Infliximab	Acinetobacter infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	12	120	22490	2983533	3.392	2.084	5.287	5.139	35.189	5.141	2.992e-9	2.69817774	1.22141972
Infliximab	Acne	Acnes	Skin appendage conditions	Skin	1968-2006	13	6734	22489	2976919	0.418	0.262	0.64	0.412	10.866	0.412	0.001	-1.8933385	-0.8722738
Infliximab	Acne conglobata	Acnes	Skin appendage conditions	Skin	1968-2006	1	8	22501	2983645	1.272	0.293	3.997	15.239	9.007	15.239	0.003	0.89509832	0.24059046
Infliximab	Acoustic neuroma	Neuromas	Nervous system neoplasms benign	Neopl	1968-2006	3	43	22499	2983610	1.795	0.697	3.974	3.721	5.612	3.721	0.018	1.56225739	0.58500502
Infliximab	Acquired diaphragmatic eventration	Diaphragmatic disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	2	56	22500	2983597	1.247	0.404	3.128	2.277	1.356	2.278	0.244	1.05390137	0.22074067
Infliximab	Acquired haemophilia	Coagulation factor deficiencies	Coagulopathies and bleeding diatheses (excl thrombocytopenic)	Blood	1968-2006	1	15	22501	2983638	1.144	0.264	3.58	4.902	2.797	4.902	0.094	0.82595649	0.13453089
Infliximab	Acquired oesophageal web	Oesophageal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	3	32	22499	2983621	2.068	0.802	4.59	5.446	10.024	5.447	0.002	1.65344797	0.72658196
Infliximab	Acrochordon	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	3	86	22499	2983567	1.559	0.606	3.448	2.721	3.09	2.721	0.079	1.2525631	0.44404459
Infliximab	Acrodermatitis	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	1	12	22501	2983641	1.174	0.271	3.675	5.492	3.573	5.492	0.059	0.85518395	0.16041672
Infliximab	Actinic keratosis	Skin preneoplastic conditions NEC	Cornification and dystrophic skin disorders	Skin	1968-2006	8	155	22494	2983498	2.585	1.426	4.393	3.906	15.813	3.907	0.00006993	2.00838109	0.94972551
Infliximab	Actinomycosis	Actinomycotic infectious disorders	Bacterial infectious disorders	Infec	1968-2006	3	188	22499	2983465	1.053	0.409	2.329	1.366	0.281	1.366	0.596	0.70829485	0.05164323
Infliximab	Actinomycotic pulmonary infection	Actinomycotic infectious disorders	Bacterial infectious disorders	Infec	1968-2006	2	9	22500	2983644	2.032	0.65	5.213	18.901	23.465	18.904	1.272e-6	1.45996566	0.70902053
Infliximab	Activated partial thromboplastin time	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	62	22501	2983591	0.627	0.145	1.957	0.759	0.075	0.759	0.784	0.43176963	-0.4668087
Infliximab	Activated partial thromboplastin time prolonged	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	7	2632	22495	2981021	0.194	0.103	0.34	0.184	25.414	0.184	4.625e-7	-1.3874105	-1.6398971
Infliximab	Activated partial thromboplastin time shortened	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	184	22499	2983469	0.958	0.372	2.117	1.181	0.081	1.181	0.775	0.72618562	-0.0429075
Infliximab	Activities of daily living impaired	Disability issues	Lifestyle issues	SocCi	1968-2006	11	1353	22491	2982300	0.439	0.264	0.695	0.432	8.122	0.432	0.004	0.08675983	-0.8232559
Infliximab	Acute abdomen	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	7	572	22495	2983081	1.148	0.609	2.012	1.3	0.471	1.301	0.492	0.57366799	0.1380213
Infliximab	Acute coronary syndrome	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	18	739	22484	2982914	1.536	1.033	2.216	1.677	4.669	1.677	0.031	1.499827	0.42918163
Infliximab	Acute endocarditis	Cardiac infections	Infections - pathogen class unspecified	Infec	1968-2006	1	12	22501	2983641	1.145	0.265	3.584	4.967	2.832	4.968	0.092	0.85518395	0.13540464
Infliximab	Acute febrile neutrophilic dermatosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	14	194	22488	2983459	3.09	1.969	4.667	4.192	30.959	4.195	2.635e-8	2.54153447	1.12817109
Infliximab	Acute generalised exanthematous pustulosis	Pustular conditions	Epidermal and dermal conditions	Skin	1968-2006	2	335	22500	2983318	0.376	0.122	0.942	0.352	2.33	0.352	0.127	-0.2426584	-0.9781661
Infliximab	Acute graft versus host disease	Transplant rejections	Immune disorders NEC	Immun	1968-2006	1	0	22501	2983653	1.393	0.316	4.449	1094.868	133.397	1102.573	7.402e-31	0.97840063	0.33145969
Infliximab	Acute left ventricular failure	Left ventricular failures	Heart failures	Card	1968-2006	2	30	22500	2983623	1.647	0.533	4.143	5.322	6.081	5.323	0.014	1.26431441	0.49895545
Infliximab	Acute leukaemia	Leukaemias acute NEC	Leukaemias	Neopl	1968-2006	11	467	22491	2983186	2.192	1.319	3.471	2.76	11.646	2.761	0.001	1.37918643	0.78481437
Infliximab	Acute lymphocytic leukaemia	Leukaemias acute lymphocytic	Leukaemias	Neopl	1968-2006	5	375	22497	2983278	1.065	0.505	2.034	1.239	0.225	1.239	0.635	0.63117682	0.0629748
Infliximab	Acute megakaryocytic leukaemia	Leukaemias acute myeloid	Leukaemias	Neopl	1968-2006	2	13	22500	2983640	1.858	0.599	4.7	9.509	12.375	9.512	0.0004351	1.4205959	0.61950064
Infliximab	Acute myeloid leukaemia	Leukaemias acute myeloid	Leukaemias	Neopl	1968-2006	34	1671	22468	2981982	1.584	1.188	2.078	1.669	8.817	1.67	0.003	1.33496963	0.45995329
Infliximab	Acute myeloid leukaemia recurrent	Leukaemias acute myeloid	Leukaemias	Neopl	1968-2006	1	38	22501	2983615	0.928	0.215	2.898	1.911	0.431	1.911	0.511	0.61961696	-0.0747235
Infliximab	Acute myelomonocytic leukaemia	Leukaemias acute myeloid	Leukaemias	Neopl	1968-2006	4	82	22498	2983571	2.458	1.07	5.02	6.033	14.93	6.034	0.0001116	1.59406879	0.89934801
Infliximab	Acute myocardial infarction	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	68	3983	22434	2979670	1.088	0.889	1.322	1.103	0.635	1.103	0.426	1.12660803	0.08434115
Infliximab	Acute phase reaction	Inflammations	General system disorders NEC	Genrl	1968-2006	1	8	22501	2983645	1.164	0.269	3.642	5.474	3.3	5.474	0.069	0.89509832	0.15186235
Infliximab	Acute prerenal failure	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	5	379	22497	2983274	0.852	0.404	1.626	0.933	0.023	0.933	0.879	0.61998237	-0.1601688
Infliximab	Acute promyelocytic leukaemia	Leukaemias acute myeloid	Leukaemias	Neopl	1968-2006	1	180	22501	2983473	0.422	0.097	1.316	0.396	0.906	0.396	0.341	-0.2465559	-0.86275
Infliximab	Acute pulmonary histoplasmosis	Histoplasma infections	Fungal infectious disorders	Infec	1968-2006	16	4	22486	2983649	31.08	20.117	46.312	179.636	532.264	179.867	0	3.87534915	3.43656453
Infliximab	Acute pulmonary oedema	Pulmonary oedemas	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	14	769	22488	2982884	0.903	0.576	1.363	0.936	0.06	0.936	0.806	1.11726099	-0.1020327
Infliximab	Acute respiratory distress syndrome	Pulmonary oedemas	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	162	4093	22340	2979560	2.833	2.486	3.217	3.014	204.226	3.031	0	2.29808601	1.04133622
Infliximab	Acute respiratory failure	Respiratory failures (excl neonatal)	Respiratory disorders NEC	Resp	1968-2006	44	891	22458	2982762	2.442	1.897	3.104	2.683	43.323	2.688	4.642e-11	2.48080401	0.89281738
Infliximab	Acute sinusitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	6	224	22496	2983429	1.656	0.836	3.016	2.165	3.663	2.166	0.056	1.3519404	0.50440506
Infliximab	Acute tonsillitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	2	46	22500	2983607	1.341	0.435	3.365	2.701	2.046	2.701	0.153	1.13124153	0.2934156
Infliximab	Adenocarcinoma	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	37	409	22465	2983244	4.904	3.717	6.38	6.267	144.784	6.277	2.394e-33	3.11970799	1.5900512
Infliximab	Adenocarcinoma of the cervix	Cervix neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	20	22500	2983633	1.909	0.615	4.844	11.066	14.823	11.067	0.0001181	1.3541825	0.64657954
Infliximab	Adenocarcinoma pancreas	Pancreatic neoplasms malignant (excl islet cell and carcinoid)	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	4	40	22498	2983613	2.457	1.07	5.019	6.064	14.899	6.065	0.0001134	1.90034276	0.89894109
Infliximab	Adenoma benign	Neoplasms benign site unspecified NEC	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	2	387	22500	2983266	0.727	0.236	1.823	0.852	0.05	0.852	0.823	-0.3938908	-0.3188288
Infliximab	Adenomyosis	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	2	56	22500	2983597	1.126	0.365	2.823	1.826	0.707	1.826	0.4	1.05390137	0.11867153
Infliximab	Adenovirus infection	Adenoviral infections	Viral infectious disorders	Infec	1968-2006	1	139	22501	2983514	0.429	0.099	1.339	0.406	0.856	0.406	0.355	-0.0450823	-0.8462984
Infliximab	Adhesiolysis	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	12	22501	2983641	1.127	0.261	3.526	4.306	2.452	4.306	0.117	0.85518395	0.11955924
Infliximab	Adhesion	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	7	166	22495	2983487	1.928	1.022	3.379	2.63	6.53	2.631	0.011	1.79061117	0.6564832
Infliximab	Adnexa uteri mass	Pelvis and broad ligament disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	3	34	22499	2983619	2.038	0.79	4.521	5.474	9.419	5.474	0.002	1.63643342	0.71196893
Infliximab	Adnexa uteri pain	Pelvis and broad ligament disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	72	22501	2983581	0.656	0.152	2.046	0.826	0.036	0.826	0.85	0.36018617	-0.4215945
Infliximab	Adrenal adenoma	Adrenal neoplasms benign	Endocrine neoplasms benign	Neopl	1968-2006	2	72	22500	2983581	1.092	0.354	2.739	1.712	0.567	1.712	0.451	0.93818202	0.08801088
Infliximab	Adrenal cortex atrophy	Adrenal cortical hypofunctions	Adrenal gland disorders	Endo	1968-2006	1	22	22501	2983631	1.274	0.294	4.006	15.463	9.288	15.467	0.002	0.75997701	0.24216156
Infliximab	Adrenal cortex necrosis	Adrenal gland disorders NEC	Adrenal gland disorders	Endo	1968-2006	1	20	22501	2983633	1.086	0.251	3.394	3.637	1.757	3.638	0.185	0.77852244	0.08250122
Infliximab	Adrenal disorder	Adrenal gland disorders NEC	Adrenal gland disorders	Endo	1968-2006	4	219	22498	2983434	1.135	0.495	2.306	1.418	0.467	1.418	0.494	0.8945622	0.12663265
Infliximab	Adrenal gland tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.279	0.295	4.021	19.727	9.868	19.727	0.002	0.95711984	0.24607852
Infliximab	Adrenal haemorrhage	Adrenal gland disorders NEC	Adrenal gland disorders	Endo	1968-2006	1	99	22501	2983554	0.727	0.168	2.269	1.022	0	1.022	0.982	0.18296925	-0.3188288
Infliximab	Adrenal insufficiency	Adrenal cortical hypofunctions	Adrenal gland disorders	Endo	1968-2006	30	846	22472	2982807	3.153	2.32	4.207	3.703	54.863	3.707	1.292e-13	2.02510821	1.14835438
Infliximab	Adrenal mass	Adrenal gland disorders NEC	Adrenal gland disorders	Endo	1968-2006	1	61	22501	2983592	0.754	0.174	2.354	1.109	0.011	1.109	0.918	0.43912725	-0.2823629
Infliximab	Adrenal neoplasm	Endocrine neoplasms malignant and unspecified NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	3	82	22499	2983571	1.478	0.574	3.268	2.459	2.44	2.459	0.118	1.27872578	0.39068982
Infliximab	Adrenal suppression	Adrenal cortical hypofunctions	Adrenal gland disorders	Endo	1968-2006	3	131	22499	2983522	1.162	0.451	2.568	1.595	0.639	1.596	0.424	0.98691172	0.15014266
Infliximab	Adrenocortical insufficiency acute	Adrenal cortical hypofunctions	Adrenal gland disorders	Endo	1968-2006	5	200	22497	2983453	1.718	0.815	3.283	2.456	4.124	2.456	0.042	1.23233133	0.54116082
Infliximab	Adrenocortical insufficiency chronic				1968-2006	5	84	22497	2983569	2.217	1.051	4.24	3.912	9.773	3.913	0.002	1.83752599	0.79615493
Infliximab	Adverse drug reaction	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	13	773	22489	2982880	0.869	0.545	1.331	0.899	0.142	0.899	0.706	1.01300925	-0.1404122
Infliximab	Adverse event	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	12	4592	22490	2979061	0.121	0.074	0.188	0.115	83.572	0.113	6.144e-20	-1.4608376	-2.1119647
Infliximab	Affect lability	Affect alterations NEC	Mood disorders and disturbances NEC	Psych	1968-2006	3	754	22499	2982899	0.217	0.084	0.479	0.197	9.917	0.196	0.002	-0.7481067	-1.5278579
Infliximab	Affective disorder	Mood disorders NEC	Mood disorders and disturbances NEC	Psych	1968-2006	2	508	22500	2983145	0.278	0.09	0.698	0.249	4.501	0.249	0.034	-0.6944089	-1.2801342
Infliximab	Ageusia	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	6	4211	22496	2979442	0.197	0.1	0.359	0.185	21.477	0.185	3.581e-6	-2.2307957	-1.6245516
Infliximab	Aggression	Behaviour and socialisation disturbances	Personality disorders and disturbances in behaviour	Psych	1968-2006	6	8065	22496	2975588	0.05	0.025	0.091	0.045	121.298	0.045	3.289e-28	-3.1478824	-2.9957323
Infliximab	Agitation	Anxiety symptoms	Anxiety disorders and symptoms	Psych	1968-2006	27	24140	22475	2959513	0.147	0.106	0.198	0.142	140.813	0.141	1.768e-32	-2.722185	-1.9173227
Infliximab	Agranulocytosis	Neutropenias	White blood cell disorders	Blood	1968-2006	21	7350	22481	2976303	0.532	0.369	0.749	0.53	8.717	0.529	0.003	-1.3668013	-0.6311118
Infliximab	Akathisia	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	2618	22501	2981035	0.093	0.021	0.292	0.065	13.427	0.065	0.000248	-3.376959	-2.3751558
Infliximab	Akinesia	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	9	807	22493	2982846	1.074	0.613	1.775	1.168	0.212	1.168	0.645	0.48125257	0.07139
Infliximab	Alanine aminotransferase	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	8	198	22494	2983455	1.36	0.751	2.309	1.577	1.637	1.579	0.201	1.81303969	0.3074847
Infliximab	Alanine aminotransferase abnormal	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	3	163	22499	2983490	0.768	0.298	1.698	0.865	0.061	0.865	0.806	0.82393405	-0.2639655
Infliximab	Alanine aminotransferase decreased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	97	22501	2983556	0.533	0.123	1.663	0.569	0.32	0.569	0.572	0.19537549	-0.6292339
Infliximab	Alanine aminotransferase increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	180	23045	22322	2960608	0.712	0.629	0.803	0.708	21.581	0.705	3.393e-6	0.0278774	-0.3396774
Infliximab	Albumin globulin ratio abnormal	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	1	33	22501	2983620	1.228	0.283	3.85	8.862	5.731	8.864	0.017	0.66203088	0.20538683
Infliximab	Albumin urine present	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	255	22501	2983398	0.542	0.125	1.693	0.584	0.283	0.584	0.595	-0.5550714	-0.6124893
Infliximab	Albuminuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	3	2104	22499	2981549	1.383	0.537	3.057	2.158	1.778	2.158	0.182	-2.0797999	0.32425505
Infliximab	Alcohol detoxification	Drug withdrawal therapies	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	8	22501	2983645	1.223	0.282	3.835	8.831	5.492	8.831	0.019	0.89509832	0.20130686
Infliximab	Alcohol poisoning	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	1	533	22501	2983120	0.161	0.037	0.503	0.119	6.54	0.119	0.011	-1.3322034	-1.8263509
Infliximab	Alcohol use	Alcohol product use	Lifestyle issues	SocCi	1968-2006	5	1104	22497	2982549	0.282	0.134	0.539	0.268	9.962	0.267	0.002	-0.6438282	-1.2658482
Infliximab	Alcoholic liver disease	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	3	77	22499	2983576	1.54	0.598	3.407	2.61	2.933	2.61	0.087	1.31211067	0.43178242
Infliximab	Alcoholism	Substance-related disorders	Psychiatric disorders NEC	Psych	1968-2006	3	716	22499	2982937	0.291	0.113	0.642	0.27	5.89	0.27	0.015	-0.6851794	-1.234432
Infliximab	Aldolase increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	2	194	22500	2983459	0.695	0.225	1.742	0.798	0.102	0.798	0.75	0.27120108	-0.3638434
Infliximab	Alkalosis	Metabolic alkaloses	Acid-base disorders	Metab	1968-2006	2	304	22500	2983349	0.936	0.303	2.347	1.286	0.12	1.286	0.729	-0.1443324	-0.0661398
Infliximab	Allergic granulomatous angiitis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	5	761	22497	2982892	0.447	0.212	0.854	0.443	3.498	0.443	0.061	-0.1776538	-0.8051967
Infliximab	Allergic keratitis	Corneal infections, oedemas and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	2	1	22500	2983652	2.641	0.739	18.904	203.227	134.159	203.894	5.043e-31	1.54208236	0.97115763
Infliximab	Allergy to arthropod bite	Allergic conditions NEC	Allergic conditions	Immun	1968-2006	1	5	22501	2983648	1.247	0.288	3.913	11.164	6.93	11.164	0.008	0.92577585	0.22074067
Infliximab	Allergy to chemicals	Allergies to foods, food additives, drugs and other chemicals	Allergic conditions	Immun	1968-2006	1	34	22501	2983619	0.825	0.191	2.576	1.379	0.102	1.379	0.749	0.65344776	-0.1923719
Infliximab	Allodynia	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	1	36	22501	2983617	0.85	0.197	2.654	1.498	0.158	1.498	0.691	0.63643321	-0.1625189
Infliximab	Alopecia	Alopecias	Skin appendage conditions	Skin	1968-2006	91	42328	22411	2941325	0.59	0.495	0.698	0.585	26.637	0.583	2.455e-7	-1.8231271	-0.5276327
Infliximab	Alopecia areata	Alopecias	Skin appendage conditions	Skin	1968-2006	4	52	22498	2983601	2.276	0.992	4.639	4.927	11.407	4.928	0.001	1.8060072	0.82241952
Infliximab	Alopecia effluvium	Alopecias	Skin appendage conditions	Skin	1968-2006	1	38	22501	2983615	0.875	0.202	2.732	1.636	0.23	1.636	0.632	0.61961696	-0.1335314
Infliximab	Alopecia totalis	Alopecias	Skin appendage conditions	Skin	1968-2006	1	35	22501	2983618	0.817	0.189	2.55	1.338	0.086	1.338	0.769	0.64491541	-0.2021162
Infliximab	Alpha 1 foetoprotein increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	3	183	22499	2983470	0.97	0.377	2.144	1.202	0.1	1.202	0.752	0.73069318	-0.0304592
Infliximab	Alpha 1 globulin increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	1	36	22501	2983617	0.913	0.211	2.85	1.846	0.366	1.846	0.545	0.63643321	-0.0910194
Infliximab	Alpha haemolytic streptococcal infection	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	4	146	22498	2983507	1.225	0.535	2.489	1.575	0.819	1.575	0.366	1.2250515	0.20294084
Infliximab	Alpha tumour necrosis factor increased	Immune response protein analyses NEC	Immunology and allergy investigations	Inv	1968-2006	1	13	22501	2983640	1.081	0.25	3.378	3.626	1.697	3.626	0.193	0.84537553	0.07788654
Infliximab	Alpha-1 anti-trypsin increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	1	14	22501	2983639	1.121	0.259	3.506	4.148	2.324	4.148	0.127	0.83563334	0.11422114
Infliximab	Alveolitis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	28	434	22474	2983219	3.653	2.658	4.922	4.512	69.373	4.516	8.152e-17	2.69046398	1.29554875
Infliximab	Alveolitis allergic	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	12	340	22490	2983313	2.013	1.238	3.131	2.416	9.556	2.417	0.002	1.82754756	0.69962615
Infliximab	Alveolitis fibrosing	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	23	112	22479	2983541	8.491	5.468	13.423	13.561	212.929	13.578	0	3.56649735	2.13900678
Infliximab	Amaurosis	Blindness (excl colour blindness)	Vision disorders	Eye	1968-2006	3	40	22499	2983613	1.895	0.736	4.199	4.275	6.997	4.275	0.008	1.58656148	0.63921884
Infliximab	Amaurosis fugax	Blindness (excl colour blindness)	Vision disorders	Eye	1968-2006	3	179	22499	2983474	0.975	0.379	2.156	1.214	0.11	1.214	0.741	0.74886559	-0.0253178
Infliximab	Amenorrhoea	Menstruation with decreased bleeding	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	1	7419	22501	2976234	0.045	0.01	0.141	0.03	31.092	0.03	2.46e-8	-4.8356554	-3.1010928
Infliximab	Ammonia	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	2	12	22500	2983641	1.754	0.567	4.421	6.894	8.738	6.897	0.003	1.43033808	0.56189889
Infliximab	Ammonia increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	988	22501	2982665	0.099	0.023	0.31	0.068	12.51	0.068	0.0004047	-2.0822158	-2.3126354
Infliximab	Amnesia	Memory loss (excl dementia)	Mental impairment disorders	Nerv	1968-2006	55	17615	22447	2966038	0.483	0.385	0.599	0.477	31.253	0.476	2.265e-8	-1.2701848	-0.7277386
Infliximab	Amniotic cavity disorder	Amniotic fluid and cavity disorders of pregnancy NEC	Placental, amniotic and cavity disorders (excl haemorrhages)	Preg	1968-2006	1	43	22501	2983610	0.814	0.188	2.541	1.34	0.081	1.34	0.776	0.5784143	-0.2057949
Infliximab	Amniotic fluid volume decreased	Foetal and neonatal diagnostic procedures	Foetal and neonatal investigations	Inv	1968-2006	2	42	22500	2983611	1.254	0.407	3.146	2.354	1.414	2.355	0.234	1.16337692	0.22633844
Infliximab	Amoebiasis	Amoebic infections	Protozoal infectious disorders	Infec	1968-2006	1	20	22501	2983633	1.168	0.27	3.657	5.658	3.392	5.658	0.066	0.77852244	0.15529288
Infliximab	Amphetamines positive	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	1	37	22501	2983616	0.848	0.196	2.648	1.487	0.154	1.487	0.695	0.62800058	-0.1648746
Infliximab	Amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	4	158	22498	2983495	1.281	0.559	2.602	1.682	1.079	1.683	0.299	1.165256	0.24764102
Infliximab	Amyloidosis	Amyloidoses	Immune disorders NEC	Immun	1968-2006	15	213	22487	2983440	4.23	2.731	6.34	6.738	61.405	6.741	4.647e-15	2.55254683	1.44220199
Infliximab	Amyotrophic lateral sclerosis	Motor neurone diseases	Neuromuscular disorders	Nerv	1968-2006	22	289	22480	2983364	4.08	2.847	5.706	5.448	71.612	5.452	2.619e-17	2.77795467	1.40609699
Infliximab	Amyotrophy	Myopathies	Muscle disorders	Musc	1968-2006	3	156	22499	2983497	1.08	0.419	2.387	1.421	0.356	1.421	0.551	0.85804582	0.07696104
Infliximab	Anaemia	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	334	29191	22168	2954462	1.133	1.035	1.239	1.14	5.643	1.142	0.018	0.56855378	0.12486898
Infliximab	Anaemia haemolytic autoimmune	Anaemias haemolytic immune	Haemolyses and related conditions	Blood	1968-2006	1	500	22501	2983153	0.187	0.043	0.585	0.139	5.238	0.139	0.022	-1.2590505	-1.6766467
Infliximab	Anaemia macrocytic	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	6	836	22496	2982817	0.606	0.306	1.103	0.617	1.395	0.616	0.238	-0.0723044	-0.5008753
Infliximab	Anaemia megaloblastic	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	1	325	22501	2983328	0.587	0.136	1.831	0.674	0.157	0.674	0.692	-0.793493	-0.5327305
Infliximab	Anaemia of chronic disease	Anaemias due to chronic disorders	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	13	93	22489	2983560	5.088	3.139	8.11	10.091	82.296	10.098	1.172e-19	2.95373549	1.62688483
Infliximab	Anaemia vitamin B12 deficiency	Anaemia deficiencies	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	1	111	22501	2983542	0.9	0.208	2.811	1.741	0.315	1.741	0.575	0.11069173	-0.1053605
Infliximab	Anaesthetic complication neurological	Anaesthetic complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	72	22501	2983581	0.681	0.158	2.127	0.893	0.013	0.893	0.911	0.36018617	-0.384193
Infliximab	Anaesthetic complication pulmonary	Anaesthetic complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	19	22501	2983634	1.005	0.232	3.138	2.625	0.907	2.626	0.341	0.78788532	0.00498754
Infliximab	Anal cancer	Anal canal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	21	43	22481	2983610	19.265	13.038	27.449	35.607	399.07	35.65	0	3.88388415	2.95828998
Infliximab	Anal discomfort	Anal and rectal disorders NEC	Anal and rectal conditions NEC	Gastr	1968-2006	1	115	22501	2983538	0.452	0.105	1.412	0.439	0.705	0.439	0.401	0.08738197	-0.7940731
Infliximab	Anal fissure	Anal and rectal disorders NEC	Anal and rectal conditions NEC	Gastr	1968-2006	6	270	22496	2983383	1.153	0.582	2.1	1.337	0.491	1.337	0.484	1.18005262	0.14236724
Infliximab	Anal fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	44	119	22458	2983534	15.212	11.643	19.476	24.934	618.291	24.992	0	4.33031881	2.72208459
Infliximab	Anal haemorrhage	Intestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	3	106	22499	2983547	1.086	0.422	2.4	1.432	0.376	1.432	0.54	1.12842497	0.08250122
Infliximab	Anal neoplasm	Colorectal and anal neoplasms malignancy unspecified	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	9	22501	2983644	1.231	0.284	3.861	8.139	5.958	8.139	0.015	0.88501574	0.20782685
Infliximab	Anal stenosis	Anal and rectal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	5	23	22497	2983630	3.275	1.536	6.419	10.318	33.166	10.319	8.463e-9	2.2995931	1.18631787
Infliximab	Anal ulcer	Anal and rectal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	4	92	22498	2983561	1.942	0.848	3.95	3.523	6.554	3.524	0.01	1.52981804	0.66371837
Infliximab	Anaphylactic reaction	Anaphylactic responses	Allergic conditions	Immun	1968-2006	157	5375	22345	2978278	1.85	1.62	2.105	1.9	65.144	1.907	6.962e-16	1.88405	0.61518564
Infliximab	Anaphylactic shock	Anaphylactic responses	Allergic conditions	Immun	1968-2006	69	3899	22433	2979754	1.173	0.959	1.422	1.192	2.078	1.193	0.149	1.17631018	0.15956457
Infliximab	Anaphylactoid reaction	Anaphylactic responses	Allergic conditions	Immun	1968-2006	91	14802	22411	2968851	3.282	2.756	3.886	3.595	157.919	3.612	3.224e-36	-0.3079599	1.18845299
Infliximab	Anaplastic large cell lymphoma T- and null-cell types	Anaplastic large cell lymphomas T- and null-cell types	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	3	16	22499	2983637	2.568	0.984	5.837	12.806	26.632	12.811	2.462e-7	1.79730948	0.94312739
Infliximab	Anastomotic complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	40	22499	2983613	1.938	0.752	4.294	4.695	7.652	4.695	0.006	1.58656148	0.66165651
Infliximab	Anastomotic leak	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	8	52	22494	2983601	3.598	1.977	6.171	7.543	36.532	7.545	1.501e-9	2.62388206	1.28037814
Infliximab	Anastomotic stenosis	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	18	22501	2983635	1.124	0.26	3.514	4.399	2.36	4.4	0.124	0.79730935	0.11689375
Infliximab	Anastomotic ulcer	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	28	22499	2983625	2.136	0.828	4.747	6.273	11.505	6.274	0.001	1.68809108	0.75893492
Infliximab	Aneurysm	Aneurysms and dissections non-site specific	Aneurysms and artery dissections	Vasc	1968-2006	11	767	22491	2982886	0.933	0.561	1.476	0.98	0.004	0.98	0.947	0.80322547	-0.0693501
Infliximab	Aneurysm ruptured	Aneurysms and dissections non-site specific	Aneurysms and artery dissections	Vasc	1968-2006	2	83	22500	2983570	0.93	0.301	2.331	1.267	0.109	1.267	0.742	0.86368809	-0.0725707
Infliximab	Aneurysmectomy	Vascular therapeutic procedures NEC	Vascular therapeutic procedures	Surg	1968-2006	1	0	22501	2983653	1.364	0.311	4.328	1084.324	71.361	1091.976	2.975e-17	0.97840063	0.31042156
Infliximab	Anger	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	4	3165	22498	2980488	0.079	0.035	0.161	0.071	49.256	0.071	2.246e-12	-2.3181034	-2.5383074
Infliximab	Angina pectoris	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	50	9489	22452	2974164	0.527	0.416	0.66	0.522	21.782	0.521	3.055e-6	-0.5209737	-0.6405547
Infliximab	Angina unstable	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	25	1994	22477	2981659	1.006	0.719	1.378	1.033	0.025	1.033	0.874	0.67849733	0.00598207
Infliximab	Angiodysplasia	Vascular malformations and acquired anomalies	Vascular disorders NEC	Vasc	1968-2006	1	28	22501	2983625	0.899	0.208	2.806	1.77	0.311	1.77	0.577	0.70572945	-0.1064722
Infliximab	Angioneurotic oedema	Angioedemas	Angioedema and urticaria	Skin	1968-2006	104	12395	22398	2971258	1.109	0.942	1.299	1.12	1.313	1.12	0.252	0.13425985	0.10345871
Infliximab	Angiopathy	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	22	3209	22480	2980444	0.896	0.626	1.251	0.915	0.171	0.915	0.679	-0.143324	-0.1098149
Infliximab	Angioplasty	Vascular therapeutic procedures NEC	Vascular therapeutic procedures	Surg	1968-2006	7	448	22495	2983205	1.518	0.805	2.661	1.858	2.669	1.859	0.102	0.84953482	0.41739368
Infliximab	Angiosarcoma	Cardiovascular neoplasms malignant and unspecified	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	3	37	22499	2983616	2.087	0.809	4.633	5.609	10.391	5.61	0.001	1.61128199	0.73572763
Infliximab	Angiotensin converting enzyme increased	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	1	34	22501	2983619	0.837	0.194	2.611	1.434	0.126	1.434	0.723	0.65344776	-0.1779312
Infliximab	Angle closure glaucoma	Glaucomas (excl congenital)	Glaucoma and ocular hypertension	Eye	1968-2006	1	374	22501	2983279	0.194	0.045	0.607	0.145	4.959	0.145	0.026	-0.9396708	-1.6398971
Infliximab	Anhedonia	Mood alterations with depressive symptoms	Depressed mood disorders and disturbances	Psych	1968-2006	5	2130	22497	2981523	0.221	0.105	0.423	0.208	15.151	0.208	0.00009927	-1.5127673	-1.5095926
Infliximab	Animal bite	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	99	22501	2983554	0.511	0.118	1.595	0.529	0.407	0.529	0.523	0.18296925	-0.6713857
Infliximab	Anion gap abnormal	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	51	22501	2983602	0.84	0.194	2.622	1.447	0.133	1.447	0.715	0.51484364	-0.1743534
Infliximab	Anion gap increased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	324	22501	2983329	0.285	0.066	0.89	0.233	2.492	0.233	0.114	-0.7903501	-1.2552661
Infliximab	Anion gap normal	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	0	22501	2983653	1.373	0.313	4.364	1087.839	84.503	1095.499	3.835e-20	0.97840063	0.31699813
Infliximab	Anisocytosis	Red blood cell abnormal findings NEC	Red blood cell disorders	Blood	1968-2006	1	124	22501	2983529	0.544	0.126	1.698	0.589	0.281	0.589	0.596	0.03627232	-0.608806
Infliximab	Ankle fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	16	841	22486	2982812	1.043	0.685	1.536	1.091	0.117	1.091	0.732	1.18578745	0.04210118
Infliximab	Ankle operation	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	2	27	22500	2983626	1.51	0.489	3.792	3.926	3.852	3.926	0.05	1.29069204	0.41210965
Infliximab	Ankylosing spondylitis	Spondyloarthropathies	Joint disorders	Musc	1968-2006	28	77	22474	2983576	12.087	7.848	17.212	18.631	329.146	18.659	0	4.01039925	2.49213049
Infliximab	Ano-rectal ulcer	Anal and rectal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	8	22501	2983645	1.252	0.289	3.929	13.208	7.304	13.208	0.007	0.89509832	0.22474227
Infliximab	Anogenital warts	Papilloma viral infections	Viral infectious disorders	Infec	1968-2006	2	6	22500	2983647	2.135	0.675	5.58	22.975	34.525	22.983	4.207e-9	1.4902144	0.75846665
Infliximab	Anorectal disorder	Anal and rectal disorders NEC	Anal and rectal conditions NEC	Gastr	1968-2006	11	1506	22491	2982147	1.333	0.802	2.11	1.475	1.644	1.476	0.2	-0.0536528	0.28743204
Infliximab	Anorexia	Appetite disorders	Appetite and general nutritional disorders	Metab	1968-2006	134	20583	22368	2963070	0.678	0.587	0.779	0.674	21.049	0.671	4.476e-6	-0.2300886	-0.388608
Infliximab	Anorgasmia	Orgasmic disorders and disturbances	Sexual dysfunctions, disturbances and gender identity disorders	Psych	1968-2006	1	1814	22501	2981839	0.186	0.043	0.581	0.139	5.278	0.139	0.022	-2.878212	-1.6820086
Infliximab	Anosmia	Olfactory nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	5	1215	22497	2982438	0.266	0.126	0.508	0.252	11.102	0.251	0.001	-0.7673218	-1.324259
Infliximab	Anoxia	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	5	237	22497	2983416	1.261	0.598	2.408	1.556	0.958	1.556	0.328	1.08269643	0.23190506
Infliximab	Anoxic encephalopathy	Encephalopathies NEC	Encephalopathies	Nerv	1968-2006	2	418	22500	2983235	0.292	0.095	0.733	0.262	4.092	0.262	0.043	-0.4770433	-1.2310015
Infliximab	Antepartum haemorrhage	Haemorrhagic complications of pregnancy	Maternal complications of pregnancy	Preg	1968-2006	1	298	22501	2983355	0.312	0.072	0.974	0.26	2.065	0.26	0.151	-0.7061339	-1.1647521
Infliximab	Anterior chamber disorder	Anterior chamber structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	61	22501	2983592	0.795	0.184	2.481	1.258	0.051	1.258	0.822	0.43912725	-0.2294132
Infliximab	Anterior chamber opacity	Anterior chamber structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	7	22501	2983646	1.378	0.314	4.386	116.423	54.031	116.423	1.973e-13	0.90525186	0.32063317
Infliximab	Anti-erythrocyte antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	23	22501	2983630	0.905	0.209	2.824	1.767	0.334	1.767	0.563	0.75079293	-0.0998203
Infliximab	Anti-platelet antibody	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	22	22501	2983631	0.892	0.206	2.785	1.731	0.287	1.731	0.592	0.75997701	-0.1142891
Infliximab	Anti-platelet antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	66	22501	2983587	0.678	0.157	2.117	0.883	0.015	0.883	0.903	0.40270872	-0.388608
Infliximab	Anti-prothrombin antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	1	22501	2983652	1.316	0.302	4.151	46.46	16.033	46.46	0.00006224	0.967721	0.27459683
Infliximab	Antibody test abnormal	Immunology analyses NEC	Immunology and allergy investigations	Inv	1968-2006	5	115	22497	2983538	1.98	0.939	3.785	3.163	6.78	3.164	0.009	1.64940621	0.68309684
Infliximab	Antibody test positive	Immunology analyses NEC	Immunology and allergy investigations	Inv	1968-2006	22	738	22480	2982915	1.87	1.306	2.611	2.066	11.507	2.068	0.001	1.77061004	0.62593843
Infliximab	Anticonvulsant drug level below therapeutic	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	2	196	22500	2983457	0.516	0.167	1.294	0.527	0.835	0.527	0.361	0.26247223	-0.6616485
Infliximab	Anticonvulsant toxicity	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	1	74	22501	2983579	0.608	0.141	1.898	0.72	0.11	0.72	0.741	0.34628598	-0.4975804
Infliximab	Antimitochondrial antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	59	22501	2983594	0.783	0.181	2.443	1.208	0.035	1.208	0.851	0.453956	-0.2446226
Infliximab	Antineutrophil cytoplasmic antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	4	113	22498	2983540	1.249	0.545	2.537	1.619	0.93	1.619	0.335	1.40354167	0.22234323
Infliximab	Antinuclear antibody	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	6	49	22496	2983604	4.031	1.972	8.027	12.934	52.295	12.94	4.776e-13	2.29906427	1.39401448
Infliximab	Antinuclear antibody increased	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	2	36	22500	2983617	1.541	0.499	3.871	3.958	4.266	3.958	0.039	1.2129632	0.43243156
Infliximab	Antinuclear antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	229	3821	22273	2979832	8.018	7.169	8.953	10.133	1500.185	10.248	0	2.8639944	2.08168901
Infliximab	Antiphospholipid antibodies	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	13	22501	2983640	1.116	0.258	3.491	4.303	2.246	4.304	0.134	0.84537553	0.10975086
Infliximab	Antiphospholipid antibodies positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	9	86	22493	2983567	3.07	1.75	5.085	5.02	25.3	5.022	4.907e-7	2.5361169	1.12167756
Infliximab	Antiphospholipid syndrome	Blood autoimmune disorders	Autoimmune disorders	Immun	1968-2006	12	134	22490	2983519	3.462	2.127	5.398	5.216	36.779	5.219	1.323e-9	2.6240606	1.24184646
Infliximab	Anuria	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	19	3364	22483	2980289	0.635	0.431	0.907	0.637	3.888	0.636	0.049	-0.4087792	-0.4541303
Infliximab	Anxiety	Anxiety symptoms	Anxiety disorders and symptoms	Psych	1968-2006	149	41090	22353	2942563	0.365	0.318	0.417	0.359	172.916	0.355	1.707e-39	-1.0766916	-1.0078579
Infliximab	Anxiety disorder	Anxiety disorders NEC (incl obsessive compulsive disorder)	Anxiety disorders and symptoms	Psych	1968-2006	2	328	22500	2983325	0.479	0.155	1.2	0.48	1.116	0.48	0.291	-0.221034	-0.7360547
Infliximab	Aortic aneurysm	Aortic aneurysms and dissections	Aneurysms and artery dissections	Vasc	1968-2006	19	739	22483	2982914	1.889	1.284	2.7	2.113	10.612	2.115	0.001	1.57220849	0.63604759
Infliximab	Aortic aneurysm repair	Aortic therapeutic procedures	Vascular therapeutic procedures	Surg	1968-2006	1	18	22501	2983635	1.236	0.285	3.878	8.33	6.171	8.33	0.013	0.79730935	0.21188036
Infliximab	Aortic aneurysm rupture	Aortic aneurysms and dissections	Aneurysms and artery dissections	Vasc	1968-2006	7	200	22495	2983453	1.99	1.055	3.489	2.707	7.247	2.708	0.007	1.63887188	0.68813464
Infliximab	Aortic arteriosclerosis	Aortic necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	14	489	22488	2983164	1.729	1.102	2.61	1.971	6.353	1.972	0.012	1.64330443	0.54754321
Infliximab	Aortic bypass	Aortic therapeutic procedures	Vascular therapeutic procedures	Surg	1968-2006	2	12	22500	2983641	1.878	0.605	4.755	10.402	13.284	10.406	0.0002677	1.43033808	0.63020738
Infliximab	Aortic calcification	Site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	3	82	22499	2983571	1.528	0.594	3.379	2.594	2.825	2.595	0.093	1.27872578	0.42395969
Infliximab	Aortic dilatation	Site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	3	99	22499	2983554	1.373	0.534	3.037	2.136	1.711	2.136	0.191	1.17066919	0.31699813
Infliximab	Aortic disorder	Site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	102	22501	2983551	0.549	0.127	1.712	0.599	0.265	0.599	0.607	0.16455763	-0.5996568
Infliximab	Aortic dissection	Aortic aneurysms and dissections	Aneurysms and artery dissections	Vasc	1968-2006	5	263	22497	2983390	1.13	0.536	2.158	1.34	0.419	1.341	0.517	0.98612051	0.12221763
Infliximab	Aortic embolus	Aortic embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	36	22501	2983617	0.911	0.211	2.844	1.837	0.357	1.837	0.55	0.63643321	-0.0932124
Infliximab	Aortic occlusion	Aortic necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	58	22501	2983595	0.776	0.18	2.423	1.189	0.029	1.189	0.865	0.46142791	-0.2536028
Infliximab	Aortic rupture	Arterial and aortic injuries	Vascular injuries	Vasc	1968-2006	1	26	22501	2983627	1.04	0.241	3.249	2.881	1.209	2.881	0.271	0.72358631	0.03922071
Infliximab	Aortic thrombosis	Aortic embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	2	109	22500	2983544	0.869	0.282	2.178	1.129	0.028	1.129	0.867	0.7015412	-0.1404122
Infliximab	Aortic valve calcification	Aortic valvular disorders	Cardiac valve disorders	Card	1968-2006	5	75	22497	2983578	2.267	1.074	4.337	4.074	10.468	4.075	0.001	1.89707354	0.81845737
Infliximab	Aortic valve disease	Aortic valvular disorders	Cardiac valve disorders	Card	1968-2006	7	378	22495	2983275	1.491	0.79	2.612	1.832	2.465	1.833	0.116	1.03223549	0.39944704
Infliximab	Aortic valve incompetence	Aortic valvular disorders	Cardiac valve disorders	Card	1968-2006	28	1824	22474	2981829	1.692	1.232	2.279	1.816	9.784	1.818	0.002	0.95262621	0.52591126
Infliximab	Aortic valve replacement	Cardiac valve therapeutic procedures	Cardiac therapeutic procedures	Surg	1968-2006	5	136	22497	2983517	1.866	0.885	3.566	2.825	5.541	2.825	0.019	1.53461718	0.6237971
Infliximab	Aortic valve sclerosis	Aortic valvular disorders	Cardiac valve disorders	Card	1968-2006	5	315	22497	2983338	1.267	0.601	2.419	1.566	0.983	1.566	0.321	0.8104321	0.2366519
Infliximab	Aortic valve stenosis	Aortic valvular disorders	Cardiac valve disorders	Card	1968-2006	20	747	22482	2982906	1.992	1.367	2.823	2.261	13.065	2.262	0.0003009	1.62810396	0.68913916
Infliximab	Aortitis	Aortic inflammatory disorders	Vascular inflammations	Vasc	1968-2006	2	19	22500	2983634	1.718	0.556	4.328	6.294	7.752	6.294	0.005	1.36348501	0.54116082
Infliximab	Aorto-duodenal fistula	Vascular malformations and acquired anomalies	Vascular disorders NEC	Vasc	1968-2006	2	9	22500	2983644	1.932	0.622	4.908	12.212	16.206	12.216	0.00005681	1.45996566	0.65855574
Infliximab	Apallic syndrome	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	1	259	22501	2983394	0.283	0.065	0.884	0.234	2.538	0.234	0.111	-0.56981	-1.2623084
Infliximab	Apathy	Mood disorders NEC	Mood disorders and disturbances NEC	Psych	1968-2006	4	2304	22498	2981349	0.211	0.092	0.428	0.195	13.326	0.195	0.0002618	-1.8819106	-1.5558971
Infliximab	Aphagia	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	2	211	22500	2983442	0.508	0.165	1.273	0.515	0.893	0.515	0.345	0.19863644	-0.6772738
Infliximab	Aphasia	Cortical dysfunction NEC	Neurological disorders NEC	Nerv	1968-2006	30	4088	22472	2979565	0.698	0.514	0.931	0.699	3.817	0.699	0.051	-0.0506865	-0.3595362
Infliximab	Aphonia	Speech and language abnormalities	Neurological disorders NEC	Nerv	1968-2006	12	625	22490	2983028	1.041	0.64	1.62	1.105	0.116	1.105	0.733	1.16119127	0.04018179
Infliximab	Aphthous stomatitis	Stomatitis and ulceration	Oral soft tissue conditions	Gastr	1968-2006	13	377	22489	2983276	1.677	1.051	2.567	1.906	5.418	1.907	0.02	1.82574715	0.51700648
Infliximab	Aplasia	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	4	445	22498	2983208	0.622	0.271	1.263	0.647	0.758	0.647	0.384	0.18624665	-0.4748152
Infliximab	Aplastic anaemia	Marrow depression and hypoplastic anaemias	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	8	3181	22494	2980472	0.522	0.288	0.886	0.523	3.477	0.522	0.062	-1.4788247	-0.6500877
Infliximab	Apnoea	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	11	12109	22491	2971544	0.369	0.222	0.584	0.362	12.388	0.361	0.0004322	-2.9509379	-0.9969586
Infliximab	Apparent life threatening event	Neonatal hypoxic conditions	Neonatal respiratory disorders	Resp	1968-2006	2	8	22500	2983645	1.95	0.627	4.961	14.697	17.342	14.697	0.00003122	1.46997828	0.66782937
Infliximab	Appendiceal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	15	22500	2983638	1.746	0.565	4.4	6.769	8.471	6.769	0.004	1.40130667	0.55732746
Infliximab	Appendicectomy	Large intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	12	226	22490	2983427	2.519	1.549	3.919	3.32	17.637	3.322	0.00002674	2.21362451	0.923862
Infliximab	Appendicitis	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	33	687	22469	2982966	2.78	2.075	3.662	3.183	45.52	3.187	1.511e-11	2.40060406	1.02245093
Infliximab	Appendicitis perforated	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	12	199	22490	2983454	2.511	1.544	3.906	3.303	17.503	3.305	0.00002868	2.32246666	0.92068108
Infliximab	Appendix disorder	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	5	127	22497	2983526	2.059	0.976	3.936	3.384	7.666	3.384	0.006	1.58269883	0.72222043
Infliximab	Appetite disorder	Appetite disorders	Appetite and general nutritional disorders	Metab	1968-2006	1	256	22501	2983397	0.333	0.077	1.04	0.283	1.769	0.283	0.184	-0.5587702	-1.0996128
Infliximab	Application site bleeding	Application and instillation site reactions	Administration site reactions	Genrl	1968-2006	1	82	22501	2983571	0.537	0.124	1.677	0.578	0.304	0.578	0.581	0.29198681	-0.6217572
Infliximab	Application site erythema	Application and instillation site reactions	Administration site reactions	Genrl	1968-2006	1	2408	22501	2981245	0.045	0.01	0.141	0.03	31.141	0.03	2.4e-8	-3.2623668	-3.1010928
Infliximab	Application site infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	37	22501	2983616	0.819	0.189	2.557	1.355	0.09	1.355	0.764	0.62800058	-0.1996712
Infliximab	Application site necrosis	Application and instillation site reactions	Administration site reactions	Genrl	1968-2006	1	20	22501	2983633	1.149	0.266	3.595	5.396	2.902	5.396	0.088	0.77852244	0.138892
Infliximab	Application site reaction	Application and instillation site reactions	Administration site reactions	Genrl	1968-2006	1	35882	22501	2947771	0.014	0.003	0.046	0.01	102.031	0.01	5.466e-24	-7.1029453	-4.2686979
Infliximab	Aptyalism	Oral dryness and saliva altered	Salivary gland conditions	Gastr	1968-2006	1	118	22501	2983535	0.409	0.094	1.276	0.376	1.008	0.376	0.315	0.07014349	-0.8940401
Infliximab	Arachnoiditis	Central nervous system inflammatory disorders NEC	Central nervous system infections and inflammations	Nerv	1968-2006	1	701	22501	2982952	0.371	0.086	1.158	0.334	1.341	0.334	0.247	-1.6561153	-0.9915532
Infliximab	Areflexia	Abnormal reflexes	Neurological disorders NEC	Nerv	1968-2006	4	497	22498	2983156	0.429	0.187	0.871	0.42	3.163	0.42	0.075	0.06287874	-0.8462984
Infliximab	Arm amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	61	22501	2983592	0.727	0.168	2.27	1.024	0.001	1.024	0.981	0.43912725	-0.3188288
Infliximab	Arnold-Chiari malformation	Cerebellar disorders congenital	Neurological disorders congenital	Cong	1968-2006	1	86	22501	2983567	0.606	0.14	1.893	0.711	0.113	0.711	0.737	0.26558476	-0.5008753
Infliximab	Arrhythmia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	76	15055	22426	2968598	0.58	0.479	0.697	0.575	23.672	0.574	1.143e-6	-0.5875293	-0.5447272
Infliximab	Arrhythmia supraventricular	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	5	1007	22497	2982646	0.346	0.164	0.66	0.333	6.685	0.333	0.01	-0.5265222	-1.0613165
Infliximab	Arterial bypass operation	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	4	68	22498	2983585	1.953	0.852	3.973	3.586	6.707	3.587	0.01	1.68911542	0.66936665
Infliximab	Arterial disorder	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	6	443	22496	2983210	0.855	0.432	1.557	0.922	0.038	0.922	0.845	0.67167422	-0.1566538
Infliximab	Arterial fibrosis	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	7	22501	2983646	1.207	0.279	3.781	7.733	4.748	7.733	0.029	0.90525186	0.18813794
Infliximab	Arterial graft	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	1	16	22501	2983637	1.109	0.256	3.467	4.072	2.121	4.073	0.145	0.81634411	0.10345871
Infliximab	Arterial haemorrhage	Haemorrhages NEC	Vascular haemorrhagic disorders	Vasc	1968-2006	2	64	22500	2983589	1.06	0.344	2.658	1.604	0.448	1.605	0.503	0.99488192	0.05826891
Infliximab	Arterial injury	Cardiovascular injuries	Injuries NEC	Inj&P	1968-2006	1	124	22501	2983529	0.539	0.125	1.682	0.577	0.297	0.577	0.586	0.03627232	-0.6180397
Infliximab	Arterial insufficiency	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	23	22501	2983630	1.076	0.249	3.363	3.604	1.621	3.604	0.203	0.75079293	0.07325046
Infliximab	Arterial occlusive disease	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	20	1603	22482	2982050	0.978	0.671	1.386	1.008	0.001	1.008	0.973	0.6638595	-0.0222456
Infliximab	Arterial repair	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	1	26	22501	2983627	1.089	0.252	3.404	3.562	1.796	3.562	0.18	0.72358631	0.08525984
Infliximab	Arterial rupture	Arterial and aortic injuries	Vascular injuries	Vasc	1968-2006	3	164	22499	2983489	1.056	0.41	2.334	1.367	0.289	1.367	0.591	0.8191261	0.05448819
Infliximab	Arterial stenosis	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	6	231	22496	2983422	1.664	0.84	3.031	2.216	3.744	2.216	0.053	1.324426	0.50922434
Infliximab	Arterial stent insertion	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	3	25	22499	2983628	2.056	0.798	4.563	5.9	9.825	5.9	0.002	1.71463043	0.72076235
Infliximab	Arterial thrombosis	Non-site specific embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	4	817	22498	2982836	0.689	0.301	1.4	0.734	0.38	0.734	0.537	-0.5263284	-0.372514
Infliximab	Arterial thrombosis limb	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	6	290	22496	2983363	1.145	0.578	2.086	1.326	0.462	1.327	0.496	1.11126393	0.13540464
Infliximab	Arteriogram carotid abnormal	Vascular imaging procedures NEC	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	16	22501	2983637	1.134	0.262	3.546	4.923	2.572	4.923	0.109	0.81634411	0.12575121
Infliximab	Arteriopathic disease	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	70	22501	2983583	0.742	0.172	2.315	1.071	0.004	1.071	0.947	0.37422158	-0.298406
Infliximab	Arteriosclerosis	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	30	3014	22472	2980639	0.818	0.602	1.092	0.826	1.071	0.826	0.301	0.36990214	-0.2008929
Infliximab	Arteriosclerosis coronary artery	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	48	1651	22454	2982002	1.943	1.526	2.446	2.056	24.992	2.06	5.756e-7	1.82512137	0.66423317
Infliximab	Arteriosclerosis obliterans	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	30	22501	2983623	0.995	0.23	3.109	2.466	0.828	2.466	0.363	0.68809089	-0.0050125
Infliximab	Arteriospasm coronary	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	4	599	22498	2983054	0.531	0.232	1.078	0.537	1.574	0.537	0.21	-0.1522059	-0.6329933
Infliximab	Arteriovenous malformation	Vascular anomalies congenital NEC	Cardiac and vascular disorders congenital	Cong	1968-2006	4	175	22498	2983478	1.193	0.521	2.423	1.517	0.683	1.517	0.409	1.08457504	0.17647114
Infliximab	Arteritis	Arterial inflammations	Vascular inflammations	Vasc	1968-2006	3	349	22499	2983304	1.122	0.436	2.48	1.503	0.491	1.503	0.484	0.12710468	0.11511281
Infliximab	Arteritis coronary	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	1	6	22501	2983647	1.271	0.293	3.996	14.859	8.971	14.859	0.003	0.91547736	0.23980399
Infliximab	Artery dissection	Aneurysms and dissections non-site specific	Aneurysms and artery dissections	Vasc	1968-2006	2	61	22500	2983592	1.142	0.37	2.864	1.88	0.78	1.88	0.377	1.01673229	0.13278111
Infliximab	Arthralgia	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	834	36770	21668	2946883	2.29	2.163	2.424	2.365	636.439	2.422	0	1.53491031	0.82855182
Infliximab	Arthritis	Arthropathies NEC	Joint disorders	Musc	1968-2006	184	8358	22318	2975295	2.632	2.328	2.966	2.788	197.185	2.804	8.595e-45	1.49547021	0.96774401
Infliximab	Arthritis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	117	489	22385	2983164	10.768	9.103	12.633	14.48	1101.075	14.56	0	4.40268857	2.37657877
Infliximab	Arthritis enteropathic	Arthropathies NEC	Joint disorders	Musc	1968-2006	6	7	22496	2983646	16.975	3.731	44.628	76.219	178.379	76.299	1.095e-40	2.66253911	2.83174167
Infliximab	Arthritis fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	6	22501	2983647	1.271	0.293	3.993	11.691	8.851	11.691	0.003	0.91547736	0.23980399
Infliximab	Arthritis infective	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	36	279	22466	2983374	5.375	4.054	7.034	7.227	164.531	7.236	1.158e-37	3.45092713	1.68175857
Infliximab	Arthritis salmonella	Salmonella infections	Bacterial infectious disorders	Infec	1968-2006	2	5	22500	2983648	1.923	0.619	4.884	11.948	15.791	11.948	0.00007075	1.50043989	0.65388647
Infliximab	Arthrodesis	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	12	46	22490	2983607	5.941	3.456	10.994	13.604	103.034	13.607	3.295e-24	3.16938008	1.78187747
Infliximab	Arthropathy	Arthropathies NEC	Joint disorders	Musc	1968-2006	82	4800	22420	2978853	1.874	1.559	2.239	1.953	36.497	1.957	1.529e-9	1.13139452	0.62807518
Infliximab	Arthropod bite	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	10	405	22492	2983248	1.283	0.754	2.073	1.429	1.244	1.429	0.265	1.4105206	0.24920109
Infliximab	Arthropod sting	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	80	22501	2983573	0.565	0.131	1.762	0.632	0.216	0.632	0.642	0.30537124	-0.5709295
Infliximab	Arthroscopy	Musculoskeletal and soft tissue imaging procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	2	26	22500	2983627	1.639	0.531	4.122	5.269	5.95	5.269	0.015	1.29959284	0.4940863
Infliximab	Asbestosis	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	1	40	22501	2983613	0.931	0.215	2.907	1.96	0.444	1.96	0.505	0.60299444	-0.071496
Infliximab	Ascites	Peritoneal and retroperitoneal disorders	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	90	5369	22412	2978284	1.343	1.126	1.591	1.37	8.731	1.372	0.003	1.10677716	0.29490592
Infliximab	Ascites infection	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	3	13	22499	2983640	2.561	0.982	5.818	14.501	26.352	14.506	2.845e-7	1.8259566	0.94039781
Infliximab	Asocial behaviour	Behaviour and socialisation disturbances	Personality disorders and disturbances in behaviour	Psych	1968-2006	1	26	22501	2983627	0.933	0.216	2.913	1.996	0.458	1.996	0.499	0.72358631	-0.0693501
Infliximab	Aspartate aminotransferase	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	7	203	22495	2983450	1.213	0.643	2.125	1.393	0.752	1.394	0.386	1.62621866	0.19309663
Infliximab	Aspartate aminotransferase abnormal	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	2	141	22500	2983512	0.607	0.197	1.521	0.653	0.356	0.653	0.551	0.52414576	-0.4992265
Infliximab	Aspartate aminotransferase increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	162	24684	22340	2958969	0.655	0.575	0.744	0.651	30.303	0.647	3.695e-8	-0.2208357	-0.42312
Infliximab	Aspergilloma	Aspergillus infections	Fungal infectious disorders	Infec	1968-2006	6	142	22496	2983511	2.723	1.373	4.974	4.88	17.57	4.882	0.00002769	1.72069017	1.00173421
Infliximab	Aspergillosis	Aspergillus infections	Fungal infectious disorders	Infec	1968-2006	56	528	22446	2983125	4.431	3.542	5.49	5.309	173.268	5.322	1.431e-39	3.39648744	1.48862529
Infliximab	Asphyxia	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	4	741	22498	2982912	0.637	0.278	1.295	0.668	0.655	0.668	0.418	-0.4066012	-0.4509856
Infliximab	Aspiration	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	17	1673	22485	2981980	0.689	0.458	1.004	0.695	2.236	0.695	0.135	0.3874296	-0.372514
Infliximab	Aspiration bone marrow abnormal	Bone marrow and immune tissue analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	112	22501	2983541	0.585	0.135	1.826	0.666	0.161	0.666	0.688	0.10482889	-0.5361434
Infliximab	Aspiration joint	Musculoskeletal and soft tissue histopathology procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	1	12	22501	2983641	1.152	0.266	3.604	5.479	2.992	5.48	0.084	0.85518395	0.14149956
Infliximab	Aspiration joint abnormal	Musculoskeletal and soft tissue histopathology procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	4	20	22498	2983633	3.237	1.374	7.046	15.722	40.706	15.722	1.769e-10	2.07272126	1.17464697
Infliximab	Asterixis	Tremor (excl congenital)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	2	137	22500	2983516	0.711	0.23	1.781	0.824	0.074	0.824	0.785	0.54516365	-0.3410828
Infliximab	Asthenia	Asthenic conditions	General system disorders NEC	Genrl	1968-2006	503	79036	21999	2904617	0.792	0.736	0.852	0.789	28.767	0.783	8.165e-8	-0.292364	-0.2331939
Infliximab	Asthenopia	Ocular sensation disorders	Ocular sensory symptoms NEC	Eye	1968-2006	1	230	22501	2983423	0.327	0.076	1.022	0.282	1.846	0.282	0.174	-0.459379	-1.1177951
Infliximab	Asthma	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	110	19900	22392	2963753	0.962	0.821	1.122	0.966	0.125	0.966	0.723	-0.4623884	-0.0387408
Infliximab	Astrocytoma	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	5	93	22497	2983560	2.123	1.006	4.059	3.563	8.505	3.563	0.004	1.78033882	0.75283018
Infliximab	Astrocytoma malignant	Glial tumours malignant	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	11	22501	2983642	1.102	0.255	3.445	3.933	2.008	3.934	0.156	0.86505951	0.09712671
Infliximab	Atelectasis	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	58	2276	22444	2981377	1.918	1.54	2.367	2.023	28.558	2.026	9.091e-8	1.66353474	0.65128298
Infliximab	Atlantoaxial instability	Joint related disorders NEC	Joint disorders	Musc	1968-2006	1	0	22501	2983653	1.355	0.31	4.295	1080.439	60.862	1088.06	6.122e-15	0.97840063	0.30380145
Infliximab	Atopy	Atopic disorders	Allergic conditions	Immun	1968-2006	1	19	22501	2983634	1.102	0.255	3.445	4.104	1.996	4.104	0.158	0.78788532	0.09712671
Infliximab	Atrial bigeminy				1968-2006	1	13	22501	2983640	1.09	0.252	3.407	3.712	1.822	3.712	0.177	0.84537553	0.0861777
Infliximab	Atrial fibrillation	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	259	13647	22243	2970006	1.677	1.513	1.855	1.718	74.827	1.731	5.14e-18	1.28942317	0.51700648
Infliximab	Atrial flutter	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	19	1629	22483	2982024	1.111	0.755	1.588	1.16	0.409	1.161	0.522	0.57306983	0.10526051
Infliximab	Atrial hypertrophy	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	2	50	22500	2983603	1.282	0.416	3.216	2.443	1.595	2.444	0.207	1.09980628	0.24842136
Infliximab	Atrial pressure increased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	15	22501	2983638	1.121	0.259	3.507	4.421	2.332	4.421	0.127	0.82595649	0.11422114
Infliximab	Atrial septal defect	Cardiac septal defects congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	2	574	22500	2983079	0.269	0.087	0.675	0.241	4.796	0.241	0.029	-0.8352835	-1.3130439
Infliximab	Atrial tachycardia	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	10	366	22492	2983287	1.639	0.962	2.647	1.932	4.276	1.933	0.039	1.51692969	0.4940863
Infliximab	Atrioventricular block	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	12	2818	22490	2980835	0.625	0.385	0.973	0.632	2.559	0.631	0.11	-0.7831723	-0.4700036
Infliximab	Atrioventricular block complete				1968-2006	11	2651	22491	2981002	0.603	0.363	0.954	0.607	2.766	0.607	0.096	-0.8143758	-0.5058381
Infliximab	Atrioventricular block first degree	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	2	1575	22500	2982078	0.171	0.055	0.429	0.143	10.051	0.143	0.002	-2.1051978	-1.7660917
Infliximab	Atrioventricular block second degree	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	6	1109	22496	2982544	0.684	0.345	1.245	0.709	0.699	0.709	0.403	-0.4283877	-0.3797974
Infliximab	Atrioventricular extrasystoles	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	2	4	22500	2983649	2.091	0.665	5.415	25.95	29.595	25.957	5.326e-8	1.51073838	0.73764242
Infliximab	Atrophy	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	7	583	22495	2983070	0.85	0.451	1.489	0.906	0.067	0.906	0.795	0.55156261	-0.1625189
Infliximab	Attention deficit/hyperactivity disorder	Attention deficit and disruptive behaviour disorders	Cognitive and attention disorders and disturbances	Psych	1968-2006	1	4185	22501	2979468	0.136	0.031	0.427	0.099	8.225	0.099	0.004	-4.0278213	-1.9951004
Infliximab	Atypical mycobacterial infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	32	74	22470	2983579	13.667	9.531	18.541	22.256	412.958	22.281	0	4.19077879	2.61498417
Infliximab	Auricular swelling	External ear disorders NEC	External ear disorders (excl congenital)	Ear	1968-2006	2	197	22500	2983456	0.626	0.203	1.57	0.687	0.282	0.687	0.595	0.25812752	-0.4684049
Infliximab	Autoantibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	7	121	22495	2983532	2.709	1.435	4.756	4.528	17.476	4.53	0.0000291	2.01963173	0.99657956
Infliximab	Autoimmune disorder	Autoimmune disorders NEC	Autoimmune disorders	Immun	1968-2006	22	664	22480	2982989	2.007	1.402	2.803	2.233	14.354	2.234	0.0001515	1.89535559	0.69664107
Infliximab	Autoimmune hepatitis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	26	602	22476	2983051	2.321	1.669	3.16	2.617	24.497	2.62	7.441e-7	2.2325978	0.84199813
Infliximab	Autoimmune thrombocytopenia	Thrombocytopenias	Platelet disorders	Blood	1968-2006	1	111	22501	2983542	0.444	0.103	1.386	0.425	0.758	0.425	0.384	0.11069173	-0.8119307
Infliximab	Autoimmune thyroiditis	Acute and chronic thyroiditis	Thyroid gland disorders	Endo	1968-2006	4	200	22498	2983453	0.859	0.375	1.745	0.967	0.004	0.967	0.948	0.97356425	-0.1519864
Infliximab	Autonomic nervous system imbalance	Autonomic nervous system disorders	Neuromuscular disorders	Nerv	1968-2006	3	269	22499	2983384	0.734	0.285	1.623	0.816	0.122	0.816	0.727	0.38685688	-0.3092463
Infliximab	Autonomic neuropathy	Autonomic nervous system disorders	Neuromuscular disorders	Nerv	1968-2006	1	124	22501	2983529	0.527	0.122	1.645	0.557	0.34	0.557	0.56	0.03627232	-0.6405547
Infliximab	Axillary mass	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	2	49	22500	2983604	1.214	0.393	3.043	2.153	1.155	2.153	0.283	1.10760111	0.19392069
Infliximab	Axillary vein thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	2	52	22500	2983601	1.09	0.353	2.732	1.708	0.559	1.708	0.455	1.0843418	0.0861777
Infliximab	Azotaemia	Renal disorders NEC	Renal disorders (excl nephropathies)	Renal	1968-2006	3	428	22499	2983225	0.439	0.17	0.97	0.432	2.231	0.432	0.135	-0.0903962	-0.8232559
Infliximab	B-cell lymphoma	B-cell lymphomas NEC	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	82	305	22420	2983348	11.478	9.345	13.89	16.095	835.36	16.146	0	4.40174784	2.44043216
Infliximab	B-cell lymphoma stage I	B-cell lymphomas NEC	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	5	22501	2983648	1.251	0.288	3.926	12.926	7.228	12.926	0.007	0.92577585	0.22394323
Infliximab	B-cell lymphoma stage II	B-cell lymphomas NEC	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	3	3	22499	2983650	6.655	1.358	59.768	144.695	189.553	144.695	3.98e-43	1.9257759	1.89536845
Infliximab	B-cell lymphoma stage III	B-cell lymphomas NEC	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	6	22501	2983647	1.177	0.272	3.685	6.498	3.692	6.498	0.055	0.91547736	0.16296883
Infliximab	B-cell lymphoma stage IV	B-cell lymphomas NEC	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	4	9	22498	2983644	3.541	1.457	8.862	23.05	53.74	23.054	2.288e-13	2.17711219	1.26440917
Infliximab	B-cell small lymphocytic lymphoma	B-cell small lymphocytic lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	2	25	22500	2983628	1.592	0.516	4.002	4.677	5.097	4.677	0.024	1.30854889	0.46499109
Infliximab	B-cell small lymphocytic lymphoma stage I	B-cell small lymphocytic lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	0	22501	2983653	1.399	0.317	4.473	1096.538	154.561	1104.269	1.746e-35	0.97840063	0.3357577
Infliximab	B-cell small lymphocytic lymphoma stage III	B-cell small lymphocytic lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	2	0	22500	2983653	2.406	0.718	7.406	1803.933	115.81	1816.719	5.231e-27	1.55268351	0.87796562
Infliximab	B-cell small lymphocytic lymphoma stage IV	B-cell small lymphocytic lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	0	22501	2983653	1.344	0.308	4.254	1075.473	51.196	1083.041	8.358e-13	0.97840063	0.29565024
Infliximab	B-cell type acute leukaemia	Leukaemias acute lymphocytic	Leukaemias	Neopl	1968-2006	2	12	22500	2983641	1.844	0.595	4.662	8.588	11.865	8.588	0.001	1.43033808	0.61193713
Infliximab	B-cell unclassifiable lymphoma high grade	B-cell unclassifiable lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	4	22501	2983649	1.285	0.296	4.043	18.119	10.571	18.119	0.001	0.93614837	0.25075872
Infliximab	B-cell unclassifiable lymphoma low grade	B-cell unclassifiable lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	3	2	22499	2983651	3.721	1.187	24.78	83.559	92.58	83.559	6.466e-22	1.93614842	1.31399245
Infliximab	BK virus infection	Polyomavirus infections	Viral infectious disorders	Infec	1968-2006	1	42	22501	2983611	0.818	0.189	2.554	1.352	0.089	1.352	0.766	0.58656124	-0.2008929
Infliximab	Babesiosis	Babesia infections	Protozoal infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.319	0.303	4.163	28.824	16.683	28.824	0.00004417	0.95711984	0.27687387
Infliximab	Bacillus infection	Bacillary infections	Bacterial infectious disorders	Infec	1968-2006	10	121	22492	2983532	3.024	1.774	4.891	4.499	25.185	4.501	5.208e-7	2.46261182	1.10658046
Infliximab	Back disorder	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	7	934	22495	2982719	0.504	0.267	0.883	0.5	3.407	0.5	0.065	-0.0191455	-0.685179
Infliximab	Back injury	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	5	751	22497	2982902	0.446	0.212	0.852	0.439	3.52	0.439	0.061	-0.1615221	-0.8074363
Infliximab	Back pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	400	27861	22102	2955792	1.379	1.27	1.496	1.396	44.092	1.404	3.133e-11	0.89147797	0.3213586
Infliximab	Bacteraemia	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	27	726	22475	2982927	1.779	1.288	2.409	1.926	11.454	1.927	0.001	2.06575432	0.57605141
Infliximab	Bacteria blood identified	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	4	105	22498	2983548	1.682	0.734	3.419	2.623	3.857	2.624	0.05	1.45035329	0.51998356
Infliximab	Bacteria sputum identified	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	4	96	22498	2983557	1.969	0.859	4.005	3.655	6.871	3.656	0.009	1.50489798	0.6775258
Infliximab	Bacteria stool identified	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	5	130	22497	2983523	1.65	0.782	3.152	2.318	3.532	2.319	0.06	1.56649294	0.50077529
Infliximab	Bacteria urine	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	2	61	22500	2983592	1.086	0.352	2.722	1.687	0.542	1.687	0.462	1.01673229	0.08250122
Infliximab	Bacteria urine identified	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	7	201	22495	2983452	1.389	0.736	2.434	1.657	1.757	1.657	0.185	1.6346418	0.32858406
Infliximab	Bacterial DNA test positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	1	22501	2983652	1.358	0.31	4.308	87.794	33.265	87.794	8.04e-9	0.967721	0.30601303
Infliximab	Bacterial culture positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	6	47	22496	2983606	3.042	1.531	5.577	6.711	24.239	6.714	8.51e-7	2.3144463	1.11251519
Infliximab	Bacterial food poisoning	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	4	22501	2983649	1.264	0.292	3.972	12.796	8.338	12.796	0.004	0.93614837	0.2342813
Infliximab	Bacterial infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	115	3437	22387	2980216	3.061	2.62	3.558	3.329	172.108	3.342	2.564e-39	2.05951839	1.11874166
Infliximab	Bacterial pericarditis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	2	22500	2983651	2.236	0.695	6.035	59.079	49.972	59.079	1.56e-12	1.53155852	0.80468856
Infliximab	Bacterial pyelonephritis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	23	22501	2983630	1.028	0.238	3.213	2.85	1.102	2.851	0.294	0.75079293	0.02761517
Infliximab	Bacterial sepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	22	403	22480	2983250	2.561	1.789	3.576	2.999	27.403	3.002	1.651e-7	2.44858937	0.94039781
Infliximab	Bacteriuria	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	3	178	22499	2983475	1.021	0.397	2.258	1.301	0.203	1.301	0.653	0.75344467	0.02078254
Infliximab	Bacteroides infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	4	39	22498	2983614	2.604	1.133	5.337	6.871	18.319	6.873	0.00001869	1.9084897	0.95704872
Infliximab	Balance disorder	Cerebellar coordination and balance disturbances	Neurological disorders NEC	Nerv	1968-2006	48	6041	22454	2977612	0.513	0.403	0.646	0.508	22.711	0.507	1.883e-6	0.05936885	-0.6674794
Infliximab	Balanitis	Penile and scrotal infections and inflammations	Male reproductive tract infections and inflammations	Repro	1968-2006	3	303	22499	2983350	1.971	0.765	4.37	4.74	8.155	4.743	0.004	0.27070541	0.67854103
Infliximab	Balanitis candida	Candida infections	Fungal infectious disorders	Infec	1968-2006	1	6	22501	2983647	1.293	0.298	4.069	14.712	11.49	14.726	0.001	0.91547736	0.2569651
Infliximab	Band neutrophil count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	7	22501	2983646	1.157	0.267	3.622	5.718	3.144	5.718	0.076	0.90525186	0.14583045
Infliximab	Band neutrophil count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	4	70	22498	2983583	1.766	0.771	3.59	2.945	4.644	2.946	0.031	1.67514796	0.5687171
Infliximab	Band neutrophil percentage increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	35	22499	2983618	2.136	0.828	4.747	6.437	11.447	6.439	0.001	1.6280008	0.75893492
Infliximab	Barotrauma	Atmospheric pressure injuries	Injuries by physical agents	Inj&P	1968-2006	1	12	22501	2983641	1.201	0.277	3.764	7.414	4.509	7.414	0.034	0.85518395	0.18315454
Infliximab	Barretts oesophagus	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	1	304	22501	2983349	0.286	0.066	0.895	0.236	2.47	0.236	0.116	-0.7260092	-1.2517635
Infliximab	Bartholins abscess	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	9	22501	2983644	1.195	0.276	3.744	7.495	4.307	7.495	0.038	0.88501574	0.17814619
Infliximab	Bartholins cyst	Vulvovaginal cysts and neoplasms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	4	13	22498	2983640	3.352	1.408	7.549	23.374	45.905	23.38	1.241e-11	2.13827238	1.20955718
Infliximab	Bartholinitis	Vaginal and vulval infections and inflammations	Female reproductive tract infections and inflammations	Repro	1968-2006	1	6	22501	2983647	1.197	0.276	3.749	6.391	4.369	6.391	0.037	0.91547736	0.17981843
Infliximab	Basal cell carcinoma	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	280	466	22222	2983187	18.451	16.705	20.337	38.641	4777.889	39.18	0	5.40436882	2.91511857
Infliximab	Basedows disease	Thyroid hyperfunction disorders	Thyroid gland disorders	Endo	1968-2006	2	154	22500	2983499	0.645	0.209	1.616	0.715	0.224	0.715	0.636	0.45787792	-0.438505
Infliximab	Basilar artery occlusion	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	1	20	22501	2983633	0.985	0.228	3.075	2.43	0.756	2.43	0.384	0.77852244	-0.0151136
Infliximab	Basophil count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	75	22501	2983578	0.635	0.147	1.982	0.775	0.062	0.775	0.803	0.33938578	-0.4541303
Infliximab	Basosquamous carcinoma	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	1	1	22501	2983652	1.328	0.305	4.193	26.341	19.174	26.341	0.00001193	0.967721	0.28367405
Infliximab	Bedridden	Disability issues	Lifestyle issues	SocCi	1968-2006	6	584	22496	2983069	0.54	0.273	0.984	0.543	2.272	0.542	0.132	0.35891713	-0.6161861
Infliximab	Behcets syndrome	Vasculitides	Immune disorders NEC	Immun	1968-2006	8	50	22494	2983603	3.904	2.137	6.762	8.818	44.533	8.821	2.501e-11	2.63886477	1.36200167
Infliximab	Bence Jones protein urine present	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	14	22501	2983639	1.076	0.249	3.362	3.594	1.629	3.594	0.202	0.83563334	0.07325046
Infliximab	Bence Jones proteinuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	1	27	22501	2983626	1.105	0.256	3.456	3.858	2.049	3.858	0.152	0.71463025	0.09984533
Infliximab	Benign breast neoplasm	Breast and nipple neoplasms benign	Breast neoplasms benign (incl nipple)	Neopl	1968-2006	4	170	22498	2983483	0.945	0.412	1.919	1.096	0.033	1.096	0.855	1.10784008	-0.0565704
Infliximab	Benign colonic neoplasm	Lower gastrointestinal neoplasms benign	Gastrointestinal neoplasms benign	Neopl	1968-2006	1	29	22501	2983624	0.995	0.23	3.109	2.47	0.832	2.47	0.362	0.69688322	-0.0050125
Infliximab	Benign gastrointestinal neoplasm	Gastrointestinal neoplasms benign NEC	Gastrointestinal neoplasms benign	Neopl	1968-2006	1	19	22501	2983634	1.102	0.255	3.446	4.122	2.013	4.122	0.156	0.78788532	0.09712671
Infliximab	Benign intracranial hypertension	Increased intracranial pressure disorders	Increased intracranial pressure and hydrocephalus	Nerv	1968-2006	2	559	22500	2983094	0.25	0.081	0.626	0.221	5.503	0.221	0.019	-0.8044525	-1.3862944
Infliximab	Benign lung neoplasm	Respiratory tract and pleural neoplasms benign NEC	Respiratory and mediastinal neoplasms benign (excl mesotheliomas)	Neopl	1968-2006	2	38	22500	2983615	1.505	0.488	3.78	3.828	3.771	3.828	0.052	1.19624438	0.4087929
Infliximab	Benign neoplasm	Neoplasms benign site unspecified NEC	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	7	68	22495	2983585	3.689	1.94	6.595	8.269	39.367	8.271	3.513e-10	2.34628704	1.30535542
Infliximab	Benign ovarian tumour	Ovarian neoplasms benign	Reproductive neoplasms female benign	Neopl	1968-2006	1	51	22501	2983602	0.754	0.175	2.355	1.113	0.011	1.113	0.917	0.51484364	-0.2823629
Infliximab	Benign prostatic hyperplasia	Prostatic neoplasms and hypertrophy	Prostatic disorders (excl infections and inflammations)	Repro	1968-2006	13	1022	22489	2982631	1.112	0.697	1.702	1.183	0.359	1.183	0.549	0.66718458	0.1061602
Infliximab	Benign salivary gland neoplasm	Gastrointestinal neoplasms benign NEC	Gastrointestinal neoplasms benign	Neopl	1968-2006	2	6	22500	2983647	2.046	0.654	5.26	25.025	24.846	25.025	6.209e-7	1.4902144	0.71588667
Infliximab	Beta 2 microglobulin increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	3	61	22499	2983592	1.668	0.648	3.691	3.106	4.134	3.106	0.042	1.42444967	0.5116253
Infliximab	Beta haemolytic streptococcal infection	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	11	195	22491	2983458	2.176	1.31	3.446	2.754	11.441	2.755	0.001	2.22807808	0.77748833
Infliximab	Bezoar	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	1	175	22501	2983478	0.776	0.18	2.423	1.19	0.029	1.19	0.866	-0.2234399	-0.2536028
Infliximab	Bicytopenia	Marrow depression and hypoplastic anaemias	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	2	39	22500	2983614	1.461	0.473	3.669	3.466	3.222	3.467	0.073	1.18795706	0.37912113
Infliximab	Bifidobacterium infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.368	0.312	4.344	1085.895	76.698	1093.547	1.992e-18	0.97840063	0.31334982
Infliximab	Bile duct cancer	Bile duct neoplasms malignant	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	12	206	22490	2983447	3.147	1.934	4.901	4.479	29.736	4.481	4.95e-8	2.29345055	1.14644962
Infliximab	Bile duct obstruction	Obstructive bile duct disorders (excl neoplasms)	Bile duct disorders	Hepat	1968-2006	10	468	22492	2983185	1.49	0.875	2.407	1.719	2.843	1.719	0.092	1.25365517	0.39877612
Infliximab	Bile duct stenosis	Structural and other bile duct disorders	Bile duct disorders	Hepat	1968-2006	6	156	22496	2983497	1.709	0.862	3.112	2.305	4.147	2.306	0.042	1.65068336	0.5359084
Infliximab	Bile duct stent insertion	Biliary tract and gallbladder therapeutic procedures	Hepatobiliary therapeutic procedures	Surg	1968-2006	1	8	22501	2983645	1.147	0.265	3.588	5.1	2.871	5.101	0.09	0.89509832	0.13714984
Infliximab	Bile duct stone	Obstructive bile duct disorders (excl neoplasms)	Bile duct disorders	Hepat	1968-2006	5	352	22497	2983301	0.907	0.43	1.732	1.009	0	1.009	0.984	0.69728652	-0.0976128
Infliximab	Biliary cirrhosis primary	Hepatic fibrosis and cirrhosis	Hepatic and hepatobiliary disorders	Hepat	1968-2006	2	115	22500	2983538	0.834	0.27	2.091	1.056	0.006	1.056	0.94	0.66657562	-0.1815219
Infliximab	Biliary colic	Bile duct infections and inflammations	Bile duct disorders	Hepat	1968-2006	2	304	22500	2983349	0.66	0.214	1.654	0.74	0.182	0.74	0.67	-0.1443324	-0.4155154
Infliximab	Biliary dilatation	Structural and other bile duct disorders	Bile duct disorders	Hepat	1968-2006	3	175	22499	2983478	0.867	0.337	1.917	1.024	0.002	1.024	0.967	0.76726977	-0.1427163
Infliximab	Biliary dyskinesia	Gallbladder disorders NEC	Gallbladder disorders	Hepat	1968-2006	1	33	22501	2983620	0.948	0.219	2.959	2.108	0.529	2.108	0.467	0.66203088	-0.0534008
Infliximab	Biliary neoplasm	Hepatobiliary neoplasms malignancy unspecified	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	1	71	22501	2983582	0.658	0.152	2.055	0.834	0.033	0.834	0.857	0.36718681	-0.4185503
Infliximab	Biliary tract disorder	Structural and other bile duct disorders	Bile duct disorders	Hepat	1968-2006	10	558	22492	2983095	1.196	0.702	1.931	1.315	0.725	1.315	0.395	1.05554998	0.17898266
Infliximab	Biliary tract infection	Hepatobiliary and spleen infections	Infections - pathogen class unspecified	Infec	1968-2006	1	35	22501	2983618	0.892	0.206	2.786	1.708	0.286	1.708	0.593	0.64491541	-0.1142891
Infliximab	Bilirubin conjugated increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	2	526	22500	2983127	0.248	0.08	0.622	0.217	5.569	0.217	0.018	-0.7342128	-1.3943265
Infliximab	Biopsy	Histopathology procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	1	33	22501	2983620	0.911	0.211	2.845	1.821	0.36	1.821	0.549	0.66203088	-0.0932124
Infliximab	Biopsy artery	Vascular and lymphatic histopathology procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	0	22501	2983653	1.364	0.311	4.328	1084.324	71.361	1091.976	2.975e-17	0.97840063	0.31042156
Infliximab	Biopsy artery abnormal	Vascular and lymphatic histopathology procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	0	22501	2983653	1.343	0.308	4.249	1074.85	50.194	1082.447	1.393e-12	0.97840063	0.29490592
Infliximab	Biopsy artery normal	Vascular and lymphatic histopathology procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	0	22501	2983653	1.355	0.31	4.295	1080.439	60.862	1088.06	6.122e-15	0.97840063	0.30380145
Infliximab	Biopsy blood vessel abnormal	Vascular and lymphatic histopathology procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	1	22501	2983652	1.376	0.313	4.376	101.639	50.486	101.639	1.2e-12	0.967721	0.31918074
Infliximab	Biopsy bone marrow abnormal	Bone marrow and immune tissue analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	8	481	22494	2983172	1.102	0.608	1.87	1.218	0.302	1.218	0.583	0.93842512	0.09712671
Infliximab	Biopsy breast	Reproductive organ and breast histopathology procedures	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	14	22501	2983639	1.103	0.255	3.448	4.008	2.02	4.009	0.155	0.83563334	0.09803374
Infliximab	Biopsy breast abnormal	Reproductive organ and breast histopathology procedures	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	32	22501	2983621	0.914	0.212	2.855	1.854	0.373	1.855	0.541	0.67066536	-0.0899247
Infliximab	Biopsy breast normal	Reproductive organ and breast histopathology procedures	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	0	22501	2983653	1.371	0.313	4.358	1087.21	81.81	1094.875	1.498e-19	0.97840063	0.3155404
Infliximab	Biopsy liver abnormal	Hepatobiliary histopathology procedures	Hepatobiliary investigations	Inv	1968-2006	6	307	22496	2983346	1.286	0.649	2.342	1.539	1.093	1.539	0.296	1.05526587	0.25153663
Infliximab	Biopsy lung	Respiratory tract and thoracic histopathology procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	6	22501	2983647	1.245	0.287	3.906	12.029	6.798	12.029	0.009	0.91547736	0.21913553
Infliximab	Biopsy lung abnormal	Respiratory tract and thoracic histopathology procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	8	82	22494	2983571	3.652	2.006	6.271	7.632	37.807	7.635	7.81e-10	2.41602187	1.29527496
Infliximab	Biopsy lymph gland abnormal	Bone marrow and immune tissue analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	32	22500	2983621	1.608	0.521	4.042	4.79	5.342	4.79	0.021	1.24699348	0.47499117
Infliximab	Biopsy peripheral nerve abnormal	Peripheral nervous system histopathology procedures	Neurological and special sense investigations	Inv	1968-2006	1	14	22501	2983639	1.198	0.277	3.753	7.614	4.404	7.614	0.036	0.83563334	0.1806535
Infliximab	Biopsy prostate abnormal	Reproductive organ and breast histopathology procedures	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	4	22501	2983649	1.294	0.298	4.073	18.527	11.75	18.527	0.001	0.93614837	0.2577382
Infliximab	Biopsy site unspecified abnormal	Histopathology procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	3	85	22499	2983568	1.49	0.579	3.295	2.491	2.525	2.492	0.112	1.25905943	0.39877612
Infliximab	Biopsy skin abnormal	Skin histopathology procedures	Skin investigations	Inv	1968-2006	5	226	22497	2983427	1.405	0.666	2.685	1.803	1.752	1.804	0.186	1.12558478	0.3400373
Infliximab	Bipolar I disorder	Bipolar disorders	Manic and bipolar mood disorders and disturbances	Psych	1968-2006	4	582	22498	2983071	0.636	0.278	1.292	0.664	0.662	0.664	0.416	-0.1185113	-0.4525567
Infliximab	Bipolar disorder	Bipolar disorders	Manic and bipolar mood disorders and disturbances	Psych	1968-2006	3	968	22499	2982685	0.194	0.075	0.43	0.172	11.722	0.172	0.001	-1.0588862	-1.6398971
Infliximab	Bite	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	139	22501	2983514	0.574	0.133	1.792	0.652	0.188	0.652	0.664	-0.0450823	-0.5551259
Infliximab	Bladder cancer	Bladder neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	54	815	22448	2982838	5.393	4.289	6.717	6.668	229.247	6.689	0	2.86232279	1.68510182
Infliximab	Bladder cancer recurrent	Bladder neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	3	44	22499	2983609	1.85	0.718	4.097	4.145	6.336	4.145	0.012	1.55424615	0.61518564
Infliximab	Bladder cancer stage II	Bladder neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	14	22501	2983639	1.241	0.286	3.892	9.819	6.449	9.825	0.011	0.83563334	0.21591751
Infliximab	Bladder cancer stage III	Bladder neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.308	0.301	4.122	25.735	14.132	25.735	0.0001704	0.946596	0.26849925
Infliximab	Bladder disorder	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	15	1231	22487	2982422	0.888	0.575	1.323	0.916	0.112	0.916	0.738	0.62025883	-0.1187835
Infliximab	Bladder diverticulum	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	2	20	22500	2983633	1.712	0.554	4.311	6.27	7.561	6.273	0.006	1.3541825	0.53766228
Infliximab	Bladder hypertrophy	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	1	15	22501	2983638	1.146	0.265	3.584	5.017	2.825	5.018	0.093	0.82595649	0.13627762
Infliximab	Bladder mass	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	3	23	22499	2983630	2.261	0.875	5.039	7.592	14.69	7.593	0.0001267	1.73259846	0.81580719
Infliximab	Bladder neoplasm	Urinary tract neoplasms unspecified malignancy NEC	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	9	170	22493	2983483	3.325	1.894	5.517	5.749	30.443	5.753	3.438e-8	2.08457643	1.20146967
Infliximab	Bladder obstruction	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	2	81	22500	2983572	1.117	0.362	2.801	1.782	0.668	1.782	0.414	0.8769495	0.11064652
Infliximab	Bladder operation	Bladder therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	2	62	22500	2983591	1.078	0.35	2.704	1.683	0.516	1.683	0.473	1.00941201	0.07510747
Infliximab	Bladder pain	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	1	340	22501	2983313	0.291	0.067	0.909	0.243	2.388	0.243	0.122	-0.8398341	-1.234432
Infliximab	Bladder perforation	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	1	17	22501	2983636	1.069	0.247	3.341	3.346	1.542	3.346	0.214	0.80679534	0.06672363
Infliximab	Bladder prolapse	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	2	72	22500	2983581	0.986	0.32	2.473	1.416	0.229	1.416	0.632	0.93818202	-0.0140989
Infliximab	Bladder spasm	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	2	152	22500	2983501	0.63	0.204	1.58	0.692	0.27	0.692	0.603	0.46787698	-0.4620355
Infliximab	Bladder tamponade	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	1	12	22501	2983641	1.262	0.291	3.963	10.374	7.988	10.379	0.005	0.85518395	0.23269776
Infliximab	Bladder transitional cell carcinoma	Bladder neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	5	22501	2983648	1.265	0.292	3.975	10.634	8.458	10.638	0.004	0.92577585	0.23507212
Infliximab	Blast cells present	Haematological analyses NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	1	38	22501	2983615	0.907	0.21	2.831	1.795	0.34	1.795	0.56	0.61961696	-0.0976128
Infliximab	Blast crisis in myelogenous leukaemia	Leukaemias myeloid NEC	Leukaemias	Neopl	1968-2006	1	90	22501	2983563	0.51	0.118	1.592	0.53	0.41	0.53	0.522	0.23965713	-0.6733446
Infliximab	Blast injury	Atmospheric pressure injuries	Injuries by physical agents	Inj&P	1968-2006	1	2	22501	2983651	1.355	0.31	4.297	53.676	31.308	53.676	2.202e-8	0.95711984	0.30380145
Infliximab	Blastomycosis	Blastomyces infections	Fungal infectious disorders	Infec	1968-2006	6	14	22496	2983639	6.416	2.477	22.716	32.863	100.573	32.863	1.141e-23	2.59524057	1.85879487
Infliximab	Bleeding time prolonged	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	1263	22500	2982390	0.472	0.153	1.184	0.468	1.177	0.468	0.278	-1.814527	-0.7507763
Infliximab	Bleeding varicose vein	Varicose veins non-site specific	Venous varices	Vasc	1968-2006	3	40	22499	2983613	2.122	0.823	4.715	5.971	11.113	5.973	0.001	1.58656148	0.75235904
Infliximab	Blighted ovum	Abortion related conditions and complications	Abortions and stillbirth	Preg	1968-2006	3	138	22499	2983515	0.954	0.371	2.11	1.177	0.077	1.177	0.782	0.94965418	-0.0470916
Infliximab	Blindness	Blindness (excl colour blindness)	Vision disorders	Eye	1968-2006	49	5584	22453	2978069	0.858	0.675	1.078	0.863	1.042	0.863	0.307	0.1985332	-0.1531512
Infliximab	Blindness transient	Blindness (excl colour blindness)	Vision disorders	Eye	1968-2006	16	980	22486	2982673	1.027	0.674	1.513	1.073	0.076	1.073	0.783	0.99628202	0.02664193
Infliximab	Blindness unilateral	Blindness (excl colour blindness)	Vision disorders	Eye	1968-2006	21	1807	22481	2981846	0.679	0.47	0.954	0.682	3.071	0.682	0.08	0.57162946	-0.3871342
Infliximab	Blister	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	51	4297	22451	2979356	0.867	0.686	1.085	0.873	0.929	0.873	0.335	0.61944729	-0.1427163
Infliximab	Blood albumin	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	8	79	22494	2983574	2.477	1.367	4.209	3.672	14.266	3.679	0.0001587	2.43551111	0.90704815
Infliximab	Blood albumin abnormal	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	4	77	22498	2983576	1.588	0.693	3.228	2.425	3.074	2.425	0.08	1.62729989	0.46247536
Infliximab	Blood albumin decreased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	35	2041	22467	2981612	1.115	0.839	1.457	1.143	0.608	1.143	0.436	1.11025455	0.1088544
Infliximab	Blood albumin increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	3	296	22499	2983357	0.678	0.263	1.499	0.735	0.281	0.735	0.596	0.29386677	-0.388608
Infliximab	Blood alcohol increased	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	2	438	22500	2983215	0.331	0.107	0.83	0.304	3.15	0.304	0.076	-0.5282545	-1.1056369
Infliximab	Blood alkaline phosphatase	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	10	155	22492	2983498	2.123	1.246	3.429	2.718	10.182	2.723	0.001	2.28819156	0.75283018
Infliximab	Blood alkaline phosphatase abnormal	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	2	86	22500	2983567	0.784	0.254	1.966	0.956	0.004	0.956	0.95	0.84402174	-0.2433463
Infliximab	Blood alkaline phosphatase decreased	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	1	95	22501	2983558	0.606	0.14	1.892	0.71	0.113	0.71	0.737	0.20788933	-0.5008753
Infliximab	Blood alkaline phosphatase increased	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	84	13904	22418	2969749	0.657	0.547	0.782	0.653	15.361	0.651	0.00008879	-0.3320795	-0.4200713
Infliximab	Blood amylase	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	1	21	22501	2983632	0.939	0.217	2.932	2.013	0.488	2.013	0.485	0.76921993	-0.0629398
Infliximab	Blood amylase abnormal	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	1	12	22501	2983641	1.068	0.247	3.337	3.463	1.531	3.464	0.216	0.85518395	0.06578774
Infliximab	Blood amylase decreased	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	1	52	22501	2983601	0.846	0.196	2.64	1.469	0.147	1.469	0.702	0.50709068	-0.1672359
Infliximab	Blood amylase increased	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	8	4067	22494	2979586	0.337	0.186	0.573	0.328	10.978	0.328	0.001	-1.8202819	-1.0876723
Infliximab	Blood beta-D-glucan decreased	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	1	22501	2983652	1.385	0.315	4.416	193.682	67.01	193.682	2.702e-16	0.967721	0.32570014
Infliximab	Blood beta-D-glucan increased	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	86	22500	2983567	0.979	0.317	2.454	1.388	0.21	1.388	0.647	0.84402174	-0.0212236
Infliximab	Blood bicarbonate	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	5	50	22497	2983603	2.245	1.064	4.294	4.015	10.201	4.021	0.001	2.07667171	0.80870552
Infliximab	Blood bicarbonate decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	943	22501	2982710	0.1	0.023	0.314	0.069	12.266	0.069	0.0004612	-2.0231715	-2.3025851
Infliximab	Blood bicarbonate increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	2	218	22500	2983435	0.566	0.183	1.419	0.597	0.537	0.597	0.464	0.16978604	-0.5691612
Infliximab	Blood bilirubin	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	3	120	22499	2983533	0.838	0.326	1.852	0.976	0.002	0.976	0.967	1.04747507	-0.1767372
Infliximab	Blood bilirubin decreased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	2	39	22500	2983614	1.338	0.434	3.357	2.709	2.027	2.709	0.155	1.18795706	0.29117596
Infliximab	Blood bilirubin increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	43	8581	22459	2975072	0.397	0.308	0.506	0.392	40.586	0.391	1.881e-10	-0.5901588	-0.923819
Infliximab	Blood blister	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	3	175	22499	2983478	0.772	0.3	1.707	0.872	0.055	0.872	0.815	0.76726977	-0.2587707
Infliximab	Blood calcium	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	79	22501	2983574	0.495	0.114	1.544	0.506	0.48	0.505	0.488	0.31211031	-0.7031975
Infliximab	Blood calcium abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	4	102	22498	2983551	1.331	0.581	2.705	1.795	1.348	1.795	0.246	1.46830672	0.28593054
Infliximab	Blood calcium decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	16	1315	22486	2982338	0.699	0.459	1.03	0.707	1.915	0.706	0.166	0.62142407	-0.3581045
Infliximab	Blood calcium increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	9	859	22493	2982794	0.614	0.35	1.014	0.622	2.057	0.622	0.152	0.40431244	-0.4877604
Infliximab	Blood cannabinoids increased	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	1	14	22501	2983639	1.171	0.271	3.666	5.813	3.478	5.815	0.062	0.83563334	0.15785808
Infliximab	Blood chloride	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	7	89	22495	2983564	2.048	1.086	3.59	2.895	7.961	2.9	0.005	2.20789056	0.71686371
Infliximab	Blood chloride abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	32	22501	2983621	0.79	0.183	2.465	1.237	0.044	1.237	0.833	0.67066536	-0.2357223
Infliximab	Blood chloride decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	13	982	22489	2982671	0.766	0.48	1.172	0.782	0.768	0.782	0.381	0.71745105	-0.2665731
Infliximab	Blood chloride increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	2	497	22500	2983156	0.283	0.092	0.708	0.252	4.374	0.252	0.036	-0.6695327	-1.2623084
Infliximab	Blood cholesterol	Cholesterol analyses	Lipid analyses	Inv	1968-2006	1	87	22501	2983566	0.529	0.122	1.65	0.559	0.335	0.559	0.563	0.25905904	-0.6367668
Infliximab	Blood cholesterol increased	Cholesterol analyses	Lipid analyses	Inv	1968-2006	30	5695	22472	2977958	0.358	0.263	0.477	0.351	35.793	0.35	2.194e-9	-0.5140153	-1.0272223
Infliximab	Blood cholinesterase decreased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	2	149	22500	2983504	0.933	0.302	2.34	1.274	0.115	1.274	0.735	0.48300669	-0.0693501
Infliximab	Blood cholinesterase increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	61	22501	2983592	0.861	0.199	2.687	1.537	0.186	1.537	0.666	0.43912725	-0.1496608
Infliximab	Blood corticotrophin abnormal	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	16	22501	2983637	1.104	0.255	3.451	3.8	2.035	3.8	0.154	0.81634411	0.09893995
Infliximab	Blood corticotrophin increased	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	32	22501	2983621	1.017	0.235	3.176	2.625	0.999	2.625	0.318	0.67066536	0.01685712
Infliximab	Blood cortisol decreased	Adrenal cortex tests	Endocrine investigations (incl sex hormones)	Inv	1968-2006	2	206	22500	2983447	0.674	0.219	1.691	0.761	0.145	0.761	0.703	0.21960282	-0.3945252
Infliximab	Blood count abnormal	Blood counts NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	1	101	22501	2983552	0.558	0.129	1.742	0.615	0.235	0.615	0.628	0.17066877	-0.5833963
Infliximab	Blood creatine decreased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	36	22501	2983617	0.977	0.226	3.051	2.351	0.701	2.351	0.402	0.63643321	-0.0232686
Infliximab	Blood creatine increased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	10	1216	22492	2982437	0.695	0.408	1.122	0.709	1.166	0.709	0.28	0.10076577	-0.3638434
Infliximab	Blood creatine phosphokinase	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	4	125	22498	2983528	1.081	0.472	2.196	1.321	0.3	1.322	0.584	1.33605415	0.07788654
Infliximab	Blood creatine phosphokinase MB	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	3	49	22499	2983604	1.564	0.607	3.459	2.774	3.151	2.776	0.076	1.51484391	0.44724664
Infliximab	Blood creatine phosphokinase MB increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	5	855	22497	2982798	0.451	0.214	0.862	0.445	3.406	0.444	0.065	-0.3210815	-0.7962879
Infliximab	Blood creatine phosphokinase abnormal	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	2	85	22500	2983568	0.852	0.276	2.135	1.092	0.015	1.092	0.903	0.85054745	-0.1601688
Infliximab	Blood creatine phosphokinase increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	54	16042	22448	2967611	0.352	0.28	0.438	0.346	66.647	0.344	3.247e-16	-1.1618735	-1.0441241
Infliximab	Blood creatinine	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	16	255	22486	2983398	2.116	1.389	3.116	2.485	13.353	2.494	0.000258	2.4778858	0.74952751
Infliximab	Blood creatinine abnormal	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	6	300	22496	2983353	0.937	0.473	1.706	1.031	0.005	1.031	0.942	1.07806135	-0.065072
Infliximab	Blood creatinine decreased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	9	398	22493	2983255	1.319	0.753	2.181	1.495	1.424	1.495	0.233	1.29421386	0.27687387
Infliximab	Blood creatinine increased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	66	23714	22436	2959939	0.404	0.329	0.492	0.398	60.015	0.396	9.413e-15	-1.4400825	-0.9063404
Infliximab	Blood culture positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	53	1606	22449	2982047	2.106	1.673	2.623	2.246	34.768	2.25	3.715e-9	1.99715899	0.74479041
Infliximab	Blood disorder	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	18	1102	22484	2982551	1.329	0.894	1.918	1.419	2.157	1.42	0.142	1.00642197	0.28442678
Infliximab	Blood electrolytes abnormal	Water and electrolyte analyses NEC	Water, electrolyte and mineral investigations	Inv	1968-2006	3	262	22499	2983391	0.631	0.245	1.394	0.668	0.482	0.668	0.488	0.4119765	-0.4604494
Infliximab	Blood fibrinogen decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	4	485	22498	2983168	0.898	0.392	1.825	1.026	0.003	1.026	0.96	0.09042669	-0.1075852
Infliximab	Blood fibrinogen increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	4	473	22498	2983180	0.589	0.257	1.197	0.606	1.001	0.605	0.317	0.11851069	-0.5293291
Infliximab	Blood folate decreased	Vitamin analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	96	22501	2983557	0.55	0.127	1.716	0.6	0.262	0.6	0.609	0.20161885	-0.597837
Infliximab	Blood folate increased	Vitamin analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	24	22501	2983629	0.962	0.223	3.005	2.144	0.615	2.144	0.433	0.74166694	-0.0387408
Infliximab	Blood gases abnormal	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	317	22501	2983336	0.338	0.078	1.054	0.288	1.712	0.288	0.191	-0.7681556	-1.0847094
Infliximab	Blood glucagon abnormal	Gastrointestinal, pancreatic and APUD hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	1	22501	2983652	1.358	0.31	4.308	80.876	33.264	80.876	8.046e-9	0.967721	0.30601303
Infliximab	Blood glucose	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	12	211	22490	2983442	1.924	1.183	2.993	2.306	8.363	2.31	0.004	2.27307626	0.65440635
Infliximab	Blood glucose abnormal	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	4	689	22498	2982964	0.367	0.16	0.747	0.354	4.689	0.354	0.03	-0.3185584	-1.0023934
Infliximab	Blood glucose decreased	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	18	5620	22484	2978033	0.206	0.139	0.298	0.199	57.723	0.198	3.017e-14	-1.1986629	-1.5798791
Infliximab	Blood glucose fluctuation	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	2	1282	22500	2982371	0.099	0.032	0.25	0.081	20.726	0.081	0.0000053	-1.8340033	-2.3126354
Infliximab	Blood glucose increased	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	73	16684	22429	2966969	0.271	0.223	0.327	0.265	149.48	0.263	2.253e-34	-0.7916852	-1.3056365
Infliximab	Blood gonadotrophin increased	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	45	22501	2983608	1.132	0.262	3.542	4.718	2.542	4.718	0.111	0.56225713	0.12398598
Infliximab	Blood homocysteine increased	Metabolism tests NEC	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	85	22501	2983568	0.607	0.14	1.896	0.713	0.111	0.713	0.739	0.27214012	-0.4992265
Infliximab	Blood immunoglobulin A	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	5	22501	2983648	1.318	0.303	4.158	30.204	16.229	30.204	0.00005613	0.92577585	0.27611544
Infliximab	Blood immunoglobulin A increased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	155	22501	2983498	0.494	0.114	1.541	0.505	0.481	0.505	0.488	-0.1270848	-0.7052198
Infliximab	Blood immunoglobulin E increased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	2	352	22500	2983301	0.421	0.136	1.056	0.407	1.706	0.407	0.192	-0.2938639	-0.8651224
Infliximab	Blood immunoglobulin G decreased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	2	144	22500	2983509	0.772	0.25	1.935	0.934	0.009	0.934	0.923	0.50858084	-0.2587707
Infliximab	Blood immunoglobulin G increased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	10	398	22492	2983255	1.496	0.878	2.416	1.724	2.898	1.725	0.089	1.42905102	0.40279488
Infliximab	Blood immunoglobulin M	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	10	22501	2983643	1.169	0.27	3.66	5.91	3.456	5.91	0.063	0.87500312	0.15614868
Infliximab	Blood immunoglobulin M abnormal	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	5	22501	2983648	1.287	0.296	4.049	22.009	10.799	22.009	0.001	0.92577585	0.25231393
Infliximab	Blood immunoglobulin M decreased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	82	22501	2983571	0.687	0.159	2.143	0.907	0.009	0.907	0.923	0.29198681	-0.375421
Infliximab	Blood immunoglobulin M increased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	9	164	22493	2983489	2.912	1.661	4.821	4.464	22.146	4.465	2.527e-6	2.11253982	1.06884013
Infliximab	Blood insulin abnormal	Gastrointestinal, pancreatic and APUD hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	12	22501	2983641	1.22	0.282	3.824	7.301	5.329	7.301	0.021	0.85518395	0.19885086
Infliximab	Blood iron	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	6	22501	2983647	1.158	0.268	3.624	5.747	3.164	5.748	0.075	0.91547736	0.14669438
Infliximab	Blood iron abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	35	22501	2983618	0.889	0.206	2.775	1.68	0.275	1.68	0.6	0.64491541	-0.117658
Infliximab	Blood iron decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	5	480	22497	2983173	0.694	0.329	1.325	0.727	0.495	0.727	0.482	0.36276222	-0.3652833
Infliximab	Blood iron increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	4	420	22498	2983233	1.028	0.449	2.089	1.23	0.167	1.23	0.683	0.24953439	0.02761517
Infliximab	Blood lactate dehydrogenase	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	3	73	22499	2983580	1.193	0.463	2.637	1.667	0.771	1.668	0.38	1.33938614	0.17647114
Infliximab	Blood lactate dehydrogenase abnormal	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	2	60	22500	2983593	1.044	0.338	2.617	1.571	0.395	1.571	0.53	1.0240899	0.04305949
Infliximab	Blood lactate dehydrogenase decreased	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	3	69	22499	2983584	1.558	0.605	3.446	2.726	3.088	2.726	0.079	1.36718715	0.44340295
Infliximab	Blood lactate dehydrogenase increased	Tissue enzyme analyses NEC	Enzyme investigations NEC	Inv	1968-2006	84	9065	22418	2974588	0.949	0.791	1.131	0.954	0.183	0.954	0.669	0.27557214	-0.0523465
Infliximab	Blood lactic acid	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	13	22501	2983640	1.015	0.235	3.171	2.677	0.993	2.678	0.319	0.84537553	0.01488861
Infliximab	Blood magnesium	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	3	45	22499	2983608	1.6	0.621	3.539	2.897	3.483	2.898	0.062	1.54627915	0.47000363
Infliximab	Blood magnesium abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	3	36	22499	2983617	1.841	0.715	4.078	4.016	6.244	4.016	0.012	1.61961718	0.6103089
Infliximab	Blood magnesium decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	12	1396	22490	2982257	0.872	0.536	1.356	0.905	0.116	0.905	0.734	0.16043995	-0.1369659
Infliximab	Blood magnesium increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	4	188	22498	2983465	1.051	0.459	2.135	1.268	0.22	1.268	0.639	1.02578498	0.04974209
Infliximab	Blood osmolarity decreased	Water and electrolyte analyses NEC	Water, electrolyte and mineral investigations	Inv	1968-2006	2	230	22500	2983423	0.57	0.185	1.429	0.599	0.518	0.599	0.472	0.12163181	-0.5621189
Infliximab	Blood pH decreased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	6	1316	22496	2982337	0.346	0.175	0.63	0.334	7.892	0.333	0.005	-0.6497911	-1.0613165
Infliximab	Blood pH increased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	11	408	22491	2983245	1.608	0.968	2.545	1.849	4.158	1.85	0.041	1.5255689	0.47499117
Infliximab	Blood parathyroid hormone increased	Parathyroid analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	241	22501	2983412	0.273	0.063	0.854	0.219	2.724	0.219	0.099	-0.5022673	-1.2982835
Infliximab	Blood phosphorus abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	19	22501	2983634	0.941	0.218	2.939	2.029	0.501	2.029	0.479	0.78788532	-0.0608121
Infliximab	Blood phosphorus decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	2	309	22500	2983344	0.387	0.125	0.97	0.367	2.166	0.367	0.141	-0.1606516	-0.9493306
Infliximab	Blood phosphorus increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	2	359	22500	2983294	0.36	0.117	0.904	0.341	2.588	0.341	0.108	-0.3144316	-1.0216512
Infliximab	Blood potassium	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	14	217	22488	2983436	2.062	1.314	3.112	2.466	11.347	2.473	0.001	2.44751564	0.72367639
Infliximab	Blood potassium abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	4	184	22498	2983469	0.924	0.403	1.877	1.065	0.015	1.065	0.901	1.04362046	-0.0790432
Infliximab	Blood potassium decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	52	3379	22450	2980274	0.856	0.679	1.069	0.861	1.147	0.86	0.284	0.97764637	-0.1554849
Infliximab	Blood potassium increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	17	2710	22485	2980943	0.407	0.271	0.593	0.4	15.136	0.399	0.0001	-0.2626018	-0.8989421
Infliximab	Blood potassium normal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	0	22501	2983653	1.371	0.313	4.358	1087.21	81.81	1094.875	1.498e-19	0.97840063	0.3155404
Infliximab	Blood pressure	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	242	22499	2983411	0.529	0.206	1.169	0.538	1.178	0.538	0.278	0.48625436	-0.6367668
Infliximab	Blood pressure abnormal	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	8	649	22494	2983004	0.698	0.385	1.185	0.718	0.872	0.718	0.351	0.5936993	-0.3595362
Infliximab	Blood pressure decreased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	256	9554	22246	2974099	1.68	1.514	1.859	1.717	74.28	1.726	6.778e-18	1.77232813	0.51879379
Infliximab	Blood pressure diastolic abnormal	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	14	22501	2983639	1.181	0.273	3.698	5.831	3.812	5.831	0.051	0.83563334	0.16636154
Infliximab	Blood pressure diastolic decreased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	6	889	22496	2982764	0.432	0.218	0.786	0.423	4.627	0.423	0.031	-0.1486508	-0.8393297
Infliximab	Blood pressure diastolic increased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	8	405	22494	2983248	1.119	0.618	1.9	1.238	0.363	1.239	0.547	1.12628343	0.11243543
Infliximab	Blood pressure fluctuation	Blood pressure disorders NEC	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	13	1189	22489	2982464	0.731	0.458	1.119	0.745	1.12	0.745	0.29	0.47439634	-0.3133418
Infliximab	Blood pressure immeasurable	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	365	22499	2983288	0.444	0.173	0.982	0.44	2.152	0.44	0.142	0.08032757	-0.8119307
Infliximab	Blood pressure inadequately controlled	Blood pressure disorders NEC	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	2	639	22500	2983014	0.208	0.067	0.521	0.179	7.488	0.179	0.006	-0.9617612	-1.5702172
Infliximab	Blood pressure increased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	224	14619	22278	2969034	0.928	0.831	1.035	0.929	1.203	0.928	0.273	0.9871562	-0.0747235
Infliximab	Blood pressure systolic decreased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	14	1081	22488	2982572	0.907	0.578	1.368	0.94	0.053	0.94	0.818	0.69445731	-0.0976128
Infliximab	Blood pressure systolic increased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	35	2098	22467	2981555	1.029	0.775	1.345	1.05	0.081	1.05	0.775	1.07348233	0.02858746
Infliximab	Blood product transfusion	Blood and blood product treatment	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	2	20	22500	2983633	1.916	0.617	4.862	11.443	15.244	11.443	0.00009448	1.3541825	0.65023968
Infliximab	Blood prolactin increased	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	3	1572	22499	2982081	0.398	0.155	0.88	0.384	2.931	0.384	0.087	-1.6884712	-0.9213033
Infliximab	Blood sodium	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	8	164	22494	2983489	1.501	0.828	2.548	1.792	2.688	1.794	0.101	1.96525015	0.40613155
Infliximab	Blood sodium abnormal	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	105	22501	2983548	0.477	0.11	1.489	0.474	0.567	0.474	0.451	0.14637798	-0.7402388
Infliximab	Blood sodium decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	42	3094	22460	2980559	0.8	0.618	1.022	0.804	1.984	0.803	0.159	0.80075496	-0.2231436
Infliximab	Blood sodium increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	2	548	22500	2983105	0.25	0.081	0.628	0.22	5.478	0.22	0.019	-0.781417	-1.3862944
Infliximab	Blood test abnormal	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	4	381	22498	2983272	0.622	0.272	1.264	0.647	0.754	0.647	0.385	0.35416251	-0.4748152
Infliximab	Blood testosterone decreased	Reproductive hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	275	22501	2983378	0.32	0.074	1	0.27	1.936	0.27	0.164	-0.6273039	-1.1394343
Infliximab	Blood thyroid stimulating hormone	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	21	22501	2983632	0.931	0.215	2.907	1.986	0.45	1.987	0.502	0.76921993	-0.071496
Infliximab	Blood thyroid stimulating hormone decreased	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	4	460	22498	2983193	0.567	0.248	1.153	0.582	1.196	0.582	0.274	0.14956466	-0.567396
Infliximab	Blood thyroid stimulating hormone increased	Pituitary analyses anterior	Endocrine investigations (incl sex hormones)	Inv	1968-2006	2	789	22500	2982864	0.207	0.067	0.52	0.18	7.513	0.18	0.006	-1.2172131	-1.5750365
Infliximab	Blood triglycerides	Triglyceride analyses	Lipid analyses	Inv	1968-2006	2	55	22500	2983598	1.11	0.36	2.783	1.777	0.639	1.777	0.424	1.06145149	0.10436002
Infliximab	Blood triglycerides increased	Triglyceride analyses	Lipid analyses	Inv	1968-2006	13	3670	22489	2979983	0.25	0.156	0.382	0.242	30.921	0.242	2.688e-8	-1.0416072	-1.3862944
Infliximab	Blood urea	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	10	211	22492	2983442	1.541	0.905	2.49	1.79	3.34	1.793	0.068	2.04018278	0.43243156
Infliximab	Blood urea abnormal	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	4	165	22498	2983488	0.944	0.412	1.918	1.096	0.033	1.096	0.856	1.13148638	-0.0576291
Infliximab	Blood urea decreased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	3	411	22499	2983242	0.465	0.181	1.029	0.46	1.862	0.46	0.172	-0.0462809	-0.7657179
Infliximab	Blood urea increased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	32	15296	22470	2968357	0.371	0.276	0.491	0.365	35.218	0.364	2.948e-9	-1.8285385	-0.9915532
Infliximab	Blood urea nitrogen/creatinine ratio	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	1	22501	2983652	1.323	0.304	4.176	34.131	17.751	34.131	0.00002518	0.967721	0.27990189
Infliximab	Blood uric acid abnormal	Metabolism tests NEC	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	26	22501	2983627	0.931	0.215	2.907	1.943	0.447	1.943	0.504	0.72358631	-0.071496
Infliximab	Blood uric acid decreased	Metabolism tests NEC	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	2	84	22500	2983569	1.08	0.35	2.708	1.678	0.519	1.678	0.471	0.85710281	0.07696104
Infliximab	Blood uric acid increased	Metabolism tests NEC	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	3	707	22499	2982946	0.333	0.129	0.735	0.312	4.472	0.312	0.034	-0.669865	-1.0996128
Infliximab	Blood urine	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	7	348	22495	2983305	0.862	0.457	1.51	0.92	0.047	0.92	0.828	1.11821911	-0.1485
Infliximab	Blood urine present	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	25	4211	22477	2979442	0.761	0.543	1.041	0.769	1.729	0.768	0.189	-0.343998	-0.2731219
Infliximab	Bloody discharge	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	3	125	22499	2983528	0.943	0.367	2.085	1.157	0.061	1.157	0.805	1.01963077	-0.058689
Infliximab	Blunted affect	Affect alterations NEC	Mood disorders and disturbances NEC	Psych	1968-2006	1	57	22501	2983596	0.74	0.171	2.309	1.063	0.004	1.063	0.952	0.46893872	-0.3011051
Infliximab	Body temperature	Physical examination procedures	Physical examination topics	Inv	1968-2006	1	28	22501	2983625	0.915	0.212	2.858	1.836	0.377	1.836	0.539	0.70572945	-0.0888312
Infliximab	Body temperature decreased	Physical examination procedures	Physical examination topics	Inv	1968-2006	14	1096	22488	2982557	0.765	0.488	1.155	0.781	0.846	0.781	0.358	0.67694276	-0.2678794
Infliximab	Body temperature increased	Physical examination procedures	Physical examination topics	Inv	1968-2006	99	3298	22403	2980355	1.62	1.37	1.905	1.668	25.546	1.671	4.319e-7	1.90744728	0.48242615
Infliximab	Bone cancer metastatic	Bone neoplasms malignant (excl sarcomas)	Skeletal neoplasms malignant and unspecified	Neopl	1968-2006	2	18	22500	2983635	1.788	0.578	4.512	7.413	9.754	7.414	0.002	1.37284789	0.58109768
Infliximab	Bone cyst	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	3	48	22499	2983605	1.828	0.71	4.048	3.967	6.039	3.967	0.014	1.52263875	0.60322247
Infliximab	Bone cyst excision	Bone therapeutic procedures NEC	Bone and joint therapeutic procedures	Surg	1968-2006	1	0	22501	2983653	1.345	0.308	4.256	1075.772	51.692	1083.348	6.493e-13	0.97840063	0.29639401
Infliximab	Bone density decreased	Musculoskeletal and soft tissue imaging procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	4	898	22498	2982755	0.289	0.126	0.588	0.273	7.747	0.273	0.005	-0.6438667	-1.2413286
Infliximab	Bone disorder	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	16	2964	22486	2980689	0.572	0.375	0.842	0.571	5.079	0.571	0.024	-0.4674529	-0.5586163
Infliximab	Bone erosion	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	1	61	22501	2983592	0.675	0.156	2.106	0.875	0.017	0.875	0.895	0.43912725	-0.3930426
Infliximab	Bone graft	Bone therapeutic procedures NEC	Bone and joint therapeutic procedures	Surg	1968-2006	3	91	22499	2983562	1.314	0.511	2.906	1.984	1.364	1.985	0.243	1.22051305	0.27307592
Infliximab	Bone lesion	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	2	179	22500	2983474	0.681	0.221	1.708	0.773	0.129	0.773	0.719	0.33840689	-0.384193
Infliximab	Bone marrow disorder	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	8	264	22494	2983389	1.298	0.716	2.203	1.492	1.235	1.493	0.266	1.5567835	0.26082462
Infliximab	Bone marrow failure	Marrow depression and hypoplastic anaemias	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	47	6510	22455	2977143	0.778	0.61	0.982	0.781	2.857	0.78	0.091	-0.0752239	-0.2510288
Infliximab	Bone marrow toxicity	Marrow depression and hypoplastic anaemias	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	4	142	22498	2983511	1.192	0.52	2.421	1.513	0.679	1.513	0.41	1.24554694	0.17563257
Infliximab	Bone marrow transplant	Haematological therapeutic procedures NEC	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	2	266	22500	2983387	0.447	0.145	1.121	0.438	1.418	0.438	0.234	-0.0138805	-0.8051967
Infliximab	Bone marrow transplant rejection	Transplant rejections	Immune disorders NEC	Immun	1968-2006	1	30	22501	2983623	0.914	0.211	2.852	1.821	0.368	1.821	0.544	0.68809089	-0.0899247
Infliximab	Bone marrow tumour cell infiltration	Haematologic neoplasms NEC	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	1	16	22501	2983637	1.011	0.234	3.159	2.698	0.958	2.698	0.328	0.81634411	0.01093994
Infliximab	Bone neoplasm	Bone neoplasms unspecified malignancy	Skeletal neoplasms malignant and unspecified	Neopl	1968-2006	1	195	22501	2983458	0.671	0.155	2.093	0.863	0.021	0.863	0.886	-0.3137617	-0.3989861
Infliximab	Bone neoplasm malignant	Bone neoplasms malignant (excl sarcomas)	Skeletal neoplasms malignant and unspecified	Neopl	1968-2006	7	138	22495	2983515	2.007	1.064	3.519	2.788	7.461	2.789	0.006	1.92878928	0.69664107
Infliximab	Bone pain	Bone related signs and symptoms	Bone disorders (excl congenital and fractures)	Musc	1968-2006	41	6596	22461	2977057	0.644	0.495	0.825	0.641	8.129	0.64	0.004	-0.2850587	-0.4400566
Infliximab	Bone sarcoma	Bone sarcomas	Skeletal neoplasms malignant and unspecified	Neopl	1968-2006	2	95	22500	2983558	1.083	0.351	2.716	1.677	0.531	1.677	0.466	0.78658155	0.07973497
Infliximab	Bone scan abnormal	Musculoskeletal and soft tissue imaging procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	4	136	22498	2983517	1.579	0.689	3.21	2.404	2.981	2.404	0.084	1.2768465	0.45679174
Infliximab	Bone tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	14	27	22488	2983626	16.044	7.907	26.106	31.7	240.363	31.721	0	3.50988655	2.77533495
Infliximab	Borrelia burgdorferi serology positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	8	22501	2983645	1.15	0.266	3.599	5.051	2.966	5.051	0.085	0.89509832	0.13976194
Infliximab	Borrelia infection	Borrelial infections	Bacterial infectious disorders	Infec	1968-2006	1	24	22501	2983629	0.976	0.226	3.048	2.261	0.698	2.261	0.403	0.74166694	-0.0242927
Infliximab	Bovine tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	2	112	22500	2983541	1.047	0.339	2.624	1.565	0.399	1.566	0.527	0.6839525	0.04592893
Infliximab	Bowel sounds abnormal	Abdominal findings abnormal	Gastrointestinal signs and symptoms	Gastr	1968-2006	10	534	22492	2983119	1.166	0.685	1.883	1.275	0.576	1.275	0.448	1.10577678	0.15357909
Infliximab	Bowens disease	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	9	50	22493	2983603	4.575	2.558	7.99	10.582	63.135	10.586	1.93e-15	2.78335721	1.5206067
Infliximab	Bowenoid papulosis	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	1	4	22501	2983649	1.287	0.296	4.048	16.2	10.76	16.2	0.001	0.93614837	0.25231393
Infliximab	Bradyarrhythmia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	6	197	22496	2983456	1.375	0.694	2.504	1.686	1.607	1.686	0.205	1.46327193	0.31845373
Infliximab	Bradycardia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	64	19346	22438	2964307	0.475	0.385	0.58	0.469	38.216	0.468	6.332e-10	-1.1905414	-0.7444405
Infliximab	Bradycardia foetal	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	1	229	22501	2983424	0.33	0.076	1.032	0.282	1.807	0.282	0.179	-0.4554161	-1.1086626
Infliximab	Bradyphrenia	Thinking disturbances	Disturbances in thinking and perception	Psych	1968-2006	4	356	22498	2983297	0.65	0.284	1.32	0.684	0.58	0.684	0.446	0.42545506	-0.4307829
Infliximab	Brain abscess	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	15	198	22487	2983455	3.386	2.191	5.052	4.642	39.121	4.646	3.983e-10	2.61367782	1.21964928
Infliximab	Brain cancer metastatic	Central nervous system neoplasms malignant NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	20	22501	2983633	0.967	0.224	3.02	2.268	0.644	2.268	0.422	0.77852244	-0.0335568
Infliximab	Brain damage	Structural brain disorders NEC	Structural brain disorders	Nerv	1968-2006	5	740	22497	2982913	0.445	0.211	0.85	0.44	3.547	0.44	0.06	-0.1435664	-0.809681
Infliximab	Brain death	Death and sudden death	Fatal outcomes	Genrl	1968-2006	6	499	22496	2983154	0.603	0.304	1.098	0.615	1.427	0.614	0.232	0.5392393	-0.5058381
Infliximab	Brain herniation	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	7	507	22495	2983146	0.836	0.443	1.465	0.889	0.096	0.889	0.757	0.71168984	-0.1791267
Infliximab	Brain hypoxia	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	1	343	22501	2983310	0.368	0.085	1.148	0.33	1.367	0.33	0.242	-0.8489263	-0.9996723
Infliximab	Brain mass	Structural brain disorders NEC	Structural brain disorders	Nerv	1968-2006	10	82	22492	2983571	3.691	2.161	5.999	6.042	39.863	6.045	2.724e-10	2.69268078	1.30589742
Infliximab	Brain natriuretic peptide increased	Metabolism tests NEC	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	197	22501	2983456	0.381	0.088	1.189	0.347	1.242	0.347	0.265	-0.3224906	-0.9649559
Infliximab	Brain neoplasm	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	17	651	22485	2983002	1.444	0.96	2.104	1.567	3.351	1.567	0.067	1.57376295	0.36741704
Infliximab	Brain neoplasm benign	Nervous system neoplasms benign NEC	Nervous system neoplasms benign	Neopl	1968-2006	4	34	22498	2983619	2.615	1.137	5.36	7.134	18.663	7.135	0.0000156	1.94992901	0.9612641
Infliximab	Brain neoplasm malignant	Central nervous system neoplasms malignant NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	7	156	22495	2983497	1.812	0.961	3.175	2.385	5.332	2.385	0.021	1.83845582	0.59443121
Infliximab	Brain oedema	Increased intracranial pressure disorders	Increased intracranial pressure and hydrocephalus	Nerv	1968-2006	24	3322	22478	2980331	0.62	0.44	0.855	0.62	5.521	0.619	0.019	-0.071571	-0.4780358
Infliximab	Brain operation	Skull and brain therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	1	42	22501	2983611	0.833	0.193	2.6	1.416	0.118	1.417	0.731	0.58656124	-0.1827216
Infliximab	Brain scan abnormal	Central nervous system imaging procedures	Neurological and special sense investigations	Inv	1968-2006	5	586	22497	2983067	0.574	0.272	1.097	0.583	1.452	0.582	0.228	0.13453142	-0.5551259
Infliximab	Brain stem haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	93	22499	2983560	1.292	0.502	2.856	1.895	1.24	1.895	0.265	1.20788974	0.25619141
Infliximab	Brain stem infarction	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	344	22499	2983309	0.586	0.228	1.296	0.611	0.733	0.611	0.392	0.14203902	-0.5344355
Infliximab	Brain stem ischaemia	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	63	22499	2983590	1.704	0.662	3.771	3.318	4.522	3.319	0.033	1.40991958	0.53297843
Infliximab	Breast abscess	Breast infections	Infections - pathogen class unspecified	Infec	1968-2006	3	81	22499	2983572	1.437	0.558	3.178	2.328	2.15	2.328	0.143	1.28534125	0.36255761
Infliximab	Breast adenoma	Breast and nipple neoplasms benign	Breast neoplasms benign (incl nipple)	Neopl	1968-2006	1	3	22501	2983650	1.296	0.298	4.08	20.626	12.086	20.626	0.001	0.946596	0.2592826
Infliximab	Breast cancer	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	219	7527	22283	2976126	1.127	1.007	1.257	1.135	3.507	1.138	0.061	1.88469215	0.11955924
Infliximab	Breast cancer female	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	49	6287	22453	2977366	0.339	0.267	0.426	0.332	67.195	0.329	2.459e-16	0.03223696	-1.0817552
Infliximab	Breast cancer in situ	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	15	595	22487	2983058	1.323	0.857	1.972	1.429	1.875	1.43	0.171	1.51222151	0.27990189
Infliximab	Breast cancer metastatic	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	13	552	22489	2983101	1.063	0.666	1.627	1.126	0.178	1.126	0.673	1.40965806	0.0610951
Infliximab	Breast cancer recurrent	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	8	217	22494	2983436	1.64	0.905	2.784	2.015	3.886	2.016	0.049	1.73449047	0.49469624
Infliximab	Breast cancer stage I	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	4	70	22498	2983583	1.815	0.792	3.69	3.059	5.149	3.06	0.023	1.67514796	0.59608547
Infliximab	Breast cancer stage II	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	5	95	22497	2983558	1.771	0.84	3.384	2.647	4.624	2.647	0.032	1.76793259	0.57154436
Infliximab	Breast cancer stage III	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	5	83	22497	2983570	1.897	0.899	3.624	2.94	5.875	2.942	0.015	1.84402232	0.64027369
Infliximab	Breast cancer stage IV	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	1	203	22501	2983450	0.367	0.085	1.145	0.323	1.39	0.323	0.238	-0.3483647	-1.0023934
Infliximab	Breast cellulitis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	23	22501	2983630	0.984	0.228	3.073	2.392	0.752	2.392	0.386	0.75079293	-0.0161294
Infliximab	Breast cyst	Benign and malignant breast neoplasms	Breast disorders	Repro	1968-2006	8	130	22494	2983523	2.19	1.209	3.72	3.044	10.118	3.045	0.001	2.13543029	0.78390154
Infliximab	Breast discharge	Breast signs and symptoms	Breast disorders	Repro	1968-2006	2	317	22500	2983336	0.392	0.127	0.983	0.371	2.095	0.371	0.148	-0.1863844	-0.9364934
Infliximab	Breast discomfort	Breast signs and symptoms	Breast disorders	Repro	1968-2006	1	66	22501	2983587	0.625	0.144	1.949	0.752	0.079	0.752	0.778	0.40270872	-0.4700036
Infliximab	Breast disorder	Breast disorders NEC	Breast disorders	Repro	1968-2006	3	221	22499	2983432	0.782	0.304	1.729	0.887	0.041	0.887	0.839	0.56859324	-0.2459005
Infliximab	Breast disorder female	Breast disorders NEC	Breast disorders	Repro	1968-2006	1	46	22501	2983607	0.878	0.203	2.742	1.653	0.239	1.653	0.625	0.5542459	-0.1301087
Infliximab	Breast disorder male	Breast disorders NEC	Breast disorders	Repro	1968-2006	1	4	22501	2983649	1.295	0.298	4.078	18.65	11.936	18.659	0.001	0.93614837	0.2585107
Infliximab	Breast engorgement	Breast signs and symptoms	Breast disorders	Repro	1968-2006	2	526	22500	2983127	0.447	0.145	1.122	0.438	1.419	0.438	0.234	-0.7342128	-0.8051967
Infliximab	Breast fibroma	Breast and nipple neoplasms benign	Breast neoplasms benign (incl nipple)	Neopl	1968-2006	1	6	22501	2983647	1.249	0.288	3.919	11.334	7.069	11.334	0.008	0.91547736	0.22234323
Infliximab	Breast fibrosis	Breast disorders NEC	Breast disorders	Repro	1968-2006	1	17	22501	2983636	1.065	0.246	3.33	3.261	1.498	3.261	0.221	0.80679534	0.0629748
Infliximab	Breast haemorrhage	Breast signs and symptoms	Breast disorders	Repro	1968-2006	1	40	22501	2983613	0.87	0.201	2.715	1.592	0.212	1.592	0.645	0.60299444	-0.1392621
Infliximab	Breast infection	Breast infections	Infections - pathogen class unspecified	Infec	1968-2006	1	42	22501	2983611	0.811	0.187	2.53	1.325	0.075	1.325	0.784	0.58656124	-0.2094872
Infliximab	Breast mass	Breast disorders NEC	Breast disorders	Repro	1968-2006	16	662	22486	2982991	1.555	1.021	2.291	1.716	4.559	1.716	0.033	1.4734091	0.44147555
Infliximab	Breast microcalcification	Breast disorders NEC	Breast disorders	Repro	1968-2006	5	120	22497	2983533	1.726	0.818	3.298	2.541	4.198	2.542	0.04	1.62123576	0.54580659
Infliximab	Breast necrosis	Breast disorders NEC	Breast disorders	Repro	1968-2006	1	46	22501	2983607	0.729	0.169	2.275	1.03	0.001	1.03	0.977	0.5542459	-0.3160815
Infliximab	Breast neoplasm	Breast neoplasms unspecified malignancy	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	2	2168	22500	2981485	0.569	0.184	1.425	0.601	0.523	0.601	0.47	-2.5348736	-0.5638748
Infliximab	Breast operation	Breast therapeutic procedures NEC	Breast therapeutic procedures	Surg	1968-2006	1	115	22501	2983538	0.379	0.088	1.184	0.34	1.269	0.34	0.26	0.08738197	-0.9702191
Infliximab	Breast pain	Breast signs and symptoms	Breast disorders	Repro	1968-2006	5	7045	22497	2976608	0.15	0.071	0.286	0.137	27.138	0.137	1.894e-7	-3.1780542	-1.89712
Infliximab	Breast tenderness	Breast signs and symptoms	Breast disorders	Repro	1968-2006	1	1358	22501	2982295	0.06	0.014	0.19	0.042	22.42	0.042	2.191e-6	-2.4933799	-2.8134107
Infliximab	Breath odour	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	2	697	22500	2982956	0.444	0.144	1.113	0.433	1.447	0.433	0.229	-1.065962	-0.8119307
Infliximab	Breath sounds abnormal	Physical examination procedures	Physical examination topics	Inv	1968-2006	9	635	22493	2983018	0.994	0.567	1.642	1.067	0.037	1.067	0.848	0.76962895	-0.0060181
Infliximab	Breech presentation	Foetal position and presentation abnormalities	Foetal complications	Preg	1968-2006	1	195	22501	2983458	0.323	0.075	1.008	0.275	1.909	0.275	0.167	-0.3137617	-1.130103
Infliximab	Bronchial carcinoma	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	9	92	22493	2983561	3.072	1.751	5.089	4.849	25.282	4.851	4.953e-7	2.49873568	1.12232882
Infliximab	Bronchial hyperactivity				1968-2006	1	54	22501	2983599	0.908	0.21	2.834	1.827	0.341	1.827	0.559	0.49170863	-0.0965109
Infliximab	Bronchial obstruction	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	4	272	22498	2983381	0.889	0.388	1.805	1.011	0	1.011	0.983	0.69462514	-0.117658
Infliximab	Bronchial oedema	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	1	13	22501	2983640	1.128	0.261	3.527	4.575	2.454	4.575	0.117	0.84537553	0.12044615
Infliximab	Bronchiectasis	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	40	327	22462	2983326	5.832	4.457	7.552	8.056	202.724	8.071	0	3.4407723	1.76335999
Infliximab	Bronchiolitis	Respiratory syncytial viral infections	Viral infectious disorders	Infec	1968-2006	8	1222	22494	2982431	0.65	0.359	1.104	0.663	1.338	0.663	0.247	-0.1929819	-0.4307829
Infliximab	Bronchioloalveolar carcinoma	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	22	22500	2983631	1.636	0.529	4.113	5.343	5.889	5.343	0.015	1.33575551	0.49225424
Infliximab	Bronchitis	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	155	6474	22347	2977179	2.137	1.869	2.433	2.232	99.59	2.241	1.875e-23	1.60978984	0.75940298
Infliximab	Bronchitis acute	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	23	709	22479	2982944	2.023	1.425	2.805	2.262	15.203	2.263	0.00009657	1.87795342	0.70458156
Infliximab	Bronchitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	23	22500	2983630	1.611	0.522	4.051	4.907	5.423	4.908	0.02	1.32662952	0.4768551
Infliximab	Bronchitis chronic	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	7	244	22495	2983409	1.498	0.794	2.625	1.842	2.53	1.842	0.112	1.4635681	0.40413089
Infliximab	Bronchomalacia	Bronchial conditions NEC	Bronchial disorders (excl neoplasms)	Resp	1968-2006	1	5	22501	2983648	1.212	0.28	3.798	8.676	5.012	8.679	0.025	0.92577585	0.19227189
Infliximab	Bronchopleural fistula	Pleural conditions NEC	Pleural disorders	Resp	1968-2006	1	33	22501	2983620	0.854	0.198	2.667	1.518	0.169	1.518	0.681	0.66203088	-0.1578241
Infliximab	Bronchopneumonia	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	55	1528	22447	2982125	2.223	1.774	2.758	2.386	41.711	2.389	1.058e-10	2.11216386	0.79885763
Infliximab	Bronchopulmonary aspergillosis	Aspergillus infections	Fungal infectious disorders	Infec	1968-2006	33	509	22469	2983144	3.998	2.983	5.269	4.896	92.839	4.905	5.671e-22	2.73808249	1.38579424
Infliximab	Bronchopulmonary aspergillosis allergic	Aspergillus infections	Fungal infectious disorders	Infec	1968-2006	1	13	22501	2983640	1.139	0.263	3.562	4.863	2.673	4.864	0.102	0.84537553	0.13015068
Infliximab	Bronchoscopy abnormal	Respiratory tract and thoracic imaging procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	3	90	22499	2983563	1.502	0.584	3.323	2.522	2.623	2.522	0.105	1.22686636	0.40679755
Infliximab	Bronchospasm	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	118	4782	22384	2978871	2.252	1.931	2.613	2.34	87.882	2.353	6.949e-21	1.64601283	0.81181871
Infliximab	Brown-Sequard syndrome	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	12	22501	2983641	1.204	0.278	3.773	6.59	4.633	6.59	0.031	0.85518395	0.18564935
Infliximab	Brucellosis	Brucella infections	Bacterial infectious disorders	Infec	1968-2006	1	6	22501	2983647	1.296	0.298	4.081	15.705	12.025	15.708	0.001	0.91547736	0.2592826
Infliximab	Bruxism	Stereotypies and automatisms	Changes in physical activity	Psych	1968-2006	2	473	22500	2983180	0.27	0.087	0.677	0.24	4.768	0.24	0.029	-0.6137214	-1.3093333
Infliximab	Budd-Chiari syndrome	Hepatic vascular disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	3	345	22499	2983308	1.038	0.403	2.294	1.332	0.241	1.332	0.624	0.13903976	0.03729578
Infliximab	Bulbar palsy	Mixed cranial nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	34	22501	2983619	0.985	0.228	3.078	2.376	0.76	2.376	0.383	0.65344776	-0.0151136
Infliximab	Bulimia nervosa	Eating disorders NEC	Eating disorders and disturbances	Psych	1968-2006	1	94	22501	2983559	0.529	0.122	1.65	0.562	0.336	0.562	0.562	0.21418718	-0.6367668
Infliximab	Bullous lung disease	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	3	29	22499	2983624	2.299	0.889	5.132	7.867	15.775	7.867	0.00007133	1.67935201	0.83247425
Infliximab	Bundle branch block	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	5	1215	22497	2982438	0.897	0.426	1.714	0.996	0	0.996	0.993	-0.7673218	-0.1086994
Infliximab	Bundle branch block bilateral	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	1	35	22501	2983618	0.993	0.23	3.102	2.515	0.816	2.515	0.366	0.64491541	-0.0070246
Infliximab	Bundle branch block left	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	18	1058	22484	2982595	1.134	0.763	1.636	1.19	0.53	1.19	0.467	1.05799046	0.12575121
Infliximab	Bundle branch block right	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	12	1232	22490	2982421	0.669	0.412	1.041	0.678	1.803	0.678	0.179	0.32279119	-0.4019712
Infliximab	Bunion operation	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	3	30	22499	2983623	2.132	0.826	4.737	6.564	11.432	6.566	0.001	1.67066555	0.75706051
Infliximab	Burkitts lymphoma	Burkitts lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	2	48	22500	2983605	1.435	0.465	3.602	3.165	2.926	3.165	0.087	1.11543829	0.36116485
Infliximab	Burning sensation	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	86	6232	22416	2977421	0.957	0.799	1.138	0.962	0.126	0.962	0.723	0.83537008	-0.0439519
Infliximab	Burns first degree	Thermal burns	Injuries by physical agents	Inj&P	1968-2006	1	56	22501	2983597	0.761	0.176	2.376	1.134	0.015	1.134	0.901	0.47648884	-0.2731219
Infliximab	Burns third degree	Thermal burns	Injuries by physical agents	Inj&P	1968-2006	1	124	22501	2983529	0.486	0.112	1.518	0.49	0.519	0.49	0.471	0.03627232	-0.7215467
Infliximab	Bursa disorder	Bursal disorders	Synovial and bursal disorders	Musc	1968-2006	3	18	22499	2983635	2.203	0.853	4.902	7.224	13.176	7.226	0.0002836	1.77852258	0.78982007
Infliximab	Bursa removal	Fascial and bursal therapeutic procedures	Soft tissue therapeutic procedures	Surg	1968-2006	1	5	22501	2983648	1.31	0.301	4.128	18.302	14.53	18.302	0.0001379	0.92577585	0.27002714
Infliximab	Bursal operation	Fascial and bursal therapeutic procedures	Soft tissue therapeutic procedures	Surg	1968-2006	1	0	22501	2983653	1.378	0.314	4.385	1089.712	93.672	1097.429	3.723e-22	0.97840063	0.32063317
Infliximab	Bursitis	Bursal disorders	Synovial and bursal disorders	Musc	1968-2006	45	929	22457	2982724	3.644	2.838	4.621	4.254	101.614	4.261	6.745e-24	2.46077926	1.29308198
Infliximab	Bursitis infective	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	11	44	22491	2983609	6.495	3.528	13.709	15.208	110.497	15.218	7.628e-26	3.07667257	1.87103265
Infliximab	Bursitis infective staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	3	22501	2983650	1.291	0.297	4.061	18.13	11.249	18.13	0.001	0.946596	0.25541711
Infliximab	Buttock pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	6	294	22496	2983359	0.929	0.469	1.691	1.02	0.002	1.02	0.962	1.09789109	-0.0736465
Infliximab	C-reactive protein	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	7	71	22495	2983582	2.661	1.41	4.67	4.447	16.75	4.453	0.00004264	2.32568468	0.97870199
Infliximab	C-reactive protein decreased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	2	29	22500	2983624	1.364	0.442	3.422	2.826	2.25	2.826	0.134	1.27305348	0.31042156
Infliximab	C-reactive protein increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	151	5084	22351	2978569	1.986	1.734	2.265	2.059	78.582	2.067	7.674e-19	1.90602059	0.68612257
Infliximab	CD4 lymphocytes decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	6	632	22496	2983021	0.548	0.277	0.998	0.555	2.143	0.555	0.143	0.26623262	-0.60148
Infliximab	CD4 lymphocytes increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	30	22501	2983623	0.873	0.202	2.724	1.595	0.221	1.595	0.638	0.68809089	-0.1358197
Infliximab	CD4/CD8 ratio decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	20	22501	2983633	1.098	0.254	3.431	3.706	1.938	3.706	0.164	0.77852244	0.09349034
Infliximab	CD8 lymphocytes decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	26	22499	2983627	2.085	0.808	4.628	5.49	10.353	5.491	0.001	1.70572963	0.73476886
Infliximab	CD8 lymphocytes increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	14	22501	2983639	1.135	0.262	3.551	4.481	2.608	4.481	0.106	0.83563334	0.12663265
Infliximab	CREST syndrome	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	2	24	22500	2983629	1.638	0.53	4.12	5.161	5.938	5.161	0.015	1.31756088	0.49347599
Infliximab	CSF bacteria identified	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	28	22501	2983625	1.002	0.232	3.131	2.476	0.883	2.476	0.347	0.70572945	0.001998
Infliximab	CSF cell count increased	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	1	24	22501	2983629	0.992	0.229	3.098	2.461	0.805	2.461	0.37	0.74166694	-0.0080322
Infliximab	CSF culture positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	4	42	22498	2983611	2.503	1.089	5.116	6.242	15.959	6.244	0.00006472	1.88418561	0.91749001
Infliximab	CSF glucose abnormal	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	1	45	22501	2983608	0.937	0.217	2.927	2.029	0.478	2.029	0.489	0.56225713	-0.065072
Infliximab	CSF glucose decreased	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	2	38	22500	2983615	1.518	0.492	3.811	4.027	3.938	4.027	0.047	1.19624438	0.41739368
Infliximab	CSF lymphocyte count increased	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	1	41	22501	2983612	0.862	0.199	2.69	1.563	0.189	1.563	0.664	0.59475445	-0.1485
Infliximab	CSF oligoclonal band present	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	2	13	22500	2983640	1.791	0.579	4.52	7.889	9.894	7.889	0.002	1.4205959	0.58277412
Infliximab	CSF pressure increased	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	1	110	22501	2983543	0.569	0.131	1.775	0.633	0.204	0.633	0.651	0.11657848	-0.5638748
Infliximab	CSF protein	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	1	12	22501	2983641	1.053	0.243	3.289	3.129	1.353	3.129	0.245	0.85518395	0.05164323
Infliximab	CSF protein abnormal	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	1	28	22501	2983625	0.976	0.226	3.048	2.342	0.698	2.342	0.404	0.70572945	-0.0242927
Infliximab	CSF protein increased	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	11	412	22491	2983241	1.603	0.965	2.538	1.85	4.116	1.85	0.042	1.51516153	0.47187687
Infliximab	CSF test abnormal	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	6	607	22496	2983046	1.359	0.686	2.475	1.656	1.506	1.657	0.22	0.31376263	0.30674914
Infliximab	CSF white blood cell count increased	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	2	30	22500	2983623	1.546	0.501	3.884	4.055	4.337	4.056	0.037	1.26431441	0.43567095
Infliximab	CSF white blood cell count positive	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	2	113	22500	2983540	0.947	0.307	2.375	1.307	0.141	1.307	0.707	0.67813693	-0.0544562
Infliximab	Cachexia	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	11	1200	22491	2982453	0.884	0.532	1.399	0.923	0.07	0.923	0.792	0.24230961	-0.1232982
Infliximab	Caecitis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	2	208	22500	2983445	0.518	0.168	1.299	0.533	0.821	0.533	0.365	0.21117968	-0.65778
Infliximab	Caesarean section	Obstetric therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	33	3852	22469	2979801	0.436	0.326	0.575	0.43	24.817	0.429	6.303e-7	0.16400717	-0.830113
Infliximab	Calcinosis	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	18	671	22484	2982982	1.761	1.185	2.541	1.96	8.071	1.96	0.004	1.61444696	0.56588183
Infliximab	Calciphylaxis	Calcium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	1	48	22501	2983605	0.752	0.174	2.346	1.1	0.009	1.1	0.923	0.53835564	-0.285019
Infliximab	Calcium deficiency	Calcium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	1	39	22501	2983614	0.83	0.192	2.59	1.409	0.111	1.409	0.739	0.61128176	-0.1863296
Infliximab	Calcium ionised decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	37	22501	2983616	0.799	0.185	2.495	1.276	0.057	1.276	0.81	0.62800058	-0.2243943
Infliximab	Calcium metabolism disorder	Calcium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	1	243	22501	2983410	0.99	0.229	3.091	2.476	0.789	2.476	0.374	-0.5099301	-0.0100503
Infliximab	Calculus bladder	Urinary tract lithiasis (excl renal)	Urolithiases	Renal	1968-2006	3	179	22499	2983474	1.171	0.455	2.588	1.616	0.674	1.616	0.412	0.74886559	0.15785808
Infliximab	Calculus ureteric	Urinary tract lithiasis (excl renal)	Urolithiases	Renal	1968-2006	9	203	22493	2983450	2.335	1.333	3.861	3.258	12.569	3.259	0.0003921	1.9397731	0.84801189
Infliximab	Calculus urethral	Urinary tract lithiasis (excl renal)	Urolithiases	Renal	1968-2006	1	16	22501	2983637	1.164	0.269	3.643	5.401	3.277	5.401	0.07	0.81634411	0.15186235
Infliximab	Calculus urinary	Urinary tract lithiasis (excl renal)	Urolithiases	Renal	1968-2006	5	451	22497	2983202	1.33	0.631	2.54	1.688	1.309	1.689	0.252	0.43204708	0.28517894
Infliximab	Camptodactyly acquired	Extremity deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	3	1	22499	2983652	3.368	1.151	16.669	77.877	75.226	77.877	4.198e-18	1.94659604	1.2143191
Infliximab	Campylobacter gastroenteritis	Campylobacter infections	Bacterial infectious disorders	Infec	1968-2006	1	13	22501	2983640	1.076	0.249	3.362	3.366	1.625	3.366	0.202	0.84537553	0.07325046
Infliximab	Campylobacter infection	Campylobacter infections	Bacterial infectious disorders	Infec	1968-2006	1	37	22501	2983616	0.793	0.183	2.476	1.249	0.049	1.249	0.825	0.62800058	-0.2319321
Infliximab	Campylobacter intestinal infection	Campylobacter infections	Bacterial infectious disorders	Infec	1968-2006	1	24	22501	2983629	0.926	0.214	2.89	1.896	0.423	1.896	0.516	0.74166694	-0.076881
Infliximab	Candida pneumonia	Candida infections	Fungal infectious disorders	Infec	1968-2006	8	33	22494	2983620	4.431	2.389	8.025	11.713	59.483	11.717	1.233e-14	2.77292026	1.48862529
Infliximab	Candida sepsis	Candida infections	Fungal infectious disorders	Infec	1968-2006	13	134	22489	2983519	3.52	2.204	5.401	5.193	39.498	5.195	3.285e-10	2.72582485	1.25846099
Infliximab	Candida serology positive	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	3	36	22499	2983617	2.032	0.788	4.509	5.333	9.297	5.333	0.002	1.61961718	0.70902053
Infliximab	Candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	114	3167	22388	2980486	2.88	2.464	3.351	3.103	150.751	3.114	1.188e-34	2.15734108	1.05779029
Infliximab	Candiduria	Candida infections	Fungal infectious disorders	Infec	1968-2006	3	44	22499	2983609	1.527	0.593	3.377	2.553	2.845	2.553	0.092	1.55424615	0.42330503
Infliximab	Capillary disorder	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	5	149	22497	2983504	1.705	0.808	3.257	2.428	4.002	2.428	0.045	1.46787776	0.53356511
Infliximab	Capillary fragility	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	14	22501	2983639	1.163	0.269	3.641	5.651	3.269	5.652	0.071	0.83563334	0.15100287
Infliximab	Capillary leak syndrome	Vascular hypotensive disorders	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	2	289	22500	2983364	0.427	0.138	1.07	0.414	1.643	0.414	0.2	-0.0942376	-0.8509713
Infliximab	Capnocytophagia infection	Capnocytophagia infections	Bacterial infectious disorders	Infec	1968-2006	1	4	22501	2983649	1.292	0.298	4.067	14.708	11.524	14.708	0.001	0.93614837	0.25619141
Infliximab	Carbohydrate antigen 125 increased	Cell marker procedures	Immunology and allergy investigations	Inv	1968-2006	2	69	22500	2983584	0.899	0.291	2.253	1.197	0.062	1.197	0.804	0.95918425	-0.1064722
Infliximab	Carbohydrate antigen 19-9 increased	Cell marker procedures	Immunology and allergy investigations	Inv	1968-2006	2	47	22500	2983606	1.299	0.421	3.259	2.445	1.72	2.446	0.19	1.12331827	0.26159474
Infliximab	Carbon dioxide abnormal	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	2	60	22500	2983593	1.17	0.379	2.934	1.987	0.921	1.987	0.337	1.0240899	0.15700375
Infliximab	Carbon dioxide decreased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	6	725	22496	2982928	0.722	0.364	1.314	0.755	0.465	0.755	0.496	0.10200704	-0.3257301
Infliximab	Carbon monoxide poisoning	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	1	107	22501	2983546	0.56	0.13	1.748	0.617	0.228	0.617	0.633	0.13438423	-0.5798185
Infliximab	Carboxyhaemoglobin increased	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	1	19	22501	2983634	1.078	0.249	3.371	3.66	1.66	3.66	0.198	0.78788532	0.07510747
Infliximab	Carcinoid syndrome	Ectopic hormone secretion syndromes associated with neoplasias	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	33	22501	2983620	1.022	0.236	3.194	2.83	1.046	2.83	0.306	0.66203088	0.02176149
Infliximab	Carcinoid tumour	Carcinoid tumours	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	55	22501	2983598	0.751	0.174	2.345	1.101	0.009	1.101	0.924	0.48407867	-0.2863496
Infliximab	Carcinoid tumour of the caecum	Carcinoid tumours	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.241	0.286	3.894	11.557	6.607	11.557	0.01	0.946596	0.21591751
Infliximab	Carcinoid tumour of the small bowel	Carcinoid tumours	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.296	0.298	4.081	22.51	12.12	22.51	0.0004987	0.946596	0.2592826
Infliximab	Carcinoid tumour of the stomach	Carcinoid tumours	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	3	25	22499	2983628	2.63	1.004	6.027	18.786	29.87	18.789	4.619e-8	1.71463043	0.96698385
Infliximab	Carcinoid tumour pulmonary	Carcinoid tumours	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	2	27	22500	2983626	1.602	0.519	4.026	4.737	5.266	4.737	0.022	1.29069204	0.47125285
Infliximab	Carcinoma in situ	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	1	35	22501	2983618	0.905	0.209	2.825	1.798	0.334	1.798	0.563	0.64491541	-0.0998203
Infliximab	Carcinoma in situ of skin	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	1	6	22501	2983647	1.251	0.288	3.927	12.899	7.233	12.899	0.007	0.91547736	0.22394323
Infliximab	Cardiac amyloidosis	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	1	31	22501	2983622	0.874	0.202	2.728	1.61	0.225	1.61	0.635	0.67935182	-0.1346749
Infliximab	Cardiac aneurysm	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	2	178	22500	2983475	0.764	0.247	1.914	0.918	0.014	0.918	0.904	0.34300056	-0.2691875
Infliximab	Cardiac arrest	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	129	25895	22373	2957758	0.732	0.632	0.844	0.729	12.853	0.728	0.0003369	-0.6142664	-0.3119748
Infliximab	Cardiac assistance device user	Disability issues	Lifestyle issues	SocCi	1968-2006	1	1	22501	2983652	1.34	0.307	4.237	99.454	23.309	99.454	0.00000138	0.967721	0.29266961
Infliximab	Cardiac death	Death and sudden death	Fatal outcomes	Genrl	1968-2006	1	93	22501	2983560	0.529	0.122	1.652	0.56	0.333	0.56	0.564	0.22051265	-0.6367668
Infliximab	Cardiac disorder	Cardiac disorders NEC	Cardiac disorder signs and symptoms	Card	1968-2006	97	11888	22405	2971765	0.666	0.562	0.784	0.662	16.595	0.66	0.00004627	0.09489893	-0.4064656
Infliximab	Cardiac enzymes increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	7	566	22495	2983087	0.896	0.475	1.57	0.963	0.01	0.963	0.922	0.5858697	-0.1098149
Infliximab	Cardiac failure	Heart failures NEC	Heart failures	Card	1968-2006	152	14368	22350	2969285	1.074	0.939	1.225	1.081	0.913	1.082	0.339	0.46234012	0.07139
Infliximab	Cardiac failure acute	Heart failures NEC	Heart failures	Card	1968-2006	5	404	22497	2983249	0.64	0.304	1.222	0.663	0.844	0.663	0.358	0.55191826	-0.4462871
Infliximab	Cardiac failure congestive	Heart failures NEC	Heart failures	Card	1968-2006	312	16196	22190	2967457	1.724	1.57	1.891	1.767	99.98	1.782	1.539e-23	1.31054307	0.54464717
Infliximab	Cardiac failure high output	Heart failures NEC	Heart failures	Card	1968-2006	1	23	22501	2983630	1.047	0.242	3.273	3.153	1.291	3.154	0.256	0.75079293	0.04592893
Infliximab	Cardiac fibrillation	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	3	299	22499	2983354	0.698	0.271	1.543	0.762	0.217	0.762	0.642	0.28389492	-0.3595362
Infliximab	Cardiac flutter	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	2	400	22500	2983253	0.279	0.09	0.7	0.25	4.482	0.25	0.034	-0.4293462	-1.2765435
Infliximab	Cardiac hypertrophy	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	2	81	22500	2983572	1.092	0.354	2.739	1.707	0.566	1.707	0.452	0.8769495	0.08801088
Infliximab	Cardiac imaging procedure abnormal	Cardiac imaging procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	2	22501	2983651	1.29	0.297	4.061	19.927	11.301	19.927	0.001	0.95711984	0.25464222
Infliximab	Cardiac index decreased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	46	22501	2983607	0.883	0.204	2.756	1.656	0.253	1.656	0.615	0.5542459	-0.1244301
Infliximab	Cardiac murmur	Cardiac auscultatory investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	25	2904	22477	2980749	0.813	0.581	1.113	0.822	0.938	0.822	0.333	0.16937953	-0.2070242
Infliximab	Cardiac myxoma	Cardiovascular neoplasms benign	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	1	23	22501	2983630	1.043	0.241	3.258	3.089	1.243	3.089	0.265	0.75079293	0.04210118
Infliximab	Cardiac operation	Cardiac therapeutic procedures NEC	Cardiac therapeutic procedures	Surg	1968-2006	8	381	22494	2983272	0.914	0.505	1.552	0.977	0.004	0.977	0.947	1.19107391	-0.0899247
Infliximab	Cardiac output decreased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	213	22500	2983440	0.711	0.23	1.783	0.826	0.073	0.826	0.786	0.19033444	-0.3410828
Infliximab	Cardiac pacemaker insertion	Cardiac pacemaker therapeutic procedures	Cardiac therapeutic procedures	Surg	1968-2006	6	614	22496	2983039	0.787	0.397	1.434	0.836	0.187	0.836	0.665	0.30029571	-0.239527
Infliximab	Cardiac pacemaker malfunction	Device malfunction events	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	83	22500	2983570	1.005	0.326	2.52	1.466	0.278	1.466	0.598	0.86368809	0.00498754
Infliximab	Cardiac pacemaker revision	Cardiac pacemaker therapeutic procedures	Cardiac therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.319	0.303	4.163	26.456	16.845	26.456	0.00004056	0.967721	0.27687387
Infliximab	Cardiac procedure complication	Cardiac and vascular procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	155	22501	2983498	0.421	0.097	1.315	0.396	0.91	0.396	0.34	-0.1270848	-0.8651224
Infliximab	Cardiac sarcoidosis	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	1	4	22501	2983649	1.272	0.293	3.998	17.413	9.101	17.413	0.003	0.93614837	0.24059046
Infliximab	Cardiac stress test abnormal	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	6	151	22496	2983502	1.795	0.906	3.27	2.485	4.942	2.485	0.026	1.67529773	0.58500502
Infliximab	Cardiac tamponade	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	20	696	22482	2982957	1.904	1.307	2.699	2.131	11.329	2.132	0.001	1.71223171	0.64395694
Infliximab	Cardiac valve disease	Cardiac valve disorders NEC	Cardiac valve disorders	Card	1968-2006	16	5707	22486	2977946	0.533	0.35	0.784	0.53	6.623	0.529	0.01	-1.3802618	-0.6292339
Infliximab	Cardiac valve vegetation	Cardiac valve disorders NEC	Cardiac valve disorders	Card	1968-2006	2	53	22500	2983600	1.261	0.409	3.162	2.367	1.443	2.367	0.23	1.07667128	0.23190506
Infliximab	Cardiac ventricular disorder	Cardiac disorders NEC	Cardiac disorder signs and symptoms	Card	1968-2006	2	65	22500	2983588	1.188	0.385	2.978	2.033	1.006	2.033	0.316	0.98767138	0.17227122
Infliximab	Cardio-respiratory arrest	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	71	7467	22431	2976186	0.653	0.535	0.79	0.649	13.407	0.648	0.0002507	0.31188263	-0.4261781
Infliximab	Cardio-respiratory distress	Heart failures NEC	Heart failures	Card	1968-2006	3	24	22499	2983629	2.125	0.824	4.721	6.244	11.24	6.245	0.001	1.72358648	0.7537718
Infliximab	Cardioactive drug level	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	2	2	22500	2983651	2.208	0.69	5.895	83.325	45.384	83.549	1.62e-11	1.53155852	0.79208713
Infliximab	Cardioactive drug level decreased	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	1	36	22501	2983617	0.907	0.21	2.833	1.804	0.342	1.804	0.559	0.63643321	-0.0976128
Infliximab	Cardiogenic shock	Heart failures NEC	Heart failures	Card	1968-2006	26	1459	22476	2982194	1.311	0.943	1.785	1.374	2.556	1.375	0.11	1.14453849	0.2707902
Infliximab	Cardiolipin antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	18	118	22484	2983535	5.436	3.613	8.058	9.356	106.265	9.365	6.451e-25	3.22409938	1.6930435
Infliximab	Cardiomegaly	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	99	5805	22403	2977848	1.443	1.22	1.697	1.477	14.698	1.48	0.0001261	1.13217135	0.36672428
Infliximab	Cardiomyopathy	Cardiomyopathies	Myocardial disorders	Card	1968-2006	58	3866	22444	2979787	1.383	1.11	1.706	1.423	7.039	1.424	0.008	0.94524652	0.32425505
Infliximab	Cardiomyopathy alcoholic	Cardiomyopathies	Myocardial disorders	Card	1968-2006	1	22	22501	2983631	1.076	0.249	3.362	3.362	1.618	3.362	0.203	0.75997701	0.07325046
Infliximab	Cardiopulmonary failure	Heart failures NEC	Heart failures	Card	1968-2006	9	476	22493	2983177	0.913	0.521	1.509	0.968	0.009	0.968	0.923	1.09972934	-0.0910194
Infliximab	Cardiotoxicity	Cardiac disorders NEC	Cardiac disorder signs and symptoms	Card	1968-2006	1	259	22501	2983394	0.246	0.057	0.768	0.196	3.324	0.196	0.068	-0.56981	-1.4024237
Infliximab	Cardiovascular disorder	Cardiac disorders NEC	Cardiac disorder signs and symptoms	Card	1968-2006	24	13241	22478	2970412	0.211	0.15	0.291	0.205	74.431	0.205	6.279e-18	-2.0214706	-1.5558971
Infliximab	Cardiovascular function test abnormal	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	21	22500	2983632	1.76	0.569	4.436	7.706	8.89	7.706	0.003	1.34493959	0.56531381
Infliximab	Carotid artery aneurysm	Central nervous system aneurysms	Central nervous system vascular disorders	Nerv	1968-2006	2	65	22500	2983588	1.042	0.338	2.613	1.553	0.389	1.553	0.533	0.98767138	0.04114194
Infliximab	Carotid artery atheroma	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	119	22501	2983534	0.539	0.125	1.683	0.58	0.296	0.58	0.586	0.06444279	-0.6180397
Infliximab	Carotid artery disease	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	3	340	22499	2983313	0.583	0.226	1.288	0.605	0.754	0.605	0.385	0.15409877	-0.5395681
Infliximab	Carotid artery occlusion	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	8	537	22494	2983116	0.828	0.457	1.406	0.871	0.148	0.871	0.701	0.81414133	-0.1887421
Infliximab	Carotid artery stenosis	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	19	1314	22483	2982339	1.182	0.804	1.69	1.243	0.871	1.244	0.351	0.85392093	0.16720792
Infliximab	Carotid artery thrombosis	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	152	22499	2983501	1.257	0.488	2.78	1.824	1.063	1.824	0.303	0.87790655	0.22872793
Infliximab	Carotid endarterectomy	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	1	26	22501	2983627	1.001	0.231	3.126	2.587	0.872	2.587	0.35	0.72358631	0.0009995
Infliximab	Carpal tunnel decompression	Peripheral nerve therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	1	65	22501	2983588	0.756	0.175	2.36	1.115	0.012	1.115	0.913	0.40991926	-0.2797139
Infliximab	Carpal tunnel syndrome	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	33	1120	22469	2982533	1.839	1.373	2.422	1.97	15.117	1.972	0.000101	1.80846122	0.60922195
Infliximab	Cartilage injury	Limb injuries NEC (incl traumatic amputation)	Bone and joint injuries	Inj&P	1968-2006	2	260	22500	2983393	0.489	0.159	1.226	0.492	1.036	0.492	0.309	0.00783954	-0.7153928
Infliximab	Cartilage operation	Cartilage therapeutic procedures	Soft tissue therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.313	0.302	4.138	41.106	15.232	41.106	0.00009507	0.967721	0.2723146
Infliximab	Cat scratch disease	Bartonella infections	Rickettsial infectious disorders	Infec	1968-2006	1	16	22501	2983637	1.102	0.255	3.444	3.746	1.992	3.746	0.158	0.81634411	0.09712671
Infliximab	Cataract	Cataract conditions	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	33	5442	22469	2978211	0.636	0.475	0.838	0.634	6.85	0.633	0.009	-0.3177109	-0.4525567
Infliximab	Cataract congenital	Lens disorders congenital	Eye disorders congenital	Cong	1968-2006	1	28	22501	2983625	0.994	0.23	3.106	2.421	0.823	2.422	0.364	0.70572945	-0.0060181
Infliximab	Cataract operation	Lens therapeutic procedures	Eye therapeutic procedures	Surg	1968-2006	9	571	22493	2983082	1.193	0.681	1.972	1.327	0.69	1.327	0.406	0.89357324	0.17647114
Infliximab	Catheter bacteraemia	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	1	12	22501	2983641	1.15	0.266	3.598	4.793	2.934	4.793	0.087	0.85518395	0.13976194
Infliximab	Catheter related complication	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	14	745	22488	2982908	0.917	0.584	1.384	0.951	0.034	0.951	0.853	1.15555125	-0.0866478
Infliximab	Catheter related infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	21	786	22481	2982867	1.298	0.899	1.826	1.372	2.044	1.372	0.153	1.6325041	0.26082462
Infliximab	Catheter sepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	15	111	22487	2983542	4.746	3.053	7.176	7.896	76.505	7.903	2.197e-18	3.03070694	1.55730216
Infliximab	Catheter site cellulitis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	21	22501	2983632	0.978	0.226	3.055	2.339	0.713	2.34	0.398	0.76921993	-0.0222456
Infliximab	Catheter site erythema	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	56	22501	2983597	0.737	0.17	2.299	1.053	0.003	1.053	0.959	0.47648884	-0.3051674
Infliximab	Catheter site haemorrhage	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	5	203	22497	2983450	1.117	0.53	2.134	1.324	0.378	1.325	0.539	1.21960371	0.11064652
Infliximab	Catheter site infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	3	104	22499	2983549	1.153	0.448	2.549	1.57	0.606	1.57	0.436	1.14036908	0.14236724
Infliximab	Catheter site inflammation	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	14	22501	2983639	1.057	0.244	3.302	3.218	1.399	3.219	0.237	0.83563334	0.05543471
Infliximab	Catheter site pain	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	59	22501	2983594	0.663	0.153	2.068	0.843	0.028	0.843	0.867	0.453956	-0.4109803
Infliximab	Catheter site phlebitis	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	6	22501	2983647	1.238	0.286	3.885	10.193	6.363	10.193	0.012	0.91547736	0.21349717
Infliximab	Catheterisation cardiac	Cardiac imaging procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	11	155	22491	2983498	3.014	1.813	4.776	4.483	25.975	4.485	3.459e-7	2.4088987	1.1032681
Infliximab	Cauda equina syndrome	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	95	22501	2983558	0.525	0.121	1.64	0.555	0.348	0.555	0.555	0.20788933	-0.644357
Infliximab	Cavernous sinus thrombosis	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	34	22500	2983619	1.508	0.488	3.787	3.827	3.813	3.827	0.051	1.22987801	0.41078427
Infliximab	Cell-mediated immune deficiency	Immunodeficiency disorders NEC	Immunodeficiency syndromes	Immun	1968-2006	1	10	22501	2983643	1.233	0.285	3.869	9.121	6.033	9.121	0.014	0.87500312	0.20945022
Infliximab	Cellulitis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	210	6079	22292	2977574	2.938	2.62	3.286	3.136	283.405	3.157	0	2.12009821	1.07772908
Infliximab	Cellulitis gangrenous	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	11	22500	2983642	1.879	0.606	4.759	11.214	13.402	11.216	0.0002513	1.4401465	0.63073972
Infliximab	Cellulitis orbital	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	34	22501	2983619	0.855	0.198	2.67	1.532	0.173	1.532	0.678	0.65344776	-0.1566538
Infliximab	Cellulitis pasteurella	Pasteurella infections	Bacterial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.306	0.3	4.114	34.378	13.877	34.378	0.0001951	0.967721	0.26696903
Infliximab	Cellulitis staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	6	44	22496	2983609	3.413	1.71	6.327	8.653	33.573	8.655	6.864e-9	2.33783125	1.22759167
Infliximab	Cellulitis streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	3	17	22499	2983636	2.297	0.889	5.128	8.579	15.877	8.582	0.0000676	1.78788545	0.83160392
Infliximab	Central line infection	Vascular infections	Infections - pathogen class unspecified	Infec	1968-2006	9	223	22493	2983430	1.933	1.103	3.196	2.449	7.246	2.45	0.007	1.85859956	0.6590732
Infliximab	Central nervous system abscess	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	9	22501	2983644	1.197	0.276	3.75	6.663	4.344	6.664	0.037	0.88501574	0.17981843
Infliximab	Central nervous system infection	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	4	40	22498	2983613	2.189	0.955	4.458	4.659	10.011	4.66	0.002	1.90034276	0.78344482
Infliximab	Central nervous system inflammation	Central nervous system inflammatory disorders NEC	Central nervous system infections and inflammations	Nerv	1968-2006	3	11	22499	2983642	2.686	1.021	6.213	15.842	33.107	15.85	8.724e-9	1.84537563	0.9880531
Infliximab	Central nervous system lesion	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	2	57	22500	2983596	1.163	0.377	2.916	1.959	0.882	1.959	0.348	1.04639056	0.15100287
Infliximab	Central nervous system lymphoma	Lymphomas unspecified NEC	Lymphomas NEC	Neopl	1968-2006	7	102	22495	2983551	2.275	1.206	3.989	3.405	10.818	3.406	0.001	2.12842585	0.82198005
Infliximab	Central nervous system neoplasm	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	432	22501	2983221	0.793	0.184	2.476	1.253	0.048	1.253	0.826	-1.0954994	-0.2319321
Infliximab	Central venous catheterisation	Venous therapeutic procedures	Vascular therapeutic procedures	Surg	1968-2006	1	8	22501	2983645	1.205	0.278	3.776	8.098	4.675	8.098	0.031	0.89509832	0.18647957
Infliximab	Central venous pressure increased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	56	22501	2983597	0.866	0.2	2.704	1.573	0.201	1.573	0.654	0.47648884	-0.1438704
Infliximab	Cerebellar ataxia	Cerebellar coordination and balance disturbances	Neurological disorders NEC	Nerv	1968-2006	2	296	22500	2983357	0.801	0.26	2.008	0.989	0	0.989	0.988	-0.1178317	-0.2218943
Infliximab	Cerebellar atrophy	Structural brain disorders NEC	Structural brain disorders	Nerv	1968-2006	2	155	22500	2983498	0.757	0.245	1.898	0.906	0.019	0.906	0.89	0.45290425	-0.278392
Infliximab	Cerebellar haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	91	22499	2983562	1.319	0.512	2.916	1.96	1.388	1.96	0.239	1.22051305	0.27687387
Infliximab	Cerebellar infarction	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	5	336	22497	2983317	0.868	0.412	1.659	0.956	0.01	0.956	0.921	0.74512984	-0.1415636
Infliximab	Cerebellar syndrome	Cerebellar coordination and balance disturbances	Neurological disorders NEC	Nerv	1968-2006	2	781	22500	2982872	0.34	0.11	0.851	0.315	2.976	0.315	0.085	-1.2046721	-1.0788097
Infliximab	Cerebellar tumour	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	27	22501	2983626	1.007	0.233	3.147	2.658	0.926	2.658	0.336	0.71463025	0.00697561
Infliximab	Cerebral arteriosclerosis	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	114	22501	2983539	0.532	0.123	1.661	0.57	0.321	0.57	0.571	0.0931742	-0.6311118
Infliximab	Cerebral artery embolism	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	501	22499	2983152	0.786	0.305	1.738	0.893	0.037	0.893	0.848	-0.2658553	-0.2407985
Infliximab	Cerebral artery occlusion	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	402	22499	2983251	0.474	0.184	1.047	0.47	1.756	0.47	0.185	-0.0223681	-0.746548
Infliximab	Cerebral artery stenosis	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	79	22501	2983574	0.733	0.169	2.287	1.041	0.002	1.041	0.969	0.31211031	-0.3106096
Infliximab	Cerebral artery thrombosis	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	3	571	22499	2983082	1.004	0.39	2.22	1.27	0.165	1.27	0.684	-0.4161727	0.00399202
Infliximab	Cerebral aspergillosis	Aspergillus infections	Fungal infectious disorders	Infec	1968-2006	1	26	22501	2983627	0.945	0.219	2.951	2.069	0.515	2.069	0.473	0.72358631	-0.0565704
Infliximab	Cerebral atrophy	Structural brain disorders NEC	Structural brain disorders	Nerv	1968-2006	16	898	22486	2982755	0.965	0.634	1.422	1.002	0	1.002	0.995	1.10504612	-0.0356272
Infliximab	Cerebral cyst	Nervous system neoplasms benign NEC	Nervous system neoplasms benign	Nerv	1968-2006	2	112	22500	2983541	0.844	0.274	2.115	1.075	0.01	1.075	0.919	0.6839525	-0.1696028
Infliximab	Cerebral disorder	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	5	326	22497	2983327	0.876	0.415	1.672	0.966	0.006	0.966	0.939	0.77585792	-0.1323892
Infliximab	Cerebral fungal infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	2	21	22500	2983632	1.642	0.531	4.13	5.103	6	5.104	0.014	1.34493959	0.49591501
Infliximab	Cerebral haematoma	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	2	225	22500	2983428	0.542	0.176	1.36	0.565	0.665	0.565	0.415	0.14150116	-0.6124893
Infliximab	Cerebral haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	37	2768	22465	2980885	0.685	0.52	0.889	0.684	5.307	0.684	0.021	0.77656091	-0.3783364
Infliximab	Cerebral haemorrhage neonatal	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	4	80	22498	2983573	1.93	0.842	3.926	3.399	6.409	3.4	0.011	1.60726953	0.65752
Infliximab	Cerebral infarction	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	48	4934	22454	2978719	0.856	0.672	1.078	0.862	1.045	0.862	0.307	0.34251929	-0.1554849
Infliximab	Cerebral infarction foetal	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	1	2	22501	2983651	1.319	0.303	4.163	31.163	16.668	31.163	0.00004454	0.95711984	0.27687387
Infliximab	Cerebral ischaemia	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	22	3051	22480	2980602	0.947	0.662	1.322	0.971	0.019	0.971	0.891	-0.0738569	-0.0544562
Infliximab	Cerebral malaria	Plasmodia infections	Protozoal infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.365	0.311	4.33	62.802	37.939	62.802	7.3e-10	0.95711984	0.31115443
Infliximab	Cerebral thrombosis	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	2	320	22500	2983333	0.354	0.115	0.889	0.331	2.698	0.331	0.1	-0.1959171	-1.0384584
Infliximab	Cerebral toxoplasmosis	Toxoplasma infections	Protozoal infectious disorders	Infec	1968-2006	2	55	22500	2983598	1.229	0.398	3.082	2.183	1.244	2.183	0.265	1.06145149	0.20620083
Infliximab	Cerebral venous thrombosis	Cerebrovascular venous and sinus thrombosis	Central nervous system vascular disorders	Nerv	1968-2006	4	188	22498	2983465	1.187	0.518	2.412	1.508	0.662	1.508	0.416	1.02578498	0.17142912
Infliximab	Cerebral ventricle dilatation	Structural brain disorders NEC	Structural brain disorders	Nerv	1968-2006	2	186	22500	2983467	0.54	0.175	1.354	0.56	0.68	0.56	0.409	0.3066543	-0.6161861
Infliximab	Cerebrovascular accident	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	206	33908	22296	2949745	0.402	0.358	0.45	0.396	194.517	0.39	3.285e-44	-0.3358338	-0.9113032
Infliximab	Cerebrovascular disorder	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	17	2137	22485	2981516	0.796	0.529	1.16	0.811	0.735	0.811	0.391	0.06015895	-0.2281561
Infliximab	Cerebrovascular spasm	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	83	22501	2983570	0.661	0.153	2.062	0.841	0.03	0.841	0.863	0.28534087	-0.4140014
Infliximab	Cerebrovascular stenosis	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	40	22501	2983613	0.794	0.184	2.478	1.253	0.05	1.253	0.823	0.60299444	-0.2306718
Infliximab	Cervical cord compression	Cervical spinal cord and nerve root disorders	Spinal cord and nerve root disorders	Nerv	1968-2006	2	27	22500	2983626	1.576	0.51	3.96	4.336	4.808	4.337	0.028	1.29069204	0.45488999
Infliximab	Cervical cyst	Cervix neoplasms	Cervix disorders (excl infections and inflammations)	Repro	1968-2006	1	26	22501	2983627	0.958	0.222	2.991	2.169	0.59	2.169	0.443	0.72358631	-0.0429075
Infliximab	Cervical dysplasia	Cervix disorders NEC	Cervix disorders (excl infections and inflammations)	Repro	1968-2006	14	183	22488	2983470	3.366	2.144	5.087	4.813	37.293	4.818	1.017e-9	2.58876163	1.2137251
Infliximab	Cervical gland tuberculosis				1968-2006	10	4	22492	2983649	27.74	15.423	46.397	212.777	316.604	212.922	0	3.30480759	3.32287541
Infliximab	Cervical myelopathy	Cervical spinal cord and nerve root disorders	Spinal cord and nerve root disorders	Nerv	1968-2006	3	62	22499	2983591	1.608	0.625	3.557	2.886	3.551	2.886	0.06	1.41716634	0.47499117
Infliximab	Cervical polyp	Cervix neoplasms	Cervix disorders (excl infections and inflammations)	Repro	1968-2006	1	84	22501	2983569	0.553	0.128	1.727	0.604	0.251	0.604	0.616	0.2787254	-0.5923973
Infliximab	Cervical spinal stenosis	Spine and neck deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	8	128	22494	2983525	2.758	1.521	4.689	4.377	18.729	4.379	0.00001507	2.14609442	1.01450578
Infliximab	Cervical vertebral fracture	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	7	119	22495	2983534	2.226	1.18	3.904	3.249	10.163	3.25	0.001	2.03070504	0.80020625
Infliximab	Cervicitis	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	7	425	22495	2983228	2.472	1.31	4.336	3.958	13.67	3.96	0.0002179	0.90705181	0.90502754
Infliximab	Cervicitis human papilloma virus	Papilloma viral infections	Viral infectious disorders	Infec	1968-2006	1	4	22501	2983649	1.255	0.29	3.939	12.101	7.537	12.101	0.006	0.93614837	0.22713557
Infliximab	Cervicobrachial syndrome	Cervical spinal cord and nerve root disorders	Spinal cord and nerve root disorders	Nerv	1968-2006	4	119	22498	2983534	1.63	0.712	3.313	2.548	3.387	2.548	0.066	1.36940339	0.48858001
Infliximab	Cervix carcinoma	Cervix neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	18	479	22484	2983174	3.125	2.101	4.51	4.005	37.109	4.009	1.117e-9	1.99800786	1.13943428
Infliximab	Cervix carcinoma recurrent	Cervix neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	16	22500	2983637	1.693	0.548	4.263	6.197	7.166	6.197	0.007	1.3917579	0.5265021
Infliximab	Cervix carcinoma stage 0	Cervix neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	4	165	22498	2983488	2.085	0.91	4.244	4.16	8.455	4.162	0.004	1.13148638	0.73476886
Infliximab	Cervix carcinoma stage III	Cervix neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	8	22500	2983645	1.919	0.618	4.872	13.122	15.504	13.124	0.00008235	1.46997828	0.65180422
Infliximab	Cervix disorder	Cervix disorders NEC	Cervix disorders (excl infections and inflammations)	Repro	1968-2006	3	1780	22499	2981873	0.987	0.383	2.181	1.235	0.13	1.235	0.719	-1.8543068	-0.0130852
Infliximab	Cervix operation	Cervix therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	2	2	22500	2983651	2.17	0.683	5.724	58.431	39.697	58.431	2.966e-10	1.53155852	0.77472717
Infliximab	Change of bowel habit	Gastrointestinal dyskinetic disorders	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	4	401	22498	2983252	0.714	0.312	1.451	0.766	0.28	0.766	0.597	0.29956033	-0.3368723
Infliximab	Chapped lips	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	257	22501	2983396	0.259	0.06	0.809	0.205	3.016	0.205	0.082	-0.5624595	-1.3509272
Infliximab	Cheilitis	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	1468	22501	2982185	0.123	0.028	0.384	0.088	9.512	0.088	0.002	-2.5960202	-2.0955709
Infliximab	Cheilosis	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	4	22501	2983649	1.251	0.288	3.926	9.678	7.243	9.679	0.007	0.93614837	0.22394323
Infliximab	Chemical poisoning	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	1	79	22501	2983574	0.701	0.162	2.189	0.948	0.003	0.948	0.958	0.31211031	-0.3552474
Infliximab	Chemotherapy neurotoxicity attenuation	Chemotherapies	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	1	22501	2983652	1.386	0.315	4.417	117.488	67.546	117.488	2.059e-16	0.967721	0.3264219
Infliximab	Chest X-ray abnormal	Respiratory tract and thoracic imaging procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	69	1705	22433	2981948	2.934	2.4	3.56	3.217	97.795	3.226	4.639e-23	2.28180087	1.07636668
Infliximab	Chest discomfort	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	368	7984	22134	2975669	2.874	2.636	3.128	3.02	470.634	3.055	0	2.52369255	1.05570479
Infliximab	Chest pain	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	681	58318	21821	2925335	1.459	1.37	1.554	1.478	104.063	1.494	1.96e-24	0.5843675	0.37775127
Infliximab	Chest wall abscess	Muscle and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	3	13	22499	2983640	2.538	0.974	5.751	13.617	25.257	13.618	5.017e-7	1.8259566	0.93137637
Infliximab	Chest wall mass	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	13	22501	2983640	1.146	0.265	3.585	4.699	2.837	4.699	0.092	0.84537553	0.13627762
Infliximab	Cheyne-Stokes respiration	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	2	135	22500	2983518	0.948	0.307	2.376	1.303	0.141	1.303	0.707	0.55578852	-0.0534008
Infliximab	Chillblains	Conditions caused by cold	Injuries by physical agents	Inj&P	1968-2006	3	21	22499	2983632	2.289	0.886	5.108	8.814	15.591	8.816	0.00007865	1.75079308	0.82811504
Infliximab	Chills	Body temperature perception	Body temperature conditions	Genrl	1968-2006	540	22591	21962	2961062	2.622	2.442	2.813	2.732	566.095	2.78	0	1.61355395	0.96393739
Infliximab	Chlamydial infection	Chlamydial infections	Chlamydial infectious disorders	Infec	1968-2006	4	87	22498	2983566	1.711	0.747	3.477	2.697	4.108	2.697	0.043	1.56158582	0.53707799
Infliximab	Chloroma	Leukaemias myeloid NEC	Leukaemias	Neopl	1968-2006	1	23	22501	2983630	1.036	0.24	3.238	2.904	1.178	2.904	0.278	0.75079293	0.03536714
Infliximab	Choking	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	17	1285	22485	2982368	0.751	0.499	1.094	0.761	1.248	0.761	0.264	0.73275365	-0.2863496
Infliximab	Choking sensation	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	4	387	22498	2983266	0.66	0.288	1.341	0.698	0.524	0.698	0.469	0.33756386	-0.4155154
Infliximab	Cholangitis	Bile duct infections and inflammations	Bile duct disorders	Hepat	1968-2006	17	773	22485	2982880	1.719	1.143	2.505	1.916	7.104	1.917	0.008	1.36931732	0.54174273
Infliximab	Cholangitis acute	Bile duct infections and inflammations	Bile duct disorders	Hepat	1968-2006	3	81	22499	2983572	1.682	0.653	3.721	3.216	4.263	3.216	0.039	1.28534125	0.51998356
Infliximab	Cholangitis sclerosing	Bile duct infections and inflammations	Bile duct disorders	Hepat	1968-2006	7	156	22495	2983497	2.575	1.365	4.519	4.198	15.239	4.199	0.00009474	1.83845582	0.94584953
Infliximab	Cholecystectomy	Biliary tract and gallbladder therapeutic procedures	Hepatobiliary therapeutic procedures	Surg	1968-2006	43	663	22459	2982990	3.605	2.791	4.596	4.304	95.984	4.309	1.158e-22	2.79644179	1.28232177
Infliximab	Cholecystitis	Cholecystitis and cholelithiasis	Gallbladder disorders	Hepat	1968-2006	36	2481	22466	2981172	1.652	1.249	2.152	1.747	11.011	1.748	0.001	0.88703588	0.50198668
Infliximab	Cholecystitis acute	Cholecystitis and cholelithiasis	Gallbladder disorders	Hepat	1968-2006	19	403	22483	2983250	2.552	1.735	3.649	3.08	24.363	3.082	7.979e-7	2.25472489	0.93687737
Infliximab	Cholecystitis chronic	Cholecystitis and cholelithiasis	Gallbladder disorders	Hepat	1968-2006	5	192	22497	2983461	1.401	0.664	2.675	1.82	1.725	1.82	0.189	1.26683092	0.33718627
Infliximab	Cholecystitis infective	Hepatobiliary and spleen infections	Infections - pathogen class unspecified	Infec	1968-2006	1	101	22501	2983552	0.553	0.128	1.726	0.604	0.25	0.604	0.617	0.17066877	-0.5923973
Infliximab	Choledochal cyst	Hepatobiliary neoplasms benign	Hepatobiliary neoplasms	Hepat	1968-2006	1	8	22501	2983645	1.21	0.279	3.793	6.943	4.897	6.943	0.027	0.89509832	0.19062036
Infliximab	Cholelithiasis	Cholecystitis and cholelithiasis	Gallbladder disorders	Hepat	1968-2006	76	5711	22426	2977942	1.142	0.943	1.373	1.159	1.6	1.159	0.206	0.78337928	0.13278111
Infliximab	Cholestasis	Cholestasis and jaundice	Hepatic and hepatobiliary disorders	Hepat	1968-2006	33	2944	22469	2980709	0.782	0.584	1.03	0.787	1.872	0.786	0.171	0.53394716	-0.2459005
Infliximab	Choluria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	1	31	22501	2983622	0.92	0.213	2.872	1.877	0.395	1.877	0.53	0.67935182	-0.0833816
Infliximab	Chondritis	Cartilage disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	1	17	22501	2983636	1.049	0.243	3.279	3.181	1.317	3.181	0.251	0.80679534	0.04783733
Infliximab	Chondrocalcinosis	Crystal arthropathic disorders	Joint disorders	Musc	1968-2006	1	37	22501	2983616	0.957	0.221	2.989	2.12	0.582	2.12	0.445	0.62800058	-0.0439519
Infliximab	Chondrocalcinosis pyrophosphate	Crystal arthropathic disorders	Joint disorders	Musc	1968-2006	5	50	22497	2983603	2.684	1.27	5.151	5.902	17.719	5.903	0.0000256	2.07667171	0.98730822
Infliximab	Chondrolysis	Cartilage disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	1	24	22501	2983629	1.039	0.24	3.247	2.947	1.203	2.947	0.273	0.74166694	0.03825871
Infliximab	Chondromalacia	Joint related disorders NEC	Joint disorders	Musc	1968-2006	1	104	22501	2983549	0.591	0.137	1.846	0.679	0.145	0.679	0.703	0.15241245	-0.5259393
Infliximab	Chondropathy	Cartilage disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	4	230	22498	2983423	0.91	0.397	1.849	1.043	0.007	1.043	0.933	0.85072626	-0.0943107
Infliximab	Chondrosarcoma	Cartilage sarcomas	Skeletal neoplasms malignant and unspecified	Neopl	1968-2006	1	18	22501	2983635	1.064	0.246	3.326	3.206	1.48	3.207	0.224	0.79730935	0.06203539
Infliximab	Chordae tendinae rupture	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	1	14	22501	2983639	1.138	0.263	3.561	5.02	2.679	5.02	0.102	0.83563334	0.12927234
Infliximab	Chorea	Choreiform movements	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	2	237	22500	2983416	0.577	0.187	1.447	0.613	0.483	0.613	0.487	0.09426647	-0.549913
Infliximab	Choreoathetosis	Choreiform movements	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	1141	22501	2982512	0.492	0.114	1.535	0.501	0.491	0.501	0.483	-2.2666226	-0.7092766
Infliximab	Chorioretinal disorder	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	1	55	22501	2983598	0.769	0.178	2.4	1.162	0.022	1.162	0.883	0.48407867	-0.2626643
Infliximab	Chorioretinitis	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	3	53	22499	2983600	2.051	0.796	4.552	5.505	9.68	5.505	0.002	1.48407896	0.71832748
Infliximab	Chorioretinopathy	Choroid and vitreous structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	2	60	22500	2983593	1.321	0.428	3.314	2.609	1.876	2.61	0.171	1.0240899	0.27838903
Infliximab	Choroid melanoma	Ocular melanomas	Ocular neoplasms	Neopl	1968-2006	1	4	22501	2983649	1.304	0.3	4.107	17.858	13.306	17.865	0.0002646	0.93614837	0.26543646
Infliximab	Choroid neoplasm	Ocular neoplasms malignancy unspecified	Ocular neoplasms	Neopl	1968-2006	1	3	22501	2983650	1.315	0.302	4.148	21.212	15.669	21.221	0.00007544	0.946596	0.27383667
Infliximab	Choroidal neovascularisation	Choroid and vitreous haemorrhages and vascular disorders	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	53	22501	2983600	0.808	0.187	2.522	1.311	0.071	1.312	0.79	0.49937916	-0.2131932
Infliximab	Choroiditis	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	2	35	22500	2983618	1.627	0.527	4.092	4.854	5.72	4.854	0.017	1.22139582	0.48673783
Infliximab	Chromatopsia	Visual colour distortions	Vision disorders	Eye	1968-2006	2	423	22500	2983230	0.607	0.197	1.523	0.656	0.351	0.656	0.554	-0.4900175	-0.4992265
Infliximab	Chromaturia	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	11	3638	22491	2980015	0.228	0.137	0.361	0.22	30.565	0.22	3.228e-8	-1.2510744	-1.4784097
Infliximab	Chromoblastomycosis	Cladosporidia infections	Fungal infectious disorders	Infec	1968-2006	1	3	22501	2983650	1.303	0.3	4.103	19.702	13.15	19.702	0.0002875	0.946596	0.2646693
Infliximab	Chromosome abnormality	Chromosomal abnormalities NEC	Chromosomal abnormalities and abnormal gene carriers	Cong	1968-2006	2	488	22500	2983165	0.389	0.126	0.975	0.368	2.132	0.368	0.144	-0.6488555	-0.9441759
Infliximab	Chromosome analysis abnormal	Chromosome analyses	Cytogenetic investigations	Inv	1968-2006	1	115	22501	2983538	0.571	0.132	1.781	0.64	0.199	0.64	0.656	0.08738197	-0.5603661
Infliximab	Chronic fatigue syndrome	Asthenic conditions	General system disorders NEC	Genrl	1968-2006	2	331	22500	2983322	0.429	0.139	1.076	0.417	1.613	0.417	0.204	-0.2303413	-0.8462984
Infliximab	Chronic granulomatous disease	Immune system abnormalities congenital	Immune system disorders congenital	Cong	1968-2006	1	7	22501	2983646	1.211	0.28	3.796	8.499	4.959	8.499	0.026	0.90525186	0.19144646
Infliximab	Chronic hepatitis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	5	215	22497	2983438	1.313	0.623	2.508	1.653	1.222	1.654	0.269	1.16978695	0.2723146
Infliximab	Chronic inflammatory demyelinating polyradiculoneuropathy	Chronic polyneuropathies	Peripheral neuropathies	Nerv	1968-2006	3	38	22499	2983615	2.029	0.787	4.501	5.329	9.23	5.329	0.002	1.60299467	0.70754306
Infliximab	Chronic lymphocytic leukaemia	Leukaemias chronic lymphocytic	Leukaemias	Neopl	1968-2006	23	384	22479	2983269	4.142	2.914	5.754	5.573	75.978	5.578	2.869e-18	2.55725338	1.42117876
Infliximab	Chronic lymphocytic leukaemia stage 0	Leukaemias chronic lymphocytic	Leukaemias	Neopl	1968-2006	1	4	22501	2983649	1.265	0.292	3.975	13.744	8.426	13.744	0.004	0.93614837	0.23507212
Infliximab	Chronic myeloid leukaemia	Leukaemias chronic myeloid	Leukaemias	Neopl	1968-2006	13	441	22489	2983212	2.219	1.391	3.397	2.729	13.275	2.73	0.0002689	1.65934564	0.79705664
Infliximab	Chronic myelomonocytic leukaemia	Myelodysplastic syndromes	Leukaemias	Neopl	1968-2006	2	58	22500	2983595	1.339	0.434	3.359	2.712	2.028	2.712	0.154	1.03891865	0.29192307
Infliximab	Chronic obstructive pulmonary disease	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	171	3797	22331	2979856	2.923	2.574	3.309	3.146	229.579	3.169	0	2.47333971	1.07261049
Infliximab	Chronic pulmonary histoplasmosis	Histoplasma infections	Fungal infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.368	0.312	4.344	1085.895	76.698	1093.547	1.992e-18	0.97840063	0.31334982
Infliximab	Chronic respiratory failure	Respiratory failures (excl neonatal)	Respiratory disorders NEC	Resp	1968-2006	2	51	22500	2983602	1.292	0.419	3.242	2.522	1.669	2.522	0.196	1.09205332	0.25619141
Infliximab	Chronic sinusitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	8	221	22494	2983432	1.853	1.023	3.146	2.371	6.004	2.371	0.014	1.7184849	0.61680595
Infliximab	Chronic tonsillitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	9	22501	2983644	1.207	0.279	3.782	7.382	4.76	7.382	0.029	0.88501574	0.18813794
Infliximab	Circulatory collapse	Circulatory collapse and shock	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	35	4681	22467	2978972	0.484	0.364	0.633	0.48	19.733	0.479	8.904e-6	-0.0251051	-0.7256704
Infliximab	Circumoral oedema	Angioedemas	Angioedema and urticaria	Skin	1968-2006	1	30	22501	2983623	0.876	0.203	2.734	1.639	0.231	1.639	0.63	0.68809089	-0.1323892
Infliximab	Cirrhosis alcoholic	Hepatic fibrosis and cirrhosis	Hepatic and hepatobiliary disorders	Hepat	1968-2006	2	78	22500	2983575	1.126	0.365	2.824	1.824	0.707	1.824	0.401	0.89707299	0.11867153
Infliximab	Citrobacter infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	6	60	22496	2983593	2.853	1.437	5.217	5.469	20.205	5.47	6.958e-6	2.21727499	1.04837107
Infliximab	Clavicle fracture	Upper limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	4	209	22498	2983444	1.07	0.467	2.174	1.303	0.269	1.303	0.604	0.93560263	0.06765865
Infliximab	Clear cell carcinoma of the kidney	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	2	18	22500	2983635	1.782	0.576	4.496	7.239	9.566	7.239	0.002	1.37284789	0.57773633
Infliximab	Clonic convulsion	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	2	225	22500	2983428	0.406	0.132	1.018	0.39	1.901	0.39	0.168	0.14150116	-0.9014021
Infliximab	Clonus	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	3	178	22499	2983475	0.834	0.324	1.843	0.969	0.003	0.969	0.957	0.75344467	-0.1815219
Infliximab	Closed head injury				1968-2006	1	60	22501	2983593	0.713	0.165	2.225	0.981	0	0.981	0.985	0.44652257	-0.3382739
Infliximab	Clostridial infection	Clostridia infections	Bacterial infectious disorders	Infec	1968-2006	23	651	22479	2983002	1.761	1.24	2.442	1.93	9.728	1.931	0.002	1.97804152	0.56588183
Infliximab	Clostridium colitis	Clostridia infections	Bacterial infectious disorders	Infec	1968-2006	41	6841	22461	2976812	1.278	0.984	1.638	1.318	3.043	1.319	0.081	-0.3364602	0.24529636
Infliximab	Clostridium difficile toxin test	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	9	22501	2983644	1.188	0.274	3.721	6.012	4.021	6.012	0.045	0.88501574	0.17227122
Infliximab	Clostridium difficile toxin test positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	58	22501	2983595	0.808	0.187	2.522	1.314	0.07	1.314	0.791	0.46142791	-0.2131932
Infliximab	Clumsiness	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	6	288	22496	2983365	1.197	0.604	2.181	1.405	0.67	1.405	0.413	1.1179971	0.17981843
Infliximab	Cluster headache	Headaches NEC	Headaches	Nerv	1968-2006	3	63	22499	2983590	1.63	0.633	3.606	3.08	3.748	3.08	0.053	1.40991958	0.48858001
Infliximab	Coagulation factor V level decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	169	22499	2983484	1.098	0.427	2.427	1.46	0.412	1.46	0.521	0.79532378	0.09349034
Infliximab	Coagulation factor VII level decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	63	22501	2983590	0.736	0.17	2.296	1.051	0.002	1.051	0.962	0.42444935	-0.3065252
Infliximab	Coagulation factor VIII level abnormal	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	8	22501	2983645	1.213	0.28	3.803	8.667	5.042	8.667	0.025	0.89509832	0.19309663
Infliximab	Coagulation factor X level decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	49	22501	2983604	0.831	0.192	2.593	1.412	0.113	1.412	0.737	0.53047566	-0.1851255
Infliximab	Coagulation factor XII level decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	7	22501	2983646	1.222	0.282	3.833	7.726	5.48	7.726	0.019	0.90525186	0.20048886
Infliximab	Coagulation factor decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	118	22501	2983535	0.594	0.137	1.854	0.69	0.139	0.69	0.709	0.07014349	-0.520876
Infliximab	Coagulation time prolonged	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	1009	22499	2982644	0.593	0.23	1.31	0.617	0.69	0.617	0.406	-1.1114856	-0.5225609
Infliximab	Coagulopathy	Coagulopathies	Coagulopathies and bleeding diatheses (excl thrombocytopenic)	Blood	1968-2006	44	5680	22458	2977973	0.985	0.765	1.252	0.998	0	0.998	0.991	0.02389492	-0.0151136
Infliximab	Coccidioidomycosis	Coccidioides infections	Fungal infectious disorders	Infec	1968-2006	48	60	22454	2983593	20.979	16.428	26.471	44.515	964.993	44.646	0	4.74910433	3.04352194
Infliximab	Coeliac disease	Malabsorption syndromes	Malabsorption conditions	Gastr	1968-2006	2	295	22500	2983358	0.416	0.135	1.042	0.4	1.774	0.4	0.183	-0.1144847	-0.87707
Infliximab	Cognitive deterioration				1968-2006	1	203	22501	2983450	0.392	0.091	1.223	0.356	1.145	0.356	0.284	-0.3483647	-0.9364934
Infliximab	Cognitive disorder	Mental impairment (excl dementia and memory loss)	Mental impairment disorders	Nerv	1968-2006	4	2291	22498	2981362	0.13	0.057	0.264	0.116	26.671	0.116	2.412e-7	-1.8742024	-2.0402208
Infliximab	Cold agglutinins positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	46	22501	2983607	0.918	0.212	2.867	1.851	0.387	1.851	0.534	0.5542459	-0.0855579
Infliximab	Cold sweat	Apocrine and eccrine gland disorders	Skin appendage conditions	Skin	1968-2006	34	2367	22468	2981286	0.995	0.746	1.305	1.013	0.006	1.013	0.939	0.87148171	-0.0050125
Infliximab	Colectomy	Large intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	20	164	22482	2983489	5.483	3.727	7.945	9.06	113.908	9.066	1.365e-26	3.13207299	1.7016524
Infliximab	Colectomy total	Large intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	18	22501	2983635	1.054	0.244	3.295	3.12	1.369	3.12	0.242	0.79730935	0.05259245
Infliximab	Colitis	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	60	5458	22442	2978195	1.454	1.172	1.788	1.5	9.647	1.502	0.002	0.51453687	0.37431838
Infliximab	Colitis collagenous	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	2	69	22500	2983584	0.902	0.292	2.262	1.204	0.067	1.204	0.796	0.95918425	-0.1031408
Infliximab	Colitis erosive	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	1	11	22501	2983642	1.102	0.255	3.445	3.798	2.006	3.798	0.157	0.86505951	0.09712671
Infliximab	Colitis ischaemic	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	22	1138	22480	2982515	1.06	0.741	1.48	1.096	0.183	1.097	0.669	1.23672416	0.05826891
Infliximab	Colitis ulcerative	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	49	1890	22453	2981763	2.362	1.86	2.967	2.562	43.891	2.566	3.471e-11	1.67660202	0.85950872
Infliximab	Collagen disorder	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	1	192	22501	2983461	0.5	0.115	1.559	0.518	0.456	0.518	0.5	-0.3005686	-0.6931472
Infliximab	Collapse of lung	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	13	510	22489	2983143	1.408	0.882	2.155	1.556	2.472	1.556	0.116	1.49913082	0.34217026
Infliximab	Colon adenoma	Lower gastrointestinal neoplasms benign	Gastrointestinal neoplasms benign	Neopl	1968-2006	4	109	22498	2983544	1.475	0.644	2.997	2.12	2.224	2.121	0.136	1.42675766	0.38865799
Infliximab	Colon cancer	Colonic neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	88	1107	22414	2982546	4.33	3.624	5.141	4.984	250.106	5.001	0	3.1503921	1.46556754
Infliximab	Colon cancer metastatic	Colonic neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	14	126	22488	2983527	3.871	2.464	5.864	5.915	49.788	5.92	1.713e-12	2.86181149	1.35351287
Infliximab	Colon cancer recurrent	Colonic neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	3	35	22499	2983618	1.97	0.765	4.368	5.048	8.206	5.049	0.004	1.6280008	0.67803354
Infliximab	Colon cancer stage III	Colonic neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	28	22501	2983625	0.907	0.21	2.833	1.825	0.345	1.825	0.557	0.70572945	-0.0976128
Infliximab	Colon cancer stage IV	Colonic neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	8	71	22494	2983582	3.052	1.682	5.196	5.342	24.361	5.344	7.985e-7	2.48880727	1.11579711
Infliximab	Colon neoplasm	Colorectal and anal neoplasms malignancy unspecified	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	8	83	22494	2983570	3.494	1.922	5.981	6.604	33.9	6.606	5.803e-9	2.40958352	1.25104721
Infliximab	Colon operation	Large intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	4	48	22498	2983605	2.112	0.921	4.299	4.304	8.826	4.305	0.003	1.83677215	0.74763537
Infliximab	Colonic fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	6	39	22496	2983614	3.43	1.718	6.364	8.755	34.149	8.757	5.104e-9	2.37766865	1.23256026
Infliximab	Colonic haematoma	Intestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	1	11	22501	2983642	1.295	0.298	4.076	15.169	11.793	15.169	0.001	0.86505951	0.2585107
Infliximab	Colonic obstruction	Large intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	8	148	22494	2983505	2.383	1.315	4.048	3.436	12.792	3.436	0.0003482	2.04284199	0.8683602
Infliximab	Colonic perforation postoperative				1968-2006	1	6	22501	2983647	1.197	0.276	3.75	7.268	4.385	7.268	0.036	0.91547736	0.17981843
Infliximab	Colonic polyp	Benign neoplasms gastrointestinal (excl oral cavity)	Benign neoplasms gastrointestinal	Gastr	1968-2006	21	895	22481	2982758	1.511	1.047	2.125	1.625	4.847	1.626	0.028	1.47426437	0.41277168
Infliximab	Colonic stenosis	Large intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	15	190	22487	2983463	4.299	2.775	6.449	6.713	63.468	6.717	1.63e-15	2.64737178	1.45838244
Infliximab	Colonoscopy	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	4	47	22498	2983606	2.336	1.018	4.764	5.408	12.518	5.409	0.000403	1.84456698	0.84844006
Infliximab	Colonoscopy abnormal	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	5	132	22497	2983521	1.605	0.761	3.066	2.218	3.171	2.218	0.075	1.55578926	0.47312376
Infliximab	Colorectal cancer	Colorectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	8	94	22494	2983559	2.743	1.513	4.664	4.4	18.57	4.401	0.00001637	2.34059525	1.00905221
Infliximab	Colorectal cancer metastatic	Colorectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	75	22500	2983578	0.977	0.317	2.45	1.38	0.206	1.38	0.65	0.91748111	-0.0232686
Infliximab	Colorectal cancer recurrent	Colorectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	6	22501	2983647	1.293	0.298	4.071	17.811	11.709	17.811	0.001	0.91547736	0.2569651
Infliximab	Colorectal cancer stage IV	Colorectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	4	22501	2983649	1.233	0.285	3.868	8.814	6.11	8.814	0.013	0.93614837	0.20945022
Infliximab	Colostomy	Large intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	3	112	22499	2983541	1.284	0.499	2.838	1.899	1.198	1.9	0.274	1.09317465	0.24998021
Infliximab	Colour blindness	Ocular disorders congenital NEC	Eye disorders congenital	Cong	1968-2006	1	313	22501	2983340	0.35	0.081	1.091	0.302	1.569	0.302	0.21	-0.7553181	-1.0498221
Infliximab	Colposuspension	Vaginal therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.33	0.305	4.202	101.391	19.945	101.391	0.00000797	0.967721	0.28517894
Infliximab	Coma	Coma states	Neurological disorders NEC	Nerv	1968-2006	126	23144	22376	2960509	0.613	0.529	0.708	0.609	31.646	0.606	1.85e-8	-0.4861086	-0.4893903
Infliximab	Coma hepatic	Coma states	Neurological disorders NEC	Nerv	1968-2006	3	238	22499	2983415	0.559	0.217	1.237	0.576	0.922	0.576	0.337	0.50158	-0.5816058
Infliximab	Communication disorder	Communications disorders	Communication disorders and disturbances	Psych	1968-2006	3	526	22499	2983127	0.351	0.136	0.776	0.333	3.979	0.333	0.046	-0.3213544	-1.0469691
Infliximab	Compartment syndrome	Myopathies	Muscle disorders	Musc	1968-2006	3	303	22499	2983350	0.603	0.234	1.334	0.633	0.626	0.633	0.429	0.27070541	-0.5058381
Infliximab	Complement factor C3 decreased	Immune response protein analyses NEC	Immunology and allergy investigations	Inv	1968-2006	2	28	22500	2983625	1.445	0.468	3.628	3.318	3.053	3.318	0.081	1.28184581	0.36810932
Infliximab	Complement factor C3 increased	Immune response protein analyses NEC	Immunology and allergy investigations	Inv	1968-2006	3	42	22499	2983611	2.176	0.843	4.839	6.998	12.403	6.999	0.0004287	1.57031335	0.77748833
Infliximab	Complement factor C4 decreased	Immune response protein analyses NEC	Immunology and allergy investigations	Inv	1968-2006	4	31	22498	2983622	2.412	1.051	4.923	5.822	14.011	5.828	0.0001818	1.97537617	0.88045628
Infliximab	Complement factor abnormal	Immune response protein analyses NEC	Immunology and allergy investigations	Inv	1968-2006	1	15	22501	2983638	1.148	0.265	3.591	5.329	2.885	5.33	0.089	0.82595649	0.1380213
Infliximab	Complement factor decreased	Immune response protein analyses NEC	Immunology and allergy investigations	Inv	1968-2006	7	57	22495	2983596	3.769	1.978	6.764	9.633	41.602	9.637	1.119e-10	2.4244503	1.32680971
Infliximab	Completed suicide	Suicidal and self-injurious behaviour	Suicidal and self-injurious behaviours NEC	Psych	1968-2006	17	11871	22485	2971782	0.122	0.081	0.177	0.117	121.966	0.116	2.348e-28	-2.3382831	-2.1037342
Infliximab	Complicated migraine	Migraine headaches	Headaches	Nerv	1968-2006	1	20	22501	2983633	1.061	0.245	3.317	3.287	1.442	3.288	0.23	0.77852244	0.05921186
Infliximab	Complication of pregnancy	Maternal complications of pregnancy NEC	Maternal complications of pregnancy	Preg	1968-2006	3	1120	22499	2982533	1.13	0.439	2.498	1.535	0.522	1.536	0.47	-1.2449619	0.12221763
Infliximab	Complications of bone marrow transplant	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	70	22501	2983583	0.667	0.154	2.083	0.854	0.024	0.854	0.878	0.37422158	-0.4049652
Infliximab	Complications of maternal exposure to therapeutic drugs	Pregnancy complicated by maternal disorders	Maternal complications of pregnancy	Preg	1968-2006	77	10457	22425	2973196	0.552	0.457	0.663	0.547	29.009	0.542	7.203e-8	-0.0497266	-0.5942072
Infliximab	Compression fracture	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	18	326	22484	2983327	2.707	1.82	3.906	3.357	26.978	3.36	2.058e-7	2.39900712	0.99584101
Infliximab	Computerised tomogram abdomen abnormal	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	1	41	22501	2983612	0.809	0.187	2.524	1.311	0.072	1.311	0.789	0.59475445	-0.2119564
Infliximab	Computerised tomogram abnormal	Imaging procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	29	1177	22473	2982476	1.552	1.136	2.08	1.648	7.062	1.649	0.008	1.56962276	0.43954442
Infliximab	Computerised tomogram thorax abnormal	Respiratory tract and thoracic imaging procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	2	21	22500	2983632	1.682	0.544	4.234	5.84	6.846	5.84	0.009	1.34493959	0.51998356
Infliximab	Concomitant disease progression	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	3	300	22499	2983353	0.558	0.217	1.234	0.574	0.928	0.574	0.335	0.28058623	-0.5833963
Infliximab	Concussion	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	2	365	22500	2983288	0.369	0.12	0.926	0.344	2.434	0.344	0.119	-0.3318307	-0.9969586
Infliximab	Condition aggravated	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	605	67634	21897	2916019	1.19	1.112	1.272	1.197	19.552	1.203	9.792e-6	0.19984741	0.17395331
Infliximab	Conduction disorder	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	2	922	22500	2982731	0.199	0.064	0.499	0.17	8.003	0.17	0.005	-1.4111711	-1.6144505
Infliximab	Condyloma acuminatum				1968-2006	2	71	22500	2983582	1.08	0.35	2.708	1.681	0.52	1.681	0.471	0.94514885	0.07696104
Infliximab	Confusional state	Confusion and disorientation	Deliria (incl confusion)	Psych	1968-2006	155	42600	22347	2941053	0.478	0.418	0.545	0.473	91.795	0.468	9.615e-22	-1.0727672	-0.7381445
Infliximab	Congenital anomaly	Congenital disorders NEC	Congenital and hereditary disorders NEC	Cong	1968-2006	3	11549	22499	2972104	0.153	0.059	0.338	0.136	16.639	0.135	0.00004521	-4.4671546	-1.8773174
Infliximab	Congenital arterial malformation	Arterial disorders congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	166	22501	2983487	1.048	0.242	3.275	2.985	1.296	2.987	0.255	-0.1808744	0.04688359
Infliximab	Congenital bowing of long bones	Musculoskeletal and connective tissue disorders of limbs congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	1	21	22501	2983632	1.053	0.244	3.291	3.24	1.36	3.241	0.244	0.76921993	0.05164323
Infliximab	Congenital hearing disorder	Hearing disorders congenital	Ear and labyrinthine disorders congenital	Cong	1968-2006	1	42	22501	2983611	0.859	0.199	2.683	1.536	0.183	1.536	0.669	0.58656124	-0.1519864
Infliximab	Congenital heart valve disorder	Cardiac valve disorders congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	5	22501	2983648	1.222	0.282	3.832	8.967	5.503	8.967	0.019	0.92577585	0.20048886
Infliximab	Congenital herpes simplex infection	Viral infections congenital	Infections and infestations congenital	Cong	1968-2006	1	2	22501	2983651	1.291	0.297	4.062	23.769	11.416	23.769	0.001	0.95711984	0.25541711
Infliximab	Congenital intestinal malformation	Intestinal disorders congenital	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	34	22501	2983619	0.916	0.212	2.861	1.854	0.382	1.854	0.537	0.65344776	-0.0877389
Infliximab	Congenital megacolon	Intestinal disorders congenital	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	22	22501	2983631	1.073	0.248	3.355	3.32	1.589	3.32	0.207	0.75997701	0.07045846
Infliximab	Congenital teratoma	Congenital disorders NEC	Congenital and hereditary disorders NEC	Cong	1968-2006	2	8	22500	2983645	1.948	0.627	4.956	12.602	17.203	12.602	0.00003358	1.46997828	0.66680321
Infliximab	Congestive cardiomyopathy	Cardiomyopathies	Myocardial disorders	Card	1968-2006	18	815	22484	2982838	1.379	0.927	1.99	1.482	2.698	1.482	0.1	1.38164834	0.3213586
Infliximab	Conjunctival disorder	Conjunctival structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	2	111	22500	2983542	1.054	0.342	2.642	1.58	0.425	1.58	0.515	0.68979161	0.05259245
Infliximab	Conjunctival haemorrhage	Conjunctival and corneal bleeding and vascular disorders	Ocular haemorrhages and vascular disorders NEC	Eye	1968-2006	6	451	22496	2983202	0.774	0.391	1.409	0.819	0.233	0.819	0.63	0.65199455	-0.2561834
Infliximab	Conjunctival hyperaemia	Conjunctival infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	16	466	22486	2983187	1.383	0.908	2.036	1.499	2.55	1.5	0.11	1.87228184	0.32425505
Infliximab	Conjunctival irritation	Conjunctival infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	22	22501	2983631	1.076	0.249	3.363	3.454	1.63	3.454	0.202	0.75997701	0.07325046
Infliximab	Conjunctival oedema	Conjunctival infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	306	22501	2983347	0.393	0.091	1.228	0.362	1.134	0.362	0.287	-0.7325739	-0.9339457
Infliximab	Conjunctivitis	Conjunctival infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	23	11121	22479	2972532	0.912	0.642	1.264	0.931	0.115	0.931	0.735	-1.8307127	-0.0921153
Infliximab	Conjunctivitis allergic	Conjunctival infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	96	22501	2983557	0.571	0.132	1.781	0.644	0.198	0.644	0.656	0.20161885	-0.5603661
Infliximab	Conjunctivitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	14	22501	2983639	1.125	0.26	3.52	4.528	2.414	4.528	0.12	0.83563334	0.11778304
Infliximab	Conjunctivitis viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	1	22	22501	2983631	1.018	0.235	3.179	2.726	1.01	2.726	0.315	0.75997701	0.01783992
Infliximab	Connective tissue disorder	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	5	146	22497	2983507	1.78	0.844	3.401	2.58	4.69	2.58	0.03	1.48300747	0.57661336
Infliximab	Constipation	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	70	27175	22432	2956478	0.274	0.224	0.331	0.268	140.948	0.266	1.652e-32	-1.5533299	-1.2946272
Infliximab	Contusion	Skin injuries NEC	Injuries NEC	Inj&P	1968-2006	50	4188	22452	2979465	0.59	0.465	0.739	0.585	14.53	0.583	0.000138	0.62733822	-0.5276327
Infliximab	Conversion disorder	Somatoform disorders	Somatoform and factitious disorders	Psych	1968-2006	3	827	22499	2982826	0.367	0.142	0.811	0.352	3.596	0.352	0.058	-0.8617994	-1.0023934
Infliximab	Convulsion	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	149	50301	22353	2933352	0.347	0.302	0.396	0.342	192.301	0.337	1e-43	-1.3712088	-1.0584305
Infliximab	Convulsion neonatal	Generalised tonic-clonic seizures	Seizures (incl subtypes)	Nerv	1968-2006	1	361	22501	2983292	0.233	0.054	0.729	0.184	3.647	0.184	0.056	-0.9023089	-1.4567168
Infliximab	Coombs direct test positive	Blood grouping and cross-matching analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	657	22501	2982996	0.409	0.095	1.278	0.379	0.998	0.379	0.318	-1.5780527	-0.8940401
Infliximab	Coombs indirect test positive	Blood grouping and cross-matching analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	70	22501	2983583	1.073	0.248	3.355	3.277	1.593	3.278	0.207	0.37422158	0.07045846
Infliximab	Coombs positive haemolytic anaemia	Anaemias haemolytic immune	Haemolyses and related conditions	Blood	1968-2006	1	849	22501	2982804	0.601	0.139	1.875	0.702	0.125	0.702	0.724	-1.8914474	-0.5091603
Infliximab	Coombs test positive	Blood grouping and cross-matching analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	99	22501	2983554	0.471	0.109	1.471	0.469	0.597	0.469	0.44	0.18296925	-0.7528972
Infliximab	Coordination abnormal	Cerebellar coordination and balance disturbances	Neurological disorders NEC	Nerv	1968-2006	47	13744	22455	2969909	0.652	0.511	0.823	0.65	8.755	0.649	0.003	-1.1361623	-0.4277107
Infliximab	Cor pulmonale	Right ventricular failures	Heart failures	Card	1968-2006	10	325	22492	2983328	2.306	1.354	3.726	3.08	12.764	3.081	0.0003534	1.63795892	0.83551442
Infliximab	Cor pulmonale acute	Right ventricular failures	Heart failures	Card	1968-2006	1	20	22501	2983633	1.059	0.245	3.309	3.275	1.421	3.275	0.233	0.77852244	0.05732507
Infliximab	Corneal abrasion	Eye injuries NEC	Injuries NEC	Inj&P	1968-2006	1	131	22501	2983522	0.528	0.122	1.647	0.557	0.339	0.557	0.561	-0.0022646	-0.638659
Infliximab	Corneal abscess	Eye and eyelid infections	Infections - pathogen class unspecified	Infec	1968-2006	1	17	22501	2983636	1.089	0.252	3.403	3.552	1.803	3.552	0.179	0.80679534	0.08525984
Infliximab	Corneal deposits	Corneal structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	186	22501	2983467	0.406	0.094	1.266	0.372	1.031	0.372	0.31	-0.273815	-0.9014021
Infliximab	Corneal disorder	Corneal disorders NEC	Eye disorders NEC	Eye	1968-2006	2	351	22500	2983302	0.482	0.156	1.209	0.487	1.09	0.487	0.297	-0.2909016	-0.7298112
Infliximab	Corneal dystrophy	Corneal and scleral disorders congenital	Eye disorders congenital	Cong	1968-2006	3	42	22499	2983611	1.942	0.754	4.304	4.715	7.739	4.716	0.005	1.57031335	0.66371837
Infliximab	Corneal erosion	Corneal structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	114	22501	2983539	0.652	0.151	2.036	0.817	0.039	0.817	0.843	0.0931742	-0.4277107
Infliximab	Corneal infection	Eye and eyelid infections	Infections - pathogen class unspecified	Infec	1968-2006	1	16	22501	2983637	1.073	0.248	3.353	3.548	1.593	3.548	0.207	0.81634411	0.07045846
Infliximab	Corneal oedema	Corneal infections, oedemas and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	243	22501	2983410	0.368	0.085	1.149	0.324	1.371	0.324	0.242	-0.5099301	-0.9996723
Infliximab	Corneal perforation	Corneal structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	89	22501	2983564	0.717	0.166	2.239	0.994	0	0.994	0.995	0.24609549	-0.3326794
Infliximab	Corneal reflex decreased	Ophthalmic function diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	95	22501	2983558	0.666	0.154	2.08	0.853	0.024	0.853	0.876	0.20788933	-0.4064656
Infliximab	Corneal transplant	Corneal and scleral therapeutic procedures	Eye therapeutic procedures	Surg	1968-2006	1	100	22501	2983553	0.635	0.147	1.983	0.778	0.062	0.778	0.803	0.1768059	-0.4541303
Infliximab	Coronary angioplasty	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	1	64	22501	2983589	0.663	0.153	2.07	0.844	0.028	0.844	0.868	0.41716601	-0.4109803
Infliximab	Coronary arterial stent insertion	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	8	198	22494	2983455	1.848	1.02	3.138	2.384	5.963	2.384	0.015	1.81303969	0.61410397
Infliximab	Coronary artery aneurysm	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	3	21	22499	2983632	2.502	0.962	5.649	11.997	23.359	12	1.344e-6	1.75079308	0.91709041
Infliximab	Coronary artery bypass	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	1	72	22501	2983581	0.636	0.147	1.984	0.778	0.062	0.777	0.804	0.36018617	-0.4525567
Infliximab	Coronary artery disease	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	149	9019	22353	2974634	1.574	1.373	1.797	1.614	33.297	1.619	7.909e-9	1.0920718	0.45362015
Infliximab	Coronary artery dissection	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	2	55	22500	2983598	1.224	0.397	3.071	2.16	1.217	2.16	0.27	1.06145149	0.20212418
Infliximab	Coronary artery occlusion	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	55	3952	22447	2979701	1.156	0.922	1.434	1.178	1.432	1.179	0.232	0.8407036	0.14496577
Infliximab	Coronary artery restenosis	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	2	235	22500	2983418	0.572	0.185	1.434	0.608	0.504	0.608	0.478	0.10203233	-0.5586163
Infliximab	Coronary artery stenosis	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	39	1528	22463	2982125	1.698	1.298	2.189	1.797	13.093	1.799	0.0002963	1.64024771	0.52945109
Infliximab	Coronary artery surgery				1968-2006	12	875	22490	2982778	1.16	0.713	1.803	1.248	0.575	1.249	0.448	0.75570494	0.14842001
Infliximab	Coronary artery thrombosis	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	11	600	22491	2983053	1.014	0.61	1.605	1.077	0.059	1.077	0.808	1.09524308	0.01390291
Infliximab	Coronary ostial stenosis	Coronary artery disorders NEC	Coronary artery disorders	Card	1968-2006	3	39	22499	2983614	2.027	0.786	4.496	5.319	9.203	5.32	0.002	1.59475468	0.70655687
Infliximab	Corynebacterium infection	Corynebacteria infections	Bacterial infectious disorders	Infec	1968-2006	4	86	22498	2983567	1.703	0.743	3.461	2.658	4.039	2.658	0.044	1.56802418	0.5323914
Infliximab	Costochondritis	Cartilage disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	2	202	22500	2983451	0.673	0.218	1.686	0.76	0.149	0.76	0.7	0.23659806	-0.3960099
Infliximab	Cough	Coughing and associated symptoms	Respiratory disorders NEC	Resp	1968-2006	343	29156	22159	2954497	1.448	1.324	1.581	1.469	50.164	1.477	1.414e-12	0.60808361	0.37018329
Infliximab	Cows milk intolerance	Food malabsorption and intolerance syndromes (excl sugar intolerance)	Food intolerance syndromes	Metab	1968-2006	1	32	22501	2983621	0.965	0.223	3.014	2.228	0.631	2.228	0.427	0.67066536	-0.0356272
Infliximab	Coxiella infection	Coxiella infections	Rickettsial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.375	0.313	4.373	116.878	49.405	116.878	2.082e-12	0.967721	0.31845373
Infliximab	Coxsackie viral infection	Coxsackie viral infections	Viral infectious disorders	Infec	1968-2006	1	40	22501	2983613	0.959	0.222	2.996	2.118	0.593	2.118	0.441	0.60299444	-0.0418642
Infliximab	Cranial nerve disorder	Cranial nerve disorders NEC	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	3	111	22499	2983542	1.303	0.506	2.881	1.955	1.301	1.955	0.254	1.09899023	0.2646693
Infliximab	Cranial neuropathy	Cranial nerve disorders NEC	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	25	22501	2983628	0.953	0.221	2.977	2.128	0.562	2.128	0.454	0.7325983	-0.0481404
Infliximab	Creatine phosphokinase decreased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	3	140	22499	2983513	1.019	0.396	2.253	1.298	0.198	1.298	0.657	0.93918351	0.01882175
Infliximab	Creatinine renal clearance increased	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	72	22501	2983581	0.574	0.133	1.792	0.646	0.19	0.646	0.663	0.36018617	-0.5551259
Infliximab	Crepitations	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	19	925	22483	2982728	1.573	1.069	2.249	1.709	5.398	1.71	0.02	1.29876419	0.45298462
Infliximab	Creutzfeldt-Jakob disease	Prion-associated disorders	Viral infectious disorders	Infec	1968-2006	2	25	22500	2983628	1.615	0.523	4.061	4.595	5.486	4.595	0.019	1.30854889	0.47933496
Infliximab	Crohns disease	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	374	876	22128	2982777	16.618	15.25	18.08	26.578	5655.055	27.05	0	5.16698379	2.81048645
Infliximab	Croup infectious	Parainfluenzae viral infections	Viral infectious disorders	Infec	1968-2006	1	100	22501	2983553	0.692	0.16	2.16	0.923	0.006	0.923	0.936	0.1768059	-0.3681693
Infliximab	Crying	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	11	4183	22491	2979470	0.156	0.094	0.248	0.149	53.534	0.148	2.541e-13	-1.4455274	-1.8578993
Infliximab	Cryoglobulinaemia	Autoimmune disorders NEC	Autoimmune disorders	Immun	1968-2006	5	92	22497	2983561	2.104	0.997	4.023	3.55	8.282	3.551	0.004	1.78658217	0.74384029
Infliximab	Cryoglobulins present	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	3	17	22499	2983636	2.386	0.921	5.347	9.855	18.812	9.86	0.00001443	1.78788545	0.86961832
Infliximab	Cryptococcosis	Cryptococcal infections	Fungal infectious disorders	Infec	1968-2006	19	152	22483	2983501	5.824	3.892	8.676	9.604	121.833	9.61	2.511e-28	3.1219854	1.76198731
Infliximab	Cryptogenic organising pneumonia	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	3	47	22499	2983606	2.036	0.79	4.517	5.704	9.34	5.704	0.002	1.53047593	0.7109871
Infliximab	Cryptogenic organizing pneumonia				1968-2006	32	459	22470	2983194	3.627	2.695	4.799	4.357	75.985	4.362	2.859e-18	2.80827539	1.28840586
Infliximab	Crystal arthropathy	Crystal arthropathic disorders	Joint disorders	Musc	1968-2006	1	8	22501	2983645	1.156	0.267	3.619	5.412	3.111	5.412	0.078	0.89509832	0.14496577
Infliximab	Crystal urine present	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	128	22501	2983525	0.648	0.15	2.024	0.808	0.044	0.808	0.834	0.01412534	-0.4338646
Infliximab	Cubital tunnel syndrome	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	1	19	22501	2983634	1.125	0.26	3.517	4.653	2.382	4.653	0.123	0.78788532	0.11778304
Infliximab	Culture negative	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	1	1	22501	2983652	1.368	0.312	4.344	1085.627	76.697	1093.411	1.993e-18	0.967721	0.31334982
Infliximab	Culture positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	16	301	22486	2983352	2.899	1.903	4.271	3.684	29.1	3.686	6.874e-8	2.32251107	1.06436585
Infliximab	Culture stool positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	5	195	22497	2983458	1.266	0.6	2.418	1.57	0.983	1.571	0.321	1.25379673	0.23586232
Infliximab	Culture throat positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	1	35	22501	2983618	1.031	0.238	3.22	2.817	1.117	2.817	0.291	0.64491541	0.03052921
Infliximab	Culture urine positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	26	628	22476	2983025	2.181	1.568	2.969	2.451	20.8	2.453	5.098e-6	2.18415537	0.77978349
Infliximab	Culture wound positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	1	114	22501	2983539	0.522	0.121	1.631	0.55	0.359	0.55	0.549	0.0931742	-0.6500877
Infliximab	Cushings syndrome	Adrenal cortical hyperfunctions	Adrenal gland disorders	Endo	1968-2006	8	738	22494	2982915	1.364	0.753	2.315	1.587	1.656	1.587	0.198	0.43975578	0.31042156
Infliximab	Cushingoid	Adrenal cortical hyperfunctions	Adrenal gland disorders	Endo	1968-2006	16	365	22486	2983288	2.75	1.805	4.051	3.469	25.79	3.471	3.806e-7	2.13087435	1.01160091
Infliximab	Cutaneous leishmaniasis	Leishmania infections	Protozoal infectious disorders	Infec	1968-2006	4	5	22498	2983648	10.198	2.021	52.56	86.46	163.296	86.631	2.155e-37	2.21702652	2.32219162
Infliximab	Cutaneous lupus erythematosus	Connective tissue disorders	Epidermal and dermal conditions	Skin	1968-2006	39	252	22463	2983401	5.852	4.456	7.606	8.087	200.03	8.099	2.057e-45	3.64274029	1.76678348
Infliximab	Cutaneous tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	7	12	22495	2983641	7.547	2.932	23.188	31.036	113.45	31.055	1.72e-26	2.79730973	2.02115013
Infliximab	Cutaneous vasculitis	Skin vasculitides	Skin vascular abnormalities	Skin	1968-2006	16	306	22486	2983347	2.844	1.867	4.19	3.625	27.898	3.627	1.279e-7	2.30658808	1.04521151
Infliximab	Cyanopsia	Visual colour distortions	Vision disorders	Eye	1968-2006	1	131	22501	2983522	0.494	0.114	1.541	0.507	0.482	0.507	0.488	-0.0022646	-0.7052198
Infliximab	Cyanosis	Cardiac signs and symptoms NEC	Cardiac disorder signs and symptoms	Card	1968-2006	163	8252	22339	2975401	2.493	2.189	2.83	2.615	154.639	2.629	1.679e-35	1.34296766	0.9134868
Infliximab	Cyanosis central	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	1	38	22501	2983615	0.822	0.19	2.565	1.365	0.095	1.365	0.758	0.61961696	-0.1960149
Infliximab	Cyst	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	20	3363	22482	2980290	1.179	0.809	1.672	1.237	0.876	1.237	0.349	-0.3383894	0.16466662
Infliximab	Cyst drainage	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	10	22501	2983643	1.158	0.268	3.624	5.354	3.149	5.354	0.076	0.87500312	0.14669438
Infliximab	Cyst removal	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	3	35	22499	2983618	2	0.776	4.436	4.896	8.747	4.896	0.003	1.6280008	0.69314718
Infliximab	Cyst rupture	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	4	33	22498	2983620	2.393	1.043	4.883	5.772	13.635	5.773	0.0002219	1.95836163	0.87254781
Infliximab	Cystitis	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	33	3320	22469	2980333	1.015	0.758	1.337	1.036	0.04	1.036	0.841	0.36913702	0.01488861
Infliximab	Cystitis haemorrhagic	Bladder infections and inflammations	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	8	787	22494	2982866	0.954	0.526	1.619	1.026	0.005	1.026	0.942	0.36152202	-0.0470916
Infliximab	Cystitis klebsiella	Klebsiella infections	Bacterial infectious disorders	Infec	1968-2006	1	22	22501	2983631	1.102	0.255	3.444	3.985	1.995	3.985	0.158	0.75997701	0.09712671
Infliximab	Cystitis noninfective	Bladder infections and inflammations	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	3	59	22499	2983594	1.665	0.647	3.683	3.142	4.106	3.142	0.043	1.43912756	0.50982512
Infliximab	Cystocele	Pelvic prolapse conditions	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	2	101	22500	2983552	0.915	0.297	2.294	1.236	0.085	1.236	0.771	0.74952034	-0.0888312
Infliximab	Cystoscopy	Urinary tract imaging procedures	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	5	22501	2983648	1.294	0.298	4.071	15.541	11.637	15.541	0.001	0.92577585	0.2577382
Infliximab	Cytolytic hepatitis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	16	1182	22486	2982471	0.744	0.488	1.095	0.755	1.25	0.755	0.264	0.75883474	-0.2957142
Infliximab	Cytomegalovirus antibody positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	12	143	22490	2983510	3.055	1.878	4.756	4.344	27.846	4.347	1.313e-7	2.57834862	1.11677959
Infliximab	Cytomegalovirus antigen positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	5	143	22497	2983510	1.463	0.694	2.795	1.931	2.131	1.932	0.144	1.49829749	0.38048912
Infliximab	Cytomegalovirus chorioretinitis	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	2	181	22500	2983472	0.642	0.208	1.609	0.712	0.232	0.712	0.63	0.3292632	-0.443167
Infliximab	Cytomegalovirus colitis	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	8	60	22494	2983593	3.583	1.969	6.143	7.046	36.071	7.047	1.903e-9	2.56546019	1.27620044
Infliximab	Cytomegalovirus enteritis	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	1	12	22501	2983641	1.126	0.26	3.522	4.69	2.425	4.69	0.119	0.85518395	0.11867153
Infliximab	Cytomegalovirus enterocolitis	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	3	28	22499	2983625	2.204	0.854	4.906	6.977	13.139	6.979	0.0002893	1.68809108	0.79027389
Infliximab	Cytomegalovirus gastritis	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	2	11	22500	2983642	1.798	0.581	4.537	8.151	10.113	8.152	0.001	1.4401465	0.58667494
Infliximab	Cytomegalovirus gastrointestinal infection	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	2	7	22500	2983646	2.091	0.665	5.412	19.684	29.142	19.684	6.726e-8	1.48006086	0.73764242
Infliximab	Cytomegalovirus hepatitis	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	3	55	22499	2983598	1.912	0.742	4.237	4.347	7.231	4.347	0.007	1.46893902	0.64814981
Infliximab	Cytomegalovirus infection	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	101	1603	22401	2982050	4.033	3.416	4.735	4.527	251.901	4.543	0	2.8789274	1.39451052
Infliximab	Cytomegalovirus syndrome	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	1	9	22501	2983644	1.121	0.259	3.506	4.567	2.337	4.567	0.126	0.88501574	0.11422114
Infliximab	Cytomegalovirus test positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	4	67	22498	2983586	1.861	0.812	3.783	3.188	5.619	3.189	0.018	1.69615018	0.62111398
Infliximab	Cytomegalovirus viraemia	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	1	76	22501	2983577	0.658	0.152	2.055	0.836	0.032	0.836	0.857	0.33251843	-0.4185503
Infliximab	DNA antibody	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	3	18	22499	2983635	2.575	0.986	5.858	16.662	27.133	16.665	0.00000019	1.77852258	0.94584953
Infliximab	DNA antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	92	156	22410	2983497	21.7	18.218	25.689	45.251	1892.88	45.505	0	5.0140529	3.07731226
Infliximab	Dacryostenosis acquired	Lid, lash and lacrimal structural disorders	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	131	22501	2983522	0.452	0.104	1.411	0.437	0.706	0.437	0.401	-0.0022646	-0.7940731
Infliximab	Dandruff	Scalar conditions	Epidermal and dermal conditions	Skin	1968-2006	1	20	22501	2983633	1.095	0.253	3.423	3.676	1.885	3.677	0.17	0.77852244	0.09075436
Infliximab	Dark circles under eyes	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	1	20	22501	2983633	1.032	0.239	3.223	2.905	1.137	2.905	0.286	0.77852244	0.03149867
Infliximab	Deafness	Hearing losses	Hearing disorders	Ear	1968-2006	36	6554	22466	2977099	0.956	0.723	1.245	0.97	0.032	0.97	0.858	-0.4578525	-0.0449974
Infliximab	Deafness bilateral	Hearing losses	Hearing disorders	Ear	1968-2006	1	125	22501	2983528	0.433	0.1	1.351	0.412	0.83	0.412	0.362	0.03070362	-0.8370176
Infliximab	Deafness neurosensory	Hearing losses	Hearing disorders	Ear	1968-2006	8	501	22494	2983152	1.033	0.57	1.754	1.127	0.113	1.127	0.737	0.89279972	0.03246719
Infliximab	Deafness unilateral	Hearing losses	Hearing disorders	Ear	1968-2006	9	436	22493	2983217	0.98	0.559	1.619	1.05	0.02	1.05	0.886	1.1961899	-0.0202027
Infliximab	Death	Death and sudden death	Fatal outcomes	Genrl	1968-2006	344	36974	22158	2946679	0.763	0.697	0.833	0.759	26.551	0.754	2.566e-7	0.27060674	-0.2704972
Infliximab	Death neonatal	Death and sudden death	Fatal outcomes	Genrl	1968-2006	8	287	22494	2983366	1.55	0.856	2.631	1.858	3.073	1.859	0.08	1.47719733	0.43825493
Infliximab	Decerebration	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	1	50	22501	2983603	0.727	0.168	2.268	1.021	0	1.021	0.983	0.52263848	-0.3188288
Infliximab	Decreased activity	Decreased physical activity levels	Changes in physical activity	Psych	1968-2006	15	2304	22487	2981349	0.6	0.388	0.893	0.602	3.923	0.601	0.048	-0.2103241	-0.5108256
Infliximab	Decreased appetite	Appetite disorders	Appetite and general nutritional disorders	Metab	1968-2006	61	9571	22441	2974082	0.505	0.408	0.62	0.501	30.244	0.499	3.809e-8	-0.2530475	-0.6831968
Infliximab	Decubitus ulcer	Skin injuries and mechanical dermatoses	Epidermal and dermal conditions	Skin	1968-2006	18	836	22484	2982817	1.311	0.882	1.891	1.397	1.971	1.398	0.16	1.35063022	0.2707902
Infliximab	Deep vein thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	153	9700	22349	2973953	1.131	0.989	1.289	1.14	2.598	1.141	0.107	1.02719464	0.1231022
Infliximab	Defaecation urgency	Gastrointestinal spastic and hypermotility disorders	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	3	398	22499	2983255	0.573	0.223	1.266	0.594	0.821	0.594	0.365	-0.0116117	-0.5568696
Infliximab	Deformity	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	100	22501	2983553	0.466	0.108	1.454	0.463	0.629	0.463	0.428	0.1768059	-0.7635696
Infliximab	Dehydration	Total fluid volume decreased	Electrolyte and fluid balance conditions	Metab	1968-2006	202	20496	22300	2963157	0.77	0.685	0.863	0.767	14.243	0.765	0.0001607	0.35978908	-0.2613648
Infliximab	Delayed puberty	Endocrine abnormalities of puberty	Endocrine disorders of gonadal function	Endo	1968-2006	1	27	22501	2983626	1.061	0.245	3.316	3.17	1.44	3.17	0.23	0.71463025	0.05921186
Infliximab	Delayed recovery from anaesthesia	Anaesthetic complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	245	22501	2983408	0.322	0.074	1.005	0.271	1.917	0.271	0.166	-0.5175524	-1.1332037
Infliximab	Delirium	Deliria	Deliria (incl confusion)	Psych	1968-2006	24	7212	22478	2976441	0.448	0.318	0.617	0.442	16.779	0.441	0.00004199	-1.156121	-0.802962
Infliximab	Delusion	Delusional symptoms	Disturbances in thinking and perception	Psych	1968-2006	4	3242	22498	2980411	0.138	0.06	0.281	0.126	24.516	0.125	7.371e-7	-2.351391	-1.9805016
Infliximab	Delusional disorder, persecutory type	Delusional disorders	Schizophrenia and other psychotic disorders	Psych	1968-2006	2	193	22500	2983460	0.66	0.214	1.654	0.742	0.182	0.742	0.67	0.27558539	-0.4155154
Infliximab	Dementia	Dementia (excl Alzheimers type)	Mental impairment disorders	Nerv	1968-2006	12	3340	22490	2980313	0.476	0.293	0.741	0.471	7.028	0.471	0.008	-1.0174816	-0.7423374
Infliximab	Dementia Alzheimers type	Alzheimers disease (incl subtypes)	Mental impairment disorders	Nerv	1968-2006	4	607	22498	2983046	0.447	0.195	0.908	0.442	2.818	0.442	0.093	-0.1677941	-0.8051967
Infliximab	Demyelinating polyneuropathy	Chronic polyneuropathies	Peripheral neuropathies	Nerv	1968-2006	18	154	22484	2983499	5.174	3.452	7.602	8.492	97.409	8.501	5.638e-23	3.0432554	1.64364608
Infliximab	Demyelination	Demyelinating disorders NEC	Demyelinating disorders	Nerv	1968-2006	66	642	22436	2983011	5.119	4.165	6.242	6.183	252.289	6.2	0	3.39967521	1.63295911
Infliximab	Dental caries	Dental and periodontal infections and inflammations	Dental and gingival conditions	Gastr	1968-2006	8	1090	22494	2982563	0.757	0.418	1.285	0.787	0.454	0.787	0.5	-0.0460308	-0.278392
Infliximab	Dental treatment	Dental and gingival therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	1	165	22501	2983488	0.404	0.093	1.26	0.369	1.048	0.369	0.306	-0.1760665	-0.9063404
Infliximab	Dependence	Substance-related disorders	Psychiatric disorders NEC	Psych	1968-2006	1	2313	22501	2981340	0.031	0.007	0.098	0.021	46.372	0.021	9.782e-12	-3.207384	-3.4737681
Infliximab	Dependence on enabling machine or device	Disability issues	Lifestyle issues	SocCi	1968-2006	1	13	22501	2983640	1.201	0.277	3.764	6.698	4.507	6.698	0.034	0.84537553	0.18315454
Infliximab	Dependence on respirator	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	1	18	22501	2983635	1.005	0.232	3.138	2.508	0.908	2.508	0.341	0.79730935	0.00498754
Infliximab	Depersonalisation	Dissociative states	Dissociative disorders	Psych	1968-2006	2	3618	22500	2980035	0.245	0.079	0.615	0.214	5.655	0.214	0.017	-3.2399612	-1.4064971
Infliximab	Depressed level of consciousness	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	76	11030	22426	2972623	0.502	0.414	0.603	0.496	38.696	0.494	4.952e-10	-0.1439754	-0.6891552
Infliximab	Depressed mood	Mood alterations with depressive symptoms	Depressed mood disorders and disturbances	Psych	1968-2006	2	1673	22500	2981980	0.084	0.027	0.21	0.067	25.514	0.067	4.392e-7	-2.1856164	-2.4769385
Infliximab	Depression	Depressive disorders	Depressed mood disorders and disturbances	Psych	1968-2006	144	45323	22358	2938330	0.347	0.302	0.397	0.341	185.594	0.337	2.912e-42	-1.2680553	-1.0584305
Infliximab	Dermal cyst	Skin neoplasms benign	Cutaneous neoplasms benign	Skin	1968-2006	5	161	22497	2983492	1.461	0.693	2.79	1.916	2.114	1.916	0.146	1.40889709	0.37912113
Infliximab	Dermatitis	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	160	117254	22342	2866399	1.36	1.192	1.546	1.374	16.537	1.39	0.0000477	-2.5189248	0.3074847
Infliximab	Dermatitis acneiform	Acnes	Skin appendage conditions	Skin	1968-2006	1	326	22501	2983327	0.242	0.056	0.757	0.19	3.402	0.19	0.065	-0.7966292	-1.4188176
Infliximab	Dermatitis allergic	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	3	489	22499	2983164	0.344	0.134	0.761	0.326	4.151	0.326	0.042	-0.2384382	-1.0671136
Infliximab	Dermatitis atopic	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	5	324	22497	2983329	1.019	0.483	1.946	1.17	0.12	1.17	0.729	0.78208284	0.01882175
Infliximab	Dermatitis bullous	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	14	9828	22488	2973825	0.588	0.375	0.888	0.591	3.952	0.591	0.047	-2.3311725	-0.5310283
Infliximab	Dermatitis contact	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	2	5492	22500	2978161	0.208	0.067	0.521	0.178	7.482	0.178	0.006	-3.8251142	-1.5702172
Infliximab	Dermatitis exfoliative	Exfoliative conditions	Epidermal and dermal conditions	Skin	1968-2006	25	12762	22477	2970891	0.572	0.409	0.783	0.57	8.028	0.57	0.005	-1.9122452	-0.5586163
Infliximab	Dermatitis exfoliative generalised	Exfoliative conditions	Epidermal and dermal conditions	Skin	1968-2006	2	36	22500	2983617	1.54	0.499	3.868	4.283	4.268	4.283	0.039	1.2129632	0.43178242
Infliximab	Dermatitis herpetiformis	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	1	37	22501	2983616	0.929	0.215	2.9	1.941	0.435	1.942	0.51	0.62800058	-0.0736465
Infliximab	Dermatitis psoriasiform	Psoriatic conditions	Epidermal and dermal conditions	Skin	1968-2006	20	128	22482	2983525	6.426	4.281	9.807	11.256	144.506	11.264	2.754e-33	3.30565625	1.86035226
Infliximab	Dermatofibrosarcoma	Fibrosarcomas malignant	Soft tissue sarcomas	Neopl	1968-2006	1	4	22501	2983649	1.287	0.296	4.047	19.492	10.721	19.492	0.001	0.93614837	0.25231393
Infliximab	Dermatomyositis	Connective tissue disorders	Epidermal and dermal conditions	Skin	1968-2006	6	413	22496	2983240	1.163	0.587	2.117	1.353	0.527	1.354	0.468	0.74795948	0.15100287
Infliximab	Dermatosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	4	32	22498	2983621	2.457	1.07	5.019	6.057	14.941	6.058	0.0001109	1.96684382	0.89894109
Infliximab	Dermographism	Urticarias	Angioedema and urticaria	Skin	1968-2006	1	49	22501	2983604	0.899	0.208	2.806	1.729	0.31	1.729	0.578	0.53047566	-0.1064722
Infliximab	Dermoid cyst	Skin and subcutaneous tissue disorders congenital NEC	Skin and subcutaneous tissue disorders congenital	Cong	1968-2006	2	37	22500	2983616	1.419	0.46	3.562	3.178	2.772	3.178	0.096	1.20457957	0.3499524
Infliximab	Developmental delay	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	625	22500	2983028	0.209	0.068	0.525	0.181	7.415	0.181	0.006	-0.9354408	-1.565421
Infliximab	Device failure	Device component findings	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	4	1403	22498	2982250	0.177	0.077	0.359	0.161	17.439	0.161	0.00002967	-1.2171386	-1.7316055
Infliximab	Device interaction	Device related complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	36	22501	2983617	0.973	0.225	3.04	2.273	0.678	2.273	0.41	0.63643321	-0.0273712
Infliximab	Device malfunction	Device malfunction events	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	191	22501	2983462	0.35	0.081	1.094	0.303	1.563	0.303	0.211	-0.296144	-1.0498221
Infliximab	Device migration	Device related complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	5107	22501	2978546	0.365	0.084	1.141	0.323	1.393	0.323	0.238	-4.3073776	-1.0078579
Infliximab	Device occlusion	Device malfunction events	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	33	22500	2983620	1.31	0.424	3.286	2.592	1.808	2.593	0.179	1.23841037	0.27002714
Infliximab	Device related infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	52	738	22450	2982915	4.373	3.466	5.46	5.222	158.564	5.234	2.331e-36	2.92732727	1.47544927
Infliximab	Dextrocardia	Cardiac malpositions congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	33	22501	2983620	0.94	0.217	2.935	2.016	0.491	2.016	0.483	0.66203088	-0.0618754
Infliximab	Diabetes insipidus	Posterior pituitary disorders	Hypothalamus and pituitary gland disorders	Endo	1968-2006	1	710	22501	2982943	0.24	0.055	0.75	0.19	3.462	0.19	0.063	-1.6715755	-1.4271164
Infliximab	Diabetes mellitus	Diabetes mellitus (incl subtypes)	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	89	11577	22413	2972076	0.634	0.531	0.752	0.629	19.226	0.628	0.00001161	0.01067829	-0.4557063
Infliximab	Diabetes mellitus inadequate control	Diabetes mellitus (incl subtypes)	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	7	3625	22495	2980028	0.132	0.07	0.231	0.122	43.891	0.122	3.471e-11	-1.829532	-2.0249534
Infliximab	Diabetes mellitus insulin-dependent	Diabetes mellitus (incl subtypes)	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	3	647	22499	2983006	0.303	0.118	0.671	0.283	5.42	0.283	0.02	-0.5633937	-1.1940225
Infliximab	Diabetes mellitus non-insulin-dependent	Diabetes mellitus (incl subtypes)	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	14	1590	22488	2982063	0.589	0.376	0.89	0.59	3.919	0.589	0.048	0.19412892	-0.5293291
Infliximab	Diabetic coma	Coma states	Neurological disorders NEC	Nerv	1968-2006	2	682	22500	2982971	0.292	0.095	0.732	0.261	4.106	0.261	0.043	-1.0397262	-1.2310015
Infliximab	Diabetic complication	Diabetic complications NEC	Diabetic complications	Metab	1968-2006	2	281	22500	2983372	0.49	0.159	1.227	0.491	1.03	0.491	0.31	-0.0667919	-0.7133499
Infliximab	Diabetic foot	Diabetic complications dermal	Diabetic complications	Metab	1968-2006	1	100	22501	2983553	0.68	0.157	2.123	0.89	0.013	0.89	0.908	0.1768059	-0.3856625
Infliximab	Diabetic ketoacidosis	Diabetic complications NEC	Diabetic complications	Metab	1968-2006	4	1841	22498	2981812	0.184	0.08	0.373	0.166	16.442	0.166	0.00005015	-1.5783391	-1.6928195
Infliximab	Diabetic neuropathy	Chronic polyneuropathies	Peripheral neuropathies	Nerv	1968-2006	2	506	22500	2983147	0.294	0.095	0.738	0.266	4.031	0.266	0.045	-0.6899177	-1.2241755
Infliximab	Diabetic retinopathy	Retinopathies NEC	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	511	22501	2983142	0.158	0.036	0.493	0.116	6.755	0.116	0.009	-1.2838491	-1.8451602
Infliximab	Diabetic ulcer	Skin and subcutaneous tissue ulcerations	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	3	46	22499	2983607	1.724	0.67	3.816	3.475	4.75	3.476	0.029	1.53835591	0.54464717
Infliximab	Dialysis	Haematological therapeutic procedures NEC	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	39	4571	22463	2979082	0.535	0.409	0.69	0.531	16.083	0.53	0.00006062	0.15883463	-0.6254885
Infliximab	Diaphragmatic disorder	Diaphragmatic disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	2	134	22500	2983519	0.855	0.277	2.143	1.1	0.017	1.1	0.896	0.56113044	-0.1566538
Infliximab	Diaphragmatic hernia	Diaphragmatic disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	1	65	22501	2983588	0.761	0.176	2.375	1.135	0.015	1.135	0.902	0.40991926	-0.2731219
Infliximab	Diaphragmatic paralysis	Diaphragmatic disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	1	99	22501	2983554	0.557	0.129	1.739	0.611	0.238	0.611	0.626	0.18296925	-0.58519
Infliximab	Diaphragmatic rupture	Diaphragmatic disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	1	5	22501	2983648	1.269	0.292	3.986	16.497	8.726	16.497	0.003	0.92577585	0.23822919
Infliximab	Diarrhoea	Diarrhoea (excl infective)	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	510	73778	21992	2909875	0.819	0.761	0.88	0.816	21.45	0.811	3.632e-6	-0.171493	-0.1996712
Infliximab	Diarrhoea haemorrhagic	Diarrhoea (excl infective)	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	25	2241	22477	2981412	1.303	0.931	1.784	1.366	2.373	1.367	0.123	0.52166388	0.2646693
Infliximab	Diarrhoea infectious	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	65	22500	2983588	1.195	0.387	2.996	2.093	1.047	2.093	0.306	0.98767138	0.17814619
Infliximab	Diastolic dysfunction	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	9	349	22493	2983304	1.454	0.83	2.404	1.695	2.413	1.695	0.12	1.43131533	0.37431838
Infliximab	Diastolic hypertension	Vascular hypertensive disorders NEC	Vascular hypertensive disorders	Vasc	1968-2006	2	18	22500	2983635	1.69	0.547	4.255	6.114	7.052	6.115	0.008	1.37284789	0.52472853
Infliximab	Differential white blood cell count abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	191	22499	2983462	1.176	0.457	2.6	1.626	0.692	1.626	0.405	0.69502085	0.16211885
Infliximab	Difficult to wean from ventilator	Respiratory tract and thoracic cavity procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	49	22501	2983604	0.809	0.187	2.524	1.317	0.072	1.317	0.789	0.53047566	-0.2119564
Infliximab	Difficulty in walking				1968-2006	116	9418	22386	2974235	0.789	0.676	0.917	0.788	6.58	0.786	0.01	0.67774565	-0.236989
Infliximab	Diffuse alveolar damage	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	5	132	22497	2983521	1.816	0.861	3.47	2.702	5.03	2.703	0.025	1.55578926	0.59663628
Infliximab	Diffuse large B-cell lymphoma	Diffuse large B-cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	52	188	22450	2983465	11.924	9.072	15.211	17.842	563.637	17.885	0	4.23337271	2.47855318
Infliximab	Diffuse large B-cell lymphoma stage I	Diffuse large B-cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	3	22501	2983650	1.256	0.29	3.943	13.927	7.637	13.927	0.006	0.946596	0.22793207
Infliximab	Diffuse large B-cell lymphoma stage II	Diffuse large B-cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	3	1	22499	2983652	4.006	1.211	30.089	308.302	105.347	308.302	1.025e-24	1.94659604	1.38779324
Infliximab	Diffuse large B-cell lymphoma stage III	Diffuse large B-cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	4	8	22498	2983645	4.258	1.58	19.471	36.814	77.954	36.814	1.055e-18	2.18698773	1.44879957
Infliximab	Diffuse large B-cell lymphoma stage IV	Diffuse large B-cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	4	13	22498	2983640	3.394	1.42	7.772	15.62	47.393	15.621	5.808e-12	2.13827238	1.22200917
Infliximab	Diffuse panbronchiolitis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	1	2	22501	2983651	1.33	0.305	4.202	52.754	19.726	52.754	8.939e-6	0.95711984	0.28517894
Infliximab	Dilatation atrial	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	18	779	22484	2982874	1.346	0.905	1.941	1.444	2.332	1.444	0.127	1.43642379	0.29713723
Infliximab	Dilatation ventricular	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	16	710	22486	2982943	1.194	0.784	1.759	1.269	0.876	1.269	0.349	1.39048886	0.17730901
Infliximab	Diphtheria	Corynebacteria infections	Bacterial infectious disorders	Infec	1968-2006	1	19	22501	2983634	1.031	0.238	3.219	2.862	1.124	2.862	0.289	0.78788532	0.03052921
Infliximab	Diplegia	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	4	220	22498	2983433	0.85	0.371	1.728	0.955	0.008	0.955	0.927	0.89052163	-0.1625189
Infliximab	Diplopia	Visual disorders NEC	Vision disorders	Eye	1968-2006	42	5614	22460	2978039	0.896	0.692	1.146	0.905	0.408	0.905	0.523	-0.0248154	-0.1098149
Infliximab	Disability	Disability issues	Lifestyle issues	SocCi	1968-2006	1	547	22501	2983106	0.155	0.036	0.485	0.114	6.933	0.114	0.008	-1.3621518	-1.8643302
Infliximab	Discomfort	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	14	1820	22488	2981833	0.54	0.344	0.815	0.538	5.473	0.537	0.019	0.01467629	-0.6161861
Infliximab	Disease progression	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	68	6611	22434	2977042	0.565	0.461	0.686	0.56	23.35	0.558	1.351e-6	0.42221903	-0.5709295
Infliximab	Disease recurrence	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	100	2804	22402	2980849	1.741	1.474	2.046	1.804	34.23	1.809	4.897e-9	2.13902317	0.55445966
Infliximab	Dislocation of joint prosthesis	Device malfunction events	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	4	38	22498	2983615	2.174	0.948	4.426	4.511	9.774	4.512	0.002	1.9166829	0.77656879
Infliximab	Dislocation of vertebra	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	5	51	22497	2983602	2.761	1.306	5.305	6.173	19.321	6.173	0.00001105	2.06904175	1.01559293
Infliximab	Disorientation	Confusion and disorientation	Deliria (incl confusion)	Psych	1968-2006	47	7273	22455	2976380	0.447	0.35	0.564	0.441	33.027	0.44	9.091e-9	-0.2313955	-0.8051967
Infliximab	Disseminated cryptococcosis	Cryptococcal infections	Fungal infectious disorders	Infec	1968-2006	5	13	22497	2983640	4.683	1.934	16.828	25.622	76.264	25.624	2.482e-18	2.39175808	1.54393893
Infliximab	Disseminated cytomegaloviral infection	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	3	21	22499	2983632	2.238	0.867	4.986	7.391	14.097	7.392	0.0001737	1.75079308	0.80558261
Infliximab	Disseminated intravascular coagulation	Coagulopathies	Coagulopathies and bleeding diatheses (excl thrombocytopenic)	Blood	1968-2006	85	4893	22417	2978760	1.361	1.135	1.62	1.389	9.021	1.391	0.003	1.15522211	0.30821972
Infliximab	Disseminated tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	222	157	22280	2983496	31.568	28.23	35.21	90.065	6793.157	91.079	0	5.85000425	3.45214395
Infliximab	Dissociative disorder	Dissociative states	Dissociative disorders	Psych	1968-2006	2	77	22500	2983576	0.98	0.318	2.458	1.395	0.214	1.395	0.644	0.90384367	-0.0202027
Infliximab	Distal ileal obstruction syndrome	Duodenal and small intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	1	2	22501	2983651	1.278	0.295	4.018	16.655	9.795	16.655	0.002	0.95711984	0.24529636
Infliximab	Disturbance in attention	Mental impairment (excl dementia and memory loss)	Mental impairment disorders	Nerv	1968-2006	16	6012	22486	2977641	0.162	0.106	0.239	0.156	73.389	0.155	1.064e-17	-1.4536513	-1.8201589
Infliximab	Diverticular fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	1	5	22501	2983648	1.263	0.291	3.968	13.609	8.202	13.609	0.004	0.92577585	0.23348984
Infliximab	Diverticular perforation	Gastrointestinal ulcers and perforation, site unspecified	Gastrointestinal ulceration and perforation	Gastr	1968-2006	24	265	22478	2983388	4.173	2.958	5.759	5.667	79.352	5.672	5.197e-19	2.97147603	1.4286352
Infliximab	Diverticulitis	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	97	1856	22405	2981797	2.927	2.471	3.447	3.189	134.003	3.2	5.456e-31	2.63775829	1.07397801
Infliximab	Diverticulitis intestinal haemorrhagic	Diverticulum inflammations	Diverticular disorders	Gastr	1968-2006	1	60	22501	2983593	0.761	0.176	2.374	1.129	0.015	1.129	0.903	0.44652257	-0.2731219
Infliximab	Diverticulum	Diverticula	Diverticular disorders	Gastr	1968-2006	34	1230	22468	2982423	1.764	1.323	2.314	1.887	13.434	1.889	0.0002472	1.73083992	0.56758396
Infliximab	Diverticulum intestinal	Diverticula	Diverticular disorders	Gastr	1968-2006	15	463	22487	2983190	1.895	1.227	2.824	2.184	9.107	2.185	0.003	1.79422545	0.63921884
Infliximab	Diverticulum intestinal haemorrhagic	Diverticula	Diverticular disorders	Gastr	1968-2006	4	126	22498	2983527	1.481	0.647	3.01	2.12	2.265	2.121	0.132	1.33057012	0.39271754
Infliximab	Dizziness	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	391	99063	22111	2884590	0.503	0.462	0.546	0.497	204.667	0.487	0	-0.9867981	-0.6871651
Infliximab	Dizziness postural	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	3	756	22499	2982897	0.307	0.119	0.679	0.287	5.292	0.287	0.021	-0.7513439	-1.1809075
Infliximab	Double stranded DNA antibody	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	18	11	22484	2983642	24.159	16.016	35.242	81.544	446.468	81.67	0	3.95365848	3.18465698
Infliximab	Douglas abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	4	22501	2983649	1.205	0.278	3.776	7.666	4.719	7.666	0.03	0.93614837	0.18647957
Infliximab	Dresslers syndrome	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	1	38	22501	2983615	1.008	0.233	3.148	2.541	0.92	2.541	0.337	0.61961696	0.00796817
Infliximab	Drop attacks	Muscle tone abnormal	Neuromuscular disorders	Nerv	1968-2006	1	44	22501	2983609	0.753	0.174	2.35	1.107	0.01	1.107	0.92	0.5703131	-0.2836901
Infliximab	Drowning	Death and sudden death	Fatal outcomes	Genrl	1968-2006	2	227	22500	2983426	0.557	0.181	1.397	0.582	0.582	0.582	0.446	0.13352056	-0.58519
Infliximab	Drug abuser	Drug and chemical abuse	Lifestyle issues	SocCi	1968-2006	5	7554	22497	2976099	0.045	0.022	0.087	0.041	113.399	0.041	1.765e-26	-3.2770653	-3.1010928
Infliximab	Drug administration error	Maladministrations	Medication errors	Inj&P	1968-2006	17	9831	22485	2973822	0.262	0.174	0.381	0.256	37.637	0.25	8.52e-10	-2.0690071	-1.3394108
Infliximab	Drug dependence	Substance-related disorders	Psychiatric disorders NEC	Psych	1968-2006	6	16240	22496	2967413	0.043	0.021	0.078	0.039	145.51	0.039	1.662e-33	-4.149247	-3.1465552
Infliximab	Drug dispensing error	Medication errors NEC	Medication errors	Inj&P	1968-2006	1	949	22501	2982704	0.1	0.023	0.313	0.071	12.346	0.07	0.0004419	-2.031185	-2.3025851
Infliximab	Drug dose omission	Maladministrations	Medication errors	Inj&P	1968-2006	2	567	22500	2983086	0.264	0.085	0.662	0.232	4.975	0.232	0.026	-0.8209776	-1.3318062
Infliximab	Drug effect decreased	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	115	12776	22387	2970877	0.775	0.663	0.901	0.773	7.571	0.772	0.006	0.2337228	-0.2548922
Infliximab	Drug effect increased	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	2	2818	22500	2980835	0.422	0.137	1.058	0.412	1.696	0.412	0.193	-2.893773	-0.86275
Infliximab	Drug eruption	Dermatitis ascribed to specific agent	Epidermal and dermal conditions	Skin	1968-2006	14	1659	22488	2981994	0.548	0.349	0.826	0.546	5.216	0.546	0.022	0.1379143	-0.60148
Infliximab	Drug exposure before pregnancy	Medication errors due to accidental exposures	Medication errors	Inj&P	1968-2006	1	297	22501	2983356	0.231	0.053	0.721	0.182	3.737	0.182	0.053	-0.7027946	-1.4653376
Infliximab	Drug exposure during pregnancy	Medication errors due to accidental exposures	Medication errors	Inj&P	1968-2006	178	12947	22324	2970706	0.667	0.589	0.753	0.661	31.036	0.655	2.533e-8	0.83378486	-0.4049652
Infliximab	Drug hypersensitivity	Allergies to foods, food additives, drugs and other chemicals	Allergic conditions	Immun	1968-2006	87	6228	22415	2977425	0.911	0.762	1.083	0.915	0.675	0.915	0.411	0.85253114	-0.0932124
Infliximab	Drug ineffective	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	459	181189	22043	2802464	0.489	0.453	0.528	0.483	262.574	0.472	0	-1.6658564	-0.7153928
Infliximab	Drug ineffective for unapproved indication	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	1	315	22501	2983338	0.235	0.054	0.733	0.183	3.613	0.183	0.057	-0.7617511	-1.4481698
Infliximab	Drug interaction	Interactions	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	182	36224	22320	2947429	0.601	0.531	0.678	0.596	49.888	0.592	1.628e-12	-0.608212	-0.5091603
Infliximab	Drug interaction potentiation	Interactions	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	1	337	22501	2983316	0.275	0.063	0.857	0.222	2.692	0.222	0.101	-0.8306841	-1.2909842
Infliximab	Drug intolerance	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	21	1114	22481	2982539	0.925	0.641	1.301	0.948	0.059	0.948	0.808	1.2007599	-0.0779615
Infliximab	Drug level above therapeutic	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	4	13034	22498	2970619	0.124	0.054	0.252	0.113	28.168	0.112	1.112e-7	-4.3186464	-2.0874737
Infliximab	Drug level decreased	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	3	850	22499	2982803	0.181	0.07	0.399	0.161	13.123	0.161	0.0002917	-0.8958415	-1.7092582
Infliximab	Drug level increased	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	2	2719	22500	2980934	0.043	0.014	0.109	0.035	54.277	0.034	1.741e-13	-2.8445392	-3.1465552
Infliximab	Drug resistance	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	6	487	22496	2983166	0.69	0.348	1.256	0.716	0.658	0.716	0.417	0.56661309	-0.3710637
Infliximab	Drug screen positive	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	4	1511	22498	2982142	0.144	0.063	0.293	0.13	23.181	0.13	1.474e-6	-1.3149402	-1.937942
Infliximab	Drug specific antibody present	Therapeutic drug monitoring analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	16	149	22486	2983504	3.908	2.562	5.772	5.842	54.417	5.844	1.621e-13	2.9162244	1.36302573
Infliximab	Drug tolerance decreased	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	6	658	22496	2982995	0.844	0.426	1.537	0.909	0.054	0.909	0.817	0.2184075	-0.1696028
Infliximab	Drug toxicity	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	48	10687	22454	2972966	0.287	0.225	0.361	0.281	88.568	0.279	4.912e-21	-0.7474609	-1.2482731
Infliximab	Drug withdrawal convulsions	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	2	177	22500	2983476	0.664	0.215	1.666	0.746	0.17	0.746	0.68	0.34760889	-0.4094731
Infliximab	Drug withdrawal syndrome	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	10	27168	22492	2956485	0.034	0.02	0.055	0.032	304.01	0.031	0	-4.240107	-3.3813948
Infliximab	Dry eye	Lacrimal disorders	Eye disorders NEC	Eye	1968-2006	13	3364	22489	2980289	0.514	0.322	0.787	0.509	6.013	0.508	0.014	-0.9208886	-0.665532
Infliximab	Dry gangrene	Skin ischaemic conditions	Skin vascular abnormalities	Skin	1968-2006	1	28	22501	2983625	0.945	0.219	2.952	2.047	0.519	2.047	0.471	0.70572945	-0.0565704
Infliximab	Dry mouth	Oral dryness and saliva altered	Salivary gland conditions	Gastr	1968-2006	19	17764	22483	2965889	0.16	0.109	0.229	0.154	88.261	0.153	5.736e-21	-2.7648118	-1.8325815
Infliximab	Dry skin	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	10	10422	22492	2973231	0.228	0.134	0.368	0.218	27.88	0.218	1.291e-7	-2.8618189	-1.4784097
Infliximab	Dry throat	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	8	820	22494	2982833	0.707	0.39	1.201	0.73	0.793	0.73	0.373	0.31112621	-0.3467246
Infliximab	Dubin-Johnson syndrome	Inborn errors of bilirubin metabolism	Metabolic and nutritional disorders congenital	Cong	1968-2006	1	2	22501	2983651	1.339	0.307	4.234	48.063	22.717	48.063	1.877e-6	0.95711984	0.29192307
Infliximab	Ductus arteriosus premature closure	Arterial disorders congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	17	22501	2983636	1.04	0.24	3.249	2.94	1.216	2.94	0.27	0.80679534	0.03922071
Infliximab	Duodenal fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	1	7	22501	2983646	1.197	0.276	3.75	7.659	4.377	7.659	0.036	0.90525186	0.17981843
Infliximab	Duodenal neoplasm	Gastrointestinal neoplasms malignancy unspecified NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	7	22500	2983646	1.924	0.619	4.886	12.708	15.741	12.708	0.00007262	1.48006086	0.65440635
Infliximab	Duodenal operation	Small intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	3	22501	2983650	1.347	0.308	4.264	40.047	26.245	40.047	3.008e-7	0.946596	0.2978799
Infliximab	Duodenal perforation	Duodenal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	2	102	22500	2983551	1.016	0.329	2.547	1.494	0.307	1.494	0.579	0.74343498	0.01587335
Infliximab	Duodenal polyp	Benign neoplasms gastrointestinal (excl oral cavity)	Benign neoplasms gastrointestinal	Gastr	1968-2006	1	24	22501	2983629	1.064	0.246	3.326	3.276	1.478	3.276	0.224	0.74166694	0.06203539
Infliximab	Duodenal stenosis	Duodenal and small intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	1	48	22501	2983605	0.752	0.174	2.347	1.102	0.009	1.102	0.923	0.53835564	-0.285019
Infliximab	Duodenal ulcer	Duodenal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	14	2416	22488	2981237	0.633	0.404	0.956	0.637	2.849	0.637	0.091	-0.367347	-0.4572849
Infliximab	Duodenal ulcer haemorrhage	Duodenal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	11	1460	22491	2982193	0.884	0.532	1.4	0.923	0.069	0.923	0.793	-0.0128536	-0.1232982
Infliximab	Duodenal ulcer perforation	Duodenal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	5	860	22497	2982793	0.651	0.309	1.244	0.678	0.763	0.678	0.382	-0.3283257	-0.4292456
Infliximab	Duodenitis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	9	983	22493	2982670	0.788	0.45	1.303	0.819	0.351	0.819	0.553	0.235864	-0.2382572
Infliximab	Duodenitis haemorrhagic	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	1	23	22501	2983630	0.995	0.23	3.107	2.462	0.828	2.462	0.363	0.75079293	-0.0050125
Infliximab	Dupuytrens contracture	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	2	51	22500	2983602	1.365	0.442	3.424	2.821	2.24	2.822	0.135	1.09205332	0.31115443
Infliximab	Dwarfism	Metabolic bone disorders	Bone disorders (excl congenital and fractures)	Musc	1968-2006	1	10	22501	2983643	1.262	0.291	3.963	10.604	8.108	10.604	0.004	0.87500312	0.23269776
Infliximab	Dysaesthesia	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	13	294	22489	2983359	1.956	1.226	2.995	2.311	9.198	2.312	0.002	2.07478509	0.67090157
Infliximab	Dysarthria	Speech and language abnormalities	Neurological disorders NEC	Nerv	1968-2006	42	6287	22460	2977366	0.537	0.415	0.686	0.532	17.087	0.531	0.00003571	-0.1837926	-0.6217572
Infliximab	Dyscalculia	Cortical dysfunction NEC	Neurological disorders NEC	Nerv	1968-2006	2	26	22500	2983627	1.603	0.519	4.029	4.916	5.275	4.916	0.022	1.29959284	0.47187687
Infliximab	Dysentery	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	53	22500	2983600	1.433	0.464	3.597	3.285	2.912	3.286	0.088	1.07667128	0.35977015
Infliximab	Dysfunctional uterine bleeding	Menstruation and uterine bleeding NEC	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	2	541	22500	2983112	0.221	0.071	0.553	0.191	6.824	0.19	0.009	-0.7665643	-1.5095926
Infliximab	Dysgeusia	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	21	20102	22481	2963551	0.163	0.113	0.229	0.158	95.004	0.157	1.9e-22	-2.8055412	-1.8140051
Infliximab	Dysgraphia	Cortical dysfunction NEC	Neurological disorders NEC	Nerv	1968-2006	3	450	22499	2983203	0.417	0.162	0.921	0.402	2.591	0.402	0.107	-0.1455552	-0.8746691
Infliximab	Dyshidrosis	Apocrine and eccrine gland disorders	Skin appendage conditions	Skin	1968-2006	5	70	22497	2983583	2.458	1.164	4.708	5.035	13.506	5.037	0.0002378	1.93124919	0.89934801
Infliximab	Dyskinesia	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	23	6768	22479	2976885	0.379	0.267	0.525	0.371	24.254	0.371	8.443e-7	-1.1249438	-0.9702191
Infliximab	Dyslipidaemia	Lipid metabolism and deposit disorders NEC	Lipid metabolism disorders	Metab	1968-2006	1	419	22501	2983234	0.271	0.062	0.846	0.222	2.743	0.221	0.098	-1.0620062	-1.3056365
Infliximab	Dysmenorrhoea	Menstruation and uterine bleeding NEC	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	4	2346	22498	2981307	0.235	0.103	0.478	0.217	11.201	0.216	0.001	-1.906537	-1.4481698
Infliximab	Dyspareunia	Sexual function and fertility disorders NEC	Sexual function and fertility disorders	Repro	1968-2006	2	777	22500	2982876	0.544	0.176	1.364	0.564	0.657	0.564	0.418	-1.1983605	-0.608806
Infliximab	Dyspepsia	Dyspeptic signs and symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	47	24795	22455	2958858	0.313	0.245	0.394	0.307	73.657	0.305	9.294e-18	-1.9844242	-1.1615521
Infliximab	Dysphagia	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	125	14987	22377	2968666	0.953	0.821	1.101	0.957	0.243	0.956	0.622	0.12479374	-0.0481404
Infliximab	Dysphasia	Speech and language abnormalities	Neurological disorders NEC	Nerv	1968-2006	3	479	22499	2983174	0.425	0.165	0.94	0.415	2.449	0.415	0.118	-0.2151859	-0.8556661
Infliximab	Dysphonia	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	43	6224	22459	2977429	0.652	0.505	0.831	0.65	8.006	0.65	0.005	-0.1366877	-0.4277107
Infliximab	Dysphoria	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	3	310	22499	2983343	0.579	0.225	1.28	0.604	0.78	0.604	0.377	0.24790992	-0.5464528
Infliximab	Dysplasia	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	5	82	22497	2983571	2.066	0.979	3.949	3.471	7.796	3.472	0.005	1.85054803	0.72561437
Infliximab	Dysplastic naevus syndrome	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	1	16	22501	2983637	1.062	0.245	3.317	3.272	1.456	3.272	0.228	0.81634411	0.06015392
Infliximab	Dyspnoea	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	1420	95484	21082	2888169	1.817	1.739	1.898	1.852	557.285	1.917	0	0.91039334	0.59718679
Infliximab	Dyspnoea at rest	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	3	73	22499	2983580	1.494	0.581	3.305	2.492	2.561	2.493	0.11	1.33938614	0.40145709
Infliximab	Dyspnoea exacerbated				1968-2006	20	1395	22482	2982258	0.975	0.669	1.382	1.005	0	1.005	0.984	0.84578172	-0.0253178
Infliximab	Dyspnoea exertional	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	73	3569	22429	2980084	1.531	1.259	1.847	1.577	14.898	1.58	0.0001135	1.37612115	0.42592112
Infliximab	Dyspnoea paroxysmal nocturnal	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	3	265	22499	2983388	0.897	0.349	1.984	1.075	0.015	1.075	0.902	0.40115736	-0.1086994
Infliximab	Dysstasia	Cerebellar coordination and balance disturbances	Neurological disorders NEC	Nerv	1968-2006	9	1612	22493	2982041	0.303	0.173	0.501	0.292	15.305	0.292	0.00009145	-0.4048902	-1.1940225
Infliximab	Dysthymic disorder	Depressive disorders	Depressed mood disorders and disturbances	Psych	1968-2006	1	119	22501	2983534	0.521	0.12	1.625	0.553	0.365	0.553	0.546	0.06444279	-0.6520052
Infliximab	Dystonia	Dystonias	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	5	5033	22497	2978620	0.175	0.083	0.333	0.16	21.729	0.16	0.00000314	-2.7029827	-1.7429693
Infliximab	Dysuria	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	31	7686	22471	2975967	0.552	0.409	0.734	0.55	11.37	0.549	0.001	-0.8914236	-0.5942072
Infliximab	Ear canal stenosis	External ear disorders NEC	External ear disorders (excl congenital)	Ear	1968-2006	1	8	22501	2983645	1.131	0.261	3.536	4.459	2.535	4.459	0.111	0.89509832	0.1231022
Infliximab	Ear discomfort	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	3	515	22499	2983138	0.386	0.15	0.854	0.372	3.164	0.372	0.075	-0.2971973	-0.9519179
Infliximab	Ear disorder	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	6	1866	22496	2981787	0.619	0.312	1.127	0.632	1.251	0.632	0.263	-1.1124784	-0.47965
Infliximab	Ear haemorrhage	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	3	167	22499	2983486	0.948	0.368	2.096	1.164	0.068	1.164	0.794	0.80479765	-0.0534008
Infliximab	Ear infection	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	20	919	22482	2982734	1.234	0.847	1.749	1.299	1.339	1.299	0.247	1.37586598	0.21026093
Infliximab	Ear infection staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.367	0.312	4.342	163.009	40.948	163.009	1.564e-10	0.967721	0.31261856
Infliximab	Ear lobe infection	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	1	4	22501	2983649	1.262	0.291	3.965	15.044	8.197	15.044	0.004	0.93614837	0.23269776
Infliximab	Ear neoplasm malignant	Aural neoplasms malignant and unspecified	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	2	1	22500	2983652	2.224	0.693	5.972	63.379	47.93	63.456	4.417e-12	1.54208236	0.79930738
Infliximab	Ear operation	Head, neck and oral cavity therapeutic procedures NEC	Head and neck therapeutic procedures	Surg	1968-2006	1	13	22501	2983640	1.164	0.269	3.644	5.149	3.298	5.149	0.069	0.84537553	0.15186235
Infliximab	Ear pain	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	19	2413	22483	2981240	0.865	0.588	1.237	0.885	0.281	0.885	0.596	0.04656671	-0.1450258
Infliximab	Ear pruritus	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	1	59	22501	2983594	0.69	0.16	2.153	0.914	0.008	0.914	0.93	0.453956	-0.3710637
Infliximab	Ear tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.343	0.308	4.251	32.239	24.974	32.239	5.811e-7	0.967721	0.29490592
Infliximab	Eating disorder	Eating disorders NEC	Eating disorders and disturbances	Psych	1968-2006	17	1361	22485	2982292	0.727	0.483	1.059	0.735	1.587	0.735	0.208	0.65829409	-0.3188288
Infliximab	Eating disorder symptom	Eating disorder symptoms NEC	Eating disorders and disturbances	Psych	1968-2006	1	46	22501	2983607	0.823	0.19	2.568	1.361	0.097	1.361	0.755	0.5542459	-0.1947991
Infliximab	Ecchymosis	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	30	9177	22472	2974476	0.797	0.586	1.063	0.804	1.415	0.804	0.234	-1.1886627	-0.2269006
Infliximab	Echocardiogram abnormal	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	7	643	22495	2983010	0.821	0.436	1.439	0.869	0.133	0.869	0.716	0.43660791	-0.1972322
Infliximab	Eclampsia	Hypertension associated disorders of pregnancy	Maternal complications of pregnancy	Preg	1968-2006	4	202	22498	2983451	1.157	0.505	2.351	1.452	0.548	1.452	0.459	0.96504161	0.14583045
Infliximab	Economic problem	Economic circumstances	Economic and housing issues	SocCi	1968-2006	1	561	22501	2983092	0.142	0.033	0.444	0.104	7.832	0.104	0.005	-1.3914914	-1.9519282
Infliximab	Ectopic antidiuretic hormone secretion	Ectopic hormone secretion syndromes associated with neoplasias	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	2	22501	2983651	1.378	0.314	4.387	169.479	54.136	169.479	1.871e-13	0.95711984	0.32063317
Infliximab	Ectopic pregnancy	Maternal complications of pregnancy NEC	Maternal complications of pregnancy	Preg	1968-2006	5	605	22497	2983048	0.456	0.216	0.87	0.447	3.334	0.447	0.068	0.09718004	-0.7852625
Infliximab	Eczema	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	56	3024	22446	2980629	1.934	1.546	2.394	2.041	28.377	2.044	9.985e-8	1.23233763	0.6595904
Infliximab	Eczema asteatotic	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	1	30	22501	2983623	0.982	0.227	3.067	2.309	0.736	2.309	0.391	0.68809089	-0.018164
Infliximab	Eczema infected	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	4	29	22498	2983624	2.83	1.225	5.851	8.785	24.926	8.786	5.959e-7	1.99259375	1.04027671
Infliximab	Eczema nummular	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	3	27	22499	2983626	2.176	0.843	4.84	6.846	12.459	6.846	0.0004161	1.6968834	0.77748833
Infliximab	Eczema vesicular	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	2	5	22500	2983648	2.126	0.673	5.542	24.961	33.32	24.969	7.817e-9	1.50043989	0.75424228
Infliximab	Educational problem	Educational issues	Lifestyle issues	SocCi	1968-2006	2	349	22500	2983304	0.344	0.112	0.864	0.321	2.878	0.32	0.09	-0.2849586	-1.0671136
Infliximab	Effusion	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	126	22500	2983527	0.855	0.277	2.143	1.099	0.017	1.099	0.896	0.60459304	-0.1566538
Infliximab	Egobronchophony	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	1	1	22501	2983652	1.339	0.307	4.233	33.612	22.855	33.612	1.747e-6	0.967721	0.29192307
Infliximab	Ejection fraction abnormal	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	1025	22500	2982628	0.348	0.113	0.872	0.326	2.793	0.325	0.095	-1.5452983	-1.0555528
Infliximab	Ejection fraction decreased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	47	1608	22455	2982045	1.517	1.188	1.914	1.58	9.596	1.581	0.002	1.83045606	0.4167347
Infliximab	Electrocardiogram P wave abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	41	22501	2983612	0.827	0.191	2.581	1.388	0.105	1.388	0.746	0.59475445	-0.1899506
Infliximab	Electrocardiogram PR prolongation	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	91	22501	2983562	0.567	0.131	1.771	0.635	0.208	0.635	0.649	0.23324737	-0.567396
Infliximab	Electrocardiogram PR shortened	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	48	22501	2983605	0.927	0.215	2.895	1.932	0.427	1.932	0.513	0.53835564	-0.0758017
Infliximab	Electrocardiogram Q wave abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	57	22499	2983596	1.572	0.61	3.476	2.82	3.209	2.821	0.073	1.4539563	0.45234869
Infliximab	Electrocardiogram Q waves	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	112	22499	2983541	1.411	0.548	3.12	2.258	1.956	2.259	0.162	1.09317465	0.34429867
Infliximab	Electrocardiogram QRS complex abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	158	22500	2983495	0.81	0.263	2.031	1.007	0	1.007	0.992	0.4380853	-0.210721
Infliximab	Electrocardiogram QRS complex prolonged	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	4	721	22498	2982932	0.384	0.168	0.78	0.371	4.213	0.371	0.04	-0.373371	-0.9571127
Infliximab	Electrocardiogram QT corrected interval prolonged	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	1275	22500	2982378	0.112	0.036	0.282	0.091	17.799	0.091	0.00002455	-1.8268584	-2.1892564
Infliximab	Electrocardiogram QT prolonged	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	4446	22499	2979207	0.071	0.027	0.157	0.06	43.597	0.06	4.034e-11	-3.1132164	-2.6450754
Infliximab	Electrocardiogram ST segment	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	11	22501	2983642	1.237	0.285	3.88	9.394	6.231	9.396	0.013	0.86505951	0.21268909
Infliximab	Electrocardiogram ST segment abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	5	456	22497	2983197	0.767	0.364	1.465	0.821	0.19	0.821	0.663	0.41986163	-0.2652685
Infliximab	Electrocardiogram ST segment depression	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	11	1078	22491	2982575	0.959	0.577	1.518	1.012	0.001	1.012	0.97	0.37959366	-0.0418642
Infliximab	Electrocardiogram ST segment elevation	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	13	1231	22489	2982422	0.974	0.611	1.491	1.021	0.005	1.021	0.942	0.42970683	-0.026344
Infliximab	Electrocardiogram ST-T change	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	14	272	22488	2983381	2.328	1.484	3.514	2.87	15.778	2.872	0.00007122	2.24478676	0.84500953
Infliximab	Electrocardiogram ST-T segment abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	94	22500	2983559	0.819	0.266	2.054	1.025	0.001	1.025	0.972	0.79285204	-0.1996712
Infliximab	Electrocardiogram T wave abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	6	379	22496	2983274	0.726	0.367	1.322	0.76	0.443	0.76	0.506	0.83959006	-0.3202053
Infliximab	Electrocardiogram T wave amplitude decreased	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	5	173	22497	2983480	1.614	0.765	3.083	2.224	3.238	2.224	0.072	1.35223282	0.47871557
Infliximab	Electrocardiogram T wave amplitude increased	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	26	22500	2983627	1.558	0.505	3.915	4.299	4.524	4.3	0.033	1.29959284	0.44340295
Infliximab	Electrocardiogram T wave inversion	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	14	1100	22488	2982553	1.052	0.671	1.588	1.108	0.143	1.108	0.705	0.67230788	0.05069311
Infliximab	Electrocardiogram abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	25	5056	22477	2978597	0.738	0.527	1.01	0.743	2.18	0.742	0.14	-0.5994628	-0.3038115
Infliximab	Electrocardiogram change	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	271	22499	2983382	0.71	0.276	1.57	0.783	0.181	0.783	0.671	0.37975943	-0.3424903
Infliximab	Electrocardiogram poor R-wave progression	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	110	22499	2983543	1.179	0.458	2.607	1.636	0.71	1.636	0.4	1.10482934	0.16466662
Infliximab	Electrocardiogram repolarisation abnormality	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	119	22501	2983534	0.452	0.104	1.411	0.437	0.708	0.436	0.4	0.06444279	-0.7940731
Infliximab	Electroencephalogram abnormal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	12	3286	22490	2980367	0.41	0.252	0.637	0.402	10.549	0.402	0.001	-0.9949298	-0.8915981
Infliximab	Electrolyte depletion	Electrolyte imbalance NEC	Electrolyte and fluid balance conditions	Metab	1968-2006	1	153	22501	2983500	0.876	0.203	2.734	1.64	0.232	1.64	0.63	-0.1170858	-0.1323892
Infliximab	Electrolyte imbalance	Electrolyte imbalance NEC	Electrolyte and fluid balance conditions	Metab	1968-2006	17	1920	22485	2981733	0.826	0.549	1.204	0.844	0.478	0.844	0.489	0.20405014	-0.1911605
Infliximab	Electromechanical dissociation	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	2	534	22500	2983119	0.259	0.084	0.648	0.227	5.157	0.227	0.023	-0.7515571	-1.3509272
Infliximab	Electromyogram abnormal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	6	168	22496	2983485	2.213	1.117	4.033	3.498	9.679	3.499	0.002	1.59326746	0.79434906
Infliximab	Electrophoresis protein abnormal	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	1	26	22501	2983627	0.996	0.23	3.11	2.497	0.832	2.497	0.362	0.72358631	-0.004008
Infliximab	Embolic stroke	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	2	231	22500	2983422	0.567	0.184	1.421	0.596	0.533	0.596	0.465	0.11769056	-0.567396
Infliximab	Embolism	Non-site specific embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	27	3085	22475	2980568	0.757	0.548	1.025	0.764	1.961	0.764	0.161	0.19247873	-0.278392
Infliximab	Embolism infective	Vascular infections	Infections - pathogen class unspecified	Infec	1968-2006	1	3	22501	2983650	1.266	0.292	3.978	15.684	8.602	15.684	0.003	0.946596	0.23586232
Infliximab	Embolism venous	Non-site specific embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	58	22501	2983595	0.796	0.184	2.484	1.256	0.052	1.256	0.819	0.46142791	-0.2281561
Infliximab	Emotional disorder	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	4	12190	22498	2971463	0.081	0.035	0.165	0.072	47.757	0.072	4.825e-12	-4.2226979	-2.5133061
Infliximab	Emotional distress	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	14	4187	22488	2979466	0.245	0.157	0.37	0.237	34.22	0.237	4.922e-9	-1.125933	-1.4064971
Infliximab	Emphysema	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	49	1465	22453	2982188	2.471	1.945	3.104	2.701	49.002	2.705	2.557e-12	2.00788379	0.90462293
Infliximab	Empty sella syndrome	Hypothalamic and pituitary disorders NEC	Hypothalamus and pituitary gland disorders	Endo	1968-2006	1	37	22501	2983616	0.944	0.218	2.948	2.06	0.512	2.061	0.474	0.62800058	-0.0576291
Infliximab	Empyema	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	30	281	22472	2983372	5.033	3.695	6.742	6.875	128.739	6.883	7.734e-30	3.20859174	1.61601623
Infliximab	Enanthema	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	1	123	22501	2983530	0.546	0.126	1.705	0.593	0.273	0.593	0.601	0.04186259	-0.6051363
Infliximab	Encephalitis	Encephalitis NEC	Central nervous system infections and inflammations	Nerv	1968-2006	35	1192	22467	2982461	2.812	2.117	3.676	3.178	49.034	3.182	2.516e-12	1.81020885	1.03389597
Infliximab	Encephalitis herpes	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	12	165	22490	2983488	3.443	2.115	5.367	5.249	36.239	5.252	1.745e-9	2.47234994	1.23634318
Infliximab	Encephalitis viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	3	187	22499	2983466	0.869	0.338	1.92	1.026	0.002	1.026	0.964	0.71274679	-0.1404122
Infliximab	Encephalomalacia	Structural brain disorders NEC	Structural brain disorders	Nerv	1968-2006	1	100	22501	2983553	0.502	0.116	1.568	0.519	0.444	0.519	0.505	0.1768059	-0.6891552
Infliximab	Encephalopathy	Encephalopathies NEC	Encephalopathies	Nerv	1968-2006	35	5809	22467	2977844	0.617	0.465	0.807	0.615	8.335	0.614	0.004	-0.3273523	-0.4828863
Infliximab	Endocarditis	Cardiac infections	Infections - pathogen class unspecified	Infec	1968-2006	28	784	22474	2982869	3.067	2.232	4.131	3.643	49.064	3.647	2.478e-12	2.02340523	1.12069989
Infliximab	Endocarditis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	12	165	22490	2983488	3.537	2.172	5.516	5.291	38.464	5.294	5.576e-10	2.47234994	1.26327891
Infliximab	Endocarditis enterococcal	Enterococcal infections	Bacterial infectious disorders	Infec	1968-2006	2	35	22500	2983618	1.69	0.547	4.255	5.801	7.003	5.802	0.008	1.22139582	0.52472853
Infliximab	Endocarditis staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	4	64	22498	2983589	2.048	0.894	4.168	4.05	7.91	4.051	0.005	1.71746262	0.71686371
Infliximab	Endocrine disorder	Endocrine disorders NEC	Endocrine and glandular disorders NEC	Endo	1968-2006	1	245	22501	2983408	0.628	0.145	1.959	0.758	0.074	0.758	0.786	-0.5175524	-0.4652151
Infliximab	Endocrine neoplasm	Endocrine neoplasms malignant and unspecified NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	7	22501	2983646	1.272	0.293	3.998	13.212	9.016	13.212	0.003	0.90525186	0.24059046
Infliximab	Endodontic procedure	Dental and gingival therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	1	128	22501	2983525	0.52	0.12	1.624	0.545	0.366	0.545	0.545	0.01412534	-0.6539265
Infliximab	Endometrial atrophy	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	24	22501	2983629	0.899	0.208	2.808	1.763	0.315	1.763	0.575	0.74166694	-0.1064722
Infliximab	Endometrial cancer	Endometrial neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	11	906	22491	2982747	1.088	0.655	1.722	1.169	0.258	1.169	0.612	0.59841668	0.08434115
Infliximab	Endometrial cancer metastatic	Endometrial neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	22	22500	2983631	1.611	0.521	4.049	5.08	5.429	5.08	0.02	1.33575551	0.4768551
Infliximab	Endometrial cancer stage I	Endometrial neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	3	48	22499	2983605	1.609	0.625	3.56	2.924	3.576	2.925	0.059	1.52263875	0.47561287
Infliximab	Endometrial sarcoma	Endometrial neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	7	22500	2983646	1.91	0.615	4.845	12.002	15.003	12.002	0.0001073	1.48006086	0.64710324
Infliximab	Endometriosis	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	8	413	22494	2983240	1.089	0.601	1.848	1.2	0.261	1.2	0.61	1.10531723	0.08525984
Infliximab	Endometritis	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	112	22501	2983541	0.499	0.115	1.558	0.511	0.459	0.511	0.498	0.10482889	-0.6951492
Infliximab	Endophthalmitis	Ocular infections, inflammations and associated manifestations	Ocular infections, irritations and inflammations	Eye	1968-2006	8	268	22494	2983385	1.522	0.84	2.585	1.822	2.844	1.823	0.092	1.54262335	0.42002526
Infliximab	Endoscopic retrograde cholangiopancreatography abnormal	Hepatobiliary imaging procedures	Hepatobiliary investigations	Inv	1968-2006	1	10	22501	2983643	1.237	0.285	3.882	10.082	6.264	10.082	0.012	0.87500312	0.21268909
Infliximab	Endoscopy large bowel abnormal	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	1	3	22501	2983650	1.265	0.292	3.974	15.519	8.469	15.519	0.004	0.946596	0.23507212
Infliximab	Endoscopy upper gastrointestinal tract abnormal	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	2	47	22500	2983606	1.414	0.458	3.548	3.14	2.719	3.14	0.099	1.12331827	0.34642257
Infliximab	Energy increased	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	351	22501	2983302	0.221	0.051	0.689	0.171	4.011	0.171	0.045	-0.872896	-1.5095926
Infliximab	Enteritis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	4	711	22498	2982942	0.53	0.231	1.076	0.537	1.589	0.537	0.207	-0.3564646	-0.6348783
Infliximab	Enteritis infectious	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	37	22500	2983616	1.488	0.482	3.737	3.662	3.554	3.662	0.059	1.20457957	0.39743294
Infliximab	Enterobacter bacteraemia	Enterobacter infections	Bacterial infectious disorders	Infec	1968-2006	3	16	22499	2983637	2.431	0.937	5.462	10.021	20.522	10.022	5.896e-6	1.79730948	0.8883027
Infliximab	Enterobacter infection	Enterobacter infections	Bacterial infectious disorders	Infec	1968-2006	14	245	22488	2983408	2.355	1.501	3.554	2.88	16.261	2.881	0.00005517	2.34075531	0.85654073
Infliximab	Enterobacter pneumonia	Enterobacter infections	Bacterial infectious disorders	Infec	1968-2006	2	15	22500	2983638	1.766	0.571	4.454	6.894	9.103	6.894	0.003	1.40130667	0.5687171
Infliximab	Enterobacter sepsis	Enterobacter infections	Bacterial infectious disorders	Infec	1968-2006	2	21	22500	2983632	1.73	0.559	4.357	6.618	7.996	6.618	0.005	1.34493959	0.54812141
Infliximab	Enterococcal bacteraemia	Enterococcal infections	Bacterial infectious disorders	Infec	1968-2006	7	230	22495	2983423	1.856	0.984	3.254	2.489	5.769	2.489	0.016	1.51707138	0.61842363
Infliximab	Enterococcal infection	Enterococcal infections	Bacterial infectious disorders	Infec	1968-2006	36	679	22466	2982974	2.369	1.791	3.085	2.628	33.824	2.632	6.034e-9	2.53107376	0.86246793
Infliximab	Enterococcal sepsis	Enterococcal infections	Bacterial infectious disorders	Infec	1968-2006	6	64	22496	2983589	2.668	1.345	4.872	4.976	16.726	4.979	0.00004319	2.18864657	0.98132913
Infliximab	Enterocolitis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	5	616	22497	2983037	0.716	0.339	1.367	0.755	0.386	0.755	0.535	0.07598926	-0.3340751
Infliximab	Enterocolitis haemorrhagic	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	5	760	22497	2982893	0.707	0.335	1.35	0.745	0.428	0.745	0.513	-0.1760488	-0.3467246
Infliximab	Enterocolitis infectious	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	73	22501	2983580	0.589	0.136	1.838	0.68	0.152	0.68	0.697	0.35321934	-0.5293291
Infliximab	Enterocolonic fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	3	4	22499	2983649	2.943	1.085	7.459	52.043	49.586	52.043	1.898e-12	1.91547742	1.07942947
Infliximab	Enterocutaneous fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	15	34	22487	2983619	9.653	5.08	17.705	20.94	177.279	20.952	1.904e-40	3.53835749	2.26726875
Infliximab	Enterovesical fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	7	39	22495	2983614	3.874	2.028	7.001	9.798	44.606	9.802	2.41e-11	2.56225789	1.35428756
Infliximab	Enthesopathy	Tendon disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	1	20	22501	2983633	1.069	0.247	3.342	3.265	1.542	3.265	0.214	0.77852244	0.06672363
Infliximab	Enzyme abnormality	Metabolic disorders NEC	Metabolism disorders NEC	Metab	1968-2006	2	973	22500	2982680	0.528	0.171	1.324	0.542	0.753	0.542	0.385	-1.4791409	-0.638659
Infliximab	Eosinophil count	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	28	22501	2983625	0.843	0.195	2.632	1.46	0.141	1.461	0.707	0.70572945	-0.1707883
Infliximab	Eosinophil count abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	38	22501	2983615	0.893	0.207	2.788	1.718	0.288	1.718	0.592	0.61961696	-0.1131687
Infliximab	Eosinophil count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	167	22501	2983486	0.494	0.114	1.543	0.502	0.478	0.502	0.49	-0.1856664	-0.7052198
Infliximab	Eosinophil count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	11	1356	22491	2982297	0.559	0.336	0.884	0.559	3.773	0.559	0.052	0.08387125	-0.5816058
Infliximab	Eosinophil percentage increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	133	22501	2983520	0.462	0.107	1.442	0.451	0.647	0.451	0.421	-0.0130888	-0.7721904
Infliximab	Eosinophilia	Eosinophilic disorders	White blood cell disorders	Blood	1968-2006	25	7029	22477	2976624	0.671	0.479	0.918	0.673	3.93	0.673	0.047	-1.0633725	-0.3989861
Infliximab	Eosinophilic myocarditis	Noninfectious myocarditis	Myocardial disorders	Card	1968-2006	1	48	22501	2983605	0.88	0.204	2.747	1.651	0.243	1.651	0.622	0.53835564	-0.1278334
Infliximab	Eosinophilic pneumonia	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	4	184	22498	2983469	0.948	0.414	1.927	1.102	0.037	1.102	0.847	1.04362046	-0.0534008
Infliximab	Eosinophilic pustular folliculitis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	5	22501	2983648	1.284	0.296	4.037	13.356	10.291	13.356	0.001	0.92577585	0.24998021
Infliximab	Ependymoma	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	18	22501	2983635	1.033	0.239	3.226	2.905	1.148	2.905	0.284	0.79730935	0.03246719
Infliximab	Ephelides	Hyperpigmentation disorders	Pigmentation disorders	Skin	1968-2006	1	30	22501	2983623	0.948	0.219	2.96	2.072	0.533	2.073	0.465	0.68809089	-0.0534008
Infliximab	Epicondylitis	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	1	100	22501	2983553	0.596	0.138	1.861	0.689	0.134	0.689	0.714	0.1768059	-0.5175146
Infliximab	Epidemic pleurodynia	Coxsackie viral infections	Viral infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.331	0.305	4.205	107.889	20.218	107.889	0.00000691	0.967721	0.28593054
Infliximab	Epidermal necrosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	2	77	22500	2983576	1.108	0.359	2.779	1.769	0.63	1.769	0.427	0.90384367	0.10255659
Infliximab	Epidermolysis bullosa	Skin and subcutaneous tissue disorders congenital NEC	Skin and subcutaneous tissue disorders congenital	Cong	1968-2006	1	80	22501	2983573	0.89	0.206	2.779	1.683	0.277	1.683	0.599	0.30537124	-0.1165338
Infliximab	Epididymitis	Testicular and epididymal infections and inflammations	Male reproductive tract infections and inflammations	Repro	1968-2006	3	314	22499	2983339	1.078	0.419	2.382	1.412	0.348	1.413	0.555	0.23504379	0.07510747
Infliximab	Epiduritis	Central nervous system inflammatory disorders NEC	Central nervous system infections and inflammations	Nerv	1968-2006	2	8	22500	2983645	2.075	0.661	5.356	17.304	27.486	17.311	1.582e-7	1.46997828	0.72996115
Infliximab	Epigastric discomfort	Dyspeptic signs and symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	4	254	22498	2983399	0.811	0.354	1.647	0.898	0.045	0.898	0.831	0.75946954	-0.2094872
Infliximab	Epiglottitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	4	84	22498	2983569	1.841	0.804	3.744	3.129	5.412	3.13	0.02	1.58098772	0.6103089
Infliximab	Epilepsy	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	23	2576	22479	2981077	0.548	0.386	0.759	0.546	8.663	0.545	0.003	0.21854397	-0.60148
Infliximab	Episcleritis	Scleral infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	3	70	22499	2983583	1.489	0.578	3.293	2.475	2.531	2.476	0.112	1.36018652	0.39810475
Infliximab	Epistaxis	Nasal disorders NEC	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	46	10541	22456	2973112	0.481	0.376	0.608	0.475	26.443	0.474	2.714e-7	-0.7877306	-0.731888
Infliximab	Epithelioid sarcoma	Epithelioid sarcomas	Soft tissue sarcomas	Neopl	1968-2006	1	3	22501	2983650	1.306	0.3	4.114	28.221	13.731	28.221	0.0002109	0.946596	0.26696903
Infliximab	Epithelioma	Soft tissue neoplasms benign NEC	Soft tissue neoplasms benign	Neopl	1968-2006	2	18	22500	2983635	1.866	0.602	4.722	9.038	12.751	9.039	0.0003558	1.37284789	0.6237971
Infliximab	Epstein-Barr virus antibody positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	8	154	22494	2983499	2.115	1.167	3.592	2.862	9.1	2.864	0.003	2.01325397	0.74905481
Infliximab	Epstein-Barr virus antigen positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	49	22501	2983604	0.719	0.166	2.243	0.998	0	0.998	0.998	0.53047566	-0.3298939
Infliximab	Epstein-Barr virus infection	Epstein-Barr viral infections	Viral infectious disorders	Infec	1968-2006	18	343	22484	2983310	2.594	1.744	3.743	3.127	24.354	3.131	8.014e-7	2.34853908	0.95320109
Infliximab	Epstein-Barr virus test positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	5	33	22497	2983620	3.562	1.65	7.221	11.291	42.596	11.302	6.731e-11	2.21296353	1.27032218
Infliximab	Erectile dysfunction	Erection and ejaculation conditions and disorders	Sexual function and fertility disorders	Repro	1968-2006	13	10652	22489	2973001	0.274	0.172	0.42	0.267	26.301	0.265	2.921e-7	-2.5454768	-1.2946272
Infliximab	Erosive duodenitis	Duodenal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	2	145	22500	2983508	0.779	0.253	1.954	0.947	0.006	0.947	0.94	0.50342962	-0.2497442
Infliximab	Erosive oesophagitis	Oesophageal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	331	22501	2983322	0.252	0.058	0.788	0.2	3.17	0.2	0.075	-0.8122084	-1.3783262
Infliximab	Eructation	Dyspeptic signs and symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	2	2896	22500	2980757	0.127	0.041	0.319	0.105	15.131	0.105	0.0001003	-2.9314158	-2.0635682
Infliximab	Erysipelas	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	23	371	22479	2983282	3.54	2.492	4.912	4.412	56.433	4.416	5.815e-14	2.59237686	1.26412673
Infliximab	Erythema	Erythemas	Epidermal and dermal conditions	Skin	1968-2006	301	10668	22201	2972985	1.628	1.48	1.789	1.659	76.881	1.669	1.816e-18	1.84551028	0.48735227
Infliximab	Erythema infectiosum	Parvoviral infections	Viral infectious disorders	Infec	1968-2006	2	162	22500	2983491	0.723	0.234	1.812	0.844	0.056	0.844	0.812	0.41856049	-0.3243461
Infliximab	Erythema multiforme	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	19	5932	22483	2977721	0.62	0.421	0.886	0.62	4.345	0.619	0.037	-1.2010047	-0.4780358
Infliximab	Erythema nodosum	Panniculitides	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	30	1239	22472	2982414	3.294	2.424	4.396	3.936	60.015	3.941	9.415e-15	1.55059691	1.19210263
Infliximab	Erythema of eyelid	Lid, lash and lacrimal infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	2	105	22500	2983548	0.763	0.247	1.912	0.915	0.015	0.915	0.902	0.72533136	-0.2704972
Infliximab	Erythrodermic psoriasis	Psoriatic conditions	Epidermal and dermal conditions	Skin	1968-2006	1	32	22501	2983621	0.931	0.215	2.906	1.931	0.444	1.931	0.505	0.67066536	-0.071496
Infliximab	Erythropenia	Red blood cell abnormal findings NEC	Red blood cell disorders	Blood	1968-2006	2	186	22500	2983467	0.832	0.27	2.086	1.051	0.005	1.051	0.945	0.3066543	-0.1839228
Infliximab	Erythrophagocytosis	White blood cell abnormal findings NEC	White blood cell disorders	Blood	1968-2006	1	3	22501	2983650	1.273	0.293	3.999	17.785	9.17	17.785	0.002	0.946596	0.24137632
Infliximab	Erythrosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	17	22501	2983636	1.075	0.249	3.361	3.506	1.616	3.506	0.204	0.80679534	0.07232066
Infliximab	Eschar	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	78	22501	2983575	0.586	0.135	1.829	0.671	0.159	0.671	0.69	0.31888099	-0.5344355
Infliximab	Escherichia bacteraemia	Escherichia infections	Bacterial infectious disorders	Infec	1968-2006	6	105	22496	2983548	2.096	1.058	3.819	3.122	8.23	3.123	0.004	1.92393451	0.74003077
Infliximab	Escherichia infection	Escherichia infections	Bacterial infectious disorders	Infec	1968-2006	68	1132	22434	2982521	3.342	2.728	4.059	3.754	125.014	3.764	5.053e-29	2.7777528	1.20656943
Infliximab	Escherichia sepsis	Escherichia infections	Bacterial infectious disorders	Infec	1968-2006	30	432	22472	2983221	3.823	2.812	5.103	4.796	79.683	4.802	4.395e-19	2.78668005	1.34103545
Infliximab	Escherichia urinary tract infection	Escherichia infections	Bacterial infectious disorders	Infec	1968-2006	29	340	22473	2983313	3.405	2.492	4.566	4.178	62.55	4.184	2.598e-15	2.98435359	1.22524494
Infliximab	Essential hypertension	Vascular hypertensive disorders NEC	Vascular hypertensive disorders	Vasc	1968-2006	10	201	22492	2983452	2.762	1.621	4.465	4.033	20.172	4.035	0.00000708	2.08145797	1.01595505
Infliximab	Essential tremor	Tremor (excl congenital)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	67	22501	2983586	0.71	0.164	2.216	0.972	0.001	0.972	0.978	0.39553403	-0.3424903
Infliximab	Euphoric mood	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	2	2666	22500	2980987	0.121	0.039	0.304	0.099	16.144	0.099	0.00005872	-2.8174759	-2.1119647
Infliximab	Euthyroid sick syndrome	Thyroid disorders NEC	Thyroid gland disorders	Endo	1968-2006	2	16	22500	2983637	1.874	0.604	4.746	10.06	13.112	10.06	0.0002934	1.3917579	0.62807518
Infliximab	Ewings sarcoma	Bone sarcomas	Skeletal neoplasms malignant and unspecified	Neopl	1968-2006	3	15	22499	2983638	2.514	0.966	5.683	12.293	24.147	12.294	8.928e-7	1.80679546	0.92187511
Infliximab	Excitability				1968-2006	2	618	22500	2983035	0.241	0.078	0.603	0.214	5.867	0.213	0.015	-0.9220983	-1.4229583
Infliximab	Excoriation	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	11	794	22491	2982859	0.794	0.478	1.257	0.818	0.428	0.818	0.513	0.76110268	-0.2306718
Infliximab	Exercise electrocardiogram abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	38	22500	2983615	1.548	0.501	3.888	4.158	4.362	4.158	0.037	1.19624438	0.43696378
Infliximab	Exercise test abnormal	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	107	22501	2983546	0.704	0.163	2.196	0.954	0.002	0.954	0.963	0.13438423	-0.3509769
Infliximab	Exercise tolerance decreased	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	238	22500	2983415	0.454	0.147	1.138	0.446	1.349	0.446	0.245	0.09039916	-0.7896581
Infliximab	Exfoliative rash	Exfoliative conditions	Epidermal and dermal conditions	Skin	1968-2006	11	476	22491	2983177	1.477	0.889	2.338	1.673	2.868	1.673	0.09	1.35810664	0.390013
Infliximab	Exophthalmos	Structural change, deposit and degeneration of eye NEC	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	3	321	22499	2983332	0.766	0.298	1.694	0.865	0.063	0.865	0.802	0.21280044	-0.2665731
Infliximab	Exostosis	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	10	597	22492	2983056	1.034	0.607	1.67	1.108	0.103	1.108	0.748	0.97748485	0.03343478
Infliximab	Explorative laparotomy	Abdominal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	2	4	22500	2983649	2.215	0.691	5.924	38.559	45.871	38.571	1.263e-11	1.51073838	0.7952524
Infliximab	Exposure to communicable disease	Non-occupational and unspecified environmental problems	Environmental issues	SocCi	1968-2006	1	11	22501	2983642	1.072	0.248	3.35	3.534	1.59	3.534	0.207	0.86505951	0.06952606
Infliximab	Exposure to toxic agent	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	1	43	22501	2983610	0.832	0.192	2.597	1.415	0.115	1.415	0.734	0.5784143	-0.1839228
Infliximab	Expressive language disorder	Communications disorders	Communication disorders and disturbances	Psych	1968-2006	1	77	22501	2983576	0.697	0.161	2.174	0.933	0.005	0.933	0.946	0.3256836	-0.3609699
Infliximab	Extensor plantar response	Abnormal reflexes	Neurological disorders NEC	Nerv	1968-2006	4	426	22498	2983227	0.795	0.347	1.616	0.877	0.068	0.877	0.794	0.23409031	-0.2294132
Infliximab	Extradural abscess	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	7	108	22495	2983545	2.656	1.407	4.662	4.317	16.568	4.319	0.00004694	2.09317556	0.97682123
Infliximab	Extradural haematoma	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	1	273	22501	2983380	0.324	0.075	1.013	0.279	1.887	0.279	0.17	-0.6202412	-1.1270118
Infliximab	Extranodal marginal zone B-cell lymphoma (MALT type)	Extranodal marginal zone B-cell lymphomas (low grade B-cell)	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	6	18	22496	2983635	5.001	2.242	15.057	20.942	77.94	20.95	1.062e-18	2.55814824	1.60963789
Infliximab	Extrapyramidal disorder	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	6726	22501	2976927	0.054	0.012	0.169	0.037	25.417	0.037	4.617e-7	-4.6964898	-2.9187712
Infliximab	Extrasystoles	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	7	1954	22495	2981699	0.417	0.221	0.731	0.41	5.894	0.41	0.015	-0.9825169	-0.8746691
Infliximab	Extravasation	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	9	709	22493	2982944	0.816	0.466	1.349	0.852	0.227	0.852	0.634	0.63844472	-0.2033409
Infliximab	Extravasation blood	Haemorrhages NEC	Vascular haemorrhagic disorders	Vasc	1968-2006	2	23	22500	2983630	1.731	0.56	4.359	6.288	8.025	6.288	0.005	1.32662952	0.54869928
Infliximab	Extremity contracture	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	21	22501	2983632	0.993	0.23	3.102	2.479	0.817	2.479	0.366	0.76921993	-0.0070246
Infliximab	Extremity necrosis	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	4	104	22498	2983549	1.434	0.626	2.914	2.025	1.952	2.025	0.162	1.45631298	0.36046774
Infliximab	Eye allergy	Ocular infections, inflammations and associated manifestations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	31	22501	2983622	0.931	0.215	2.907	1.954	0.448	1.954	0.503	0.67935182	-0.071496
Infliximab	Eye degenerative disorder	Structural change, deposit and degeneration of eye NEC	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	12	22501	2983641	1.16	0.268	3.63	5.373	3.193	5.373	0.074	0.85518395	0.14842001
Infliximab	Eye disorder	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	30	5757	22472	2977896	0.678	0.499	0.904	0.677	4.503	0.677	0.034	-0.5292327	-0.388608
Infliximab	Eye haemorrhage	Ocular bleeding and vascular disorders NEC	Ocular haemorrhages and vascular disorders NEC	Eye	1968-2006	11	2385	22491	2981268	0.45	0.271	0.713	0.443	7.554	0.442	0.006	-0.6699981	-0.7985077
Infliximab	Eye infection	Eye and eyelid infections	Infections - pathogen class unspecified	Infec	1968-2006	8	419	22494	2983234	1.226	0.677	2.081	1.386	0.834	1.386	0.361	1.08979008	0.20375684
Infliximab	Eye infection fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	37	22501	2983616	0.879	0.203	2.744	1.626	0.242	1.626	0.623	0.62800058	-0.1289704
Infliximab	Eye infection staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	53	22501	2983600	0.792	0.183	2.472	1.25	0.047	1.25	0.828	0.49937916	-0.2331939
Infliximab	Eye infection toxoplasmal	Toxoplasma infections	Protozoal infectious disorders	Infec	1968-2006	5	9	22497	2983644	4.394	1.88	13.94	27.421	69.632	27.436	7.148e-17	2.43033823	1.48023997
Infliximab	Eye inflammation	Ocular infections, inflammations and associated manifestations	Ocular infections, irritations and inflammations	Eye	1968-2006	4	350	22498	2983303	0.697	0.304	1.415	0.744	0.35	0.744	0.554	0.4431024	-0.3609699
Infliximab	Eye injury	Eye injuries NEC	Injuries NEC	Inj&P	1968-2006	1	171	22501	2983482	0.393	0.091	1.228	0.358	1.133	0.358	0.287	-0.2046768	-0.9339457
Infliximab	Eye irritation	Ocular infections, inflammations and associated manifestations	Ocular infections, irritations and inflammations	Eye	1968-2006	10	2089	22492	2981564	0.369	0.217	0.596	0.36	11.29	0.36	0.001	-0.6152009	-0.9969586
Infliximab	Eye movement disorder	Ocular nerve and muscle disorders	Ocular neuromuscular disorders	Eye	1968-2006	2	865	22500	2982788	0.181	0.059	0.455	0.155	9.231	0.155	0.002	-1.3312145	-1.7092582
Infliximab	Eye oedema	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	4	177	22498	2983476	0.958	0.418	1.946	1.118	0.048	1.118	0.826	1.07537305	-0.0429075
Infliximab	Eye operation	Eye therapeutic procedures NEC	Eye therapeutic procedures	Surg	1968-2006	4	113	22498	2983540	1.664	0.726	3.383	2.595	3.693	2.596	0.055	1.40354167	0.50922434
Infliximab	Eye pain	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	18	11120	22484	2972533	0.378	0.254	0.545	0.371	19.071	0.37	0.00001259	-2.1669794	-0.9728611
Infliximab	Eye pruritus	Ocular infections, inflammations and associated manifestations	Ocular infections, irritations and inflammations	Eye	1968-2006	4	553	22498	2983100	0.373	0.163	0.757	0.359	4.538	0.359	0.033	-0.059152	-0.9861769
Infliximab	Eye rolling	Ocular sensation disorders	Ocular sensory symptoms NEC	Eye	1968-2006	3	622	22499	2983031	0.346	0.135	0.766	0.327	4.095	0.327	0.043	-0.5166033	-1.0613165
Infliximab	Eye swelling	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	15	1528	22487	2982125	0.478	0.309	0.712	0.472	8.75	0.471	0.003	0.33882588	-0.7381445
Infliximab	Eyelid disorder	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	1	357	22501	2983296	0.249	0.057	0.778	0.195	3.247	0.195	0.072	-0.8906156	-1.3903024
Infliximab	Eyelid infection	Eye and eyelid infections	Infections - pathogen class unspecified	Infec	1968-2006	1	16	22501	2983637	1.072	0.248	3.35	3.364	1.584	3.364	0.208	0.81634411	0.06952606
Infliximab	Eyelid oedema	Lid, lash and lacrimal infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	27	2421	22475	2981232	0.885	0.641	1.198	0.9	0.298	0.899	0.585	0.52302023	-0.1221676
Infliximab	Eyelid ptosis	Eyelid movement disorders	Ocular neuromuscular disorders	Eye	1968-2006	8	1232	22494	2982421	0.75	0.414	1.273	0.778	0.496	0.778	0.481	-0.2035282	-0.2876821
Infliximab	Face injury	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	3	217	22499	2983436	0.675	0.262	1.492	0.728	0.294	0.728	0.588	0.58482384	-0.3930426
Infliximab	Face oedema	Oedema NEC	General system disorders NEC	Genrl	1968-2006	115	28246	22387	2955407	1.031	0.882	1.198	1.037	0.154	1.038	0.695	-0.9032587	0.03052921
Infliximab	Facial bones fracture	Skull fractures, facial bone fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	4	302	22498	2983351	0.773	0.338	1.571	0.845	0.11	0.845	0.741	0.59263385	-0.2574762
Infliximab	Facial neuralgia	Trigeminal disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	26	22501	2983627	0.999	0.231	3.119	2.5	0.854	2.5	0.356	0.72358631	-0.0010005
Infliximab	Facial pain	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	6	609	22496	2983044	0.607	0.306	1.105	0.618	1.385	0.618	0.239	0.3099021	-0.4992265
Infliximab	Facial palsy	Facial cranial nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	45	3052	22457	2980601	1.431	1.115	1.814	1.482	6.847	1.483	0.009	0.91538446	0.3583735
Infliximab	Facial paresis	Facial cranial nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	4	268	22498	2983385	0.703	0.307	1.427	0.752	0.326	0.751	0.568	0.7087853	-0.3523984
Infliximab	Facial spasm	Facial cranial nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	47	22501	2983606	0.779	0.18	2.431	1.2	0.031	1.2	0.859	0.54627889	-0.2497442
Infliximab	Factor II mutation	Coagulation disorders congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	1	2	22501	2983651	1.365	0.312	4.334	50.63	38.755	50.63	4.806e-10	0.95711984	0.31115443
Infliximab	Factor V deficiency	Coagulation disorders congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	1	25	22501	2983628	0.984	0.228	3.073	2.355	0.752	2.355	0.386	0.7325983	-0.0161294
Infliximab	Faecal incontinence	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	16	2237	22486	2981416	0.692	0.454	1.019	0.7	2.045	0.7	0.153	-0.0834737	-0.3681693
Infliximab	Faecal volume decreased	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	18	22501	2983635	1.069	0.247	3.34	3.4	1.533	3.4	0.216	0.79730935	0.06672363
Infliximab	Faecal vomiting	Nausea and vomiting symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	8	22501	2983645	1.21	0.279	3.791	8.466	4.887	8.466	0.027	0.89509832	0.19062036
Infliximab	Faecaloma	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	6	923	22496	2982730	0.518	0.261	0.943	0.518	2.649	0.518	0.104	-0.195584	-0.65778
Infliximab	Faeces discoloured	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	13	3159	22489	2980494	0.337	0.211	0.516	0.33	17.722	0.329	0.00002557	-0.8339838	-1.0876723
Infliximab	Faeces hard	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	222	22501	2983431	0.368	0.085	1.15	0.326	1.366	0.326	0.243	-0.4273668	-0.9996723
Infliximab	Faeces pale	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	351	22501	2983302	0.289	0.067	0.902	0.24	2.425	0.24	0.119	-0.872896	-1.2413286
Infliximab	Failure of implant	Device malfunction events	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	238	22501	2983415	0.349	0.081	1.089	0.301	1.579	0.301	0.209	-0.4906963	-1.0526834
Infliximab	Failure to anastomose	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	21	22501	2983632	1.096	0.253	3.426	3.688	1.902	3.689	0.168	0.76921993	0.09166719
Infliximab	Failure to thrive	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	5	533	22497	2983120	0.583	0.277	1.114	0.596	1.355	0.596	0.244	0.24414035	-0.5395681
Infliximab	Fall	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	264	21683	22238	2961970	0.771	0.696	0.852	0.767	18.622	0.764	0.00001594	0.65971779	-0.2600669
Infliximab	Fallopian tube cancer	Fallopian tube neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	3	10	22499	2983643	3.066	1.108	8.72	28.114	57.065	28.123	4.216e-14	1.85518405	1.12037378
Infliximab	Fallopian tube cancer stage III	Fallopian tube neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.344	0.308	4.254	1075.473	51.196	1083.041	8.358e-13	0.97840063	0.29565024
Infliximab	Fallopian tube cyst	Ovarian and fallopian tube cysts and neoplasms	Ovarian and fallopian tube disorders	Repro	1968-2006	3	18	22499	2983635	2.367	0.914	5.298	9.874	18.102	9.877	0.00002094	1.77852258	0.86162333
Infliximab	Fallots tetralogy	Multiple cardiac abnormalities congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	107	22501	2983546	0.595	0.138	1.856	0.693	0.138	0.693	0.71	0.13438423	-0.5191939
Infliximab	False positive laboratory result	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	2	95	22500	2983558	0.888	0.288	2.225	1.172	0.048	1.172	0.827	0.78658155	-0.1187835
Infliximab	False positive tuberculosis test	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	9	22501	2983644	1.195	0.276	3.742	6.364	4.254	6.364	0.039	0.88501574	0.17814619
Infliximab	Family stress	Family and partner issues	Family issues	SocCi	1968-2006	1	216	22501	2983437	0.302	0.07	0.944	0.253	2.207	0.253	0.137	-0.4028829	-1.1973283
Infliximab	Fasciitis	Muscle infections and inflammations	Muscle disorders	Musc	1968-2006	9	125	22493	2983528	2.922	1.667	4.838	4.529	22.376	4.53	2.241e-6	2.30884128	1.07226831
Infliximab	Fat necrosis	Necrosis NEC	Tissue disorders NEC	Genrl	1968-2006	1	87	22501	2983566	0.573	0.133	1.789	0.642	0.192	0.642	0.661	0.25905904	-0.5568696
Infliximab	Fatigue	Asthenic conditions	General system disorders NEC	Genrl	1968-2006	424	39635	22078	2944018	0.716	0.66	0.775	0.711	50.293	0.706	1.324e-12	0.46826716	-0.3340751
Infliximab	Fatty acid deficiency	Lipid metabolism and deposit disorders NEC	Lipid metabolism disorders	Metab	1968-2006	2	4	22500	2983649	2.295	0.704	6.383	40.114	59.458	40.114	1.249e-14	1.51073838	0.83073284
Infliximab	Fear	Fear symptoms	Anxiety disorders and symptoms	Psych	1968-2006	6	2459	22496	2981194	0.169	0.086	0.309	0.159	26.861	0.159	2.187e-7	-1.4864668	-1.7778566
Infliximab	Fear of falling	Fear symptoms	Anxiety disorders and symptoms	Psych	1968-2006	1	22	22501	2983631	1.004	0.232	3.136	2.621	0.9	2.621	0.343	0.75997701	0.00399202
Infliximab	Febrile convulsion	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	1	192	22501	2983461	0.368	0.085	1.149	0.33	1.369	0.33	0.242	-0.3005686	-0.9996723
Infliximab	Febrile infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	51	22501	2983602	0.777	0.18	2.424	1.186	0.029	1.186	0.864	0.51484364	-0.2523149
Infliximab	Febrile neutropenia	Neutropenias	White blood cell disorders	Blood	1968-2006	13	3857	22489	2979796	0.174	0.109	0.266	0.167	54.218	0.166	1.794e-13	-1.1107077	-1.7487
Infliximab	Feeding disorder	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	5	306	22497	2983347	0.861	0.408	1.645	0.946	0.015	0.946	0.903	0.83934944	-0.1496608
Infliximab	Feeding disorder neonatal	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	2	484	22500	2983169	0.283	0.092	0.71	0.252	4.365	0.252	0.037	-0.6395697	-1.2623084
Infliximab	Feeding tube complication	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	61	22501	2983592	0.665	0.154	2.075	0.848	0.026	0.848	0.872	0.43912725	-0.4079682
Infliximab	Feeling abnormal	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	113	15997	22389	2967656	0.401	0.342	0.466	0.395	105.694	0.391	8.604e-25	-0.1115655	-0.9137939
Infliximab	Feeling cold	Body temperature perception	Body temperature conditions	Genrl	1968-2006	45	2393	22457	2981260	1.177	0.917	1.493	1.205	1.524	1.205	0.217	1.2448396	0.16296883
Infliximab	Feeling drunk	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	728	22500	2982925	0.202	0.065	0.507	0.175	7.819	0.175	0.005	-1.1187169	-1.5994876
Infliximab	Feeling hot	Body temperature perception	Body temperature conditions	Genrl	1968-2006	99	3980	22403	2979673	1.558	1.318	1.832	1.6	21.556	1.603	3.437e-6	1.65231953	0.44340295
Infliximab	Feeling hot and cold	Body temperature perception	Body temperature conditions	Genrl	1968-2006	5	445	22497	2983208	0.623	0.295	1.189	0.641	0.983	0.641	0.321	0.44680674	-0.4732088
Infliximab	Feeling jittery	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	5	2850	22497	2980803	0.146	0.069	0.279	0.136	27.854	0.136	1.308e-7	-1.9107839	-1.9241487
Infliximab	Feeling of body temperature change	Body temperature perception	Body temperature conditions	Genrl	1968-2006	4	112	22498	2983541	1.486	0.649	3.02	2.147	2.304	2.147	0.129	1.40931074	0.39608795
Infliximab	Feltys syndrome	Rheumatoid arthropathies	Joint disorders	Musc	1968-2006	11	29	22491	2983624	9.019	4.187	19.589	21.267	143.814	21.277	3.902e-33	3.1962454	2.19933346
Infliximab	Female genital tract fistula	Reproductive tract disorders NEC (excl neoplasms)	Reproductive tract disorders NEC	Repro	1968-2006	16	58	22486	2983595	6.892	4.228	12.011	13.678	139.448	13.694	3.515e-32	3.4406848	1.93036132
Infliximab	Femoral arterial stenosis	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	79	22501	2983574	0.699	0.162	2.182	0.941	0.004	0.941	0.952	0.31211031	-0.3581045
Infliximab	Femoral artery occlusion	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	86	22501	2983567	0.564	0.13	1.761	0.629	0.217	0.628	0.641	0.26558476	-0.572701
Infliximab	Femoral hernia	Femoral hernias	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	2	10	22500	2983643	1.846	0.596	4.666	9.637	11.975	9.637	0.001	1.45002205	0.61302114
Infliximab	Femoral neck fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	18	345	22484	2983308	2.539	1.707	3.664	3.102	23.247	3.105	1.425e-6	2.34271604	0.9317703
Infliximab	Femoral nerve lesion	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	1	2	22501	2983651	1.343	0.308	4.251	66.861	24.796	66.861	6.373e-7	0.95711984	0.29490592
Infliximab	Femur fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	30	845	22472	2982808	2.155	1.585	2.874	2.382	22.597	2.385	1.997e-6	2.02653839	0.76779072
Infliximab	Fibrin D dimer increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	10	516	22492	2983137	1.106	0.65	1.786	1.198	0.32	1.198	0.572	1.14462822	0.1007499
Infliximab	Fibrin degradation products increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	216	22500	2983437	0.672	0.218	1.684	0.757	0.151	0.757	0.697	0.17797032	-0.3974969
Infliximab	Fibrinolysis increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	57	22501	2983596	1.167	0.27	3.654	5.247	3.389	5.247	0.066	0.46893872	0.15443635
Infliximab	Fibroadenoma of breast	Breast and nipple neoplasms benign	Breast neoplasms benign (incl nipple)	Neopl	1968-2006	2	80	22500	2983573	1.073	0.348	2.69	1.653	0.494	1.653	0.482	0.8836262	0.07045846
Infliximab	Fibrocystic breast disease	Benign and malignant breast neoplasms	Breast disorders	Repro	1968-2006	5	788	22497	2982865	1.272	0.603	2.429	1.583	1.012	1.583	0.314	-0.2203301	0.24059046
Infliximab	Fibroma	Neoplasms benign site unspecified NEC	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	3	97	22499	2983556	1.241	0.482	2.744	1.797	0.988	1.797	0.32	1.18296967	0.21591751
Infliximab	Fibromyalgia	Muscle pains	Muscle disorders	Musc	1968-2006	11	1083	22491	2982570	0.588	0.354	0.931	0.591	3.085	0.591	0.079	0.37370315	-0.5310283
Infliximab	Fibrosarcoma	Fibrosarcomas malignant	Soft tissue sarcomas	Neopl	1968-2006	1	14	22501	2983639	1.153	0.266	3.608	5.367	3.014	5.367	0.083	0.83563334	0.14236724
Infliximab	Fibrosis	Fibrosis NEC	Tissue disorders NEC	Genrl	1968-2006	21	631	22481	2983022	2.123	1.471	2.987	2.408	16.307	2.409	0.00005387	1.89236664	0.75283018
Infliximab	Fibula fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	2	147	22500	2983506	0.693	0.225	1.737	0.795	0.106	0.794	0.745	0.49318202	-0.3667253
Infliximab	Filariasis	Nematode infections	Helminthic disorders	Infec	1968-2006	1	67	22501	2983586	0.591	0.137	1.846	0.685	0.146	0.685	0.702	0.39553403	-0.5259393
Infliximab	Finger amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	2	137	22500	2983516	0.744	0.241	1.865	0.882	0.031	0.882	0.86	0.54516365	-0.2957142
Infliximab	Finger repair operation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.363	0.311	4.326	2954.316	37.669	2954.316	8.384e-10	0.967721	0.30968815
Infliximab	Fistula	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	107	579	22395	2983074	9.67	8.103	11.475	12.712	899.348	12.763	0	4.12671559	2.26902831
Infliximab	Fistula repair	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	4	22	22498	2983631	3.128	1.338	6.665	15.023	36.058	15.023	1.915e-9	2.05452664	1.14039382
Infliximab	Flank pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	14	569	22488	2983084	1.401	0.893	2.114	1.537	2.509	1.537	0.113	1.4724838	0.33718627
Infliximab	Flat affect	Affect alterations NEC	Mood disorders and disturbances NEC	Psych	1968-2006	2	463	22500	2983190	0.299	0.097	0.749	0.27	3.921	0.27	0.048	-0.5898143	-1.2073117
Infliximab	Flatulence	Flatulence, bloating and distension	Gastrointestinal signs and symptoms	Gastr	1968-2006	28	13418	22474	2970235	0.359	0.261	0.483	0.352	33.226	0.351	8.206e-9	-1.8267905	-1.0244329
Infliximab	Flavivirus infection	Flaviviral infections	Viral infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.378	0.314	4.385	1089.712	93.672	1097.429	3.723e-22	0.97840063	0.32063317
Infliximab	Flavobacterium infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.292	0.298	4.067	25.104	11.583	25.104	0.001	0.95711984	0.25619141
Infliximab	Flight of ideas	Thinking disturbances	Disturbances in thinking and perception	Psych	1968-2006	1	127	22501	2983526	0.496	0.115	1.547	0.509	0.473	0.509	0.492	0.0196303	-0.7011794
Infliximab	Floppy infant	Muscle tone abnormalities	Muscle disorders	Musc	1968-2006	1	20	22501	2983633	0.964	0.223	3.012	2.245	0.628	2.245	0.428	0.77852244	-0.036664
Infliximab	Fluid intake reduced	Fluid intake decreased	Electrolyte and fluid balance conditions	Metab	1968-2006	2	327	22500	2983326	0.392	0.127	0.982	0.374	2.089	0.374	0.148	-0.2179182	-0.9364934
Infliximab	Fluid overload	Total fluid volume increased	Electrolyte and fluid balance conditions	Metab	1968-2006	13	1159	22489	2982494	0.751	0.471	1.149	0.766	0.906	0.765	0.341	0.50718599	-0.2863496
Infliximab	Fluid retention	Total fluid volume increased	Electrolyte and fluid balance conditions	Metab	1968-2006	20	3687	22482	2979966	0.351	0.241	0.498	0.344	24.873	0.343	6.124e-7	-0.4656968	-1.0469691
Infliximab	Flushing	Peripheral vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	580	8752	21922	2974901	4.751	4.436	5.085	5.201	1793.426	5.335	0	3.02055898	1.55835512
Infliximab	Focal glomerulosclerosis	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	2	149	22500	2983504	0.641	0.208	1.606	0.71	0.236	0.71	0.627	0.48300669	-0.4447258
Infliximab	Focal nodular hyperplasia	Hepatobiliary neoplasms benign	Hepatic and biliary neoplasms benign	Neopl	1968-2006	1	80	22501	2983573	0.55	0.127	1.717	0.605	0.26	0.605	0.61	0.30537124	-0.597837
Infliximab	Foetal cardiac disorder	Foetal complications NEC	Foetal complications	Preg	1968-2006	1	72	22501	2983581	0.555	0.128	1.732	0.611	0.246	0.611	0.62	0.36018617	-0.5887872
Infliximab	Foetal disorder	Foetal complications NEC	Foetal complications	Preg	1968-2006	4	1128	22498	2982525	0.42	0.183	0.853	0.412	3.355	0.412	0.067	-0.9333338	-0.8675006
Infliximab	Foetal growth retardation	Foetal growth complications	Foetal complications	Preg	1968-2006	7	773	22495	2982880	0.547	0.29	0.958	0.549	2.554	0.549	0.11	0.21509861	-0.6033065
Infliximab	Foetal heart rate abnormal	Foetal and neonatal diagnostic procedures	Foetal and neonatal investigations	Inv	1968-2006	1	118	22501	2983535	0.387	0.089	1.209	0.35	1.194	0.35	0.275	0.07014349	-0.9493306
Infliximab	Foetal malformation	Congenital disorders NEC	Congenital and hereditary disorders NEC	Cong	1968-2006	1	61	22501	2983592	0.68	0.157	2.121	0.887	0.014	0.887	0.906	0.43912725	-0.3856625
Infliximab	Follicle centre lymphoma, follicular grade I, II, III	Follicle centre lymphomas, follicular grade I, II, III	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	10	22501	2983643	1.203	0.278	3.77	8.003	4.596	8.003	0.032	0.87500312	0.18481844
Infliximab	Follicle centre lymphoma, follicular grade I, II, III stage III	Follicle centre lymphomas, follicular grade I, II, III	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	2	22501	2983651	1.33	0.305	4.201	26.518	19.907	26.518	8.131e-6	0.95711984	0.28517894
Infliximab	Follicular thyroid cancer	Thyroid neoplasms malignant	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	12	22501	2983641	1.172	0.271	3.667	5.638	3.505	5.638	0.061	0.85518395	0.15871169
Infliximab	Folliculitis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	22	313	22480	2983340	3.93	2.743	5.494	5.203	66.643	5.208	3.254e-16	2.70209342	1.36863943
Infliximab	Food allergy	Allergies to foods, food additives, drugs and other chemicals	Allergic conditions	Immun	1968-2006	2	291	22500	2983362	0.455	0.147	1.141	0.451	1.338	0.451	0.247	-0.1010182	-0.7874579
Infliximab	Food intolerance	Food malabsorption and intolerance syndromes (excl sugar intolerance)	Food intolerance syndromes	Metab	1968-2006	4	201	22498	2983452	0.977	0.427	1.986	1.15	0.074	1.15	0.785	0.96929663	-0.0232686
Infliximab	Food poisoning	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	9	232	22493	2983421	1.902	1.085	3.143	2.404	6.878	2.405	0.009	1.82350997	0.64290596
Infliximab	Foot amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	4	162	22498	2983491	1.15	0.502	2.336	1.443	0.519	1.443	0.471	1.14586241	0.13976194
Infliximab	Foot deformity	Extremity deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	2	67	22500	2983586	1.04	0.337	2.608	1.563	0.383	1.563	0.536	0.97335751	0.03922071
Infliximab	Foot fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	14	762	22488	2982891	1.02	0.65	1.54	1.071	0.063	1.071	0.801	1.12832446	0.01980263
Infliximab	Foot operation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	17	128	22485	2983525	4.225	2.803	6.182	6.549	65.755	6.556	5.107e-16	3.09871681	1.44101926
Infliximab	Foreign body aspiration	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	1	190	22501	2983463	0.376	0.087	1.175	0.334	1.29	0.334	0.256	-0.2917057	-0.9781661
Infliximab	Foreign body trauma	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	4	584	22498	2983069	0.434	0.189	0.881	0.428	3.069	0.427	0.08	-0.1225164	-0.8347107
Infliximab	Formication	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	4	592	22498	2983061	0.408	0.178	0.829	0.398	3.621	0.398	0.057	-0.1384268	-0.8964881
Infliximab	Fracture	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	8	742	22494	2982911	0.676	0.373	1.148	0.692	1.067	0.692	0.302	0.433208	-0.3915622
Infliximab	Fracture malunion	Pathological fractures and complications	Fractures	Musc	1968-2006	2	10	22500	2983643	1.853	0.598	4.687	10.185	12.247	10.185	0.000466	1.45002205	0.61680595
Infliximab	Fracture nonunion	Pathological fractures and complications	Fractures	Musc	1968-2006	1	56	22501	2983597	0.701	0.162	2.187	0.945	0.003	0.945	0.956	0.47648884	-0.3552474
Infliximab	Fractured sacrum	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	1	56	22501	2983597	0.656	0.152	2.046	0.824	0.036	0.824	0.85	0.47648884	-0.4215945
Infliximab	Frequent bowel movements	Gastrointestinal spastic and hypermotility disorders	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	15	1111	22487	2982542	0.985	0.638	1.468	1.027	0.01	1.027	0.919	0.75160166	-0.0151136
Infliximab	Fuchs syndrome	Anterior chamber structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	3	22501	2983650	1.304	0.3	4.108	33.426	13.486	33.426	0.0002404	0.946596	0.26543646
Infliximab	Full blood count abnormal	Blood counts NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	2	174	22500	2983479	0.69	0.224	1.729	0.787	0.112	0.787	0.737	0.36152286	-0.3710637
Infliximab	Full blood count decreased	Blood counts NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	3	253	22499	2983400	0.701	0.272	1.549	0.767	0.208	0.767	0.648	0.44492927	-0.3552474
Infliximab	Functional residual capacity decreased	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	6	22501	2983647	1.266	0.292	3.977	12.612	8.437	12.612	0.004	0.91547736	0.23586232
Infliximab	Fungaemia	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	21	165	22481	2983488	5.356	3.683	7.654	8.35	112.724	8.359	2.48e-26	3.19012989	1.67821743
Infliximab	Fungal infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	83	2830	22419	2980823	2.236	1.862	2.668	2.36	61.959	2.365	3.507e-15	1.86884869	0.80468856
Infliximab	Fungal oesophagitis	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	3	29	22499	2983624	2.07	0.803	4.596	5.677	10.083	5.678	0.001	1.67935201	0.72754861
Infliximab	Fungal rash	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	2	63	22500	2983590	1.257	0.407	3.152	2.316	1.419	2.316	0.234	1.00212868	0.22872793
Infliximab	Fungal sepsis	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	9	77	22493	2983576	3.779	2.147	6.311	7.165	41.171	7.168	1.395e-10	2.59406975	1.32945942
Infliximab	Fungal skin infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	7	401	22495	2983252	1.916	1.016	3.358	2.576	6.396	2.577	0.011	0.96961831	0.65023968
Infliximab	Fungus serology test positive	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	30	22500	2983623	1.594	0.516	4.007	4.877	5.101	4.877	0.024	1.26431441	0.46624658
Infliximab	Fungus sputum test positive	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	3	21	22499	2983632	2.298	0.889	5.129	8.183	15.826	8.184	0.00006944	1.75079308	0.83203918
Infliximab	Fungus stool identified	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	15	22500	2983638	1.761	0.569	4.439	7.059	8.902	7.061	0.003	1.40130667	0.56588183
Infliximab	Fungus urine test positive	Fungus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	25	22501	2983628	1.002	0.232	3.128	2.479	0.878	2.479	0.349	0.7325983	0.001998
Infliximab	Furuncle	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	14	663	22488	2982990	1.959	1.249	2.957	2.286	9.662	2.287	0.002	1.29461523	0.67243414
Infliximab	Gait disturbance	Gait disturbances	General system disorders NEC	Genrl	1968-2006	52	11034	22450	2972619	0.556	0.441	0.694	0.551	18.839	0.55	0.00001422	-0.6802739	-0.586987
Infliximab	Gallbladder cancer	Gallbladder neoplasms malignant	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	8	102	22494	2983551	2.838	1.565	4.828	4.526	20.214	4.529	6.925e-6	2.29241589	1.04309958
Infliximab	Gallbladder cancer stage 0	Gallbladder neoplasms malignant	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.343	0.308	4.249	1074.85	50.194	1082.447	1.393e-12	0.97840063	0.29490592
Infliximab	Gallbladder disorder	Gallbladder disorders NEC	Gallbladder disorders	Hepat	1968-2006	28	2011	22474	2981642	1.019	0.742	1.372	1.044	0.05	1.044	0.823	0.82268795	0.01882175
Infliximab	Gallbladder oedema	Gallbladder disorders NEC	Gallbladder disorders	Hepat	1968-2006	1	63	22501	2983590	0.746	0.173	2.329	1.084	0.006	1.084	0.937	0.42444935	-0.2930297
Infliximab	Gallbladder operation	Biliary tract and gallbladder therapeutic procedures	Hepatobiliary therapeutic procedures	Surg	1968-2006	12	217	22490	2983436	2.378	1.462	3.699	3.045	15.237	3.046	0.00009482	2.24900085	0.8662598
Infliximab	Gallbladder perforation	Gallbladder disorders NEC	Gallbladder disorders	Hepat	1968-2006	3	59	22499	2983594	1.745	0.677	3.861	3.437	4.975	3.438	0.026	1.43912756	0.55675456
Infliximab	Gallop rhythm present	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	149	22499	2983504	1.086	0.422	2.401	1.434	0.376	1.434	0.54	0.89298356	0.08250122
Infliximab	Gamma-glutamyltransferase	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	80	22501	2983573	0.568	0.131	1.772	0.635	0.208	0.635	0.649	0.30537124	-0.5656339
Infliximab	Gamma-glutamyltransferase abnormal	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	100	22501	2983553	0.506	0.117	1.581	0.522	0.426	0.522	0.514	0.1768059	-0.6812186
Infliximab	Gamma-glutamyltransferase increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	63	8906	22439	2974747	0.657	0.532	0.803	0.653	11.435	0.652	0.001	-0.1054913	-0.4200713
Infliximab	Gammopathy	Plasma cell neoplasms NEC	Plasma cell neoplasms	Neopl	1968-2006	10	65	22492	2983588	4.785	2.752	8.178	10.311	69.152	10.32	9.118e-17	2.80571919	1.56548602
Infliximab	Ganglion				1968-2006	8	63	22494	2983590	3.982	2.176	6.923	8.903	46.415	8.905	9.57e-12	2.54414777	1.38178421
Infliximab	Ganglioneuroma	Neuromas	Nervous system neoplasms benign	Neopl	1968-2006	1	10	22501	2983643	1.171	0.27	3.664	5.713	3.477	5.713	0.062	0.87500312	0.15785808
Infliximab	Gangrene	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	15	1335	22487	2982318	1.217	0.788	1.813	1.299	1.003	1.299	0.317	0.51535607	0.19638881
Infliximab	Gastrectomy	Gastric therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	38	22501	2983615	0.946	0.219	2.953	2.03	0.518	2.03	0.472	0.61961696	-0.0555127
Infliximab	Gastric bypass	Gastric therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	4	177	22498	2983476	0.902	0.394	1.833	1.032	0.004	1.032	0.951	1.07537305	-0.1031408
Infliximab	Gastric cancer	Gastric neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	24	615	22478	2983038	2.376	1.686	3.274	2.712	24.384	2.715	7.892e-7	2.10087207	0.8654184
Infliximab	Gastric cancer stage IV	Gastric neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	28	22500	2983625	1.662	0.538	4.182	5.316	6.399	5.316	0.011	1.28184581	0.5080217
Infliximab	Gastric dilatation	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	1	143	22501	2983510	0.581	0.134	1.813	0.658	0.172	0.658	0.679	-0.066024	-0.5430045
Infliximab	Gastric disorder	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	7	1664	22495	2981989	0.268	0.142	0.469	0.255	15.086	0.255	0.0001027	-0.7673804	-1.3167683
Infliximab	Gastric haemorrhage	Gastric and oesophageal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	8	1136	22494	2982517	0.466	0.257	0.79	0.462	4.994	0.462	0.025	-0.0989557	-0.7635696
Infliximab	Gastric mucosal hypertrophy	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	1	23	22501	2983630	1.005	0.232	3.139	2.559	0.905	2.559	0.341	0.75079293	0.00498754
Infliximab	Gastric mucosal lesion	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	2	111	22500	2983542	1.056	0.342	2.648	1.603	0.432	1.603	0.511	0.68979161	0.05448819
Infliximab	Gastric neoplasm	Gastrointestinal neoplasms malignancy unspecified NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	47	22500	2983606	1.193	0.387	2.991	2.09	1.04	2.09	0.308	1.12331827	0.17647114
Infliximab	Gastric operation	Gastric therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	2	36	22500	2983617	1.302	0.422	3.267	2.567	1.749	2.568	0.186	1.2129632	0.26390154
Infliximab	Gastric perforation	Gastric ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	7	263	22495	2983390	1.399	0.742	2.452	1.677	1.822	1.677	0.177	1.3939907	0.3357577
Infliximab	Gastric polyps	Benign neoplasms gastrointestinal (excl oral cavity)	Benign neoplasms gastrointestinal	Gastr	1968-2006	4	242	22498	2983411	1.016	0.444	2.065	1.214	0.142	1.214	0.706	0.80437666	0.01587335
Infliximab	Gastric ulcer	Gastric ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	45	4577	22457	2979076	0.989	0.77	1.254	1.002	0	1.002	0.989	0.35682049	-0.0110609
Infliximab	Gastric ulcer haemorrhage	Gastric ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	6	2174	22496	2981479	0.31	0.156	0.564	0.298	9.945	0.297	0.002	-1.3187334	-1.171183
Infliximab	Gastric ulcer perforation	Gastric ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	10	739	22492	2982914	1.55	0.91	2.503	1.801	3.405	1.801	0.065	0.72434961	0.43825493
Infliximab	Gastritis	Gastritis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	65	6571	22437	2977082	1.034	0.841	1.262	1.046	0.129	1.046	0.719	0.36724302	0.03343478
Infliximab	Gastritis atrophic	Gastritis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	3	81	22499	2983572	1.568	0.609	3.469	2.755	3.182	2.755	0.074	1.28534125	0.44980092
Infliximab	Gastritis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	5	22501	2983648	1.228	0.283	3.849	10.005	5.779	10.005	0.016	0.92577585	0.20538683
Infliximab	Gastritis erosive	Gastric ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	14	1098	22488	2982555	0.829	0.528	1.251	0.852	0.354	0.851	0.552	0.67462346	-0.1875351
Infliximab	Gastritis haemorrhagic	Gastritis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	6	825	22496	2982828	0.993	0.501	1.809	1.106	0.061	1.106	0.805	-0.0559401	-0.0070246
Infliximab	Gastroenteritis	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	77	2460	22425	2981193	2.647	2.188	3.178	2.871	86.81	2.878	1.195e-20	1.95214896	0.97342692
Infliximab	Gastroenteritis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	3	54	22499	2983599	1.698	0.66	3.758	3.329	4.468	3.33	0.035	1.47648913	0.52945109
Infliximab	Gastroenteritis clostridial	Clostridia infections	Bacterial infectious disorders	Infec	1968-2006	2	60	22500	2983593	1.492	0.483	3.745	3.645	3.595	3.645	0.058	1.0240899	0.4001175
Infliximab	Gastroenteritis cryptosporidial	Cryptosporidia infections	Protozoal infectious disorders	Infec	1968-2006	1	48	22501	2983605	0.806	0.186	2.516	1.296	0.068	1.296	0.795	0.53835564	-0.2156715
Infliximab	Gastroenteritis eosinophilic	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	2	48	22500	2983605	1.4	0.454	3.514	3.056	2.582	3.056	0.108	1.11543829	0.33647224
Infliximab	Gastroenteritis escherichia coli	Escherichia infections	Bacterial infectious disorders	Infec	1968-2006	1	24	22501	2983629	1.07	0.248	3.345	3.387	1.552	3.387	0.213	0.74166694	0.06765865
Infliximab	Gastroenteritis radiation	Radiation injuries	Injuries by physical agents	Inj&P	1968-2006	2	57	22500	2983596	1.249	0.405	3.133	2.32	1.373	2.32	0.241	1.04639056	0.22234323
Infliximab	Gastroenteritis rotavirus	Rotaviral infections	Viral infectious disorders	Infec	1968-2006	2	63	22500	2983590	1.186	0.384	2.973	2.032	0.999	2.032	0.318	1.00212868	0.1705863
Infliximab	Gastroenteritis salmonella	Salmonella infections	Bacterial infectious disorders	Infec	1968-2006	10	66	22492	2983587	4.789	2.754	8.189	9.646	69.583	9.651	7.327e-17	2.798819	1.56632162
Infliximab	Gastroenteritis shigella	Shigella infections	Bacterial infectious disorders	Infec	1968-2006	2	13	22500	2983640	1.875	0.605	4.748	9.452	13.189	9.457	0.0002817	1.4205959	0.62860866
Infliximab	Gastroenteritis staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	29	22501	2983624	0.957	0.221	2.989	2.14	0.581	2.14	0.446	0.69688322	-0.0439519
Infliximab	Gastroenteritis viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	18	595	22484	2983058	1.528	1.027	2.204	1.67	4.576	1.671	0.032	1.75434	0.42395969
Infliximab	Gastroenteritis yersinia	Yersinia infections	Bacterial infectious disorders	Infec	1968-2006	1	4	22501	2983649	1.304	0.3	4.107	22.624	13.343	22.624	0.0002593	0.93614837	0.26543646
Infliximab	Gastrointestinal amyloidosis	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	3	4	22499	2983649	2.946	1.086	7.484	29.661	49.724	29.669	1.77e-12	1.91547742	1.08044832
Infliximab	Gastrointestinal angiodysplasia	Vascular anomalies congenital NEC	Cardiac and vascular disorders congenital	Cong	1968-2006	1	46	22501	2983607	0.849	0.196	2.65	1.478	0.155	1.478	0.694	0.5542459	-0.1636961
Infliximab	Gastrointestinal arteriovenous malformation	Vascular anomalies congenital NEC	Cardiac and vascular disorders congenital	Cong	1968-2006	1	34	22501	2983619	0.981	0.227	3.065	2.3	0.73	2.301	0.393	0.65344776	-0.0191828
Infliximab	Gastrointestinal candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	3	214	22499	2983439	1.601	0.622	3.542	2.892	3.472	2.892	0.062	0.59711774	0.47062843
Infliximab	Gastrointestinal carcinoma	Gastrointestinal neoplasms malignant NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	8	1940	22494	2981713	1.755	0.969	2.98	2.206	4.988	2.206	0.026	-0.8036033	0.56246886
Infliximab	Gastrointestinal disorder	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	84	11319	22418	2972334	0.946	0.788	1.127	0.951	0.209	0.951	0.648	-0.0391388	-0.0555127
Infliximab	Gastrointestinal disorder postoperative	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	17	22501	2983636	1.105	0.255	3.454	4.174	2.046	4.174	0.153	0.80679534	0.09984533
Infliximab	Gastrointestinal dysplasia	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	3	15	22499	2983638	2.389	0.922	5.353	10.123	18.946	10.123	0.00001345	1.80679546	0.87087487
Infliximab	Gastrointestinal erosion	Gastrointestinal ulcers and perforation, site unspecified	Gastrointestinal ulceration and perforation	Gastr	1968-2006	2	50	22500	2983603	1.354	0.439	3.396	2.767	2.145	2.767	0.143	1.09980628	0.30306317
Infliximab	Gastrointestinal fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	4	35	22498	2983618	2.72	1.181	5.594	8.357	21.524	8.358	3.494e-6	1.94154539	1.00063188
Infliximab	Gastrointestinal fungal infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	2	24	22500	2983629	1.56	0.505	3.919	4.246	4.566	4.246	0.033	1.31756088	0.44468582
Infliximab	Gastrointestinal haemorrhage	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	125	20583	22377	2963070	0.796	0.686	0.92	0.795	6.56	0.793	0.01	-0.3290014	-0.2281561
Infliximab	Gastrointestinal hypomotility	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	2	121	22500	2983532	0.763	0.247	1.911	0.916	0.015	0.916	0.902	0.63243733	-0.2704972
Infliximab	Gastrointestinal infection	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	16	447	22486	2983206	2	1.313	2.945	2.306	11.261	2.307	0.001	1.91752059	0.69314718
Infliximab	Gastrointestinal inflammation	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	3	103	22499	2983550	1.348	0.524	2.981	2.071	1.558	2.071	0.212	1.14637841	0.29862201
Infliximab	Gastrointestinal malformation	Gastrointestinal tract disorders congenital NEC	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	76	22501	2983577	0.841	0.194	2.624	1.459	0.135	1.459	0.713	0.33251843	-0.1731636
Infliximab	Gastrointestinal motility disorder	Gastrointestinal dyskinetic disorders	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	1	336	22501	2983317	0.251	0.058	0.783	0.201	3.203	0.201	0.074	-0.8276212	-1.3823023
Infliximab	Gastrointestinal mucosal disorder	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	1	71	22501	2983582	0.595	0.138	1.856	0.689	0.138	0.689	0.71	0.36718681	-0.5191939
Infliximab	Gastrointestinal necrosis	Gastrointestinal necrosis and gangrene (excl gangrenous hernia)	Gastrointestinal vascular conditions	Gastr	1968-2006	14	922	22488	2982731	1.459	0.93	2.202	1.609	3.106	1.609	0.078	0.89447887	0.37775127
Infliximab	Gastrointestinal neoplasm	Gastrointestinal neoplasms malignancy unspecified NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	175	22501	2983478	0.736	0.17	2.297	1.051	0.002	1.051	0.961	-0.2234399	-0.3065252
Infliximab	Gastrointestinal obstruction	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	9	144	22493	2983509	2.962	1.689	4.904	4.557	23.129	4.559	1.515e-6	2.20987002	1.08586472
Infliximab	Gastrointestinal oedema	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	1	95	22501	2983558	0.54	0.125	1.685	0.581	0.295	0.581	0.587	0.20788933	-0.6161861
Infliximab	Gastrointestinal pain	Gastrointestinal and abdominal pains (excl oral and throat)	Gastrointestinal signs and symptoms	Gastr	1968-2006	3	624	22499	2983029	0.316	0.123	0.698	0.295	5.012	0.294	0.025	-0.5204029	-1.1520131
Infliximab	Gastrointestinal perforation	Gastrointestinal ulcers and perforation, site unspecified	Gastrointestinal ulceration and perforation	Gastr	1968-2006	3	352	22499	2983301	0.655	0.255	1.449	0.703	0.369	0.703	0.544	0.1182177	-0.42312
Infliximab	Gastrointestinal stoma complication	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	9	50	22493	2983603	4.414	2.481	7.59	10.113	58.588	10.116	1.944e-14	2.78335721	1.48478131
Infliximab	Gastrointestinal stromal tumour	Gastrointestinal neoplasms malignancy unspecified NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	51	22501	2983602	0.742	0.172	2.316	1.069	0.004	1.069	0.947	0.51484364	-0.298406
Infliximab	Gastrointestinal toxicity	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	1	104	22501	2983549	0.564	0.13	1.759	0.626	0.218	0.626	0.641	0.15241245	-0.572701
Infliximab	Gastrointestinal tract adenoma	Gastrointestinal neoplasms benign NEC	Gastrointestinal neoplasms benign	Neopl	1968-2006	9	24	22493	2983629	7.665	3.46	19.316	22.144	119.42	22.153	8.476e-28	2.99259424	2.03666451
Infliximab	Gastrointestinal tube insertion	Gastrointestinal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	52	22501	2983601	0.801	0.185	2.5	1.282	0.059	1.282	0.808	0.50709068	-0.2218943
Infliximab	Gastrointestinal ulcer	Gastrointestinal ulcers and perforation, site unspecified	Gastrointestinal ulceration and perforation	Gastr	1968-2006	10	468	22492	2983185	1.336	0.784	2.157	1.5	1.602	1.5	0.206	1.25365517	0.28968008
Infliximab	Gastrointestinal ulcer haemorrhage	Gastrointestinal ulcers and perforation, site unspecified	Gastrointestinal ulceration and perforation	Gastr	1968-2006	3	126	22499	2983527	0.967	0.376	2.138	1.198	0.096	1.198	0.757	1.01412582	-0.0335568
Infliximab	Gastrointestinal ulcer perforation	Gastrointestinal ulcers and perforation, site unspecified	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	44	22501	2983609	0.942	0.218	2.942	2.001	0.502	2.002	0.479	0.5703131	-0.05975
Infliximab	Gastrooesophageal reflux disease	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	63	5817	22439	2977836	0.751	0.608	0.918	0.749	5.167	0.749	0.023	0.494056	-0.2863496
Infliximab	Gastrooesophagitis	Oesophagitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	1	17	22501	2983636	1.043	0.241	3.258	3.047	1.247	3.047	0.264	0.80679534	0.04210118
Infliximab	General nutrition disorder				1968-2006	2	56	22500	2983597	1.125	0.365	2.822	1.821	0.705	1.822	0.401	1.05390137	0.11778304
Infliximab	General physical condition	Physical examination procedures	Physical examination topics	Inv	1968-2006	2	9	22500	2983644	2.07	0.66	5.339	17.513	26.899	17.518	2.143e-7	1.45996566	0.72754861
Infliximab	General physical condition abnormal	Physical examination procedures	Physical examination topics	Inv	1968-2006	4	262	22498	2983391	0.855	0.373	1.737	0.962	0.006	0.962	0.939	0.73028951	-0.1566538
Infliximab	General physical health deterioration	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	100	5247	22402	2978406	1.031	0.873	1.212	1.039	0.143	1.039	0.705	1.28643829	0.03052921
Infliximab	Generalised erythema	Erythemas	Epidermal and dermal conditions	Skin	1968-2006	9	556	22493	2983097	0.846	0.483	1.398	0.886	0.127	0.886	0.722	0.92422966	-0.1672359
Infliximab	Generalised oedema	Oedema NEC	General system disorders NEC	Genrl	1968-2006	13	1215	22489	2982438	0.545	0.341	0.834	0.544	4.935	0.543	0.026	0.44656873	-0.6069695
Infliximab	Genital candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	2	73	22500	2983580	0.869	0.282	2.179	1.129	0.029	1.129	0.865	0.93124866	-0.1404122
Infliximab	Genital disorder female	Reproductive tract disorders NEC (excl neoplasms)	Reproductive tract disorders NEC	Repro	1968-2006	2	155	22500	2983498	0.854	0.277	2.14	1.097	0.016	1.097	0.899	0.45290425	-0.1578241
Infliximab	Genital haemorrhage	Reproductive tract disorders NEC (excl neoplasms)	Reproductive tract disorders NEC	Repro	1968-2006	1	156	22501	2983497	0.418	0.097	1.304	0.388	0.939	0.388	0.332	-0.1320585	-0.8722738
Infliximab	Genital neoplasm malignant female	Female reproductive neoplasms malignant NEC	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	1	10	22501	2983643	1.232	0.284	3.865	9.731	6.007	9.733	0.014	0.87500312	0.20863887
Infliximab	Genital pruritus female	Vulvovaginal signs and symptoms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	3	1045	22499	2982608	0.229	0.089	0.507	0.207	9.027	0.207	0.003	-1.1561415	-1.4740333
Infliximab	Genital pruritus male	Reproductive tract signs and symptoms NEC	Reproductive tract disorders NEC	Repro	1968-2006	1	32	22501	2983621	1.096	0.253	3.425	3.901	1.896	3.901	0.168	0.67066536	0.09166719
Infliximab	Genital ulceration	Reproductive tract disorders NEC (excl neoplasms)	Reproductive tract disorders NEC	Repro	1968-2006	1	146	22501	2983507	0.527	0.122	1.645	0.558	0.341	0.558	0.559	-0.0815331	-0.6405547
Infliximab	Germ cell cancer	Germ cell neoplasms site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	1	35	22501	2983618	0.894	0.207	2.791	1.733	0.292	1.733	0.589	0.64491541	-0.1120495
Infliximab	Gestational diabetes	Diabetes mellitus (incl subtypes)	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	3	223	22499	2983430	0.728	0.283	1.609	0.806	0.137	0.806	0.711	0.56054588	-0.3174542
Infliximab	Giardiasis	Giardia infections	Protozoal infectious disorders	Infec	1968-2006	1	55	22501	2983598	0.789	0.183	2.463	1.23	0.043	1.23	0.835	0.48407867	-0.236989
Infliximab	Gilberts syndrome	Inborn errors of bilirubin metabolism	Metabolic and nutritional disorders congenital	Cong	1968-2006	2	63	22500	2983590	1.209	0.392	3.033	2.123	1.128	2.123	0.288	1.00212868	0.18979357
Infliximab	Gingival abscess	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	30	22501	2983623	0.92	0.213	2.873	1.906	0.397	1.906	0.529	0.68809089	-0.0833816
Infliximab	Gingival bleeding	Gingival haemorrhages	Dental and gingival conditions	Gastr	1968-2006	3	2395	22499	2981258	0.187	0.072	0.412	0.166	12.458	0.166	0.0004162	-2.2561055	-1.6766467
Infliximab	Gingival disorder	Gingival disorders NEC	Dental and gingival conditions	Gastr	1968-2006	1	242	22501	2983411	0.26	0.06	0.812	0.207	3.003	0.207	0.083	-0.5061038	-1.3470736
Infliximab	Gingival hyperplasia	Gingival disorders NEC	Dental and gingival conditions	Gastr	1968-2006	2	1253	22500	2982400	0.522	0.169	1.309	0.537	0.793	0.537	0.373	-1.8041698	-0.6500877
Infliximab	Gingival hypertrophy	Gingival disorders NEC	Dental and gingival conditions	Gastr	1968-2006	1	104	22501	2983549	0.602	0.139	1.879	0.706	0.122	0.705	0.727	0.15241245	-0.5074978
Infliximab	Gingival infection	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	187	22501	2983466	0.417	0.096	1.303	0.387	0.939	0.387	0.333	-0.2783085	-0.8746691
Infliximab	Gingival pain	Gingival pains	Dental and gingival conditions	Gastr	1968-2006	4	576	22498	2983077	0.469	0.205	0.953	0.464	2.43	0.464	0.119	-0.1064287	-0.7571525
Infliximab	Gingival recession	Gingival disorders NEC	Dental and gingival conditions	Gastr	1968-2006	3	121	22499	2983532	1.23	0.478	2.72	1.762	0.931	1.762	0.335	1.04186306	0.20701417
Infliximab	Gingivitis	Gingival disorders NEC	Dental and gingival conditions	Gastr	1968-2006	4	2587	22498	2981066	0.426	0.186	0.866	0.418	3.203	0.418	0.074	-2.0402655	-0.8533159
Infliximab	Glasgow coma scale abnormal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	160	22501	2983493	0.453	0.105	1.415	0.44	0.695	0.44	0.405	-0.1517835	-0.7918632
Infliximab	Glaucoma	Glaucomas (excl congenital)	Glaucoma and ocular hypertension	Eye	1968-2006	21	3313	22481	2980340	0.826	0.572	1.162	0.84	0.627	0.84	0.428	-0.2510072	-0.1911605
Infliximab	Glioblastoma	Glial tumours malignant	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	5	109	22497	2983544	1.739	0.825	3.323	2.551	4.322	2.552	0.038	1.68395318	0.55331024
Infliximab	Glioblastoma multiforme	Glial tumours malignant	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	5	121	22497	2983532	1.524	0.723	2.911	2.044	2.559	2.044	0.11	1.61566707	0.42133846
Infliximab	Glioma	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	8	65	22494	2983588	3.685	2.023	6.334	7.831	38.716	7.834	4.901e-10	2.53011239	1.30427053
Infliximab	Gliosis	Central nervous system inflammatory disorders NEC	Central nervous system infections and inflammations	Nerv	1968-2006	3	99	22499	2983554	1.296	0.503	2.865	1.918	1.262	1.918	0.261	1.17066919	0.2592826
Infliximab	Glomerular vascular disorder	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	43	22501	2983610	0.867	0.201	2.707	1.592	0.205	1.592	0.651	0.5784143	-0.1427163
Infliximab	Glomerulonephritis	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	10	943	22492	2982710	1.482	0.87	2.393	1.695	2.769	1.695	0.096	0.4242603	0.39339253
Infliximab	Glomerulonephritis membranoproliferative	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	2	43	22500	2983610	1.458	0.472	3.66	3.35	3.184	3.35	0.074	1.15527573	0.37706563
Infliximab	Glomerulonephritis membranous	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	3	139	22499	2983514	1.052	0.409	2.326	1.36	0.279	1.36	0.598	0.94440935	0.05069311
Infliximab	Glomerulonephritis minimal lesion	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	1	53	22501	2983600	0.75	0.174	2.341	1.097	0.008	1.097	0.927	0.49937916	-0.2876821
Infliximab	Glomerulonephritis proliferative	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	13	249	22489	2983404	2.894	1.814	4.433	3.877	25.56	3.878	4.288e-7	2.2302355	1.06263963
Infliximab	Glomerulonephritis rapidly progressive	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	1	83	22501	2983570	0.632	0.146	1.974	0.771	0.067	0.771	0.796	0.28534087	-0.4588659
Infliximab	Glomerulonephropathy	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	1	28	22501	2983625	0.907	0.21	2.831	1.809	0.341	1.809	0.559	0.70572945	-0.0976128
Infliximab	Glomerulosclerosis	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	2	86	22500	2983567	0.859	0.278	2.153	1.108	0.02	1.108	0.887	0.84402174	-0.1519864
Infliximab	Glomus tumour	Soft tissue neoplasms benign NEC	Soft tissue neoplasms benign	Neopl	1968-2006	1	3	22501	2983650	1.356	0.31	4.301	51.223	31.736	51.223	1.766e-8	0.946596	0.30453919
Infliximab	Glossitis	Tongue disorders	Tongue conditions	Gastr	1968-2006	3	4332	22499	2979321	0.314	0.122	0.694	0.295	5.043	0.295	0.025	-3.0768177	-1.1583623
Infliximab	Glossodynia	Tongue signs and symptoms	Tongue conditions	Gastr	1968-2006	6	1490	22496	2982163	0.288	0.145	0.524	0.275	11.439	0.275	0.001	-0.8127797	-1.2447948
Infliximab	Glottis carcinoma	Laryngeal neoplasms malignant	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	6	22501	2983647	1.258	0.29	3.949	12.961	7.757	12.961	0.005	0.91547736	0.22952316
Infliximab	Glucose tolerance impaired	Hyperglycaemic conditions NEC	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	3	382	22499	2983271	0.539	0.21	1.192	0.549	1.078	0.549	0.299	0.03223405	-0.6180397
Infliximab	Glucose tolerance test abnormal	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	25	22501	2983628	0.978	0.226	3.053	2.362	0.709	2.362	0.4	0.7325983	-0.0222456
Infliximab	Glucose urine	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	57	22501	2983596	0.87	0.201	2.715	1.575	0.211	1.575	0.646	0.46893872	-0.1392621
Infliximab	Glucose urine present	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	466	22501	2983187	0.224	0.052	0.7	0.173	3.901	0.173	0.048	-1.1795904	-1.4961092
Infliximab	Glutathione decreased	Haematological analyses NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	1	1	22501	2983652	1.304	0.3	4.109	25.876	13.642	25.876	0.0002212	0.967721	0.26543646
Infliximab	Glycogen storage disease type VIII	Inborn errors of carbohydrate metabolism (excl glucose)	Metabolic and nutritional disorders congenital	Cong	1968-2006	2	3	22500	2983650	2.322	0.708	6.573	49.541	64.193	49.58	1.128e-15	1.5211109	0.84242888
Infliximab	Glycosylated haemoglobin increased	Carbohydrate tolerance analyses (incl diabetes)	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	4	1201	22498	2982452	0.233	0.102	0.474	0.216	11.303	0.216	0.001	-1.0142728	-1.4567168
Infliximab	Goitre	Thyroid disorders NEC	Thyroid gland disorders	Endo	1968-2006	14	753	22488	2982900	1.693	1.079	2.555	1.922	5.876	1.922	0.015	1.14267465	0.5265021
Infliximab	Gout	Purine metabolism disorders NEC	Purine and pyrimidine metabolism disorders	Metab	1968-2006	7	1893	22495	2981760	0.46	0.244	0.807	0.455	4.501	0.455	0.034	-0.9398485	-0.7765288
Infliximab	Gouty arthritis	Crystal arthropathic disorders	Joint disorders	Musc	1968-2006	2	120	22500	2983533	0.913	0.296	2.289	1.226	0.081	1.226	0.776	0.63807125	-0.0910194
Infliximab	Gouty tophus	Crystal arthropathic disorders	Joint disorders	Musc	1968-2006	1	16	22501	2983637	1.093	0.253	3.418	3.626	1.868	3.627	0.172	0.81634411	0.08892621
Infliximab	Graft complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	178	22501	2983475	0.333	0.077	1.041	0.288	1.767	0.287	0.184	-0.2373539	-1.0996128
Infliximab	Graft infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	3	46	22499	2983607	1.835	0.713	4.064	3.893	6.126	3.894	0.013	1.53835591	0.60704448
Infliximab	Graft versus host disease	Transplant rejections	Immune disorders NEC	Immun	1968-2006	20	1460	22482	2982193	0.84	0.576	1.191	0.856	0.477	0.856	0.49	0.78643169	-0.1743534
Infliximab	Gram stain negative	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	23	22501	2983630	0.981	0.227	3.063	2.322	0.729	2.322	0.393	0.75079293	-0.0191828
Infliximab	Gram stain positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	6	136	22496	2983517	2.468	1.245	4.502	4.131	13.324	4.133	0.0002621	1.75176502	0.90340811
Infliximab	Grand mal convulsion	Generalised tonic-clonic seizures	Seizures (incl subtypes)	Nerv	1968-2006	43	12869	22459	2970784	0.48	0.372	0.612	0.476	24.822	0.475	6.287e-7	-1.1671956	-0.7339692
Infliximab	Granulocyte count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	101	22501	2983552	0.53	0.122	1.653	0.564	0.331	0.564	0.565	0.17066877	-0.6348783
Infliximab	Granulocytopenia	Neutropenias	White blood cell disorders	Blood	1968-2006	2	1040	22500	2982613	0.15	0.049	0.376	0.125	12.105	0.125	0.001	-1.5638321	-1.89712
Infliximab	Granuloma	Inflammations	General system disorders NEC	Genrl	1968-2006	80	1358	22422	2982295	5.74	4.757	6.881	6.955	355.502	6.978	0	2.77206017	1.74745921
Infliximab	Granuloma annulare	Granulomatous and deep cutaneous inflammatory conditions	Epidermal and dermal conditions	Skin	1968-2006	1	40	22501	2983613	0.869	0.201	2.712	1.586	0.209	1.586	0.647	0.60299444	-0.1404122
Infliximab	Granuloma inguinale	Calymmatobacteria infections	Bacterial infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.375	0.313	4.373	1088.649	88.243	1096.389	5.789e-21	0.97840063	0.31845373
Infliximab	Granuloma skin	Granulomatous and deep cutaneous inflammatory conditions	Epidermal and dermal conditions	Skin	1968-2006	3	13	22499	2983640	2.75	1.039	6.449	18.693	36.779	18.698	1.323e-9	1.8259566	1.01160091
Infliximab	Granulomatous liver disease	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	12	226	22490	2983427	2.803	1.723	4.362	3.888	22.785	3.889	1.812e-6	2.21362451	1.03069027
Infliximab	Gravitational oedema	Oedema NEC	General system disorders NEC	Genrl	1968-2006	3	79	22499	2983574	1.299	0.505	2.873	1.918	1.286	1.919	0.257	1.29866388	0.26159474
Infliximab	Grip strength decreased	Physical examination procedures	Physical examination topics	Inv	1968-2006	1	119	22501	2983534	0.506	0.117	1.58	0.523	0.425	0.523	0.515	0.06444279	-0.6812186
Infliximab	Groin abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	2	37	22500	2983616	1.337	0.433	3.353	2.746	2.017	2.746	0.156	1.20457957	0.2904283
Infliximab	Groin pain	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	16	700	22486	2982953	1.475	0.968	2.172	1.612	3.561	1.612	0.059	1.4073755	0.38865799
Infliximab	Growth retardation	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	727	22501	2982926	0.199	0.046	0.621	0.153	4.754	0.153	0.029	-1.7003339	-1.6144505
Infliximab	Grunting	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	1	121	22501	2983532	0.549	0.127	1.712	0.602	0.265	0.602	0.607	0.05310852	-0.5996568
Infliximab	Guillain-Barre syndrome	Acute polyneuropathies	Peripheral neuropathies	Nerv	1968-2006	27	1092	22475	2982561	2.346	1.698	3.176	2.651	25.926	2.653	3.547e-7	1.56700506	0.85271175
Infliximab	Gun shot wound	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	3	719	22499	2982934	0.263	0.102	0.582	0.243	7.085	0.242	0.008	-0.6902483	-1.3356012
Infliximab	Guttate psoriasis	Psoriatic conditions	Epidermal and dermal conditions	Skin	1968-2006	2	26	22500	2983627	1.646	0.533	4.139	4.963	6.08	4.964	0.014	1.29959284	0.4983481
Infliximab	Gynaecomastia	Breast disorders NEC	Breast disorders	Repro	1968-2006	2	4529	22500	2979124	0.196	0.064	0.492	0.169	8.15	0.169	0.004	-3.5538811	-1.6296406
Infliximab	HBV-DNA polymerase increased	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	3	22501	2983650	1.283	0.296	4.034	16.155	10.255	16.163	0.001	0.946596	0.24920109
Infliximab	HIV infection	Retroviral infections	Viral infectious disorders	Infec	1968-2006	1	1888	22501	2981765	0.086	0.02	0.268	0.06	15.01	0.06	0.0001069	-2.932021	-2.453408
Infliximab	HIV test positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	3	956	22499	2982697	0.807	0.313	1.783	0.927	0.017	0.927	0.895	-1.0431216	-0.2144316
Infliximab	HLA marker study	Cell marker procedures	Immunology and allergy investigations	Inv	1968-2006	1	5	22501	2983648	1.281	0.295	4.03	17.087	10.085	17.087	0.001	0.92577585	0.24764102
Infliximab	Haemangioblastoma	Nervous system neoplasms benign NEC	Nervous system neoplasms benign	Neopl	1968-2006	1	5	22501	2983648	1.269	0.293	3.989	14.467	8.831	14.467	0.003	0.92577585	0.23822919
Infliximab	Haemangioma	Cardiovascular neoplasms benign	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	3	354	22499	2983299	0.546	0.212	1.206	0.559	1.03	0.559	0.31	0.11232331	-0.6051363
Infliximab	Haemangioma of liver	Hepatobiliary neoplasms benign	Hepatic and biliary neoplasms benign	Neopl	1968-2006	7	200	22495	2983453	1.655	0.878	2.901	2.099	3.832	2.099	0.05	1.63887188	0.50380101
Infliximab	Haemarthrosis	Arthropathies NEC	Joint disorders	Musc	1968-2006	5	251	22497	2983402	1.138	0.54	2.174	1.35	0.447	1.35	0.504	1.02989241	0.12927234
Infliximab	Haematemesis	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	30	7619	22472	2976034	0.421	0.31	0.562	0.416	24.528	0.415	7.325e-7	-0.9246441	-0.8651224
Infliximab	Haematochezia	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	45	3953	22457	2979700	0.761	0.592	0.964	0.762	3.285	0.762	0.07	0.56004956	-0.2731219
Infliximab	Haematocrit	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	15	180	22487	2983473	2.558	1.656	3.813	3.202	21.01	3.214	4.568e-6	2.69062664	0.9392257
Infliximab	Haematocrit abnormal	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	6	117	22496	2983536	1.634	0.825	2.976	2.164	3.506	2.165	0.061	1.85483069	0.491031
Infliximab	Haematocrit decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	115	7243	22387	2976410	1.153	0.987	1.34	1.165	2.631	1.166	0.105	1.03430046	0.14236724
Infliximab	Haematoma	Haemorrhages NEC	Vascular haemorrhagic disorders	Vasc	1968-2006	44	4322	22458	2979331	0.742	0.576	0.943	0.743	3.861	0.742	0.049	0.40506579	-0.298406
Infliximab	Haematoma infection	Vascular infections	Infections - pathogen class unspecified	Infec	1968-2006	3	45	22499	2983608	1.795	0.697	3.975	3.846	5.6	3.846	0.018	1.54627915	0.58500502
Infliximab	Haematotoxicity	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	1	338	22501	2983315	0.207	0.048	0.646	0.157	4.483	0.157	0.034	-0.8337406	-1.5750365
Infliximab	Haematuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	50	8352	22452	2975301	0.859	0.678	1.077	0.864	1.047	0.864	0.306	-0.340011	-0.1519864
Infliximab	Haemobilia	Hepatic and hepatobiliary disorders NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	1	15	22501	2983638	1.124	0.26	3.514	4.321	2.374	4.321	0.123	0.82595649	0.11689375
Infliximab	Haemochromatosis	Iron excess	Iron and trace metal metabolism disorders	Metab	1968-2006	2	185	22500	2983468	0.789	0.256	1.978	0.966	0.002	0.966	0.961	0.31114783	-0.236989
Infliximab	Haemodialysis	Haematological therapeutic procedures NEC	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	28	4840	22474	2978813	0.379	0.276	0.511	0.372	29.384	0.371	5.936e-8	-0.38165	-0.9702191
Infliximab	Haemodynamic instability	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	13	652	22489	2983001	1.04	0.652	1.592	1.097	0.11	1.098	0.74	1.21660217	0.03922071
Infliximab	Haemoglobin	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	29	359	22473	2983294	2.692	1.97	3.608	3.123	38.437	3.143	5.655e-10	2.93081084	0.99028441
Infliximab	Haemoglobin abnormal	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	14	450	22488	2983203	1.277	0.814	1.928	1.382	1.421	1.382	0.233	1.73453092	0.24451358
Infliximab	Haemoglobin decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	208	15999	22294	2967654	0.924	0.823	1.034	0.924	1.274	0.924	0.259	0.75431271	-0.0790432
Infliximab	Haemoglobin increased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	5	399	22497	2983254	0.818	0.388	1.563	0.889	0.068	0.889	0.794	0.5652767	-0.2008929
Infliximab	Haemolysis	Haemolyses NEC	Haemolyses and related conditions	Blood	1968-2006	7	1835	22495	2981818	0.467	0.247	0.818	0.463	4.335	0.463	0.037	-0.8980753	-0.761426
Infliximab	Haemolytic anaemia	Anaemias haemolytic NEC	Haemolyses and related conditions	Blood	1968-2006	29	4909	22473	2978744	0.964	0.705	1.292	0.983	0.009	0.983	0.926	-0.3528251	-0.036664
Infliximab	Haemolytic uraemic syndrome	Anaemias haemolytic mechanical factor	Haemolyses and related conditions	Blood	1968-2006	5	717	22497	2982936	0.507	0.24	0.968	0.507	2.364	0.507	0.124	-0.105285	-0.6792443
Infliximab	Haemophilia	Coagulation disorders congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	3	22	22499	2983631	2.502	0.962	5.649	12.034	23.457	12.037	1.277e-6	1.74166709	0.91709041
Infliximab	Haemophilus infection	Haemophilus infections	Bacterial infectious disorders	Infec	1968-2006	17	174	22485	2983479	4.604	3.049	6.764	7.187	76.68	7.192	2.011e-18	2.87822385	1.52692549
Infliximab	Haemophilus sepsis	Haemophilus infections	Bacterial infectious disorders	Infec	1968-2006	1	10	22501	2983643	1.13	0.261	3.535	4.53	2.517	4.53	0.113	0.87500312	0.12221763
Infliximab	Haemoptysis	Coughing and associated symptoms	Respiratory disorders NEC	Resp	1968-2006	42	4383	22460	2979270	0.975	0.753	1.247	0.989	0.005	0.989	0.943	0.32065386	-0.0253178
Infliximab	Haemorrhage	Haemorrhages NEC	Vascular haemorrhagic disorders	Vasc	1968-2006	105	18613	22397	2965040	0.697	0.592	0.816	0.694	14.047	0.692	0.0001783	-0.4326229	-0.3609699
Infliximab	Haemorrhage intracranial	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	8	3622	22494	2980031	0.277	0.153	0.47	0.268	16.132	0.267	0.00005908	-1.6588391	-1.2837378
Infliximab	Haemorrhage subcutaneous	Skin haemorrhages	Skin vascular abnormalities	Skin	1968-2006	2	489	22500	2983164	0.29	0.094	0.727	0.264	4.165	0.264	0.041	-0.6511677	-1.2378744
Infliximab	Haemorrhage urinary tract	Urinary tract signs and symptoms NEC	Urinary tract signs and symptoms	Renal	1968-2006	1	116	22501	2983537	0.498	0.115	1.555	0.508	0.461	0.508	0.497	0.0816129	-0.6971552
Infliximab	Haemorrhagic cerebral infarction	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	5	112	22497	2983541	1.701	0.807	3.25	2.444	3.978	2.445	0.046	1.66657631	0.53121631
Infliximab	Haemorrhagic cyst	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	1	20	22501	2983633	1.107	0.256	3.461	4.129	2.072	4.129	0.15	0.77852244	0.10165365
Infliximab	Haemorrhagic diathesis	Bleeding tendencies	Coagulopathies and bleeding diatheses (excl thrombocytopenic)	Blood	1968-2006	4	422	22498	2983231	0.642	0.28	1.304	0.673	0.628	0.673	0.428	0.24436798	-0.443167
Infliximab	Haemorrhagic infarction	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	47	22501	2983606	0.91	0.21	2.84	1.841	0.351	1.841	0.553	0.54627889	-0.0943107
Infliximab	Haemorrhagic ovarian cyst	Ovarian and fallopian tube cysts and neoplasms	Ovarian and fallopian tube disorders	Repro	1968-2006	1	61	22501	2983592	0.655	0.152	2.046	0.829	0.036	0.829	0.85	0.43912725	-0.42312
Infliximab	Haemorrhagic stroke	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	26	5977	22476	2977676	0.749	0.539	1.02	0.755	2.04	0.754	0.153	-0.7803443	-0.2890163
Infliximab	Haemorrhoid operation	Anorectal therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	55	22501	2983598	0.833	0.193	2.6	1.413	0.117	1.413	0.732	0.48407867	-0.1827216
Infliximab	Haemorrhoidal haemorrhage	Haemorrhoids and gastrointestinal varices (excl oesophageal)	Gastrointestinal vascular conditions	Gastr	1968-2006	3	225	22499	2983428	0.722	0.28	1.595	0.798	0.152	0.798	0.697	0.55254315	-0.3257301
Infliximab	Haemorrhoids	Haemorrhoids and gastrointestinal varices (excl oesophageal)	Gastrointestinal vascular conditions	Gastr	1968-2006	25	1950	22477	2981703	0.849	0.607	1.163	0.861	0.542	0.861	0.462	0.70831349	-0.1636961
Infliximab	Haemothorax	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	8	463	22494	2983190	1.305	0.72	2.216	1.493	1.277	1.494	0.258	0.98075873	0.26620304
Infliximab	Hair colour changes	Pilar disorders NEC	Skin appendage conditions	Skin	1968-2006	1	1899	22501	2981754	0.295	0.068	0.921	0.243	2.327	0.243	0.127	-2.9398512	-1.2207799
Infliximab	Hair growth abnormal	Pilar disorders NEC	Skin appendage conditions	Skin	1968-2006	1	446	22501	2983207	0.213	0.049	0.666	0.166	4.256	0.166	0.039	-1.1307204	-1.5464631
Infliximab	Hairy cell leukaemia	Leukaemias chronic lymphocytic	Leukaemias	Neopl	1968-2006	2	42	22500	2983611	1.373	0.445	3.445	2.979	2.326	2.979	0.127	1.16337692	0.31699813
Infliximab	Hallucination	Perception disturbances	Disturbances in thinking and perception	Psych	1968-2006	23	19180	22479	2964473	0.196	0.138	0.271	0.19	79.576	0.189	4.64e-19	-2.6125037	-1.6296406
Infliximab	Hallucination, auditory	Perception disturbances	Disturbances in thinking and perception	Psych	1968-2006	2	1807	22500	2981846	0.083	0.027	0.208	0.067	25.855	0.067	3.681e-7	-2.288797	-2.4889147
Infliximab	Hallucination, visual	Perception disturbances	Disturbances in thinking and perception	Psych	1968-2006	4	2138	22498	2981515	0.125	0.054	0.253	0.113	28.129	0.113	1.135e-7	-1.7802502	-2.0794415
Infliximab	Hallucinations, mixed	Perception disturbances	Disturbances in thinking and perception	Psych	1968-2006	1	520	22501	2983133	0.161	0.037	0.505	0.119	6.527	0.119	0.011	-1.3038266	-1.8263509
Infliximab	Halo vision	Visual disorders NEC	Vision disorders	Eye	1968-2006	1	123	22501	2983530	0.541	0.125	1.688	0.581	0.291	0.581	0.589	0.04186259	-0.614336
Infliximab	Hand amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	26	22501	2983627	0.935	0.216	2.918	1.968	0.464	1.968	0.496	0.72358631	-0.0672087
Infliximab	Hand deformity	Extremity deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	2	68	22500	2983585	1.069	0.346	2.679	1.636	0.478	1.636	0.489	0.96625348	0.06672363
Infliximab	Hangover	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	615	22501	2983038	0.289	0.067	0.902	0.238	2.428	0.238	0.119	-1.4993812	-1.2413286
Infliximab	Haptoglobin increased	Haem metabolism analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	75	22501	2983578	0.724	0.167	2.26	1.014	0	1.014	0.989	0.33938578	-0.3229639
Infliximab	Head discomfort	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	1	196	22501	2983457	0.309	0.071	0.965	0.256	2.111	0.256	0.146	-0.3181327	-1.174414
Infliximab	Head injury	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	23	2514	22479	2981139	0.562	0.396	0.779	0.558	7.909	0.558	0.005	0.25168441	-0.5762534
Infliximab	Headache	Headaches NEC	Headaches	Nerv	1968-2006	643	103845	21859	2879808	0.843	0.789	0.899	0.84	19.99	0.835	7.783e-6	-0.3441276	-0.1707883
Infliximab	Hearing impaired	Hearing losses	Hearing disorders	Ear	1968-2006	17	1320	22485	2982333	0.957	0.636	1.394	0.99	0.002	0.99	0.966	0.69798556	-0.0439519
Infliximab	Heart disease congenital	Cardiac disorders congenital NEC	Cardiac and vascular disorders congenital	Cong	1968-2006	2	742	22500	2982911	0.317	0.103	0.795	0.29	3.459	0.289	0.063	-1.1419241	-1.1488535
Infliximab	Heart rate	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	36	22501	2983617	0.925	0.214	2.887	1.913	0.417	1.914	0.518	0.63643321	-0.0779615
Infliximab	Heart rate abnormal	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	268	22501	2983385	0.278	0.064	0.869	0.226	2.627	0.226	0.105	-0.6024317	-1.2801342
Infliximab	Heart rate decreased	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	33	3207	22469	2980446	0.684	0.511	0.901	0.685	4.729	0.685	0.03	0.4167237	-0.3797974
Infliximab	Heart rate increased	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	172	12279	22330	2971374	0.874	0.77	0.989	0.874	3.091	0.873	0.079	0.86019078	-0.1346749
Infliximab	Heart rate irregular	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	27	2698	22475	2980955	0.64	0.463	0.867	0.639	5.405	0.639	0.02	0.3758427	-0.4462871
Infliximab	Heart sounds abnormal	Cardiac auscultatory investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	4	196	22498	2983457	1.158	0.506	2.353	1.455	0.55	1.455	0.458	0.99076203	0.14669438
Infliximab	Heart valve operation	Cardiac valve therapeutic procedures	Cardiac therapeutic procedures	Surg	1968-2006	1	16	22501	2983637	1.023	0.237	3.197	2.806	1.062	2.806	0.303	0.81634411	0.02273949
Infliximab	Heart valve replacement	Cardiac valve therapeutic procedures	Cardiac therapeutic procedures	Surg	1968-2006	5	132	22497	2983521	1.942	0.921	3.711	3.085	6.358	3.086	0.012	1.55578926	0.66371837
Infliximab	Heat rash	Apocrine and eccrine gland disorders	Skin appendage conditions	Skin	1968-2006	1	110	22501	2983543	0.572	0.132	1.785	0.643	0.195	0.643	0.659	0.11657848	-0.5586163
Infliximab	Heat stroke	Heat injuries (excl thermal burns)	Injuries by physical agents	Inj&P	1968-2006	1	212	22501	2983441	0.406	0.094	1.267	0.374	1.027	0.374	0.311	-0.3863264	-0.9014021
Infliximab	Helicobacter gastritis	Helicobacter infections	Bacterial infectious disorders	Infec	1968-2006	3	516	22499	2983137	0.545	0.212	1.204	0.558	1.032	0.558	0.31	-0.2994102	-0.6069695
Infliximab	Helicobacter infection	Helicobacter infections	Bacterial infectious disorders	Infec	1968-2006	9	394	22493	2983259	1.105	0.631	1.826	1.207	0.314	1.207	0.575	1.30493034	0.09984533
Infliximab	Helicobacter pylori identification test positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	117	22501	2983536	0.506	0.117	1.579	0.528	0.426	0.528	0.514	0.0758668	-0.6812186
Infliximab	Hemianopia	Neurologic visual problems NEC	Neurological disorders of the eye	Nerv	1968-2006	2	259	22500	2983394	0.534	0.173	1.339	0.555	0.717	0.555	0.397	0.01149153	-0.6273594
Infliximab	Hemiparesis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	42	3097	22460	2980556	0.975	0.752	1.246	0.988	0.006	0.988	0.939	0.79943038	-0.0253178
Infliximab	Hemiplegia	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	10	3701	22492	2979952	0.445	0.261	0.718	0.439	7.111	0.438	0.008	-1.400091	-0.809681
Infliximab	Henoch-Schonlein purpura	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	11	382	22491	2983271	1.815	1.093	2.874	2.145	6.524	2.146	0.011	1.59511007	0.59608547
Infliximab	Hepaplastin decreased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	12	22501	2983641	1.245	0.287	3.907	9.023	6.798	9.023	0.009	0.85518395	0.21913553
Infliximab	Hepatic cancer metastatic	Hepatic neoplasms malignant	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	1	50	22501	2983603	0.736	0.17	2.298	1.051	0.002	1.051	0.96	0.52263848	-0.3065252
Infliximab	Hepatic cirrhosis	Hepatic fibrosis and cirrhosis	Hepatic and hepatobiliary disorders	Hepat	1968-2006	31	3148	22471	2980505	0.949	0.702	1.261	0.966	0.036	0.966	0.849	0.3556144	-0.0523465
Infliximab	Hepatic congestion	Hepatobiliary signs and symptoms	Hepatic and hepatobiliary disorders	Hepat	1968-2006	10	556	22492	2983097	1.078	0.633	1.742	1.165	0.225	1.165	0.636	1.05966943	0.07510747
Infliximab	Hepatic cyst	Hepatobiliary neoplasms benign	Hepatobiliary neoplasms	Hepat	1968-2006	13	474	22489	2983179	1.585	0.993	2.426	1.788	4.323	1.789	0.038	1.58049982	0.46058441
Infliximab	Hepatic encephalopathy	Encephalopathies toxic and metabolic	Encephalopathies	Nerv	1968-2006	12	1732	22490	2981921	0.677	0.416	1.053	0.687	1.688	0.686	0.194	-0.1241846	-0.390084
Infliximab	Hepatic enzyme abnormal	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	158	22501	2983495	0.423	0.098	1.321	0.399	0.896	0.399	0.344	-0.1419547	-0.8603831
Infliximab	Hepatic enzyme increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	54	3285	22448	2980368	0.897	0.714	1.114	0.903	0.554	0.903	0.457	1.06885507	-0.1086994
Infliximab	Hepatic failure	Hepatic failure and associated disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	75	9882	22427	2973771	0.664	0.548	0.8	0.662	12.884	0.66	0.0003313	-0.0066987	-0.4094731
Infliximab	Hepatic fibrosis	Hepatic fibrosis and cirrhosis	Hepatic and hepatobiliary disorders	Hepat	1968-2006	15	806	22487	2982847	1.186	0.768	1.768	1.262	0.795	1.263	0.373	1.15174812	0.1705863
Infliximab	Hepatic function abnormal	Hepatic enzymes and function abnormalities	Hepatic and hepatobiliary disorders	Hepat	1968-2006	41	29283	22461	2954370	0.446	0.344	0.572	0.441	28.91	0.44	7.581e-8	-2.4173798	-0.8074363
Infliximab	Hepatic haematoma	Abdominal injuries NEC	Injuries NEC	Inj&P	1968-2006	1	61	22501	2983592	0.705	0.163	2.202	0.96	0.002	0.96	0.967	0.43912725	-0.3495575
Infliximab	Hepatic haemorrhage	Hepatic vascular disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	1	178	22501	2983475	0.395	0.091	1.232	0.358	1.122	0.358	0.29	-0.2373539	-0.9288695
Infliximab	Hepatic infarction	Hepatic vascular disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	2	154	22500	2983499	0.908	0.294	2.277	1.216	0.074	1.216	0.785	0.45787792	-0.0965109
Infliximab	Hepatic lesion	Hepatic and hepatobiliary disorders NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	9	228	22493	2983425	1.736	0.991	2.87	2.126	5.055	2.126	0.025	1.8390001	0.55158362
Infliximab	Hepatic mass	Hepatic and hepatobiliary disorders NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	3	75	22499	2983578	1.346	0.523	2.975	2.085	1.549	2.085	0.213	1.32568396	0.29713723
Infliximab	Hepatic necrosis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	24	3341	22478	2980312	0.907	0.644	1.25	0.925	0.142	0.925	0.707	-0.0794365	-0.0976128
Infliximab	Hepatic neoplasm	Hepatobiliary neoplasms malignancy unspecified	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	6	447	22496	2983206	1.027	0.518	1.87	1.153	0.12	1.153	0.729	0.66180084	0.02664193
Infliximab	Hepatic neoplasm malignant	Hepatic neoplasms malignant	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	35	1530	22467	2982123	2.331	1.756	3.047	2.563	31.619	2.565	1.876e-8	1.48994149	0.84629736
Infliximab	Hepatic steatosis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	58	4355	22444	2979298	1.058	0.849	1.305	1.072	0.278	1.073	0.598	0.78084823	0.05638033
Infliximab	Hepatic trauma	Abdominal injuries NEC	Injuries NEC	Inj&P	1968-2006	3	432	22499	2983221	0.445	0.173	0.984	0.437	2.136	0.437	0.144	-0.1005832	-0.809681
Infliximab	Hepatic vein thrombosis	Hepatic vascular disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	2	43	22500	2983610	1.482	0.48	3.722	3.52	3.48	3.52	0.062	1.15527573	0.39339253
Infliximab	Hepatitis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	71	15847	22431	2967806	0.727	0.596	0.879	0.725	7.309	0.724	0.007	-0.7573031	-0.3188288
Infliximab	Hepatitis A	Hepatitis viral infections	Viral infectious disorders	Infec	1968-2006	1	391	22501	2983262	0.289	0.067	0.903	0.24	2.422	0.24	0.12	-0.9871133	-1.2413286
Infliximab	Hepatitis A antibody positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	166	22500	2983487	0.805	0.261	2.019	0.998	0	0.998	0.997	0.39929635	-0.216913
Infliximab	Hepatitis B	Hepatitis viral infections	Viral infectious disorders	Infec	1968-2006	21	1022	22481	2982631	1.345	0.931	1.891	1.425	2.577	1.425	0.108	1.30941805	0.29639401
Infliximab	Hepatitis B antibody positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	177	22500	2983476	0.847	0.274	2.122	1.08	0.012	1.08	0.914	0.34760889	-0.1660546
Infliximab	Hepatitis B core antigen	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	0	22501	2983653	1.344	0.308	4.254	1075.473	51.196	1083.041	8.358e-13	0.97840063	0.29565024
Infliximab	Hepatitis B surface antigen positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	273	22500	2983380	0.911	0.295	2.284	1.223	0.079	1.223	0.779	-0.0388141	-0.0932124
Infliximab	Hepatitis B virus	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	136	22501	2983517	0.367	0.085	1.145	0.329	1.387	0.329	0.239	-0.0291742	-1.0023934
Infliximab	Hepatitis C	Hepatitis viral infections	Viral infectious disorders	Infec	1968-2006	13	2412	22489	2981241	0.462	0.29	0.707	0.457	8.31	0.456	0.004	-0.4640642	-0.7721904
Infliximab	Hepatitis C antibody positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	3	220	22499	2983433	0.895	0.348	1.977	1.07	0.013	1.07	0.908	0.57263381	-0.1109316
Infliximab	Hepatitis C positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	117	22501	2983536	0.454	0.105	1.416	0.446	0.695	0.446	0.405	0.0758668	-0.7896581
Infliximab	Hepatitis acute	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	8	742	22494	2982911	0.527	0.291	0.895	0.527	3.364	0.527	0.067	0.433208	-0.6405547
Infliximab	Hepatitis alcoholic	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	9	66	22493	2983587	4.146	2.344	7.008	8.862	50.952	8.871	9.468e-13	2.66821549	1.42214401
Infliximab	Hepatitis cholestatic	Cholestasis and jaundice	Hepatic and hepatobiliary disorders	Hepat	1968-2006	7	1506	22495	2982147	0.351	0.186	0.615	0.34	8.868	0.34	0.003	-0.6351147	-1.0469691
Infliximab	Hepatitis chronic active	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	3	135	22499	2983518	1.155	0.449	2.554	1.578	0.615	1.578	0.433	0.96550405	0.14410034
Infliximab	Hepatitis fulminant	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	5	786	22497	2982867	0.451	0.214	0.862	0.445	3.405	0.445	0.065	-0.2172118	-0.7962879
Infliximab	Hepatitis infectious	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	33	22501	2983620	1.01	0.234	3.153	2.677	0.94	2.677	0.332	0.66203088	0.00995033
Infliximab	Hepatitis toxic	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	6	342	22496	2983311	0.908	0.458	1.654	0.992	0	0.992	0.985	0.94639573	-0.0965109
Infliximab	Hepatitis viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	3	281	22499	2983372	0.744	0.289	1.644	0.83	0.102	0.83	0.749	0.34478654	-0.2957142
Infliximab	Hepato-lenticular degeneration	Central nervous system disorders congenital NEC	Neurological disorders congenital	Cong	1968-2006	1	36	22501	2983617	0.927	0.214	2.893	1.954	0.426	1.954	0.514	0.63643321	-0.0758017
Infliximab	Hepatobiliary disease	Hepatic and hepatobiliary disorders NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	2	31	22500	2983622	1.411	0.457	3.54	3.172	2.687	3.172	0.101	1.25562796	0.34429867
Infliximab	Hepatoblastoma	Hepatoblastomas	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	2	34	22500	2983619	1.645	0.532	4.136	4.837	6.022	4.837	0.014	1.22987801	0.49774038
Infliximab	Hepatocellular damage	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	25	8948	22477	2974705	0.264	0.188	0.361	0.257	53.797	0.256	2.223e-13	-1.4057055	-1.3318062
Infliximab	Hepatomegaly	Hepatobiliary signs and symptoms	Hepatic and hepatobiliary disorders	Hepat	1968-2006	41	4378	22461	2979275	0.898	0.691	1.151	0.907	0.379	0.907	0.538	0.28860908	-0.1075852
Infliximab	Hepatorenal failure	Hepatic failure and associated disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	3	227	22499	2983426	0.8	0.311	1.768	0.916	0.023	0.916	0.879	0.54458456	-0.2231436
Infliximab	Hepatorenal syndrome	Hepatic failure and associated disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	10	1256	22492	2982397	1.56	0.916	2.52	1.813	3.485	1.814	0.062	0.05891398	0.44468582
Infliximab	Hepatosplenomegaly	Hepatobiliary signs and symptoms	Hepatic and hepatobiliary disorders	Hepat	1968-2006	29	1061	22473	2982592	2.314	1.694	3.101	2.585	26.488	2.588	2.652e-7	1.70034949	0.83897763
Infliximab	Hepatotoxicity	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	25	2149	22477	2981504	0.8	0.572	1.096	0.809	1.099	0.809	0.294	0.57810926	-0.2231436
Infliximab	Hernia	Hernias NEC	General system disorders NEC	Genrl	1968-2006	11	1415	22491	2982238	0.939	0.565	1.486	0.988	0.002	0.988	0.968	0.02820596	-0.0629398
Infliximab	Hernia congenital	Gastrointestinal tract disorders congenital NEC	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	31	22501	2983622	0.921	0.213	2.875	1.86	0.401	1.86	0.527	0.67935182	-0.0822952
Infliximab	Hernia hiatus repair	Diaphragmatic therapeutic procedures	Respiratory tract therapeutic procedures	Surg	1968-2006	1	26	22501	2983627	1.13	0.261	3.536	4.457	2.494	4.457	0.114	0.72358631	0.12221763
Infliximab	Hernia obstructive	Hernias NEC	General system disorders NEC	Genrl	1968-2006	2	1	22500	2983652	2.375	0.714	7.038	69.087	74.925	69.087	4.889e-18	1.54208236	0.86499744
Infliximab	Hernia pain	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	1	12	22501	2983641	1.084	0.251	3.388	3.609	1.744	3.609	0.187	0.85518395	0.0806579
Infliximab	Hernia repair	Hernia repairs	Gastrointestinal therapeutic procedures	Surg	1968-2006	7	244	22495	2983409	1.837	0.974	3.22	2.422	5.565	2.422	0.018	1.4635681	0.60813381
Infliximab	Herpes oesophagitis	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	4	21	22498	2983632	2.783	1.207	5.742	9.236	23.512	9.236	1.242e-6	2.06359527	1.02352948
Infliximab	Herpes ophthalmic	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	2	17	22500	2983636	1.764	0.57	4.448	7.12	9.008	7.12	0.003	1.38227191	0.56758396
Infliximab	Herpes simplex	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	47	3530	22455	2980123	0.899	0.704	1.134	0.907	0.445	0.906	0.505	0.77670307	-0.1064722
Infliximab	Herpes simplex DNA test positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	1	22501	2983652	1.328	0.305	4.195	86.049	19.345	86.049	0.00001091	0.967721	0.28367405
Infliximab	Herpes simplex serology	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	9	22500	2983644	1.793	0.579	4.525	8.134	9.985	8.137	0.002	1.45996566	0.58389019
Infliximab	Herpes simplex serology positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	35	22500	2983618	1.416	0.459	3.553	3.221	2.736	3.222	0.098	1.22139582	0.347836
Infliximab	Herpes virus infection	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	17	550	22485	2983103	1.86	1.237	2.71	2.095	9.348	2.096	0.002	1.76810437	0.62057649
Infliximab	Herpes zoster	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	182	3061	22320	2980592	4.499	3.977	5.073	5.031	528.639	5.065	0	2.84374618	1.50385515
Infliximab	Herpes zoster infection neurological	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	1	9	22501	2983644	1.177	0.272	3.686	6.001	3.692	6.001	0.055	0.88501574	0.16296883
Infliximab	Herpes zoster ophthalmic	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	11	52	22491	2983601	6.522	3.536	13.796	14.572	110.825	14.589	6.465e-26	3.01673371	1.87518108
Infliximab	Herpetic stomatitis	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	3	25	22499	2983628	2.052	0.796	4.554	5.763	9.73	5.764	0.002	1.71463043	0.71881493
Infliximab	Hiatus hernia	Diaphragmatic hernias	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	29	1719	22473	2981934	1.102	0.807	1.477	1.134	0.447	1.135	0.504	1.07920178	0.09712671
Infliximab	Hiccups	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	3	1687	22499	2981966	0.285	0.111	0.631	0.265	6.076	0.264	0.014	-1.7825017	-1.2552661
Infliximab	High density lipoprotein decreased	Cholesterol analyses	Lipid analyses	Inv	1968-2006	2	1197	22500	2982456	0.22	0.071	0.551	0.192	6.824	0.192	0.009	-1.7447552	-1.5141277
Infliximab	High density lipoprotein increased	Cholesterol analyses	Lipid analyses	Inv	1968-2006	1	138	22501	2983515	0.494	0.114	1.542	0.503	0.48	0.503	0.488	-0.0397991	-0.7052198
Infliximab	Hilar lymphadenopathy	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	13	132	22489	2983521	4.158	2.597	6.414	6.832	55.696	6.836	8.459e-14	2.73614572	1.42503419
Infliximab	Hip arthroplasty	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	30	643	22472	2983010	2.255	1.66	3.009	2.511	25.608	2.513	4.184e-7	2.34906615	0.81314997
Infliximab	Hip deformity	Trunk deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	3	8	22499	2983645	2.903	1.076	7.193	29.659	46.567	29.659	8.856e-12	1.8750032	1.06574469
Infliximab	Hip fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	51	1785	22451	2981868	1.54	1.218	1.925	1.607	11.092	1.609	0.001	1.80677543	0.43178242
Infliximab	Hip surgery	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	9	98	22493	2983555	2.937	1.675	4.862	4.716	22.746	4.719	1.849e-6	2.46229848	1.07738865
Infliximab	Hip swelling	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	24	22501	2983629	0.924	0.214	2.884	1.918	0.415	1.918	0.52	0.74166694	-0.0790432
Infliximab	Hirsutism	Hypertrichoses	Skin appendage conditions	Skin	1968-2006	2	3986	22500	2979667	0.41	0.133	1.027	0.396	1.846	0.396	0.174	-3.3750691	-0.8915981
Infliximab	Histiocytosis haematophagic	Histiocytoses	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	23	282	22479	2983371	3.524	2.481	4.89	4.447	55.936	4.453	7.486e-14	2.85896076	1.25959671
Infliximab	Histone antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	6	14	22496	2983639	4.573	2.142	11.57	16.482	68.223	16.485	1.46e-16	2.59524057	1.52016944
Infliximab	Histoplasmosis	Histoplasma infections	Fungal infectious disorders	Infec	1968-2006	112	71	22390	2983582	29.285	25	34.131	95.048	3187.289	95.545	0	5.56451058	3.37707544
Infliximab	Histoplasmosis cutaneous	Histoplasma infections	Fungal infectious disorders	Infec	1968-2006	2	0	22500	2983653	2.284	0.702	6.311	1790.48	85.144	1803.157	2.775e-20	1.55268351	0.82592829
Infliximab	Histoplasmosis disseminated	Histoplasma infections	Fungal infectious disorders	Infec	1968-2006	59	42	22443	2983611	26.867	21.569	33.146	84.662	1548.151	85.124	0	5.08370869	3.29089877
Infliximab	Hodgkins disease	Hodgkins disease NEC	Lymphomas Hodgkins disease	Neopl	1968-2006	76	239	22426	2983414	13.292	10.849	16.078	19.501	906.436	19.569	0	4.50827393	2.58716235
Infliximab	Hodgkins disease lymphocyte predominance type stage unspecified	Hodgkins disease lymphocyte predominance type	Lymphomas Hodgkins disease	Neopl	1968-2006	1	2	22501	2983651	1.338	0.307	4.23	70.591	22.452	70.591	2.154e-6	0.95711984	0.29117596
Infliximab	Hodgkins disease mixed cellularity stage IV	Hodgkins disease mixed cellularity type	Lymphomas Hodgkins disease	Neopl	1968-2006	1	2	22501	2983651	1.274	0.294	4.004	17.774	9.337	17.774	0.002	0.95711984	0.24216156
Infliximab	Hodgkins disease mixed cellularity stage unspecified	Hodgkins disease mixed cellularity type	Lymphomas Hodgkins disease	Neopl	1968-2006	2	10	22500	2983643	1.979	0.636	5.048	17.783	19.255	17.783	0.00001144	1.45002205	0.68259167
Infliximab	Hodgkins disease nodular sclerosis stage I site unspecified	Hodgkins disease nodular sclerosis type	Lymphomas Hodgkins disease	Neopl	1968-2006	2	0	22500	2983653	2.469	0.724	8.639	1808.702	132.659	1821.494	1.073e-30	1.55268351	0.90381321
Infliximab	Hodgkins disease nodular sclerosis stage III	Hodgkins disease nodular sclerosis type	Lymphomas Hodgkins disease	Neopl	1968-2006	4	5	22498	2983648	5.26	1.688	29.329	79.624	101.357	79.624	7.682e-24	2.21702652	1.66013103
Infliximab	Hodgkins disease nodular sclerosis stage unspecified	Hodgkins disease nodular sclerosis type	Lymphomas Hodgkins disease	Neopl	1968-2006	5	20	22497	2983633	4.16	1.829	11.265	19.002	62.625	19.007	2.5e-15	2.32662975	1.42551507
Infliximab	Hodgkins disease recurrent	Hodgkins disease NEC	Lymphomas Hodgkins disease	Neopl	1968-2006	1	7	22501	2983646	1.147	0.265	3.587	5.302	2.873	5.302	0.09	0.90525186	0.13714984
Infliximab	Hodgkins disease stage II	Hodgkins disease NEC	Lymphomas Hodgkins disease	Neopl	1968-2006	5	2	22497	2983651	15.452	2.936	50.749	315.776	179.16	315.776	7.393e-41	2.50043997	2.73773844
Infliximab	Hodgkins disease stage III	Hodgkins disease NEC	Lymphomas Hodgkins disease	Neopl	1968-2006	4	3	22498	2983650	4.465	1.606	21.917	50.101	84.099	50.125	4.706e-20	2.23740554	1.49626921
Infliximab	Hodgkins disease stage IV	Hodgkins disease NEC	Lymphomas Hodgkins disease	Neopl	1968-2006	1	5	22501	2983648	1.251	0.289	3.928	9.858	7.27	9.858	0.007	0.92577585	0.22394323
Infliximab	Homicide	Criminal activity	Legal issues	SocCi	1968-2006	1	537	22501	2983116	0.167	0.039	0.524	0.125	6.174	0.125	0.013	-1.3408237	-1.7897615
Infliximab	Hordeolum	Eye and eyelid infections	Infections - pathogen class unspecified	Infec	1968-2006	3	90	22499	2983563	1.47	0.571	3.251	2.424	2.378	2.424	0.123	1.22686636	0.3852624
Infliximab	Hormone level abnormal	Endocrine analyses and imaging NEC	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	1407	22501	2982246	0.295	0.068	0.92	0.241	2.327	0.241	0.127	-2.5400046	-1.2207799
Infliximab	Hospitalisation	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	50	447	22452	2983206	4.415	3.482	5.535	5.445	156.325	5.462	7.187e-36	3.42251791	1.48500783
Infliximab	Hot flush	Peripheral vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	45	3803	22457	2979850	0.854	0.665	1.083	0.86	1.007	0.86	0.316	0.61347451	-0.1578241
Infliximab	Human bite	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	19	22501	2983634	1.014	0.234	3.167	2.727	0.98	2.727	0.322	0.78788532	0.01390291
Infliximab	Human ehrlichiosis	Rickettsial infectious disorders NEC	Rickettsial infectious disorders	Infec	1968-2006	1	10	22501	2983643	1.157	0.267	3.621	5.369	3.126	5.369	0.077	0.87500312	0.14583045
Infliximab	Human papilloma virus test positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	11	22501	2983642	1.15	0.266	3.597	5.405	2.938	5.405	0.087	0.86505951	0.13976194
Infliximab	Humerus fracture	Upper limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	19	325	22483	2983328	2.799	1.902	4.002	3.457	30.224	3.459	3.85e-8	2.47300805	1.02926221
Infliximab	Hunger	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	642	22501	2983011	0.136	0.031	0.426	0.098	8.26	0.098	0.004	-1.5504453	-1.9951004
Infliximab	Hydrocele	Male reproductive tract disorders congenital	Reproductive tract and breast disorders congenital	Cong	1968-2006	3	161	22499	2983492	1.103	0.429	2.438	1.458	0.427	1.458	0.513	0.83359826	0.09803374
Infliximab	Hydrocephalus	Hydrocephalic conditions	Increased intracranial pressure and hydrocephalus	Nerv	1968-2006	21	984	22481	2982669	1.716	1.188	2.413	1.879	8.228	1.88	0.004	1.35679953	0.539996
Infliximab	Hydrometra	Reproductive tract signs and symptoms NEC	Reproductive tract disorders NEC	Repro	1968-2006	1	11	22501	2983642	1.118	0.258	3.496	4.462	2.286	4.462	0.131	0.86505951	0.11154137
Infliximab	Hydronephrosis	Renal obstructive disorders	Renal disorders (excl nephropathies)	Renal	1968-2006	26	1149	22476	2982504	1.731	1.245	2.356	1.875	10.038	1.876	0.002	1.45141155	0.54869928
Infliximab	Hydrothorax	Pneumothorax and pleural effusions NEC	Pleural disorders	Resp	1968-2006	2	45	22500	2983608	1.244	0.403	3.12	2.267	1.341	2.267	0.247	1.13920853	0.21833199
Infliximab	Hydroureter	Ureteric disorders NEC	Ureteric disorders	Renal	1968-2006	3	64	22499	2983589	1.993	0.773	4.419	5.042	8.577	5.042	0.003	1.40270905	0.68964104
Infliximab	Hyperaemia	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	6	228	22496	2983425	1.489	0.752	2.712	1.877	2.362	1.877	0.124	1.33615371	0.39810475
Infliximab	Hyperaesthesia	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	5	1655	22497	2981998	0.406	0.193	0.776	0.396	4.544	0.395	0.033	-1.1735926	-0.9014021
Infliximab	Hyperbilirubinaemia	Cholestasis and jaundice	Hepatic and hepatobiliary disorders	Hepat	1968-2006	5	7767	22497	2975886	0.301	0.143	0.575	0.288	8.789	0.288	0.003	-3.3165722	-1.200645
Infliximab	Hyperbilirubinaemia neonatal	Cholestasis and jaundice	Hepatic and hepatobiliary disorders	Hepat	1968-2006	1	95	22501	2983558	0.629	0.145	1.964	0.763	0.072	0.763	0.789	0.20788933	-0.463624
Infliximab	Hypercalcaemia	Calcium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	14	2142	22488	2981511	0.71	0.452	1.071	0.72	1.5	0.72	0.221	-0.2041386	-0.3424903
Infliximab	Hypercalciuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	1	72	22501	2983581	0.859	0.199	2.682	1.525	0.181	1.525	0.67	0.36018617	-0.1519864
Infliximab	Hypercapnia	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	6	449	22496	2983204	0.926	0.468	1.687	1.016	0.002	1.016	0.969	0.65688936	-0.076881
Infliximab	Hypercatabolism	Metabolic disorders NEC	Metabolism disorders NEC	Metab	1968-2006	1	8	22501	2983645	1.234	0.285	3.869	9.137	6.049	9.139	0.014	0.89509832	0.21026093
Infliximab	Hyperchlorhydria	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	2	206	22500	2983447	0.63	0.204	1.58	0.691	0.27	0.691	0.604	0.21960282	-0.4620355
Infliximab	Hypercholesterolaemia	Elevated cholesterol	Lipid metabolism disorders	Metab	1968-2006	15	6186	22487	2977467	0.569	0.368	0.848	0.568	4.827	0.568	0.028	-1.5811469	-0.5638748
Infliximab	Hyperchromasia	Red blood cell abnormal findings NEC	Red blood cell disorders	Blood	1968-2006	1	2	22501	2983651	1.261	0.291	3.959	14.683	8.086	14.688	0.004	0.95711984	0.23190506
Infliximab	Hypercoagulation	Coagulopathies	Coagulopathies and bleeding diatheses (excl thrombocytopenic)	Blood	1968-2006	6	197	22496	2983456	1.424	0.719	2.592	1.784	1.914	1.784	0.167	1.46327193	0.35346981
Infliximab	Hyperemesis gravidarum	Maternal complications of pregnancy NEC	Maternal complications of pregnancy	Preg	1968-2006	1	35	22501	2983618	0.875	0.203	2.733	1.637	0.23	1.637	0.631	0.64491541	-0.1335314
Infliximab	Hypereosinophilic syndrome	Eosinophilic disorders	White blood cell disorders	Blood	1968-2006	3	56	22499	2983597	1.591	0.618	3.52	2.823	3.387	2.823	0.066	1.46142821	0.46436275
Infliximab	Hypergammaglobulinaemia	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	4	455	22498	2983198	1.037	0.453	2.107	1.245	0.187	1.245	0.666	0.16168869	0.03633193
Infliximab	Hypergammaglobulinaemia benign monoclonal	Plasma cell neoplasms NEC	Plasma cell neoplasms	Neopl	1968-2006	5	57	22497	2983596	2.57	1.217	4.926	5.23	15.521	5.232	0.00008159	2.02409037	0.9439059
Infliximab	Hyperglycaemia	Hyperglycaemic conditions NEC	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	27	22521	22475	2961132	0.326	0.236	0.441	0.319	38.996	0.318	4.247e-10	-2.6219264	-1.1208579
Infliximab	Hyperhidrosis	Apocrine and eccrine gland disorders	Skin appendage conditions	Skin	1968-2006	256	30437	22246	2953216	1.03	0.929	1.14	1.034	0.276	1.034	0.6	0.12982739	0.0295588
Infliximab	Hyperkalaemia	Potassium imbalance	Electrolyte and fluid balance conditions	Metab	1968-2006	14	8517	22488	2975136	0.205	0.131	0.309	0.197	45.668	0.197	1.401e-11	-2.1272661	-1.5847453
Infliximab	Hyperkeratosis	Hyperkeratoses	Cornification and dystrophic skin disorders	Skin	1968-2006	19	434	22483	2983219	2.776	1.886	3.969	3.4	29.571	3.402	5.389e-8	2.17637888	1.02101104
Infliximab	Hyperkinetic heart syndrome	Cardiac disorders NEC	Cardiac disorder signs and symptoms	Card	1968-2006	1	17	22501	2983636	1.176	0.272	3.681	5.991	3.62	5.991	0.057	0.80679534	0.16211885
Infliximab	Hyperlactacidaemia	Metabolic acidoses (excl diabetic acidoses)	Acid-base disorders	Metab	1968-2006	2	240	22500	2983413	0.426	0.138	1.068	0.412	1.653	0.412	0.199	0.08269549	-0.8533159
Infliximab	Hyperlipidaemia	Hyperlipidaemias NEC	Lipid metabolism disorders	Metab	1968-2006	9	6384	22493	2977269	0.306	0.174	0.505	0.296	14.982	0.295	0.0001086	-2.3023929	-1.1841702
Infliximab	Hypermetropia	Refractive and accommodative disorders	Vision disorders	Eye	1968-2006	1	95	22501	2983558	0.593	0.137	1.85	0.685	0.143	0.685	0.706	0.20788933	-0.5225609
Infliximab	Hypernatraemia	Sodium imbalance	Electrolyte and fluid balance conditions	Metab	1968-2006	2	979	22500	2982674	0.28	0.091	0.703	0.25	4.435	0.25	0.035	-1.486931	-1.2729657
Infliximab	Hyperoxaluria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	1	14	22501	2983639	1.152	0.266	3.605	5.11	2.973	5.111	0.085	0.83563334	0.14149956
Infliximab	Hyperparathyroidism	Hyperparathyroid disorders	Parathyroid gland disorders	Endo	1968-2006	4	227	22498	2983426	0.892	0.389	1.812	1.016	0.001	1.016	0.975	0.86255007	-0.1142891
Infliximab	Hyperphagia	Appetite disorders	Appetite and general nutritional disorders	Metab	1968-2006	1	292	22501	2983361	0.274	0.063	0.855	0.222	2.712	0.222	0.1	-0.6859811	-1.2946272
Infliximab	Hyperplasia	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	8	361	22494	2983292	1.485	0.82	2.521	1.767	2.542	1.767	0.111	1.24738052	0.39541477
Infliximab	Hyperpyrexia	Febrile disorders	Body temperature conditions	Genrl	1968-2006	17	709	22485	2982944	1.327	0.882	1.934	1.421	2.065	1.422	0.151	1.47295143	0.28292076
Infliximab	Hyperreflexia	Abnormal reflexes	Neurological disorders NEC	Nerv	1968-2006	5	964	22497	2982689	0.476	0.226	0.909	0.472	2.905	0.472	0.088	-0.4713073	-0.7423374
Infliximab	Hypersensitivity	Allergic conditions NEC	Allergic conditions	Immun	1968-2006	332	37888	22170	2945765	1.469	1.341	1.607	1.493	52.452	1.501	4.408e-13	0.18475038	0.3845819
Infliximab	Hypersomnia	Narcolepsy and hypersomnia	Sleep disturbances (incl subtypes)	Nerv	1968-2006	9	1703	22493	2981950	0.316	0.18	0.522	0.305	14.082	0.305	0.000175	-0.4778822	-1.1520131
Infliximab	Hypertension	Vascular hypertensive disorders NEC	Vascular hypertensive disorders	Vasc	1968-2006	291	46137	22211	2937516	0.841	0.763	0.925	0.839	8.977	0.837	0.003	-0.2886276	-0.1731636
Infliximab	Hypertensive cardiomegaly	Cardiac hypertensive complications	Cardiac disorder signs and symptoms	Card	1968-2006	1	13	22501	2983640	1.141	0.264	3.57	5.114	2.74	5.114	0.098	0.84537553	0.13190507
Infliximab	Hypertensive crisis	Accelerated and malignant hypertension	Vascular hypertensive disorders	Vasc	1968-2006	19	1363	22483	2982290	0.982	0.667	1.404	1.014	0.004	1.014	0.952	0.8064835	-0.018164
Infliximab	Hypertensive heart disease	Cardiac hypertensive complications	Cardiac disorder signs and symptoms	Card	1968-2006	8	513	22494	2983140	1.078	0.595	1.83	1.188	0.226	1.188	0.634	0.86610111	0.07510747
Infliximab	Hypertensive nephropathy	Renal hypertension and related conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	51	22501	2983602	0.887	0.205	2.768	1.688	0.265	1.688	0.607	0.51484364	-0.1199103
Infliximab	Hyperthermia	Body temperature altered	Body temperature conditions	Genrl	1968-2006	4	495	22498	2983158	0.515	0.225	1.046	0.518	1.763	0.518	0.184	0.06743371	-0.6635884
Infliximab	Hyperthermia malignant	Body temperature altered	Body temperature conditions	Genrl	1968-2006	2	969	22500	2982684	0.379	0.123	0.95	0.356	2.279	0.356	0.131	-1.4739241	-0.9702191
Infliximab	Hyperthyroidism	Thyroid hyperfunction disorders	Thyroid gland disorders	Endo	1968-2006	20	2278	22482	2981375	0.898	0.617	1.273	0.92	0.137	0.92	0.711	0.1944118	-0.1075852
Infliximab	Hypertonia	Muscle tone abnormal	Neuromuscular disorders	Nerv	1968-2006	4	12051	22498	2971602	0.179	0.078	0.363	0.164	17.108	0.164	0.00003532	-4.2062708	-1.7203695
Infliximab	Hypertonic bladder	Myoneurogenic bladder disorders	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	2	226	22500	2983427	0.574	0.186	1.439	0.608	0.498	0.608	0.48	0.13750535	-0.5551259
Infliximab	Hypertriglyceridaemia	Elevated triglycerides	Lipid metabolism disorders	Metab	1968-2006	10	1805	22492	2981848	0.468	0.275	0.756	0.464	6.153	0.463	0.013	-0.4187763	-0.759287
Infliximab	Hypertrophic cardiomyopathy	Cardiomyopathies	Myocardial disorders	Card	1968-2006	4	271	22498	2983382	0.919	0.401	1.867	1.057	0.012	1.057	0.913	0.69815217	-0.0844692
Infliximab	Hypertrophy	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	5	348	22497	2983305	1.191	0.565	2.274	1.441	0.646	1.441	0.421	0.70909947	0.17479329
Infliximab	Hypertrophy breast				1968-2006	2	3108	22500	2980545	0.136	0.044	0.34	0.113	13.953	0.113	0.0001874	-3.029035	-1.9951004
Infliximab	Hyperuricaemia	Purine metabolism disorders NEC	Purine and pyrimidine metabolism disorders	Metab	1968-2006	2	1352	22500	2982301	0.378	0.122	0.947	0.356	2.295	0.356	0.13	-1.9035736	-0.9728611
Infliximab	Hyperventilation	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	13	3635	22489	2980018	0.633	0.397	0.968	0.638	2.643	0.637	0.104	-1.0282991	-0.4572849
Infliximab	Hypervolaemia	Total fluid volume increased	Electrolyte and fluid balance conditions	Metab	1968-2006	1	237	22501	2983416	0.551	0.127	1.719	0.606	0.259	0.606	0.611	-0.4868186	-0.5960205
Infliximab	Hypoacusis	Hearing losses	Hearing disorders	Ear	1968-2006	14	705	22488	2982948	0.983	0.627	1.484	1.027	0.01	1.027	0.92	1.22171567	-0.0171462
Infliximab	Hypoaesthesia	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	249	18779	22253	2964874	1.169	1.052	1.295	1.177	6.528	1.18	0.011	0.78162861	0.15614868
Infliximab	Hypoaesthesia facial	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	128	22501	2983525	0.527	0.122	1.645	0.564	0.34	0.563	0.56	0.01412534	-0.6405547
Infliximab	Hypoaesthesia oral	Oral soft tissue signs and symptoms	Oral soft tissue conditions	Gastr	1968-2006	15	1314	22487	2982339	0.73	0.473	1.088	0.741	1.333	0.741	0.248	0.5359332	-0.3147107
Infliximab	Hypoalbuminaemia	Protein metabolism disorders NEC	Protein and amino acid metabolism disorders NEC	Metab	1968-2006	17	519	22485	2983134	1.684	1.119	2.453	1.869	6.57	1.87	0.01	1.83341121	0.52117192
Infliximab	Hypocalcaemia	Calcium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	7	2315	22495	2981338	0.299	0.158	0.523	0.286	12.327	0.286	0.0004466	-1.2120929	-1.2073117
Infliximab	Hypochromic anaemia	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	6	118	22496	2983535	1.75	0.883	3.188	2.383	4.541	2.384	0.033	1.84921868	0.55961579
Infliximab	Hypocomplementaemia	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	2	24	22500	2983629	1.668	0.54	4.197	5.469	6.543	5.469	0.011	1.31756088	0.5116253
Infliximab	Hypogammaglobulinaemia	Primary immunodeficiency syndromes	Immunodeficiency syndromes	Immun	1968-2006	3	200	22499	2983453	1.031	0.401	2.279	1.323	0.224	1.323	0.636	0.65591613	0.03052921
Infliximab	Hypogeusia	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	1	76	22501	2983577	0.637	0.147	1.987	0.783	0.06	0.783	0.806	0.33251843	-0.4509856
Infliximab	Hypoglossal nerve disorder	Hypoglossal nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	11	22501	2983642	1.188	0.274	3.72	5.981	4.012	5.981	0.045	0.86505951	0.17227122
Infliximab	Hypoglycaemia	Hypoglycaemic conditions NEC	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	52	17491	22450	2966162	0.409	0.324	0.51	0.403	45.812	0.401	1.302e-11	-1.3392307	-0.8940401
Infliximab	Hypokalaemia	Potassium imbalance	Electrolyte and fluid balance conditions	Metab	1968-2006	76	10270	22426	2973383	0.886	0.732	1.065	0.889	1.027	0.889	0.311	-0.0425996	-0.1210383
Infliximab	Hypokinesia	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	15	1837	22487	2981816	0.997	0.646	1.486	1.041	0.023	1.041	0.879	0.09463935	-0.0030045
Infliximab	Hypomagnesaemia	Magnesium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	7	666	22495	2982987	0.554	0.294	0.971	0.557	2.421	0.556	0.12	0.39486054	-0.5905906
Infliximab	Hypomania	Mood alterations with manic symptoms	Manic and bipolar mood disorders and disturbances	Psych	1968-2006	1	545	22501	2983108	0.157	0.036	0.492	0.115	6.776	0.115	0.009	-1.3579113	-1.8515095
Infliximab	Hyponatraemia	Sodium imbalance	Electrolyte and fluid balance conditions	Metab	1968-2006	69	13080	22433	2970573	0.583	0.476	0.707	0.578	21.112	0.576	4.331e-6	-0.5234211	-0.5395681
Infliximab	Hypoperfusion	Circulatory collapse and shock	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	2	97	22500	2983556	0.922	0.299	2.312	1.247	0.096	1.247	0.757	0.77412175	-0.0812101
Infliximab	Hypophonesis	Physical examination procedures	Physical examination topics	Inv	1968-2006	2	9	22500	2983644	1.942	0.625	4.937	13.128	16.773	13.129	0.00004213	1.45996566	0.66371837
Infliximab	Hypophosphataemia	Phosphorus metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	5	756	22497	2982897	0.66	0.313	1.261	0.687	0.699	0.687	0.403	-0.1696105	-0.4155154
Infliximab	Hypopnoea	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	1	85	22501	2983568	0.685	0.159	2.139	0.903	0.01	0.903	0.92	0.27214012	-0.3783364
Infliximab	Hypoproteinaemia	Protein metabolism disorders NEC	Protein and amino acid metabolism disorders NEC	Metab	1968-2006	10	1586	22492	2982067	0.778	0.457	1.257	0.805	0.468	0.805	0.494	-0.2466704	-0.2510288
Infliximab	Hyporeflexia	Abnormal reflexes	Neurological disorders NEC	Nerv	1968-2006	8	1337	22494	2982316	0.733	0.404	1.244	0.759	0.602	0.759	0.438	-0.3098492	-0.3106096
Infliximab	Hypospadias	Male reproductive tract disorders congenital	Reproductive tract and breast disorders congenital	Cong	1968-2006	2	326	22500	2983327	0.443	0.144	1.111	0.435	1.459	0.435	0.227	-0.2147956	-0.8141855
Infliximab	Hypotension	Vascular hypotensive disorders	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	442	51480	22060	2932173	1.304	1.205	1.409	1.316	33.207	1.323	8.284e-9	0.14917138	0.26543646
Infliximab	Hypothermia	Body temperature altered	Body temperature conditions	Genrl	1968-2006	11	2435	22491	2981218	0.505	0.304	0.799	0.502	5.371	0.502	0.02	-0.6982605	-0.6831968
Infliximab	Hypothermia neonatal	Neonatal metabolic and endocrine disorders	Neonatal and perinatal conditions	Preg	1968-2006	1	20	22501	2983633	1.05	0.243	3.28	3.105	1.312	3.105	0.252	0.77852244	0.04879016
Infliximab	Hypothyroidism	Thyroid hypofunction disorders	Thyroid gland disorders	Endo	1968-2006	15	3697	22487	2979956	0.421	0.273	0.628	0.416	12.267	0.415	0.0004611	-0.859896	-0.8651224
Infliximab	Hypotonia	Muscle tone abnormal	Neuromuscular disorders	Nerv	1968-2006	7	3018	22495	2980635	0.283	0.15	0.497	0.271	13.599	0.271	0.0002262	-1.5756434	-1.2623084
Infliximab	Hypotonia neonatal	Muscle tone abnormalities	Muscle disorders	Musc	1968-2006	1	480	22501	2983173	0.163	0.038	0.511	0.121	6.417	0.121	0.011	-1.2128407	-1.8140051
Infliximab	Hypotonic urinary bladder	Myoneurogenic bladder disorders	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	1	10	22501	2983643	1.173	0.271	3.67	6.312	3.534	6.312	0.06	0.87500312	0.15956457
Infliximab	Hypotrichosis	Alopecias	Skin appendage conditions	Skin	1968-2006	3	403	22499	2983250	0.381	0.148	0.843	0.365	3.28	0.365	0.07	-0.0250448	-0.9649559
Infliximab	Hypoventilation	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	15	3552	22487	2980101	0.92	0.595	1.37	0.952	0.036	0.952	0.85	-0.8043762	-0.0833816
Infliximab	Hypovolaemia	Total fluid volume decreased	Electrolyte and fluid balance conditions	Metab	1968-2006	23	1541	22479	2982112	1.23	0.866	1.706	1.288	1.432	1.288	0.231	0.90582372	0.20701417
Infliximab	Hypovolaemic shock	Circulatory collapse and shock	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	6	502	22496	2983151	0.772	0.39	1.406	0.819	0.239	0.819	0.625	0.53247621	-0.2587707
Infliximab	Hypoxia	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	138	8653	22364	2975000	1.622	1.407	1.861	1.664	35.196	1.669	2.981e-9	1.04206314	0.48365996
Infliximab	Hypoxic encephalopathy	Encephalopathies NEC	Encephalopathies	Nerv	1968-2006	1	418	22501	2983235	0.196	0.045	0.611	0.147	4.888	0.147	0.027	-1.0593973	-1.6296406
Infliximab	Hysterectomy	Uterine therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	17	807	22485	2982846	1.376	0.915	2.005	1.485	2.571	1.486	0.109	1.31714567	0.31918074
Infliximab	Hysterosalpingo-oophorectomy	Uterine therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	2	7	22500	2983646	1.956	0.629	4.979	14.664	17.701	14.67	0.00002585	1.48006086	0.67090157
Infliximab	IIIrd nerve paralysis	Eye movement disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	2	192	22500	2983461	0.673	0.218	1.688	0.761	0.148	0.761	0.701	0.27998306	-0.3960099
Infliximab	IUCD complication	Device related complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	316	22500	2983337	0.416	0.135	1.042	0.399	1.779	0.399	0.182	-0.1831927	-0.87707
Infliximab	IVth nerve paralysis	Eye movement disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	37	22501	2983616	0.896	0.207	2.798	1.746	0.301	1.746	0.583	0.62800058	-0.1098149
Infliximab	Iatrogenic injury	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	9	684	22493	2982969	0.704	0.402	1.163	0.721	0.949	0.721	0.33	0.68144363	-0.3509769
Infliximab	Ichthyosis	Skin and subcutaneous tissue disorders congenital NEC	Skin and subcutaneous tissue disorders congenital	Cong	1968-2006	1	36	22501	2983617	1.161	0.268	3.632	5.121	3.156	5.121	0.076	0.63643321	0.1492817
Infliximab	Idiopathic capillaritis	Skin vasculitides	Skin vascular abnormalities	Skin	1968-2006	1	15	22501	2983638	1.118	0.258	3.497	4.343	2.28	4.343	0.131	0.82595649	0.11154137
Infliximab	Idiopathic pulmonary fibrosis	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	2	32	22500	2983621	1.575	0.51	3.958	4.555	4.801	4.556	0.028	1.24699348	0.45425527
Infliximab	Idiopathic thrombocytopenic purpura	Thrombocytopenias	Platelet disorders	Blood	1968-2006	10	2967	22492	2980686	0.584	0.343	0.943	0.588	2.868	0.587	0.09	-1.0940947	-0.5378543
Infliximab	Ileal operation	Small intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.327	0.305	4.192	41.681	18.966	41.681	0.00001331	0.967721	0.28292076
Infliximab	Ileal perforation	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	7	59	22495	2983594	3.346	1.767	5.915	7.019	30.561	7.022	3.236e-8	2.40992023	1.2077656
Infliximab	Ileal stenosis	Duodenal and small intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	20	45	22482	2983608	20.349	13.692	29.203	42.177	405.184	42.215	0	3.80948649	3.01303177
Infliximab	Ileal ulcer	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	2	81	22500	2983572	1.22	0.396	3.061	2.195	1.197	2.195	0.274	0.8769495	0.19885086
Infliximab	Ileectomy	Small intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	2	5	22500	2983648	2.07	0.66	5.341	30.382	27.253	30.382	1.785e-7	1.50043989	0.72754861
Infliximab	Ileitis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	6	357	22496	2983296	1.793	0.905	3.266	2.493	4.929	2.494	0.026	0.9021392	0.58389019
Infliximab	Ileostomy	Small intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	5	62	22497	2983591	2.578	1.221	4.943	5.273	15.631	5.274	0.00007699	1.98767187	0.9470139
Infliximab	Ileostomy closure	Small intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.33	0.305	4.202	98.803	20.008	98.803	7.713e-6	0.967721	0.28517894
Infliximab	Ileus	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	34	1654	22468	2981999	1.597	1.198	2.095	1.684	9.105	1.686	0.003	1.34837933	0.46812687
Infliximab	Ileus paralytic	Non-mechanical ileus	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	14	2512	22488	2981141	0.707	0.451	1.067	0.717	1.539	0.717	0.215	-0.4204317	-0.3467246
Infliximab	Iliac artery embolism	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	10	22501	2983643	1.201	0.277	3.763	6.56	4.52	6.56	0.034	0.87500312	0.18315454
Infliximab	Iliac artery thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	74	22501	2983579	0.69	0.16	2.155	0.916	0.007	0.916	0.932	0.34628598	-0.3710637
Infliximab	Ilium fracture	Pelvic fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	1	16	22501	2983637	1.003	0.232	3.131	2.555	0.891	2.555	0.345	0.81634411	0.00299551
Infliximab	Ill-defined disorder	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	4	2805	22498	2980848	0.063	0.027	0.128	0.055	65.267	0.055	6.54e-16	-2.1514181	-2.7646206
Infliximab	Immature respiratory system	Newborn respiratory disorders NEC	Neonatal respiratory disorders	Resp	1968-2006	1	21	22501	2983632	1.018	0.235	3.18	2.657	1.016	2.658	0.314	0.76921993	0.01783992
Infliximab	Immobile	Disability issues	Lifestyle issues	SocCi	1968-2006	8	503	22494	2983150	1.131	0.625	1.921	1.259	0.409	1.259	0.523	0.88831552	0.1231022
Infliximab	Immune complex assay	Immunology analyses NEC	Immunology and allergy investigations	Inv	1968-2006	1	0	22501	2983653	1.371	0.313	4.357	1087.134	81.497	1094.832	1.755e-19	0.97840063	0.3155404
Infliximab	Immune reconstitution syndrome	Immunodeficiency disorders NEC	Immunodeficiency syndromes	Immun	1968-2006	2	336	22500	2983317	0.392	0.127	0.982	0.376	2.089	0.375	0.148	-0.2457213	-0.9364934
Infliximab	Immune system disorder	Immune and associated conditions NEC	Immune disorders NEC	Immun	1968-2006	36	1319	22466	2982334	2.625	1.984	3.419	2.952	43.095	2.955	5.214e-11	1.71996229	0.9650809
Infliximab	Immunoblastic lymphoma	Non-Hodgkins lymphomas unspecified histology aggressive	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	1	1	22501	2983652	1.317	0.303	4.155	31.647	16.278	31.647	0.00005468	0.967721	0.27535642
Infliximab	Immunodeficiency	Immunodeficiency disorders NEC	Immunodeficiency syndromes	Immun	1968-2006	7	178	22495	2983475	1.865	0.989	3.269	2.483	5.869	2.484	0.015	1.735216	0.62326105
Infliximab	Immunodeficiency common variable	Primary immunodeficiency syndromes	Immunodeficiency syndromes	Immun	1968-2006	5	180	22497	2983473	2.521	1.194	4.831	5.025	14.616	5.026	0.0001318	1.32017794	0.92465565
Infliximab	Immunoglobulins abnormal	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	2	53	22500	2983600	1.361	0.441	3.415	2.859	2.224	2.859	0.136	1.07667128	0.30821972
Infliximab	Immunoglobulins decreased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	32	22501	2983621	0.95	0.22	2.966	2.064	0.54	2.064	0.462	0.67066536	-0.0512933
Infliximab	Immunoglobulins increased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	3	59	22499	2983594	1.633	0.634	3.612	2.992	3.776	2.993	0.052	1.43912756	0.49041881
Infliximab	Immunology test abnormal	Immunology analyses NEC	Immunology and allergy investigations	Inv	1968-2006	2	73	22500	2983580	1.138	0.369	2.852	1.844	0.761	1.844	0.383	0.93124866	0.12927234
Infliximab	Immunosuppression	Immunodeficiency disorders NEC	Immunodeficiency syndromes	Immun	1968-2006	67	555	22435	2983098	5.695	4.637	6.942	7.066	300.516	7.089	0	3.57660323	1.7395886
Infliximab	Impaired gastric emptying	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	4	480	22498	2983173	0.494	0.215	1.003	0.495	2.056	0.495	0.152	0.10206202	-0.7052198
Infliximab	Impaired healing	Healing abnormal NEC	Tissue disorders NEC	Genrl	1968-2006	67	2948	22435	2980705	1.643	1.34	1.999	1.707	18.777	1.709	0.00001469	1.51642691	0.49652384
Infliximab	Impaired work ability	Disability issues	Lifestyle issues	SocCi	1968-2006	5	1211	22497	2982442	0.232	0.11	0.444	0.219	14.01	0.218	0.0001819	-0.7630503	-1.4610179
Infliximab	Impatience	Behaviour and socialisation disturbances	Personality disorders and disturbances in behaviour	Psych	1968-2006	1	105	22501	2983548	0.458	0.106	1.429	0.449	0.672	0.449	0.412	0.14637798	-0.7808861
Infliximab	Impetigo	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	2	147	22500	2983506	0.731	0.237	1.833	0.86	0.045	0.86	0.832	0.49318202	-0.3133418
Infliximab	Implant site effusion	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	10	22501	2983643	1.205	0.278	3.776	8.138	4.681	8.14	0.03	0.87500312	0.18647957
Infliximab	Implant site inflammation	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	2	5	22500	2983648	2.008	0.644	5.137	17.074	21.585	17.074	3.385e-6	1.50043989	0.6971392
Infliximab	Implant site oedema	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	2	22501	2983651	1.365	0.311	4.33	63.808	37.939	63.808	7.3e-10	0.95711984	0.31115443
Infliximab	Implant site reaction	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	3	598	22499	2983055	0.379	0.147	0.838	0.361	3.317	0.361	0.069	-0.4702109	-0.9702191
Infliximab	Implantable defibrillator insertion	Cardiac therapeutic procedures NEC	Cardiac therapeutic procedures	Surg	1968-2006	1	42	22501	2983611	0.847	0.196	2.642	1.483	0.149	1.483	0.7	0.58656124	-0.1660546
Infliximab	Impulsive behaviour	Impulse control disorders	Impulse control disorders NEC	Psych	1968-2006	1	459	22501	2983194	0.167	0.038	0.521	0.123	6.227	0.123	0.013	-1.1626735	-1.7897615
Infliximab	In vitro fertilisation	Fertility and fertilisation interventions female	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	7	22501	2983646	1.201	0.277	3.763	7.793	4.535	7.793	0.033	0.90525186	0.18315454
Infliximab	Inappropriate antidiuretic hormone secretion	Posterior pituitary disorders	Hypothalamus and pituitary gland disorders	Endo	1968-2006	12	2797	22490	2980856	0.495	0.304	0.77	0.49	6.267	0.49	0.012	-0.7729028	-0.7031975
Infliximab	Inappropriate schedule of drug administration	Maladministrations	Medication errors	Inj&P	1968-2006	1	370	22501	2983283	0.216	0.05	0.674	0.165	4.177	0.165	0.041	-0.9282775	-1.5324769
Infliximab	Incision site abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	3	19	22499	2983634	2.174	0.842	4.836	6.788	12.438	6.788	0.0004207	1.76922008	0.77656879
Infliximab	Incision site complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	5	186	22497	2983467	1.226	0.581	2.341	1.502	0.796	1.502	0.372	1.29325792	0.20375684
Infliximab	Incisional hernia	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	9	127	22493	2983526	2.895	1.651	4.793	4.571	21.87	4.572	2.918e-6	2.29809775	1.06298511
Infliximab	Incisional hernia gangrenous	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.329	0.305	4.196	98.675	19.459	98.675	0.00001028	0.967721	0.28442678
Infliximab	Incisional hernia repair	Hernia repairs	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	12	22501	2983641	1.162	0.269	3.637	5.628	3.248	5.628	0.072	0.85518395	0.15014266
Infliximab	Incoherent	Speech and language abnormalities	Neurological disorders NEC	Nerv	1968-2006	5	896	22497	2982757	0.296	0.14	0.566	0.281	9.12	0.281	0.003	-0.3794376	-1.2173958
Infliximab	Incontinence	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	7	882	22495	2982771	0.423	0.224	0.74	0.413	5.723	0.413	0.017	0.05243776	-0.8603831
Infliximab	Increased appetite	Appetite disorders	Appetite and general nutritional disorders	Metab	1968-2006	3	3940	22499	2979713	0.119	0.046	0.264	0.104	23.014	0.104	1.608e-6	-2.9441712	-2.1286318
Infliximab	Increased tendency to bruise	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	7	372	22495	2983281	0.984	0.522	1.725	1.077	0.038	1.077	0.845	1.04902727	-0.0161294
Infliximab	Increased upper airway secretion	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	3	401	22499	2983252	0.422	0.164	0.932	0.41	2.509	0.41	0.113	-0.0196865	-0.86275
Infliximab	Induration	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	121	22501	2983532	0.473	0.109	1.475	0.467	0.589	0.467	0.443	0.05310852	-0.7486599
Infliximab	Infantile apnoeic attack	Neonatal hypoxic conditions	Neonatal respiratory disorders	Resp	1968-2006	3	350	22499	2983303	0.503	0.195	1.112	0.506	1.428	0.506	0.232	0.12413627	-0.6871651
Infliximab	Infarction	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	8	732	22494	2982921	0.76	0.419	1.29	0.79	0.437	0.79	0.509	0.44963348	-0.2744368
Infliximab	Infected sebaceous cyst	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	2	12	22500	2983641	1.778	0.575	4.486	7.437	9.478	7.437	0.002	1.43033808	0.57548914
Infliximab	Infected skin ulcer	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	7	141	22495	2983512	1.96	1.039	3.436	2.716	6.92	2.717	0.009	1.9133355	0.67294447
Infliximab	Infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	257	17128	22245	2966525	2.043	1.842	2.261	2.112	143.652	2.125	4.233e-33	0.9572052	0.71441932
Infliximab	Infection in an immunocompromised host	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	15	194	22487	2983459	3.303	2.137	4.927	4.524	37.169	4.527	1.083e-9	2.63042646	1.19483115
Infliximab	Infection masked	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	23	22501	2983630	1.236	0.285	3.878	9.976	6.191	9.976	0.013	0.75079293	0.21188036
Infliximab	Infection parasitic	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	2	81	22500	2983572	1.18	0.382	2.959	1.979	0.97	1.979	0.325	0.8769495	0.16551444
Infliximab	Infection protozoal	Protozoal infections NEC	Protozoal infectious disorders	Infec	1968-2006	2	5	22500	2983648	2.219	0.692	5.946	52.061	46.73	52.092	8.146e-12	1.50043989	0.79705664
Infliximab	Infectious mononucleosis	Epstein-Barr viral infections	Viral infectious disorders	Infec	1968-2006	13	648	22489	2983005	1.34	0.84	2.051	1.467	1.859	1.468	0.173	1.22384842	0.29266961
Infliximab	Infective spondylitis	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	2	10	22500	2983643	2.081	0.663	5.377	24.009	28.104	24.009	1.15e-7	1.45002205	0.73284855
Infliximab	Infective tenosynovitis	Muscle and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	2	7	22500	2983646	2.052	0.655	5.279	17.903	25.219	17.912	5.117e-7	1.48006086	0.71881493
Infliximab	Inferior vena caval occlusion	Site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	34	22500	2983619	1.443	0.468	3.623	3.455	3.047	3.455	0.081	1.22987801	0.36672428
Infliximab	Infertility	Sexual function and fertility disorders NEC	Sexual function and fertility disorders	Repro	1968-2006	3	344	22499	2983309	0.666	0.259	1.472	0.718	0.327	0.718	0.568	0.14203902	-0.4064656
Infliximab	Infertility female	Sexual function and fertility disorders NEC	Sexual function and fertility disorders	Repro	1968-2006	2	1119	22500	2982534	0.636	0.206	1.595	0.703	0.25	0.703	0.617	-1.6577008	-0.4525567
Infliximab	Infestation	Ectoparasitic infestations	Ectoparasitic disorders	Infec	1968-2006	1	12	22501	2983641	1.155	0.267	3.616	5.577	3.086	5.577	0.079	0.85518395	0.14410034
Infliximab	Inflammation	Inflammations	General system disorders NEC	Genrl	1968-2006	117	4286	22385	2979367	1.72	1.474	1.997	1.77	37.914	1.774	7.395e-10	1.78405743	0.54232429
Infliximab	Inflammatory bowel disease	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	10	539	22492	2983114	1.14	0.669	1.841	1.241	0.455	1.241	0.5	1.09516776	0.13102826
Infliximab	Inflammatory carcinoma of the breast	Breast and nipple neoplasms malignant	Breast neoplasms malignant and unspecified (incl nipple)	Neopl	1968-2006	2	20	22500	2983633	1.609	0.521	4.045	4.79	5.403	4.79	0.02	1.3541825	0.47561287
Infliximab	Influenza	Influenza viral infections	Viral infectious disorders	Infec	1968-2006	50	2864	22452	2980789	1.087	0.858	1.363	1.106	0.494	1.106	0.482	1.14846738	0.08342161
Infliximab	Influenza like illness	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	134	15558	22368	2968095	1.027	0.89	1.181	1.033	0.14	1.033	0.709	0.1701846	0.02664193
Infliximab	Infrequent bowel movements	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	1	133	22501	2983520	0.494	0.114	1.541	0.505	0.481	0.505	0.488	-0.0130888	-0.7052198
Infliximab	Infusion related reaction	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	852	1888	21650	2981765	16.555	15.642	17.508	27.162	12837.319	28.815	0	5.29771276	2.80668817
Infliximab	Infusion site bruising	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	30	22501	2983623	0.94	0.217	2.934	2.018	0.49	2.018	0.484	0.68809089	-0.0618754
Infliximab	Infusion site erythema	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	117	22501	2983536	0.458	0.106	1.43	0.445	0.67	0.445	0.413	0.0758668	-0.7808861
Infliximab	Infusion site haematoma	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	2	22501	2983651	1.265	0.292	3.974	15.628	8.47	15.628	0.004	0.95711984	0.23507212
Infliximab	Infusion site infection	Vascular infections	Infections - pathogen class unspecified	Infec	1968-2006	1	23	22501	2983630	1.02	0.236	3.186	2.757	1.024	2.757	0.312	0.75079293	0.01980263
Infliximab	Infusion site pain	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	3	170	22499	2983483	0.841	0.327	1.859	0.981	0.001	0.981	0.974	0.79061007	-0.1731636
Infliximab	Infusion site rash	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	19	22501	2983634	1.052	0.243	3.287	3.154	1.341	3.154	0.247	0.78788532	0.05069311
Infliximab	Infusion site reaction	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	5	204	22497	2983449	1.105	0.524	2.111	1.3	0.339	1.3	0.56	1.21538599	0.09984533
Infliximab	Infusion site swelling	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	3	50	22499	2983603	1.57	0.61	3.473	2.797	3.203	2.798	0.074	1.50709096	0.45107562
Infliximab	Ingrowing nail	Nail and nail bed conditions (excl infections and infestations)	Skin appendage conditions	Skin	1968-2006	5	142	22497	2983511	1.693	0.803	3.234	2.404	3.902	2.405	0.048	1.50343038	0.5265021
Infliximab	Inguinal hernia	Inguinal hernias	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	9	452	22493	2983201	1.449	0.827	2.395	1.681	2.368	1.682	0.124	1.15682873	0.37087366
Infliximab	Inguinal hernia, obstructive	Inguinal hernias	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	1	13	22501	2983640	1.161	0.268	3.634	5.388	3.202	5.389	0.074	0.84537553	0.1492817
Infliximab	Inguinal mass	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	3	21	22499	2983632	2.321	0.897	5.185	7.68	16.546	7.682	0.0000475	1.75079308	0.84199813
Infliximab	Initial insomnia	Disturbances in initiating and maintaining sleep	Sleep disorders and disturbances	Psych	1968-2006	1	987	22501	2982666	0.103	0.024	0.321	0.073	11.928	0.073	0.001	-2.0809296	-2.2730263
Infliximab	Injection site abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	1693	22501	2981960	0.167	0.038	0.521	0.122	6.251	0.121	0.012	-2.7856656	-1.7897615
Infliximab	Injection site dermatitis	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	190	22501	2983463	0.572	0.132	1.786	0.64	0.193	0.64	0.66	-0.2917057	-0.5586163
Infliximab	Injection site discomfort	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	124	22501	2983529	0.457	0.106	1.427	0.443	0.676	0.443	0.411	0.03627232	-0.7830719
Infliximab	Injection site erythema	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	10	4899	22492	2978754	0.114	0.067	0.185	0.108	74.338	0.108	6.584e-18	-1.7920058	-2.1715568
Infliximab	Injection site extravasation	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	3	555	22499	2983098	0.342	0.133	0.757	0.326	4.213	0.326	0.04	-0.3831685	-1.0729445
Infliximab	Injection site haemorrhage	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	7	8559	22495	2975094	0.076	0.04	0.133	0.07	86.985	0.07	1.093e-20	-3.0399929	-2.5770219
Infliximab	Injection site induration	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	559	22501	2983094	0.157	0.036	0.49	0.114	6.805	0.114	0.009	-1.3873363	-1.8515095
Infliximab	Injection site infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	3	462	22499	2983191	0.597	0.232	1.32	0.626	0.663	0.626	0.415	-0.1747764	-0.5158382
Infliximab	Injection site inflammation	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	5	4360	22497	2979293	0.632	0.3	1.207	0.656	0.907	0.656	0.341	-2.501522	-0.4588659
Infliximab	Injection site irritation	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	2	3201	22500	2980452	0.036	0.012	0.091	0.029	65.941	0.029	4.645e-16	-3.0698629	-3.3242363
Infliximab	Injection site necrosis	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	2218	22501	2981435	0.152	0.035	0.476	0.112	7.105	0.112	0.008	-3.1502261	-1.8838748
Infliximab	Injection site oedema	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	9	4576	22493	2979077	1.03	0.588	1.702	1.111	0.099	1.111	0.753	-1.8335439	0.0295588
Infliximab	Injection site pain	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	8	18578	22494	2965075	0.066	0.036	0.112	0.061	116.426	0.061	3.834e-27	-3.9804636	-2.7181005
Infliximab	Injection site paraesthesia	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	49	22501	2983604	0.849	0.196	2.649	1.483	0.154	1.483	0.695	0.53047566	-0.1636961
Infliximab	Injection site pruritus	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	3	1505	22499	2982148	0.127	0.049	0.281	0.112	21.294	0.112	3.939e-6	-1.6307265	-2.0635682
Infliximab	Injection site reaction	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	11	23893	22491	2959760	0.103	0.062	0.163	0.098	92.637	0.097	6.281e-22	-3.9287579	-2.2730263
Infliximab	Injection site swelling	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	2	1004	22500	2982649	0.115	0.037	0.289	0.094	17.295	0.094	0.00003201	-1.5189447	-2.1628232
Infliximab	Injection site thrombosis	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	2	100	22500	2983553	1.118	0.362	2.804	1.784	0.67	1.784	0.413	0.75563148	0.11154137
Infliximab	Injection site urticaria	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	3	791	22499	2982862	0.243	0.094	0.537	0.222	8.175	0.222	0.004	-0.8068501	-1.4146938
Infliximab	Injection site warmth	Injection and infusion site reactions	Administration site reactions	Genrl	1968-2006	1	339	22501	2983314	0.186	0.043	0.582	0.138	5.297	0.138	0.021	-0.8367905	-1.6820086
Infliximab	Injury	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	23	12774	22479	2970879	0.128	0.09	0.177	0.124	145.607	0.123	1.582e-33	-2.0288444	-2.055725
Infliximab	Injury asphyxiation	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	2	651	22500	2983002	0.233	0.075	0.584	0.205	6.193	0.205	0.013	-0.9839459	-1.4567168
Infliximab	Insomnia	Disturbances in initiating and maintaining sleep	Sleep disorders and disturbances	Psych	1968-2006	74	45514	22428	2938139	0.195	0.161	0.235	0.191	257.35	0.188	0	-2.2230625	-1.6347557
Infliximab	Inspiratory capacity decreased	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	13	22501	2983640	1.218	0.281	3.817	9.019	5.275	9.019	0.022	0.84537553	0.19721017
Infliximab	Insulin resistance	Hyperglycaemic conditions NEC	Glucose metabolism disorders (incl diabetes mellitus)	Metab	1968-2006	2	212	22500	2983441	0.545	0.177	1.367	0.565	0.651	0.565	0.42	0.19447947	-0.6069695
Infliximab	Intention tremor	Tremor (excl congenital)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	83	22501	2983570	0.686	0.159	2.14	0.903	0.01	0.903	0.921	0.28534087	-0.3768777
Infliximab	Intentional overdose	Overdoses	Medication errors	Inj&P	1968-2006	5	15934	22497	2967719	0.053	0.025	0.102	0.048	96.615	0.048	8.42e-23	-4.3441939	-2.9374634
Infliximab	Intentional self-injury	Suicidal and self-injurious behaviour	Suicidal and self-injurious behaviours NEC	Psych	1968-2006	1	1053	22501	2982600	0.078	0.018	0.245	0.054	16.641	0.054	0.00004517	-2.1634526	-2.5510465
Infliximab	Intercepted drug dispensing error	Medication errors NEC	Medication errors	Inj&P	1968-2006	1	79	22501	2983574	0.653	0.151	2.038	0.822	0.039	0.821	0.844	0.31211031	-0.4261781
Infliximab	Intercostal retraction	Respiratory signs and symptoms NEC	Respiratory disorders NEC	Resp	1968-2006	2	82	22500	2983571	1.042	0.338	2.613	1.555	0.389	1.555	0.533	0.87030356	0.04114194
Infliximab	Intermittent claudication	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	405	22500	2983248	0.373	0.121	0.936	0.352	2.365	0.352	0.124	-0.4427543	-0.9861769
Infliximab	Internal hernia	Abdominal hernias, site unspecified	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	1	6	22501	2983647	1.24	0.286	3.891	11.544	6.498	11.544	0.011	0.91547736	0.21511138
Infliximab	International normalised ratio abnormal	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	538	22501	2983115	0.127	0.029	0.399	0.092	9.073	0.092	0.003	-1.3429708	-2.0635682
Infliximab	International normalised ratio decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	9	1560	22493	2982093	0.369	0.211	0.611	0.359	10.135	0.358	0.001	-0.3614623	-0.9969586
Infliximab	International normalised ratio fluctuation	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	207	22501	2983446	0.342	0.079	1.069	0.3	1.657	0.3	0.198	-0.36536	-1.0729445
Infliximab	International normalised ratio increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	25	8841	22477	2974812	0.213	0.152	0.291	0.207	76.272	0.205	2.472e-18	-1.3886019	-1.5464631
Infliximab	Interstitial lung disease	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	168	4510	22334	2979143	2.605	2.292	2.952	2.759	176.691	2.775	2.558e-40	2.21727942	0.95743268
Infliximab	Intervertebral disc degeneration	Intervertebral disc disorders NEC	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	13	672	22489	2982981	1.235	0.774	1.89	1.335	1.052	1.335	0.305	1.18090672	0.21107097
Infliximab	Intervertebral disc disorder	Intervertebral disc disorders NEC	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	13	620	22489	2983033	1.255	0.786	1.921	1.36	1.192	1.361	0.275	1.27561704	0.22713557
Infliximab	Intervertebral disc displacement	Intervertebral disc disorders NEC	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	5	92	22497	2983561	2.466	1.168	4.724	4.832	13.561	4.833	0.000231	1.78658217	0.9025974
Infliximab	Intervertebral disc operation	Spine and spinal cord therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	2	81	22500	2983572	0.984	0.319	2.466	1.402	0.221	1.402	0.638	0.8769495	-0.0161294
Infliximab	Intervertebral disc protrusion	Intervertebral disc disorders NEC	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	31	1554	22471	2982099	1.164	0.861	1.546	1.201	1.013	1.202	0.314	1.30311735	0.15186235
Infliximab	Intervertebral discitis	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	12	78	22490	2983575	4.938	2.99	7.995	9.604	76.189	9.618	2.578e-18	2.94653737	1.59696039
Infliximab	Intestinal adenocarcinoma	Gastrointestinal neoplasms malignant NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	5	4	22497	2983649	15.822	2.969	51.396	76.255	180.341	76.377	4.083e-41	2.48006096	2.76140138
Infliximab	Intestinal anastomosis	Gastrointestinal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	3	8	22499	2983645	2.737	1.035	6.399	16.562	36.176	16.566	1.802e-9	1.8750032	1.00686243
Infliximab	Intestinal dilatation	Gastrointestinal atonic and hypomotility disorders NEC	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	4	197	22498	2983456	1.068	0.466	2.169	1.298	0.263	1.298	0.608	0.98644333	0.06578774
Infliximab	Intestinal fistula	Gastrointestinal fistulae	Gastrointestinal conditions NEC	Gastr	1968-2006	22	88	22480	2983565	10.012	6.075	15.821	16.501	234.436	16.514	0	3.64605593	2.30378437
Infliximab	Intestinal functional disorder	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	6	406	22496	2983247	0.943	0.476	1.716	1.038	0.008	1.038	0.928	0.76635493	-0.058689
Infliximab	Intestinal gangrene	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	86	22500	2983567	1.194	0.387	2.995	2.094	1.049	2.094	0.306	0.84402174	0.17730901
Infliximab	Intestinal haemorrhage	Intestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	4	403	22498	2983250	0.609	0.266	1.238	0.631	0.845	0.631	0.358	0.29421204	-0.495937
Infliximab	Intestinal infarction	Gastrointestinal vascular occlusion and infarction	Gastrointestinal vascular conditions	Gastr	1968-2006	7	311	22495	2983342	1.296	0.687	2.271	1.513	1.181	1.513	0.277	1.23184647	0.2592826
Infliximab	Intestinal ischaemia	Gastrointestinal vascular occlusion and infarction	Gastrointestinal vascular conditions	Gastr	1968-2006	18	759	22484	2982894	1.361	0.915	1.964	1.46	2.506	1.461	0.113	1.46777733	0.30821972
Infliximab	Intestinal malrotation	Intestinal disorders congenital	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	5	22501	2983648	1.182	0.273	3.702	5.899	3.875	5.899	0.049	0.92577585	0.16720792
Infliximab	Intestinal obstruction	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	95	3489	22407	2980164	2.438	2.054	2.876	2.585	87.394	2.591	8.89e-21	1.77400303	0.89117803
Infliximab	Intestinal operation	Gastrointestinal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	19	32	22483	2983621	12.644	7.031	19.776	28.3	251.305	28.336	0	3.84456902	2.53718279
Infliximab	Intestinal perforation	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	40	1292	22462	2982361	2.343	1.797	3.012	2.568	35.968	2.571	2.006e-9	1.8905386	0.85143216
Infliximab	Intestinal polyp	Benign neoplasms gastrointestinal (excl oral cavity)	Benign neoplasms gastrointestinal	Gastr	1968-2006	3	124	22499	2983529	1.015	0.394	2.244	1.289	0.189	1.289	0.664	1.02515681	0.01488861
Infliximab	Intestinal prolapse	Large intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	1	12	22501	2983641	1.069	0.247	3.342	3.503	1.559	3.504	0.212	0.85518395	0.06672363
Infliximab	Intestinal resection	Gastrointestinal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	11	42	22491	2983611	6.726	3.597	14.443	16.409	114.35	16.42	1.092e-26	3.09205458	1.90598061
Infliximab	Intestinal stenosis	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	28	148	22474	2983505	15.035	10.389	20.667	26.034	400.492	26.055	0	3.63454854	2.71038082
Infliximab	Intestinal stoma	Gastrointestinal therapeutic procedures NEC	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	4	22501	2983649	1.262	0.291	3.962	14.802	8.106	14.802	0.004	0.93614837	0.23269776
Infliximab	Intestinal strangulation	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	2	7	22500	2983646	2.024	0.648	5.187	21.379	22.835	21.379	1.765e-6	1.48006086	0.70507575
Infliximab	Intestinal ulcer	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	9	466	22493	2983187	2.373	1.354	3.924	3.25	13.149	3.251	0.0002876	1.12324684	0.86415498
Infliximab	Intra-abdominal haemorrhage	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	2	355	22500	2983298	0.365	0.118	0.916	0.341	2.506	0.341	0.113	-0.3027145	-1.0078579
Infliximab	Intra-cerebral aneurysm operation	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	1	4	22501	2983649	1.293	0.298	4.069	20.542	11.686	20.542	0.001	0.93614837	0.2569651
Infliximab	Intra-uterine death	Stillbirth and foetal death	Abortions and stillbirth	Preg	1968-2006	12	1259	22490	2982394	0.593	0.365	0.922	0.596	3.257	0.596	0.071	0.29477575	-0.5225609
Infliximab	Intracardiac thrombus	Cardiac disorders NEC	Cardiac disorder signs and symptoms	Card	1968-2006	8	445	22494	2983208	0.935	0.516	1.587	1.003	0	1.003	0.994	1.02437167	-0.0672087
Infliximab	Intracranial aneurysm	Central nervous system aneurysms	Central nervous system vascular disorders	Nerv	1968-2006	8	677	22494	2982976	0.824	0.455	1.399	0.867	0.161	0.867	0.688	0.54347477	-0.1935847
Infliximab	Intracranial hypotension	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	5	116	22497	2983537	1.718	0.815	3.283	2.473	4.127	2.473	0.042	1.64372795	0.54116082
Infliximab	Intracranial pressure increased	Increased intracranial pressure disorders	Increased intracranial pressure and hydrocephalus	Nerv	1968-2006	4	1863	22498	2981790	0.345	0.151	0.702	0.332	5.383	0.332	0.02	-1.5943025	-1.0642109
Infliximab	Intracranial tumour haemorrhage	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	1	23	22501	2983630	1.009	0.233	3.15	2.634	0.931	2.634	0.335	0.75079293	0.00895974
Infliximab	Intracranial venous sinus thrombosis	Cerebrovascular venous and sinus thrombosis	Central nervous system vascular disorders	Nerv	1968-2006	8	93	22494	2983560	3.347	1.842	5.715	6.026	30.416	6.029	3.486e-8	2.34673238	1.20806442
Infliximab	Intraocular melanoma	Ocular melanomas	Ocular neoplasms	Neopl	1968-2006	3	22	22499	2983631	2.239	0.867	4.989	7.37	14.192	7.37	0.0001651	1.74166709	0.80602934
Infliximab	Intraocular pressure decreased	Ophthalmic function diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	50	22501	2983603	0.908	0.21	2.834	1.813	0.344	1.813	0.558	0.52263848	-0.0965109
Infliximab	Intraocular pressure increased	Ophthalmic function diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	5	1100	22497	2982553	0.337	0.16	0.643	0.323	7.036	0.322	0.008	-0.6391746	-1.0876723
Infliximab	Intraspinal abscess	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	28	22500	2983625	1.541	0.499	3.87	4.001	4.265	4.001	0.039	1.28184581	0.43243156
Infliximab	Intraventricular haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	2	304	22500	2983349	0.405	0.131	1.016	0.389	1.91	0.389	0.167	-0.1443324	-0.9038682
Infliximab	Intubation complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	49	22500	2983604	1.326	0.43	3.326	2.641	1.922	2.641	0.166	1.10760111	0.28216689
Infliximab	Intussusception	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	3	54	22499	2983599	1.848	0.717	4.092	4.11	6.294	4.111	0.012	1.47648913	0.61410397
Infliximab	Investigation	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	1	5	22501	2983648	1.266	0.292	3.978	11.217	8.491	11.221	0.004	0.92577585	0.23586232
Infliximab	Investigation abnormal	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	1	32	22501	2983621	0.962	0.222	3.003	2.221	0.609	2.221	0.435	0.67066536	-0.0387408
Infliximab	Iridectomy	Iris and ciliary body therapeutic procedures	Eye therapeutic procedures	Surg	1968-2006	1	4	22501	2983649	1.277	0.294	4.016	18.603	9.738	18.603	0.002	0.93614837	0.24451358
Infliximab	Iridocyclitis	Iris and uveal tract infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	120	22501	2983533	0.512	0.118	1.597	0.537	0.402	0.537	0.526	0.05876453	-0.6694307
Infliximab	Iris adhesions	Iris and ciliary body structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	51	22501	2983602	0.817	0.189	2.549	1.338	0.085	1.338	0.77	0.51484364	-0.2021162
Infliximab	Iris disorder	Iris and ciliary body structural change, deposit and degeneration	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	279	22501	2983374	0.288	0.067	0.9	0.235	2.443	0.235	0.118	-0.6413265	-1.2447948
Infliximab	Iritis	Iris and uveal tract infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	8	645	22494	2983008	1.488	0.821	2.526	1.757	2.567	1.757	0.109	0.60101905	0.39743294
Infliximab	Iron binding capacity total	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	2	1	22500	2983652	2.201	0.689	5.863	82.903	44.403	83.013	2.672e-11	1.54208236	0.7889118
Infliximab	Iron deficiency	Iron deficiencies	Iron and trace metal metabolism disorders	Metab	1968-2006	10	228	22492	2983425	2.028	1.191	3.276	2.565	8.865	2.566	0.003	1.97261579	0.70705009
Infliximab	Iron deficiency anaemia	Anaemia deficiencies	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	25	5720	22477	2977933	1.591	1.136	2.178	1.699	6.973	1.699	0.008	-0.7727006	0.46436275
Infliximab	Iron metabolism disorder	Iron metabolism disorders NEC	Iron and trace metal metabolism disorders	Metab	1968-2006	1	23	22501	2983630	1.109	0.256	3.467	4.26	2.109	4.26	0.146	0.75079293	0.10345871
Infliximab	Irritability	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	8	6271	22494	2977382	0.084	0.047	0.143	0.079	86.72	0.078	1.25e-20	-2.428919	-2.4769385
Infliximab	Irritable bowel syndrome	Gastrointestinal spastic and hypermotility disorders	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	17	1227	22485	2982426	0.844	0.561	1.229	0.863	0.36	0.863	0.548	0.79227866	-0.1696028
Infliximab	Ischaemia	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	14	688	22488	2982965	1.047	0.667	1.58	1.102	0.128	1.102	0.721	1.2507806	0.04592893
Infliximab	Ischaemic cardiomyopathy	Cardiomyopathies	Myocardial disorders	Card	1968-2006	11	464	22491	2983189	1.581	0.952	2.503	1.824	3.874	1.825	0.049	1.38628201	0.45805756
Infliximab	Ischaemic cerebral infarction	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	2	113	22500	2983540	0.98	0.318	2.456	1.39	0.21	1.391	0.647	0.67813693	-0.0202027
Infliximab	Ischaemic hepatitis	Hepatocellular damage and hepatitis NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	2	146	22500	2983507	0.697	0.226	1.746	0.802	0.099	0.802	0.753	0.49829672	-0.3609699
Infliximab	Ischaemic neuropathy	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	1	11	22501	2983642	1.138	0.263	3.559	5.01	2.665	5.011	0.103	0.86505951	0.12927234
Infliximab	Ischaemic stroke	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	10	1384	22492	2982269	0.458	0.269	0.739	0.452	6.572	0.452	0.01	-0.0674006	-0.7808861
Infliximab	Ischaemic ulcer	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	16	22501	2983637	1.103	0.255	3.45	3.99	2.021	3.99	0.155	0.81634411	0.09803374
Infliximab	Jaundice	Cholestasis and jaundice	Hepatic and hepatobiliary disorders	Hepat	1968-2006	48	14882	22454	2968771	0.472	0.371	0.594	0.468	29.052	0.467	7.047e-8	-1.2203987	-0.7507763
Infliximab	Jaundice cholestatic	Cholestasis and jaundice	Hepatic and hepatobiliary disorders	Hepat	1968-2006	4	5004	22498	2978649	0.328	0.143	0.667	0.316	5.997	0.316	0.014	-2.9576097	-1.1147417
Infliximab	Jaundice neonatal	Neonatal hepatobiliary disorders	Neonatal and perinatal conditions	Preg	1968-2006	3	471	22499	2983182	0.52	0.202	1.149	0.528	1.26	0.528	0.262	-0.1963106	-0.6539265
Infliximab	Jaw disorder	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	6	696	22496	2982957	0.551	0.278	1.002	0.554	2.11	0.554	0.146	0.15124167	-0.5960205
Infliximab	Jaw fracture	Skull fractures, facial bone fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	1	122	22501	2983531	0.507	0.117	1.582	0.529	0.422	0.529	0.516	0.0474746	-0.6792443
Infliximab	Joint abscess	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	1	16	22501	2983637	1.137	0.263	3.555	4.471	2.622	4.472	0.105	0.81634411	0.12839321
Infliximab	Joint arthroplasty	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	16	91	22486	2983562	5.181	3.364	7.825	9.091	92.919	9.101	5.449e-22	3.22783474	1.64499809
Infliximab	Joint contracture	Joint related disorders NEC	Joint disorders	Musc	1968-2006	1	146	22501	2983507	0.446	0.103	1.392	0.435	0.744	0.435	0.388	-0.0815331	-0.8074363
Infliximab	Joint crepitation	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	1	86	22501	2983567	0.545	0.126	1.7	0.59	0.279	0.59	0.597	0.26558476	-0.6069695
Infliximab	Joint destruction	Joint related disorders NEC	Joint disorders	Musc	1968-2006	1	36	22501	2983617	0.851	0.197	2.657	1.488	0.162	1.488	0.687	0.63643321	-0.1613432
Infliximab	Joint dislocation	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	21	660	22481	2982993	1.776	1.23	2.498	1.96	9.332	1.961	0.002	1.84005548	0.57436364
Infliximab	Joint dislocation postoperative	Musculoskeletal procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	5	22501	2983648	1.237	0.285	3.879	10.01	6.302	10.01	0.012	0.92577585	0.21268909
Infliximab	Joint effusion	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	32	579	22470	2983074	3.187	2.368	4.216	3.773	59.127	3.777	1.478e-14	2.55468305	1.15908004
Infliximab	Joint injury	Limb injuries NEC (incl traumatic amputation)	Bone and joint injuries	Inj&P	1968-2006	3	727	22499	2982926	0.306	0.119	0.677	0.287	5.303	0.287	0.021	-0.703679	-1.1841702
Infliximab	Joint irrigation	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	0	22501	2983653	1.344	0.308	4.254	1075.473	51.196	1083.041	8.358e-13	0.97840063	0.29565024
Infliximab	Joint lock	Joint related disorders NEC	Joint disorders	Musc	1968-2006	8	89	22494	2983564	2.7	1.49	4.591	4.331	17.837	4.332	0.00002407	2.37154529	0.99325177
Infliximab	Joint range of motion decreased	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	10	327	22492	2983326	1.39	0.816	2.244	1.576	2.01	1.576	0.156	1.63181353	0.32930375
Infliximab	Joint sprain	Limb injuries NEC (incl traumatic amputation)	Bone and joint injuries	Inj&P	1968-2006	6	567	22496	2983086	0.689	0.348	1.254	0.715	0.664	0.715	0.415	0.39322423	-0.372514
Infliximab	Joint stiffness	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	65	1991	22437	2981662	2.171	1.764	2.648	2.313	45.6	2.317	1.45e-11	1.99786489	0.77518789
Infliximab	Joint surgery	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	4	30	22498	2983623	2.426	1.057	4.952	6.179	14.34	6.181	0.0001526	1.98395928	0.88624381
Infliximab	Joint swelling	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	169	4192	22333	2979461	2.179	1.917	2.468	2.269	114.501	2.279	1.012e-26	2.32426883	0.77886606
Infliximab	Joint tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	7	4	22495	2983649	17.274	4.436	39.701	63.602	182.703	63.642	1.245e-41	2.87500336	2.84920248
Infliximab	Joint warmth	Joint related signs and symptoms	Joint disorders	Musc	1968-2006	1	26	22501	2983627	0.898	0.208	2.804	1.768	0.309	1.768	0.578	0.72358631	-0.1075852
Infliximab	Jugular vein distension	Site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	75	22501	2983578	0.65	0.15	2.028	0.813	0.042	0.813	0.837	0.33938578	-0.4307829
Infliximab	Jugular vein thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	5	200	22497	2983453	1.14	0.541	2.178	1.359	0.456	1.359	0.5	1.23233133	0.13102826
Infliximab	Juvenile arthritis	Rheumatoid arthropathies	Joint disorders	Musc	1968-2006	8	118	22494	2983535	2.548	1.406	4.33	3.84	15.292	3.842	0.0000921	2.20063028	0.93530874
Infliximab	Kaposis sarcoma	Kaposis sarcomas	Soft tissue sarcomas	Neopl	1968-2006	7	288	22495	2983365	1.452	0.77	2.545	1.76	2.181	1.76	0.14	1.307272	0.37294192
Infliximab	Kawasakis disease	Inflammatory disorders following infection	Ancillary infectious topics	Infec	1968-2006	1	63	22501	2983590	0.777	0.18	2.427	1.19	0.03	1.19	0.863	0.42444935	-0.2523149
Infliximab	Keloid scar	Skin dystrophies	Cornification and dystrophic skin disorders	Skin	1968-2006	1	55	22501	2983598	0.808	0.187	2.522	1.31	0.07	1.31	0.791	0.48407867	-0.2131932
Infliximab	Keratitis	Corneal infections, oedemas and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	9	2337	22493	2981316	1.405	0.802	2.322	1.609	2.031	1.609	0.154	-0.9042073	0.3400373
Infliximab	Keratitis herpetic	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	7	79	22495	2983574	3.189	1.686	5.622	6.335	26.967	6.337	2.07e-7	2.27214127	1.15970739
Infliximab	Keratitis sclerosing	Corneal infections, oedemas and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	0	22501	2983653	1.345	0.308	4.256	1075.772	51.692	1083.348	6.493e-13	0.97840063	0.29639401
Infliximab	Keratoacanthoma	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	3	20	22499	2983633	2.433	0.938	5.465	11.132	20.594	11.133	5.678e-6	1.75997716	0.88912506
Infliximab	Keratoconjunctivitis sicca	Lacrimal disorders	Eye disorders NEC	Eye	1968-2006	4	335	22498	2983318	0.508	0.222	1.032	0.51	1.866	0.51	0.172	0.48818858	-0.6772738
Infliximab	Keratoderma blenorrhagica	Hyperkeratoses	Cornification and dystrophic skin disorders	Skin	1968-2006	2	1	22500	2983652	2.356	0.712	6.852	219.461	71.724	221.312	2.475e-17	1.54208236	0.85696527
Infliximab	Keratorhexis	Eye injuries NEC	Injuries NEC	Inj&P	1968-2006	1	2	22501	2983651	1.361	0.311	4.317	51.572	35.253	51.572	2.895e-9	0.95711984	0.30821972
Infliximab	Ketoacidosis	Metabolic acidoses (excl diabetic acidoses)	Acid-base disorders	Metab	1968-2006	1	1283	22501	2982370	0.173	0.04	0.54	0.128	5.9	0.127	0.015	-2.4189663	-1.7544637
Infliximab	Kidney enlargement	Renal structural abnormalities and trauma	Renal disorders (excl nephropathies)	Renal	1968-2006	1	143	22501	2983510	0.399	0.092	1.247	0.37	1.082	0.37	0.298	-0.066024	-0.9187939
Infliximab	Kidney infection	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	19	892	22483	2982761	1.156	0.785	1.652	1.212	0.683	1.212	0.408	1.34365147	0.14496577
Infliximab	Kidney rupture	Renal and urinary tract injuries NEC	Injuries NEC	Inj&P	1968-2006	3	20	22499	2983633	2.49	0.958	5.618	11.897	22.999	11.897	1.621e-6	1.75997716	0.91228271
Infliximab	Klebsiella bacteraemia	Klebsiella infections	Bacterial infectious disorders	Infec	1968-2006	3	37	22499	2983616	1.895	0.736	4.199	4.39	6.993	4.391	0.008	1.61128199	0.63921884
Infliximab	Klebsiella infection	Klebsiella infections	Bacterial infectious disorders	Infec	1968-2006	20	644	22482	2983009	1.717	1.179	2.434	1.881	7.965	1.881	0.005	1.80337565	0.54057858
Infliximab	Klebsiella sepsis	Klebsiella infections	Bacterial infectious disorders	Infec	1968-2006	5	75	22497	2983578	2.426	1.149	4.646	4.487	12.906	4.488	0.0003276	1.89707354	0.88624381
Infliximab	Knee arthroplasty	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	45	794	22457	2982859	2.673	2.082	3.39	2.972	54.741	2.976	1.375e-13	2.64836353	0.98320144
Infliximab	Knee operation	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	17	226	22485	2983427	2.883	1.916	4.202	3.668	30.001	3.671	4.317e-8	2.66382622	1.05883142
Infliximab	Kyphosis	Spine and neck deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	3	130	22499	2983523	1.154	0.448	2.551	1.582	0.609	1.582	0.435	0.99231363	0.14323417
Infliximab	Labile blood pressure	Blood pressure disorders NEC	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	1	406	22501	2983247	0.305	0.07	0.952	0.253	2.164	0.253	0.141	-1.0277172	-1.1874435
Infliximab	Laboratory test abnormal	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	53	7865	22449	2975788	0.957	0.76	1.192	0.966	0.06	0.966	0.806	-0.1730957	-0.0439519
Infliximab	Laboratory test interference	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	2	1225	22500	2982428	0.418	0.135	1.048	0.403	1.746	0.403	0.186	-1.7747681	-0.8722738
Infliximab	Labour induction	Obstetric therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	30	22501	2983623	0.89	0.206	2.78	1.688	0.28	1.688	0.596	0.68809089	-0.1165338
Infliximab	Labyrinthitis	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	4	282	22498	2983371	0.931	0.406	1.891	1.076	0.021	1.076	0.886	0.65982095	-0.071496
Infliximab	Laceration	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	9	1186	22493	2982467	0.51	0.291	0.843	0.507	4.233	0.507	0.04	-0.0034476	-0.6733446
Infliximab	Lacrimal duct neoplasm	Ocular neoplasms malignancy unspecified	Ocular neoplasms	Neopl	1968-2006	1	0	22501	2983653	1.345	0.308	4.256	1075.772	51.692	1083.348	6.493e-13	0.97840063	0.29639401
Infliximab	Lacrimation decreased	Lacrimal disorders	Eye disorders NEC	Eye	1968-2006	1	56	22501	2983597	0.815	0.188	2.543	1.344	0.082	1.344	0.774	0.47648884	-0.2045672
Infliximab	Lacrimation increased	Lacrimal disorders	Eye disorders NEC	Eye	1968-2006	14	1574	22488	2982079	0.595	0.38	0.898	0.598	3.767	0.598	0.052	0.20748272	-0.5191939
Infliximab	Lactescent serum	Haematological analyses NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	1	0	22501	2983653	1.368	0.312	4.344	1085.895	76.698	1093.547	1.992e-18	0.97840063	0.31334982
Infliximab	Lactic acidosis	Metabolic acidoses (excl diabetic acidoses)	Acid-base disorders	Metab	1968-2006	8	4298	22494	2979355	0.198	0.109	0.336	0.187	28.055	0.186	1.179e-7	-1.8974831	-1.6194882
Infliximab	Lactobacillus infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	20	22501	2983633	0.989	0.229	3.089	2.438	0.787	2.438	0.375	0.77852244	-0.0110609
Infliximab	Lactose intolerance	Sugar intolerance (excl glucose intolerance)	Food intolerance syndromes	Metab	1968-2006	1	160	22501	2983493	0.462	0.107	1.442	0.453	0.647	0.453	0.421	-0.1517835	-0.7721904
Infliximab	Lacunar infarction	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	6	616	22496	2983037	0.626	0.316	1.14	0.641	1.179	0.641	0.277	0.29647098	-0.4684049
Infliximab	Laparoscopy	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	1	6	22501	2983647	1.208	0.279	3.786	6.954	4.828	6.954	0.028	0.91547736	0.1889661
Infliximab	Large cell carcinoma of the respiratory tract stage unspecified	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	30	22500	2983623	1.548	0.501	3.889	4.149	4.38	4.149	0.036	1.26431441	0.43696378
Infliximab	Large granular lymphocytosis	Leukaemias chronic T-cell	Leukaemias	Neopl	1968-2006	2	7	22500	2983646	1.877	0.605	4.753	11.088	13.386	11.088	0.0002535	1.48006086	0.62967476
Infliximab	Large intestinal haemorrhage	Intestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	2	301	22500	2983352	0.524	0.17	1.315	0.538	0.779	0.538	0.378	-0.1344516	-0.6462636
Infliximab	Large intestinal obstruction	Large intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	1	41	22501	2983612	0.842	0.195	2.628	1.456	0.138	1.456	0.71	0.59475445	-0.1719753
Infliximab	Large intestinal stricture	Large intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	1	11	22501	2983642	1.126	0.26	3.521	4.575	2.43	4.576	0.119	0.86505951	0.11867153
Infliximab	Large intestinal ulcer	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	8	408	22494	2983245	1.048	0.579	1.779	1.147	0.147	1.147	0.701	1.11838537	0.04688359
Infliximab	Large intestinal ulcer haemorrhage	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	49	22501	2983604	0.774	0.179	2.417	1.179	0.027	1.179	0.87	0.53047566	-0.2561834
Infliximab	Large intestine carcinoma	Gastrointestinal neoplasms malignant NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	5	28	22497	2983625	3.389	1.583	6.708	12.24	36.777	12.245	1.324e-9	2.25562825	1.22053489
Infliximab	Large intestine perforation	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	25	857	22477	2982796	2.028	1.449	2.777	2.238	16.391	2.239	0.00005154	1.7627981	0.70705009
Infliximab	Laryngeal cancer	Laryngeal neoplasms malignant	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	14	165	22488	2983488	4.864	3.073	7.504	8.322	77.901	8.329	1.083e-18	2.66954033	1.58186114
Infliximab	Laryngeal disorder	Laryngeal and adjacent sites disorders NEC (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	4	164	22498	2983489	1.269	0.554	2.579	1.669	1.024	1.669	0.312	1.13626249	0.23822919
Infliximab	Laryngeal dyspnoea	Laryngeal and adjacent sites disorders NEC (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	16	22501	2983637	1.062	0.246	3.32	3.313	1.46	3.313	0.227	0.81634411	0.06015392
Infliximab	Laryngeal erythema	Laryngeal and adjacent sites disorders NEC (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	9	22501	2983644	1.191	0.275	3.729	6.865	4.127	6.865	0.042	0.88501574	0.17479329
Infliximab	Laryngeal neoplasm	Laryngeal neoplasms malignancy unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	40	22501	2983613	1.136	0.263	3.553	4.844	2.619	4.844	0.106	0.60299444	0.12751332
Infliximab	Laryngeal obstruction	Laryngeal spasm, oedema and obstruction	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	11	22501	2983642	1.11	0.257	3.472	4.038	2.148	4.038	0.143	0.86505951	0.10436002
Infliximab	Laryngeal oedema	Laryngeal spasm, oedema and obstruction	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	35	3516	22467	2980137	1.931	1.454	2.524	2.063	18.611	2.065	0.00001603	0.37181704	0.658038
Infliximab	Laryngitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	13	1264	22489	2982389	1.2	0.752	1.836	1.292	0.826	1.292	0.363	0.39553887	0.18232156
Infliximab	Laryngitis viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	1	4	22501	2983649	1.274	0.293	4.003	12.309	9.227	12.309	0.002	0.93614837	0.24216156
Infliximab	Laryngospasm	Laryngeal spasm, oedema and obstruction	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	6	4647	22496	2979006	0.534	0.269	0.972	0.537	2.38	0.537	0.123	-2.3687938	-0.6273594
Infliximab	Laryngotracheitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	8	22501	2983645	1.219	0.281	3.82	7.462	5.296	7.462	0.021	0.89509832	0.19803085
Infliximab	Larynx irritation	Laryngeal and adjacent sites disorders NEC (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	12	22501	2983641	1.081	0.25	3.379	3.437	1.705	3.438	0.192	0.85518395	0.07788654
Infliximab	Left ventricular end-diastolic pressure decreased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	1	22501	2983652	1.353	0.31	4.288	87.514	29.871	87.514	4.617e-8	0.967721	0.30232435
Infliximab	Left ventricular end-diastolic pressure increased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	32	22500	2983621	1.687	0.546	4.246	5.773	6.897	5.773	0.009	1.24699348	0.5229518
Infliximab	Left ventricular failure	Left ventricular failures	Heart failures	Card	1968-2006	21	1758	22481	2981895	1.365	0.945	1.919	1.452	2.825	1.452	0.093	0.60814894	0.31115443
Infliximab	Leg amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	22	824	22480	2982829	1.518	1.061	2.12	1.629	5.141	1.63	0.023	1.63800431	0.41739368
Infliximab	Legionella infection	Legionella infections	Bacterial infectious disorders	Infec	1968-2006	25	41	22477	2983612	16.752	11.562	23.287	28.641	403.881	28.674	0	4.11036287	2.81851765
Infliximab	Legionella serology	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	2	1	22500	2983652	2.53	0.73	11.587	221.123	107.911	221.123	2.811e-25	1.54208236	0.9282193
Infliximab	Leiomyoma	Soft tissue neoplasms benign NEC	Soft tissue neoplasms benign	Neopl	1968-2006	3	91	22499	2983562	1.366	0.531	3.021	2.129	1.673	2.129	0.196	1.22051305	0.31188676
Infliximab	Leiomyosarcoma	Leiomyosarcomas	Soft tissue sarcomas	Neopl	1968-2006	1	50	22501	2983603	0.759	0.175	2.368	1.126	0.014	1.126	0.907	0.52263848	-0.2757535
Infliximab	Leiomyosarcoma metastatic	Leiomyosarcomas	Soft tissue sarcomas	Neopl	1968-2006	1	2	22501	2983651	1.345	0.308	4.259	38.748	25.625	38.748	4.146e-7	0.95711984	0.29639401
Infliximab	Leishmaniasis	Leishmania infections	Protozoal infectious disorders	Infec	1968-2006	3	20	22499	2983633	2.417	0.932	5.424	9.24	19.919	9.24	0.00000808	1.75997716	0.8825271
Infliximab	Lens dislocation	Lens structural change, deposit and degeneration (excl cataracts)	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	16	22501	2983637	1.128	0.261	3.529	4.751	2.466	4.751	0.116	0.81634411	0.12044615
Infliximab	Lentigo	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	2	22	22500	2983631	1.591	0.515	3.998	4.587	5.072	4.588	0.024	1.33575551	0.46436275
Infliximab	Lentigo maligna stage unspecified	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	3	14	22499	2983639	2.551	0.978	5.787	13.554	25.866	13.556	3.66e-7	1.81634422	0.93648544
Infliximab	Leprosy	Leprous infections	Mycobacterial infectious disorders	Infec	1968-2006	6	16	22496	2983637	5.645	2.362	19.106	22.788	89.394	22.806	3.235e-21	2.57657521	1.7307702
Infliximab	Leriche syndrome	Aortic necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	26	22500	2983627	1.725	0.558	4.345	6.804	7.88	6.804	0.005	1.29959284	0.54522705
Infliximab	Lesion of sciatic nerve	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	4	36	22498	2983617	2.714	1.178	5.582	7.928	21.376	7.931	3.775e-6	1.9332102	0.99842356
Infliximab	Lethargy	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	58	8706	22444	2974947	0.462	0.371	0.57	0.456	37.37	0.455	9.77e-10	-0.1898887	-0.7721904
Infliximab	Leukaemia	Leukaemias NEC	Leukaemias	Neopl	1968-2006	18	1154	22484	2982499	1.617	1.088	2.334	1.77	5.839	1.77	0.016	0.94776076	0.48057258
Infliximab	Leukaemia monocytic	Leukaemias myeloid NEC	Leukaemias	Neopl	1968-2006	1	13	22501	2983640	1.197	0.277	3.751	6.844	4.342	6.845	0.037	0.84537553	0.17981843
Infliximab	Leukaemia plasmacytic	Multiple myelomas	Plasma cell neoplasms	Neopl	1968-2006	1	58	22501	2983595	0.747	0.173	2.331	1.085	0.007	1.085	0.936	0.46142791	-0.2916901
Infliximab	Leukaemia recurrent	Leukaemias NEC	Leukaemias	Neopl	1968-2006	3	179	22499	2983474	0.694	0.27	1.535	0.758	0.229	0.758	0.632	0.74886559	-0.3652833
Infliximab	Leukaemic infiltration pulmonary	Leukaemias NEC	Leukaemias	Neopl	1968-2006	1	3	22501	2983650	1.296	0.298	4.079	19.732	12.106	19.732	0.001	0.946596	0.2592826
Infliximab	Leukaemoid reaction	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	4	101	22498	2983552	2.589	1.126	5.304	6.914	17.963	6.915	0.00002252	1.47434119	0.9512717
Infliximab	Leukocytoclastic vasculitis	Skin vasculitides	Skin vascular abnormalities	Skin	1968-2006	38	1067	22464	2982586	2.297	1.75	2.972	2.517	32.709	2.52	1.07e-8	2.06127936	0.83160392
Infliximab	Leukocytosis	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	91	10347	22411	2973306	1.765	1.481	2.089	1.826	32.74	1.83	1.054e-8	0.20152829	0.56815069
Infliximab	Leukocyturia	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	7	88	22495	2983565	2.596	1.376	4.556	4.292	15.618	4.294	0.00007752	2.2141884	0.9539718
Infliximab	Leukoencephalopathy	Encephalopathies NEC	Encephalopathies	Nerv	1968-2006	8	281	22494	2983372	1.369	0.756	2.325	1.58	1.691	1.58	0.193	1.49753953	0.31408055
Infliximab	Leukopenia	Leukopenias NEC	White blood cell disorders	Blood	1968-2006	152	30953	22350	2952700	1.153	1.008	1.315	1.163	3.423	1.165	0.064	-0.6378152	0.14236724
Infliximab	Leukoplakia	Skin preneoplastic conditions NEC	Cornification and dystrophic skin disorders	Skin	1968-2006	4	45	22498	2983608	2.394	1.043	4.886	5.705	13.631	5.706	0.0002224	1.86028413	0.87296561
Infliximab	Leukostasis	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	1	20	22501	2983633	0.969	0.224	3.026	2.229	0.657	2.229	0.418	0.77852244	-0.0314907
Infliximab	Lice infestation	Ectoparasitic infestations	Ectoparasitic disorders	Infec	1968-2006	1	44	22501	2983609	0.876	0.203	2.735	1.612	0.232	1.612	0.63	0.5703131	-0.1323892
Infliximab	Lichen planus	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	18	792	22484	2982861	2.771	1.863	3.998	3.451	28.459	3.453	9.572e-8	1.41640319	1.01920827
Infliximab	Lichenification	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	2	41	22500	2983612	1.37	0.444	3.438	2.866	2.306	2.866	0.129	1.17152386	0.31481074
Infliximab	Lichenoid keratosis	Hyperkeratoses	Cornification and dystrophic skin disorders	Skin	1968-2006	4	245	22498	2983408	1.267	0.553	2.575	1.669	1.01	1.669	0.315	0.79301819	0.2366519
Infliximab	Life support	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	2	168	22500	2983485	0.76	0.246	1.906	0.913	0.017	0.913	0.898	0.38975988	-0.2744368
Infliximab	Ligament disorder	Ligament disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	3	130	22499	2983523	1.163	0.452	2.571	1.592	0.643	1.592	0.423	0.99231363	0.15100287
Infliximab	Ligament injury	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	3	151	22499	2983502	0.934	0.363	2.064	1.138	0.049	1.138	0.825	0.88291474	-0.0682788
Infliximab	Ligament laxity	Joint related disorders NEC	Joint disorders	Musc	1968-2006	1	23	22501	2983630	0.952	0.22	2.973	2.12	0.556	2.12	0.456	0.75079293	-0.0491902
Infliximab	Ligament rupture	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	2	58	22500	2983595	1.167	0.378	2.926	1.989	0.902	1.989	0.342	1.03891865	0.15443635
Infliximab	Light chain analysis	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	2	22501	2983651	1.366	0.312	4.335	51.044	39.01	51.044	4.216e-10	0.95711984	0.31188676
Infliximab	Light chain analysis increased	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	1	23	22501	2983630	0.97	0.224	3.028	2.262	0.657	2.262	0.418	0.75079293	-0.0304592
Infliximab	Limb discomfort	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	4	380	22498	2983273	0.642	0.28	1.304	0.671	0.627	0.671	0.428	0.35694761	-0.443167
Infliximab	Limb injury	Limb injuries NEC (incl traumatic amputation)	Bone and joint injuries	Inj&P	1968-2006	18	1189	22484	2982464	0.873	0.587	1.26	0.894	0.218	0.894	0.641	0.90957783	-0.1358197
Infliximab	Limb operation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	5	60	22497	2983593	2.223	1.053	4.251	3.855	9.893	3.856	0.002	2.00212916	0.79885763
Infliximab	Lip and/or oral cavity cancer	Lip and oral cavity neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	7	134	22495	2983519	3.025	1.601	5.324	5.782	23.433	5.783	1.294e-6	1.94965518	1.10691109
Infliximab	Lip disorder	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	3	397	22499	2983256	0.697	0.271	1.541	0.762	0.219	0.762	0.64	-0.00891	-0.3609699
Infliximab	Lip neoplasm	Lip and oral cavity neoplasms malignancy unspecified	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	2	22501	2983651	1.273	0.293	4.003	14.731	9.292	14.731	0.002	0.95711984	0.24137632
Infliximab	Lip neoplasm malignant stage unspecified	Lip and oral cavity neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	4	13	22498	2983640	3.568	1.463	9.149	21.151	54.589	21.157	1.485e-13	2.13827238	1.27200521
Infliximab	Lip pain	Oral soft tissue pain and paraesthesia	Oral soft tissue conditions	Gastr	1968-2006	2	173	22500	2983480	0.585	0.19	1.467	0.627	0.445	0.627	0.505	0.36619082	-0.5361434
Infliximab	Lip ulceration	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	4	208	22498	2983445	1.223	0.534	2.484	1.574	0.809	1.574	0.369	0.93977161	0.20130686
Infliximab	Lipase	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	1	8	22501	2983645	1.132	0.262	3.541	4.607	2.559	4.608	0.11	0.89509832	0.12398598
Infliximab	Lipase increased	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	16	2193	22486	2981460	0.763	0.501	1.124	0.777	1.011	0.776	0.315	-0.0566062	-0.2704972
Infliximab	Lipidosis	Lysosomal storage disorders	Metabolic and nutritional disorders congenital	Cong	1968-2006	1	10	22501	2983643	1.3	0.299	4.094	16.127	12.659	16.127	0.0003738	0.87500312	0.26236426
Infliximab	Lipids increased	Lipoprotein and lipid tests NEC	Lipid analyses	Inv	1968-2006	1	257	22501	2983396	0.314	0.072	0.98	0.262	2.027	0.262	0.154	-0.5624595	-1.1583623
Infliximab	Lipodystrophy acquired	Lipodystrophies	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	1	710	22501	2982943	0.177	0.041	0.552	0.133	5.705	0.133	0.017	-1.6715755	-1.7316055
Infliximab	Lipogranuloma	Inflammations	General system disorders NEC	Genrl	1968-2006	1	6	22501	2983647	1.218	0.281	3.818	8.28	5.247	8.28	0.022	0.91547736	0.19721017
Infliximab	Lipohypertrophy	Lipodystrophies	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	1	36	22501	2983617	0.89	0.206	2.779	1.719	0.278	1.719	0.598	0.63643321	-0.1165338
Infliximab	Lipoma	Soft tissue neoplasms benign NEC	Soft tissue neoplasms benign	Neopl	1968-2006	10	266	22492	2983387	2.054	1.206	3.318	2.599	9.196	2.6	0.002	1.83213062	0.71978911
Infliximab	Lipomatosis	Lipid metabolism and deposit disorders NEC	Lipid metabolism disorders	Metab	1968-2006	1	60	22501	2983593	0.644	0.149	2.01	0.797	0.05	0.797	0.823	0.44652257	-0.4400566
Infliximab	Listeria encephalitis	Listeria infections	Bacterial infectious disorders	Infec	1968-2006	8	4	22494	2983649	32.682	16.743	58.251	155.63	323.382	155.972	0	3.03498481	3.48682447
Infliximab	Listeria sepsis	Listeria infections	Bacterial infectious disorders	Infec	1968-2006	8	11	22494	2983642	10.146	3.639	26.178	31.569	138.761	31.608	4.967e-32	2.96723479	2.31707954
Infliximab	Listeriosis	Listeria infections	Bacterial infectious disorders	Infec	1968-2006	72	78	22430	2983575	24.355	19.974	29.463	56.863	1691.945	57.108	0	5.09296547	3.19273717
Infliximab	Listless	Mood disorders NEC	Mood disorders and disturbances NEC	Psych	1968-2006	10	355	22492	2983298	1.651	0.969	2.666	1.94	4.391	1.94	0.036	1.54841767	0.50138116
Infliximab	Lithotripsy	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	8	22501	2983645	1.221	0.282	3.828	7.679	5.388	7.679	0.02	0.89509832	0.1996702
Infliximab	Livedo reticularis	Skin vasomotor conditions	Skin vascular abnormalities	Skin	1968-2006	12	411	22490	2983242	1.699	1.045	2.642	1.965	5.42	1.966	0.02	1.63063912	0.53003984
Infliximab	Liver abscess	Hepatobiliary and spleen infections	Infections - pathogen class unspecified	Infec	1968-2006	16	272	22486	2983381	2.981	1.956	4.392	3.822	30.914	3.824	2.697e-8	2.41849844	1.09225881
Infliximab	Liver disorder	Hepatic and hepatobiliary disorders NEC	Hepatic and hepatobiliary disorders	Hepat	1968-2006	84	5887	22418	2977766	0.94	0.783	1.12	0.945	0.266	0.944	0.606	0.88174494	-0.0618754
Infliximab	Liver function test abnormal	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	182	16339	22320	2967314	1.024	0.905	1.155	1.028	0.141	1.029	0.707	0.53502848	0.02371653
Infliximab	Liver tenderness	Hepatobiliary signs and symptoms	Hepatic and hepatobiliary disorders	Hepat	1968-2006	1	334	22501	2983319	0.501	0.116	1.563	0.519	0.449	0.519	0.503	-0.8214758	-0.6911492
Infliximab	Liver transplant	Hepatic therapeutic procedures	Hepatobiliary therapeutic procedures	Surg	1968-2006	11	645	22491	2983008	1.031	0.62	1.632	1.098	0.093	1.098	0.76	1.01056447	0.03052921
Infliximab	Lobar pneumonia	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	57	783	22445	2982870	3.894	3.12	4.814	4.518	140.829	4.528	1.754e-32	2.98130452	1.35943691
Infliximab	Local reaction	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	65	22501	2983588	0.777	0.18	2.426	1.19	0.03	1.19	0.863	0.40991926	-0.2523149
Infliximab	Local swelling	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	7	816	22495	2982837	0.466	0.247	0.817	0.46	4.355	0.46	0.037	0.14872435	-0.7635696
Infliximab	Localised infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	28	820	22474	2982833	1.664	1.211	2.241	1.783	9.203	1.784	0.002	1.96948241	0.50922434
Infliximab	Localised oedema	Oedema NEC	General system disorders NEC	Genrl	1968-2006	7	667	22495	2982986	0.626	0.332	1.097	0.639	1.411	0.638	0.235	0.39307255	-0.4684049
Infliximab	Locked-in syndrome	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	67	22501	2983586	0.7	0.162	2.184	0.942	0.003	0.942	0.953	0.39553403	-0.3566749
Infliximab	Loss of consciousness	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	174	17782	22328	2965871	0.632	0.557	0.715	0.628	38.405	0.625	5.747e-10	0.35059826	-0.4588659
Infliximab	Loss of control of legs	Gait disturbances	General system disorders NEC	Genrl	1968-2006	2	178	22500	2983475	0.702	0.228	1.76	0.81	0.089	0.81	0.766	0.34300056	-0.3538219
Infliximab	Loss of employment	Employment issues	Economic and housing issues	SocCi	1968-2006	1	318	22501	2983335	0.214	0.049	0.669	0.163	4.23	0.163	0.04	-0.7713472	-1.5417793
Infliximab	Low cardiac output syndrome	Heart failures NEC	Heart failures	Card	1968-2006	1	93	22501	2983560	0.686	0.159	2.141	0.905	0.01	0.905	0.921	0.22051265	-0.3768777
Infliximab	Low density lipoprotein increased	Cholesterol analyses	Lipid analyses	Inv	1968-2006	8	1108	22494	2982545	0.474	0.261	0.804	0.47	4.738	0.47	0.03	-0.0669722	-0.746548
Infliximab	Lower extremity mass	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	1	36	22501	2983617	0.823	0.19	2.569	1.376	0.098	1.376	0.754	0.63643321	-0.1947991
Infliximab	Lower gastrointestinal haemorrhage	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	6	383	22496	2983270	0.796	0.402	1.449	0.847	0.163	0.847	0.686	0.82850311	-0.2281561
Infliximab	Lower limb fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	10	822	22492	2982831	0.713	0.419	1.152	0.729	0.98	0.729	0.322	0.59464292	-0.3382739
Infliximab	Lower respiratory tract infection	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	64	1393	22438	2982260	3.202	2.598	3.912	3.567	108.722	3.575	1.868e-25	2.43722468	1.16377561
Infliximab	Lower respiratory tract inflammation	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	3	14	22499	2983639	2.463	0.948	5.544	11.63	21.869	11.63	2.919e-6	1.81634422	0.90138012
Infliximab	Lumbar hernia	Abdominal cavity hernias NEC	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	1	11	22501	2983642	1.09	0.252	3.407	3.609	1.831	3.609	0.176	0.86505951	0.0861777
Infliximab	Lumbar puncture abnormal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	3	70	22499	2983583	1.674	0.65	3.705	3.174	4.2	3.174	0.04	1.36018652	0.51521597
Infliximab	Lumbar spinal stenosis	Spine and neck deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	4	243	22498	2983410	1.058	0.462	2.149	1.282	0.235	1.282	0.628	0.80058056	0.05638033
Infliximab	Lumbar vertebral fracture	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	6	192	22496	2983461	1.334	0.673	2.43	1.624	1.364	1.624	0.243	1.48486581	0.28818195
Infliximab	Lung abscess	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	20	236	22482	2983417	4.098	2.809	5.822	5.72	67.835	5.724	1.777e-16	2.83725212	1.41049905
Infliximab	Lung adenocarcinoma	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	29	203	22473	2983450	5.538	4.034	7.494	8.085	147.15	8.094	7.276e-34	3.44356823	1.71163342
Infliximab	Lung adenocarcinoma metastatic	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	12	22500	2983641	1.875	0.605	4.748	10.287	13.193	10.287	0.000281	1.43033808	0.62860866
Infliximab	Lung adenocarcinoma stage I	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	2	22501	2983651	1.333	0.306	4.212	36.62	20.644	36.62	0.00000553	0.95711984	0.28743204
Infliximab	Lung adenocarcinoma stage IV	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	29	22501	2983624	0.926	0.214	2.891	1.947	0.423	1.947	0.515	0.69688322	-0.076881
Infliximab	Lung cancer metastatic	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	26	192	22476	2983461	4.928	3.535	6.742	7.039	112.485	7.05	2.797e-26	3.34790255	1.59493323
Infliximab	Lung carcinoma cell type unspecified recurrent	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	37	22500	2983616	1.429	0.463	3.587	3.256	2.879	3.256	0.09	1.20457957	0.3569749
Infliximab	Lung carcinoma cell type unspecified stage I	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	8	22501	2983645	1.216	0.281	3.812	8.414	5.185	8.414	0.023	0.89509832	0.19556678
Infliximab	Lung carcinoma cell type unspecified stage II	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	1	22501	2983652	1.349	0.309	4.272	109.237	27.662	109.237	1.445e-7	0.967721	0.29936358
Infliximab	Lung carcinoma cell type unspecified stage IV	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	10	105	22492	2983548	3.332	1.954	5.398	5.363	31.587	5.369	1.907e-8	2.55260785	1.20357272
Infliximab	Lung consolidation	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	15	485	22487	2983168	1.778	1.151	2.65	2.018	7.359	2.019	0.007	1.74323054	0.57548914
Infliximab	Lung cyst benign	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	1	13	22501	2983640	1.037	0.24	3.239	3.016	1.193	3.016	0.275	0.84537553	0.03633193
Infliximab	Lung disorder	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	196	9204	22306	2974449	2.839	2.521	3.188	3.007	246.502	3.028	0	1.4496727	1.04345188
Infliximab	Lung hyperinflation	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	3	49	22499	2983604	1.797	0.698	3.978	3.737	5.615	3.737	0.018	1.51484391	0.58611861
Infliximab	Lung infection	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	52	827	22450	2982826	2.949	2.338	3.68	3.301	76.644	3.308	2.047e-18	2.79455957	1.08146613
Infliximab	Lung infection pseudomonal	Pseudomonal infections	Bacterial infectious disorders	Infec	1968-2006	20	239	22482	2983414	4.091	2.804	5.812	5.733	67.602	5.737	2.001e-16	2.82618406	1.40878944
Infliximab	Lung infiltration	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	205	4114	22297	2979539	3.492	3.109	3.91	3.779	385.395	3.81	0	2.61496037	1.25047464
Infliximab	Lung injury	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	9	263	22493	2983390	1.698	0.969	2.807	2.056	4.658	2.057	0.031	1.70878692	0.52945109
Infliximab	Lung neoplasm	Respiratory tract and pleural neoplasms malignancy unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	97	834	22405	2982819	4.981	4.203	5.868	5.946	342.64	5.972	0	3.6090956	1.60563067
Infliximab	Lung neoplasm malignant	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	161	3136	22341	2980517	4.7	4.122	5.34	5.355	503.5	5.393	0	2.64497082	1.54756251
Infliximab	Lung operation	Bronchial and pulmonary therapeutic procedures	Respiratory tract therapeutic procedures	Surg	1968-2006	2	33	22500	2983620	1.555	0.504	3.908	4.353	4.492	4.353	0.034	1.23841037	0.44147555
Infliximab	Lung squamous cell carcinoma stage II	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.27	0.293	3.992	16.929	8.966	16.929	0.003	0.946596	0.2390169
Infliximab	Lung squamous cell carcinoma stage III	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	8	22501	2983645	1.19	0.275	3.726	6.782	4.077	6.782	0.043	0.89509832	0.17395331
Infliximab	Lung squamous cell carcinoma stage IV	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	17	22501	2983636	1.104	0.255	3.452	4.035	2.031	4.035	0.154	0.80679534	0.09893995
Infliximab	Lung squamous cell carcinoma stage unspecified	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	23	87	22479	2983566	9.978	6.153	15.562	16.025	241.931	16.042	0	3.7074567	2.30038267
Infliximab	Lung transplant	Bronchial and pulmonary therapeutic procedures	Respiratory tract therapeutic procedures	Surg	1968-2006	1	57	22501	2983596	0.704	0.163	2.198	0.955	0.002	0.955	0.964	0.46893872	-0.3509769
Infliximab	Lupus nephritis	Nephritis NEC	Nephropathies	Renal	1968-2006	5	75	22497	2983578	2.33	1.104	4.458	4.257	11.388	4.257	0.001	1.89707354	0.84586827
Infliximab	Lupus pneumonitis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	1	9	22501	2983644	1.22	0.282	3.826	8.218	5.341	8.218	0.021	0.88501574	0.19885086
Infliximab	Lupus-like syndrome	Lupus erythematosus (incl subtypes)	Connective tissue disorders (excl congenital)	Musc	1968-2006	410	383	22092	2983270	22.851	21.053	24.768	55.219	8859.8	56.368	0	5.87786979	3.12899488
Infliximab	Lyme disease	Borrelial infections	Bacterial infectious disorders	Infec	1968-2006	5	159	22497	2983494	1.45	0.688	2.77	1.911	2.043	1.911	0.153	1.4185613	0.37156356
Infliximab	Lymph gland infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	2	16	22500	2983637	1.639	0.531	4.122	5.474	5.972	5.474	0.015	1.3917579	0.4940863
Infliximab	Lymph node cancer metastatic	Lymphomas unspecified NEC	Lymphomas NEC	Neopl	1968-2006	1	18	22501	2983635	1.034	0.239	3.231	2.975	1.159	2.975	0.282	0.79730935	0.03343478
Infliximab	Lymph node pain	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	1	108	22501	2983545	0.612	0.142	1.912	0.729	0.101	0.729	0.751	0.12842453	-0.491023
Infliximab	Lymph node tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	51	35	22451	2983618	29.556	23.324	37.037	88.673	1490.698	88.914	0	4.97258942	3.38628677
Infliximab	Lymphadenitis	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	18	239	22484	2983414	3.746	2.517	5.414	5.107	53.471	5.111	2.624e-13	2.68916278	1.3206886
Infliximab	Lymphadenopathy	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	165	7355	22337	2976298	2.439	2.143	2.766	2.568	148.488	2.581	3.711e-34	1.52043956	0.89158812
Infliximab	Lymphadenopathy mediastinal	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	11	161	22491	2983492	3.293	1.98	5.224	4.936	31.656	4.939	1.84e-8	2.38028847	1.191799
Infliximab	Lymphangioma	Lymphatic system disorders congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	2	20	22500	2983633	1.685	0.545	4.241	5.584	6.925	5.584	0.008	1.3541825	0.52176556
Infliximab	Lymphangiopathy	Lymphangiopathies	Lymphatic vessel disorders	Vasc	1968-2006	1	24	22501	2983629	1.141	0.264	3.57	4.846	2.707	4.846	0.1	0.74166694	0.13190507
Infliximab	Lymphangiosarcoma	Lymphangiosarcomas	Soft tissue sarcomas	Neopl	1968-2006	1	1	22501	2983652	1.363	0.311	4.326	2954.316	37.669	2954.316	8.384e-10	0.967721	0.30968815
Infliximab	Lymphangiosis carcinomatosa	Metastases to specified sites	Metastases	Neopl	1968-2006	3	187	22499	2983466	0.862	0.335	1.906	1.015	0.001	1.015	0.979	0.71274679	-0.1485
Infliximab	Lymphangitis	Vascular infections	Infections - pathogen class unspecified	Infec	1968-2006	5	208	22497	2983445	1.682	0.797	3.213	2.402	3.808	2.403	0.051	1.19863733	0.51998356
Infliximab	Lymphocyte count	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	4	53	22498	2983600	1.808	0.789	3.676	3.022	5.089	3.025	0.024	1.79841737	0.59222126
Infliximab	Lymphocyte count abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	43	22501	2983610	0.805	0.186	2.514	1.298	0.067	1.298	0.796	0.5784143	-0.216913
Infliximab	Lymphocyte count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	21	761	22481	2982892	1.534	1.063	2.157	1.649	5.202	1.65	0.023	1.67138022	0.4278787
Infliximab	Lymphocyte count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	450	22501	2983203	0.19	0.044	0.593	0.141	5.133	0.141	0.023	-1.1406277	-1.6607312
Infliximab	Lymphocyte morphology abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	4	175	22498	2983478	1.22	0.533	2.479	1.571	0.796	1.571	0.372	1.08457504	0.19885086
Infliximab	Lymphocyte percentage decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	11	235	22491	2983418	2.292	1.379	3.628	2.945	13.133	2.947	0.0002901	2.06741327	0.8294248
Infliximab	Lymphocyte percentage increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	116	22500	2983537	0.768	0.249	1.926	0.926	0.011	0.926	0.915	0.66082953	-0.2639655
Infliximab	Lymphocyte stimulation test positive	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	449	22499	2983204	0.377	0.147	0.834	0.361	3.351	0.36	0.067	-0.1430932	-0.9755101
Infliximab	Lymphocytic infiltration	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	8	113	22494	2983540	2.439	1.346	4.143	3.589	13.603	3.59	0.0002258	2.22869115	0.89158812
Infliximab	Lymphocytic leukaemia	Leukaemias lymphocytic NEC	Leukaemias	Neopl	1968-2006	4	50	22498	2983603	2.367	1.031	4.828	5.668	13.085	5.668	0.0002976	1.82130768	0.86162333
Infliximab	Lymphocytic lymphoma	Lymphomas unspecified NEC	Lymphomas NEC	Neopl	1968-2006	3	10	22499	2983643	2.545	0.977	5.772	12.12	25.662	12.122	4.068e-7	1.85518405	0.93413065
Infliximab	Lymphocytosis	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	15	838	22487	2982815	2.466	1.596	3.675	3.012	19.04	3.013	0.0000128	1.10416349	0.9025974
Infliximab	Lymphoedema	Lymphoedemas	Lymphatic vessel disorders	Vasc	1968-2006	4	523	22498	2983130	0.558	0.244	1.134	0.57	1.285	0.57	0.257	0.0049363	-0.5833963
Infliximab	Lymphohistiocytosis	Histiocytoses	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	3	17	22499	2983636	2.321	0.897	5.184	8.202	16.579	8.202	0.00004666	1.78788545	0.84199813
Infliximab	Lymphoid tissue hyperplasia	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	3	50	22499	2983603	1.706	0.662	3.775	3.33	4.539	3.33	0.033	1.50709096	0.53415145
Infliximab	Lymphoma	Lymphomas unspecified NEC	Lymphomas NEC	Neopl	1968-2006	181	1530	22321	2982123	6.511	5.75	7.352	7.815	908.506	7.871	0	3.70884399	1.87349305
Infliximab	Lymphoma cutis	B-cell lymphomas NEC	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	4	22501	2983649	1.272	0.293	3.998	15.617	9.064	15.617	0.003	0.93614837	0.24059046
Infliximab	Lymphomatoid papulosis	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	5	15	22497	2983638	4.881	1.966	18.534	24.272	80.134	24.304	3.498e-19	2.37284808	1.58535012
Infliximab	Lymphopenia	Leukopenias NEC	White blood cell disorders	Blood	1968-2006	37	917	22465	2982736	2.534	1.923	3.289	2.795	40.591	2.799	1.877e-10	2.21144007	0.92979908
Infliximab	Lymphoplasmacytoid lymphoma/immunocytoma	Lymphoplasmacytoid lymphomas/immunocytomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	12	22501	2983641	1.13	0.261	3.533	4.784	2.499	4.784	0.114	0.85518395	0.12221763
Infliximab	Lymphoproliferative disorder	Lymphoproliferative disorders NEC (excl leukaemias and lymphomas)	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	13	457	22489	2983196	1.638	1.027	2.507	1.859	4.933	1.86	0.026	1.62057921	0.49347599
Infliximab	Macrocytosis	Red blood cell abnormal findings NEC	Red blood cell disorders	Blood	1968-2006	3	267	22499	2983386	0.663	0.257	1.464	0.714	0.34	0.714	0.56	0.3939894	-0.4109803
Infliximab	Macroglossia	Tongue disorders congenital	Gastrointestinal tract disorders congenital	Cong	1968-2006	2	57	22500	2983596	1.349	0.437	3.384	2.779	2.107	2.779	0.147	1.04639056	0.29936358
Infliximab	Macrophage activation	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	11	22501	2983642	1.094	0.253	3.419	3.782	1.887	3.782	0.17	0.86505951	0.0898407
Infliximab	Macular degeneration	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	10	1034	22492	2982619	0.605	0.355	0.977	0.61	2.46	0.61	0.117	0.30818721	-0.5025268
Infliximab	Macular hole	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	2	52	22500	2983601	1.17	0.379	2.934	2.001	0.92	2.002	0.338	1.0843418	0.15700375
Infliximab	Macular oedema	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	2	607	22500	2983046	0.278	0.09	0.698	0.25	4.5	0.25	0.034	-0.9008792	-1.2801342
Infliximab	Maculopathy	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	4	329	22498	2983324	0.731	0.319	1.485	0.788	0.223	0.788	0.637	0.50662499	-0.3133418
Infliximab	Madarosis	Lid, lash and lacrimal structural disorders	Anterior eye structural change, deposit and degeneration	Eye	1968-2006	1	98	22501	2983555	0.588	0.136	1.836	0.675	0.153	0.674	0.696	0.18915904	-0.5310283
Infliximab	Major depression	Depressive disorders	Depressed mood disorders and disturbances	Psych	1968-2006	3	3901	22499	2979752	0.296	0.115	0.653	0.275	5.702	0.275	0.017	-2.9302839	-1.2173958
Infliximab	Malabsorption	Malabsorption syndromes	Malabsorption conditions	Gastr	1968-2006	4	491	22498	2983162	0.783	0.342	1.591	0.86	0.09	0.86	0.765	0.07658699	-0.2446226
Infliximab	Malaise	Asthenic conditions	General system disorders NEC	Genrl	1968-2006	328	32522	22174	2951131	0.992	0.905	1.085	0.993	0.015	0.993	0.902	0.38755448	-0.0080322
Infliximab	Malaria	Plasmodia infections	Protozoal infectious disorders	Infec	1968-2006	1	169	22501	2983484	0.454	0.105	1.418	0.441	0.69	0.441	0.406	-0.1952029	-0.7896581
Infliximab	Malignant anorectal neoplasm	Rectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	4	22501	2983649	1.2	0.277	3.761	7.815	4.535	7.816	0.033	0.93614837	0.18232156
Infliximab	Malignant ascites	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	5	61	22497	2983592	2.417	1.145	4.628	4.601	12.816	4.602	0.0003436	1.99488241	0.8825271
Infliximab	Malignant fibrous histiocytoma	Fibrous histiocytomas malignant	Soft tissue neoplasms malignant and unspecified (excl sarcomas)	Neopl	1968-2006	2	18	22500	2983635	1.786	0.577	4.505	7.323	9.657	7.324	0.002	1.37284789	0.57997848
Infliximab	Malignant histiocytosis	Histiocytoses	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	1	40	22501	2983613	0.889	0.206	2.775	1.702	0.274	1.702	0.6	0.60299444	-0.117658
Infliximab	Malignant hydatidiform mole	Extragonadal primary germ cell neoplasms	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.345	0.308	4.256	1075.772	51.692	1083.348	6.493e-13	0.97840063	0.29639401
Infliximab	Malignant melanoma	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	116	798	22386	2982855	7.996	6.808	9.37	10.328	783.325	10.377	0	3.88799025	2.07894142
Infliximab	Malignant melanoma of eyelid	Ocular melanomas	Ocular neoplasms	Neopl	1968-2006	1	0	22501	2983653	1.364	0.311	4.328	1084.324	71.361	1091.976	2.975e-17	0.97840063	0.31042156
Infliximab	Malignant melanoma of sites other than skin	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	1	8	22501	2983645	1.247	0.288	3.914	10.874	6.936	10.874	0.008	0.89509832	0.22074067
Infliximab	Malignant melanoma stage I	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	3	4	22499	2983649	3.594	1.175	22.092	54.681	86.427	54.681	1.45e-20	1.91547742	1.27926579
Infliximab	Malignant melanoma stage II	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	2	9	22500	2983644	1.928	0.621	4.898	14.321	16.023	14.333	0.00006259	1.45996566	0.6564832
Infliximab	Malignant melanoma stage IV	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	3	66	22499	2983587	1.555	0.604	3.44	2.664	3.069	2.665	0.08	1.38839518	0.44147555
Infliximab	Malignant neoplasm of ampulla of Vater	Hepatobiliary neoplasms malignant NEC	Hepatobiliary neoplasms malignant and unspecified	Neopl	1968-2006	1	11	22501	2983642	1.205	0.278	3.775	7.22	4.647	7.221	0.031	0.86505951	0.18647957
Infliximab	Malignant neoplasm of eye	Ocular neoplasms malignant (excl melanomas)	Ocular neoplasms	Neopl	1968-2006	1	12	22501	2983641	1.209	0.279	3.79	6.965	4.813	6.966	0.028	0.85518395	0.18979357
Infliximab	Malignant neoplasm of islets of Langerhans	Islet cell neoplasms and APUDoma NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	7	22501	2983646	1.224	0.282	3.837	9.642	5.573	9.642	0.018	0.90525186	0.20212418
Infliximab	Malignant neoplasm of thorax	Mediastinal neoplasms malignant	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.316	0.302	4.15	36.539	15.831	36.539	0.00006926	0.946596	0.27459683
Infliximab	Malignant neoplasm progression	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	12	4888	22490	2978765	0.132	0.081	0.205	0.126	73.64	0.125	9.373e-18	-1.5484152	-2.0249534
Infliximab	Malignant omentum neoplasm	Gastrointestinal neoplasms malignant NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	5	22501	2983648	1.253	0.289	3.933	12.059	7.389	12.059	0.007	0.92577585	0.22554068
Infliximab	Malignant palate neoplasm	Lip and oral cavity neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	4	22500	2983649	2.209	0.69	5.9	40.591	45.095	40.591	1.877e-11	1.51073838	0.79253992
Infliximab	Malignant pleural effusion	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	5	145	22497	2983508	1.519	0.72	2.901	2.047	2.519	2.047	0.113	1.48808616	0.41805222
Infliximab	Malignant respiratory tract neoplasm	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	3	3	22499	2983650	3.163	1.124	10.808	58.516	63.672	58.542	1.47e-15	1.9257759	1.15152094
Infliximab	Malignant soft tissue neoplasm	Soft tissue neoplasms malignant and unspecified NEC (excl sarcomas)	Soft tissue neoplasms malignant and unspecified (excl sarcomas)	Neopl	1968-2006	1	7	22501	2983646	1.175	0.271	3.677	6.003	3.611	6.003	0.057	0.90525186	0.16126815
Infliximab	Mallory-Weiss syndrome	Gastric and oesophageal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	7	318	22495	2983335	1.256	0.666	2.202	1.452	0.965	1.452	0.326	1.209652	0.22793207
Infliximab	Malnutrition	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	34	1071	22468	2982582	1.905	1.428	2.499	2.047	17.413	2.048	0.00003007	1.90515843	0.64448201
Infliximab	Mammary duct ectasia	Breast disorders NEC	Breast disorders	Repro	1968-2006	2	5	22500	2983648	2.129	0.674	5.555	31.529	33.799	31.542	6.111e-9	1.50043989	0.75565239
Infliximab	Mammogram abnormal	Reproductive organ and breast imaging procedures	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	71	22501	2983582	0.635	0.147	1.982	0.775	0.063	0.775	0.802	0.36718681	-0.4541303
Infliximab	Mania	Mood alterations with manic symptoms	Manic and bipolar mood disorders and disturbances	Psych	1968-2006	6	4877	22496	2978776	0.151	0.076	0.275	0.14	31.577	0.14	1.917e-8	-2.4366139	-1.8904754
Infliximab	Mantle cell lymphoma	Mantle cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	5	42	22497	2983611	3.116	1.467	6.051	8.316	28.2	8.32	1.094e-7	2.13920891	1.13655013
Infliximab	Mantle cell lymphoma stage III	Mantle cell lymphomas	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	0	22501	2983653	1.381	0.314	4.399	1090.959	100.956	1098.695	9.406e-24	0.97840063	0.32280787
Infliximab	Marrow hyperplasia	Haematologic neoplasms NEC	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	4	459	22498	2983194	0.836	0.365	1.698	0.934	0.018	0.933	0.892	0.15198133	-0.1791267
Infliximab	Mass	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	29	801	22473	2982852	1.92	1.406	2.574	2.095	15.663	2.097	0.00007571	2.04510209	0.65232519
Infliximab	Mass excision	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	20	22501	2983633	1.106	0.256	3.458	3.986	2.063	3.986	0.151	0.77852244	0.1007499
Infliximab	Mastectomy	Mastectomies	Breast therapeutic procedures	Surg	1968-2006	2	178	22500	2983475	0.576	0.187	1.444	0.614	0.489	0.614	0.484	0.34300056	-0.5516476
Infliximab	Mastitis	Breast infections	Infections - pathogen class unspecified	Infec	1968-2006	2	351	22500	2983302	0.63	0.204	1.581	0.693	0.269	0.693	0.604	-0.2909016	-0.4620355
Infliximab	Mastoidectomy	Mastoid therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	1	2	22501	2983651	1.32	0.303	4.166	28.423	16.927	28.423	0.00003884	0.95711984	0.27763174
Infliximab	Mastoiditis	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	4	99	22498	2983554	1.76	0.768	3.578	2.847	4.573	2.847	0.032	1.48648636	0.56531381
Infliximab	Maternal drugs affecting foetus	Injuries due to in utero exposure	Chemical injury and poisoning	Inj&P	1968-2006	69	5273	22433	2978380	0.513	0.419	0.622	0.506	33.465	0.501	7.256e-9	0.75881437	-0.6674794
Infliximab	Mean cell haemoglobin	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	21	22501	2983632	0.994	0.23	3.103	2.46	0.819	2.46	0.365	0.76921993	-0.0060181
Infliximab	Mean cell haemoglobin concentration	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	10	22501	2983643	1.078	0.249	3.369	3.562	1.67	3.562	0.196	0.87500312	0.07510747
Infliximab	Mean cell haemoglobin concentration decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	49	22501	2983604	0.749	0.173	2.338	1.092	0.008	1.092	0.93	0.53047566	-0.2890163
Infliximab	Mean cell haemoglobin decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	82	22499	2983571	1.387	0.539	3.068	2.187	1.809	2.187	0.179	1.27872578	0.32714314
Infliximab	Mean cell haemoglobin increased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	99	22500	2983554	0.883	0.286	2.213	1.157	0.042	1.157	0.837	0.76176862	-0.1244301
Infliximab	Mean cell volume	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	28	22501	2983625	0.836	0.193	2.611	1.434	0.126	1.434	0.723	0.70572945	-0.1791267
Infliximab	Mean cell volume abnormal	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	163	22500	2983490	0.941	0.305	2.359	1.292	0.129	1.292	0.72	0.4137203	-0.0608121
Infliximab	Mean cell volume decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	4	131	22498	2983522	1.4	0.611	2.844	1.95	1.737	1.95	0.188	1.30345829	0.33647224
Infliximab	Mean cell volume increased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	288	22500	2983365	0.461	0.149	1.155	0.459	1.282	0.459	0.258	-0.0908353	-0.7743572
Infliximab	Measles	Rubeola viral infections	Viral infectious disorders	Infec	1968-2006	1	59	22501	2983594	0.745	0.172	2.325	1.08	0.006	1.08	0.94	0.453956	-0.2943711
Infliximab	Mechanical complication of implant	Implant and catheter site reactions	Administration site reactions	Genrl	1968-2006	1	111	22501	2983542	0.622	0.144	1.94	0.744	0.084	0.744	0.772	0.11069173	-0.4748152
Infliximab	Mediastinal abscess	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	2	8	22500	2983645	1.932	0.622	4.908	14.894	16.26	14.894	0.00005521	1.46997828	0.65855574
Infliximab	Mediastinal biopsy abnormal	Respiratory tract and thoracic histopathology procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	0	22501	2983653	1.371	0.313	4.358	1087.21	81.81	1094.875	1.498e-19	0.97840063	0.3155404
Infliximab	Mediastinal haematoma	Mediastinal disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	1	16	22501	2983637	1.068	0.247	3.339	3.408	1.537	3.408	0.215	0.81634411	0.06578774
Infliximab	Mediastinal mass	Mediastinal disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	3	35	22499	2983618	1.885	0.732	4.175	4.395	6.846	4.396	0.009	1.6280008	0.63392782
Infliximab	Mediastinitis	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	6	64	22496	2983589	3.134	1.576	5.758	7.203	26.358	7.204	2.836e-7	2.18864657	1.14231014
Infliximab	Mediastinoscopy abnormal	Respiratory tract and thoracic imaging procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	1	22501	2983652	1.37	0.312	4.353	60.258	43.651	60.258	3.926e-11	0.967721	0.31481074
Infliximab	Medical device complication	Device related complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	9	1103	22493	2982550	0.467	0.266	0.772	0.463	5.58	0.462	0.018	0.0896588	-0.761426
Infliximab	Medical device removal	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	26	22501	2983627	0.941	0.218	2.938	2.036	0.497	2.036	0.481	0.72358631	-0.0608121
Infliximab	Medication error	Medication errors NEC	Medication errors	Inj&P	1968-2006	38	22673	22464	2960980	0.099	0.076	0.129	0.096	340.306	0.094	0	-2.154284	-2.3126354
Infliximab	Megacolon	Non-mechanical ileus	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	6	338	22496	2983315	1.323	0.668	2.41	1.599	1.299	1.6	0.254	0.95843034	0.27990189
Infliximab	Melaena	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	23	7749	22479	2975904	0.399	0.281	0.553	0.392	21.545	0.391	3.456e-6	-1.3165637	-0.9187939
Infliximab	Melanocytic naevus	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	9	243	22493	2983410	1.929	1.101	3.189	2.463	7.211	2.463	0.007	1.78175001	0.65700173
Infliximab	Melanosis coli	Gastrointestinal mucosal dystrophies and secretion disorders	Gastrointestinal conditions NEC	Gastr	1968-2006	2	53	22500	2983600	1.239	0.401	3.106	2.269	1.306	2.269	0.253	1.07667128	0.2143046
Infliximab	Melkersson-Rosenthal syndrome	Skin and subcutaneous tissue disorders congenital NEC	Skin and subcutaneous tissue disorders congenital	Cong	1968-2006	1	5	22501	2983648	1.24	0.286	3.891	11.292	6.504	11.292	0.011	0.92577585	0.21511138
Infliximab	Memory impairment	Memory loss (excl dementia)	Mental impairment disorders	Nerv	1968-2006	53	6565	22449	2977088	0.454	0.361	0.565	0.448	35.886	0.446	2.092e-9	0.08158058	-0.7896581
Infliximab	Menieres disease	Inner ear disorders NEC	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	7	194	22495	2983459	1.739	0.922	3.048	2.261	4.605	2.262	0.032	1.66451611	0.55331024
Infliximab	Meningeal disorder	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	7	145	22495	2983508	2.329	1.235	4.085	3.476	11.542	3.477	0.001	1.8929846	0.84543899
Infliximab	Meningeal neoplasm	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	24	22501	2983629	1.057	0.244	3.302	3.294	1.391	3.294	0.238	0.74166694	0.05543471
Infliximab	Meningioma	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	17	303	22485	2983350	2.472	1.643	3.602	3.009	20.934	3.012	4.753e-6	2.39539871	0.90502754
Infliximab	Meningism	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	4	397	22498	2983256	1.354	0.591	2.751	1.849	1.467	1.85	0.226	0.31031675	0.30306317
Infliximab	Meningitis	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	34	2611	22468	2981042	2.143	1.607	2.811	2.344	24.696	2.347	6.712e-7	0.73876339	0.76220672
Infliximab	Meningitis aseptic	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	18	562	22484	2983091	1.753	1.179	2.529	1.946	7.952	1.947	0.005	1.81957621	0.56132861
Infliximab	Meningitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	5	154	22497	2983499	1.484	0.704	2.835	1.981	2.272	1.981	0.132	1.44300885	0.39474114
Infliximab	Meningitis candida	Candida infections	Fungal infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.366	0.312	4.334	121.975	39.077	121.975	4.074e-10	0.967721	0.31188676
Infliximab	Meningitis coccidioides	Coccidioides infections	Fungal infectious disorders	Infec	1968-2006	1	4	22501	2983649	1.305	0.3	4.112	17.994	13.578	17.994	0.0002288	0.93614837	0.26620304
Infliximab	Meningitis cryptococcal	Cryptococcal infections	Fungal infectious disorders	Infec	1968-2006	9	150	22493	2983503	2.788	1.59	4.614	4.155	19.904	4.157	8.142e-6	2.17997551	1.02532449
Infliximab	Meningitis haemophilus	Haemophilus infections	Bacterial infectious disorders	Infec	1968-2006	3	7	22499	2983646	2.926	1.081	7.341	27.532	48.117	27.532	4.016e-12	1.88501581	1.0736363
Infliximab	Meningitis herpes	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	3	36	22499	2983617	2.128	0.825	4.729	6.539	11.305	6.54	0.001	1.61961718	0.75518257
Infliximab	Meningitis listeria	Listeria infections	Bacterial infectious disorders	Infec	1968-2006	42	30	22460	2983623	33.468	25.759	42.898	118.696	1411.202	119.039	0	4.7934586	3.51058976
Infliximab	Meningitis meningococcal	Neisseria infections	Bacterial infectious disorders	Infec	1968-2006	2	20	22500	2983633	1.699	0.55	4.278	6.053	7.254	6.053	0.007	1.3541825	0.53003984
Infliximab	Meningitis pneumococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	6	64	22496	2983589	3.091	1.555	5.674	6.485	25.344	6.486	4.796e-7	2.18864657	1.12849466
Infliximab	Meningitis streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	2	19	22500	2983634	1.771	0.572	4.466	7.782	9.194	7.783	0.002	1.36348501	0.57154436
Infliximab	Meningitis tuberculous	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	20	26	22482	2983627	23.877	16.2	34.159	46.246	482.337	46.295	0	3.95457696	3.17291565
Infliximab	Meningitis viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	13	227	22489	2983426	2.518	1.578	3.855	3.276	18.427	3.278	0.00001765	2.31279501	0.92346494
Infliximab	Meningococcal infection	Neisseria infections	Bacterial infectious disorders	Infec	1968-2006	1	20	22501	2983633	1.057	0.244	3.303	3.095	1.394	3.095	0.238	0.77852244	0.05543471
Infliximab	Meningococcal sepsis	Neisseria infections	Bacterial infectious disorders	Infec	1968-2006	3	21	22499	2983632	2.395	0.924	5.369	10.206	19.094	10.207	0.00001244	1.75079308	0.87338323
Infliximab	Meningoencephalitis bacterial	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	8	22501	2983645	1.205	0.278	3.775	7.224	4.665	7.224	0.031	0.89509832	0.18647957
Infliximab	Meningoencephalitis herpetic	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	2	15	22500	2983638	1.784	0.576	4.5	7.34	9.624	7.34	0.002	1.40130667	0.57885803
Infliximab	Meningoradiculitis	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	7	22501	2983646	1.225	0.283	3.84	8.626	5.575	8.626	0.018	0.90525186	0.20294084
Infliximab	Meningorrhagia	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	1	45	22501	2983608	0.786	0.182	2.454	1.222	0.04	1.222	0.842	0.56225713	-0.2407985
Infliximab	Meniscus lesion	Limb injuries NEC (incl traumatic amputation)	Bone and joint injuries	Inj&P	1968-2006	3	333	22499	2983320	0.551	0.214	1.218	0.564	0.986	0.564	0.321	0.1754489	-0.5960205
Infliximab	Menometrorrhagia	Menstruation with increased bleeding	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	3	20966	22499	2962687	0.199	0.077	0.44	0.178	11.283	0.177	0.001	-5.3244222	-1.6144505
Infliximab	Menorrhagia	Menstruation with increased bleeding	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	13	6220	22489	2977433	0.283	0.177	0.433	0.274	24.975	0.273	5.807e-7	-1.7810781	-1.2623084
Infliximab	Menstrual disorder	Menstruation and uterine bleeding NEC	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	5	4133	22497	2979520	0.166	0.079	0.317	0.155	23.504	0.154	1.246e-6	-2.4267125	-1.7957675
Infliximab	Menstruation irregular	Menstruation and uterine bleeding NEC	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	7	1546	22495	2982107	0.349	0.185	0.612	0.338	8.994	0.338	0.003	-0.6697619	-1.0526834
Infliximab	Mental disorder	Mental disorders NEC	Psychiatric disorders NEC	Psych	1968-2006	11	3325	22491	2980328	0.224	0.135	0.354	0.215	31.448	0.215	2.049e-8	-1.1263138	-1.4961092
Infliximab	Mental impairment	Mental impairment (excl dementia and memory loss)	Mental impairment disorders	Nerv	1968-2006	20	3816	22482	2979837	0.483	0.331	0.685	0.478	11.266	0.478	0.001	-0.5134213	-0.7277386
Infliximab	Mental status changes	Mental disorders NEC	Psychiatric disorders NEC	Psych	1968-2006	40	3564	22462	2980089	0.584	0.448	0.751	0.579	12.036	0.579	0.001	0.53881654	-0.5378543
Infliximab	Mesenteric artery stenosis	Gastrointestinal vascular occlusion and infarction	Gastrointestinal vascular conditions	Gastr	1968-2006	1	21	22501	2983632	0.978	0.226	3.054	2.365	0.713	2.365	0.398	0.76921993	-0.0222456
Infliximab	Mesenteric fibrosis	Peritoneal and retroperitoneal fibrosis and adhesions	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	2	21	22500	2983632	1.961	0.63	4.993	12.975	17.932	12.975	0.0000229	1.34493959	0.67345455
Infliximab	Mesenteric occlusion	Gastrointestinal vascular occlusion and infarction	Gastrointestinal vascular conditions	Gastr	1968-2006	1	442	22501	2983211	0.425	0.098	1.326	0.401	0.887	0.401	0.346	-1.1207447	-0.8556661
Infliximab	Mesenteric panniculitis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	3	4	22499	2983649	3.821	1.196	26.73	97.191	96.819	97.191	7.596e-23	1.91547742	1.34051217
Infliximab	Mesenteric vascular insufficiency	Gastrointestinal vascular occlusion and infarction	Gastrointestinal vascular conditions	Gastr	1968-2006	3	36	22499	2983617	2.147	0.832	4.773	6.517	11.745	6.519	0.001	1.61961718	0.76407152
Infliximab	Mesenteric vein thrombosis	Gastrointestinal vascular occlusion and infarction	Gastrointestinal vascular conditions	Gastr	1968-2006	3	95	22499	2983558	1.222	0.475	2.702	1.74	0.899	1.74	0.343	1.19537591	0.20048886
Infliximab	Mesothelioma	Mesotheliomas malignant and unspecified	Mesotheliomas	Neopl	1968-2006	2	30	22500	2983623	1.425	0.462	3.576	3.215	2.834	3.215	0.092	1.26431441	0.35417181
Infliximab	Metabolic acidosis	Metabolic acidoses (excl diabetic acidoses)	Acid-base disorders	Metab	1968-2006	42	3678	22460	2979975	0.771	0.595	0.985	0.773	2.74	0.773	0.098	0.56337938	-0.2600669
Infliximab	Metabolic disorder	Metabolic disorders NEC	Metabolism disorders NEC	Metab	1968-2006	3	828	22499	2982825	0.248	0.096	0.547	0.226	7.905	0.226	0.005	-0.8632963	-1.3943265
Infliximab	Metabolic encephalopathy	Encephalopathies toxic and metabolic	Encephalopathies	Nerv	1968-2006	3	360	22499	2983293	0.546	0.212	1.207	0.561	1.023	0.561	0.312	0.09478321	-0.6051363
Infliximab	Metamorphopsia	Visual disorders NEC	Vision disorders	Eye	1968-2006	1	28	22501	2983625	1.046	0.242	3.268	3.13	1.269	3.13	0.26	0.70572945	0.04497337
Infliximab	Metamyelocyte count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	10	22501	2983643	1.132	0.262	3.54	4.381	2.549	4.381	0.11	0.87500312	0.12398598
Infliximab	Metaplasia	Trophic disorders	Tissue disorders NEC	Genrl	1968-2006	4	66	22498	2983587	1.974	0.861	4.016	3.586	6.946	3.586	0.008	1.70321941	0.68006194
Infliximab	Metastases to abdominal cavity	Metastases to specified sites	Metastases	Neopl	1968-2006	2	84	22500	2983569	1.098	0.356	2.754	1.732	0.591	1.732	0.442	0.85710281	0.09349034
Infliximab	Metastases to abdominal wall	Metastases to specified sites	Metastases	Neopl	1968-2006	1	8	22501	2983645	1.185	0.274	3.71	6.832	3.93	6.832	0.047	0.89509832	0.16974277
Infliximab	Metastases to adrenals	Metastases to specified sites	Metastases	Neopl	1968-2006	3	97	22499	2983556	1.271	0.494	2.811	1.869	1.135	1.869	0.287	1.18296967	0.23980399
Infliximab	Metastases to bladder	Metastases to specified sites	Metastases	Neopl	1968-2006	1	17	22501	2983636	1.092	0.252	3.412	3.879	1.839	3.879	0.175	0.80679534	0.08801088
Infliximab	Metastases to bone	Metastases to specified sites	Metastases	Neopl	1968-2006	20	951	22482	2982702	1.264	0.868	1.792	1.334	1.626	1.334	0.202	1.33343848	0.2342813
Infliximab	Metastases to bone marrow	Metastases to specified sites	Metastases	Neopl	1968-2006	1	57	22501	2983596	0.719	0.166	2.244	0.998	0	0.998	0.999	0.46893872	-0.3298939
Infliximab	Metastases to central nervous system	Metastases to specified sites	Metastases	Neopl	1968-2006	18	1074	22484	2982579	0.994	0.668	1.434	1.029	0.015	1.029	0.904	1.0390245	-0.0060181
Infliximab	Metastases to chest wall	Metastases to specified sites	Metastases	Neopl	1968-2006	1	31	22501	2983622	0.859	0.199	2.682	1.539	0.182	1.539	0.669	0.67935182	-0.1519864
Infliximab	Metastases to gallbladder	Metastases to specified sites	Metastases	Neopl	1968-2006	1	6	22501	2983647	1.22	0.282	3.823	8.17	5.336	8.17	0.021	0.91547736	0.19885086
Infliximab	Metastases to gastrointestinal tract	Metastases to specified sites	Metastases	Neopl	1968-2006	1	29	22501	2983624	0.876	0.203	2.734	1.609	0.231	1.609	0.63	0.69688322	-0.1323892
Infliximab	Metastases to kidney	Metastases to specified sites	Metastases	Neopl	1968-2006	1	60	22501	2983593	0.719	0.166	2.245	1	0	1	1	0.44652257	-0.3298939
Infliximab	Metastases to large intestine	Metastases to specified sites	Metastases	Neopl	1968-2006	2	27	22500	2983626	1.546	0.501	3.882	4.319	4.351	4.319	0.037	1.29069204	0.43567095
Infliximab	Metastases to liver	Metastases to specified sites	Metastases	Neopl	1968-2006	69	1659	22433	2981994	2.475	2.024	3.002	2.65	67.183	2.656	2.474e-16	2.31703873	0.9062404
Infliximab	Metastases to lung	Metastases to specified sites	Metastases	Neopl	1968-2006	31	917	22471	2982736	1.934	1.43	2.568	2.091	16.895	2.093	0.00003951	1.97149393	0.6595904
Infliximab	Metastases to lymph nodes	Metastases to specified sites	Metastases	Neopl	1968-2006	26	697	22476	2982956	2.187	1.573	2.977	2.433	20.887	2.434	4.873e-6	2.06296289	0.78253074
Infliximab	Metastases to meninges	Metastases to specified sites	Metastases	Neopl	1968-2006	1	93	22501	2983560	0.518	0.12	1.618	0.545	0.375	0.545	0.54	0.22051265	-0.65778
Infliximab	Metastases to ovary	Metastases to specified sites	Metastases	Neopl	1968-2006	2	18	22500	2983635	1.651	0.534	4.151	5.111	6.188	5.111	0.013	1.37284789	0.50138116
Infliximab	Metastases to peritoneum	Metastases to specified sites	Metastases	Neopl	1968-2006	10	92	22492	2983561	3.31	1.941	5.362	5.533	31.123	5.535	2.422e-8	2.63010229	1.19694819
Infliximab	Metastases to pleura	Metastases to specified sites	Metastases	Neopl	1968-2006	1	76	22501	2983577	0.616	0.142	1.922	0.731	0.095	0.731	0.758	0.33251843	-0.4845083
Infliximab	Metastases to rectum	Metastases to specified sites	Metastases	Neopl	1968-2006	1	5	22501	2983648	1.244	0.287	3.904	11.749	6.782	11.757	0.009	0.92577585	0.21833199
Infliximab	Metastases to small intestine	Metastases to specified sites	Metastases	Neopl	1968-2006	1	24	22501	2983629	1.019	0.236	3.182	2.715	1.013	2.715	0.314	0.74166694	0.01882175
Infliximab	Metastases to spine	Metastases to specified sites	Metastases	Neopl	1968-2006	11	255	22491	2983398	2.093	1.26	3.314	2.606	10.213	2.607	0.001	1.99332618	0.73859844
Infliximab	Metastases to spleen	Metastases to specified sites	Metastases	Neopl	1968-2006	2	44	22500	2983609	1.228	0.398	3.079	2.172	1.241	2.172	0.265	1.14721976	0.20538683
Infliximab	Metastases to stomach	Metastases to specified sites	Metastases	Neopl	1968-2006	1	20	22501	2983633	0.944	0.218	2.948	2.042	0.514	2.042	0.473	0.77852244	-0.0576291
Infliximab	Metastases to the mediastinum	Metastases to specified sites	Metastases	Neopl	1968-2006	1	34	22501	2983619	0.944	0.218	2.948	2.023	0.512	2.024	0.474	0.65344776	-0.0576291
Infliximab	Metastases to thyroid	Metastases to specified sites	Metastases	Neopl	1968-2006	1	4	22501	2983649	1.263	0.291	3.967	13.586	8.231	13.59	0.004	0.93614837	0.23348984
Infliximab	Metastasis	Metastases to unknown and unspecified sites	Metastases	Neopl	1968-2006	30	1062	22472	2982591	1.756	1.292	2.343	1.886	11.911	1.888	0.001	1.74529848	0.5630385
Infliximab	Metastatic bronchial carcinoma	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	17	22501	2983636	1.077	0.249	3.365	3.368	1.638	3.369	0.201	0.80679534	0.0741794
Infliximab	Metastatic malignant melanoma	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	8	145	22494	2983508	1.987	1.097	3.374	2.617	7.547	2.618	0.006	2.05786667	0.68662596
Infliximab	Metastatic neoplasm	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	37	505	22465	2983148	3.923	2.977	5.095	4.844	98.751	4.85	2.863e-23	2.89854871	1.36685667
Infliximab	Metastatic renal cell carcinoma	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	6	91	22496	2983562	2.54	1.281	4.633	4.388	14.471	4.391	0.0001423	2.0089748	0.93216408
Infliximab	Metastatic squamous cell carcinoma	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	2	12	22500	2983641	1.994	0.64	5.093	15.619	20.291	15.624	6.653e-6	1.43033808	0.69014267
Infliximab	Metatarsal excision	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	2	22501	2983651	1.351	0.309	4.278	178.545	28.621	178.545	8.804e-8	0.95711984	0.30084506
Infliximab	Methaemoglobinaemia	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	1	743	22501	2982910	0.222	0.051	0.693	0.17	3.976	0.17	0.046	-1.726887	-1.5050779
Infliximab	Methicillin-resistant staphylococcal aureus test	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	6	0	22496	2983653	22.603	4.67	52.585	4663.687	246.361	4697.274	0	2.73313089	3.11808264
Infliximab	Methicillin-resistant staphylococcal aureus test positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	8	38	22494	2983615	4.323	2.341	7.723	10.632	56.388	10.636	5.95e-14	2.73218302	1.46394961
Infliximab	Metrorrhagia	Menstruation with increased bleeding	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	5	8466	22497	2975187	0.029	0.014	0.055	0.026	190.795	0.025	2.133e-43	-3.4391444	-3.5404594
Infliximab	Microangiopathy	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	7	174	22495	2983479	1.69	0.896	2.963	2.167	4.154	2.167	0.042	1.75344579	0.52472853
Infliximab	Micrococcus infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	10	22501	2983643	1.126	0.26	3.522	4.368	2.43	4.368	0.119	0.87500312	0.11867153
Infliximab	Microcytic anaemia	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	6	423	22496	2983230	1.05	0.53	1.911	1.185	0.169	1.185	0.681	0.72208044	0.04879016
Infliximab	Microlithiasis	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	29	22501	2983624	0.914	0.212	2.855	1.843	0.373	1.844	0.541	0.69688322	-0.0899247
Infliximab	Microsporidia infection	Protozoal infections NEC	Protozoal infectious disorders	Infec	1968-2006	2	4	22500	2983649	2.07	0.66	5.34	25.692	27.198	25.715	1.837e-7	1.51073838	0.72754861
Infliximab	Micturition disorder	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	5	359	22497	2983294	0.821	0.39	1.569	0.893	0.063	0.893	0.802	0.67684369	-0.1972322
Infliximab	Micturition urgency	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	7	1708	22495	2981945	0.543	0.288	0.951	0.545	2.617	0.545	0.106	-0.8021558	-0.610646
Infliximab	Middle insomnia	Disturbances in initiating and maintaining sleep	Sleep disorders and disturbances	Psych	1968-2006	4	1463	22498	2982190	0.208	0.091	0.423	0.19	13.602	0.19	0.000226	-1.2722882	-1.5702172
Infliximab	Migraine	Migraine headaches	Headaches	Nerv	1968-2006	43	9777	22459	2973876	0.475	0.368	0.605	0.469	25.658	0.468	4.075e-7	-0.7754218	-0.7444405
Infliximab	Migraine without aura	Migraine headaches	Headaches	Nerv	1968-2006	1	45	22501	2983608	0.84	0.194	2.621	1.436	0.132	1.436	0.716	0.56225713	-0.1743534
Infliximab	Milk allergy	Allergies to foods, food additives, drugs and other chemicals	Allergic conditions	Immun	1968-2006	1	19	22501	2983634	0.986	0.228	3.079	2.397	0.767	2.397	0.381	0.78788532	-0.0140989
Infliximab	Miller Fisher syndrome	Acute polyneuropathies	Peripheral neuropathies	Nerv	1968-2006	1	10	22501	2983643	1.204	0.278	3.773	6.793	4.62	6.794	0.032	0.87500312	0.18564935
Infliximab	Miosis	Pupil disorders	Ocular neuromuscular disorders	Eye	1968-2006	1	1639	22501	2982014	0.085	0.019	0.265	0.059	15.104	0.059	0.0001017	-2.7423696	-2.465104
Infliximab	Miscarriage of partner	Family and partner issues	Family issues	SocCi	1968-2006	1	16	22501	2983637	1.099	0.254	3.436	3.878	1.947	3.878	0.163	0.81634411	0.09440068
Infliximab	Mitral valve calcification	Mitral valvular disorders	Cardiac valve disorders	Card	1968-2006	3	139	22499	2983514	1.097	0.426	2.426	1.458	0.41	1.458	0.522	0.94440935	0.09257918
Infliximab	Mitral valve disease	Mitral valvular disorders	Cardiac valve disorders	Card	1968-2006	10	845	22492	2982808	1.31	0.769	2.116	1.466	1.42	1.467	0.233	0.56067041	0.27002714
Infliximab	Mitral valve incompetence	Mitral valvular disorders	Cardiac valve disorders	Card	1968-2006	72	4043	22430	2979610	1.706	1.401	2.061	1.775	23.183	1.778	1.473e-6	1.18598122	0.53415145
Infliximab	Mitral valve prolapse	Mitral valvular disorders	Cardiac valve disorders	Card	1968-2006	3	718	22499	2982935	0.402	0.156	0.889	0.387	2.843	0.387	0.092	-0.6885607	-0.9113032
Infliximab	Mitral valve repair	Cardiac valve therapeutic procedures	Cardiac therapeutic procedures	Surg	1968-2006	2	48	22500	2983605	1.583	0.513	3.978	4.475	4.902	4.475	0.027	1.11543829	0.45932178
Infliximab	Mitral valve stenosis	Mitral valvular disorders	Cardiac valve disorders	Card	1968-2006	4	196	22498	2983457	1.472	0.643	2.992	2.125	2.204	2.125	0.138	0.99076203	0.38662202
Infliximab	Mixed connective tissue disease	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	2	47	22500	2983606	1.336	0.433	3.351	2.744	2.005	2.744	0.157	1.12331827	0.28968008
Infliximab	Mixed salivary tumour	Salivary gland neoplasms unspecified malignancy	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.373	0.313	4.364	1087.839	84.503	1095.499	3.835e-20	0.97840063	0.31699813
Infliximab	Mobility decreased	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	22	1300	22480	2982353	0.86	0.601	1.201	0.876	0.378	0.875	0.539	1.06642295	-0.1508229
Infliximab	Mole excision	Skin lesion excisions	Skin and subcutaneous tissue therapeutic procedures	Surg	1968-2006	1	16	22501	2983637	1.083	0.25	3.385	3.573	1.723	3.573	0.189	0.81634411	0.07973497
Infliximab	Molluscum contagiosum	Molluscum contagiosum viral infections	Viral infectious disorders	Infec	1968-2006	6	29	22496	2983624	4.358	2.081	9.793	15.851	62.044	15.852	3.359e-15	2.4608032	1.47201324
Infliximab	Monarthritis	Arthropathies NEC	Joint disorders	Musc	1968-2006	12	135	22490	2983518	3.777	2.318	5.901	6.074	44.243	6.077	2.9e-11	2.61890939	1.32893004
Infliximab	Monoclonal immunoglobulin present	Immunoglobulin analyses	Immunology and allergy investigations	Inv	1968-2006	2	41	22500	2983612	1.384	0.448	3.472	3.009	2.426	3.01	0.119	1.17152386	0.32497786
Infliximab	Monocyte count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	149	22501	2983504	0.431	0.1	1.345	0.412	0.843	0.412	0.358	-0.0968774	-0.8416472
Infliximab	Monocyte count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	10	333	22492	2983320	1.644	0.965	2.655	1.937	4.323	1.937	0.038	1.61353283	0.4971323
Infliximab	Monocyte percentage decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	60	22500	2983593	1.155	0.374	2.897	1.913	0.844	1.913	0.358	1.0240899	0.14410034
Infliximab	Monocyte percentage increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	93	22499	2983560	1.299	0.505	2.873	1.924	1.279	1.924	0.258	1.20788974	0.26159474
Infliximab	Monocytopenia	Leukopenias NEC	White blood cell disorders	Blood	1968-2006	1	14	22501	2983639	1.173	0.271	3.671	6.05	3.542	6.05	0.06	0.83563334	0.15956457
Infliximab	Monocytosis	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	1	344	22501	2983309	0.515	0.119	1.609	0.541	0.386	0.541	0.534	-0.8519444	-0.6635884
Infliximab	Mononeuritis	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	14	82	22488	2983571	6.489	3.878	11.723	13.015	121.576	13.03	2.858e-28	3.11478258	1.87010844
Infliximab	Mononeuropathy	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	1	30	22501	2983623	1.014	0.234	3.167	2.586	0.974	2.586	0.324	0.68809089	0.01390291
Infliximab	Mononeuropathy multiplex	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	9	35	22493	2983618	6.008	3.076	14.09	16.395	96.25	16.412	1.013e-22	2.90034338	1.79309191
Infliximab	Mononucleosis heterophile test positive	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	26	22501	2983627	1.03	0.238	3.219	2.875	1.121	2.875	0.29	0.72358631	0.0295588
Infliximab	Mononucleosis syndrome	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	1	65	22501	2983588	0.714	0.165	2.228	0.984	0	0.984	0.987	0.40991926	-0.3368723
Infliximab	Monoparesis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	12	415	22490	2983238	2.49	1.531	3.873	3.186	17.049	3.188	0.00003643	1.62030627	0.91228271
Infliximab	Monoplegia	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	7	408	22495	2983245	0.913	0.484	1.6	0.985	0.002	0.985	0.968	0.95108789	-0.0910194
Infliximab	Mood altered	Emotional and mood disturbances NEC	Mood disorders and disturbances NEC	Psych	1968-2006	4	1684	22498	2981969	0.148	0.065	0.301	0.134	22.372	0.134	2.246e-6	-1.4589891	-1.910543
Infliximab	Mood swings	Fluctuating mood symptoms	Mood disorders and disturbances NEC	Psych	1968-2006	4	3544	22498	2980109	0.082	0.036	0.167	0.073	47.333	0.073	5.99e-12	-2.4750178	-2.501036
Infliximab	Moraxella infection	Moraxella infections	Bacterial infectious disorders	Infec	1968-2006	3	33	22499	2983620	2.013	0.781	4.464	5.136	8.95	5.137	0.003	1.64491562	0.69962615
Infliximab	Morganella infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	27	22500	2983626	1.587	0.514	3.989	4.562	4.993	4.563	0.025	1.29069204	0.46184544
Infliximab	Morphoea	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	2	56	22500	2983597	1.314	0.426	3.297	2.602	1.829	2.602	0.176	1.05390137	0.27307592
Infliximab	Mortons neuroma	Neuromas	Nervous system neoplasms benign	Neopl	1968-2006	1	15	22501	2983638	1.138	0.263	3.561	4.546	2.663	4.546	0.103	0.82595649	0.12927234
Infliximab	Motion sickness	Inner ear signs and symptoms	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	1	202	22501	2983451	0.335	0.077	1.048	0.286	1.741	0.286	0.187	-0.3440845	-1.0936247
Infliximab	Motor dysfunction	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	11	950	22491	2982703	0.745	0.448	1.179	0.764	0.788	0.764	0.375	0.53920488	-0.2943711
Infliximab	Mountain sickness acute	Atmospheric pressure injuries	Injuries by physical agents	Inj&P	1968-2006	1	15	22501	2983638	1.076	0.249	3.362	3.602	1.63	3.602	0.202	0.82595649	0.07325046
Infliximab	Mouth cyst	Benign oral cavity neoplasms	Benign neoplasms gastrointestinal	Gastr	1968-2006	2	21	22500	2983632	1.612	0.522	4.053	4.997	5.452	4.998	0.02	1.34493959	0.47747564
Infliximab	Mouth haemorrhage	Oral soft tissue haemorrhages	Oral soft tissue conditions	Gastr	1968-2006	7	955	22495	2982698	0.52	0.276	0.911	0.518	3.069	0.518	0.08	-0.0470772	-0.6539265
Infliximab	Mouth injury	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	3	108	22499	2983545	1.129	0.439	2.496	1.517	0.519	1.517	0.471	1.11657892	0.12133229
Infliximab	Mouth ulceration	Stomatitis and ulceration	Oral soft tissue conditions	Gastr	1968-2006	55	5970	22447	2977683	1.35	1.077	1.674	1.387	5.763	1.388	0.016	0.26696335	0.30010459
Infliximab	Movement disorder	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	44	3779	22458	2979874	0.995	0.773	1.265	1.009	0.004	1.009	0.951	0.59086437	-0.0050125
Infliximab	Mucormycosis	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	4	56	22498	2983597	2.069	0.903	4.21	4.066	8.194	4.067	0.004	1.77588455	0.7270654
Infliximab	Mucosal dryness	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	1	246	22501	2983407	0.331	0.077	1.035	0.285	1.792	0.285	0.181	-0.5213485	-1.1056369
Infliximab	Mucosal erosion	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	2	407	22500	2983246	0.501	0.162	1.255	0.509	0.943	0.509	0.331	-0.4480828	-0.6911492
Infliximab	Mucosal haemorrhage	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	5	186	22497	2983467	1.521	0.721	2.906	2.028	2.528	2.028	0.112	1.29325792	0.41936801
Infliximab	Mucosal inflammation	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	15	2795	22487	2980858	0.368	0.238	0.549	0.361	16.881	0.36	0.00003979	-0.4738318	-0.9996723
Infliximab	Mucosal ulceration	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	4	226	22498	2983427	1.25	0.546	2.54	1.618	0.93	1.619	0.335	0.86651296	0.22314355
Infliximab	Mucous membrane disorder	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	5	1778	22497	2981875	0.525	0.249	1.002	0.529	2.084	0.528	0.149	-1.2693434	-0.644357
Infliximab	Mucous stools	Faecal abnormalities NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	47	22501	2983606	0.769	0.178	2.399	1.163	0.022	1.163	0.883	0.54627889	-0.2626643
Infliximab	Multi-organ disorder	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	4	455	22498	2983198	0.507	0.221	1.03	0.509	1.873	0.509	0.171	0.16168869	-0.6792443
Infliximab	Multi-organ failure	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	161	5837	22341	2977816	1.836	1.61	2.086	1.889	65.092	1.898	7.15e-16	1.8058606	0.60758929
Infliximab	Multifocal micronodular pneumocyte hyperplasia	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	1	0	22501	2983653	1.399	0.317	4.473	1096.538	154.561	1104.269	1.746e-35	0.97840063	0.3357577
Infliximab	Multigravida	Pregnancy related circumstances	Gender related factors	SocCi	1968-2006	1	1	22501	2983652	1.332	0.305	4.207	101.504	20.439	101.504	6.156e-6	0.967721	0.28668157
Infliximab	Multiple allergies	Allergic conditions NEC	Allergic conditions	Immun	1968-2006	3	264	22499	2983389	0.6	0.233	1.327	0.626	0.646	0.626	0.422	0.40475473	-0.5108256
Infliximab	Multiple drug overdose	Overdoses	Medication errors	Inj&P	1968-2006	3	3896	22499	2979757	0.057	0.022	0.126	0.049	56.925	0.049	4.528e-14	-2.9284938	-2.864704
Infliximab	Multiple fractures	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	2	217	22500	2983436	0.532	0.172	1.334	0.551	0.728	0.551	0.393	0.17387238	-0.6311118
Infliximab	Multiple myeloma	Multiple myelomas	Plasma cell neoplasms	Neopl	1968-2006	28	1453	22474	2982200	1.027	0.747	1.383	1.052	0.071	1.053	0.789	1.25120452	0.02664193
Infliximab	Multiple sclerosis	Multiple sclerosis acute and progressive	Demyelinating disorders	Nerv	1968-2006	49	4823	22453	2978830	0.67	0.528	0.842	0.669	7.971	0.668	0.005	0.40307985	-0.4004776
Infliximab	Multiple-drug resistance	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	1	60	22501	2983593	0.631	0.146	1.971	0.766	0.068	0.766	0.794	0.44652257	-0.4604494
Infliximab	Mumps	Mumps viral infections	Viral infectious disorders	Infec	1968-2006	1	33	22501	2983620	0.857	0.198	2.674	1.515	0.176	1.515	0.675	0.66203088	-0.1543174
Infliximab	Muscle abscess	Muscle and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	6	39	22496	2983614	3.43	1.717	6.363	8.629	33.999	8.63	5.513e-9	2.37766865	1.23256026
Infliximab	Muscle atrophy	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	15	1929	22487	2981724	0.667	0.432	0.994	0.674	2.341	0.673	0.126	0.0292518	-0.4049652
Infliximab	Muscle contractions involuntary	Neuromuscular disorders NEC	Neuromuscular disorders	Nerv	1968-2006	6	763	22496	2982890	0.634	0.32	1.154	0.653	1.103	0.653	0.294	0.0399344	-0.4557063
Infliximab	Muscle contracture	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	149	22501	2983504	0.399	0.092	1.244	0.366	1.089	0.366	0.297	-0.0968774	-0.9187939
Infliximab	Muscle disorder	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	13	1709	22489	2981944	0.515	0.323	0.788	0.513	5.977	0.512	0.014	-0.0002543	-0.6635884
Infliximab	Muscle fatigue	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	1	198	22501	2983455	0.305	0.07	0.952	0.254	2.168	0.254	0.141	-0.3268353	-1.1874435
Infliximab	Muscle haemorrhage	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	2	542	22500	2983111	0.357	0.116	0.896	0.333	2.641	0.333	0.104	-0.7686954	-1.0300195
Infliximab	Muscle injury	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	4	1127	22498	2982526	0.247	0.108	0.502	0.23	10.303	0.23	0.001	-0.9321929	-1.3983669
Infliximab	Muscle necrosis	Myopathies	Muscle disorders	Musc	1968-2006	1	320	22501	2983333	0.282	0.065	0.879	0.229	2.558	0.229	0.11	-0.7777093	-1.2658482
Infliximab	Muscle rigidity	Muscle tone abnormalities	Muscle disorders	Musc	1968-2006	7	2531	22495	2981122	0.263	0.14	0.461	0.253	15.515	0.253	0.00008185	-1.3338261	-1.3356012
Infliximab	Muscle rupture	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	3	194	22499	2983459	0.856	0.332	1.892	1.005	0	1.005	0.993	0.68186784	-0.1554849
Infliximab	Muscle spasms	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	133	17729	22369	2965924	0.554	0.48	0.637	0.549	49.383	0.546	2.106e-12	-0.0269814	-0.5905906
Infliximab	Muscle spasticity	Neuromuscular disorders NEC	Neuromuscular disorders	Nerv	1968-2006	2	498	22500	2983155	0.26	0.084	0.652	0.23	5.123	0.23	0.024	-0.6718119	-1.3470736
Infliximab	Muscle strain	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	3	371	22499	2983282	0.496	0.193	1.095	0.497	1.502	0.497	0.22	0.06316979	-0.7011794
Infliximab	Muscle tightness	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	4	886	22498	2982767	0.253	0.11	0.513	0.234	9.913	0.234	0.002	-0.627046	-1.3743658
Infliximab	Muscle twitching	Muscle related signs and symptoms NEC	Muscle disorders	Musc	1968-2006	14	7472	22488	2976181	0.305	0.195	0.461	0.297	23.2	0.296	0.00000146	-1.9413415	-1.1874435
Infliximab	Muscular dystrophy	Non-site specific muscle disorders congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	1	68	22501	2983585	0.71	0.164	2.217	0.973	0.001	0.973	0.978	0.38839484	-0.3424903
Infliximab	Muscular weakness	Muscle weakness conditions	Muscle disorders	Musc	1968-2006	76	7307	22426	2976346	0.728	0.601	0.875	0.726	7.749	0.725	0.005	0.43826896	-0.3174542
Infliximab	Musculoskeletal chest pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	21	1112	22481	2982541	1.067	0.739	1.501	1.107	0.209	1.107	0.648	1.20303714	0.06485097
Infliximab	Musculoskeletal discomfort	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	11	474	22491	2983179	1.16	0.698	1.836	1.257	0.562	1.257	0.453	1.3627645	0.14842001
Infliximab	Musculoskeletal disorder	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	6	423	22496	2983230	0.955	0.482	1.739	1.055	0.016	1.055	0.898	0.72208044	-0.0460439
Infliximab	Musculoskeletal pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	11	954	22491	2982699	0.72	0.434	1.14	0.737	1.025	0.737	0.311	0.53394049	-0.3285041
Infliximab	Musculoskeletal stiffness	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	58	4932	22444	2978721	0.927	0.744	1.144	0.934	0.261	0.934	0.609	0.60819895	-0.0758017
Infliximab	Myalgia	Muscle pains	Muscle disorders	Musc	1968-2006	325	43492	22177	2940161	0.961	0.877	1.052	0.962	0.486	0.961	0.486	-0.0451678	-0.0397809
Infliximab	Myasthenia gravis	Neuromuscular junction dysfunction	Neuromuscular disorders	Nerv	1968-2006	4	477	22498	2983176	0.556	0.243	1.13	0.568	1.303	0.567	0.254	0.10908851	-0.586987
Infliximab	Mycetoma mycotic	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	12	22501	2983641	1.114	0.257	3.483	4.144	2.198	4.144	0.138	0.85518395	0.10795714
Infliximab	Mycobacteria blood test positive	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	9	22501	2983644	1.197	0.277	3.751	6.744	4.381	6.744	0.036	0.88501574	0.17981843
Infliximab	Mycobacteria sputum test positive	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	14	22500	2983639	1.942	0.625	4.938	14.026	16.761	14.026	0.0000424	1.41091905	0.66371837
Infliximab	Mycobacteria tissue specimen test positive	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	3	6	22499	2983647	3.243	1.135	13.138	37.618	67.433	37.636	2.18e-16	1.89509839	1.17649883
Infliximab	Mycobacteria urine test positive	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	20	22501	2983633	1.152	0.266	3.605	5.162	2.981	5.162	0.084	0.77852244	0.14149956
Infliximab	Mycobacterial infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	37	153	22465	2983500	11.649	8.191	15.759	16.637	404.291	16.671	0	3.96068401	2.45522034
Infliximab	Mycobacterium avium complex infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	67	269	22435	2983384	12.21	9.719	15.045	16.897	732.398	16.948	0	4.26293396	2.50225529
Infliximab	Mycobacterium chelonei infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	10	17	22492	2983636	10.613	4.319	23.29	29.053	152.641	29.06	4.589e-35	3.18301868	2.36207966
Infliximab	Mycobacterium fortuitum infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	4	15	22498	2983638	2.961	1.277	6.181	11.269	29.702	11.272	5.038e-8	2.11923763	1.08552705
Infliximab	Mycobacterium kansasii infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	8	17	22494	2983636	10.015	3.617	25.951	30.657	136.763	30.66	1.359e-31	2.91159249	2.30408397
Infliximab	Mycobacterium marinum infection	Atypical mycobacterial infections	Mycobacterial infectious disorders	Infec	1968-2006	7	8	22495	2983645	10.904	3.405	30.373	45.802	140.947	45.82	1.653e-32	2.83563365	2.38912969
Infliximab	Mycoplasma infection	Mycoplasma infections	Mycoplasmal infectious disorders	Infec	1968-2006	6	97	22496	2983556	2.506	1.264	4.571	4.197	13.95	4.198	0.0001878	1.97191361	0.91868786
Infliximab	Mycosis fungoides	Mycoses fungoides	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	22	161	22480	2983492	7.117	4.752	10.998	11.902	173.061	11.916	1.587e-39	3.26786828	1.96248629
Infliximab	Mycotic aneurysm	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	13	22501	2983640	1.131	0.261	3.537	4.844	2.512	4.844	0.113	0.84537553	0.1231022
Infliximab	Mydriasis	Pupil disorders	Ocular neuromuscular disorders	Eye	1968-2006	8	4845	22494	2978808	0.226	0.125	0.384	0.215	22.783	0.214	1.814e-6	-2.0653749	-1.4872203
Infliximab	Myelitis	Myelitis (incl infective)	Central nervous system infections and inflammations	Nerv	1968-2006	10	410	22492	2983243	2.926	1.717	4.732	4.258	23.26	4.26	1.415e-6	1.39742876	1.0736363
Infliximab	Myelitis transverse	Myelitis (incl infective)	Central nervous system infections and inflammations	Nerv	1968-2006	5	117	22497	2983536	1.784	0.846	3.41	2.632	4.739	2.632	0.029	1.63807195	0.57885803
Infliximab	Myelocytosis	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	2	13	22500	2983640	1.683	0.545	4.235	6.155	6.909	6.156	0.009	1.4205959	0.52057792
Infliximab	Myelodysplastic syndrome	Myelodysplastic syndromes	Leukaemias	Neopl	1968-2006	21	1325	22481	2982328	1.017	0.705	1.431	1.05	0.049	1.05	0.824	0.97868725	0.01685712
Infliximab	Myelodysplastic syndrome unclassifiable	Myelodysplastic syndromes	Leukaemias	Neopl	1968-2006	1	0	22501	2983653	1.344	0.308	4.254	1075.473	51.196	1083.041	8.358e-13	0.97840063	0.29565024
Infliximab	Myelofibrosis	Myeloproliferative disorders (excl leukaemias)	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	2	265	22500	2983388	0.626	0.203	1.569	0.685	0.284	0.685	0.594	-0.0102831	-0.4684049
Infliximab	Myeloid leukaemia	Leukaemias myeloid NEC	Leukaemias	Neopl	1968-2006	9	104	22493	2983549	3.854	2.188	6.448	7.152	43.115	7.153	5.162e-11	2.42675877	1.34911157
Infliximab	Myeloid maturation arrest	Marrow depression and hypoplastic anaemias	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	1	100	22501	2983553	0.924	0.214	2.884	1.878	0.412	1.878	0.521	0.1768059	-0.0790432
Infliximab	Myeloid metaplasia	Myeloproliferative disorders (excl leukaemias)	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	4	308	22498	2983345	1.318	0.575	2.678	1.772	1.271	1.772	0.26	0.57307289	0.27611544
Infliximab	Myelopathy	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	6	199	22496	2983454	1.653	0.834	3.011	2.186	3.644	2.186	0.056	1.45472405	0.50259182
Infliximab	Myeloproliferative disorder	Myeloproliferative disorders (excl leukaemias)	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	1	234	22501	2983419	0.623	0.144	1.945	0.749	0.082	0.749	0.775	-0.4751226	-0.4732088
Infliximab	Myocardial infarction	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	372	43713	22130	2939940	0.629	0.577	0.684	0.624	86.731	0.617	1.243e-20	0.14025685	-0.463624
Infliximab	Myocardial ischaemia	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	62	3564	22440	2980089	1.529	1.236	1.874	1.582	12.736	1.584	0.0003586	1.15007708	0.42461393
Infliximab	Myocardial rupture	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	1	93	22501	2983560	0.578	0.134	1.804	0.652	0.179	0.652	0.673	0.22051265	-0.5481814
Infliximab	Myocarditis	Noninfectious myocarditis	Myocardial disorders	Card	1968-2006	16	1188	22486	2982465	1.353	0.888	1.992	1.458	2.229	1.458	0.135	0.75234584	0.30232435
Infliximab	Myocarditis septic	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	6	22501	2983647	1.279	0.295	4.022	16.534	9.819	16.534	0.002	0.91547736	0.24607852
Infliximab	Myoclonic epilepsy	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	1	2023	22501	2981630	0.201	0.046	0.628	0.151	4.699	0.151	0.03	-3.0253029	-1.6044504
Infliximab	Myoclonus	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	4	1995	22498	2981658	0.2	0.087	0.405	0.183	14.473	0.183	0.0001422	-1.6865473	-1.6094379
Infliximab	Myofascial pain syndrome	Muscle pains	Muscle disorders	Musc	1968-2006	1	81	22501	2983572	0.686	0.159	2.142	0.906	0.01	0.906	0.922	0.29866351	-0.3768777
Infliximab	Myopathy	Myopathies	Muscle disorders	Musc	1968-2006	18	4374	22484	2979279	0.549	0.369	0.792	0.547	6.696	0.547	0.01	-0.8471969	-0.5996568
Infliximab	Myopathy steroid	Myopathies	Muscle disorders	Musc	1968-2006	5	101	22497	2983552	1.937	0.918	3.702	3.028	6.309	3.028	0.012	1.73134135	0.66114038
Infliximab	Myopathy toxic	Myopathies	Muscle disorders	Musc	1968-2006	3	61	22499	2983592	1.686	0.655	3.732	3.283	4.325	3.284	0.038	1.42444967	0.52235886
Infliximab	Myopia	Refractive and accommodative disorders	Vision disorders	Eye	1968-2006	1	318	22501	2983335	0.249	0.057	0.776	0.198	3.257	0.198	0.071	-0.7713472	-1.3903024
Infliximab	Myositis	Muscle infections and inflammations	Muscle disorders	Musc	1968-2006	39	2919	22463	2980734	1.496	1.143	1.929	1.562	7.601	1.563	0.006	0.77726362	0.40279488
Infliximab	Naegleria infection	Amoebic infections	Protozoal infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.381	0.314	4.398	1090.869	100.398	1098.551	1.247e-23	0.97840063	0.32280787
Infliximab	Nail discolouration	Nail and nail bed conditions (excl infections and infestations)	Skin appendage conditions	Skin	1968-2006	2	288	22500	2983365	0.47	0.152	1.178	0.465	1.2	0.465	0.273	-0.0908353	-0.7550226
Infliximab	Nail disorder	Nail and nail bed conditions (excl infections and infestations)	Skin appendage conditions	Skin	1968-2006	2	3188	22500	2980465	0.181	0.059	0.454	0.154	9.244	0.154	0.002	-3.0642247	-1.7092582
Infliximab	Nail infection	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	2	71	22500	2983582	1.043	0.338	2.615	1.566	0.391	1.566	0.532	0.94514885	0.04210118
Infliximab	Nail psoriasis	Psoriatic conditions	Epidermal and dermal conditions	Skin	1968-2006	1	6	22501	2983647	1.219	0.281	3.82	7.415	5.29	7.415	0.021	0.91547736	0.19803085
Infliximab	Nasal abscess	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	2	8	22500	2983645	1.918	0.618	4.869	11.195	15.43	11.195	0.00008562	1.46997828	0.65128298
Infliximab	Nasal cavity cancer	Paranasal sinus and nasal cavity neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	15	22501	2983638	1.12	0.259	3.502	4.142	2.315	4.142	0.128	0.82595649	0.11332869
Infliximab	Nasal congestion	Nasal congestion and inflammations	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	20	2327	22482	2981326	0.586	0.402	0.83	0.585	5.833	0.584	0.016	0.16560485	-0.5344355
Infliximab	Nasal cyst	Upper respiratory tract neoplasms	Respiratory tract neoplasms	Resp	1968-2006	3	9	22499	2983644	2.771	1.045	6.535	21.998	38.242	22.004	6.25e-10	1.86505959	1.01920827
Infliximab	Nasal discomfort	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	1	714	22501	2982939	0.135	0.031	0.423	0.097	8.361	0.097	0.004	-1.6783939	-2.0024805
Infliximab	Nasal neoplasm	Paranasal sinus and nasal cavity neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	6	22501	2983647	1.239	0.286	3.889	10.297	6.431	10.297	0.011	0.91547736	0.2143046
Infliximab	Nasal oedema	Nasal disorders NEC	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	167	22501	2983486	0.426	0.099	1.331	0.4	0.874	0.4	0.35	-0.1856664	-0.8533159
Infliximab	Nasal operation	Nasal therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	2	22	22500	2983631	1.79	0.578	4.516	7.901	9.834	7.902	0.002	1.33575551	0.58221562
Infliximab	Nasal polyps	Nasal disorders NEC	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	3	105	22499	2983548	1.355	0.526	2.995	2.073	1.596	2.074	0.206	1.13438467	0.30380145
Infliximab	Nasal septum deviation	Nasal disorders NEC	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	2	87	22500	2983566	0.99	0.321	2.483	1.418	0.238	1.418	0.626	0.8375254	-0.0100503
Infliximab	Nasal septum perforation	Nasal disorders NEC	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	106	22501	2983547	0.564	0.13	1.759	0.63	0.219	0.63	0.64	0.14036864	-0.572701
Infliximab	Nasal sinus cancer	Paranasal sinus and nasal cavity neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	12	22500	2983641	1.902	0.613	4.823	10.752	14.494	10.754	0.0001406	1.43033808	0.64290596
Infliximab	Nasal ulcer	Nasal disorders NEC	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	6	94	22496	2983559	2.573	1.297	4.695	4.595	15.057	4.595	0.0001043	1.99032522	0.94507253
Infliximab	Nasopharyngeal cancer	Oropharyngeal, nasopharyngeal and tonsillar neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	4	19	22498	2983634	3.091	1.325	6.547	14.309	34.624	14.309	3.999e-9	2.08190533	1.12849466
Infliximab	Nasopharyngeal disorder	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	4	414	22498	2983239	0.648	0.283	1.316	0.68	0.592	0.68	0.442	0.26514553	-0.4338646
Infliximab	Nasopharyngitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	76	4010	22426	2979643	1.107	0.914	1.331	1.121	0.969	1.122	0.325	1.2728404	0.10165365
Infliximab	Natural killer-cell leukaemia	Leukaemias chronic T-cell	Leukaemias	Neopl	1968-2006	1	3	22501	2983650	1.316	0.302	4.152	21.58	15.849	21.58	0.00006862	0.946596	0.27459683
Infliximab	Nausea	Nausea and vomiting symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	776	113970	21726	2869683	0.72	0.679	0.764	0.716	90.983	0.705	1.449e-21	-0.2132968	-0.3285041
Infliximab	Neck mass	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	5	144	22497	2983509	1.385	0.657	2.645	1.785	1.631	1.785	0.202	1.49318279	0.32570014
Infliximab	Neck pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	56	5698	22446	2977955	0.862	0.689	1.067	0.866	1.131	0.866	0.288	0.357553	-0.1485
Infliximab	Necrosis	Necrosis NEC	Tissue disorders NEC	Genrl	1968-2006	53	2321	22449	2981332	1.912	1.519	2.381	2.018	26.052	2.021	3.324e-7	1.51255884	0.64814981
Infliximab	Necrosis ischaemic	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	6	137	22496	2983516	2.109	1.064	3.842	3.258	8.376	3.259	0.004	1.74653918	0.7462139
Infliximab	Necrotising fasciitis	Muscle and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	13	280	22489	2983373	2.405	1.507	3.682	2.998	16.372	3	0.00005206	2.12137784	0.8775499
Infliximab	Necrotising fasciitis staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.351	0.309	4.282	102.876	28.96	102.876	7.389e-8	0.967721	0.30084506
Infliximab	Necrotising fasciitis streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	3	12	22499	2983641	2.468	0.95	5.558	12.327	22.129	12.328	0.00000255	1.83563345	0.90340811
Infliximab	Necrotising granulomatous lymphadenitis	Lymphatic system disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	4	14	22498	2983639	2.92	1.261	6.074	11.789	28.164	11.793	1.115e-7	2.12872362	1.07158362
Infliximab	Needle biopsy site unspecified abnormal	Histopathology procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	1	4	22501	2983649	1.292	0.298	4.067	20.56	11.526	20.56	0.001	0.93614837	0.25619141
Infliximab	Neonatal disorder	Newborn complications NEC	Neonatal and perinatal conditions	Preg	1968-2006	8	2949	22494	2980704	0.196	0.108	0.332	0.186	28.603	0.185	8.885e-8	-1.3742866	-1.6296406
Infliximab	Neonatal infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	76	22501	2983577	0.658	0.152	2.052	0.833	0.033	0.833	0.855	0.33251843	-0.4185503
Infliximab	Neonatal pneumonia	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	1	26	22501	2983627	0.908	0.21	2.835	1.801	0.347	1.801	0.556	0.72358631	-0.0965109
Infliximab	Neonatal respiratory arrest	Neonatal hypoxic conditions	Neonatal respiratory disorders	Resp	1968-2006	1	62	22501	2983591	0.73	0.169	2.279	1.033	0.001	1.033	0.974	0.43176963	-0.3147107
Infliximab	Neonatal respiratory distress syndrome	Neonatal hypoxic conditions	Neonatal respiratory disorders	Resp	1968-2006	5	760	22497	2982893	0.426	0.202	0.814	0.42	4.007	0.42	0.045	-0.1760488	-0.8533159
Infliximab	Neonatal tachycardia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	1	47	22501	2983606	0.749	0.173	2.338	1.093	0.008	1.093	0.93	0.54627889	-0.2890163
Infliximab	Neoplasm	Neoplasms unspecified malignancy and site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	46	2444	22456	2981209	3.213	2.51	4.064	3.664	81.56	3.671	1.7e-19	1.24696023	1.16720508
Infliximab	Neoplasm malignant	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	97	4654	22405	2978999	2.524	2.131	2.972	2.702	96.891	2.71	7.323e-23	1.40931733	0.92584494
Infliximab	Neoplasm of appendix	Gastrointestinal neoplasms malignancy unspecified NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	4	22501	2983649	1.263	0.291	3.966	13.795	8.222	13.795	0.004	0.93614837	0.23348984
Infliximab	Neoplasm progression	Neoplasms unspecified malignancy and site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	4	540	22498	2983113	0.395	0.172	0.802	0.384	3.945	0.384	0.047	-0.0317291	-0.9288695
Infliximab	Neoplasm prostate	Reproductive neoplasms male unspecified malignancy	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	2	93	22500	2983560	1.474	0.478	3.702	3.484	3.366	3.485	0.067	0.79914989	0.38797979
Infliximab	Neoplasm recurrence	Neoplasms unspecified malignancy and site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	9	527	22493	2983126	0.856	0.489	1.415	0.9	0.1	0.9	0.752	0.9854112	-0.1554849
Infliximab	Neoplasm skin	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	6	361	22496	2983292	2.208	1.114	4.024	3.392	9.645	3.392	0.002	0.89056313	0.79208713
Infliximab	Nephrectomy	Renal therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	3	164	22499	2983489	0.995	0.387	2.201	1.255	0.147	1.255	0.701	0.8191261	-0.0050125
Infliximab	Nephritis	Nephritis NEC	Nephropathies	Renal	1968-2006	7	2448	22495	2981205	0.967	0.513	1.695	1.055	0.02	1.055	0.888	-1.2882538	-0.0335568
Infliximab	Nephritis autoimmune	Nephritis NEC	Nephropathies	Renal	1968-2006	1	2	22501	2983651	1.348	0.309	4.268	67.596	26.833	67.596	2.218e-7	0.95711984	0.29862201
Infliximab	Nephritis interstitial	Nephritis NEC	Nephropathies	Renal	1968-2006	7	1952	22495	2981701	0.276	0.146	0.484	0.264	14.243	0.263	0.0001606	-0.9811378	-1.2873544
Infliximab	Nephroblastoma	Non-renal cell kidney neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	23	22501	2983630	0.985	0.228	3.078	2.339	0.761	2.339	0.383	0.75079293	-0.0151136
Infliximab	Nephrocalcinosis	Renal lithiasis	Urolithiases	Renal	1968-2006	2	112	22500	2983541	1.062	0.344	2.663	1.623	0.456	1.623	0.5	0.6839525	0.06015392
Infliximab	Nephrolithiasis	Renal lithiasis	Urolithiases	Renal	1968-2006	74	3977	22428	2979676	1.823	1.501	2.197	1.907	30.239	1.91	3.82e-8	1.24690508	0.6004835
Infliximab	Nephropathy	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	2	541	22500	2983112	0.303	0.098	0.76	0.273	3.798	0.273	0.051	-0.7665643	-1.1940225
Infliximab	Nephrosclerosis	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	4	391	22498	2983262	0.801	0.35	1.628	0.884	0.059	0.884	0.809	0.32660321	-0.2218943
Infliximab	Nephrotic syndrome	Glomerulonephritis and nephrotic syndrome	Nephropathies	Renal	1968-2006	29	2168	22473	2981485	1.524	1.116	2.043	1.611	6.498	1.612	0.011	0.77024256	0.42133846
Infliximab	Nerve compression	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	4	471	22498	2983182	0.531	0.232	1.079	0.54	1.571	0.54	0.21	0.12324495	-0.6329933
Infliximab	Nerve conduction studies abnormal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	118	22501	2983535	0.648	0.15	2.022	0.81	0.044	0.81	0.833	0.07014349	-0.4338646
Infliximab	Nerve conduction studies normal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	0	22501	2983653	1.373	0.313	4.364	1087.839	84.503	1095.499	3.835e-20	0.97840063	0.31699813
Infliximab	Nerve injury	Nerve injuries NEC	Injuries NEC	Inj&P	1968-2006	4	684	22498	2982969	0.321	0.14	0.652	0.304	6.313	0.304	0.012	-0.3098028	-1.1363142
Infliximab	Nerve root lesion	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	2	108	22500	2983545	0.962	0.312	2.412	1.342	0.171	1.342	0.679	0.70745207	-0.0387408
Infliximab	Nervous system disorder	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	61	7146	22441	2976507	0.599	0.484	0.736	0.596	16.667	0.595	0.00004454	0.15993914	-0.5124937
Infliximab	Nervous system neoplasm benign	Nervous system neoplasms benign NEC	Nervous system neoplasms benign	Neopl	1968-2006	1	2	22501	2983651	1.311	0.301	4.132	30.458	14.785	30.458	0.0001205	0.95711984	0.2707902
Infliximab	Nervousness	Anxiety symptoms	Anxiety disorders and symptoms	Psych	1968-2006	25	24643	22477	2959010	0.218	0.156	0.299	0.212	73.114	0.211	1.224e-17	-2.8587867	-1.5232602
Infliximab	Neuralgia	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	9	1703	22493	2981950	0.546	0.311	0.902	0.548	3.342	0.548	0.068	-0.4778822	-0.6051363
Infliximab	Neurilemmoma benign	Nervous system neoplasms benign NEC	Nervous system neoplasms benign	Neopl	1968-2006	1	4	22501	2983649	1.283	0.295	4.033	17.374	10.2	17.374	0.001	0.93614837	0.24920109
Infliximab	Neuritis	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	14	619	22488	2983034	3.407	2.17	5.15	4.772	38.102	4.774	6.715e-10	1.37515311	1.22583214
Infliximab	Neuroblastoma	Nervous system neoplasms malignant NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	60	22501	2983593	0.723	0.167	2.257	1.011	0	1.011	0.991	0.44652257	-0.3243461
Infliximab	Neurodermatitis	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	1	92	22501	2983561	0.628	0.145	1.96	0.764	0.073	0.764	0.787	0.22686596	-0.4652151
Infliximab	Neuroendocrine carcinoma	Endocrine neoplasms malignant and unspecified NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	5	20	22497	2983633	3.454	1.609	6.888	12.32	39.175	12.323	3.875e-10	2.32662975	1.23953298
Infliximab	Neuroendocrine carcinoma of the skin	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	6	26	22496	2983627	4.319	2.069	9.514	16.583	60.96	16.591	5.825e-15	2.48670722	1.46302389
Infliximab	Neuroendocrine tumour	Endocrine neoplasms malignant and unspecified NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	6	11	22496	2983642	5.345	2.309	17.378	25.928	84.758	25.931	3.372e-20	2.62369932	1.67616154
Infliximab	Neurofibromatosis	Neurological disorders congenital NEC	Neurological disorders congenital	Cong	1968-2006	2	25	22500	2983628	1.562	0.506	3.925	4.332	4.596	4.332	0.032	1.30854889	0.44596705
Infliximab	Neurogenic bladder	Myoneurogenic bladder disorders	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	5	268	22497	2983385	1.081	0.513	2.066	1.268	0.269	1.268	0.604	0.96826694	0.07788654
Infliximab	Neurological examination abnormal	Physical examination procedures	Physical examination topics	Inv	1968-2006	1	128	22501	2983525	0.501	0.116	1.564	0.515	0.449	0.515	0.503	0.01412534	-0.6911492
Infliximab	Neurological infection	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	5	22500	2983648	1.965	0.631	5.006	14.176	18.356	14.176	0.00001832	1.50043989	0.67549225
Infliximab	Neurological symptom	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	14	723	22488	2982930	1.338	0.853	2.019	1.459	1.922	1.459	0.166	1.19156585	0.29117596
Infliximab	Neuroma	Neuromas	Nervous system neoplasms benign	Neopl	1968-2006	1	57	22501	2983596	0.789	0.182	2.462	1.23	0.043	1.23	0.836	0.46893872	-0.236989
Infliximab	Neuromyopathy	Neuromuscular disorders NEC	Neuromuscular disorders	Nerv	1968-2006	2	184	22500	2983469	0.639	0.207	1.603	0.707	0.24	0.707	0.624	0.3156554	-0.4478508
Infliximab	Neuropathy	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	30	1518	22472	2982135	1.047	0.77	1.397	1.073	0.144	1.073	0.704	1.28873041	0.04592893
Infliximab	Neuropathy peripheral	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	91	12643	22411	2971010	1.378	1.157	1.632	1.407	10.407	1.409	0.001	-0.0831355	0.32063317
Infliximab	Neurotoxicity	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	3	2113	22499	2981540	0.17	0.066	0.376	0.151	14.268	0.151	0.0001586	-2.0855877	-1.7719568
Infliximab	Neurotransmitter level altered	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	196	22501	2983457	1.105	0.256	3.456	3.794	2.029	3.795	0.154	-0.3181327	0.09984533
Infliximab	Neutropenia	Neutropenias	White blood cell disorders	Blood	1968-2006	96	14166	22406	2969487	0.494	0.417	0.582	0.489	51.306	0.487	7.904e-13	-0.1694093	-0.7052198
Infliximab	Neutropenic sepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	1	632	22501	2983021	0.114	0.026	0.358	0.081	10.441	0.081	0.001	-1.5317427	-2.1715568
Infliximab	Neutrophil count	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	6	138	22496	2983515	1.503	0.759	2.737	1.906	2.477	1.908	0.116	1.7413322	0.40746311
Infliximab	Neutrophil count abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	267	22501	2983386	0.245	0.057	0.766	0.197	3.346	0.197	0.067	-0.5988433	-1.4064971
Infliximab	Neutrophil count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	15	2522	22487	2981131	0.351	0.227	0.524	0.343	18.712	0.343	0.0000152	-0.3332818	-1.0469691
Infliximab	Neutrophil count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	18	1008	22484	2982645	1.04	0.699	1.5	1.081	0.107	1.081	0.743	1.11891766	0.03922071
Infliximab	Neutrophil hypersegmented morphology present	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	7	22501	2983646	1.282	0.295	4.031	14.698	10.167	14.698	0.001	0.90525186	0.24842136
Infliximab	Neutrophil morphology abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	17	22501	2983636	1.105	0.256	3.456	4.176	2.054	4.176	0.152	0.80679534	0.09984533
Infliximab	Neutrophil percentage decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	181	22501	2983472	0.367	0.085	1.147	0.324	1.376	0.324	0.241	-0.251135	-1.0023934
Infliximab	Neutrophil percentage increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	12	290	22490	2983363	1.997	1.228	3.105	2.416	9.319	2.418	0.002	1.98433767	0.69164605
Infliximab	Neutrophil toxic granulation present	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	41	22501	2983612	0.862	0.199	2.691	1.557	0.19	1.557	0.663	0.59475445	-0.1485
Infliximab	Neutrophilia	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	9	471	22493	2983182	1.445	0.825	2.388	1.668	2.336	1.669	0.126	1.11144019	0.36810932
Infliximab	Night sweats	Apocrine and eccrine gland disorders	Skin appendage conditions	Skin	1968-2006	55	2268	22447	2981385	1.451	1.158	1.799	1.497	8.804	1.498	0.003	1.59469615	0.37225297
Infliximab	Nightmare	Parasomnias	Sleep disorders and disturbances	Psych	1968-2006	4	3508	22498	2980145	0.076	0.033	0.155	0.067	51.614	0.067	6.755e-13	-2.4608237	-2.5770219
Infliximab	Nipple disorder	Breast disorders NEC	Breast disorders	Repro	1968-2006	1	104	22501	2983549	0.535	0.124	1.671	0.571	0.311	0.571	0.577	0.15241245	-0.6254885
Infliximab	Nitrite urine	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	5	22501	2983648	1.212	0.28	3.797	8.001	4.965	8.002	0.026	0.92577585	0.19227189
Infliximab	Nitrite urine present	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	2	46	22500	2983607	1.2	0.389	3.01	2.101	1.08	2.101	0.299	1.13124153	0.18232156
Infliximab	No adverse drug effect	Adverse effect absent	General system disorders NEC	Genrl	1968-2006	29	1286	22473	2982367	1.058	0.775	1.419	1.086	0.194	1.086	0.66	1.45671274	0.05638033
Infliximab	No adverse effect	Adverse effect absent	General system disorders NEC	Genrl	1968-2006	12	2503	22490	2981150	0.362	0.223	0.563	0.355	14.158	0.354	0.0001681	-0.6208988	-1.0161111
Infliximab	No therapeutic response	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	2	175	22500	2983478	0.692	0.224	1.734	0.792	0.108	0.792	0.742	0.35686995	-0.3681693
Infliximab	Nocardiosis	Nocardia infections	Bacterial infectious disorders	Infec	1968-2006	37	106	22465	2983547	16.023	11.973	20.958	23.387	553.301	23.438	0	4.18711958	2.77402519
Infliximab	Nocturia	Urinary tract signs and symptoms NEC	Urinary tract signs and symptoms	Renal	1968-2006	5	1803	22497	2981850	0.413	0.196	0.79	0.405	4.331	0.405	0.037	-1.2880523	-0.8843077
Infliximab	Nocturnal dyspnoea	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	3	86	22499	2983567	1.219	0.473	2.694	1.735	0.881	1.735	0.348	1.2525631	0.19803085
Infliximab	Nodal arrhythmia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	2	596	22500	2983057	0.409	0.132	1.024	0.392	1.864	0.392	0.172	-0.8793435	-0.8940401
Infliximab	Nodal osteoarthritis	Osteoarthropathies	Joint disorders	Musc	1968-2006	2	13	22500	2983640	1.908	0.615	4.84	12.05	14.817	12.05	0.0001184	1.4205959	0.64605557
Infliximab	Nodular vasculitis	Skin vasculitides	Skin vascular abnormalities	Skin	1968-2006	2	15	22500	2983638	1.851	0.597	4.681	9.734	12.141	9.734	0.0004932	1.40130667	0.61572603
Infliximab	Nodule	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	10	315	22492	2983338	1.559	0.916	2.519	1.82	3.488	1.821	0.062	1.66908465	0.44404459
Infliximab	Nodule on extremity	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	77	22501	2983576	0.538	0.124	1.679	0.576	0.303	0.576	0.582	0.3256836	-0.6198967
Infliximab	Non-Hodgkins lymphoma	Non-Hodgkins lymphomas NEC	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	137	671	22365	2982982	9.64	8.272	11.187	12.715	1136.001	12.789	0	4.28011166	2.26592111
Infliximab	Non-Hodgkins lymphoma recurrent	Non-Hodgkins lymphomas NEC	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	2	36	22500	2983617	1.34	0.434	3.362	2.733	2.045	2.733	0.153	1.2129632	0.29266961
Infliximab	Non-Hodgkins lymphoma stage I	Non-Hodgkins lymphomas NEC	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	2	5	22500	2983648	2.071	0.66	5.344	30.173	27.401	30.173	1.653e-7	1.50043989	0.72803158
Infliximab	Non-Hodgkins lymphoma stage II	Non-Hodgkins lymphomas NEC	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	1	5	22501	2983648	1.218	0.281	3.819	8.558	5.293	8.558	0.021	0.92577585	0.19721017
Infliximab	Non-Hodgkins lymphoma stage III	Non-Hodgkins lymphomas NEC	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	1	7	22501	2983646	1.17	0.27	3.663	5.416	3.488	5.416	0.062	0.90525186	0.15700375
Infliximab	Non-Hodgkins lymphoma stage IV	Non-Hodgkins lymphomas NEC	Lymphomas non-Hodgkins unspecified histology	Neopl	1968-2006	9	13	22493	2983640	13.341	4.61	28.68	42.07	167.269	42.11	2.922e-38	3.0911486	2.590842
Infliximab	Non-cardiac chest pain	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	3	427	22499	2983226	0.521	0.202	1.151	0.526	1.241	0.526	0.265	-0.0878382	-0.6520052
Infliximab	Non-cardiogenic pulmonary oedema	Pulmonary oedemas	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	2	85	22500	2983568	1.089	0.353	2.731	1.709	0.554	1.71	0.457	0.85054745	0.08525984
Infliximab	Non-small cell lung cancer	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	23	368	22479	2983285	2.973	2.094	4.124	3.588	39.579	3.592	3.151e-10	2.60060513	1.08957154
Infliximab	Non-small cell lung cancer metastatic	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	4	47	22498	2983606	2.224	0.97	4.53	4.777	10.521	4.777	0.001	1.84456698	0.79930738
Infliximab	Non-small cell lung cancer recurrent	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	13	22501	2983640	1.112	0.257	3.478	4.34	2.177	4.34	0.14	0.84537553	0.1061602
Infliximab	Non-small cell lung cancer stage I	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	7	22501	2983646	1.191	0.275	3.73	6.847	4.142	6.847	0.042	0.90525186	0.17479329
Infliximab	Non-small cell lung cancer stage III	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	2	22501	2983651	1.316	0.302	4.152	49.381	16.042	49.381	0.00006197	0.95711984	0.27459683
Infliximab	Non-small cell lung cancer stage IIIB	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	13	22500	2983640	1.797	0.581	4.536	7.11	10.077	7.11	0.002	1.4205959	0.58611861
Infliximab	Non-small cell lung cancer stage IV	Non-small cell neoplasms malignant of the respiratory tract cell type specified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	3	59	22499	2983594	1.56	0.606	3.45	2.763	3.113	2.763	0.078	1.43912756	0.44468582
Infliximab	Nonspecific reaction	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	3	393	22499	2983260	0.491	0.191	1.084	0.491	1.56	0.491	0.212	0.00194755	-0.7113112
Infliximab	Normochromic normocytic anaemia	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	9	777	22493	2982876	0.869	0.496	1.437	0.915	0.069	0.915	0.793	0.52758077	-0.1404122
Infliximab	Nose deformity	Musculoskeletal and connective tissue deformities of skull, face and buccal cavity	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	1	46	22501	2983607	0.879	0.203	2.744	1.649	0.24	1.649	0.624	0.5542459	-0.1289704
Infliximab	Nosocomial infection	Infectious transmissions	Ancillary infectious topics	Infec	1968-2006	9	356	22493	2983297	1.52	0.867	2.512	1.772	2.961	1.772	0.085	1.4109138	0.41871033
Infliximab	Nuclear magnetic resonance imaging abnormal	Imaging procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	19	827	22483	2982826	1.41	0.958	2.016	1.514	3.183	1.514	0.074	1.4363692	0.3435897
Infliximab	Nuclear magnetic resonance imaging brain abnormal	Central nervous system imaging procedures	Neurological and special sense investigations	Inv	1968-2006	31	603	22471	2983050	2.425	1.793	3.22	2.722	31.544	2.725	1.95e-8	2.46638811	0.88583152
Infliximab	Nucleated red cells	Red blood cell abnormal findings NEC	Red blood cell disorders	Blood	1968-2006	1	8	22501	2983645	1.272	0.293	3.997	17.337	9.071	17.337	0.003	0.89509832	0.24059046
Infliximab	Nystagmus	Cerebellar coordination and balance disturbances	Neurological disorders NEC	Nerv	1968-2006	8	2210	22494	2981443	0.48	0.265	0.816	0.477	4.538	0.477	0.033	-0.9796841	-0.7339692
Infliximab	Obesity	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	5	1044	22497	2982609	0.378	0.179	0.721	0.365	5.423	0.365	0.02	-0.5723991	-0.9728611
Infliximab	Obliterative bronchiolitis	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	18	166	22484	2983487	4.084	2.742	5.909	5.896	63.299	5.9	1.776e-15	2.98768252	1.4070769
Infliximab	Obsessive-compulsive disorder	Anxiety disorders NEC (incl obsessive compulsive disorder)	Anxiety disorders and symptoms	Psych	1968-2006	3	869	22499	2982784	0.214	0.083	0.474	0.193	10.074	0.193	0.002	-0.9233702	-1.5417793
Infliximab	Obstruction	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	12	442	22490	2983211	1.654	1.017	2.572	1.905	4.891	1.906	0.027	1.55243006	0.5031966
Infliximab	Obstruction gastric	Gastric and pyloric stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	2	210	22500	2983443	0.753	0.244	1.887	0.899	0.023	0.899	0.88	0.20280541	-0.2836901
Infliximab	Obstructive airways disorder	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	25	1094	22477	2982559	1.553	1.109	2.126	1.661	6.275	1.662	0.012	1.46008899	0.44018854
Infliximab	Obstructive uropathy	Renal obstructive disorders	Renal disorders (excl nephropathies)	Renal	1968-2006	6	743	22496	2982910	0.66	0.333	1.202	0.682	0.877	0.682	0.349	0.07227126	-0.4155154
Infliximab	Occult blood positive	Faecal analyses NEC	Gastrointestinal investigations	Inv	1968-2006	18	1184	22484	2982469	1.068	0.718	1.541	1.114	0.204	1.114	0.651	0.91497111	0.06578774
Infliximab	Occupational exposure to toxic agent	Occupational environmental problems	Environmental issues	SocCi	1968-2006	1	32	22501	2983621	0.838	0.194	2.615	1.446	0.129	1.446	0.719	0.67066536	-0.1767372
Infliximab	Ocular discomfort	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	2	61	22500	2983592	1.155	0.374	2.896	1.92	0.841	1.92	0.359	1.01673229	0.14410034
Infliximab	Ocular hyperaemia	Ocular infections, inflammations and associated manifestations	Ocular infections, irritations and inflammations	Eye	1968-2006	24	1894	22478	2981759	0.877	0.622	1.208	0.893	0.306	0.892	0.58	0.69129312	-0.1312483
Infliximab	Ocular icterus	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	1	350	22501	2983303	0.209	0.048	0.652	0.159	4.398	0.159	0.036	-0.8699215	-1.565421
Infliximab	Ocular myasthenia	Ocular nerve and muscle disorders	Ocular neuromuscular disorders	Eye	1968-2006	1	22	22501	2983631	0.944	0.218	2.948	2.079	0.514	2.079	0.473	0.75997701	-0.0576291
Infliximab	Ocular neoplasm	Ocular neoplasms malignancy unspecified	Ocular neoplasms	Neopl	1968-2006	1	29	22501	2983624	0.876	0.203	2.734	1.61	0.231	1.61	0.631	0.69688322	-0.1323892
Infliximab	Ocular vascular disorder	Ocular bleeding and vascular disorders NEC	Ocular haemorrhages and vascular disorders NEC	Eye	1968-2006	2	148	22500	2983505	0.624	0.202	1.564	0.679	0.292	0.679	0.589	0.48808539	-0.4716049
Infliximab	Oculogyration	Ocular nerve and muscle disorders	Ocular neuromuscular disorders	Eye	1968-2006	1	1213	22501	2982440	0.312	0.072	0.976	0.263	2.048	0.263	0.152	-2.345874	-1.1647521
Infliximab	Odontogenic cyst	Dental disorders congenital	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	0	22501	2983653	1.345	0.308	4.256	1075.772	51.692	1083.348	6.493e-13	0.97840063	0.29639401
Infliximab	Odynophagia	Oral soft tissue pain and paraesthesia	Oral soft tissue conditions	Gastr	1968-2006	15	569	22487	2983084	1.483	0.96	2.21	1.629	3.514	1.629	0.061	1.56358126	0.39406706
Infliximab	Oedema	Oedema NEC	General system disorders NEC	Genrl	1968-2006	104	24347	22398	2959306	0.769	0.653	0.901	0.767	7.225	0.766	0.007	-0.8321584	-0.2626643
Infliximab	Oedema mouth	Oral soft tissue swelling and oedema	Oral soft tissue conditions	Gastr	1968-2006	12	831	22490	2982822	0.927	0.57	1.441	0.969	0.012	0.969	0.914	0.81930436	-0.0758017
Infliximab	Oedema peripheral	Oedema NEC	General system disorders NEC	Genrl	1968-2006	317	42230	22185	2941423	0.855	0.779	0.937	0.853	8.014	0.851	0.005	-0.0380915	-0.1566538
Infliximab	Oesophageal adenocarcinoma	Oesophageal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	3	31	22499	2983622	2.448	0.943	5.505	10.247	21.096	10.25	4.368e-6	1.66203108	0.89527136
Infliximab	Oesophageal cancer metastatic	Oesophageal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	3	10	22499	2983643	2.614	0.999	5.976	16.135	29.127	16.135	6.778e-8	1.85518405	0.96088162
Infliximab	Oesophageal candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	33	415	22469	2983238	4.218	3.147	5.56	5.297	102.348	5.304	4.658e-24	2.95427116	1.43936108
Infliximab	Oesophageal carcinoma	Oesophageal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	17	289	22485	2983364	3.099	2.059	4.517	3.957	34.952	3.96	3.379e-9	2.44063514	1.13107948
Infliximab	Oesophageal discomfort	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	1	53	22501	2983600	0.69	0.16	2.152	0.915	0.008	0.915	0.93	0.49937916	-0.3710637
Infliximab	Oesophageal disorder	Oesophageal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	10	787	22492	2982866	0.863	0.507	1.393	0.902	0.104	0.902	0.747	0.64792458	-0.1473406
Infliximab	Oesophageal haemorrhage	Gastric and oesophageal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	3	471	22499	2983182	0.866	0.337	1.914	1.022	0.001	1.022	0.97	-0.1963106	-0.1438704
Infliximab	Oesophageal neoplasm	Oesophageal neoplasms malignancy unspecified	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	3	24	22499	2983629	2.255	0.873	5.026	7.082	14.569	7.082	0.0001351	1.72358648	0.81314997
Infliximab	Oesophageal obstruction	Oesophageal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	2	134	22500	2983519	1.023	0.332	2.565	1.503	0.328	1.503	0.567	0.56113044	0.02273949
Infliximab	Oesophageal operation	Oesophageal therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	7	22501	2983646	1.21	0.279	3.792	8.456	4.902	8.456	0.027	0.90525186	0.19062036
Infliximab	Oesophageal pain	Gastrointestinal and abdominal pains (excl oral and throat)	Gastrointestinal signs and symptoms	Gastr	1968-2006	4	433	22498	2983220	0.593	0.259	1.206	0.613	0.97	0.613	0.325	0.21627865	-0.5225609
Infliximab	Oesophageal spasm	Gastrointestinal spastic and hypermotility disorders	Gastrointestinal motility and defaecation conditions	Gastr	1968-2006	5	296	22497	2983357	0.953	0.452	1.821	1.074	0.025	1.074	0.874	0.87217439	-0.0481404
Infliximab	Oesophageal squamous cell carcinoma	Oesophageal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	4	20	22498	2983633	3.038	1.306	6.392	12.621	32.513	12.626	1.184e-8	2.07272126	1.1111994
Infliximab	Oesophageal stenosis	Oesophageal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	4	719	22498	2982934	0.713	0.311	1.448	0.764	0.285	0.764	0.593	-0.3700055	-0.3382739
Infliximab	Oesophageal ulcer	Oesophageal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	16	1685	22486	2981968	1.208	0.793	1.779	1.282	0.973	1.282	0.324	0.29628542	0.1889661
Infliximab	Oesophageal ulcer haemorrhage	Oesophageal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	123	22501	2983530	0.501	0.116	1.565	0.517	0.448	0.517	0.503	0.04186259	-0.6911492
Infliximab	Oesophageal varices haemorrhage	Gastric and oesophageal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	4	242	22498	2983411	1.011	0.441	2.053	1.2	0.131	1.2	0.718	0.80437666	0.01093994
Infliximab	Oesophagitis	Oesophagitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	42	5351	22460	2978302	1.147	0.885	1.465	1.173	1.043	1.173	0.307	0.0423835	0.13714984
Infliximab	Oesophagitis haemorrhagic	Oesophagitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	1	38	22501	2983615	0.861	0.199	2.687	1.544	0.187	1.544	0.666	0.61961696	-0.1496608
Infliximab	Oesophagitis ulcerative	Oesophageal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	3	105	22499	2983548	1.066	0.414	2.357	1.395	0.319	1.396	0.572	1.13438467	0.06391333
Infliximab	Oesophagogastric fundoplasty	Gastric therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	23	22501	2983630	0.972	0.225	3.035	2.311	0.672	2.311	0.412	0.75079293	-0.0283995
Infliximab	Oestrogen receptor assay positive	Reproductive hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	3	872	22499	2982781	0.213	0.083	0.471	0.192	10.196	0.191	0.001	-0.9276693	-1.5464631
Infliximab	Off label use	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	4	615	22498	2983038	0.403	0.176	0.818	0.392	3.739	0.392	0.053	-0.1832157	-0.9088187
Infliximab	Oligodendroglioma	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	1	19	22501	2983634	1.094	0.253	3.421	3.952	1.878	3.952	0.171	0.78788532	0.0898407
Infliximab	Oligomenorrhoea	Menstruation with decreased bleeding	Menstrual cycle and uterine bleeding disorders	Repro	1968-2006	1	992	22501	2982661	0.08	0.018	0.252	0.057	16.152	0.056	0.00005847	-2.0873491	-2.5257286
Infliximab	Oliguria	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	11	4190	22491	2979463	0.365	0.22	0.578	0.358	12.642	0.357	0.0003772	-1.4478625	-1.0078579
Infliximab	Oncocytoma	Neoplasms benign site unspecified NEC	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	1	3	22501	2983650	1.31	0.301	4.127	28.937	14.421	28.937	0.0001462	0.946596	0.27002714
Infliximab	Onychoclasis	Nail and nail bed conditions (excl infections and infestations)	Skin appendage conditions	Skin	1968-2006	1	215	22501	2983438	0.356	0.082	1.111	0.31	1.502	0.31	0.22	-0.3987615	-1.0328245
Infliximab	Onychomadesis	Nail and nail bed conditions (excl infections and infestations)	Skin appendage conditions	Skin	1968-2006	4	126	22498	2983527	1.197	0.523	2.432	1.531	0.702	1.531	0.402	1.33057012	0.17981843
Infliximab	Onychomycosis	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	10	193	22492	2983460	2.509	1.473	4.054	3.482	15.908	3.483	0.00006648	2.1153498	0.91988427
Infliximab	Oophorectomy	Ovarian therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	96	22501	2983557	0.636	0.147	1.986	0.778	0.061	0.778	0.806	0.20161885	-0.4525567
Infliximab	Oophoritis	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	12	22501	2983641	1.156	0.267	3.619	5.412	3.099	5.412	0.078	0.85518395	0.14496577
Infliximab	Open fracture	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	1	54	22501	2983599	0.674	0.156	2.104	0.873	0.018	0.873	0.893	0.49170863	-0.3945252
Infliximab	Open wound	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	12	242	22490	2983411	2.129	1.309	3.312	2.65	11.29	2.652	0.001	2.15279802	0.75565239
Infliximab	Ophthalmoplegia	Ocular nerve and muscle disorders	Ocular neuromuscular disorders	Eye	1968-2006	6	341	22496	2983312	1.352	0.682	2.462	1.638	1.466	1.638	0.226	0.94939499	0.30158498
Infliximab	Opiates positive	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	1	47	22501	2983606	0.846	0.196	2.64	1.475	0.147	1.475	0.702	0.54627889	-0.1672359
Infliximab	Opportunistic infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	20	109	22482	2983544	6.305	4.215	9.538	10.468	140.531	10.482	2.037e-32	3.40644731	1.84134297
Infliximab	Optic atrophy	Optic disc abnormalities NEC	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	5	480	22497	2983173	0.924	0.438	1.765	1.033	0.005	1.034	0.942	0.36276222	-0.0790432
Infliximab	Optic disc disorder	Optic disc abnormalities NEC	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	3	95	22499	2983558	1.433	0.557	3.169	2.311	2.109	2.311	0.146	1.19537591	0.35977015
Infliximab	Optic ischaemic neuropathy	Optic nerve bleeding and vascular disorders	Ocular haemorrhages and vascular disorders NEC	Eye	1968-2006	8	597	22494	2983056	0.755	0.417	1.282	0.783	0.466	0.783	0.495	0.69187971	-0.2810375
Infliximab	Optic nerve disorder	Visual pathway disorders	Vision disorders	Eye	1968-2006	4	356	22498	2983297	0.654	0.286	1.329	0.688	0.556	0.688	0.456	0.42545506	-0.4246479
Infliximab	Optic nerve sheath haemorrhage	Optic nerve bleeding and vascular disorders	Ocular haemorrhages and vascular disorders NEC	Eye	1968-2006	1	25	22501	2983628	1.018	0.236	3.181	2.779	1.013	2.779	0.314	0.7325983	0.01783992
Infliximab	Optic neuritis	Optic nerve disorders NEC	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	57	1910	22445	2981743	3.451	2.765	4.266	3.923	113.275	3.931	1.878e-26	1.87135713	1.23866404
Infliximab	Optic neuritis retrobulbar	Neurologic visual problems NEC	Neurological disorders of the eye	Nerv	1968-2006	4	208	22498	2983445	1.439	0.628	2.924	2.033	1.984	2.033	0.159	0.93977161	0.36394843
Infliximab	Optic neuropathy	Visual pathway disorders	Vision disorders	Eye	1968-2006	7	298	22495	2983355	1.262	0.669	2.211	1.463	0.993	1.463	0.319	1.27399286	0.23269776
Infliximab	Oral candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	41	2711	22461	2980942	1.637	1.26	2.098	1.719	11.871	1.72	0.001	0.94723602	0.4928653
Infliximab	Oral discomfort	Oral soft tissue signs and symptoms	Oral soft tissue conditions	Gastr	1968-2006	3	976	22499	2982677	0.232	0.09	0.513	0.212	8.82	0.212	0.003	-1.0693011	-1.4610179
Infliximab	Oral dysaesthesia	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	17	22501	2983636	1.004	0.232	3.135	2.502	0.897	2.502	0.344	0.80679534	0.00399202
Infliximab	Oral fungal infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	6	198	22496	2983455	1.237	0.624	2.252	1.465	0.851	1.465	0.356	1.45899166	0.21268909
Infliximab	Oral hairy leukoplakia	Epstein-Barr viral infections	Viral infectious disorders	Infec	1968-2006	1	7	22501	2983646	1.247	0.288	3.915	10.382	6.984	10.382	0.008	0.90525186	0.22074067
Infliximab	Oral infection	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	127	22501	2983526	0.428	0.099	1.337	0.404	0.863	0.404	0.353	0.0196303	-0.8486321
Infliximab	Oral intake reduced	Appetite disorders	Appetite and general nutritional disorders	Metab	1968-2006	33	3838	22469	2979815	0.548	0.409	0.722	0.545	12.456	0.544	0.0004166	0.16904879	-0.60148
Infliximab	Oral lichen planus	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	2	32	22500	2983621	1.58	0.512	3.97	4.587	4.864	4.587	0.027	1.24699348	0.45742485
Infliximab	Oral mucosal blistering	Oral soft tissue signs and symptoms	Oral soft tissue conditions	Gastr	1968-2006	5	560	22497	2983093	0.557	0.264	1.064	0.565	1.655	0.565	0.198	0.1872625	-0.58519
Infliximab	Oral mucosal disorder	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	109	22501	2983544	0.534	0.123	1.665	0.575	0.317	0.575	0.574	0.12248935	-0.6273594
Infliximab	Oral pain	Oral soft tissue pain and paraesthesia	Oral soft tissue conditions	Gastr	1968-2006	6	1564	22496	2982089	0.289	0.146	0.527	0.277	11.297	0.277	0.001	-0.8768844	-1.2413286
Infliximab	Oral pruritus	Oral soft tissue signs and symptoms	Oral soft tissue conditions	Gastr	1968-2006	2	77	22500	2983576	0.978	0.317	2.451	1.39	0.207	1.39	0.649	0.90384367	-0.0222456
Infliximab	Oral soft tissue disorder	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	3	535	22499	2983118	0.457	0.178	1.011	0.454	1.964	0.454	0.161	-0.3408229	-0.7830719
Infliximab	Orbital oedema	Orbital structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	74	22501	2983579	0.664	0.154	2.072	0.847	0.027	0.847	0.869	0.34628598	-0.4094731
Infliximab	Orchitis	Male reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	3	157	22499	2983496	1.434	0.557	3.171	2.305	2.108	2.306	0.146	0.85312306	0.36046774
Infliximab	Organ failure	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	8	1297	22494	2982356	0.315	0.174	0.535	0.305	12.7	0.305	0.0003657	-0.2702634	-1.1551826
Infliximab	Oropharyngeal cancer stage unspecified	Oropharyngeal, nasopharyngeal and tonsillar neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	19	22501	2983634	1.046	0.242	3.269	3.03	1.279	3.03	0.258	0.78788532	0.04497337
Infliximab	Oropharyngeal candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	8	32	22494	2983621	4.372	2.363	7.855	11.544	57.919	11.548	2.731e-14	2.78120756	1.47522057
Infliximab	Oropharyngeal neoplasm	Lip and oral cavity neoplasms malignancy unspecified	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	2	22500	2983651	2.139	0.676	5.596	51.213	35.524	51.213	2.519e-9	1.53155852	0.76033843
Infliximab	Oropharyngeal spasm	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	49	22501	2983604	0.784	0.181	2.448	1.218	0.038	1.218	0.846	0.53047566	-0.2433463
Infliximab	Oropharyngeal swelling	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	16	784	22486	2982869	0.919	0.603	1.353	0.949	0.044	0.949	0.834	1.27131345	-0.0844692
Infliximab	Oropharyngitis fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	2	25	22500	2983628	1.499	0.486	3.764	3.817	3.707	3.817	0.054	1.30854889	0.40479822
Infliximab	Orthopedic procedure	Bone therapeutic procedures NEC	Bone and joint therapeutic procedures	Surg	1968-2006	4	15	22498	2983638	3.02	1.299	6.341	13.016	31.954	13.02	1.579e-8	2.11923763	1.10525683
Infliximab	Orthopnoea	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	11	772	22491	2982881	1.101	0.662	1.742	1.184	0.303	1.184	0.582	0.79533165	0.09621886
Infliximab	Orthostatic hypotension	Vascular hypotensive disorders	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	15	6032	22487	2977621	0.397	0.257	0.591	0.39	14.212	0.389	0.0001633	-1.5455657	-0.923819
Infliximab	Osteitis	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	7	235	22495	2983418	1.667	0.884	2.922	2.115	3.93	2.116	0.047	1.49773455	0.5110256
Infliximab	Osteoarthritis	Osteoarthropathies	Joint disorders	Musc	1968-2006	47	5338	22455	2978315	1.206	0.945	1.522	1.236	2.049	1.236	0.152	0.20317736	0.1873091
Infliximab	Osteochondrosis	Cartilage disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	3	127	22499	2983526	1.224	0.476	2.707	1.743	0.903	1.743	0.342	1.00864178	0.20212418
Infliximab	Osteolysis	Metabolic bone disorders	Bone disorders (excl congenital and fractures)	Musc	1968-2006	5	241	22497	2983412	1.262	0.598	2.411	1.557	0.962	1.557	0.327	1.06741138	0.23269776
Infliximab	Osteomyelitis	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	57	1697	22445	2981956	2.224	1.782	2.749	2.372	43.084	2.375	5.244e-11	2.02570875	0.79930738
Infliximab	Osteomyelitis acute	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	1	35	22501	2983618	0.916	0.212	2.86	1.865	0.379	1.865	0.538	0.64491541	-0.0877389
Infliximab	Osteomyelitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	0	22500	2983653	2.831	0.751	29.728	1823.764	234.004	1836.634	0	1.55268351	1.04063001
Infliximab	Osteomyelitis chronic	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	1	101	22501	2983552	0.567	0.131	1.771	0.633	0.208	0.633	0.649	0.17066877	-0.567396
Infliximab	Osteonecrosis	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	25	6375	22477	2977278	0.269	0.192	0.368	0.262	52.141	0.262	5.166e-13	-0.9254235	-1.3130439
Infliximab	Osteopenia	Metabolic bone disorders	Bone disorders (excl congenital and fractures)	Musc	1968-2006	8	445	22494	2983208	0.938	0.518	1.593	1.007	0	1.007	0.985	1.02437167	-0.0640053
Infliximab	Osteoporosis	Metabolic bone disorders	Bone disorders (excl congenital and fractures)	Musc	1968-2006	41	2398	22461	2981255	1.321	1.016	1.693	1.365	3.869	1.366	0.049	1.11303184	0.27838903
Infliximab	Osteoporotic fracture	Pathological fractures and complications	Fractures	Musc	1968-2006	7	190	22495	2983463	2.504	1.327	4.393	3.975	14.192	3.977	0.0001651	1.681869	0.91788945
Infliximab	Osteosclerosis	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	1	73	22501	2983580	0.735	0.17	2.293	1.047	0.002	1.047	0.964	0.35321934	-0.3078848
Infliximab	Osteotomy	Bone therapeutic procedures NEC	Bone and joint therapeutic procedures	Surg	1968-2006	2	36	22500	2983617	1.543	0.5	3.876	4.088	4.282	4.088	0.039	1.2129632	0.43372857
Infliximab	Otitis externa	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	5	238	22497	2983415	1.732	0.821	3.309	2.475	4.243	2.476	0.039	1.07885996	0.54927681
Infliximab	Otitis media	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	16	1395	22486	2982258	1.912	1.255	2.816	2.178	9.77	2.179	0.002	0.54465859	0.64814981
Infliximab	Otitis media acute	Ear infections	Infections - pathogen class unspecified	Infec	1968-2006	2	53	22500	2983600	1.312	0.425	3.292	2.504	1.813	2.504	0.178	1.07667128	0.27155269
Infliximab	Otorrhoea	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	2	104	22500	2983549	0.948	0.307	2.377	1.311	0.143	1.311	0.706	0.7313407	-0.0534008
Infliximab	Otosclerosis	Middle ear disorders NEC	Middle ear disorders (excl congenital)	Ear	1968-2006	1	34	22501	2983619	0.838	0.194	2.616	1.441	0.129	1.441	0.719	0.65344776	-0.1767372
Infliximab	Ototoxicity	Ear disorders NEC	Aural disorders NEC	Ear	1968-2006	1	217	22501	2983436	0.364	0.084	1.135	0.325	1.418	0.325	0.234	-0.4069925	-1.0106014
Infliximab	Ovarian abscess	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	2	16	22500	2983637	1.822	0.588	4.603	8.717	10.974	8.72	0.001	1.3917579	0.5999348
Infliximab	Ovarian adenoma	Ovarian neoplasms benign	Reproductive neoplasms female benign	Neopl	1968-2006	2	30	22500	2983623	1.417	0.459	3.555	3.198	2.756	3.198	0.097	1.26431441	0.34854196
Infliximab	Ovarian cancer	Ovarian neoplasms malignant (excl germ cell)	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	49	1385	22453	2982268	1.58	1.243	1.984	1.652	12.063	1.655	0.001	2.07973117	0.45742485
Infliximab	Ovarian cancer metastatic	Ovarian neoplasms malignant (excl germ cell)	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	8	66	22494	2983587	3.304	1.819	5.639	6.184	29.658	6.187	5.155e-8	2.52314556	1.19513386
Infliximab	Ovarian cyst	Ovarian and fallopian tube cysts and neoplasms	Ovarian and fallopian tube disorders	Repro	1968-2006	32	1364	22470	2982289	1.534	1.14	2.029	1.624	7.286	1.626	0.007	1.51568308	0.4278787
Infliximab	Ovarian cyst ruptured	Ovarian and fallopian tube cysts and neoplasms	Ovarian and fallopian tube disorders	Repro	1968-2006	3	124	22499	2983529	1.044	0.406	2.309	1.348	0.259	1.348	0.611	1.02515681	0.04305949
Infliximab	Ovarian disorder	Ovarian and fallopian tube disorders NEC	Ovarian and fallopian tube disorders	Repro	1968-2006	4	1235	22498	2982418	1.183	0.517	2.404	1.5	0.646	1.501	0.422	-1.0504757	0.16805358
Infliximab	Ovarian epithelial cancer	Ovarian neoplasms malignant (excl germ cell)	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	10	24	22492	2983629	6.188	3.288	13.594	17.47	102.663	17.482	3.974e-24	3.12146341	1.82261193
Infliximab	Ovarian epithelial cancer stage IV	Ovarian neoplasms malignant (excl germ cell)	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	1	4	22501	2983649	1.218	0.281	3.819	8.506	5.317	8.506	0.021	0.93614837	0.19721017
Infliximab	Ovarian failure	Ovarian and fallopian tube disorders NEC	Ovarian and fallopian tube disorders	Repro	1968-2006	1	48	22501	2983605	0.783	0.181	2.443	1.207	0.036	1.207	0.85	0.53835564	-0.2446226
Infliximab	Ovarian granulosa-theca cell tumour	Female reproductive neoplasms unspecified malignancy	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	1	4	22501	2983649	1.293	0.298	4.068	25.025	11.569	25.025	0.001	0.93614837	0.2569651
Infliximab	Ovarian mass	Ovarian and fallopian tube disorders NEC	Ovarian and fallopian tube disorders	Repro	1968-2006	4	36	22498	2983617	2.388	1.041	4.873	5.871	13.547	5.872	0.0002327	1.9332102	0.8704562
Infliximab	Ovarian necrosis	Ovarian and fallopian tube disorders NEC	Ovarian and fallopian tube disorders	Repro	1968-2006	1	7	22501	2983646	1.213	0.28	3.802	8.109	5.049	8.11	0.025	0.90525186	0.19309663
Infliximab	Ovarian neoplasm	Female reproductive neoplasms unspecified malignancy	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	8	113	22494	2983540	2.624	1.448	4.46	4.101	16.559	4.103	0.00004716	2.22869115	0.96469987
Infliximab	Ovarian rupture	Ovarian and fallopian tube disorders NEC	Ovarian and fallopian tube disorders	Repro	1968-2006	1	8	22501	2983645	1.268	0.292	3.985	13.11	8.69	13.11	0.003	0.89509832	0.23744086
Infliximab	Ovarian torsion	Ovarian and fallopian tube disorders NEC	Ovarian and fallopian tube disorders	Repro	1968-2006	1	33	22501	2983620	0.892	0.206	2.786	1.733	0.287	1.733	0.592	0.66203088	-0.1142891
Infliximab	Overdose	Overdoses	Medication errors	Inj&P	1968-2006	17	27595	22485	2956058	0.069	0.046	0.101	0.066	227.81	0.065	0	-3.5525672	-2.6736488
Infliximab	Overgrowth bacterial	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	3	23	22499	2983630	2.24	0.867	4.99	7.604	14.087	7.604	0.0001746	1.73259846	0.80647587
Infliximab	Oxygen consumption decreased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	14	22501	2983639	1.124	0.26	3.514	4.198	2.371	4.198	0.124	0.83563334	0.11689375
Infliximab	Oxygen saturation	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	21	22501	2983632	1.075	0.249	3.361	3.405	1.618	3.406	0.203	0.76921993	0.07232066
Infliximab	Oxygen saturation abnormal	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	4	82	22498	2983571	1.935	0.844	3.935	3.593	6.479	3.593	0.011	1.59406879	0.66010733
Infliximab	Oxygen saturation decreased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	162	5773	22340	2977880	1.897	1.664	2.154	1.956	72.89	1.964	1.371e-17	1.8296696	0.64027369
Infliximab	Oxygen supplementation	Respiratory tract therapeutic procedures NEC	Respiratory tract therapeutic procedures	Surg	1968-2006	1	20	22501	2983633	1.031	0.239	3.222	2.941	1.132	2.941	0.287	0.77852244	0.03052921
Infliximab	PCO2	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	7	61	22495	2983592	2.556	1.354	4.485	4.149	15.038	4.159	0.0001054	2.39553503	0.93844354
Infliximab	PCO2 decreased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	5	457	22497	2983196	0.571	0.271	1.091	0.58	1.486	0.58	0.223	0.41743684	-0.5603661
Infliximab	PCO2 increased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	241	22501	2983412	0.286	0.066	0.894	0.236	2.47	0.236	0.116	-0.5022673	-1.2517635
Infliximab	PO2	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	3	37	22499	2983616	1.606	0.624	3.554	2.908	3.549	2.91	0.06	1.61128199	0.47374662
Infliximab	PO2 abnormal	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	42	22501	2983611	0.764	0.177	2.386	1.143	0.018	1.143	0.894	0.58656124	-0.2691875
Infliximab	PO2 decreased	Blood gas and acid base analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	21	1224	22481	2982429	1.377	0.954	1.936	1.463	2.976	1.463	0.084	1.08073967	0.31990722
Infliximab	POEMS syndrome	Immunodeficiency disorders NEC	Immunodeficiency syndromes	Immun	1968-2006	1	3	22501	2983650	1.294	0.298	4.073	20.952	11.757	20.952	0.001	0.946596	0.2577382
Infliximab	Pacemaker complication	Device related complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	41	22500	2983612	1.519	0.492	3.816	3.961	3.952	3.961	0.047	1.17152386	0.41805222
Infliximab	Pachymeningitis	Meningitis NEC	Central nervous system infections and inflammations	Nerv	1968-2006	1	10	22501	2983643	1.138	0.263	3.561	5.025	2.682	5.025	0.102	0.87500312	0.12927234
Infliximab	Pacing threshold increased				1968-2006	1	10	22501	2983643	1.114	0.258	3.483	4.158	2.207	4.158	0.137	0.87500312	0.10795714
Infliximab	Pain	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	418	72691	22084	2910962	0.799	0.737	0.865	0.796	22.061	0.792	2.641e-6	-0.4342888	-0.2243943
Infliximab	Pain in extremity	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	235	20531	22267	2963122	0.731	0.656	0.812	0.727	24.093	0.724	9.18e-7	0.57237739	-0.3133418
Infliximab	Pain in jaw	Bone related signs and symptoms	Bone disorders (excl congenital and fractures)	Musc	1968-2006	40	1637	22462	2982016	1.559	1.196	2.004	1.63	9.433	1.631	0.002	1.58539468	0.44404459
Infliximab	Pain of skin	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	3	434	22499	2983219	0.39	0.151	0.861	0.376	3.102	0.376	0.078	-0.1056498	-0.9416085
Infliximab	Painful respiration	Respiratory signs and symptoms NEC	Respiratory disorders NEC	Resp	1968-2006	2	121	22500	2983532	0.747	0.242	1.872	0.886	0.028	0.886	0.867	0.63243733	-0.2916901
Infliximab	Palatal disorder	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	76	22501	2983577	0.588	0.136	1.835	0.673	0.154	0.673	0.695	0.33251843	-0.5310283
Infliximab	Palatal oedema	Oral soft tissue swelling and oedema	Oral soft tissue conditions	Gastr	1968-2006	1	40	22501	2983613	0.915	0.212	2.858	1.831	0.374	1.832	0.541	0.60299444	-0.0888312
Infliximab	Palliative care	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	2	22501	2983651	1.324	0.304	4.177	65.92	17.896	65.92	0.00002333	0.95711984	0.28065746
Infliximab	Pallor	Site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	84	5883	22418	2977770	1.403	1.17	1.673	1.433	10.77	1.435	0.001	0.8826925	0.3386128
Infliximab	Palmar erythema	Erythemas	Epidermal and dermal conditions	Skin	1968-2006	2	122	22500	2983531	0.854	0.277	2.141	1.097	0.017	1.097	0.897	0.62682532	-0.1578241
Infliximab	Palmar-plantar erythrodysaesthesia syndrome	Skin and subcutaneous conditions NEC	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	1	710	22501	2982943	0.126	0.029	0.394	0.09	9.19	0.09	0.002	-1.6715755	-2.0714734
Infliximab	Palpitations	Cardiac signs and symptoms NEC	Cardiac disorder signs and symptoms	Card	1968-2006	166	25840	22336	2957813	0.849	0.746	0.963	0.848	4.446	0.847	0.035	-0.25191	-0.1636961
Infliximab	Pancreatic abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	2	24	22500	2983629	1.568	0.508	3.941	4.558	4.693	4.558	0.03	1.31756088	0.44980092
Infliximab	Pancreatic atrophy	Pancreatic disorders NEC	Exocrine pancreas conditions	Gastr	1968-2006	3	55	22499	2983598	1.761	0.684	3.898	3.64	5.178	3.64	0.023	1.46893902	0.56588183
Infliximab	Pancreatic carcinoma	Pancreatic neoplasms malignant (excl islet cell and carcinoid)	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	51	912	22451	2982741	3.392	2.683	4.242	3.904	99.328	3.912	2.14e-23	2.65206451	1.22141972
Infliximab	Pancreatic carcinoma metastatic	Pancreatic neoplasms malignant (excl islet cell and carcinoid)	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	12	158	22490	2983495	2.881	1.771	4.484	3.979	24.395	3.98	7.849e-7	2.50523982	1.05813746
Infliximab	Pancreatic cyst	Pancreatic neoplasms	Malignant and unspecified neoplasms gastrointestinal NEC	Gastr	1968-2006	3	141	22499	2983512	1.104	0.429	2.44	1.475	0.431	1.475	0.512	0.93397652	0.09893995
Infliximab	Pancreatic disorder	Pancreatic disorders NEC	Exocrine pancreas conditions	Gastr	1968-2006	5	893	22497	2982760	0.502	0.238	0.958	0.501	2.444	0.501	0.118	-0.3752467	-0.6891552
Infliximab	Pancreatic duct obstruction	Pancreatic disorders NEC	Exocrine pancreas conditions	Gastr	1968-2006	1	21	22501	2983632	1.018	0.236	3.182	2.66	1.019	2.66	0.313	0.76921993	0.01783992
Infliximab	Pancreatic enzymes abnormal	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	1	16	22501	2983637	1.088	0.252	3.402	3.656	1.803	3.656	0.179	0.81634411	0.08434115
Infliximab	Pancreatic enzymes increased	Digestive enzymes	Gastrointestinal investigations	Inv	1968-2006	1	167	22501	2983486	0.452	0.104	1.41	0.444	0.708	0.444	0.4	-0.1856664	-0.7940731
Infliximab	Pancreatic haemorrhage	Pancreatic disorders NEC	Exocrine pancreas conditions	Gastr	1968-2006	1	35	22501	2983618	0.887	0.205	2.769	1.665	0.268	1.665	0.605	0.64491541	-0.1199103
Infliximab	Pancreatic neoplasm	Gastrointestinal neoplasms malignancy unspecified NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	63	22501	2983590	0.671	0.155	2.093	0.863	0.021	0.863	0.885	0.42444935	-0.3989861
Infliximab	Pancreatic pseudocyst	Pancreatic disorders NEC	Exocrine pancreas conditions	Gastr	1968-2006	3	210	22499	2983443	0.884	0.344	1.955	1.053	0.008	1.053	0.93	0.61367424	-0.1232982
Infliximab	Pancreatitis	Acute and chronic pancreatitis	Exocrine pancreas conditions	Gastr	1968-2006	77	11672	22425	2971981	0.758	0.626	0.91	0.757	5.936	0.756	0.015	-0.2059312	-0.2770719
Infliximab	Pancreatitis acute	Acute and chronic pancreatitis	Exocrine pancreas conditions	Gastr	1968-2006	21	2394	22481	2981259	0.578	0.4	0.813	0.576	6.462	0.576	0.011	0.19367069	-0.5481814
Infliximab	Pancreatitis chronic	Acute and chronic pancreatitis	Exocrine pancreas conditions	Gastr	1968-2006	2	188	22500	2983465	0.615	0.199	1.542	0.669	0.322	0.669	0.57	0.297709	-0.486133
Infliximab	Pancreatitis haemorrhagic	Acute and chronic pancreatitis	Exocrine pancreas conditions	Gastr	1968-2006	1	415	22501	2983238	0.359	0.083	1.121	0.315	1.463	0.315	0.226	-1.0515422	-1.0244329
Infliximab	Pancreatitis necrotising	Acute and chronic pancreatitis	Exocrine pancreas conditions	Gastr	1968-2006	1	441	22501	2983212	0.236	0.054	0.737	0.185	3.572	0.185	0.059	-1.1182399	-1.4439235
Infliximab	Pancytopenia	Marrow depression and hypoplastic anaemias	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	123	11322	22379	2972331	1.1	0.946	1.272	1.109	1.297	1.11	0.255	0.50042222	0.09531018
Infliximab	Panic attack	Panic symptoms	Anxiety disorders and symptoms	Psych	1968-2006	24	3354	22478	2980299	0.416	0.295	0.573	0.41	20.301	0.409	6.617e-6	-0.0847936	-0.87707
Infliximab	Panic disorder	Panic disorders	Anxiety disorders and symptoms	Psych	1968-2006	1	554	22501	2983099	0.16	0.037	0.499	0.116	6.628	0.116	0.01	-1.3768961	-1.8325815
Infliximab	Panic reaction	Panic symptoms	Anxiety disorders and symptoms	Psych	1968-2006	1	677	22501	2982976	0.114	0.026	0.357	0.082	10.475	0.082	0.001	-1.6140598	-2.1715568
Infliximab	Panniculitis	Panniculitides	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	10	164	22492	2983489	2.696	1.582	4.357	3.791	19.092	3.792	0.00001246	2.24534526	0.99176919
Infliximab	Panniculitis lobular	Panniculitides	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	4	9	22498	2983644	3.662	1.483	10.395	25.241	58.33	25.241	2.217e-14	2.17711219	1.29800945
Infliximab	Papillary muscle disorder	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	1	11	22501	2983642	1.208	0.279	3.785	7.437	4.778	7.437	0.029	0.86505951	0.1889661
Infliximab	Papillary thyroid cancer	Thyroid neoplasms malignant	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	15	115	22487	2983538	4.839	3.109	7.335	8.244	79.401	8.249	5.07e-19	3.00864467	1.57670809
Infliximab	Papillary tumour of renal pelvis	Renal neoplasms benign	Renal and urinary tract neoplasms benign	Neopl	1968-2006	1	0	22501	2983653	1.355	0.31	4.295	1080.439	60.862	1088.06	6.122e-15	0.97840063	0.30380145
Infliximab	Papillitis	Inflammations	General system disorders NEC	Genrl	1968-2006	2	54	22500	2983599	1.378	0.446	3.458	2.965	2.367	2.965	0.124	1.06904131	0.32063317
Infliximab	Papilloedema	Optic disc abnormalities NEC	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	14	1550	22488	2982103	0.919	0.586	1.387	0.953	0.031	0.953	0.86	0.2277478	-0.0844692
Infliximab	Papilloma	Neoplasms benign site unspecified NEC	Miscellaneous and site unspecified neoplasms benign	Neopl	1968-2006	5	34	22497	2983619	3.126	1.471	6.072	9.05	28.582	9.051	8.98e-8	2.20457991	1.13975423
Infliximab	Papilloma viral infection	Papilloma viral infections	Viral infectious disorders	Infec	1968-2006	2	57	22500	2983596	1.175	0.381	2.947	1.993	0.948	1.993	0.33	1.04639056	0.16126815
Infliximab	Paradoxical drug reaction	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	4	232	22498	2983421	0.93	0.406	1.889	1.072	0.02	1.072	0.889	0.8428972	-0.0725707
Infliximab	Paraesthesia	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	257	41592	22245	2942061	0.96	0.866	1.062	0.961	0.397	0.961	0.529	-0.3156453	-0.040822
Infliximab	Paraesthesia oral	Oral soft tissue pain and paraesthesia	Oral soft tissue conditions	Gastr	1968-2006	11	2819	22491	2980834	0.673	0.405	1.065	0.683	1.587	0.682	0.208	-0.89865	-0.3960099
Infliximab	Paraganglion neoplasm benign	Endocrine neoplasms benign NEC	Endocrine neoplasms benign	Neopl	1968-2006	1	0	22501	2983653	1.36	0.311	4.311	1082.489	65.988	1090.101	4.537e-16	0.97840063	0.3074847
Infliximab	Parakeratosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	4	23	22498	2983630	2.917	1.26	6.066	10.959	27.883	10.962	1.289e-7	2.04551465	1.07055569
Infliximab	Paralysis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	54	5048	22448	2978605	1.473	1.173	1.83	1.52	9.366	1.521	0.002	0.47566244	0.38730114
Infliximab	Paralysis flaccid	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	636	22501	2983017	0.459	0.106	1.433	0.454	0.665	0.454	0.415	-1.5392529	-0.7787051
Infliximab	Paralytic gait	Motor neurone diseases	Neuromuscular disorders	Nerv	1968-2006	1	2	22501	2983651	1.318	0.303	4.158	21.142	16.435	21.142	0.00005035	0.95711984	0.27611544
Infliximab	Paranasal sinus hypersecretion	Paranasal sinus disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	100	22501	2983553	0.489	0.113	1.527	0.495	0.505	0.495	0.477	0.1768059	-0.7153928
Infliximab	Paraneoplastic cerebellar degeneration	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	1	0	22501	2983653	1.344	0.308	4.254	1075.473	51.196	1083.041	8.358e-13	0.97840063	0.29565024
Infliximab	Paraneoplastic syndrome	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	2	144	22500	2983509	0.621	0.201	1.556	0.676	0.303	0.676	0.582	0.50858084	-0.4764242
Infliximab	Paranoia	Behaviour and socialisation disturbances	Personality disorders and disturbances in behaviour	Psych	1968-2006	11	5190	22491	2978463	0.244	0.147	0.387	0.234	27.278	0.234	1.762e-7	-1.7478283	-1.4105871
Infliximab	Paraoesophageal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	0	22501	2983653	1.347	0.308	4.263	1076.667	53.232	1084.286	2.964e-13	0.97840063	0.2978799
Infliximab	Paraparesis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	7	252	22495	2983401	1.502	0.796	2.632	1.828	2.557	1.828	0.11	1.43386247	0.40679755
Infliximab	Parapharyngeal abscess	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	8	22501	2983645	1.187	0.274	3.717	6.681	4.009	6.681	0.045	0.89509832	0.17142912
Infliximab	Paraplegia	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	8	847	22494	2982806	1.119	0.618	1.9	1.239	0.364	1.239	0.546	0.27116296	0.11243543
Infliximab	Paraproteinaemia	Plasma cell neoplasms NEC	Plasma cell neoplasms	Neopl	1968-2006	2	30	22500	2983623	1.471	0.477	3.694	3.548	3.36	3.549	0.067	1.26431441	0.38594244
Infliximab	Parapsoriasis	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	9	39	22493	2983614	5.255	2.84	10.53	15.42	81.216	15.424	2.023e-19	2.86820803	1.65918
Infliximab	Parathyroid tumour benign	Endocrine neoplasms benign NEC	Endocrine neoplasms benign	Neopl	1968-2006	2	98	22500	2983555	0.972	0.315	2.436	1.372	0.192	1.372	0.661	0.76793196	-0.0283995
Infliximab	Paresis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	11	634	22491	2983019	1.186	0.714	1.877	1.29	0.695	1.29	0.404	1.03080954	0.1705863
Infliximab	Paresis cranial nerve	Cranial nerve disorders NEC	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	12	22501	2983641	1.165	0.269	3.646	5.781	3.301	5.781	0.069	0.85518395	0.15272109
Infliximab	Parkinsons disease	Parkinsons disease and parkinsonism	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	13	1202	22489	2982451	0.748	0.469	1.145	0.764	0.935	0.764	0.334	0.4604155	-0.2903523
Infliximab	Parkinsonian gait	Parkinsons disease and parkinsonism	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	212	22501	2983441	0.47	0.109	1.468	0.471	0.6	0.471	0.438	-0.3863264	-0.7550226
Infliximab	Parkinsonism	Parkinsons disease and parkinsonism	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	3	865	22499	2982788	0.251	0.098	0.556	0.229	7.708	0.229	0.005	-0.9176182	-1.3823023
Infliximab	Paronychia	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	4	135	22498	2983518	1.402	0.612	2.848	1.941	1.746	1.942	0.186	1.28212974	0.33789979
Infliximab	Parophthalmia	Orbital infections, inflammations and irritations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	28	22501	2983625	1.049	0.243	3.279	3.042	1.307	3.042	0.253	0.70572945	0.04783733
Infliximab	Parosmia	Olfactory nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	2	3096	22500	2980557	0.174	0.056	0.437	0.148	9.802	0.148	0.002	-3.0236819	-1.7487
Infliximab	Parotid gland enlargement	Salivary gland enlargements	Salivary gland conditions	Gastr	1968-2006	4	572	22498	2983081	1.25	0.546	2.54	1.623	0.931	1.623	0.335	-0.0983171	0.22314355
Infliximab	Parotitis	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	8	165	22494	2983488	2.139	1.181	3.633	2.92	9.423	2.921	0.002	1.96053645	0.76033843
Infliximab	Paroxysmal nocturnal haemoglobinuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	2	23	22500	2983630	1.802	0.582	4.55	7.83	10.193	7.83	0.001	1.32662952	0.58889716
Infliximab	Partial seizures	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	2	331	22500	2983322	0.397	0.128	0.994	0.379	2.024	0.379	0.155	-0.2303413	-0.923819
Infliximab	Patella fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	3	135	22499	2983518	1.027	0.399	2.271	1.316	0.217	1.316	0.641	0.96550405	0.02664193
Infliximab	Pathogen resistance	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	15	701	22487	2982952	1.48	0.958	2.204	1.629	3.473	1.629	0.062	1.31991225	0.39204209
Infliximab	Pathological fracture	Pathological fractures and complications	Fractures	Musc	1968-2006	11	1518	22491	2982135	1.426	0.858	2.257	1.608	2.409	1.608	0.121	-0.0641092	0.35487332
Infliximab	Peak expiratory flow rate decreased	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	119	22501	2983534	0.577	0.134	1.802	0.653	0.18	0.653	0.671	0.06444279	-0.549913
Infliximab	Pectus excavatum	Musculoskeletal and connective tissue disorders of trunk congenital (excl spine)	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	1	19	22501	2983634	1.055	0.244	3.297	3.199	1.374	3.199	0.241	0.78788532	0.05354077
Infliximab	Pelvi-ureteric obstruction	Renal obstructive disorders	Renal disorders (excl nephropathies)	Renal	1968-2006	1	32	22501	2983621	0.946	0.219	2.954	2.076	0.522	2.076	0.47	0.67066536	-0.0555127
Infliximab	Pelvic abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	11	97	22491	2983556	3.905	2.343	6.228	6.534	46.249	6.538	1.042e-11	2.71934891	1.36225778
Infliximab	Pelvic fluid collection	Pelvis and broad ligament disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	26	22501	2983627	0.945	0.219	2.951	2.026	0.518	2.026	0.472	0.72358631	-0.0565704
Infliximab	Pelvic fracture	Pelvic fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	17	494	22485	2983159	1.699	1.13	2.476	1.905	6.827	1.906	0.009	1.88831897	0.53003984
Infliximab	Pelvic inflammatory disease	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	2	148	22500	2983505	0.773	0.25	1.937	0.935	0.009	0.935	0.925	0.48808539	-0.2574762
Infliximab	Pelvic inflammatory disease mycoplasmal	Mycoplasma infections	Mycoplasmal infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.346	0.308	4.26	1076.268	52.534	1083.85	4.229e-13	0.97840063	0.29713723
Infliximab	Pelvic mass	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	6	172	22496	2983481	1.747	0.882	3.181	2.381	4.499	2.382	0.034	1.57462552	0.55790003
Infliximab	Pelvic neoplasm	Neoplasms unspecified malignancy and site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	3	20	22499	2983633	2.225	0.861	4.954	7.207	13.755	7.208	0.0002082	1.75997716	0.79975692
Infliximab	Pelvic pain	Reproductive tract signs and symptoms NEC	Reproductive tract disorders NEC	Repro	1968-2006	5	4585	22497	2979068	0.415	0.197	0.793	0.405	4.297	0.405	0.038	-2.5720417	-0.8794768
Infliximab	Pelvic peritoneal adhesions	Pelvis and broad ligament disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	63	22501	2983590	0.708	0.164	2.208	0.965	0.001	0.965	0.972	0.42444935	-0.3453112
Infliximab	Pelvic venous thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	4	118	22498	2983535	1.395	0.609	2.834	1.916	1.707	1.916	0.191	1.37503731	0.33289442
Infliximab	Pemphigoid	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	5	530	22497	2983123	0.696	0.33	1.33	0.731	0.483	0.731	0.487	0.25060072	-0.3624056
Infliximab	Pemphigus	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	5	234	22497	2983419	1.147	0.544	2.19	1.368	0.479	1.368	0.489	1.09426741	0.13714984
Infliximab	Penile blister	Penile disorders NEC (excl erection and ejaculation)	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	6	22501	2983647	1.301	0.299	4.097	16.376	12.728	16.394	0.0003603	0.91547736	0.2631332
Infliximab	Penile haemorrhage	Penile disorders NEC (excl erection and ejaculation)	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	67	22501	2983586	0.774	0.179	2.415	1.175	0.026	1.175	0.872	0.39553403	-0.2561834
Infliximab	Penile malignant neoplasm	Penile neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	2	22501	2983651	1.374	0.313	4.37	71.013	48.37	71.013	3.529e-12	0.95711984	0.31772619
Infliximab	Penile pain	Penile disorders NEC (excl erection and ejaculation)	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	260	22501	2983393	0.431	0.1	1.347	0.411	0.834	0.411	0.361	-0.5734713	-0.8416472
Infliximab	Penis carcinoma	Penile neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	2	10	22500	2983643	1.945	0.625	4.946	14.358	16.933	14.366	0.00003873	1.45002205	0.66526198
Infliximab	Penis carcinoma metastatic	Penile neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	1	22501	2983652	1.352	0.309	4.282	87.428	28.966	87.428	7.368e-8	0.967721	0.30158498
Infliximab	Penis disorder	Penile disorders NEC (excl erection and ejaculation)	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	1469	22501	2982184	0.225	0.052	0.703	0.175	3.869	0.175	0.049	-2.5969206	-1.4916549
Infliximab	Peptic ulcer	Peptic ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	8	1597	22494	2982056	0.82	0.453	1.392	0.861	0.174	0.861	0.677	-0.5436699	-0.1984509
Infliximab	Peptic ulcer haemorrhage	Peptic ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	4	612	22498	2983041	1.347	0.588	2.737	1.824	1.427	1.824	0.232	-0.1774519	0.2978799
Infliximab	Peptostreptococcus infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	14	22500	2983639	1.814	0.586	4.58	8.038	10.639	8.04	0.001	1.41091905	0.59553435
Infliximab	Perforated ulcer	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	100	22500	2983553	0.791	0.256	1.983	0.969	0.002	0.969	0.965	0.75563148	-0.2344573
Infliximab	Perforation bile duct	Structural and other bile duct disorders	Bile duct disorders	Hepat	1968-2006	1	10	22501	2983643	1.212	0.28	3.797	8.013	4.948	8.013	0.026	0.87500312	0.19227189
Infliximab	Performance status decreased	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	1	579	22501	2983074	0.117	0.027	0.367	0.083	10.102	0.083	0.001	-1.428358	-2.1455813
Infliximab	Perianal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	23	140	22479	2983513	7.437	4.969	11.492	12.18	187.089	12.195	1.373e-42	3.4234226	2.00646754
Infliximab	Periarthritis	Joint related disorders NEC	Joint disorders	Musc	1968-2006	1	136	22501	2983517	0.472	0.109	1.472	0.473	0.593	0.473	0.441	-0.0291742	-0.7507763
Infliximab	Pericardial disease	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	3	105	22499	2983548	1.471	0.571	3.253	2.431	2.378	2.431	0.123	1.13438467	0.38594244
Infliximab	Pericardial drainage	Cardiac therapeutic procedures NEC	Cardiac therapeutic procedures	Surg	1968-2006	1	25	22501	2983628	1.082	0.25	3.383	3.727	1.706	3.728	0.191	0.7325983	0.07881118
Infliximab	Pericardial effusion	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	117	3404	22385	2980249	2.8	2.4	3.25	3.009	145.6	3.02	1.587e-33	2.09638238	1.02961942
Infliximab	Pericardial fibrosis	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	1	14	22501	2983639	1.04	0.241	3.249	2.964	1.222	2.965	0.269	0.83563334	0.03922071
Infliximab	Pericardial haemorrhage	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	2	377	22500	2983276	0.526	0.17	1.318	0.538	0.769	0.538	0.38	-0.366012	-0.6424541
Infliximab	Pericardial rub	Pericardial disorders NEC	Pericardial disorders	Card	1968-2006	2	24	22500	2983629	1.582	0.512	3.975	4.431	4.91	4.431	0.027	1.31756088	0.45868987
Infliximab	Pericarditis	Noninfectious pericarditis	Pericardial disorders	Card	1968-2006	130	1944	22372	2981709	6.235	5.383	7.193	7.579	625.188	7.621	0	2.97510316	1.83017858
Infliximab	Pericarditis constrictive	Noninfectious pericarditis	Pericardial disorders	Card	1968-2006	7	59	22495	2983594	3.505	1.848	6.222	8.411	34.517	8.411	4.225e-9	2.40992023	1.25419052
Infliximab	Pericarditis infective	Cardiac infections	Infections - pathogen class unspecified	Infec	1968-2006	3	16	22499	2983637	2.619	1.001	5.993	13.656	29.305	13.659	6.184e-8	1.79730948	0.96279257
Infliximab	Pericarditis lupus	Noninfectious pericarditis	Pericardial disorders	Card	1968-2006	3	4	22499	2983649	2.841	1.062	6.849	33.359	42.966	33.365	5.571e-11	1.91547742	1.0441561
Infliximab	Pericarditis rheumatic	Infectious pericarditis	Pericardial disorders	Card	1968-2006	1	4	22501	2983649	1.224	0.283	3.838	9.638	5.612	9.64	0.018	0.93614837	0.20212418
Infliximab	Pericarditis tuberculous	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	5	3	22497	2983650	13.949	2.809	48.021	78.609	167.955	78.686	2.069e-38	2.49021449	2.63540782
Infliximab	Peridiverticular abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	2	13	22500	2983640	1.831	0.591	4.626	8.765	11.345	8.765	0.001	1.4205959	0.60486227
Infliximab	Perineal abscess	Muscle and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	10	22501	2983643	1.213	0.28	3.803	7.136	5.007	7.136	0.025	0.87500312	0.19309663
Infliximab	Perineal fistula	Reproductive tract disorders NEC (excl neoplasms)	Reproductive tract disorders NEC	Repro	1968-2006	5	2	22497	2983651	8.946	2.392	36.775	83.057	131.818	83.105	1.64e-30	2.50043997	2.19120651
Infliximab	Perineal pain	Reproductive tract signs and symptoms NEC	Reproductive tract disorders NEC	Repro	1968-2006	1	56	22501	2983597	0.765	0.177	2.386	1.145	0.018	1.145	0.893	0.47648884	-0.2678794
Infliximab	Perinephric abscess	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	2	17	22500	2983636	1.839	0.593	4.648	9.057	11.545	9.059	0.001	1.38227191	0.60922195
Infliximab	Periodontal disease	Dental disorders NEC	Dental and gingival conditions	Gastr	1968-2006	1	238	22501	2983415	0.479	0.111	1.494	0.478	0.553	0.478	0.457	-0.4906963	-0.7360547
Infliximab	Periodontitis	Dental and periodontal infections and inflammations	Dental and gingival conditions	Gastr	1968-2006	3	219	22499	2983434	1.074	0.417	2.373	1.405	0.338	1.406	0.561	0.57668572	0.07139
Infliximab	Periorbital disorder	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	2	14	22500	2983639	1.729	0.559	4.355	6.69	8.023	6.69	0.005	1.41091905	0.54754321
Infliximab	Periorbital oedema	Angioedemas	Angioedema and urticaria	Skin	1968-2006	10	849	22492	2982804	0.82	0.481	1.324	0.852	0.252	0.852	0.616	0.5548429	-0.1984509
Infliximab	Periostitis	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	1	10	22501	2983643	1.22	0.282	3.824	8.127	5.303	8.129	0.021	0.87500312	0.19885086
Infliximab	Peripheral T-cell lymphoma unspecified	Peripheral T-cell lymphomas NEC	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	2	26	22500	2983627	1.633	0.529	4.106	4.871	5.811	4.871	0.016	1.29959284	0.49041881
Infliximab	Peripheral artery aneurysm	Peripheral aneurysms and dissections	Aneurysms and artery dissections	Vasc	1968-2006	1	52	22501	2983601	0.848	0.196	2.646	1.486	0.151	1.486	0.698	0.50709068	-0.1648746
Infliximab	Peripheral circulatory failure	Circulatory collapse and shock	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	1	104	22501	2983549	0.614	0.142	1.918	0.73	0.097	0.73	0.756	0.15241245	-0.4877604
Infliximab	Peripheral coldness	Body temperature perception	Body temperature conditions	Genrl	1968-2006	20	1499	22482	2982154	0.868	0.596	1.231	0.887	0.282	0.887	0.595	0.75195815	-0.1415636
Infliximab	Peripheral embolism	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	5	342	22497	2983311	1.256	0.596	2.399	1.544	0.938	1.544	0.333	0.72700222	0.22793207
Infliximab	Peripheral ischaemia	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	22	799	22480	2982854	1.975	1.38	2.758	2.187	13.664	2.189	0.0002186	1.67531299	0.6805684
Infliximab	Peripheral motor neuropathy	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	8	157	22494	2983496	2.406	1.328	4.087	3.468	13.083	3.469	0.0002979	1.99868441	0.87796562
Infliximab	Peripheral nerve injury	Peripheral nerve injuries	Injuries NEC	Inj&P	1968-2006	4	213	22498	2983440	1.605	0.7	3.261	2.411	3.173	2.412	0.075	0.91904613	0.47312376
Infliximab	Peripheral nerve operation	Peripheral nerve therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	1	14	22501	2983639	1.085	0.251	3.391	3.626	1.753	3.626	0.185	0.83563334	0.08157999
Infliximab	Peripheral paralysis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	2	17	22500	2983636	1.743	0.564	4.393	6.861	8.379	6.862	0.004	1.38227191	0.55560777
Infliximab	Peripheral sensory neuropathy	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	4	494	22498	2983159	0.543	0.237	1.102	0.551	1.443	0.551	0.23	0.06971659	-0.610646
Infliximab	Peripheral vascular disorder	Peripheral vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	12	3790	22490	2979863	0.768	0.472	1.195	0.787	0.671	0.787	0.413	-1.1928762	-0.2639655
Infliximab	Perirectal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	10	94	22492	2983559	3.667	2.148	5.959	6.434	39.163	6.436	3.899e-10	2.6179058	1.29937389
Infliximab	Peritoneal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	3	25	22499	2983628	2.102	0.815	4.668	5.87	10.745	5.87	0.001	1.71463043	0.74288927
Infliximab	Peritoneal adhesions	Peritoneal and retroperitoneal fibrosis and adhesions	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	2	53	22500	2983600	1.227	0.398	3.078	2.22	1.239	2.221	0.266	1.07667128	0.20457217
Infliximab	Peritoneal carcinoma	Gastrointestinal neoplasms malignant NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	8	75	22494	2983578	2.84	1.567	4.831	4.64	20.321	4.643	6.547e-6	2.46191313	1.04380405
Infliximab	Peritoneal cyst	Peritoneal and retroperitoneal disorders	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	1	5	22501	2983648	1.256	0.29	3.943	12.267	7.615	12.267	0.006	0.92577585	0.22793207
Infliximab	Peritoneal disorder	Peritoneal and retroperitoneal disorders	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	4	141	22498	2983512	1.637	0.714	3.327	2.531	3.451	2.532	0.063	1.25071661	0.4928653
Infliximab	Peritoneal fluid analysis abnormal	Gastrointestinal histopathology procedures	Gastrointestinal investigations	Inv	1968-2006	1	38	22501	2983615	0.815	0.189	2.544	1.34	0.083	1.34	0.774	0.61961696	-0.2045672
Infliximab	Peritoneal haematoma	Peritoneal and retroperitoneal haemorrhages	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	1	10	22501	2983643	1.089	0.252	3.404	3.741	1.818	3.742	0.177	0.87500312	0.08525984
Infliximab	Peritoneal haemorrhage	Peritoneal and retroperitoneal haemorrhages	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	1	558	22501	2983095	0.266	0.061	0.831	0.214	2.864	0.214	0.091	-1.3852543	-1.324259
Infliximab	Peritoneal tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	45	24	22457	2983629	27.437	21.312	34.877	89.57	1220.774	89.724	0	4.91196415	3.31189247
Infliximab	Peritonitis	Peritoneal and retroperitoneal disorders	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	62	4350	22440	2979303	1.906	1.542	2.336	2.006	29.799	2.009	4.791e-8	0.87580482	0.64500681
Infliximab	Peritonitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	6	306	22496	2983347	1.073	0.542	1.954	1.218	0.229	1.218	0.632	1.0585004	0.07045846
Infliximab	Peritonsillar abscess	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	4	64	22498	2983589	1.968	0.859	4.003	3.564	6.88	3.564	0.009	1.71746262	0.6770178
Infliximab	Perivascular dermatitis	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	2	26	22500	2983627	1.623	0.525	4.081	4.855	5.62	4.855	0.018	1.29959284	0.48427629
Infliximab	Peroneal nerve palsy	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	28	783	22474	2982870	3.276	2.384	4.414	3.917	56.188	3.921	6.586e-14	2.02493222	1.18662317
Infliximab	Persecutory delusion	Delusional symptoms	Disturbances in thinking and perception	Psych	1968-2006	1	313	22501	2983340	0.263	0.061	0.822	0.209	2.924	0.209	0.087	-0.7553181	-1.3356012
Infliximab	Personality change	Behaviour and socialisation disturbances	Personality disorders and disturbances in behaviour	Psych	1968-2006	3	1307	22499	2982346	0.156	0.06	0.344	0.137	16.201	0.137	0.00005698	-1.4451986	-1.8578993
Infliximab	Petechiae	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	19	4094	22483	2979559	0.658	0.447	0.941	0.661	3.247	0.661	0.072	-0.6812598	-0.4185503
Infliximab	Petit mal epilepsy	Absence seizures	Seizures (incl subtypes)	Nerv	1968-2006	7	819	22495	2982834	0.527	0.28	0.924	0.53	2.916	0.529	0.088	0.14420551	-0.6405547
Infliximab	Phaeochromocytoma	Islet cell neoplasms and APUDoma NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	2	129	22500	2983524	0.825	0.267	2.069	1.037	0.003	1.037	0.959	0.58814077	-0.1923719
Infliximab	Phagocytosis	Cell metabolism disorders NEC	Metabolism disorders NEC	Metab	1968-2006	2	2	22500	2983651	2.163	0.681	5.695	51.764	38.679	51.764	4.995e-10	1.53155852	0.77149615
Infliximab	Pharmaceutical product complaint	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	10	21638	22492	2962015	0.023	0.014	0.038	0.022	450.225	0.021	0	-3.911007	-3.7722611
Infliximab	Pharyngeal cancer stage unspecified	Pharyngeal neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	13	22501	2983640	1.113	0.257	3.479	3.958	2.179	3.958	0.14	0.84537553	0.10705907
Infliximab	Pharyngeal candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	1	17	22501	2983636	1.087	0.251	3.397	3.639	1.77	3.639	0.183	0.80679534	0.08342161
Infliximab	Pharyngeal cyst	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	5	22501	2983648	1.26	0.291	3.956	12.816	7.996	12.816	0.005	0.92577585	0.23111172
Infliximab	Pharyngeal erythema	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	3	167	22499	2983486	0.864	0.336	1.909	1.018	0.001	1.018	0.976	0.80479765	-0.1461825
Infliximab	Pharyngeal haemorrhage	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	2	129	22500	2983524	0.788	0.255	1.976	0.964	0.003	0.964	0.959	0.58814077	-0.2382572
Infliximab	Pharyngeal lesion	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	10	22501	2983643	1.185	0.274	3.71	6.574	3.906	6.575	0.048	0.87500312	0.16974277
Infliximab	Pharyngeal mass	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	13	22501	2983640	1.02	0.236	3.185	2.79	1.032	2.79	0.31	0.84537553	0.01980263
Infliximab	Pharyngeal neoplasm	Pharyngeal neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	10	22501	2983643	1.135	0.262	3.551	4.659	2.613	4.659	0.106	0.87500312	0.12663265
Infliximab	Pharyngeal oedema	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	28	2083	22474	2981570	1.016	0.74	1.369	1.041	0.044	1.041	0.834	0.77561724	0.01587335
Infliximab	Pharyngeal ulceration	Pharyngeal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	2	126	22500	2983527	0.822	0.266	2.06	1.03	0.002	1.03	0.967	0.60459304	-0.1960149
Infliximab	Pharyngitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	56	12807	22446	2970846	1.739	1.391	2.154	1.82	19.799	1.822	8.602e-6	-0.7882781	0.55331024
Infliximab	Pharyngitis streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	7	329	22495	2983324	1.088	0.577	1.906	1.218	0.262	1.218	0.609	1.17545029	0.08434115
Infliximab	Pharyngoesophageal diverticulum	Diverticula	Diverticular disorders	Gastr	1968-2006	1	9	22501	2983644	1.245	0.287	3.907	9.87	6.756	9.87	0.009	0.88501574	0.21913553
Infliximab	Pharyngolaryngeal pain	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	163	5996	22339	2977657	1.675	1.47	1.901	1.718	47.193	1.724	6.432e-12	1.78609291	0.51581317
Infliximab	Pharynx discomfort				1968-2006	2	95	22500	2983558	0.865	0.28	2.168	1.121	0.025	1.121	0.874	0.78658155	-0.1450258
Infliximab	Phimosis	Penile disorders NEC (excl erection and ejaculation)	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	2	71	22500	2983582	1.224	0.397	3.07	2.181	1.211	2.182	0.271	0.94514885	0.20212418
Infliximab	Phlebitis	Phlebitis NEC	Vascular inflammations	Vasc	1968-2006	33	6335	22469	2977318	1.649	1.231	2.171	1.752	10.146	1.754	0.001	-0.5312978	0.50016904
Infliximab	Phlebitis superficial	Phlebitis NEC	Vascular inflammations	Vasc	1968-2006	6	96	22496	2983557	2.386	1.204	4.35	3.987	12.131	3.988	0.000496	1.97802475	0.86961832
Infliximab	Phlebolith	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	13	22501	2983640	1.1	0.254	3.439	3.953	1.977	3.953	0.16	0.84537553	0.09531018
Infliximab	Phosphenes	Visual disorders NEC	Vision disorders	Eye	1968-2006	1	19	22501	2983634	1.043	0.241	3.258	3.038	1.246	3.038	0.264	0.78788532	0.04210118
Infliximab	Phosphorus metabolism disorder	Phosphorus metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	1	24	22501	2983629	1.21	0.279	3.791	6.83	4.809	6.83	0.028	0.74166694	0.19062036
Infliximab	Photodermatosis	Photosensitivity conditions	Epidermal and dermal conditions	Skin	1968-2006	2	56	22500	2983597	1.105	0.358	2.772	1.758	0.622	1.758	0.43	1.05390137	0.09984533
Infliximab	Photophobia	Ocular sensation disorders	Ocular sensory symptoms NEC	Eye	1968-2006	19	3118	22483	2980535	0.766	0.521	1.095	0.777	1.199	0.777	0.274	-0.304034	-0.2665731
Infliximab	Photopsia	Visual disorders NEC	Vision disorders	Eye	1968-2006	6	857	22496	2982796	0.489	0.247	0.891	0.488	3.203	0.488	0.073	-0.1030395	-0.7153928
Infliximab	Photosensitivity reaction	Photosensitivity conditions	Epidermal and dermal conditions	Skin	1968-2006	40	7007	22462	2976646	1.111	0.852	1.429	1.136	0.633	1.137	0.426	-0.404844	0.10526051
Infliximab	Physical assault	Criminal activity	Legal issues	SocCi	1968-2006	1	392	22501	2983261	0.215	0.049	0.671	0.167	4.197	0.167	0.041	-0.9898561	-1.5371173
Infliximab	Physical examination abnormal	Physical examination procedures	Physical examination topics	Inv	1968-2006	2	110	22500	2983543	0.778	0.252	1.95	0.944	0.006	0.944	0.936	0.69565445	-0.2510288
Infliximab	Physical testicle examination abnormal	Physical examination procedures	Physical examination topics	Inv	1968-2006	1	2	22501	2983651	1.328	0.305	4.195	36.703	19.075	36.703	0.00001257	0.95711984	0.28367405
Infliximab	Pickwickian syndrome	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	1	25	22501	2983628	1.019	0.236	3.183	2.702	1.019	2.702	0.313	0.7325983	0.01882175
Infliximab	Pigmentation disorder	Pigmentation changes NEC	Pigmentation disorders	Skin	1968-2006	4	554	22498	2983099	0.518	0.226	1.052	0.521	1.734	0.52	0.188	-0.06124	-0.65778
Infliximab	Pigmentation lip	Hyperpigmentation disorders	Pigmentation disorders	Skin	1968-2006	1	7	22501	2983646	1.22	0.282	3.825	7.326	5.383	7.326	0.02	0.90525186	0.19885086
Infliximab	Pilonidal cyst	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	3	32	22499	2983621	2.173	0.842	4.833	6.774	12.346	6.776	0.0004419	1.65344797	0.7761087
Infliximab	Pitting oedema	Oedema NEC	General system disorders NEC	Genrl	1968-2006	9	561	22493	2983092	0.77	0.439	1.273	0.798	0.452	0.797	0.501	0.91393834	-0.2613648
Infliximab	Pituitary haemorrhage	Hypothalamic and pituitary disorders NEC	Hypothalamus and pituitary gland disorders	Endo	1968-2006	1	33	22501	2983620	0.886	0.205	2.766	1.687	0.264	1.687	0.607	0.66203088	-0.1210383
Infliximab	Pituitary tumour	Endocrine neoplasms malignant and unspecified NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	3	197	22499	2983456	0.887	0.345	1.96	1.057	0.009	1.057	0.925	0.66883365	-0.1199103
Infliximab	Pituitary tumour benign	Endocrine neoplasms benign NEC	Endocrine neoplasms benign	Neopl	1968-2006	5	296	22497	2983357	0.903	0.428	1.725	1.004	0	1.004	0.993	0.87217439	-0.1020327
Infliximab	Pituitary-dependent Cushings syndrome	Anterior pituitary hyperfunction	Hypothalamus and pituitary gland disorders	Endo	1968-2006	2	35	22500	2983618	1.373	0.445	3.446	2.856	2.335	2.856	0.126	1.22139582	0.31699813
Infliximab	Pityriasis lichenoides et varioliformis acuta	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	1	8	22501	2983645	1.192	0.275	3.732	6.415	4.151	6.415	0.042	0.89509832	0.17563257
Infliximab	Pityriasis rosea	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	2	60	22500	2983593	1.299	0.421	3.258	2.488	1.714	2.488	0.19	1.0240899	0.26159474
Infliximab	Pityriasis rubra pilaris	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	1	22	22501	2983631	1.023	0.237	3.196	2.829	1.055	2.829	0.304	0.75997701	0.02273949
Infliximab	Placenta praevia	Placental abnormalities (excl neoplasms)	Placental, amniotic and cavity disorders (excl haemorrhages)	Preg	1968-2006	5	139	22497	2983514	1.405	0.666	2.684	1.82	1.762	1.82	0.184	1.51893953	0.3400373
Infliximab	Placental disorder	Placental abnormalities (excl neoplasms)	Placental, amniotic and cavity disorders (excl haemorrhages)	Preg	1968-2006	2	635	22500	2983018	0.323	0.105	0.81	0.298	3.337	0.298	0.068	-0.95429	-1.130103
Infliximab	Placental insufficiency	Placental abnormalities (excl neoplasms)	Placental, amniotic and cavity disorders (excl haemorrhages)	Preg	1968-2006	2	127	22500	2983526	0.771	0.25	1.932	0.931	0.01	0.931	0.921	0.59908808	-0.2600669
Infliximab	Plantar erythema	Erythemas	Epidermal and dermal conditions	Skin	1968-2006	1	14	22501	2983639	1.065	0.246	3.329	3.425	1.497	3.425	0.221	0.83563334	0.0629748
Infliximab	Plantar fasciitis	Ligament disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	4	178	22498	2983475	1.146	0.5	2.328	1.437	0.504	1.437	0.478	1.07079396	0.13627762
Infliximab	Plasmacytoma	Multiple myelomas	Plasma cell neoplasms	Neopl	1968-2006	6	122	22496	2983531	2.212	1.116	4.031	3.448	9.687	3.449	0.002	1.82698641	0.79389708
Infliximab	Plasmacytosis	Leukocytoses NEC	White blood cell disorders	Blood	1968-2006	3	79	22499	2983574	1.775	0.689	3.929	3.553	5.334	3.554	0.021	1.29866388	0.57380042
Infliximab	Plasminogen increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	6	22501	2983647	1.251	0.289	3.929	11.677	7.268	11.677	0.007	0.91547736	0.22394323
Infliximab	Platelet aggregation abnormal	Platelet analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	49	22501	2983604	0.839	0.194	2.619	1.443	0.131	1.443	0.717	0.53047566	-0.1755446
Infliximab	Platelet count	Platelet analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	21	318	22481	2983335	2.121	1.469	2.982	2.422	16.384	2.432	0.00005171	2.62569802	0.75188768
Infliximab	Platelet count abnormal	Platelet analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	12	388	22490	2983265	1.336	0.822	2.078	1.475	1.758	1.476	0.185	1.69153296	0.28968008
Infliximab	Platelet count decreased	Platelet analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	98	10774	22404	2972879	0.602	0.509	0.709	0.598	26.385	0.596	2.798e-7	0.24907166	-0.5074978
Infliximab	Platelet count increased	Platelet analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	45	1283	22457	2982370	1.706	1.329	2.163	1.8	15.194	1.802	0.00009703	2.06049556	0.53415145
Infliximab	Platelet disorder	Platelet disorders NEC	Platelet disorders	Blood	1968-2006	2	537	22500	2983116	0.5	0.162	1.255	0.508	0.947	0.508	0.331	-0.7580079	-0.6931472
Infliximab	Platelet toxicity	Platelet disorders NEC	Platelet disorders	Blood	1968-2006	1	2	22501	2983651	1.34	0.307	4.237	46.829	23.031	46.829	1.594e-6	0.95711984	0.29266961
Infliximab	Platelet transfusion	Blood and blood product treatment	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	1	22	22501	2983631	1.12	0.259	3.501	4.521	2.307	4.521	0.129	0.75997701	0.11332869
Infliximab	Platybasia	Musculoskeletal and connective tissue disorders of face, neck and jaw congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	1	2	22501	2983651	1.337	0.307	4.227	47.306	22.052	47.306	2.654e-6	0.95711984	0.2904283
Infliximab	Pleural adhesion	Pleural conditions NEC	Pleural disorders	Resp	1968-2006	3	92	22499	2983561	1.399	0.543	3.093	2.203	1.874	2.203	0.171	1.21418759	0.3357577
Infliximab	Pleural calcification	Pleural conditions NEC	Pleural disorders	Resp	1968-2006	1	19	22501	2983634	1.136	0.263	3.554	4.421	2.611	4.421	0.106	0.78788532	0.12751332
Infliximab	Pleural disorder	Pleural conditions NEC	Pleural disorders	Resp	1968-2006	12	610	22490	2983043	2.837	1.744	4.415	3.821	23.456	3.823	1.278e-6	1.18955817	1.04274716
Infliximab	Pleural effusion	Pneumothorax and pleural effusions NEC	Pleural disorders	Resp	1968-2006	391	10223	22111	2973430	2.965	2.726	3.219	3.137	532.742	3.183	0	2.26891377	1.08687703
Infliximab	Pleural fibrosis	Pleural conditions NEC	Pleural disorders	Resp	1968-2006	21	268	22481	2983385	4.135	2.861	5.829	5.622	71.191	5.629	3.242e-17	2.78705046	1.41948733
Infliximab	Pleural infection	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	39	152	22463	2983501	7.083	5.328	9.422	10.666	261.986	10.731	0	4.03023324	1.95769755
Infliximab	Pleural mesothelioma	Mesotheliomas malignant and unspecified	Mesotheliomas	Neopl	1968-2006	1	27	22501	2983626	0.959	0.222	2.995	2.131	0.595	2.131	0.44	0.71463025	-0.0418642
Infliximab	Pleural neoplasm	Respiratory tract and pleural neoplasms malignancy unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	12	22501	2983641	1.19	0.275	3.726	6.582	4.079	6.582	0.043	0.85518395	0.17395331
Infliximab	Pleurisy	Pleural infections and inflammations	Pleural disorders	Resp	1968-2006	69	769	22433	2982884	5.621	4.591	6.83	6.942	301.776	6.965	0	3.2555792	1.72650958
Infliximab	Pleurisy viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	1	7	22501	2983646	1.182	0.273	3.7	6.735	3.849	6.735	0.05	0.90525186	0.16720792
Infliximab	Pleuritic pain	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	42	601	22460	2983052	3.835	2.96	4.904	4.597	105.233	4.605	1.086e-24	2.87583586	1.34416943
Infliximab	Pleuropericarditis	Noninfectious pericarditis	Pericardial disorders	Card	1968-2006	8	19	22494	2983634	8.099	3.297	22.139	26.703	120.652	26.706	4.553e-28	2.8935119	2.0917406
Infliximab	Pneumatosis	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	59	22500	2983594	1.037	0.336	2.6	1.547	0.372	1.547	0.542	1.03148523	0.03633193
Infliximab	Pneumococcal bacteraemia	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	8	22501	2983645	1.204	0.278	3.774	8.078	4.646	8.078	0.031	0.89509832	0.18564935
Infliximab	Pneumococcal infection	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	7	125	22495	2983528	2.524	1.338	4.429	3.992	14.415	3.994	0.0001466	1.99773681	0.92584494
Infliximab	Pneumococcal sepsis	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	6	47	22496	2983606	3.249	1.632	5.986	7.884	29.136	7.886	6.746e-8	2.3144463	1.17834726
Infliximab	Pneumoconiosis	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	2	42	22500	2983611	1.526	0.494	3.832	3.964	4.032	3.964	0.045	1.16337692	0.42264993
Infliximab	Pneumocystis jiroveci infection	Pneumocystis infections	Fungal infectious disorders	Infec	1968-2006	40	127	22462	2983526	15.482	11.683	20.06	24.275	574.998	24.331	0	4.17668811	2.73967806
Infliximab	Pneumocystis jiroveci pneumonia	Pneumocystis infections	Fungal infectious disorders	Infec	1968-2006	209	921	22293	2982732	10.853	9.621	12.195	14.641	1951.376	14.778	0	4.46135504	2.38444154
Infliximab	Pneumomediastinum	Mediastinal disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	5	105	22497	2983548	1.864	0.884	3.562	2.841	5.521	2.842	0.019	1.70745273	0.62272472
Infliximab	Pneumonia	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	954	31671	21548	2951982	2.822	2.675	2.976	2.965	1177.306	3.066	0	1.93525753	1.03744585
Infliximab	Pneumonia aspergillus				1968-2006	10	176	22492	2983477	2.596	1.524	4.195	3.627	17.361	3.628	0.0000309	2.19012678	0.9539718
Infliximab	Pneumonia aspiration	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	23	3282	22479	2980371	0.594	0.418	0.823	0.593	6.368	0.592	0.012	-0.1133452	-0.520876
Infliximab	Pneumonia bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	27	521	22475	2983132	2.909	2.105	3.939	3.4	42.661	3.403	6.51e-11	2.44521326	1.06780938
Infliximab	Pneumonia blastomyces	Blastomyces infections	Fungal infectious disorders	Infec	1968-2006	2	3	22500	2983650	2.218	0.692	5.941	62.229	46.557	62.229	8.897e-12	1.5211109	0.79660589
Infliximab	Pneumonia chlamydial	Chlamydial infections	Chlamydial infectious disorders	Infec	1968-2006	2	43	22500	2983610	1.391	0.451	3.491	2.947	2.494	2.947	0.114	1.15527573	0.33002291
Infliximab	Pneumonia cytomegaloviral	Cytomegaloviral infections	Viral infectious disorders	Infec	1968-2006	9	179	22493	2983474	2.177	1.243	3.6	2.935	10.385	2.936	0.001	2.04362189	0.77794778
Infliximab	Pneumonia escherichia	Escherichia infections	Bacterial infectious disorders	Infec	1968-2006	1	30	22501	2983623	0.95	0.22	2.967	2.107	0.544	2.107	0.461	0.68809089	-0.0512933
Infliximab	Pneumonia fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	18	254	22484	2983399	3.459	2.325	4.995	4.675	45.668	4.677	1.401e-11	2.63478927	1.24097953
Infliximab	Pneumonia haemophilus	Haemophilus infections	Bacterial infectious disorders	Infec	1968-2006	3	41	22499	2983612	2.279	0.882	5.083	7.852	15.161	7.854	0.0000987	1.57841455	0.82373675
Infliximab	Pneumonia herpes viral	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	2	26	22500	2983627	1.613	0.522	4.056	4.86	5.455	4.861	0.02	1.29959284	0.4780958
Infliximab	Pneumonia influenzal	Influenza viral infections	Viral infectious disorders	Infec	1968-2006	2	21	22500	2983632	1.663	0.538	4.184	5.51	6.433	5.511	0.011	1.34493959	0.5086232
Infliximab	Pneumonia klebsiella	Klebsiella infections	Bacterial infectious disorders	Infec	1968-2006	11	236	22491	2983417	2.524	1.519	3.997	3.356	16.914	3.357	0.00003912	2.06361717	0.92584494
Infliximab	Pneumonia legionella	Legionella infections	Bacterial infectious disorders	Infec	1968-2006	76	114	22426	2983539	21.797	17.973	26.237	45.934	1574.852	46.133	0	4.97955416	3.08177235
Infliximab	Pneumonia lipoid	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	2	14	22500	2983639	2.025	0.649	5.19	16.199	22.774	16.199	1.822e-6	1.41091905	0.7055697
Infliximab	Pneumonia mycoplasmal	Mycoplasma infections	Mycoplasmal infectious disorders	Infec	1968-2006	8	139	22494	2983514	2.538	1.4	4.312	3.845	15.117	3.846	0.0001011	2.08839365	0.93137637
Infliximab	Pneumonia necrotising	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	4	32	22498	2983621	2.466	1.074	5.039	6.044	15.146	6.046	0.0000995	1.96684382	0.9025974
Infliximab	Pneumonia pneumococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	20	207	22482	2983446	4.474	3.064	6.371	6.368	79.793	6.372	4.157e-19	2.94886159	1.49828286
Infliximab	Pneumonia primary atypical	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	13	228	22489	2983425	3	1.88	4.597	4.099	27.786	4.101	1.355e-7	2.30893804	1.09861229
Infliximab	Pneumonia staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	29	341	22473	2983312	4.004	2.93	5.372	5.082	84.561	5.088	3.725e-20	2.98148548	1.38729386
Infliximab	Pneumonia streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	19	194	22483	2983459	4.44	3.011	6.378	6.578	76.526	6.582	2.174e-18	2.93560711	1.49065438
Infliximab	Pneumonia viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	15	227	22487	2983426	3.216	2.081	4.796	4.346	35.088	4.348	3.151e-9	2.49773706	1.16813835
Infliximab	Pneumonitis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	158	2843	22344	2980810	3.579	3.136	4.072	3.9	313.305	3.923	0	2.74832512	1.27508343
Infliximab	Pneumonitis chemical	Chemical injuries	Chemical injury and poisoning	Inj&P	1968-2006	1	25	22501	2983628	0.993	0.23	3.101	2.499	0.813	2.499	0.367	0.7325983	-0.0070246
Infliximab	Pneumonitis cryptococcal	Cryptococcal infections	Fungal infectious disorders	Infec	1968-2006	30	36	22472	2983617	22.075	16.149	29.594	48.68	648.447	48.73	0	4.36412028	3.09444575
Infliximab	Pneumoperitoneum	Peritoneal and retroperitoneal disorders	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	3	132	22499	2983521	0.962	0.374	2.127	1.191	0.088	1.191	0.766	0.98152995	-0.0387408
Infliximab	Pneumothorax	Pneumothorax and pleural effusions NEC	Pleural disorders	Resp	1968-2006	60	1740	22442	2981913	2.679	2.159	3.294	2.922	70.835	2.928	3.885e-17	2.06370785	0.98544359
Infliximab	Pneumothorax spontaneous tension	Pneumothorax and pleural effusions NEC	Pleural disorders	Resp	1968-2006	1	4	22501	2983649	1.283	0.296	4.034	17.589	10.244	17.589	0.001	0.93614837	0.24920109
Infliximab	Pneumothorax traumatic	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	1	16	22501	2983637	1.039	0.24	3.248	3.047	1.214	3.047	0.27	0.81634411	0.03825871
Infliximab	Poisoning	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	4	619	22498	2983034	0.457	0.2	0.929	0.452	2.632	0.452	0.105	-0.1908652	-0.7830719
Infliximab	Pollakiuria	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	24	8116	22478	2975537	0.423	0.3	0.582	0.417	19.471	0.416	0.00001022	-1.3234882	-0.8603831
Infliximab	Polyarteritis nodosa	Vasculitides	Immune disorders NEC	Immun	1968-2006	6	170	22496	2983483	2.514	1.268	4.586	4.331	14.089	4.332	0.0001744	1.58391639	0.92187511
Infliximab	Polyarthritis	Arthropathies NEC	Joint disorders	Musc	1968-2006	76	455	22426	2983198	8.077	6.586	9.892	10.686	538.37	10.724	0	3.94111131	2.08902052
Infliximab	Polychondritis	Cartilage disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	5	16	22497	2983637	4.526	1.905	15.318	27.183	72.618	27.188	1.574e-17	2.36348522	1.50983855
Infliximab	Polycythaemia	Polycythaemia (excl rubra vera)	Red blood cell disorders	Blood	1968-2006	3	458	22499	2983195	0.805	0.313	1.779	0.924	0.019	0.924	0.891	-0.1651016	-0.216913
Infliximab	Polycythaemia vera	Myeloproliferative disorders (excl leukaemias)	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Neopl	1968-2006	4	58	22498	2983595	2.224	0.97	4.531	4.915	10.531	4.916	0.001	1.76105581	0.79930738
Infliximab	Polydactyly	Musculoskeletal and connective tissue disorders of limbs congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	1	136	22501	2983517	0.436	0.101	1.36	0.413	0.812	0.413	0.368	-0.0291742	-0.830113
Infliximab	Polydipsia	Fluid intake increased	Electrolyte and fluid balance conditions	Metab	1968-2006	2	980	22500	2982673	0.175	0.057	0.44	0.149	9.675	0.149	0.002	-1.4882253	-1.7429693
Infliximab	Polyhydramnios	Amniotic fluid and cavity disorders of pregnancy NEC	Placental, amniotic and cavity disorders (excl haemorrhages)	Preg	1968-2006	2	196	22500	2983457	0.57	0.185	1.43	0.602	0.517	0.602	0.472	0.26247223	-0.5621189
Infliximab	Polymorphic light eruption	Photosensitivity conditions	Epidermal and dermal conditions	Skin	1968-2006	1	7	22501	2983646	1.193	0.276	3.737	6.239	4.224	6.239	0.04	0.90525186	0.17647114
Infliximab	Polymyalgia				1968-2006	2	119	22500	2983534	0.85	0.275	2.13	1.087	0.014	1.087	0.907	0.64372726	-0.1625189
Infliximab	Polymyalgia rheumatica	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	3	341	22499	2983312	0.617	0.24	1.364	0.652	0.551	0.652	0.458	0.15107437	-0.4828863
Infliximab	Polymyositis	Muscle infections and inflammations	Muscle disorders	Musc	1968-2006	14	439	22488	2983214	1.799	1.147	2.716	2.063	7.328	2.064	0.007	1.76133951	0.58723095
Infliximab	Polyneuropathy	Acute polyneuropathies	Peripheral neuropathies	Nerv	1968-2006	37	1288	22465	2982365	2.156	1.636	2.798	2.32	26.967	2.323	2.069e-7	1.7878233	0.76825465
Infliximab	Polyp	Mucosal findings abnormal	General system disorders NEC	Genrl	1968-2006	11	510	22491	2983143	1.497	0.901	2.37	1.7	3.049	1.7	0.081	1.28113977	0.40346311
Infliximab	Polyp colorectal	Benign neoplasms gastrointestinal (excl oral cavity)	Benign neoplasms gastrointestinal	Gastr	1968-2006	3	39	22499	2983614	1.93	0.749	4.278	4.763	7.547	4.764	0.006	1.59475468	0.65752
Infliximab	Polyserositis	Inflammations	General system disorders NEC	Genrl	1968-2006	9	103	22493	2983550	3.822	2.171	6.39	7.274	42.411	7.277	7.398e-11	2.4326216	1.34077385
Infliximab	Polyuria	Urinary tract signs and symptoms NEC	Urinary tract signs and symptoms	Renal	1968-2006	9	2837	22493	2980816	0.495	0.282	0.818	0.493	4.656	0.493	0.031	-1.169461	-0.7031975
Infliximab	Poor peripheral circulation	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	501	22500	2983152	0.278	0.09	0.697	0.248	4.514	0.248	0.034	-0.6786283	-1.2801342
Infliximab	Poor quality sleep	Sleep disturbances NEC	Sleep disturbances (incl subtypes)	Nerv	1968-2006	1	148	22501	2983505	0.425	0.098	1.328	0.405	0.882	0.405	0.348	-0.0917807	-0.8556661
Infliximab	Poor venous access	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	3	53	22499	2983600	1.626	0.632	3.598	3.051	3.72	3.051	0.054	1.48407896	0.48612301
Infliximab	Porphyria	Inborn errors of porphyrin metabolism	Metabolic and nutritional disorders congenital	Cong	1968-2006	1	404	22501	2983249	0.561	0.13	1.751	0.621	0.227	0.621	0.634	-1.0223689	-0.5780344
Infliximab	Porphyria non-acute	Inborn errors of porphyrin metabolism	Metabolic and nutritional disorders congenital	Cong	1968-2006	1	117	22501	2983536	0.567	0.131	1.77	0.638	0.208	0.638	0.648	0.0758668	-0.567396
Infliximab	Portal hypertension	Hepatic vascular disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	5	486	22497	2983167	0.679	0.322	1.297	0.711	0.58	0.711	0.446	0.34883348	-0.3871342
Infliximab	Portal vein thrombosis	Hepatic vascular disorders	Hepatic and hepatobiliary disorders	Hepat	1968-2006	1	324	22501	2983329	0.268	0.062	0.836	0.216	2.829	0.216	0.093	-0.7903501	-1.3167683
Infliximab	Positron emission tomogram abnormal	Imaging procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	2	36	22500	2983617	1.461	0.473	3.667	3.481	3.222	3.481	0.073	1.2129632	0.37912113
Infliximab	Post herpetic neuralgia	Paraesthesias and dysaesthesias	Neurological disorders NEC	Nerv	1968-2006	11	76	22491	2983577	4.675	2.777	7.649	9.126	67.245	9.131	2.398e-16	2.85054919	1.54222916
Infliximab	Post procedural bile leak	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	21	22501	2983632	1.041	0.241	3.253	3.01	1.226	3.01	0.268	0.76921993	0.04018179
Infliximab	Post procedural cellulitis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	19	22500	2983634	1.728	0.559	4.353	6.492	7.961	6.494	0.005	1.36348501	0.54696467
Infliximab	Post procedural complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	137	5684	22365	2977969	1.287	1.117	1.478	1.307	9.559	1.309	0.002	1.61686841	0.25231393
Infliximab	Post procedural diarrhoea	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	65	22500	2983588	1.027	0.333	2.574	1.514	0.34	1.514	0.56	0.98767138	0.02664193
Infliximab	Post procedural discharge	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	31	22501	2983622	0.862	0.199	2.691	1.566	0.19	1.566	0.663	0.67935182	-0.1485
Infliximab	Post procedural drainage	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	13	22501	2983640	1.092	0.252	3.413	3.677	1.855	3.678	0.173	0.84537553	0.08801088
Infliximab	Post procedural fistula	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	24	22500	2983629	1.608	0.521	4.042	4.725	5.349	4.725	0.021	1.31756088	0.47499117
Infliximab	Post procedural haematoma	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	243	22499	2983410	0.684	0.266	1.513	0.743	0.26	0.743	0.61	0.48244825	-0.3797974
Infliximab	Post procedural haemorrhage	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	21	1352	22481	2982301	0.926	0.641	1.302	0.948	0.057	0.948	0.811	0.95258489	-0.076881
Infliximab	Post procedural headache	Neurological and psychiatric procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	20	22501	2983633	0.956	0.221	2.984	2.169	0.576	2.169	0.448	0.77852244	-0.0449974
Infliximab	Post procedural nausea	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	135	22499	2983518	0.966	0.375	2.135	1.199	0.094	1.199	0.759	0.96550405	-0.0345914
Infliximab	Post procedural vomiting	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	131	22500	2983522	0.708	0.23	1.775	0.82	0.078	0.82	0.78	0.57727589	-0.3453112
Infliximab	Post thrombotic syndrome	Non-site specific embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	37	22501	2983616	0.89	0.206	2.779	1.71	0.278	1.71	0.598	0.62800058	-0.1165338
Infliximab	Posterior segment of eye anomaly	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	1	2	22501	2983651	1.32	0.303	4.166	23.064	16.944	23.075	0.00003849	0.95711984	0.27763174
Infliximab	Postmenopausal haemorrhage	Menopausal effects on the genitourinary tract	Menopause and related conditions	Repro	1968-2006	7	292	22495	2983361	1.194	0.633	2.092	1.368	0.662	1.368	0.416	1.29386811	0.17730901
Infliximab	Postmenopause	Age related issues	Age related factors	SocCi	1968-2006	1	9	22501	2983644	1.158	0.268	3.624	5.684	3.145	5.684	0.076	0.88501574	0.14669438
Infliximab	Postnasal drip	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	7	344	22495	2983309	1.173	0.622	2.056	1.335	0.573	1.335	0.449	1.13008061	0.15956457
Infliximab	Postoperative abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	5	38	22497	2983615	2.75	1.301	5.283	6.368	19.119	6.37	0.00001228	2.17152423	1.01160091
Infliximab	Postoperative adhesion	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	118	22500	2983535	0.846	0.274	2.12	1.08	0.011	1.08	0.915	0.64940552	-0.1672359
Infliximab	Postoperative fever	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	90	22500	2983563	0.877	0.284	2.198	1.146	0.036	1.146	0.849	0.81821007	-0.1312483
Infliximab	Postoperative ileus	Gastrointestinal and hepatobiliary procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	52	22499	2983601	1.888	0.733	4.182	4.293	6.848	4.293	0.009	1.49170892	0.63551807
Infliximab	Postoperative infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	55	653	22447	2983000	3.51	2.801	4.355	4.055	113.403	4.066	1.761e-26	3.14093646	1.25561604
Infliximab	Postoperative thrombosis	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	81	22500	2983572	0.936	0.303	2.347	1.283	0.12	1.283	0.729	0.8769495	-0.0661398
Infliximab	Postoperative wound complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	6	195	22496	2983458	1.329	0.671	2.42	1.605	1.333	1.605	0.248	1.47187074	0.28442678
Infliximab	Postoperative wound infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	21	400	22481	2983253	2.742	1.899	3.858	3.297	31.07	3.302	2.488e-8	2.39482863	1.00868758
Infliximab	Postrenal failure	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	1	26	22501	2983627	1.002	0.232	3.13	2.561	0.878	2.561	0.349	0.72358631	0.001998
Infliximab	Posture abnormal	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	292	22501	2983361	0.279	0.064	0.872	0.226	2.603	0.226	0.107	-0.6859811	-1.2765435
Infliximab	Pouchitis	Gastrointestinal inflammatory disorders NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	7	19	22495	2983634	6.086	2.691	18.172	23.577	95.359	23.603	1.588e-22	2.73259879	1.80599105
Infliximab	Pre-eclampsia	Hypertension associated disorders of pregnancy	Maternal complications of pregnancy	Preg	1968-2006	11	503	22491	2983150	1.095	0.659	1.733	1.177	0.283	1.177	0.595	1.29665388	0.09075436
Infliximab	Precancerous cells present	Investigations NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	4	59	22498	2983594	1.898	0.828	3.86	3.332	6.065	3.332	0.014	1.7536982	0.6408007
Infliximab	Precancerous skin lesion	Skin preneoplastic conditions NEC	Cornification and dystrophic skin disorders	Skin	1968-2006	1	24	22501	2983629	1.001	0.231	3.126	2.522	0.871	2.522	0.351	0.74166694	0.0009995
Infliximab	Pregnancy	Normal pregnancy, labour and delivery	Pregnancy, labour, delivery and postpartum conditions	Preg	1968-2006	102	7396	22400	2976257	0.733	0.622	0.86	0.73	10.071	0.728	0.002	0.83603426	-0.3106096
Infliximab	Pregnancy induced hypertension	Hypertension associated disorders of pregnancy	Maternal complications of pregnancy	Preg	1968-2006	3	131	22499	2983522	0.996	0.387	2.202	1.257	0.149	1.257	0.7	0.98691172	-0.004008
Infliximab	Pregnancy of partner	Family and partner issues	Family issues	SocCi	1968-2006	1	105	22501	2983548	0.469	0.108	1.463	0.468	0.611	0.468	0.434	0.14637798	-0.7571525
Infliximab	Pregnancy on oral contraceptive	Unintended pregnancies	Pregnancy, labour, delivery and postpartum conditions	Preg	1968-2006	1	547	22501	2983106	0.122	0.028	0.382	0.088	9.624	0.088	0.002	-1.3621518	-2.1037342
Infliximab	Pregnancy test positive	Reproductive hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	150	22501	2983503	0.476	0.11	1.485	0.477	0.573	0.477	0.449	-0.1019561	-0.7423374
Infliximab	Premature baby	Gestational age and weight conditions	Neonatal and perinatal conditions	Preg	1968-2006	48	3934	22454	2979719	0.85	0.667	1.07	0.855	1.161	0.855	0.281	0.65680442	-0.1625189
Infliximab	Premature labour	Labour onset and length abnormalities	Maternal complications of labour and delivery	Preg	1968-2006	33	1173	22469	2982480	1.579	1.179	2.08	1.671	8.515	1.673	0.004	1.75019674	0.45679174
Infliximab	Premature menopause	Menopausal effects NEC	Menopause and related conditions	Repro	1968-2006	1	80	22501	2983573	0.604	0.14	1.886	0.713	0.118	0.713	0.732	0.30537124	-0.5041811
Infliximab	Premature rupture of membranes	Labour onset and length abnormalities	Maternal complications of labour and delivery	Preg	1968-2006	1	500	22501	2983153	0.147	0.034	0.46	0.105	7.476	0.105	0.006	-1.2590505	-1.9173227
Infliximab	Premature separation of placenta	Haemorrhagic complications of pregnancy	Maternal complications of pregnancy	Preg	1968-2006	3	315	22499	2983338	0.484	0.188	1.071	0.485	1.636	0.485	0.201	0.2318451	-0.7256704
Infliximab	Primary hypothyroidism	Thyroid hypofunction disorders	Thyroid gland disorders	Endo	1968-2006	1	11	22501	2983642	1.159	0.268	3.626	5.517	3.15	5.517	0.076	0.86505951	0.14755756
Infliximab	Procedural complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	22	1849	22480	2981804	0.701	0.49	0.979	0.705	2.659	0.705	0.103	0.60445588	-0.3552474
Infliximab	Procedural pain	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	5	649	22497	2983004	0.477	0.226	0.911	0.473	2.889	0.473	0.089	0.01422192	-0.7402388
Infliximab	Procedural site reaction	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	6	406	22496	2983247	1.002	0.506	1.824	1.12	0.074	1.12	0.786	0.76635493	0.001998
Infliximab	Proctalgia	Anal and rectal pains	Anal and rectal conditions NEC	Gastr	1968-2006	18	604	22484	2983049	1.876	1.262	2.706	2.101	10.007	2.102	0.002	1.73704836	0.62914185
Infliximab	Proctitis	Rectal inflammations NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	4	425	22498	2983228	0.932	0.407	1.894	1.078	0.022	1.078	0.883	0.23665288	-0.0704225
Infliximab	Proctitis ulcerative	Rectal inflammations NEC	Gastrointestinal inflammatory conditions	Gastr	1968-2006	4	82	22498	2983571	2.612	1.136	5.354	7.067	18.466	7.072	0.0000173	1.59406879	0.96011621
Infliximab	Productive cough	Coughing and associated symptoms	Respiratory disorders NEC	Resp	1968-2006	47	3251	22455	2980402	1.373	1.075	1.732	1.416	5.583	1.417	0.018	0.88960931	0.31699813
Infliximab	Progesterone decreased	Reproductive hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	20	22501	2983633	1.035	0.239	3.233	2.938	1.168	2.938	0.28	0.77852244	0.03440143
Infliximab	Progesterone receptor assay positive	Reproductive hormone analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	2	740	22500	2982913	0.173	0.056	0.434	0.147	9.932	0.146	0.002	-1.1386316	-1.7544637
Infliximab	Progressive multifocal leukoencephalopathy	Polyomavirus infections	Viral infectious disorders	Infec	1968-2006	1	243	22501	2983410	0.335	0.077	1.045	0.291	1.745	0.291	0.187	-0.5099301	-1.0936247
Infliximab	Prolapse repair	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	2	22501	2983651	1.301	0.299	4.098	30.81	12.989	30.81	0.0003133	0.95711984	0.2631332
Infliximab	Prostate cancer	Prostatic neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	72	1928	22430	2981725	3.478	2.856	4.202	3.853	141.478	3.891	1.265e-32	2.18070324	1.24645742
Infliximab	Prostate cancer stage 0	Prostatic neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	1	22501	2983652	1.335	0.306	4.219	53.559	21.403	53.559	3.721e-6	0.967721	0.28893129
Infliximab	Prostate cancer stage II	Prostatic neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	1	22501	2983652	1.37	0.312	4.351	88.367	43.19	88.541	4.967e-11	0.967721	0.31481074
Infliximab	Prostate examination abnormal	Physical examination procedures	Physical examination topics	Inv	1968-2006	3	128	22499	2983525	1.226	0.477	2.711	1.749	0.913	1.749	0.339	1.00317851	0.20375684
Infliximab	Prostate infection	Male reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	45	22501	2983608	0.791	0.183	2.469	1.242	0.046	1.242	0.831	0.56225713	-0.2344573
Infliximab	Prostatic abscess	Male reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	18	22501	2983635	1.116	0.258	3.49	4.058	2.226	4.059	0.136	0.79730935	0.10975086
Infliximab	Prostatic adenoma	Prostatic neoplasms benign	Reproductive neoplasms male benign	Neopl	1968-2006	2	58	22500	2983595	1.534	0.497	3.854	4.016	4.159	4.018	0.041	1.03891865	0.4278787
Infliximab	Prostatic disorder	Prostatic signs, symptoms and disorders NEC	Prostatic disorders (excl infections and inflammations)	Repro	1968-2006	2	1490	22500	2982163	0.418	0.135	1.047	0.403	1.739	0.403	0.187	-2.0316264	-0.8722738
Infliximab	Prostatic obstruction	Prostatic signs, symptoms and disorders NEC	Prostatic disorders (excl infections and inflammations)	Repro	1968-2006	1	13	22501	2983640	1.141	0.264	3.568	4.8	2.719	4.801	0.099	0.84537553	0.13190507
Infliximab	Prostatic operation	Prostatic therapeutic procedures	Male genital tract therapeutic procedures	Surg	1968-2006	1	106	22501	2983547	0.513	0.119	1.601	0.537	0.396	0.537	0.529	0.14036864	-0.6674794
Infliximab	Prostatic specific antigen	Cell marker procedures	Immunology and allergy investigations	Inv	1968-2006	1	8	22501	2983645	1.208	0.279	3.785	7.445	4.78	7.46	0.029	0.89509832	0.1889661
Infliximab	Prostatic specific antigen increased	Cell marker procedures	Immunology and allergy investigations	Inv	1968-2006	5	1030	22497	2982623	0.721	0.342	1.376	0.763	0.362	0.763	0.547	-0.5552113	-0.3271161
Infliximab	Prostatitis	Prostate and seminal vesicles infections and inflammations	Male reproductive tract infections and inflammations	Repro	1968-2006	10	437	22492	2983216	1.59	0.934	2.568	1.841	3.765	1.842	0.052	1.32871455	0.46373402
Infliximab	Prosthesis implantation	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	19	22501	2983634	1.039	0.24	3.247	2.947	1.211	2.947	0.271	0.78788532	0.03825871
Infliximab	Prostration	Asthenic conditions	General system disorders NEC	Genrl	1968-2006	3	135	22499	2983518	0.998	0.388	2.207	1.258	0.154	1.258	0.695	0.96550405	-0.002002
Infliximab	Protein C increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	10	22501	2983643	1.131	0.261	3.536	4.814	2.526	4.814	0.112	0.87500312	0.1231022
Infliximab	Protein S decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	49	22501	2983604	0.717	0.166	2.239	0.994	0	0.994	0.995	0.53047566	-0.3326794
Infliximab	Protein S increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	7	22501	2983646	1.149	0.266	3.596	5.394	2.94	5.394	0.086	0.90525186	0.138892
Infliximab	Protein total	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	3	33	22499	2983620	1.828	0.71	4.047	3.938	6.055	3.941	0.014	1.64491562	0.60322247
Infliximab	Protein total abnormal	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	1	65	22501	2983588	0.657	0.152	2.052	0.831	0.034	0.831	0.854	0.40991926	-0.4200713
Infliximab	Protein total decreased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	16	882	22486	2982771	1.096	0.719	1.614	1.152	0.311	1.152	0.577	1.12725823	0.09166719
Infliximab	Protein total increased	Protein analyses NEC	Protein and chemistry analyses NEC	Inv	1968-2006	6	400	22496	2983253	0.921	0.465	1.678	1.01	0.001	1.01	0.982	0.78231127	-0.0822952
Infliximab	Protein urine present	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	6	503	22496	2983150	0.62	0.313	1.13	0.634	1.238	0.634	0.266	0.53022888	-0.4780358
Infliximab	Proteinuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	37	2527	22465	2981126	1.208	0.917	1.567	1.242	1.703	1.243	0.192	0.90013024	0.1889661
Infliximab	Proteus infection	Proteus infections	Bacterial infectious disorders	Infec	1968-2006	14	153	22488	2983500	3.758	2.392	5.688	5.623	46.921	5.628	7.392e-12	2.72601967	1.3238869
Infliximab	Prothrombin level decreased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	9053	22499	2974600	0.305	0.118	0.674	0.283	5.356	0.283	0.021	-4.1192855	-1.1874435
Infliximab	Prothrombin level increased	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	1670	22500	2981983	0.507	0.164	1.271	0.516	0.896	0.516	0.344	-2.1832199	-0.6792443
Infliximab	Prothrombin time	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	68	22501	2983585	0.597	0.138	1.862	0.693	0.135	0.693	0.714	0.38839484	-0.5158382
Infliximab	Prothrombin time abnormal	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	342	22499	2983311	0.542	0.211	1.198	0.553	1.06	0.553	0.303	0.14805629	-0.6124893
Infliximab	Prothrombin time prolonged	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	19	4365	22483	2979288	0.352	0.24	0.504	0.346	23.443	0.345	1.287e-6	-0.7706395	-1.0441241
Infliximab	Prothrombin time ratio abnormal	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	21	22501	2983632	1.041	0.241	3.251	2.887	1.224	2.887	0.269	0.76921993	0.04018179
Infliximab	Prothrombin time shortened	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	5	664	22497	2982989	0.56	0.265	1.069	0.567	1.624	0.567	0.203	-0.0130035	-0.5798185
Infliximab	Prurigo	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	4	226	22498	2983427	0.908	0.396	1.845	1.041	0.006	1.041	0.938	0.86651296	-0.0965109
Infliximab	Pruritus	Pruritus NEC	Epidermal and dermal conditions	Skin	1968-2006	408	82688	22094	2900965	1.178	1.085	1.277	1.185	11.692	1.189	0.001	-0.6585149	0.16381809
Infliximab	Pruritus ani	Anal and rectal signs and symptoms	Anal and rectal conditions NEC	Gastr	1968-2006	2	126	22500	2983527	0.903	0.293	2.263	1.202	0.067	1.202	0.796	0.60459304	-0.1020327
Infliximab	Pruritus generalised	Pruritus NEC	Epidermal and dermal conditions	Skin	1968-2006	16	1534	22486	2982119	0.527	0.346	0.776	0.523	6.85	0.523	0.009	0.42027489	-0.6405547
Infliximab	Pseudarthrosis	Pathological fractures and complications	Fractures	Musc	1968-2006	2	22	22500	2983631	1.748	0.565	4.405	6.685	8.481	6.687	0.004	1.33575551	0.55847228
Infliximab	Pseudo lymphoma				1968-2006	3	1427	22499	2982226	1.348	0.524	2.98	2.051	1.557	2.051	0.212	-1.5604575	0.29862201
Infliximab	Pseudomeningocele	Site specific procedural complications NEC	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	9	22501	2983644	1.173	0.271	3.673	5.951	3.548	5.952	0.06	0.88501574	0.15956457
Infliximab	Pseudomonal sepsis	Pseudomonal infections	Bacterial infectious disorders	Infec	1968-2006	11	258	22491	2983395	2.349	1.414	3.72	3.047	14.031	3.048	0.0001799	1.98253403	0.85398971
Infliximab	Pseudomonas infection	Pseudomonal infections	Bacterial infectious disorders	Infec	1968-2006	69	1350	22433	2982303	3.17	2.592	3.845	3.492	114.268	3.501	1.139e-26	2.57904541	1.15373159
Infliximab	Pseudomyxoma peritonei	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	1	9	22501	2983644	1.165	0.269	3.646	5.788	3.337	5.788	0.068	0.88501574	0.15272109
Infliximab	Pseudopolyp	Inflammations	General system disorders NEC	Genrl	1968-2006	3	14	22499	2983639	2.551	0.979	5.789	13.626	25.878	13.629	3.636e-7	1.81634422	0.93648544
Infliximab	Pseudopolyposis	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	1	12	22501	2983641	1.126	0.26	3.523	4.246	2.434	4.246	0.119	0.85518395	0.11867153
Infliximab	Pseudoporphyria	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	3	39	22499	2983614	2.082	0.807	4.622	5.79	10.284	5.79	0.001	1.59475468	0.73332897
Infliximab	Psoas abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	23	22501	2983630	1.02	0.236	3.185	2.712	1.024	2.712	0.311	0.75079293	0.01980263
Infliximab	Psoriasis	Psoriatic conditions	Epidermal and dermal conditions	Skin	1968-2006	144	3498	22358	2980155	2.616	2.277	2.993	2.768	153.922	2.781	2.409e-35	2.34661004	0.96164643
Infliximab	Psoriatic arthropathy	Psoriatic arthropathies	Joint disorders	Musc	1968-2006	16	224	22486	2983429	2.398	1.574	3.533	2.88	18.693	2.881	0.00001535	2.59290387	0.87463506
Infliximab	Psychiatric symptom	Psychiatric symptoms NEC	Psychiatric and behavioural symptoms NEC	Psych	1968-2006	3	656	22499	2982997	0.293	0.114	0.647	0.273	5.822	0.272	0.016	-0.5798737	-1.2275827
Infliximab	Psychomotor hyperactivity	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	3	2467	22499	2981186	0.085	0.033	0.189	0.074	35.036	0.074	3.237e-9	-2.2965987	-2.465104
Infliximab	Psychomotor skills impaired	Nervous system disorders NEC	Neurological disorders NEC	Nerv	1968-2006	1	120	22501	2983533	0.419	0.097	1.307	0.394	0.932	0.394	0.334	0.05876453	-0.8698844
Infliximab	Psychotic disorder	Psychotic disorder NEC	Schizophrenia and other psychotic disorders	Psych	1968-2006	35	9875	22467	2973778	0.44	0.332	0.576	0.434	25.588	0.434	4.226e-7	-1.077962	-0.8209806
Infliximab	Pubic pain	Bone related signs and symptoms	Bone disorders (excl congenital and fractures)	Musc	1968-2006	1	16	22501	2983637	1.029	0.238	3.214	2.759	1.111	2.759	0.292	0.81634411	0.02858746
Infliximab	Pubic rami fracture	Pelvic fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	3	64	22499	2983589	1.433	0.557	3.17	2.328	2.123	2.328	0.145	1.40270905	0.35977015
Infliximab	Pulmonary alveolar haemorrhage	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	6	475	22496	2983178	0.82	0.414	1.492	0.878	0.101	0.878	0.751	0.5945161	-0.1984509
Infliximab	Pulmonary arterial pressure increased	Vascular tests NEC (incl blood pressure)	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	233	22501	2983420	0.404	0.093	1.262	0.372	1.038	0.372	0.308	-0.4712028	-0.9063404
Infliximab	Pulmonary arterial wedge pressure increased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	3	68	22499	2983585	1.695	0.658	3.752	3.343	4.434	3.344	0.035	1.37422192	0.52768274
Infliximab	Pulmonary artery stenosis	Vascular pulmonary disorders NEC	Pulmonary vascular disorders	Resp	1968-2006	1	22	22501	2983631	1.119	0.259	3.501	4.107	2.292	4.107	0.13	0.75997701	0.11243543
Infliximab	Pulmonary calcification	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	4	21	22498	2983632	2.993	1.289	6.266	12.962	30.665	12.962	3.066e-8	2.06359527	1.09627623
Infliximab	Pulmonary cavitation	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	4	51	22498	2983602	2.13	0.929	4.337	4.223	9.076	4.224	0.003	1.81363716	0.75612198
Infliximab	Pulmonary coccidioides	Coccidioides infections	Fungal infectious disorders	Infec	1968-2006	7	8	22495	2983645	11.603	3.504	31.547	39.035	145.646	39.054	1.551e-33	2.83563365	2.45126369
Infliximab	Pulmonary congestion	Pulmonary oedemas	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	31	2644	22471	2981009	0.826	0.611	1.097	0.834	1.005	0.834	0.316	0.59397144	-0.1911605
Infliximab	Pulmonary embolism	Pulmonary thrombotic and embolic conditions	Pulmonary vascular disorders	Resp	1968-2006	220	15118	22282	2968535	1.097	0.98	1.223	1.103	2.082	1.104	0.149	0.91412285	0.09257918
Infliximab	Pulmonary eosinophilia	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	1	661	22501	2982992	0.404	0.093	1.262	0.376	1.04	0.376	0.308	-1.5853263	-0.9063404
Infliximab	Pulmonary fibrosis	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	158	3947	22344	2979706	3.746	3.282	4.262	4.104	340.094	4.132	0	2.31248449	1.3206886
Infliximab	Pulmonary function test abnormal	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	7	218	22495	2983435	2.124	1.126	3.723	3.01	8.807	3.011	0.003	1.56456517	0.7533011
Infliximab	Pulmonary function test decreased	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	2	644	22500	2983009	0.473	0.153	1.187	0.474	1.167	0.474	0.28	-0.9710463	-0.7486599
Infliximab	Pulmonary granuloma	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	14	191	22488	2983462	3.196	2.037	4.829	4.42	33.331	4.422	7.775e-9	2.55426208	1.16190003
Infliximab	Pulmonary haemorrhage	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	21	2283	22481	2981370	0.917	0.635	1.289	0.939	0.082	0.939	0.774	0.25796806	-0.0866478
Infliximab	Pulmonary hilum mass	Mediastinal disorders	Thoracic disorders (excl lung and pleura)	Resp	1968-2006	2	34	22500	2983619	1.405	0.455	3.526	3.156	2.628	3.156	0.105	1.22987801	0.3400373
Infliximab	Pulmonary hypertension	Pulmonary hypertensions	Pulmonary vascular disorders	Resp	1968-2006	45	6901	22457	2976752	0.866	0.674	1.098	0.872	0.829	0.871	0.362	-0.2183462	-0.1438704
Infliximab	Pulmonary infarction	Pulmonary thrombotic and embolic conditions	Pulmonary vascular disorders	Resp	1968-2006	6	505	22496	2983148	0.938	0.474	1.709	1.033	0.006	1.033	0.939	0.52574467	-0.0640053
Infliximab	Pulmonary mass	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	21	184	22481	2983469	4.65	3.213	6.575	6.727	88.262	6.734	5.735e-21	3.10680516	1.53686722
Infliximab	Pulmonary mycosis	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	21	167	22481	2983486	7.249	4.758	11.475	12.987	172.204	12.997	2.443e-39	3.18112882	1.98086353
Infliximab	Pulmonary necrosis	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	2	48	22500	2983605	1.311	0.425	3.288	2.589	1.802	2.589	0.179	1.11543829	0.2707902
Infliximab	Pulmonary oedema	Pulmonary oedemas	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	121	12760	22381	2970893	1.047	0.9	1.213	1.055	0.335	1.055	0.563	0.30759498	0.04592893
Infliximab	Pulmonary sarcoidosis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	7	64	22495	2983589	3.34	1.765	5.905	6.776	30.434	6.778	3.454e-8	2.3742226	1.20597081
Infliximab	Pulmonary sepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	1	26	22501	2983627	0.995	0.23	3.108	2.42	0.826	2.42	0.363	0.72358631	-0.0050125
Infliximab	Pulmonary thrombosis	Pulmonary thrombotic and embolic conditions	Pulmonary vascular disorders	Resp	1968-2006	8	484	22494	2983169	0.981	0.541	1.665	1.061	0.027	1.061	0.87	0.93148868	-0.0191828
Infliximab	Pulmonary toxicity	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	4	380	22498	2983273	0.547	0.239	1.111	0.554	1.4	0.554	0.237	0.35694761	-0.6033065
Infliximab	Pulmonary tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	256	362	22246	2983291	23.119	20.836	25.595	47.502	5589.024	48.149	0	5.5024998	3.14065479
Infliximab	Pulmonary valve incompetence	Pulmonary valvular disorders	Cardiac valve disorders	Card	1968-2006	1	304	22501	2983349	0.372	0.086	1.161	0.332	1.33	0.332	0.249	-0.7260092	-0.9888614
Infliximab	Pulmonary valve sclerosis	Pulmonary valvular disorders	Cardiac valve disorders	Card	1968-2006	1	0	22501	2983653	1.379	0.314	4.39	1090.149	96.106	1097.855	1.089e-22	0.97840063	0.3213586
Infliximab	Pulmonary vascular disorder	Vascular pulmonary disorders NEC	Pulmonary vascular disorders	Resp	1968-2006	3	181	22499	2983472	1.036	0.402	2.289	1.33	0.236	1.33	0.627	0.73975078	0.03536714
Infliximab	Pulmonary vasculitis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	2	54	22500	2983599	1.33	0.431	3.338	2.648	1.959	2.648	0.162	1.06904131	0.28517894
Infliximab	Pulpitis dental	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	9	22501	2983644	1.182	0.273	3.701	6.028	3.834	6.028	0.05	0.88501574	0.16720792
Infliximab	Pulse abnormal	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	2	237	22500	2983416	0.495	0.16	1.241	0.498	0.99	0.498	0.32	0.09426647	-0.7031975
Infliximab	Pulse absent	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	25	1789	22477	2981864	1.034	0.739	1.415	1.063	0.091	1.063	0.763	0.82297963	0.03343478
Infliximab	Pulse pressure abnormal	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	17	22501	2983636	1.163	0.269	3.641	5.467	3.275	5.467	0.07	0.80679534	0.15100287
Infliximab	Pulse pressure decreased	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	4	421	22498	2983232	0.657	0.287	1.334	0.691	0.542	0.691	0.461	0.24694887	-0.4200713
Infliximab	Pulse pressure increased	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	56	22501	2983597	0.762	0.176	2.378	1.134	0.016	1.134	0.9	0.47648884	-0.2718087
Infliximab	Punctate keratitis	Corneal infections, oedemas and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	27	22501	2983626	0.948	0.219	2.96	2.046	0.532	2.046	0.466	0.71463025	-0.0534008
Infliximab	Puncture site abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	1	22501	2983652	1.341	0.307	4.24	59.187	23.6	59.187	1.186e-6	0.967721	0.2934156
Infliximab	Pupil fixed	Pupil disorders	Ocular neuromuscular disorders	Eye	1968-2006	7	876	22495	2982777	0.548	0.29	0.96	0.549	2.533	0.549	0.111	0.06093049	-0.60148
Infliximab	Pupillary reflex impaired	Pupil disorders	Ocular neuromuscular disorders	Eye	1968-2006	2	500	22500	2983153	0.302	0.098	0.758	0.274	3.821	0.274	0.051	-0.6763597	-1.1973283
Infliximab	Pupils unequal	Pupil disorders	Ocular neuromuscular disorders	Eye	1968-2006	2	482	22500	2983171	0.412	0.133	1.033	0.396	1.822	0.396	0.177	-0.6349043	-0.8867319
Infliximab	Purpura	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	28	5343	22474	2978310	0.857	0.624	1.154	0.869	0.545	0.869	0.46	-0.5201418	-0.1543174
Infliximab	Purpura fulminans	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	1	2	22501	2983651	1.318	0.303	4.159	53.611	16.544	53.611	0.00004752	0.95711984	0.27611544
Infliximab	Purulence	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	25	514	22477	2983139	2.572	1.837	3.522	2.968	30.502	2.971	3.335e-8	2.35747829	0.94468381
Infliximab	Purulent discharge	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	14	481	22488	2983172	1.886	1.203	2.847	2.201	8.564	2.201	0.003	1.66155331	0.63445818
Infliximab	Purulent pericarditis	Cardiac infections	Infections - pathogen class unspecified	Infec	1968-2006	3	6	22499	2983647	2.733	1.034	6.384	23.42	36.132	23.42	1.844e-9	1.89509839	1.00539991
Infliximab	Purulent synovitis	Bone and joint infections	Infections - pathogen class unspecified	Infec	1968-2006	1	1	22501	2983652	1.316	0.302	4.15	34.654	15.934	34.654	0.00006558	0.967721	0.27459683
Infliximab	Pustular psoriasis	Psoriatic conditions	Epidermal and dermal conditions	Skin	1968-2006	42	94	22460	2983559	17.361	13.315	22.282	25.534	685.653	25.673	0	4.40244252	2.85422631
Infliximab	Putamen haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	1	19	22501	2983634	1.063	0.246	3.323	3.321	1.467	3.322	0.226	0.78788532	0.0610951
Infliximab	Pyelocaliectasis	Renal structural abnormalities and trauma	Renal disorders (excl nephropathies)	Renal	1968-2006	1	31	22501	2983622	0.833	0.193	2.601	1.424	0.119	1.424	0.731	0.67935182	-0.1827216
Infliximab	Pyelonephritis	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	50	1236	22452	2982417	3.1	2.446	3.885	3.507	81.901	3.515	1.431e-19	2.2514456	1.13140211
Infliximab	Pyelonephritis acute	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	6	207	22496	2983446	1.511	0.763	2.751	1.92	2.521	1.92	0.112	1.42103005	0.41277168
Infliximab	Pyelonephritis chronic	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	48	22501	2983605	0.857	0.198	2.674	1.529	0.174	1.529	0.676	0.53835564	-0.1543174
Infliximab	Pyloric stenosis	Gastric disorders congenital	Gastrointestinal tract disorders congenital	Cong	1968-2006	1	160	22501	2983493	0.503	0.116	1.569	0.522	0.441	0.522	0.507	-0.1517835	-0.6871651
Infliximab	Pyoderma	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	5	44	22497	2983609	2.952	1.393	5.697	6.976	23.818	6.978	1.059e-6	2.12331867	1.08248291
Infliximab	Pyoderma gangrenosum	Skin and subcutaneous tissue ulcerations	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	31	118	22471	2983535	9.35	6.386	13.541	14.807	290.339	14.825	0	3.90822697	2.23537634
Infliximab	Pyomyositis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	17	22500	2983636	1.76	0.569	4.436	7.044	8.865	7.044	0.003	1.38227191	0.56531381
Infliximab	Pyopneumothorax	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	1	4	22501	2983649	1.257	0.29	3.948	14.06	7.755	14.06	0.005	0.93614837	0.22872793
Infliximab	Pyothorax	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	5	52	22497	2983601	2.671	1.264	5.125	5.782	17.405	5.785	0.0000302	2.06145193	0.98245293
Infliximab	Pyramidal tract syndrome	Motor neurone diseases	Neuromuscular disorders	Nerv	1968-2006	3	21	22499	2983632	2.486	0.957	5.608	10.973	22.756	10.985	1.839e-6	1.75079308	0.91067499
Infliximab	Pyrexia	Febrile disorders	Body temperature conditions	Genrl	1968-2006	1220	90096	21282	2893557	1.896	1.809	1.987	1.938	549.526	2.002	0	0.77980598	0.6397464
Infliximab	Pyuria	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	13	616	22489	2983037	3.24	2.03	4.967	4.53	32.933	4.533	9.54e-9	1.28316648	1.17557333
Infliximab	Q fever	Coxiella infections	Rickettsial infectious disorders	Infec	1968-2006	2	12	22500	2983641	2.01	0.644	5.142	17.097	21.45	17.097	3.631e-6	1.43033808	0.69813472
Infliximab	QRS axis abnormal	ECG investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	4	120	22498	2983533	1.382	0.603	2.809	1.916	1.63	1.916	0.202	1.36379139	0.32353173
Infliximab	Quadriparesis	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	3	152	22499	2983501	0.906	0.352	2.002	1.089	0.022	1.089	0.883	0.87790655	-0.098716
Infliximab	Quadriplegia	Paralysis and paresis (excl cranial nerve)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	3	759	22499	2982894	0.507	0.197	1.121	0.511	1.379	0.511	0.24	-0.7561861	-0.6792443
Infliximab	Quadruple vessel bypass graft				1968-2006	2	114	22500	2983539	0.864	0.28	2.165	1.117	0.024	1.117	0.877	0.6723447	-0.1461825
Infliximab	Radial nerve lesion	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	1	3	22501	2983650	1.325	0.304	4.182	45.327	18.099	45.327	0.00002097	0.946596	0.28141246
Infliximab	Radial nerve palsy	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	10	121	22492	2983532	5.556	3.079	10.945	13.791	89.097	13.791	3.759e-21	2.46261182	1.71487842
Infliximab	Radial pulse abnormal	Heart rate and pulse investigations	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	12	22501	2983641	1.137	0.263	3.558	5.014	2.655	5.014	0.103	0.85518395	0.12839321
Infliximab	Radiation injury	Radiation injuries	Injuries by physical agents	Inj&P	1968-2006	3	336	22499	2983317	0.67	0.26	1.481	0.723	0.312	0.723	0.577	0.16626014	-0.4004776
Infliximab	Radicular pain	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	46	22501	2983607	0.774	0.179	2.416	1.176	0.026	1.176	0.871	0.5542459	-0.2561834
Infliximab	Radicular syndrome	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	20	22501	2983633	1.087	0.251	3.397	3.52	1.768	3.52	0.184	0.77852244	0.08342161
Infliximab	Radiculitis	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	41	22501	2983612	0.827	0.191	2.581	1.388	0.105	1.388	0.746	0.59475445	-0.1899506
Infliximab	Radiculopathy	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	6	318	22496	2983335	1.174	0.593	2.138	1.368	0.571	1.368	0.45	1.02015639	0.16041672
Infliximab	Radius fracture	Upper limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	2	152	22500	2983501	0.676	0.219	1.695	0.762	0.142	0.762	0.706	0.46787698	-0.3915622
Infliximab	Rales	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	42	1293	22460	2982360	2.296	1.773	2.935	2.498	35.632	2.502	2.383e-9	1.95630068	0.83116848
Infliximab	Rash	Rashes, eruptions and exanthems NEC	Epidermal and dermal conditions	Skin	1968-2006	415	20370	22087	2963283	0.999	0.921	1.082	1	0	1	0.993	1.38894093	-0.0010005
Infliximab	Rash erythematous	Erythemas	Epidermal and dermal conditions	Skin	1968-2006	103	8911	22399	2974742	1.171	0.994	1.373	1.185	2.925	1.186	0.087	0.58783115	0.15785808
Infliximab	Rash generalised	Rashes, eruptions and exanthems NEC	Epidermal and dermal conditions	Skin	1968-2006	48	4754	22454	2978899	0.651	0.511	0.819	0.648	9.035	0.647	0.003	0.39428448	-0.4292456
Infliximab	Rash macular	Rashes, eruptions and exanthems NEC	Epidermal and dermal conditions	Skin	1968-2006	29	2093	22473	2981560	0.905	0.663	1.213	0.92	0.199	0.92	0.656	0.81746909	-0.0998203
Infliximab	Rash maculo-papular	Rashes, eruptions and exanthems NEC	Epidermal and dermal conditions	Skin	1968-2006	43	17446	22459	2966207	0.881	0.683	1.124	0.889	0.582	0.889	0.446	-1.6032836	-0.1266977
Infliximab	Rash morbilliform	Rashes, eruptions and exanthems NEC	Epidermal and dermal conditions	Skin	1968-2006	5	413	22497	2983240	0.848	0.402	1.62	0.93	0.027	0.93	0.871	0.5281803	-0.1648746
Infliximab	Rash papular	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	28	2109	22474	2981544	0.957	0.696	1.289	0.976	0.016	0.976	0.899	0.75898943	-0.0439519
Infliximab	Rash papulosquamous	Papulosquamous conditions	Epidermal and dermal conditions	Skin	1968-2006	2	15	22500	2983638	1.843	0.595	4.66	9.481	11.745	9.482	0.001	1.40130667	0.61139468
Infliximab	Rash pruritic	Pruritus NEC	Epidermal and dermal conditions	Skin	1968-2006	65	4683	22437	2978970	0.943	0.767	1.151	0.95	0.165	0.95	0.685	0.83987432	-0.058689
Infliximab	Rash pustular	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	28	1995	22474	2981658	1.656	1.205	2.23	1.769	8.997	1.77	0.003	0.83335968	0.50440506
Infliximab	Rash vesicular	Rashes, eruptions and exanthems NEC	Epidermal and dermal conditions	Skin	1968-2006	12	594	22490	2983059	1.296	0.797	2.016	1.419	1.442	1.419	0.23	1.22044356	0.2592826
Infliximab	Raynauds phenomenon	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	16	608	22486	2983045	1.556	1.021	2.291	1.71	4.572	1.711	0.033	1.57276827	0.44211843
Infliximab	Rectal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	8	61	22494	2983592	3.742	2.053	6.443	7.756	40.02	7.759	2.513e-10	2.55832102	1.31962023
Infliximab	Rectal adenoma	Lower gastrointestinal neoplasms benign	Gastrointestinal neoplasms benign	Neopl	1968-2006	2	16	22500	2983637	1.743	0.564	4.393	6.863	8.41	6.864	0.004	1.3917579	0.55560777
Infliximab	Rectal cancer	Rectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	28	208	22474	2983445	5.741	4.151	7.841	8.458	151.659	8.466	7.524e-35	3.37895755	1.74763341
Infliximab	Rectal cancer metastatic	Rectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	17	22500	2983636	1.706	0.552	4.295	6.112	7.421	6.113	0.006	1.38227191	0.53415145
Infliximab	Rectal cancer stage I	Rectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	1	22501	2983652	1.344	0.308	4.253	35.356	25.11	35.356	5.414e-7	0.967721	0.29565024
Infliximab	Rectal cancer stage II	Rectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.393	0.316	4.449	1094.868	133.397	1102.573	7.402e-31	0.97840063	0.33145969
Infliximab	Rectal cancer stage III	Rectal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.27	0.293	3.991	11.181	8.923	11.181	0.003	0.946596	0.2390169
Infliximab	Rectal discharge	Anal and rectal signs and symptoms	Anal and rectal conditions NEC	Gastr	1968-2006	3	90	22499	2983563	1.164	0.452	2.573	1.598	0.65	1.599	0.42	1.22686636	0.15186235
Infliximab	Rectal fistula repair	Anorectal therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	3	22501	2983650	1.315	0.302	4.146	35.458	15.583	35.458	0.00007896	0.946596	0.27383667
Infliximab	Rectal haemorrhage	Intestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	63	7571	22439	2976082	0.813	0.659	0.995	0.815	2.603	0.814	0.107	0.12396587	-0.2070242
Infliximab	Rectal perforation	Anal and rectal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	34	22501	2983619	0.88	0.203	2.746	1.644	0.243	1.644	0.622	0.65344776	-0.1278334
Infliximab	Rectal polyp	Benign neoplasms gastrointestinal (excl oral cavity)	Benign neoplasms gastrointestinal	Gastr	1968-2006	5	134	22497	2983519	1.748	0.829	3.34	2.56	4.396	2.561	0.036	1.54516439	0.55847228
Infliximab	Rectal prolapse	Anal and rectal disorders NEC	Anal and rectal conditions NEC	Gastr	1968-2006	3	95	22499	2983558	1.294	0.503	2.86	1.901	1.253	1.901	0.263	1.19537591	0.2577382
Infliximab	Rectal stenosis	Anal and rectal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	3	11	22499	2983642	2.468	0.95	5.559	11.134	22.171	11.137	2.494e-6	1.84537563	0.90340811
Infliximab	Rectal tenesmus	Anal and rectal signs and symptoms	Anal and rectal conditions NEC	Gastr	1968-2006	4	585	22498	2983068	1.239	0.541	2.517	1.588	0.879	1.588	0.349	-0.1245148	0.2143046
Infliximab	Rectal ulcer	Anal and rectal ulcers and perforation	Gastrointestinal ulceration and perforation	Gastr	1968-2006	4	145	22498	2983508	1.356	0.592	2.755	1.842	1.478	1.843	0.224	1.23014813	0.30453919
Infliximab	Rectocele	Pelvic prolapse conditions	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	99	22501	2983554	0.546	0.126	1.704	0.591	0.274	0.591	0.601	0.18296925	-0.6051363
Infliximab	Recurrent cancer	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	11	234	22491	2983419	2.135	1.285	3.381	2.685	10.82	2.686	0.001	2.07121937	0.75846665
Infliximab	Red blood cell abnormality	Red blood cell abnormal findings NEC	Red blood cell disorders	Blood	1968-2006	2	648	22500	2983005	0.66	0.214	1.653	0.739	0.182	0.739	0.67	-0.9784316	-0.4155154
Infliximab	Red blood cell count	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	3	67	22499	2983586	1.153	0.448	2.549	1.578	0.61	1.579	0.435	1.38129114	0.14236724
Infliximab	Red blood cell count decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	41	3145	22461	2980508	0.877	0.675	1.124	0.884	0.604	0.884	0.437	0.74488768	-0.1312483
Infliximab	Red blood cell count increased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	219	22500	2983434	0.571	0.185	1.432	0.604	0.511	0.604	0.475	0.16571124	-0.5603661
Infliximab	Red blood cell morphology abnormal	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	33	22500	2983620	1.591	0.515	3.999	4.594	5.063	4.595	0.024	1.23841037	0.46436275
Infliximab	Red blood cell schistocytes present	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	214	22501	2983439	0.401	0.093	1.253	0.373	1.063	0.373	0.303	-0.3946284	-0.9137939
Infliximab	Red blood cell sedimentation rate	Haematological analyses NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	9	43	22493	2983610	4.181	2.362	7.08	9.379	52.233	9.399	4.929e-13	2.83677284	1.43055045
Infliximab	Red blood cell sedimentation rate decreased	Haematological analyses NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	1	69	22501	2983584	0.874	0.202	2.728	1.626	0.224	1.626	0.636	0.38129081	-0.1346749
Infliximab	Red blood cell sedimentation rate increased	Haematological analyses NEC	Haematology investigations (incl blood groups)	Inv	1968-2006	110	4632	22392	2979021	2.931	2.5	3.418	3.163	150.961	3.177	1.069e-34	1.59169449	1.07534366
Infliximab	Red blood cells CSF positive	Cerebrospinal fluid tests (excl microbiology)	Neurological and special sense investigations	Inv	1968-2006	2	86	22500	2983567	1	0.324	2.506	1.442	0.262	1.442	0.609	0.84402174	0
Infliximab	Red blood cells urine	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	58	22501	2983595	0.677	0.157	2.114	0.882	0.016	0.882	0.901	0.46142791	-0.390084
Infliximab	Red blood cells urine positive	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	7	120	22495	2983533	2.183	1.157	3.827	3.138	9.59	3.139	0.002	2.02515776	0.78070008
Infliximab	Red cell distribution width	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	3	22501	2983650	1.248	0.288	3.917	10.713	7.056	10.716	0.008	0.946596	0.22154227
Infliximab	Red cell distribution width increased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	2	141	22500	2983512	0.671	0.218	1.682	0.756	0.153	0.756	0.695	0.52414576	-0.3989861
Infliximab	Red man syndrome	Erythemas	Epidermal and dermal conditions	Skin	1968-2006	5	132	22497	2983521	1.986	0.942	3.796	3.151	6.841	3.152	0.009	1.55578926	0.68612257
Infliximab	Reflexes abnormal	Abnormal reflexes	Neurological disorders NEC	Nerv	1968-2006	3	191	22499	2983462	0.956	0.371	2.113	1.18	0.078	1.18	0.779	0.69502085	-0.0449974
Infliximab	Reflux gastritis	Gastritis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	2	50	22500	2983603	1.306	0.423	3.277	2.54	1.769	2.54	0.183	1.09980628	0.26696903
Infliximab	Reflux oesophagitis	Oesophagitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	9	443	22493	2983210	1.079	0.616	1.784	1.175	0.229	1.175	0.632	1.17883716	0.07603469
Infliximab	Refractory anaemia with an excess of blasts	Myelodysplastic syndromes	Leukaemias	Neopl	1968-2006	2	82	22500	2983571	1.202	0.39	3.015	2.075	1.086	2.075	0.297	0.87030356	0.18398684
Infliximab	Refusal of treatment by patient	Social issues	Lifestyle issues	SocCi	1968-2006	27	1702	22475	2981951	0.922	0.667	1.248	0.939	0.106	0.939	0.744	0.99431651	-0.0812101
Infliximab	Refusal of treatment by relative	Social issues	Lifestyle issues	SocCi	1968-2006	3	198	22499	2983455	0.761	0.296	1.682	0.856	0.072	0.856	0.788	0.66451495	-0.2731219
Infliximab	Reiters syndrome	Inflammatory disorders following infection	Ancillary infectious topics	Infec	1968-2006	1	56	22501	2983597	0.844	0.195	2.636	1.476	0.143	1.476	0.705	0.47648884	-0.1696028
Infliximab	Relapsing fever	Borrelial infections	Bacterial infectious disorders	Infec	1968-2006	1	13	22501	2983640	1.136	0.263	3.554	4.753	2.638	4.753	0.104	0.84537553	0.12751332
Infliximab	Renal abscess	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	3	112	22499	2983541	1.271	0.494	2.81	1.859	1.133	1.859	0.287	1.09317465	0.23980399
Infliximab	Renal adenoma	Renal neoplasms benign	Renal and urinary tract neoplasms benign	Neopl	1968-2006	1	8	22501	2983645	1.223	0.282	3.834	7.642	5.477	7.644	0.019	0.89509832	0.20130686
Infliximab	Renal amyloidosis	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	2	22	22500	2983631	1.611	0.522	4.05	4.751	5.414	4.751	0.02	1.33575551	0.4768551
Infliximab	Renal aneurysm	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	30	22501	2983623	1.019	0.236	3.183	2.786	1.016	2.786	0.314	0.68809089	0.01882175
Infliximab	Renal arteriosclerosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	43	22501	2983610	0.829	0.192	2.586	1.394	0.109	1.394	0.742	0.5784143	-0.1875351
Infliximab	Renal artery fibromuscular dysplasia	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	2	22501	2983651	1.283	0.296	4.034	20.651	10.376	20.663	0.001	0.95711984	0.24920109
Infliximab	Renal artery stenosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	6	361	22496	2983292	1.047	0.528	1.906	1.182	0.162	1.182	0.687	0.89056313	0.04592893
Infliximab	Renal artery stent placement	Arterial therapeutic procedures (excl aortic)	Vascular therapeutic procedures	Surg	1968-2006	2	7	22500	2983646	1.87	0.603	4.734	11.415	13.099	11.423	0.0002954	1.48006086	0.62593843
Infliximab	Renal atrophy	Renal structural abnormalities and trauma	Renal disorders (excl nephropathies)	Renal	1968-2006	2	192	22500	2983461	0.592	0.192	1.484	0.636	0.415	0.636	0.519	0.27998306	-0.5242486
Infliximab	Renal cancer metastatic	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	3	43	22499	2983610	1.806	0.701	3.999	3.782	5.738	3.782	0.017	1.56225739	0.59111445
Infliximab	Renal cell carcinoma stage II	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	4	22501	2983649	1.3	0.299	4.094	30.124	12.773	30.124	0.0003516	0.93614837	0.26236426
Infliximab	Renal cell carcinoma stage III	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	9	22501	2983644	1.2	0.277	3.758	6.953	4.447	6.953	0.035	0.88501574	0.18232156
Infliximab	Renal cell carcinoma stage IV	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	49	22501	2983604	0.702	0.162	2.192	0.95	0.003	0.95	0.96	0.53047566	-0.3538219
Infliximab	Renal cell carcinoma stage unspecified	Renal cell carcinomas	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	36	791	22466	2982862	2.634	1.991	3.43	2.981	43.406	2.985	4.448e-11	2.35216783	0.9685036
Infliximab	Renal colic	Urinary tract signs and symptoms NEC	Urinary tract signs and symptoms	Renal	1968-2006	8	1530	22494	2982123	0.956	0.528	1.623	1.029	0.006	1.029	0.936	-0.4869409	-0.0449974
Infliximab	Renal cortical necrosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	71	22501	2983582	0.943	0.218	2.946	2.029	0.507	2.029	0.476	0.36718681	-0.058689
Infliximab	Renal cyst	Renal neoplasms	Renal disorders (excl nephropathies)	Renal	1968-2006	26	952	22476	2982701	1.796	1.291	2.444	1.95	11.435	1.951	0.001	1.68689399	0.58556197
Infliximab	Renal disorder	Renal disorders NEC	Renal disorders (excl nephropathies)	Renal	1968-2006	50	6212	22452	2977441	0.529	0.417	0.662	0.523	21.686	0.522	3.211e-6	0.07743926	-0.6367668
Infliximab	Renal embolism	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	27	22501	2983626	1.055	0.244	3.295	3.064	1.365	3.065	0.243	0.71463025	0.05354077
Infliximab	Renal failure	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	220	25212	22282	2958441	0.808	0.722	0.901	0.805	10.295	0.803	0.001	0.18462756	-0.2131932
Infliximab	Renal failure acute	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	132	22629	22370	2961024	0.58	0.502	0.668	0.574	41.495	0.571	1.181e-10	-0.3875368	-0.5447272
Infliximab	Renal failure chronic	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	14	1912	22488	2981741	0.515	0.328	0.777	0.512	6.453	0.511	0.011	-0.0512956	-0.6635884
Infliximab	Renal function test abnormal	Renal function analyses	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	3	162	22499	2983491	0.943	0.366	2.085	1.156	0.061	1.156	0.805	0.82875806	-0.058689
Infliximab	Renal haematoma	Renal and urinary tract injuries NEC	Injuries NEC	Inj&P	1968-2006	1	63	22501	2983590	0.751	0.174	2.345	1.101	0.009	1.101	0.924	0.42444935	-0.2863496
Infliximab	Renal haemorrhage	Renal disorders NEC	Renal disorders (excl nephropathies)	Renal	1968-2006	1	189	22501	2983464	0.369	0.085	1.151	0.329	1.363	0.329	0.243	-0.2872538	-0.9969586
Infliximab	Renal hypertension	Renal hypertension and related conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	61	22501	2983592	0.873	0.202	2.726	1.624	0.222	1.624	0.637	0.43912725	-0.1358197
Infliximab	Renal hypertrophy	Renal structural abnormalities and trauma	Renal disorders (excl nephropathies)	Renal	1968-2006	1	86	22501	2983567	0.64	0.148	1.997	0.789	0.056	0.789	0.814	0.26558476	-0.4462871
Infliximab	Renal impairment	Renal failure and impairment	Renal disorders (excl nephropathies)	Renal	1968-2006	84	13219	22418	2970434	0.708	0.59	0.843	0.706	10.255	0.704	0.001	-0.2600113	-0.3453112
Infliximab	Renal infarct	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	6	180	22496	2983473	1.691	0.853	3.08	2.272	3.978	2.272	0.046	1.53804895	0.52532007
Infliximab	Renal injury	Renal and urinary tract injuries NEC	Injuries NEC	Inj&P	1968-2006	3	655	22499	2982998	0.207	0.08	0.457	0.186	10.738	0.186	0.001	-0.5780519	-1.5750365
Infliximab	Renal mass	Renal disorders NEC	Renal disorders (excl nephropathies)	Renal	1968-2006	6	106	22496	2983547	2.05	1.035	3.736	3.056	7.699	3.057	0.006	1.91804776	0.71783979
Infliximab	Renal necrosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	81	22501	2983572	0.684	0.158	2.136	0.902	0.011	0.902	0.918	0.29866351	-0.3797974
Infliximab	Renal neoplasm	Urinary tract neoplasms unspecified malignancy NEC	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	8	148	22494	2983505	2.461	1.358	4.181	3.587	13.919	3.588	0.0001908	2.04284199	0.90056777
Infliximab	Renal oncocytoma	Renal neoplasms benign	Renal and urinary tract neoplasms benign	Neopl	1968-2006	1	8	22501	2983645	1.176	0.272	3.681	6.155	3.638	6.155	0.056	0.89509832	0.16211885
Infliximab	Renal pain	Urinary tract signs and symptoms NEC	Urinary tract signs and symptoms	Renal	1968-2006	13	583	22489	2983070	1.041	0.653	1.594	1.1	0.114	1.1	0.735	1.34700361	0.04018179
Infliximab	Renal papillary necrosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	153	22501	2983500	0.814	0.188	2.54	1.332	0.08	1.332	0.777	-0.1170858	-0.2057949
Infliximab	Renal surgery	Renal therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	2	23	22500	2983630	1.518	0.492	3.812	3.982	3.959	3.982	0.047	1.32662952	0.41739368
Infliximab	Renal transplant	Renal therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	2	413	22500	2983240	0.321	0.104	0.805	0.295	3.364	0.295	0.067	-0.4639514	-1.1363142
Infliximab	Renal tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	2	10	22500	2983643	1.887	0.608	4.781	10.785	13.747	10.788	0.0002092	1.45002205	0.63498827
Infliximab	Renal tubular acidosis	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	2	259	22500	2983394	0.494	0.16	1.239	0.496	0.995	0.496	0.319	0.01149153	-0.7052198
Infliximab	Renal tubular disorder	Nephropathies and tubular disorders NEC	Nephropathies	Renal	1968-2006	1	955	22501	2982698	0.143	0.033	0.447	0.104	7.74	0.103	0.005	-2.0391543	-1.9449106
Infliximab	Renal tubular necrosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	20	2931	22482	2980722	0.559	0.384	0.793	0.557	6.986	0.556	0.008	-0.1490822	-0.5816058
Infliximab	Renal vasculitis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	2	99	22500	2983554	1.36	0.441	3.412	2.803	2.211	2.804	0.137	0.76176862	0.3074847
Infliximab	Renal vein thrombosis	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	1	86	22501	2983567	0.603	0.139	1.881	0.704	0.121	0.704	0.728	0.26558476	-0.5058381
Infliximab	Renal vessel disorder	Renal vascular and ischaemic conditions	Renal disorders (excl nephropathies)	Renal	1968-2006	2	126	22500	2983527	0.903	0.293	2.265	1.206	0.068	1.207	0.795	0.60459304	-0.1020327
Infliximab	Reocclusion	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	98	22501	2983555	0.676	0.156	2.111	0.88	0.016	0.88	0.899	0.18915904	-0.3915622
Infliximab	Repetitive strain injury	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	2	11	22500	2983642	2.074	0.661	5.355	21.267	27.315	21.274	1.729e-7	1.4401465	0.72947911
Infliximab	Residual urine volume	Urinary tract function analyses NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	30	22501	2983623	0.887	0.205	2.768	1.679	0.266	1.679	0.606	0.68809089	-0.1199103
Infliximab	Respiration abnormal	Respiratory signs and symptoms NEC	Respiratory disorders NEC	Resp	1968-2006	1	241	22501	2983412	0.272	0.063	0.851	0.223	2.738	0.223	0.098	-0.5022673	-1.3019532
Infliximab	Respiratory acidosis	Conditions associated with abnormal gas exchange	Respiratory disorders NEC	Resp	1968-2006	5	796	22497	2982857	0.704	0.334	1.344	0.743	0.443	0.743	0.506	-0.2327364	-0.3509769
Infliximab	Respiratory arrest	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	69	5776	22433	2977877	0.94	0.769	1.141	0.947	0.204	0.947	0.652	0.63178004	-0.0618754
Infliximab	Respiratory depression	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	3	2058	22499	2981595	0.114	0.044	0.253	0.1	24.394	0.1	7.853e-7	-2.0498505	-2.1715568
Infliximab	Respiratory disorder	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	95	8892	22407	2974761	1.717	1.447	2.026	1.777	30.874	1.78	2.753e-8	0.47662775	0.54057858
Infliximab	Respiratory disorder neonatal	Newborn respiratory disorders NEC	Neonatal respiratory disorders	Resp	1968-2006	3	239	22499	2983414	0.786	0.305	1.737	0.895	0.037	0.895	0.847	0.4977333	-0.2407985
Infliximab	Respiratory distress	Respiratory failures (excl neonatal)	Respiratory disorders NEC	Resp	1968-2006	94	4650	22408	2979003	1.39	1.17	1.641	1.42	11.297	1.422	0.001	1.36653404	0.32930375
Infliximab	Respiratory failure	Respiratory failures (excl neonatal)	Respiratory disorders NEC	Resp	1968-2006	331	10794	22171	2972859	2.089	1.907	2.285	2.154	197.134	2.174	8.817e-45	1.96195379	0.73668548
Infliximab	Respiratory fume inhalation disorder	Chemical injuries	Chemical injury and poisoning	Inj&P	1968-2006	1	36	22501	2983617	0.829	0.192	2.588	1.397	0.11	1.397	0.74	0.63643321	-0.1875351
Infliximab	Respiratory moniliasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	3	116	22499	2983537	1.764	0.685	3.904	3.564	5.222	3.565	0.022	1.07014395	0.56758396
Infliximab	Respiratory rate	Physical examination procedures	Physical examination topics	Inv	1968-2006	1	9	22501	2983644	1.162	0.269	3.638	5.499	3.265	5.5	0.071	0.88501574	0.15014266
Infliximab	Respiratory rate decreased	Physical examination procedures	Physical examination topics	Inv	1968-2006	7	781	22495	2982872	0.624	0.331	1.094	0.638	1.428	0.638	0.232	0.20251661	-0.4716049
Infliximab	Respiratory rate increased	Physical examination procedures	Physical examination topics	Inv	1968-2006	33	2432	22469	2981221	0.839	0.626	1.105	0.847	0.898	0.847	0.343	0.79365357	-0.1755446
Infliximab	Respiratory syncytial virus infection	Respiratory syncytial viral infections	Viral infectious disorders	Infec	1968-2006	1	409	22501	2983244	0.143	0.033	0.448	0.105	7.753	0.105	0.005	-1.0357026	-1.9449106
Infliximab	Respiratory tract carcinoma in situ	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	6	1	22496	2983652	13.534	3.3	39.367	188.809	159.804	189.042	1.249e-36	2.72283242	2.60520504
Infliximab	Respiratory tract congestion	Respiratory tract disorders NEC	Respiratory disorders NEC	Resp	1968-2006	3	323	22499	2983330	0.45	0.175	0.994	0.442	2.084	0.442	0.149	0.20650766	-0.7985077
Infliximab	Respiratory tract infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	44	834	22458	2982819	2.468	1.917	3.137	2.728	44.472	2.732	2.58e-11	2.55991478	0.90340811
Infliximab	Respiratory tract infection bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	5	22501	2983648	1.32	0.303	4.164	21.994	16.551	22.01	0.00004735	0.92577585	0.27763174
Infliximab	Respiratory tract infection fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	32	22501	2983621	0.937	0.217	2.926	2.027	0.475	2.027	0.491	0.67066536	-0.065072
Infliximab	Respiratory tract infection viral	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	2	39	22500	2983614	1.353	0.438	3.394	2.837	2.15	2.838	0.143	1.18795706	0.30232435
Infliximab	Respiratory tract neoplasm	Respiratory tract and pleural neoplasms malignancy unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	30	22501	2983623	1.111	0.257	3.475	4.041	2.14	4.042	0.143	0.68809089	0.10526051
Infliximab	Restless legs syndrome	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	6	830	22496	2982823	0.431	0.218	0.785	0.422	4.658	0.422	0.031	-0.0634014	-0.8416472
Infliximab	Restlessness	Increased physical activity levels	Changes in physical activity	Psych	1968-2006	21	4272	22481	2979381	0.336	0.233	0.473	0.329	28.612	0.328	8.841e-8	-0.6037334	-1.0906441
Infliximab	Restrictive pulmonary disease	Parenchymal lung disorders NEC	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	6	126	22496	2983527	1.978	0.998	3.604	2.883	6.851	2.884	0.009	1.80509149	0.68208623
Infliximab	Retching	Nausea and vomiting symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	13	1909	22489	2981744	0.432	0.271	0.661	0.425	9.996	0.425	0.002	-0.1480251	-0.8393297
Infliximab	Reticulocyte count decreased	Red blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	132	22501	2983521	0.534	0.124	1.668	0.576	0.314	0.576	0.575	-0.0076869	-0.6273594
Infliximab	Reticuloendothelial dysfunction	Reticuloendothelial disorders NEC	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	1	51	22501	2983602	0.932	0.216	2.911	1.967	0.453	1.967	0.501	0.51484364	-0.0704225
Infliximab	Retinal artery embolism	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	41	22501	2983612	0.922	0.213	2.879	1.894	0.404	1.894	0.525	0.59475445	-0.0812101
Infliximab	Retinal artery occlusion	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	4	179	22498	2983474	1.126	0.492	2.288	1.397	0.437	1.397	0.508	1.06622936	0.11867153
Infliximab	Retinal artery thrombosis	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	376	22501	2983277	0.429	0.099	1.341	0.411	0.853	0.411	0.356	-0.9453339	-0.8462984
Infliximab	Retinal degeneration	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	398	22501	2983255	0.558	0.129	1.742	0.618	0.235	0.618	0.628	-1.006204	-0.5833963
Infliximab	Retinal detachment	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	14	1292	22488	2982361	0.893	0.569	1.347	0.923	0.087	0.923	0.769	0.4657018	-0.1131687
Infliximab	Retinal disorder	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	10	1497	22492	2982156	1.157	0.679	1.869	1.265	0.533	1.265	0.465	-0.1704122	0.14583045
Infliximab	Retinal exudates	Retinopathies NEC	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	286	22501	2983367	0.283	0.065	0.884	0.234	2.528	0.234	0.112	-0.6655428	-1.2623084
Infliximab	Retinal haemorrhage	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	8	1710	22494	2981943	0.416	0.229	0.706	0.409	6.8	0.408	0.009	-0.6345712	-0.87707
Infliximab	Retinal oedema	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	350	22501	2983303	0.452	0.104	1.411	0.44	0.705	0.44	0.401	-0.8699215	-0.7940731
Infliximab	Retinal pallor	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	8	22501	2983645	1.229	0.284	3.853	8.929	5.782	8.931	0.016	0.89509832	0.20620083
Infliximab	Retinal scar	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	42	22501	2983611	0.819	0.19	2.557	1.356	0.09	1.356	0.764	0.58656124	-0.1996712
Infliximab	Retinal tear	Retinal structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	3	221	22499	2983432	0.715	0.278	1.581	0.786	0.169	0.786	0.681	0.56859324	-0.3354727
Infliximab	Retinal vascular disorder	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	267	22501	2983386	0.559	0.129	1.744	0.614	0.233	0.614	0.629	-0.5988433	-0.5816058
Infliximab	Retinal vascular occlusion	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	1	66	22501	2983587	0.763	0.176	2.38	1.141	0.016	1.141	0.898	0.40270872	-0.2704972
Infliximab	Retinal vascular thrombosis	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	3	69	22499	2983584	1.369	0.532	3.027	2.125	1.694	2.125	0.193	1.36718715	0.31408055
Infliximab	Retinal vasculitis	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	52	22501	2983601	0.79	0.183	2.467	1.238	0.045	1.238	0.832	0.50709068	-0.2357223
Infliximab	Retinal vein occlusion	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	11	283	22491	2983370	1.985	1.195	3.143	2.425	8.709	2.426	0.003	1.89560635	0.68561891
Infliximab	Retinal vein thrombosis	Retinal bleeding and vascular disorders (excl retinopathy)	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	12	805	22490	2982848	1.477	0.909	2.298	1.656	3.017	1.656	0.082	0.85824648	0.390013
Infliximab	Retinitis	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	3	297	22499	2983356	1.337	0.519	2.956	2.013	1.491	2.013	0.222	0.29053516	0.2904283
Infliximab	Retinopathy	Retinopathies NEC	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	3	649	22499	2983004	0.298	0.116	0.659	0.276	5.619	0.276	0.018	-0.5670722	-1.2106618
Infliximab	Retrograde amnesia	Memory loss (excl dementia)	Mental impairment disorders	Nerv	1968-2006	1	63	22501	2983590	0.656	0.152	2.049	0.828	0.035	0.828	0.852	0.42444935	-0.4215945
Infliximab	Retroperitoneal abscess	Abdominal and gastrointestinal infections	Infections - pathogen class unspecified	Infec	1968-2006	3	32	22499	2983621	2.24	0.867	4.99	7.207	14.056	7.208	0.0001775	1.65344797	0.80647587
Infliximab	Retroperitoneal cancer	Gastrointestinal neoplasms malignant NEC	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	24	22501	2983629	1.143	0.264	3.576	5.164	2.768	5.164	0.096	0.74166694	0.13365638
Infliximab	Retroperitoneal effusion	Peritoneal and retroperitoneal disorders	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	1	1	22501	2983652	1.341	0.307	4.241	108.645	23.837	108.645	1.049e-6	0.967721	0.2934156
Infliximab	Retroperitoneal haemorrhage	Peritoneal and retroperitoneal haemorrhages	Peritoneal and retroperitoneal conditions	Gastr	1968-2006	8	1490	22494	2982163	0.52	0.287	0.882	0.519	3.52	0.519	0.061	-0.4519792	-0.6539265
Infliximab	Reversible posterior leukoencephalopathy syndrome	Encephalopathies NEC	Encephalopathies	Nerv	1968-2006	1	131	22501	2983522	0.585	0.135	1.827	0.667	0.159	0.667	0.69	-0.0022646	-0.5361434
Infliximab	Rhabdomyolysis	Myopathies	Muscle disorders	Musc	1968-2006	24	13844	22478	2969809	0.121	0.086	0.167	0.117	162.663	0.116	2.963e-37	-2.0852729	-2.1119647
Infliximab	Rhesus antibodies positive	Blood grouping and cross-matching analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	31	22501	2983622	1.043	0.241	3.259	3.043	1.25	3.043	0.263	0.67935182	0.04210118
Infliximab	Rheumatic fever	Arthropathies NEC	Joint disorders	Musc	1968-2006	1	35	22501	2983618	0.926	0.214	2.89	1.932	0.422	1.932	0.516	0.64491541	-0.076881
Infliximab	Rheumatoid arthritis	Rheumatoid arthropathies	Joint disorders	Musc	1968-2006	313	3488	22189	2980165	4.955	4.511	5.432	5.623	1044.16	5.694	0	3.40181277	1.60039717
Infliximab	Rheumatoid factor	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	11	22501	2983642	1.174	0.271	3.677	6.34	3.609	6.34	0.057	0.86505951	0.16041672
Infliximab	Rheumatoid factor decreased	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	1	1	22501	2983652	1.314	0.302	4.142	26.063	15.461	26.063	0.00008425	0.967721	0.27307592
Infliximab	Rheumatoid factor increased	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	5	84	22497	2983569	2.173	1.03	4.155	3.76	9.159	3.761	0.002	1.83752599	0.7761087
Infliximab	Rheumatoid factor positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	7	205	22495	2983448	1.892	1.003	3.316	2.533	6.149	2.534	0.013	1.6178444	0.63763447
Infliximab	Rheumatoid lung	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	40	65	22462	2983588	17.676	13.468	22.822	31.816	668.52	31.874	0	4.50997283	2.87220779
Infliximab	Rheumatoid nodule	Rheumatoid arthropathies	Joint disorders	Musc	1968-2006	15	87	22487	2983566	4.434	2.859	6.663	7.117	67.672	7.12	1.931e-16	3.17067173	1.48930211
Infliximab	Rheumatoid vasculitis	Vasculitides NEC	Vascular inflammations	Vasc	1968-2006	6	19	22496	2983634	3.765	1.867	7.169	12.588	44.326	12.593	2.78e-11	2.54902225	1.32574786
Infliximab	Rhinitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	16	11677	22486	2971976	0.631	0.414	0.93	0.633	3.317	0.633	0.069	-2.3970575	-0.4604494
Infliximab	Rhinitis allergic	Nasal congestion and inflammations	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	4	416	22498	2983237	0.68	0.297	1.381	0.72	0.423	0.72	0.515	0.25992303	-0.3856625
Infliximab	Rhinitis seasonal	Nasal congestion and inflammations	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	43	22501	2983610	0.988	0.228	3.084	2.453	0.771	2.453	0.38	0.5784143	-0.0120726
Infliximab	Rhinolaryngitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	5	22501	2983648	1.291	0.297	4.062	18.203	11.246	18.203	0.001	0.92577585	0.25541711
Infliximab	Rhinorrhoea	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	19	1893	22483	2981760	0.621	0.422	0.887	0.622	4.331	0.621	0.037	0.37359109	-0.4764242
Infliximab	Rhonchi	Lower respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	10	420	22492	2983233	1.591	0.935	2.57	1.85	3.795	1.851	0.051	1.37159606	0.46436275
Infliximab	Rib fracture	Thoracic cage fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	26	1087	22476	2982566	1.384	0.995	1.884	1.459	3.608	1.46	0.058	1.5214673	0.32497786
Infliximab	Rift Valley fever	Phleboviral infections	Viral infectious disorders	Infec	1968-2006	2	8	22500	2983645	1.981	0.636	5.052	17.542	19.407	17.542	0.00001056	1.46997828	0.68360177
Infliximab	Right ventricular failure	Right ventricular failures	Heart failures	Card	1968-2006	2	988	22500	2982665	0.168	0.054	0.421	0.141	10.363	0.141	0.001	-1.4985379	-1.7837913
Infliximab	Road traffic accident	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	38	3867	22464	2979786	0.606	0.462	0.784	0.603	9.818	0.602	0.002	0.35477692	-0.5008753
Infliximab	Rocky mountain spotted fever	Spotted fever disorders	Rickettsial infectious disorders	Infec	1968-2006	1	14	22501	2983639	1.119	0.259	3.5	4.123	2.302	4.123	0.129	0.83563334	0.11243543
Infliximab	Rosacea	Rosaceas	Skin appendage conditions	Skin	1968-2006	5	284	22497	2983369	1.039	0.493	1.985	1.201	0.163	1.201	0.686	0.91257604	0.03825871
Infliximab	Rotator cuff syndrome	Joint related disorders NEC	Joint disorders	Musc	1968-2006	6	836	22496	2982817	0.484	0.244	0.882	0.479	3.309	0.479	0.069	-0.0723044	-0.7256704
Infliximab	Rubella	Rubella viral infections	Viral infectious disorders	Infec	1968-2006	1	19	22501	2983634	1.051	0.243	3.284	3.089	1.329	3.09	0.249	0.78788532	0.04974209
Infliximab	Ruptured cerebral aneurysm	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	8	173	22494	2983480	1.887	1.042	3.204	2.437	6.409	2.438	0.011	1.92337107	0.63498827
Infliximab	SAPHO syndrome	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	2	4	22500	2983649	2.189	0.687	5.807	29.549	42.034	29.549	8.97e-11	1.51073838	0.78344482
Infliximab	SLE arthritis	Arthropathies NEC	Joint disorders	Musc	1968-2006	4	13	22498	2983640	3.498	1.447	8.485	17.369	52.073	17.369	5.349e-13	2.13827238	1.25219138
Infliximab	Sacral pain	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	29	22501	2983624	0.897	0.208	2.802	1.751	0.306	1.751	0.58	0.69688322	-0.1086994
Infliximab	Sacroiliitis	Arthropathies NEC	Joint disorders	Musc	1968-2006	6	63	22496	2983590	3.417	1.711	6.335	8.555	33.485	8.558	7.181e-9	2.1957506	1.22876297
Infliximab	Salivary gland cancer	Salivary gland neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	4	51	22498	2983602	2.238	0.976	4.559	4.776	10.766	4.776	0.001	1.81363716	0.80558261
Infliximab	Salivary gland disorder	Salivary gland disorders NEC	Salivary gland conditions	Gastr	1968-2006	1	73	22501	2983580	0.751	0.174	2.343	1.099	0.009	1.099	0.926	0.35321934	-0.2863496
Infliximab	Salivary gland enlargement	Salivary gland enlargements	Salivary gland conditions	Gastr	1968-2006	2	397	22500	2983256	1.062	0.344	2.662	1.614	0.454	1.614	0.501	-0.4212411	0.06015392
Infliximab	Salivary hypersecretion	Salivary gland disorders NEC	Salivary gland conditions	Gastr	1968-2006	4	3294	22498	2980359	0.23	0.1	0.466	0.212	11.613	0.211	0.001	-2.3734451	-1.469676
Infliximab	Salmonella bacteraemia	Salmonella infections	Bacterial infectious disorders	Infec	1968-2006	4	2	22498	2983651	5.369	1.697	30.171	82.919	103.719	82.919	2.332e-24	2.24770402	1.68064167
Infliximab	Salmonella sepsis	Salmonella infections	Bacterial infectious disorders	Infec	1968-2006	11	30	22491	2983623	8.592	4.084	18.824	18.067	139.213	18.074	3.957e-32	3.1879581	2.15083154
Infliximab	Salmonellosis	Salmonella infections	Bacterial infectious disorders	Infec	1968-2006	15	98	22487	2983555	5.079	3.253	7.765	8.694	86.782	8.698	1.212e-20	3.10483202	1.62511439
Infliximab	Salpingitis	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	4	1461	22498	2982192	1.534	0.669	3.116	2.276	2.651	2.276	0.103	-1.2704835	0.4278787
Infliximab	Salpingo-oophorectomy	Fallopian tube therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	24	22501	2983629	1.04	0.241	3.251	2.999	1.22	2.999	0.269	0.74166694	0.03922071
Infliximab	Salpingo-oophoritis	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	4	22501	2983649	1.278	0.295	4.018	12.639	9.707	12.641	0.002	0.93614837	0.24529636
Infliximab	Sarcoidosis	Acute and chronic sarcoidosis	Immune disorders NEC	Immun	1968-2006	22	587	22480	2983066	2.493	1.742	3.481	2.907	25.686	2.909	4.018e-7	2.0377282	0.9134868
Infliximab	Sarcoma	Soft tissue sarcomas histology unspecified	Soft tissue sarcomas	Neopl	1968-2006	7	433	22495	2983220	2.055	1.09	3.603	2.864	8.024	2.865	0.005	0.88678488	0.72027585
Infliximab	Scab	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	14	677	22488	2982976	1.341	0.855	2.024	1.458	1.952	1.458	0.162	1.26990405	0.2934156
Infliximab	Scan abdomen abnormal	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	6	147	22496	2983506	2.182	1.101	3.977	3.38	9.29	3.381	0.002	1.69529607	0.78024189
Infliximab	Scan abnormal	Imaging procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	5	54	22497	2983599	2.829	1.337	5.443	6.868	20.803	6.87	5.089e-6	2.04639102	1.03992329
Infliximab	Scar	Skin injuries and mechanical dermatoses	Epidermal and dermal conditions	Skin	1968-2006	27	2084	22475	2981569	0.813	0.588	1.101	0.822	1.023	0.822	0.312	0.72499072	-0.2070242
Infliximab	Scar pain	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	12	22501	2983641	1.131	0.261	3.538	4.558	2.531	4.558	0.112	0.85518395	0.1231022
Infliximab	Scedosporium infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	2	18	22500	2983635	1.81	0.584	4.569	8.019	10.465	8.02	0.001	1.37284789	0.59332685
Infliximab	Schambergs disease	Pigmentation changes NEC	Pigmentation disorders	Skin	1968-2006	1	17	22501	2983636	1.163	0.269	3.641	5.58	3.25	5.58	0.071	0.80679534	0.15100287
Infliximab	Schizophrenia	Schizophrenia NEC	Schizophrenia and other psychotic disorders	Psych	1968-2006	2	705	22500	2982948	0.22	0.071	0.552	0.19	6.817	0.19	0.009	-1.0797618	-1.5141277
Infliximab	Schizophrenia, paranoid type	Schizophrenia NEC	Schizophrenia and other psychotic disorders	Psych	1968-2006	2	115	22500	2983538	0.832	0.27	2.085	1.05	0.005	1.05	0.945	0.66657562	-0.1839228
Infliximab	Sciatic nerve injury	Peripheral nerve injuries	Injuries NEC	Inj&P	1968-2006	1	50	22501	2983603	0.795	0.184	2.481	1.256	0.051	1.256	0.821	0.52263848	-0.2294132
Infliximab	Sciatica	Lumbar spinal cord and nerve root disorders	Spinal cord and nerve root disorders	Nerv	1968-2006	20	708	22482	2982945	1.609	1.105	2.281	1.755	6.178	1.756	0.013	1.69199133	0.47561287
Infliximab	Scintillating scotoma	Visual disorders NEC	Vision disorders	Eye	1968-2006	1	70	22501	2983583	0.692	0.16	2.159	0.922	0.007	0.922	0.935	0.37422158	-0.3681693
Infliximab	Scleral discolouration	Scleral structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	120	22501	2983533	0.617	0.143	1.926	0.738	0.092	0.738	0.762	0.05876453	-0.4828863
Infliximab	Scleral disorder	Scleral structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	73	22501	2983580	0.71	0.164	2.215	0.971	0.001	0.971	0.977	0.35321934	-0.3424903
Infliximab	Scleritis	Scleral infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	14	257	22488	2983396	4.574	2.899	6.995	7.905	69.463	7.911	7.785e-17	2.2973129	1.5203881
Infliximab	Scleroderma	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	7	495	22495	2983158	1.04	0.552	1.823	1.152	0.136	1.152	0.712	0.73867969	0.03922071
Infliximab	Scleroedema	Skin and subcutaneous conditions NEC	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	1	7	22501	2983646	1.233	0.285	3.868	9.173	6.039	9.173	0.014	0.90525186	0.20945022
Infliximab	Scoliosis	Spine and neck deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	5	336	22497	2983317	0.887	0.421	1.695	0.982	0.002	0.982	0.969	0.74512984	-0.1199103
Infliximab	Scotoma	Visual field disorders	Vision disorders	Eye	1968-2006	13	491	22489	2983162	1.584	0.993	2.424	1.783	4.309	1.784	0.038	1.54150341	0.45995329
Infliximab	Scratch	Skin injuries NEC	Injuries NEC	Inj&P	1968-2006	1	365	22501	2983288	0.207	0.048	0.648	0.159	4.454	0.159	0.035	-0.9139082	-1.5750365
Infliximab	Screaming	Speech articulation and rhythm disturbances	Communication disorders and disturbances	Psych	1968-2006	1	2138	22501	2981515	0.106	0.024	0.331	0.074	11.5	0.074	0.001	-3.100275	-2.2443162
Infliximab	Scrotal abscess	Male reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	18	22501	2983635	1.086	0.251	3.393	3.71	1.749	3.71	0.186	0.79730935	0.08250122
Infliximab	Scrotal erythema	Scrotal disorders NEC	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	13	22501	2983640	1.183	0.273	3.704	6.187	3.83	6.188	0.05	0.84537553	0.16805358
Infliximab	Scrotal gangrene	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.368	0.312	4.344	1085.851	76.534	1093.511	2.164e-18	0.97840063	0.31334982
Infliximab	Scrotal pain	Scrotal disorders NEC	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	96	22501	2983557	0.683	0.158	2.131	0.895	0.012	0.895	0.914	0.20161885	-0.3812604
Infliximab	Scrotal swelling	Scrotal disorders NEC	Penile and scrotal disorders (excl infections and inflammations)	Repro	1968-2006	1	108	22501	2983545	0.628	0.145	1.959	0.764	0.073	0.764	0.786	0.12842453	-0.4652151
Infliximab	Seasonal allergy	Atopic disorders	Allergic conditions	Immun	1968-2006	1	146	22501	2983507	0.434	0.1	1.354	0.416	0.823	0.416	0.364	-0.0815331	-0.8347107
Infliximab	Sebaceous gland disorder	Sebaceous gland disorders	Skin appendage conditions	Skin	1968-2006	1	12	22501	2983641	1.168	0.27	3.657	5.95	3.414	5.95	0.065	0.85518395	0.15529288
Infliximab	Seborrhoea	Sebaceous gland disorders	Skin appendage conditions	Skin	1968-2006	4	776	22498	2982877	1.609	0.702	3.269	2.41	3.217	2.41	0.073	-0.4629745	0.47561287
Infliximab	Seborrhoeic dermatitis	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	5	200	22497	2983453	1.539	0.73	2.94	2.084	2.66	2.085	0.103	1.23233133	0.43113285
Infliximab	Seborrhoeic keratosis	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	2	81	22500	2983572	1.172	0.38	2.94	1.982	0.923	1.982	0.337	0.8769495	0.15871169
Infliximab	Secondary adrenocortical insufficiency	Adrenal cortical hypofunctions	Adrenal gland disorders	Endo	1968-2006	1	28	22501	2983625	0.886	0.205	2.766	1.698	0.265	1.698	0.607	0.70572945	-0.1210383
Infliximab	Secondary amyloidosis	Amyloidoses	Immune disorders NEC	Immun	1968-2006	4	6	22498	2983647	4.256	1.58	19.447	41.36	78.198	41.36	9.321e-19	2.20694394	1.44832975
Infliximab	Secretion discharge	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	8	158	22494	2983495	2.178	1.202	3.7	2.996	9.915	2.997	0.002	1.9938604	0.77840702
Infliximab	Sedation	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	14	36767	22488	2946886	0.167	0.106	0.251	0.161	61.825	0.159	3.754e-15	-4.2320175	-1.7897615
Infliximab	Self mutilation	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	298	22501	2983355	0.218	0.05	0.681	0.168	4.102	0.168	0.043	-0.7061339	-1.5232602
Infliximab	Self-medication	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	4	960	22498	2982693	0.241	0.105	0.49	0.224	10.714	0.224	0.001	-0.7277826	-1.4229583
Infliximab	Seminoma	Testicular neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	5	29	22497	2983624	3.58	1.656	7.281	12.248	43.23	12.255	4.868e-11	2.24699378	1.2753628
Infliximab	Sensation of foreign body	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	6	553	22496	2983100	0.622	0.314	1.132	0.636	1.226	0.636	0.268	0.42210255	-0.4748152
Infliximab	Sensation of heaviness	Musculoskeletal and connective tissue signs and symptoms NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	7	1013	22495	2982640	0.47	0.249	0.824	0.464	4.234	0.464	0.04	-0.1215275	-0.7550226
Infliximab	Sensation of pressure	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	2	569	22500	2983084	0.291	0.094	0.73	0.261	4.132	0.261	0.042	-0.8250795	-1.234432
Infliximab	Sense of oppression	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	3	97	22499	2983556	1.298	0.504	2.871	1.899	1.277	1.899	0.259	1.18296967	0.26082462
Infliximab	Sensorimotor disorder	Neuromuscular disorders NEC	Neuromuscular disorders	Nerv	1968-2006	3	40	22499	2983613	1.794	0.696	3.971	3.799	5.586	3.8	0.018	1.58656148	0.58444776
Infliximab	Sensory disturbance	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	24	1855	22478	2981798	0.747	0.53	1.029	0.752	1.915	0.752	0.166	0.71900105	-0.2916901
Infliximab	Sensory loss	Sensory abnormalities NEC	Neurological disorders NEC	Nerv	1968-2006	14	887	22488	2982766	1.089	0.695	1.644	1.152	0.272	1.152	0.602	0.94249426	0.08525984
Infliximab	Sepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	608	20994	21894	2962659	3.15	2.946	3.366	3.326	931.274	3.398	0	1.88322164	1.14740245
Infliximab	Sepsis neonatal	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	1	217	22501	2983436	0.316	0.073	0.987	0.268	2	0.268	0.157	-0.4069925	-1.1520131
Infliximab	Sepsis syndrome	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	5	57	22497	2983596	2.567	1.216	4.921	5.29	15.418	5.291	0.00008618	2.02409037	0.9427379
Infliximab	Septic arthritis neisserial	Neisseria infections	Bacterial infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.36	0.311	4.311	1082.489	65.988	1090.101	4.537e-16	0.97840063	0.3074847
Infliximab	Septic arthritis staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	9	47	22493	2983606	5.005	2.746	9.405	12.742	74.732	12.746	5.39e-18	2.80600792	1.61043741
Infliximab	Septic arthritis streptobacillus	Streptobacillus infections	Bacterial infectious disorders	Infec	1968-2006	1	3	22501	2983650	1.306	0.3	4.114	26.197	13.708	26.197	0.0002135	0.946596	0.26696903
Infliximab	Septic embolus	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	8	110	22494	2983543	2.755	1.519	4.683	4.358	18.701	4.36	0.00001529	2.2457934	1.01341744
Infliximab	Septic shock	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	138	2541	22364	2981112	2.647	2.297	3.037	2.808	151.274	2.824	9.129e-35	2.7109067	0.97342692
Infliximab	Seroma	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	123	22499	2983530	1.159	0.45	2.562	1.586	0.627	1.586	0.428	1.0307041	0.14755756
Infliximab	Serositis	Inflammations	General system disorders NEC	Genrl	1968-2006	4	35	22498	2983618	2.655	1.154	5.449	7.971	19.689	7.973	0.00000911	1.94154539	0.97644465
Infliximab	Serratia infection	Serratia infections	Bacterial infectious disorders	Infec	1968-2006	9	114	22493	2983539	2.525	1.441	4.176	3.595	15.55	3.596	0.00008036	2.36940456	0.92624106
Infliximab	Serum ferritin	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	1	10	22501	2983643	1.115	0.258	3.487	4.205	2.222	4.207	0.136	0.87500312	0.1088544
Infliximab	Serum ferritin decreased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	3	120	22499	2983533	1.115	0.433	2.464	1.497	0.468	1.497	0.494	1.04747507	0.1088544
Infliximab	Serum ferritin increased	Mineral and electrolyte analyses	Water, electrolyte and mineral investigations	Inv	1968-2006	6	547	22496	2983106	0.709	0.358	1.291	0.742	0.536	0.741	0.464	0.43465807	-0.3438998
Infliximab	Serum sickness	Allergic conditions NEC	Allergic conditions	Immun	1968-2006	127	701	22375	2982952	11.999	10.264	13.921	15.755	1333.821	15.883	0	4.14125083	2.48482331
Infliximab	Sexual dysfunction	Sexual function and fertility disorders NEC	Sexual function and fertility disorders	Repro	1968-2006	1	1697	22501	2981956	0.074	0.017	0.232	0.051	17.694	0.051	0.00002595	-2.7888216	-2.6036902
Infliximab	Shift to the left	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	11	133	22491	2983520	2.876	1.73	4.557	4.154	23.295	4.156	1.389e-6	2.51894105	1.05640044
Infliximab	Shock	Circulatory collapse and shock	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	103	14777	22399	2968876	1.212	1.028	1.421	1.228	4.274	1.229	0.039	-0.1298213	0.19227189
Infliximab	Shock haemorrhagic	Circulatory collapse and shock	Decreased and nonspecific blood pressure disorders and shock	Vasc	1968-2006	7	330	22495	2983323	0.982	0.521	1.721	1.074	0.035	1.074	0.851	1.17238087	-0.018164
Infliximab	Short-bowel syndrome	Malabsorption syndromes	Malabsorption conditions	Gastr	1968-2006	5	14	22497	2983639	3.507	1.629	7.047	13.287	41.161	13.292	1.402e-10	2.3822721	1.25476097
Infliximab	Shoulder arthroplasty	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	5	46	22497	2983607	2.754	1.302	5.291	6.247	19.196	6.248	0.0000118	2.10760152	1.0130544
Infliximab	Shoulder deformity	Trunk deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	1	11	22501	2983642	1.178	0.272	3.689	6.033	3.7	6.033	0.054	0.86505951	0.16381809
Infliximab	Shoulder dystocia	Foetal position and presentation abnormalities	Foetal complications	Preg	1968-2006	1	22	22501	2983631	1.046	0.242	3.267	3.125	1.276	3.125	0.259	0.75997701	0.04497337
Infliximab	Shoulder operation	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	4	74	22498	2983579	1.718	0.75	3.491	2.775	4.187	2.776	0.041	1.64761223	0.54116082
Infliximab	Shoulder pain				1968-2006	10	1033	22492	2982620	0.648	0.381	1.047	0.658	1.754	0.658	0.185	0.30941333	-0.4338646
Infliximab	Shunt infection	Vascular infections	Infections - pathogen class unspecified	Infec	1968-2006	2	23	22500	2983630	1.601	0.518	4.023	4.707	5.231	4.707	0.022	1.32662952	0.47062843
Infliximab	Sialoadenitis	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	3	435	22499	2983218	1.428	0.555	3.157	2.335	2.075	2.335	0.15	-0.1081765	0.35627486
Infliximab	Sicca syndrome	Lacrimal disorders	Eye disorders NEC	Eye	1968-2006	1	44	22501	2983609	0.943	0.218	2.944	2.008	0.503	2.008	0.478	0.5703131	-0.058689
Infliximab	Sick sinus syndrome	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	14	568	22488	2983085	1.618	1.032	2.443	1.828	4.939	1.829	0.026	1.47449895	0.48119082
Infliximab	Sickle cell anaemia	Haemoglobinopathies congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	4	70	22498	2983583	1.832	0.8	3.726	3.071	5.322	3.071	0.021	1.67514796	0.60540827
Infliximab	Sickle cell anaemia with crisis	Haemoglobinopathies congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	3	88	22499	2983565	1.191	0.463	2.632	1.673	0.759	1.673	0.384	1.23965753	0.17479329
Infliximab	Sideroblastic anaemia	Anaemias NEC	Anaemias nonhaemolytic and marrow depression	Blood	1968-2006	1	51	22501	2983602	0.842	0.195	2.629	1.468	0.139	1.468	0.709	0.51484364	-0.1719753
Infliximab	Sigmoidectomy	Large intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	9	22501	2983644	1.18	0.273	3.695	6.703	3.771	6.703	0.052	0.88501574	0.16551444
Infliximab	Sigmoiditis	Colitis (excl infective)	Gastrointestinal inflammatory conditions	Gastr	1968-2006	4	64	22498	2983589	1.857	0.81	3.775	3.201	5.591	3.201	0.018	1.71746262	0.61896228
Infliximab	Silicosis	Chest and lung injuries NEC	Injuries NEC	Inj&P	1968-2006	3	8	22499	2983645	2.92	1.08	7.303	29.049	47.678	29.067	5.022e-12	1.8750032	1.07158362
Infliximab	Simple partial seizures	Partial simple seizures NEC	Seizures (incl subtypes)	Nerv	1968-2006	1	434	22501	2983219	0.204	0.047	0.637	0.155	4.573	0.155	0.032	-1.1005839	-1.5896353
Infliximab	Sinoatrial block	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	2	173	22500	2983480	0.693	0.225	1.737	0.792	0.106	0.792	0.745	0.36619082	-0.3667253
Infliximab	Sinus arrest	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	2	352	22500	2983301	0.451	0.146	1.131	0.444	1.377	0.444	0.241	-0.2938639	-0.7962879
Infliximab	Sinus arrhythmia	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	2	408	22500	2983245	0.383	0.124	0.961	0.361	2.215	0.361	0.137	-0.4507398	-0.9597203
Infliximab	Sinus bradycardia	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	10	2495	22492	2981158	0.426	0.25	0.688	0.419	7.944	0.419	0.005	-0.8564457	-0.8533159
Infliximab	Sinus cancer metastatic	Paranasal sinus and nasal cavity neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	2	22501	2983651	1.331	0.305	4.203	26.251	19.88	26.251	8.245e-6	0.95711984	0.28593054
Infliximab	Sinus congestion	Paranasal sinus disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	6	720	22496	2982933	0.52	0.262	0.946	0.522	2.621	0.522	0.105	0.11037685	-0.6539265
Infliximab	Sinus disorder	Paranasal sinus disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	15	715	22487	2982938	1.091	0.706	1.626	1.15	0.286	1.151	0.593	1.29632588	0.08709471
Infliximab	Sinus headache	Headaches NEC	Headaches	Nerv	1968-2006	6	533	22496	2983120	0.661	0.334	1.203	0.685	0.872	0.685	0.35	0.46438611	-0.4140014
Infliximab	Sinus operation	Paranasal therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	6	153	22496	2983500	1.501	0.758	2.734	1.913	2.464	1.913	0.117	1.66540154	0.40613155
Infliximab	Sinus polyp	Paranasal sinus disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	3	51	22499	2983602	1.809	0.703	4.006	3.813	5.78	3.814	0.016	1.49937944	0.59277421
Infliximab	Sinus tachycardia	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	48	2977	22454	2980676	1.059	0.831	1.332	1.076	0.249	1.076	0.617	1.0390855	0.05732507
Infliximab	Sinusitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	136	7245	22366	2976408	1.616	1.401	1.857	1.66	34.209	1.664	4.95e-9	1.26992796	0.47995396
Infliximab	Sinusitis aspergillus	Aspergillus infections	Fungal infectious disorders	Infec	1968-2006	1	13	22501	2983640	1.194	0.276	3.741	6.301	4.222	6.302	0.04	0.84537553	0.17730901
Infliximab	Sinusitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	12	22501	2983641	1.148	0.265	3.593	4.814	2.896	4.815	0.089	0.85518395	0.1380213
Infliximab	Sinusitis fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	13	22501	2983640	1.117	0.258	3.494	4.332	2.263	4.333	0.132	0.84537553	0.11064652
Infliximab	Sjogrens syndrome	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	16	264	22486	2983389	2.788	1.83	4.108	3.527	26.716	3.528	2.357e-7	2.44614126	1.02532449
Infliximab	Skeleton dysplasia	Non-site specific bone disorders congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	1	14	22501	2983639	1.141	0.264	3.568	4.602	2.71	4.604	0.1	0.83563334	0.13190507
Infliximab	Skin atrophy	Skin hypoplasias and atrophies	Cornification and dystrophic skin disorders	Skin	1968-2006	3	831	22499	2982822	0.599	0.233	1.323	0.628	0.655	0.628	0.418	-0.8677777	-0.5124937
Infliximab	Skin bacterial infection	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	25	22501	2983628	0.928	0.215	2.898	1.964	0.435	1.964	0.51	0.7325983	-0.0747235
Infliximab	Skin burning sensation	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	4	506	22498	2983147	0.422	0.184	0.858	0.413	3.308	0.413	0.069	0.04255744	-0.86275
Infliximab	Skin cancer	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	93	963	22409	2982690	9.115	7.543	10.973	12.944	742.49	13.006	0	3.38874728	2.20992141
Infliximab	Skin candida	Candida infections	Fungal infectious disorders	Infec	1968-2006	1	121	22501	2983532	0.86	0.199	2.684	1.549	0.184	1.549	0.668	0.05310852	-0.1508229
Infliximab	Skin depigmentation	Hypopigmentation disorders	Pigmentation disorders	Skin	1968-2006	1	152	22501	2983501	0.493	0.114	1.538	0.503	0.487	0.503	0.485	-0.1120602	-0.7072461
Infliximab	Skin discolouration	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	45	10841	22457	2972812	0.669	0.521	0.848	0.668	7.372	0.667	0.007	-0.8585893	-0.4019712
Infliximab	Skin disorder	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	34	6401	22468	2977252	0.832	0.624	1.091	0.839	1.031	0.839	0.31	-0.5043007	-0.1839228
Infliximab	Skin exfoliation	Exfoliative conditions	Epidermal and dermal conditions	Skin	1968-2006	22	2618	22480	2981035	0.607	0.424	0.847	0.607	5.547	0.607	0.019	0.13563764	-0.4992265
Infliximab	Skin fibrosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	26	22501	2983627	0.991	0.229	3.096	2.456	0.798	2.456	0.372	0.72358631	-0.0090407
Infliximab	Skin fissures	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	4	270	22498	2983383	0.785	0.343	1.595	0.862	0.086	0.862	0.769	0.70168785	-0.2420716
Infliximab	Skin graft	Skin grafts	Skin and subcutaneous tissue therapeutic procedures	Surg	1968-2006	13	245	22489	2983408	2.397	1.502	3.671	3.027	16.277	3.028	0.00005473	2.24489925	0.87421796
Infliximab	Skin graft infection	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	1	13	22501	2983640	1.143	0.264	3.576	5.047	2.777	5.047	0.096	0.84537553	0.13365638
Infliximab	Skin graft rejection	Transplant rejections	Immune disorders NEC	Immun	1968-2006	1	1	22501	2983652	1.324	0.304	4.179	46.734	17.937	46.734	0.00002284	0.967721	0.28065746
Infliximab	Skin haemorrhage	Skin haemorrhages	Skin vascular abnormalities	Skin	1968-2006	1	298	22501	2983355	0.251	0.058	0.784	0.202	3.196	0.202	0.074	-0.7061339	-1.3823023
Infliximab	Skin hyperpigmentation	Hyperpigmentation disorders	Pigmentation disorders	Skin	1968-2006	4	669	22498	2982984	0.339	0.148	0.688	0.323	5.633	0.323	0.018	-0.2832126	-1.0817552
Infliximab	Skin induration	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	56	22501	2983597	0.668	0.155	2.085	0.86	0.023	0.86	0.879	0.47648884	-0.4034671
Infliximab	Skin infection	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	26	503	22476	2983150	2.799	2.013	3.811	3.278	38.147	3.281	6.561e-10	2.43354199	1.02926221
Infliximab	Skin inflammation	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	1	244	22501	2983409	0.338	0.078	1.056	0.289	1.707	0.289	0.191	-0.5137463	-1.0847094
Infliximab	Skin injury	Skin injuries NEC	Injuries NEC	Inj&P	1968-2006	1	207	22501	2983446	0.301	0.069	0.94	0.25	2.239	0.25	0.135	-0.36536	-1.200645
Infliximab	Skin irritation	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	2	760	22500	2982893	0.218	0.071	0.546	0.188	6.946	0.188	0.008	-1.171224	-1.5232602
Infliximab	Skin laceration	Skin injuries NEC	Injuries NEC	Inj&P	1968-2006	7	780	22495	2982873	0.505	0.268	0.884	0.501	3.396	0.501	0.065	0.20408338	-0.6831968
Infliximab	Skin lesion	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	47	1872	22455	2981781	1.682	1.317	2.122	1.764	14.904	1.765	0.0001131	1.63170633	0.51998356
Infliximab	Skin lesion excision	Skin lesion excisions	Skin and subcutaneous tissue therapeutic procedures	Surg	1968-2006	1	11	22501	2983642	1.155	0.267	3.614	4.956	3.06	4.956	0.08	0.86505951	0.14410034
Infliximab	Skin necrosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	14	1881	22488	2981772	1.006	0.642	1.519	1.054	0.038	1.054	0.845	-0.0294008	0.00598207
Infliximab	Skin neoplasm excision	Skin lesion excisions	Skin and subcutaneous tissue therapeutic procedures	Surg	1968-2006	8	41	22494	2983612	5.52	2.77	13.347	17.547	85.802	17.55	1.988e-20	2.70828157	1.70837786
Infliximab	Skin nodule	Skin and subcutaneous conditions NEC	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	17	956	22485	2982697	2.028	1.348	2.955	2.333	12.233	2.334	0.0004695	1.10843401	0.70705009
Infliximab	Skin odour abnormal	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	1124	22501	2982529	0.201	0.046	0.628	0.151	4.683	0.151	0.03	-2.2472581	-1.6044504
Infliximab	Skin oedema	Skin vascular conditions NEC	Skin vascular abnormalities	Skin	1968-2006	1	75	22501	2983578	0.651	0.151	2.032	0.815	0.041	0.815	0.84	0.33938578	-0.4292456
Infliximab	Skin papilloma	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	7	234	22495	2983419	1.61	0.854	2.821	2.014	3.431	2.015	0.064	1.50158125	0.47623418
Infliximab	Skin reaction	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	10	664	22492	2982989	0.842	0.495	1.361	0.879	0.165	0.879	0.685	0.85250538	-0.1719753
Infliximab	Skin striae	Skin hypoplasias and atrophies	Cornification and dystrophic skin disorders	Skin	1968-2006	2	331	22500	2983322	0.851	0.276	2.133	1.09	0.014	1.09	0.904	-0.2303413	-0.1613432
Infliximab	Skin swelling	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	81	22501	2983572	0.577	0.133	1.801	0.65	0.182	0.65	0.67	0.29866351	-0.549913
Infliximab	Skin test positive	Immunology skin tests NEC	Immunology and allergy investigations	Inv	1968-2006	5	543	22497	2983110	0.623	0.295	1.19	0.641	0.978	0.641	0.323	0.22281227	-0.4732088
Infliximab	Skin tightness	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	123	22501	2983530	0.439	0.102	1.372	0.418	0.786	0.418	0.375	0.04186259	-0.8232559
Infliximab	Skin ulcer	Skin and subcutaneous tissue ulcerations	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	70	4098	22432	2979555	1.742	1.427	2.11	1.818	24.476	1.82	7.526e-7	1.12799131	0.55503388
Infliximab	Skin ulcer haemorrhage	Skin and subcutaneous tissue ulcerations	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	3	13	22499	2983640	2.496	0.96	5.634	13.53	23.295	13.533	0.00000139	1.8259566	0.91468945
Infliximab	Skin warm	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	8	483	22494	2983170	1.035	0.571	1.757	1.129	0.117	1.129	0.733	0.93379713	0.03440143
Infliximab	Skin wrinkling	Skin dystrophies	Cornification and dystrophic skin disorders	Skin	1968-2006	1	145	22501	2983508	0.487	0.112	1.519	0.496	0.517	0.496	0.472	-0.0763819	-0.7194912
Infliximab	Skull fracture	Skull fractures, facial bone fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	1	186	22501	2983467	0.387	0.089	1.209	0.352	1.187	0.352	0.276	-0.273815	-0.9493306
Infliximab	Sleep apnoea syndrome	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	16	1596	22486	2982057	0.722	0.474	1.064	0.732	1.542	0.732	0.214	0.36807118	-0.3257301
Infliximab	Sleep disorder	Sleep disorders NEC	Sleep disorders and disturbances	Psych	1968-2006	25	5566	22477	2978087	0.351	0.251	0.481	0.344	31.066	0.343	2.494e-8	-0.7343282	-1.0469691
Infliximab	Sluggishness	Asthenic conditions	General system disorders NEC	Genrl	1968-2006	3	520	22499	2983133	0.369	0.143	0.816	0.352	3.533	0.352	0.06	-0.308228	-0.9969586
Infliximab	Small cell carcinoma	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	4	32	22498	2983621	2.663	1.157	5.467	7.751	19.933	7.753	0.00000802	1.96684382	0.97945331
Infliximab	Small cell lung cancer extensive stage	Respiratory tract small cell carcinomas	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	15	22500	2983638	1.883	0.607	4.769	9.857	13.548	9.858	0.0002326	1.40130667	0.63286625
Infliximab	Small cell lung cancer metastatic	Respiratory tract small cell carcinomas	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	5	23	22497	2983630	3.362	1.572	6.639	10.932	35.974	10.935	1.999e-9	2.2995931	1.21253603
Infliximab	Small cell lung cancer stage unspecified	Respiratory tract small cell carcinomas	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	17	182	22485	2983471	3.933	2.611	5.745	5.458	57.007	5.462	4.342e-14	2.84309438	1.36940249
Infliximab	Small for dates baby	Gestational age and weight conditions	Neonatal and perinatal conditions	Preg	1968-2006	7	885	22495	2982768	0.587	0.311	1.029	0.595	1.909	0.594	0.167	0.04821005	-0.5327305
Infliximab	Small intestinal haemorrhage	Intestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	1	188	22501	2983465	0.4	0.093	1.25	0.367	1.073	0.367	0.3	-0.2827881	-0.9162907
Infliximab	Small intestinal obstruction	Duodenal and small intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	62	962	22440	2982691	3.432	2.775	4.207	3.894	120.889	3.902	4.042e-28	2.8507803	1.23314318
Infliximab	Small intestinal perforation	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	5	231	22497	2983422	1.624	0.77	3.102	2.25	3.317	2.251	0.069	1.10593192	0.48489224
Infliximab	Small intestinal resection	Small intestine therapeutic procedures	Gastrointestinal therapeutic procedures	Surg	1968-2006	4	28	22498	2983625	2.779	1.205	5.731	9.422	23.344	9.423	1.355e-6	2.0012802	1.02209115
Infliximab	Small intestinal stenosis	Duodenal and small intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	8	39	22494	2983614	5.361	2.725	12.48	14.966	82.849	14.972	8.856e-20	2.7241718	1.67915052
Infliximab	Small intestinal ulcer haemorrhage	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	2	10	22500	2983643	2.018	0.646	5.168	15.822	22.147	15.825	2.525e-6	1.45002205	0.70210692
Infliximab	Small intestine carcinoma	Small intestinal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	9	41	22493	2983612	5.294	2.855	10.724	14.495	81.917	14.5	1.419e-19	2.85240483	1.6665741
Infliximab	Small intestine carcinoma metastatic	Small intestinal neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	2	8	22500	2983645	1.977	0.635	5.041	13.554	19.093	13.554	0.00001245	1.46997828	0.68158054
Infliximab	Small intestine ulcer	Intestinal ulcers and perforation NEC	Gastrointestinal ulceration and perforation	Gastr	1968-2006	1	74	22501	2983579	0.774	0.179	2.415	1.176	0.026	1.176	0.871	0.34628598	-0.2561834
Infliximab	Smear cervix abnormal	Reproductive organ and breast histopathology procedures	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	8	732	22494	2982921	1.498	0.827	2.543	1.792	2.65	1.793	0.104	0.44963348	0.40413089
Infliximab	Smoker	Tobacco use	Lifestyle issues	SocCi	1968-2006	2	112	22500	2983541	0.869	0.282	2.18	1.13	0.029	1.13	0.865	0.6839525	-0.1404122
Infliximab	Smooth muscle antibody positive	Autoimmunity analyses	Immunology and allergy investigations	Inv	1968-2006	5	89	22497	2983564	2.163	1.025	4.135	3.768	9.03	3.769	0.003	1.80547595	0.77149615
Infliximab	Sneezing	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	1	1030	22501	2982623	0.098	0.023	0.308	0.068	12.592	0.068	0.0003875	-2.1352269	-2.3227878
Infliximab	Snoring	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	1	432	22501	2983221	0.21	0.048	0.657	0.16	4.344	0.16	0.037	-1.0954994	-1.5606477
Infliximab	Social avoidant behaviour	Behaviour and socialisation disturbances	Personality disorders and disturbances in behaviour	Psych	1968-2006	2	796	22500	2982857	0.183	0.059	0.46	0.155	9.077	0.155	0.003	-1.2280978	-1.6982691
Infliximab	Sodium retention	Sodium imbalance	Electrolyte and fluid balance conditions	Metab	1968-2006	1	50	22501	2983603	0.822	0.19	2.567	1.372	0.096	1.372	0.756	0.52263848	-0.1960149
Infliximab	Soft tissue disorder	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	4	184	22498	2983469	1.293	0.564	2.626	1.724	1.134	1.724	0.287	1.04362046	0.2569651
Infliximab	Soft tissue haemorrhage	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	32	22501	2983621	0.95	0.22	2.968	2.07	0.545	2.07	0.461	0.67066536	-0.0512933
Infliximab	Soft tissue infection	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	4	156	22498	2983497	1.406	0.614	2.857	1.95	1.768	1.95	0.184	1.17505142	0.34074879
Infliximab	Soft tissue injury	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	69	22501	2983584	0.727	0.168	2.269	1.023	0	1.023	0.982	0.38129081	-0.3188288
Infliximab	Soft tissue necrosis	Soft tissue disorders NEC	Musculoskeletal and connective tissue disorders NEC	Musc	1968-2006	1	16	22501	2983637	1.13	0.261	3.535	4.69	2.502	4.69	0.114	0.81634411	0.12221763
Infliximab	Solar elastosis	Skin preneoplastic conditions NEC	Cornification and dystrophic skin disorders	Skin	1968-2006	1	6	22501	2983647	1.258	0.29	3.949	12.958	7.746	12.964	0.005	0.91547736	0.22952316
Infliximab	Solar urticaria	Urticarias	Angioedema and urticaria	Skin	1968-2006	1	8	22501	2983645	1.186	0.274	3.714	6.922	3.97	6.922	0.046	0.89509832	0.1705863
Infliximab	Somnolence	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	61	14408	22441	2969245	0.222	0.179	0.272	0.216	174.711	0.214	6.924e-40	-0.8358406	-1.5050779
Infliximab	Speech disorder	Speech and language abnormalities	Neurological disorders NEC	Nerv	1968-2006	48	11803	22454	2971850	0.51	0.4	0.642	0.504	23.175	0.503	1.479e-6	-0.8890183	-0.6733446
Infliximab	Sperm analysis abnormal	Fertility analyses	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	2	11	22500	2983642	1.996	0.64	5.101	15.55	20.396	15.557	6.295e-6	1.4401465	0.69114518
Infliximab	Spermatozoa morphology abnormal	Fertility analyses	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	7	22501	2983646	1.224	0.282	3.836	8.545	5.528	8.545	0.019	0.90525186	0.20212418
Infliximab	Spermatozoa progressive motility decreased	Fertility analyses	Reproductive organ and breast investigations (excl hormone analyses)	Inv	1968-2006	1	36	22501	2983617	0.934	0.216	2.917	1.98	0.461	1.98	0.497	0.63643321	-0.0682788
Infliximab	Spider naevus	Telangiectasia and related conditions	Skin vascular abnormalities	Skin	1968-2006	1	91	22501	2983562	0.71	0.164	2.215	0.972	0.001	0.972	0.977	0.23324737	-0.3424903
Infliximab	Spinal X-ray abnormal	Musculoskeletal and soft tissue imaging procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	1	22	22501	2983631	1.077	0.249	3.366	3.611	1.641	3.611	0.2	0.75997701	0.0741794
Infliximab	Spinal claudication	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	68	22501	2983585	0.994	0.23	3.104	2.436	0.811	2.437	0.368	0.38839484	-0.0060181
Infliximab	Spinal column stenosis	Spine and neck deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	14	661	22488	2982992	1.337	0.853	2.018	1.455	1.915	1.456	0.166	1.29818019	0.2904283
Infliximab	Spinal compression fracture	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	22	615	22480	2983038	1.883	1.315	2.629	2.086	11.79	2.089	0.001	1.98431751	0.63286625
Infliximab	Spinal cord compression	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	10	360	22492	2983293	1.505	0.884	2.431	1.735	2.982	1.735	0.084	1.53401973	0.4087929
Infliximab	Spinal cord disorder	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	4	284	22498	2983369	0.763	0.333	1.55	0.833	0.133	0.833	0.715	0.65295972	-0.2704972
Infliximab	Spinal cord infection	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	7	22501	2983646	1.186	0.274	3.712	6.702	3.958	6.702	0.047	0.90525186	0.1705863
Infliximab	Spinal cord injury cervical	Spinal cord injuries NEC	Injuries NEC	Inj&P	1968-2006	1	24	22501	2983629	1.064	0.246	3.324	3.322	1.472	3.322	0.225	0.74166694	0.06203539
Infliximab	Spinal cord injury thoracic	Spinal cord injuries NEC	Injuries NEC	Inj&P	1968-2006	1	7	22501	2983646	1.287	0.296	4.05	18.715	10.766	18.715	0.001	0.90525186	0.25231393
Infliximab	Spinal cord ischaemia	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	1	12	22501	2983641	1.126	0.26	3.521	4.547	2.419	4.547	0.12	0.85518395	0.11867153
Infliximab	Spinal cord neoplasm	Nervous system neoplasms unspecified malignancy NEC	Nervous system neoplasms malignant and unspecified NEC	Neopl	1968-2006	2	41	22500	2983612	1.176	0.381	2.95	2.026	0.954	2.026	0.329	1.17152386	0.16211885
Infliximab	Spinal disorder	Bone disorders NEC	Bone disorders (excl congenital and fractures)	Musc	1968-2006	23	678	22479	2982975	1.947	1.371	2.7	2.168	13.555	2.169	0.0002316	1.93058423	0.66628973
Infliximab	Spinal fracture	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	18	994	22484	2982659	1.03	0.693	1.486	1.07	0.082	1.07	0.775	1.13644833	0.0295588
Infliximab	Spinal fusion surgery	Spine and spinal cord therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	5	160	22497	2983493	1.315	0.624	2.512	1.658	1.238	1.658	0.266	1.4137211	0.27383667
Infliximab	Spinal laminectomy	Spine and spinal cord therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	1	87	22501	2983566	0.631	0.146	1.97	0.772	0.068	0.772	0.794	0.25905904	-0.4604494
Infliximab	Spinal myelogram abnormal	Central nervous system imaging procedures	Neurological and special sense investigations	Inv	1968-2006	1	95	22501	2983558	0.672	0.155	2.097	0.868	0.02	0.868	0.888	0.20788933	-0.3974969
Infliximab	Spinal operation	Spine and spinal cord therapeutic procedures	Nervous system, skull and spine therapeutic procedures	Surg	1968-2006	4	111	22498	2983542	1.43	0.624	2.906	2.011	1.931	2.011	0.165	1.41510297	0.35767444
Infliximab	Spinal osteoarthritis	Osteoarthropathies	Joint disorders	Musc	1968-2006	17	828	22485	2982825	1.302	0.865	1.896	1.392	1.806	1.392	0.179	1.28583925	0.26390154
Infliximab	Spindle cell sarcoma	Soft tissue sarcomas histology unspecified	Soft tissue sarcomas	Neopl	1968-2006	1	8	22501	2983645	1.159	0.268	3.626	5.486	3.161	5.486	0.075	0.89509832	0.14755756
Infliximab	Spirometry abnormal	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	15	22501	2983638	1.174	0.271	3.677	6.34	3.589	6.34	0.058	0.82595649	0.16041672
Infliximab	Spleen disorder	Spleen disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	18	472	22484	2983181	2.662	1.79	3.841	3.248	25.886	3.25	3.623e-7	2.01411559	0.97907772
Infliximab	Spleen malformation	Lymphatic system disorders congenital	Blood and lymphatic system disorders congenital	Cong	1968-2006	1	22	22501	2983631	1.177	0.272	3.683	6.018	3.635	6.018	0.057	0.75997701	0.16296883
Infliximab	Spleen scan abnormal	Bone marrow and immune tissue analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	4	22501	2983649	1.308	0.301	4.12	35.326	14.106	35.326	0.0001728	0.93614837	0.26849925
Infliximab	Spleen tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	8	2	22494	2983651	27.012	12.368	49.406	348.877	267.531	348.877	0	3.054941	3.29628121
Infliximab	Splenectomy	Lymphoid tissue therapeutic procedures	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	5	146	22497	2983507	1.636	0.776	3.126	2.288	3.424	2.288	0.064	1.48300747	0.49225424
Infliximab	Splenic abscess	Hepatobiliary and spleen infections	Infections - pathogen class unspecified	Infec	1968-2006	4	52	22498	2983601	2.307	1.006	4.703	5.044	11.938	5.045	0.001	1.8060072	0.83594798
Infliximab	Splenic cyst	Haematologic neoplasms NEC	Haematopoietic neoplasms (excl leukaemias and lymphomas)	Blood	1968-2006	1	20	22501	2983633	0.976	0.226	3.048	2.301	0.699	2.301	0.403	0.77852244	-0.0242927
Infliximab	Splenic haematoma	Abdominal injuries NEC	Injuries NEC	Inj&P	1968-2006	1	34	22501	2983619	0.868	0.201	2.71	1.596	0.208	1.596	0.649	0.65344776	-0.1415636
Infliximab	Splenic infarction	Spleen disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	9	222	22493	2983431	1.967	1.123	3.252	2.508	7.668	2.509	0.006	1.8625516	0.67650954
Infliximab	Splenic infection	Hepatobiliary and spleen infections	Infections - pathogen class unspecified	Infec	1968-2006	3	12	22499	2983641	2.538	0.974	5.752	12.039	25.211	12.048	5.138e-7	1.83563345	0.93137637
Infliximab	Splenic lesion	Spleen disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	1	29	22501	2983624	0.948	0.219	2.961	2.095	0.534	2.095	0.465	0.69688322	-0.0534008
Infliximab	Splenic rupture	Abdominal injuries NEC	Injuries NEC	Inj&P	1968-2006	3	217	22499	2983436	0.873	0.339	1.93	1.034	0.003	1.034	0.955	0.58482384	-0.1358197
Infliximab	Splenic vein thrombosis	Spleen disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	2	52	22500	2983601	1.347	0.436	3.379	2.799	2.092	2.799	0.148	1.0843418	0.2978799
Infliximab	Splenitis	Spleen disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	2	8	22500	2983645	1.92	0.618	4.874	11.775	15.538	11.775	0.00008087	1.46997828	0.65232519
Infliximab	Splenomegaly	Spleen disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	37	2175	22465	2981478	1.382	1.049	1.794	1.436	4.747	1.438	0.029	1.10202026	0.32353173
Infliximab	Spondylitis	Spondyloarthropathies	Joint disorders	Musc	1968-2006	8	130	22494	2983523	2.55	1.407	4.333	3.914	15.315	3.916	0.00009101	2.13543029	0.93609336
Infliximab	Spondyloarthropathy	Spondyloarthropathies	Joint disorders	Musc	1968-2006	5	16	22497	2983637	3.577	1.655	7.27	14.107	43.522	14.111	4.193e-11	2.36348522	1.27452446
Infliximab	Spondylolisthesis	Musculoskeletal and connective tissue disorders of spine congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	3	95	22499	2983558	1.563	0.607	3.458	2.771	3.117	2.773	0.077	1.19537591	0.44660705
Infliximab	Sporotrichosis	Sporothrix infections	Fungal infectious disorders	Infec	1968-2006	1	5	22501	2983648	1.287	0.296	4.049	17.221	10.766	17.221	0.001	0.92577585	0.25231393
Infliximab	Sports injury	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	29	22501	2983624	0.92	0.213	2.872	1.896	0.397	1.896	0.529	0.69688322	-0.0833816
Infliximab	Sputum abnormal	Respiratory tract and thoracic histopathology procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	2	274	22500	2983379	0.642	0.208	1.61	0.71	0.231	0.71	0.631	-0.0423411	-0.443167
Infliximab	Sputum culture positive	Microbiology and serology tests NEC	Microbiology and serology investigations	Inv	1968-2006	27	364	22475	2983289	3.22	2.33	4.361	3.937	52.814	3.942	3.667e-13	2.822999	1.16938136
Infliximab	Sputum discoloured	Coughing and associated symptoms	Respiratory disorders NEC	Resp	1968-2006	7	559	22495	2983094	0.833	0.442	1.46	0.884	0.102	0.884	0.749	0.60023664	-0.1827216
Infliximab	Sputum purulent	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	1	71	22501	2983582	0.664	0.154	2.072	0.849	0.027	0.849	0.869	0.36718681	-0.4094731
Infliximab	Sputum test	Respiratory tract and thoracic histopathology procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	5	22501	2983648	1.204	0.278	3.772	7.301	4.649	7.302	0.031	0.92577585	0.18564935
Infliximab	Squamous cell carcinoma	Neoplasms malignant site unspecified NEC	Miscellaneous and site unspecified neoplasms malignant and unspecified	Neopl	1968-2006	125	501	22377	2983152	11.896	10.158	13.824	16.905	1304.588	17.004	0	4.4588243	2.47620221
Infliximab	Squamous cell carcinoma of skin	Skin neoplasms malignant and unspecified (excl melanoma)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	38	122	22464	2983531	13.316	9.658	17.594	21.536	469.528	21.579	0	4.13853456	2.58896632
Infliximab	Squamous cell carcinoma of the cervix	Cervix neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	1	17	22501	2983636	1.052	0.243	3.288	3.036	1.353	3.037	0.245	0.80679534	0.05069311
Infliximab	Staphylococcal abscess	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	16	124	22486	2983529	4.85	3.163	7.247	7.913	82.091	7.918	1.3e-19	3.04238423	1.5789787
Infliximab	Staphylococcal bacteraemia	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	24	351	22478	2983302	3.042	2.158	4.192	3.703	42.918	3.706	5.708e-11	2.70419359	1.11251519
Infliximab	Staphylococcal impetigo	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	9	22501	2983644	1.211	0.28	3.794	7.552	4.9	7.553	0.027	0.88501574	0.19144646
Infliximab	Staphylococcal infection	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	300	5013	22202	2978640	3.399	3.089	3.734	3.652	533.523	3.692	0	2.87093539	1.22348127
Infliximab	Staphylococcal osteomyelitis	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	2	8	22500	2983645	1.916	0.617	4.862	11.76	15.324	11.761	0.00009054	1.46997828	0.65023968
Infliximab	Staphylococcal sepsis	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	86	1053	22416	2982600	4.598	3.84	5.471	5.296	269.805	5.317	0	3.17975622	1.52562143
Infliximab	Staring	Abnormal behaviour NEC	Psychiatric and behavioural symptoms NEC	Psych	1968-2006	1	451	22501	2983202	0.188	0.043	0.588	0.14	5.192	0.14	0.023	-1.1430939	-1.6713133
Infliximab	Stasis dermatitis	Dermatitis and eczema	Epidermal and dermal conditions	Skin	1968-2006	2	75	22500	2983578	1.058	0.343	2.653	1.611	0.442	1.611	0.506	0.91748111	0.05638033
Infliximab	Status asthmaticus	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	1	221	22501	2983432	0.344	0.079	1.075	0.296	1.633	0.296	0.201	-0.4233149	-1.0671136
Infliximab	Status epilepticus	Seizures and seizure disorders NEC	Seizures (incl subtypes)	Nerv	1968-2006	4	1465	22498	2982188	0.19	0.083	0.386	0.174	15.625	0.173	0.00007722	-1.2740908	-1.6607312
Infliximab	Steatorrhoea	Malabsorption syndromes	Malabsorption conditions	Gastr	1968-2006	1	1214	22501	2982439	0.134	0.031	0.42	0.096	8.392	0.096	0.004	-2.3469447	-2.0099155
Infliximab	Stem cell transplant	Haematological therapeutic procedures NEC	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	1	418	22501	2983235	0.175	0.04	0.548	0.129	5.782	0.129	0.016	-1.0593973	-1.7429693
Infliximab	Stenotrophomonas infection	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	6	106	22496	2983547	1.974	0.996	3.596	2.87	6.823	2.871	0.009	1.91804776	0.68006194
Infliximab	Stent occlusion	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	375	22501	2983278	0.204	0.047	0.638	0.155	4.556	0.155	0.033	-0.9425052	-1.5896353
Infliximab	Stent placement	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	9	336	22493	2983317	1.304	0.744	2.156	1.474	1.327	1.474	0.249	1.46998649	0.26543646
Infliximab	Sternal fracture	Thoracic cage fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	1	50	22501	2983603	0.775	0.179	2.418	1.185	0.027	1.185	0.869	0.52263848	-0.2548922
Infliximab	Stevens-Johnson syndrome	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	14	8534	22488	2975119	0.167	0.106	0.252	0.161	61.796	0.16	3.81e-15	-2.1301022	-1.7897615
Infliximab	Stillbirth	Stillbirth and foetal death	Abortions and stillbirth	Preg	1968-2006	1	1357	22501	2982296	0.123	0.028	0.384	0.086	9.537	0.086	0.002	-2.4924125	-2.0955709
Infliximab	Stitch abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	12	22501	2983641	1.192	0.275	3.734	6.167	4.177	6.167	0.041	0.85518395	0.17563257
Infliximab	Stomach discomfort	Gastrointestinal signs and symptoms NEC	Gastrointestinal signs and symptoms	Gastr	1968-2006	6	3201	22496	2980452	0.114	0.058	0.208	0.105	45.69	0.104	1.385e-11	-1.8491991	-2.1715568
Infliximab	Stomatitis	Stomatitis and ulceration	Oral soft tissue conditions	Gastr	1968-2006	27	9869	22475	2973784	0.481	0.348	0.651	0.475	15.494	0.475	0.00008278	-1.4385167	-0.731888
Infliximab	Strabismus congenital	Ocular disorders congenital NEC	Eye disorders congenital	Cong	1968-2006	1	9	22501	2983644	1.18	0.273	3.695	5.784	3.782	5.784	0.052	0.88501574	0.16551444
Infliximab	Streptococcal abscess	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	3	12	22499	2983641	2.472	0.952	5.568	11.679	22.302	11.679	0.00000233	1.83563345	0.90502754
Infliximab	Streptococcal bacteraemia	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	9	84	22493	2983569	3.349	1.908	5.558	5.726	31.075	5.728	2.482e-8	2.54879566	1.20866179
Infliximab	Streptococcal impetigo	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	1	22501	2983652	1.347	0.308	4.264	190.333	26.626	190.333	2.47e-7	0.967721	0.2978799
Infliximab	Streptococcal infection	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	62	1046	22440	2982607	3.395	2.746	4.162	3.836	118.413	3.846	1.408e-27	2.74967586	1.22230376
Infliximab	Streptococcal sepsis	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	33	270	22469	2983383	5.24	3.902	6.934	7.015	147.859	7.026	5.092e-34	3.36805917	1.6563215
Infliximab	Streptococcal serology	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	4	22501	2983649	1.24	0.286	3.89	10.336	6.503	10.336	0.011	0.93614837	0.21511138
Infliximab	Streptococcal serology positive	Bacteria identification and serology (excl mycobacteria)	Microbiology and serology investigations	Inv	1968-2006	1	57	22501	2983596	0.781	0.181	2.439	1.209	0.034	1.209	0.853	0.46893872	-0.2471801
Infliximab	Stress	Anxiety symptoms	Anxiety disorders and symptoms	Psych	1968-2006	16	3178	22486	2980475	0.341	0.224	0.502	0.332	21.24	0.332	4.053e-6	-0.563455	-1.0758728
Infliximab	Stress fracture	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	6	183	22496	2983470	1.471	0.742	2.678	1.849	2.237	1.849	0.135	1.52456828	0.38594244
Infliximab	Stress incontinence				1968-2006	1	152	22501	2983501	0.499	0.115	1.557	0.509	0.457	0.509	0.499	-0.1120602	-0.6951492
Infliximab	Stridor	Laryngeal spasm, oedema and obstruction	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	8	1415	22494	2982238	0.669	0.369	1.136	0.688	1.137	0.688	0.286	-0.3840536	-0.4019712
Infliximab	Strongyloidiasis	Nematode infections	Helminthic disorders	Infec	1968-2006	2	54	22500	2983599	1.264	0.41	3.171	2.308	1.47	2.308	0.225	1.06904131	0.2342813
Infliximab	Stupor	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	8	6672	22494	2976981	0.467	0.258	0.792	0.463	4.954	0.463	0.026	-2.5166212	-0.761426
Infliximab	Subacute endocarditis	Cardiac infections	Infections - pathogen class unspecified	Infec	1968-2006	3	21	22499	2983632	2.329	0.9	5.204	8.17	16.783	8.171	0.00004192	1.75079308	0.84543899
Infliximab	Subarachnoid haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	23	1770	22479	2981883	1.011	0.712	1.401	1.04	0.034	1.04	0.853	0.72315204	0.01093994
Infliximab	Subclavian artery stenosis	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	38	22501	2983615	0.888	0.206	2.774	1.7	0.272	1.7	0.602	0.61961696	-0.1187835
Infliximab	Subclavian artery thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	38	22501	2983615	0.944	0.218	2.946	2.045	0.508	2.045	0.476	0.61961696	-0.0576291
Infliximab	Subclavian vein thrombosis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	2	155	22500	2983498	0.604	0.196	1.514	0.655	0.366	0.655	0.545	0.45290425	-0.5041811
Infliximab	Subcorneal pustular dermatosis	Pustular conditions	Epidermal and dermal conditions	Skin	1968-2006	2	8	22500	2983645	1.888	0.609	4.783	10.104	13.863	10.106	0.0001967	1.46997828	0.63551807
Infliximab	Subcutaneous abscess	Skin structures and soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	17	300	22485	2983353	2.893	1.923	4.216	3.654	30.083	3.657	4.139e-8	2.40497357	1.06229403
Infliximab	Subcutaneous emphysema	Skin and subcutaneous conditions NEC	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	11	133	22491	2983520	3.362	2.021	5.336	5.362	33.301	5.364	7.894e-9	2.51894105	1.21253603
Infliximab	Subcutaneous nodule	Skin and subcutaneous conditions NEC	Skin and subcutaneous tissue disorders NEC	Skin	1968-2006	4	400	22498	2983253	1.017	0.444	2.066	1.209	0.143	1.209	0.705	0.30224193	0.01685712
Infliximab	Subdural empyema	Central nervous system and spinal infections	Infections - pathogen class unspecified	Infec	1968-2006	1	11	22501	2983642	1.162	0.269	3.638	5.173	3.237	5.173	0.072	0.86505951	0.15014266
Infliximab	Subdural haematoma	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	7	1817	22495	2981836	0.344	0.182	0.602	0.333	9.309	0.332	0.002	-0.8848617	-1.0671136
Infliximab	Subdural haemorrhage	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	2	125	22500	2983528	0.849	0.275	2.128	1.085	0.013	1.085	0.908	0.61011908	-0.1636961
Infliximab	Subendocardial ischaemia	Ischaemic coronary artery disorders	Coronary artery disorders	Card	1968-2006	1	18	22501	2983635	1.085	0.251	3.392	3.502	1.749	3.502	0.186	0.79730935	0.08157999
Infliximab	Subileus	Gastrointestinal stenosis and obstruction NEC	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	4	181	22498	2983472	0.975	0.426	1.98	1.145	0.07	1.145	0.791	1.05714325	-0.0253178
Infliximab	Submandibular mass	Mass conditions NEC	Tissue disorders NEC	Genrl	1968-2006	4	10	22498	2983643	3.852	1.519	13.629	30.838	65.224	30.838	6.684e-16	2.16730378	1.34859249
Infliximab	Submaxillary gland enlargement	Salivary gland enlargements	Salivary gland conditions	Gastr	1968-2006	1	7	22501	2983646	1.194	0.276	3.741	6.151	4.276	6.151	0.039	0.90525186	0.17730901
Infliximab	Sudden cardiac death	Death and sudden death	Fatal outcomes	Genrl	1968-2006	7	408	22495	2983245	0.907	0.481	1.589	0.977	0.004	0.977	0.951	0.95108789	-0.0976128
Infliximab	Sudden death	Death and sudden death	Fatal outcomes	Genrl	1968-2006	37	4174	22465	2979479	0.737	0.559	0.956	0.739	3.37	0.738	0.066	0.21178541	-0.3051674
Infliximab	Sudden hearing loss	Hearing losses	Hearing disorders	Ear	1968-2006	6	125	22496	2983528	1.788	0.902	3.256	2.432	4.886	2.433	0.027	1.81053416	0.58109768
Infliximab	Suffocation feeling	Respiratory signs and symptoms NEC	Respiratory disorders NEC	Resp	1968-2006	4	220	22498	2983433	0.935	0.408	1.9	1.082	0.024	1.082	0.877	0.89052163	-0.0672087
Infliximab	Suicidal ideation	Suicidal and self-injurious behaviour	Suicidal and self-injurious behaviours NEC	Psych	1968-2006	25	9273	22477	2974380	0.153	0.109	0.209	0.148	123.785	0.147	9.387e-29	-1.4564532	-1.8773174
Infliximab	Suicide attempt	Suicidal and self-injurious behaviour	Suicidal and self-injurious behaviours NEC	Psych	1968-2006	15	14192	22487	2969461	0.113	0.073	0.168	0.108	111.069	0.107	5.716e-26	-2.7638119	-2.1803675
Infliximab	Sunburn	Radiation injuries	Injuries by physical agents	Inj&P	1968-2006	5	374	22497	2983279	0.843	0.4	1.609	0.921	0.033	0.921	0.856	0.63398905	-0.1707883
Infliximab	Superficial injury of eye	Eye injuries NEC	Injuries NEC	Inj&P	1968-2006	1	22	22501	2983631	1.011	0.234	3.158	2.692	0.955	2.692	0.328	0.75997701	0.01093994
Infliximab	Superficial spreading melanoma stage unspecified	Skin melanomas (excl ocular)	Skin neoplasms malignant and unspecified	Neopl	1968-2006	2	7	22500	2983646	2.142	0.677	5.605	26.658	35.301	26.658	2.825e-9	1.48006086	0.76173997
Infliximab	Superinfection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	22	923	22480	2982730	2.871	2.005	4.009	3.458	35.474	3.462	2.585e-9	1.49906065	1.0546604
Infliximab	Superinfection lung	Lower respiratory tract and lung infections	Infections - pathogen class unspecified	Infec	1968-2006	1	57	22501	2983596	0.703	0.163	2.196	0.954	0.002	0.954	0.962	0.46893872	-0.3523984
Infliximab	Superior sagittal sinus thrombosis	Cerebrovascular venous and sinus thrombosis	Central nervous system vascular disorders	Nerv	1968-2006	4	131	22498	2983522	1.436	0.627	2.917	2.01	1.961	2.01	0.161	1.30345829	0.36186147
Infliximab	Superior vena caval occlusion	Site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	3	128	22499	2983525	1.082	0.42	2.392	1.414	0.365	1.414	0.546	1.00317851	0.07881118
Infliximab	Suprapubic pain	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	1	55	22501	2983598	0.72	0.167	2.247	1.002	0	1.002	0.999	0.48407867	-0.3285041
Infliximab	Supraventricular extrasystoles	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	19	1287	22483	2982366	1.251	0.85	1.788	1.323	1.449	1.323	0.229	0.8807415	0.22394323
Infliximab	Supraventricular tachycardia	Supraventricular arrhythmias	Cardiac arrhythmias	Card	1968-2006	37	3338	22465	2980315	1.242	0.942	1.612	1.282	2.208	1.283	0.137	0.52051828	0.21672298
Infliximab	Surgery	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	75	2691	22427	2980962	2.247	1.853	2.705	2.395	57.017	2.401	4.321e-14	1.79587246	0.80959599
Infliximab	Surgical procedure repeated	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	10	452	22492	2983201	1.096	0.644	1.77	1.187	0.284	1.187	0.594	1.29190784	0.09166719
Infliximab	Suture rupture	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	45	22500	2983608	1.376	0.446	3.452	2.887	2.342	2.888	0.126	1.13920853	0.31918074
Infliximab	Swelling	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	79	5931	22423	2977722	0.903	0.748	1.082	0.907	0.747	0.906	0.387	0.78507331	-0.1020327
Infliximab	Swelling face	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	49	4326	22453	2979327	0.621	0.489	0.78	0.617	11.504	0.616	0.001	0.55418411	-0.4764242
Infliximab	Swollen tongue	Tongue signs and symptoms	Tongue conditions	Gastr	1968-2006	26	1917	22476	2981736	0.703	0.506	0.957	0.705	3.138	0.705	0.076	0.78483934	-0.3523984
Infliximab	Syncope	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	154	29566	22348	2954087	0.755	0.66	0.86	0.752	12.518	0.75	0.0004031	-0.5529763	-0.2810375
Infliximab	Syncope vasovagal	Disturbances in consciousness NEC	Neurological disorders NEC	Nerv	1968-2006	26	1086	22476	2982567	1.503	1.081	2.047	1.597	5.581	1.598	0.018	1.52262555	0.40746311
Infliximab	Synovectomy	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	5	25	22497	2983628	3.094	1.457	6.001	9.412	27.806	9.416	1.341e-7	2.28184608	1.12946475
Infliximab	Synovial cyst	Synovial disorders	Synovial and bursal disorders	Musc	1968-2006	11	142	22491	2983511	3.417	2.054	5.424	5.281	34.467	5.284	4.335e-9	2.47290495	1.22876297
Infliximab	Synovial disorder	Synovial disorders	Synovial and bursal disorders	Musc	1968-2006	4	51	22498	2983602	2.391	1.042	4.88	5.561	13.581	5.562	0.0002285	1.81363716	0.87171169
Infliximab	Synovial fluid crystal present	Musculoskeletal and soft tissue histopathology procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	1	2	22501	2983651	1.318	0.303	4.159	37.244	16.456	37.244	0.00004979	0.95711984	0.27611544
Infliximab	Synovial fluid white blood cells positive	Musculoskeletal and soft tissue histopathology procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	1	6	22501	2983647	1.236	0.285	3.877	10.084	6.234	10.084	0.013	0.91547736	0.21188036
Infliximab	Synovial rupture	Limb injuries NEC (incl traumatic amputation)	Bone and joint injuries	Inj&P	1968-2006	1	8	22501	2983645	1.219	0.281	3.82	7.419	5.297	7.419	0.021	0.89509832	0.19803085
Infliximab	Synovitis	Synovial disorders	Synovial and bursal disorders	Musc	1968-2006	84	439	22418	2983214	10.896	8.876	13.197	15.398	810.255	15.459	0	4.10119424	2.38839575
Infliximab	Syphilis	Treponema infections	Bacterial infectious disorders	Infec	1968-2006	1	41	22501	2983612	0.97	0.224	3.029	2.209	0.655	2.209	0.418	0.59475445	-0.0304592
Infliximab	Syringomyelia	Spinal cord and nerve root disorders NEC	Spinal cord and nerve root disorders	Nerv	1968-2006	2	37	22500	2983616	1.378	0.447	3.458	2.981	2.38	2.981	0.123	1.20457957	0.32063317
Infliximab	Systemic candida	Candida infections	Fungal infectious disorders	Infec	1968-2006	16	215	22486	2983438	4.031	2.641	5.957	5.82	57.577	5.823	3.25e-14	2.62808851	1.39401448
Infliximab	Systemic inflammatory response syndrome	Inflammations	General system disorders NEC	Genrl	1968-2006	12	292	22490	2983361	1.684	1.035	2.619	1.937	5.258	1.938	0.022	1.97772785	0.52117192
Infliximab	Systemic lupus erythematosus	Lupus erythematosus (incl subtypes)	Connective tissue disorders (excl congenital)	Musc	1968-2006	405	4060	22097	2979593	10.073	9.256	10.945	13.229	3448.028	13.506	0	3.54727247	2.30985858
Infliximab	Systemic lupus erythematosus rash	Connective tissue disorders	Epidermal and dermal conditions	Skin	1968-2006	22	375	22480	2983278	5.176	3.598	7.306	7.737	109.795	7.745	1.086e-25	2.52279434	1.64403256
Infliximab	Systemic mastocytosis	Haematological disorders	Haematological disorders NEC	Blood	1968-2006	1	4	22501	2983649	1.254	0.289	3.937	10.122	7.486	10.122	0.006	0.93614837	0.22633844
Infliximab	Systemic mycosis	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	6	115	22496	2983538	2.29	1.155	4.174	3.71	10.743	3.71	0.001	1.86612061	0.82855182
Infliximab	Systemic sclerosis	Connective tissue disorders (excl LE)	Connective tissue disorders (excl congenital)	Musc	1968-2006	1	62	22501	2983591	0.734	0.17	2.292	1.045	0.002	1.045	0.965	0.43176963	-0.3092463
Infliximab	Systolic hypertension	Vascular hypertensive disorders NEC	Vascular hypertensive disorders	Vasc	1968-2006	1	56	22501	2983597	0.715	0.165	2.233	0.988	0	0.988	0.991	0.47648884	-0.3354727
Infliximab	T-cell lymphoma	Anaplastic large cell lymphomas T- and null-cell types	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	39	106	22463	2983547	16.166	12.202	20.984	24.421	588.347	24.484	0	4.25072548	2.78291027
Infliximab	T-cell lymphoma recurrent	Anaplastic large cell lymphomas T- and null-cell types	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	1	5	22501	2983648	1.255	0.29	3.939	10.873	7.491	10.873	0.006	0.92577585	0.22713557
Infliximab	T-cell lymphoma stage IV	Anaplastic large cell lymphomas T- and null-cell types	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	5	4	22497	2983649	15.014	2.899	49.973	67.774	174.706	67.774	6.942e-40	2.48006096	2.7089831
Infliximab	T-cell prolymphocytic leukaemia	Leukaemias chronic T-cell	Leukaemias	Neopl	1968-2006	1	1	22501	2983652	1.36	0.311	4.313	50.511	34.693	50.511	3.86e-9	0.967721	0.3074847
Infliximab	T-cell unclassifiable lymphoma high grade	T-cell unclassifiable lymphomas	Lymphomas non-Hodgkins T-cell	Neopl	1968-2006	1	0	22501	2983653	1.391	0.316	4.44	1094.202	126.482	1101.968	2.411e-29	0.97840063	0.33002291
Infliximab	Tachyarrhythmia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	9	422	22493	2983231	1.034	0.59	1.71	1.118	0.11	1.118	0.741	1.23153414	0.03343478
Infliximab	Tachycardia	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	318	36289	22184	2947364	1.517	1.382	1.662	1.54	58.984	1.55	1.59e-14	0.18555435	0.4167347
Infliximab	Tachycardia paroxysmal	Rate and rhythm disorders NEC	Cardiac arrhythmias	Card	1968-2006	2	64	22500	2983589	1.196	0.387	2.998	2.056	1.054	2.056	0.305	0.99488192	0.17898266
Infliximab	Tachyphylaxis	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	3	52	22499	2983601	1.862	0.723	4.123	4.094	6.475	4.096	0.011	1.49170892	0.62165118
Infliximab	Tachypnoea	Breathing abnormalities	Respiratory disorders NEC	Resp	1968-2006	42	2328	22460	2981325	1.318	1.018	1.685	1.36	3.892	1.361	0.049	1.18623615	0.27611544
Infliximab	Takayasus arteritis	Arterial inflammations	Vascular inflammations	Vasc	1968-2006	2	15	22500	2983638	1.908	0.614	4.839	10.801	14.746	10.801	0.000123	1.40130667	0.64605557
Infliximab	Talipes	Musculoskeletal and connective tissue disorders of limbs congenital	Musculoskeletal and connective tissue disorders congenital	Cong	1968-2006	2	412	22500	2983241	0.373	0.121	0.934	0.35	2.385	0.35	0.122	-0.4613188	-0.9861769
Infliximab	Tardive dyskinesia	Dyskinesias and movement disorders NEC	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	1	1976	22501	2981677	0.077	0.018	0.241	0.052	16.966	0.052	0.00003806	-2.9935058	-2.5639499
Infliximab	Tearfulness	Mood alterations with depressive symptoms	Depressed mood disorders and disturbances	Psych	1968-2006	6	444	22496	2983209	0.707	0.357	1.287	0.737	0.551	0.737	0.458	0.66919954	-0.3467246
Infliximab	Telangiectasia	Telangiectasia and related conditions	Skin vascular abnormalities	Skin	1968-2006	1	149	22501	2983504	0.453	0.105	1.414	0.438	0.701	0.438	0.403	-0.0968774	-0.7918632
Infliximab	Temperature intolerance	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	5	348	22497	2983305	0.809	0.384	1.545	0.876	0.086	0.876	0.77	0.70909947	-0.2119564
Infliximab	Temperature regulation disorder	Body temperature altered	Body temperature conditions	Genrl	1968-2006	1	129	22501	2983524	0.47	0.109	1.468	0.468	0.603	0.468	0.438	0.0086413	-0.7550226
Infliximab	Temporal arteritis	Arterial inflammations	Vascular inflammations	Vasc	1968-2006	2	223	22500	2983430	0.59	0.191	1.479	0.628	0.424	0.628	0.515	0.14952614	-0.5276327
Infliximab	Temporal lobe epilepsy	Partial complex seizures	Seizures (incl subtypes)	Nerv	1968-2006	1	67	22501	2983586	0.686	0.159	2.14	0.903	0.01	0.903	0.921	0.39553403	-0.3768777
Infliximab	Temporomandibular joint syndrome	Joint related disorders NEC	Joint disorders	Musc	1968-2006	2	121	22500	2983532	0.904	0.293	2.265	1.202	0.068	1.202	0.795	0.63243733	-0.1009259
Infliximab	Tenderness	Pain and discomfort NEC	General system disorders NEC	Genrl	1968-2006	22	1439	22480	2982214	1.118	0.781	1.562	1.162	0.484	1.162	0.487	0.93477476	0.11154137
Infliximab	Tendon disorder	Tendon disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	7	1476	22495	2982177	0.49	0.26	0.859	0.489	3.717	0.489	0.054	-0.6085727	-0.7133499
Infliximab	Tendon operation	Tendon therapeutic procedures	Soft tissue therapeutic procedures	Surg	1968-2006	2	9	22500	2983644	1.852	0.598	4.685	10.624	12.279	10.627	0.0004582	1.45996566	0.61626614
Infliximab	Tendon repair				1968-2006	1	13	22501	2983640	1.252	0.289	3.929	12.076	7.265	12.076	0.007	0.84537553	0.22474227
Infliximab	Tendon rupture	Muscle, tendon and ligament injuries	Injuries NEC	Inj&P	1968-2006	19	1174	22483	2982479	1.14	0.775	1.629	1.194	0.576	1.194	0.448	0.99873108	0.13102826
Infliximab	Tendon sheath incision	Tendon therapeutic procedures	Soft tissue therapeutic procedures	Surg	1968-2006	1	6	22501	2983647	1.223	0.282	3.836	8.954	5.528	8.954	0.019	0.91547736	0.20130686
Infliximab	Tendon transfer	Tendon therapeutic procedures	Soft tissue therapeutic procedures	Surg	1968-2006	1	2	22501	2983651	1.28	0.295	4.026	19.76	10.074	19.76	0.002	0.95711984	0.24686008
Infliximab	Tendonitis	Tendon disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	11	1456	22491	2982197	0.535	0.322	0.846	0.534	4.427	0.534	0.035	-0.0092507	-0.6254885
Infliximab	Tenosynovitis	Synovial disorders	Synovial and bursal disorders	Musc	1968-2006	11	904	22491	2982749	2.381	1.433	3.77	3.12	14.536	3.121	0.0001375	0.60116669	0.86752057
Infliximab	Tenosynovitis stenosans	Synovial disorders	Synovial and bursal disorders	Musc	1968-2006	1	14	22501	2983639	1.145	0.265	3.582	4.721	2.814	4.722	0.093	0.83563334	0.13540464
Infliximab	Tension headache	Headaches NEC	Headaches	Nerv	1968-2006	3	210	22499	2983443	0.763	0.296	1.687	0.858	0.068	0.858	0.794	0.61367424	-0.2704972
Infliximab	Testicular disorder	Testicular and epididymal disorders NEC	Testicular and epididymal disorders	Repro	1968-2006	2	825	22500	2982828	0.648	0.21	1.623	0.719	0.214	0.719	0.643	-1.2723372	-0.4338646
Infliximab	Testicular germ cell cancer	Testicular neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	11	22501	2983642	1.14	0.264	3.568	4.825	2.719	4.828	0.099	0.86505951	0.13102826
Infliximab	Testicular mass	Testicular and epididymal disorders NEC	Testicular and epididymal disorders	Repro	1968-2006	1	8	22501	2983645	1.242	0.286	3.896	10.285	6.555	10.289	0.01	0.89509832	0.21672298
Infliximab	Testicular neoplasm	Reproductive neoplasms male unspecified malignancy	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	27	22501	2983626	1.016	0.235	3.174	2.688	0.992	2.689	0.319	0.71463025	0.01587335
Infliximab	Testicular pain	Testicular and epididymal disorders NEC	Testicular and epididymal disorders	Repro	1968-2006	1	433	22501	2983220	0.226	0.052	0.705	0.178	3.849	0.178	0.05	-1.0980439	-1.4872203
Infliximab	Testicular seminoma (pure) stage II	Testicular neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.4	0.317	4.479	1096.877	159.701	1104.598	1.315e-36	0.97840063	0.33647224
Infliximab	Testis cancer	Testicular neoplasms malignant	Reproductive neoplasms male malignant and unspecified	Neopl	1968-2006	8	75	22494	2983578	3.97	2.17	6.899	8.631	46.021	8.642	1.17e-11	2.46191313	1.37876609
Infliximab	Tetanus	Clostridia infections	Bacterial infectious disorders	Infec	1968-2006	1	18	22501	2983635	1.121	0.259	3.505	4.556	2.319	4.556	0.128	0.79730935	0.11422114
Infliximab	Tetany	Calcium metabolism disorders	Bone, calcium, magnesium and phosphorus metabolism disorders	Metab	1968-2006	4	577	22498	2983076	0.779	0.34	1.582	0.854	0.099	0.854	0.753	-0.1084495	-0.2497442
Infliximab	Thalamus haemorrhage	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	2	56	22500	2983597	1.235	0.4	3.097	2.241	1.28	2.241	0.258	1.05390137	0.21107097
Infliximab	Therapeutic agent toxicity	Poisoning and toxicity	Chemical injury and poisoning	Inj&P	1968-2006	2	3879	22500	2979774	0.099	0.032	0.248	0.08	20.859	0.08	4.944e-6	-3.337069	-2.3126354
Infliximab	Therapeutic product ineffective	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	2	109	22500	2983544	0.763	0.247	1.913	0.916	0.015	0.916	0.903	0.7015412	-0.2704972
Infliximab	Therapeutic response decreased	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	141	2993	22361	2980660	2.511	2.182	2.877	2.67	137.16	2.681	1.113e-31	2.52516703	0.92068108
Infliximab	Therapeutic response unexpected	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	7	3050	22495	2980603	0.332	0.176	0.582	0.319	9.967	0.319	0.002	-1.5902014	-1.1026203
Infliximab	Therapy non-responder	Therapeutic and nontherapeutic responses	Therapeutic and nontherapeutic effects (excl toxicity)	Genrl	1968-2006	55	2547	22447	2981106	1.38	1.102	1.712	1.418	6.638	1.42	0.01	1.43936667	0.3220835
Infliximab	Therapy regimen changed	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	1	46	22501	2983607	0.839	0.194	2.618	1.432	0.131	1.432	0.718	0.5542459	-0.1755446
Infliximab	Thermal burn	Thermal burns	Injuries by physical agents	Inj&P	1968-2006	2	714	22500	2982939	0.198	0.064	0.496	0.171	8.085	0.171	0.004	-1.0951306	-1.6194882
Infliximab	Thinking abnormal	Thinking disturbances	Disturbances in thinking and perception	Psych	1968-2006	10	11028	22492	2972625	0.21	0.123	0.339	0.201	31.676	0.2	1.821e-8	-2.9425741	-1.5606477
Infliximab	Thirst	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	6	2804	22496	2980849	0.259	0.131	0.473	0.247	13.744	0.247	0.0002095	-1.6664811	-1.3509272
Infliximab	Thoracic outlet syndrome	Peripheral neuropathies NEC	Peripheral neuropathies	Nerv	1968-2006	2	28	22500	2983625	1.561	0.506	3.923	4.508	4.578	4.509	0.032	1.28184581	0.44532664
Infliximab	Thoracic vertebral fracture	Spinal fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	3	138	22499	2983515	0.955	0.371	2.111	1.179	0.077	1.179	0.781	0.94965418	-0.0460439
Infliximab	Throat cancer	Respiratory tract and pleural neoplasms malignant cell type unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	8	115	22494	2983538	2.805	1.547	4.771	4.582	19.611	4.584	0.00000949	2.21740124	1.03140354
Infliximab	Throat irritation	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	35	3069	22467	2980584	0.839	0.632	1.097	0.847	0.957	0.846	0.328	0.55861685	-0.1755446
Infliximab	Throat lesion	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	1	39	22501	2983614	0.773	0.179	2.414	1.178	0.026	1.178	0.872	0.61128176	-0.2574762
Infliximab	Throat tightness	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	118	3000	22384	2980653	2.373	2.035	2.753	2.501	100.731	2.51	1.053e-23	2.27731633	0.86415498
Infliximab	Thrombin time shortened	Coagulation and bleeding analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	1	6	22501	2983647	1.241	0.286	3.895	11.447	6.605	11.447	0.01	0.91547736	0.21591751
Infliximab	Thrombocythaemia	Secondary thrombocythaemias	Platelet disorders	Blood	1968-2006	30	1951	22472	2981702	1.814	1.335	2.42	1.955	13.328	1.957	0.0002615	0.95797009	0.59553435
Infliximab	Thrombocytopenia	Thrombocytopenias	Platelet disorders	Blood	1968-2006	151	36157	22351	2947496	0.623	0.544	0.71	0.618	35.56	0.616	2.473e-9	-0.872077	-0.4732088
Infliximab	Thrombolysis	Haematological therapeutic procedures NEC	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	1	26	22501	2983627	1.055	0.244	3.297	3.259	1.374	3.259	0.241	0.72358631	0.05354077
Infliximab	Thrombophlebitis	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	10	357	22492	2983296	1.479	0.869	2.389	1.695	2.748	1.695	0.097	1.54264125	0.39136618
Infliximab	Thrombophlebitis septic	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	2	22	22500	2983631	1.764	0.57	4.448	6.906	8.979	6.907	0.003	1.33575551	0.56758396
Infliximab	Thrombophlebitis superficial	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	8	283	22494	2983370	1.515	0.836	2.573	1.808	2.786	1.808	0.095	1.49072689	0.41541544
Infliximab	Thrombosis	Non-site specific embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	70	9528	22432	2974125	0.458	0.375	0.555	0.452	46.561	0.45	8.879e-12	-0.0524442	-0.7808861
Infliximab	Thrombotic microangiopathy	Coagulopathies	Coagulopathies and bleeding diatheses (excl thrombocytopenic)	Blood	1968-2006	1	616	22501	2983037	0.157	0.036	0.492	0.116	6.747	0.116	0.009	-1.501305	-1.8515095
Infliximab	Thrombotic stroke	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	4	165	22498	2983488	1.313	0.573	2.668	1.753	1.241	1.753	0.265	1.13148638	0.2723146
Infliximab	Thrombotic thrombocytopenic purpura	Thrombocytopenias	Platelet disorders	Blood	1968-2006	10	1315	22492	2982338	0.716	0.421	1.157	0.734	0.947	0.733	0.33	-0.0006845	-0.3340751
Infliximab	Thymoma	Mediastinal neoplasms malignancy unspecified NEC	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	2	22	22500	2983631	1.732	0.56	4.363	6.916	8.081	6.916	0.004	1.33575551	0.54927681
Infliximab	Thymoma malignant	Mediastinal neoplasms malignant	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	1	12	22501	2983641	1.161	0.268	3.633	5.823	3.223	5.823	0.073	0.85518395	0.1492817
Infliximab	Thymus disorder	Thymus disorders	Spleen, lymphatic and reticuloendothelial system disorders	Blood	1968-2006	1	52	22501	2983601	0.802	0.185	2.502	1.278	0.061	1.278	0.805	0.50709068	-0.2206467
Infliximab	Thyroid adenoma	Thyroid neoplasms benign	Endocrine neoplasms benign	Neopl	1968-2006	1	82	22501	2983571	0.854	0.198	2.667	1.516	0.169	1.516	0.681	0.29198681	-0.1578241
Infliximab	Thyroid cancer	Thyroid neoplasms malignant	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	5	29	22497	2983624	2.842	1.343	5.47	7.068	21.328	7.078	0.00000387	2.24699378	1.04450803
Infliximab	Thyroid cancer metastatic	Thyroid neoplasms malignant	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	1	11	22501	2983642	1.159	0.268	3.628	5.525	3.171	5.526	0.075	0.86505951	0.14755756
Infliximab	Thyroid cyst	Thyroid neoplasms	Thyroid gland disorders	Endo	1968-2006	3	60	22499	2983593	1.615	0.627	3.573	3.016	3.617	3.016	0.057	1.43176995	0.47933496
Infliximab	Thyroid disorder	Thyroid disorders NEC	Thyroid gland disorders	Endo	1968-2006	7	1547	22495	2982106	0.481	0.255	0.842	0.476	3.966	0.475	0.046	-0.6706175	-0.731888
Infliximab	Thyroid gland abscess	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	1	3	22501	2983650	1.282	0.295	4.031	17.184	10.146	17.184	0.001	0.946596	0.24842136
Infliximab	Thyroid gland cancer				1968-2006	17	244	22485	2983409	3.782	2.511	5.52	5.398	52.775	5.403	3.741e-13	2.59645885	1.33025297
Infliximab	Thyroid mass	Thyroid disorders NEC	Thyroid gland disorders	Endo	1968-2006	1	40	22501	2983613	0.875	0.202	2.73	1.633	0.227	1.633	0.634	0.60299444	-0.1335314
Infliximab	Thyroid neoplasm	Endocrine neoplasms malignant and unspecified NEC	Endocrine neoplasms malignant and unspecified	Neopl	1968-2006	14	336	22488	2983317	2.215	1.412	3.343	2.716	13.821	2.717	0.0002011	2.03995434	0.7952524
Infliximab	Thyroidectomy	Thyroid therapeutic procedures	Endocrine gland therapeutic procedures	Surg	1968-2006	4	74	22498	2983579	1.985	0.866	4.038	3.684	7.097	3.685	0.008	1.64761223	0.68561891
Infliximab	Thyroiditis	Acute and chronic thyroiditis	Thyroid gland disorders	Endo	1968-2006	12	391	22490	2983262	2.783	1.711	4.33	3.724	22.412	3.727	0.0000022	1.68344306	1.02352948
Infliximab	Thyroiditis acute	Acute and chronic thyroiditis	Thyroid gland disorders	Endo	1968-2006	1	12	22501	2983641	1.152	0.266	3.603	4.833	2.97	4.833	0.085	0.85518395	0.14149956
Infliximab	Thyroiditis subacute	Acute and chronic thyroiditis	Thyroid gland disorders	Endo	1968-2006	5	12	22497	2983641	4.394	1.88	13.941	24.38	69.455	24.39	7.82e-17	2.40130684	1.48023997
Infliximab	Thyrotoxic crisis	Thyroid hyperfunction disorders	Thyroid gland disorders	Endo	1968-2006	2	74	22500	2983579	1.06	0.344	2.657	1.615	0.448	1.615	0.503	0.92434846	0.05826891
Infliximab	Thyroxine decreased	Thyroid analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	146	22501	2983507	0.496	0.115	1.549	0.505	0.469	0.505	0.493	-0.0815331	-0.7011794
Infliximab	Thyroxine free increased	Thyroid analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	44	22501	2983609	0.76	0.176	2.371	1.13	0.014	1.13	0.904	0.5703131	-0.2744368
Infliximab	Thyroxine increased	Thyroid analyses	Endocrine investigations (incl sex hormones)	Inv	1968-2006	1	147	22501	2983506	0.59	0.136	1.841	0.676	0.148	0.676	0.7	-0.086666	-0.5276327
Infliximab	Tibia fracture	Lower limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	11	228	22491	2983425	2.096	1.262	3.319	2.631	10.287	2.632	0.001	2.09426928	0.74003077
Infliximab	Tic	Tic disorders	Changes in physical activity	Psych	1968-2006	2	807	22500	2982846	0.182	0.059	0.456	0.155	9.169	0.155	0.002	-1.2450382	-1.7037486
Infliximab	Tinea blanca	Tinea infections	Fungal infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.29	0.297	4.061	17.295	11.301	17.295	0.001	0.95711984	0.25464222
Infliximab	Tinea infection	Tinea infections	Fungal infectious disorders	Infec	1968-2006	4	61	22498	2983592	2.064	0.901	4.201	4.029	8.143	4.03	0.004	1.73909459	0.72464585
Infliximab	Tinea pedis	Tinea infections	Fungal infectious disorders	Infec	1968-2006	3	111	22499	2983542	1.256	0.488	2.776	1.806	1.053	1.806	0.305	1.09899023	0.22793207
Infliximab	Tinea versicolour	Tinea infections	Fungal infectious disorders	Infec	1968-2006	1	14	22501	2983639	1.194	0.276	3.739	6.249	4.198	6.249	0.04	0.83563334	0.17730901
Infliximab	Tinnitus	Inner ear signs and symptoms	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	29	12149	22473	2971504	0.341	0.25	0.457	0.335	38.251	0.334	6.22e-10	-1.6358419	-1.0758728
Infliximab	Tobacco user	Tobacco use	Lifestyle issues	SocCi	1968-2006	1	11	22501	2983642	1.156	0.267	3.618	5.403	3.091	5.403	0.079	0.86505951	0.14496577
Infliximab	Toe amputation	Limb therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	11	463	22491	2983190	1.317	0.793	2.085	1.462	1.535	1.462	0.215	1.38865497	0.27535642
Infliximab	Toe deformity	Extremity deformities	Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)	Musc	1968-2006	10	195	22492	2983458	2.15	1.262	3.473	2.776	10.536	2.777	0.001	2.10680192	0.76546784
Infliximab	Toe operation	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	13	22501	2983640	1.023	0.237	3.195	2.797	1.063	2.797	0.303	0.84537553	0.02273949
Infliximab	Tongue biting	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	2	265	22500	2983388	0.395	0.128	0.991	0.377	2.047	0.377	0.153	-0.0102831	-0.9288695
Infliximab	Tongue blistering	Tongue signs and symptoms	Tongue conditions	Gastr	1968-2006	1	155	22501	2983498	0.425	0.098	1.327	0.4	0.885	0.4	0.347	-0.1270848	-0.8556661
Infliximab	Tongue carcinoma stage IV	Lip and oral cavity neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	1	0	22501	2983653	1.397	0.317	4.467	1096.117	148.623	1103.825	3.467e-34	0.97840063	0.33432708
Infliximab	Tongue discolouration	Tongue signs and symptoms	Tongue conditions	Gastr	1968-2006	7	1764	22495	2981889	0.824	0.437	1.445	0.874	0.124	0.874	0.724	-0.845238	-0.1935847
Infliximab	Tongue disorder	Tongue disorders	Tongue conditions	Gastr	1968-2006	12	2364	22490	2981289	0.591	0.363	0.919	0.592	3.297	0.592	0.069	-0.5430589	-0.5259393
Infliximab	Tongue neoplasm malignant stage unspecified	Lip and oral cavity neoplasms malignant	Gastrointestinal neoplasms malignant and unspecified	Neopl	1968-2006	19	114	22483	2983539	5.649	3.787	8.339	9.499	116.38	9.505	3.924e-27	3.31424562	1.73147854
Infliximab	Tongue oedema	Tongue signs and symptoms	Tongue conditions	Gastr	1968-2006	24	6643	22478	2977010	0.778	0.552	1.072	0.787	1.367	0.786	0.242	-1.0399209	-0.2510288
Infliximab	Tongue paralysis	Hypoglossal nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	2	189	22500	2983464	0.676	0.219	1.694	0.765	0.142	0.765	0.706	0.29325706	-0.3915622
Infliximab	Tongue spasm	Tongue signs and symptoms	Tongue conditions	Gastr	1968-2006	1	63	22501	2983590	0.753	0.174	2.35	1.108	0.01	1.108	0.921	0.42444935	-0.2836901
Infliximab	Tongue ulceration	Tongue disorders	Tongue conditions	Gastr	1968-2006	4	398	22498	2983255	0.615	0.268	1.249	0.64	0.806	0.64	0.369	0.30762012	-0.486133
Infliximab	Tonsil cancer	Oropharyngeal, nasopharyngeal and tonsillar neoplasms malignant and unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	7	37	22495	2983616	3.865	2.024	6.979	9.377	44.384	9.382	2.699e-11	2.57841504	1.35196168
Infliximab	Tonsillectomy	Tonsillar therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	2	43	22500	2983610	1.383	0.448	3.471	3.003	2.416	3.003	0.12	1.15527573	0.32425505
Infliximab	Tonsillitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	13	347	22489	2983306	2.103	1.318	3.219	2.513	11.378	2.514	0.001	1.91088507	0.7433649
Infliximab	Tonsillitis streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	5	22501	2983648	1.264	0.292	3.972	15.243	8.328	15.243	0.004	0.92577585	0.2342813
Infliximab	Tooth abscess	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	18	820	22484	2982833	1.582	1.064	2.282	1.727	5.321	1.728	0.021	1.3742024	0.45868987
Infliximab	Tooth discolouration	Dental surface disorders	Dental and gingival conditions	Gastr	1968-2006	2	3525	22500	2980128	0.342	0.111	0.857	0.315	2.925	0.315	0.087	-3.2037214	-1.0729445
Infliximab	Tooth disorder	Dental disorders NEC	Dental and gingival conditions	Gastr	1968-2006	11	3438	22491	2980215	0.544	0.327	0.861	0.544	4.168	0.544	0.041	-1.1726062	-0.608806
Infliximab	Tooth erosion	Dental disorders NEC	Dental and gingival conditions	Gastr	1968-2006	1	55	22501	2983598	0.734	0.17	2.292	1.046	0.002	1.046	0.965	0.48407867	-0.3092463
Infliximab	Tooth extraction	Dental and gingival therapeutic procedures	Head and neck therapeutic procedures	Surg	1968-2006	4	1580	22498	2982073	0.213	0.093	0.433	0.196	13.104	0.196	0.0002946	-1.3741264	-1.5464631
Infliximab	Tooth fracture	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	171	22501	2983482	0.393	0.091	1.227	0.355	1.136	0.355	0.286	-0.2046768	-0.9339457
Infliximab	Tooth impacted	Dental disorders NEC	Dental and gingival conditions	Gastr	1968-2006	1	28	22501	2983625	0.902	0.209	2.815	1.788	0.322	1.788	0.571	0.70572945	-0.1031408
Infliximab	Tooth infection	Dental and oral soft tissue infections	Infections - pathogen class unspecified	Infec	1968-2006	6	313	22496	2983340	0.889	0.449	1.62	0.967	0.006	0.967	0.936	1.03600944	-0.117658
Infliximab	Tooth injury	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	197	22501	2983456	0.316	0.073	0.985	0.264	2.012	0.264	0.156	-0.3224906	-1.1520131
Infliximab	Tooth loss	Tooth missing	Dental and gingival conditions	Gastr	1968-2006	5	482	22497	2983171	0.603	0.286	1.152	0.619	1.157	0.619	0.282	0.35810436	-0.5058381
Infliximab	Toothache	Dental pain and sensation disorders	Dental and gingival conditions	Gastr	1968-2006	6	831	22496	2982822	0.482	0.243	0.878	0.478	3.351	0.478	0.067	-0.0648891	-0.7298112
Infliximab	Torsade de pointes	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	1	2521	22501	2981132	0.053	0.012	0.167	0.036	25.737	0.036	3.913e-7	-3.3251549	-2.9374634
Infliximab	Torulopsis infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	1	11	22501	2983642	1.076	0.249	3.363	3.602	1.639	3.602	0.201	0.86505951	0.07325046
Infliximab	Total lung capacity decreased	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	4	100	22498	2983553	1.803	0.787	3.665	3.034	5.01	3.034	0.025	1.480401	0.58945194
Infliximab	Toxic epidermal necrolysis	Bullous conditions	Epidermal and dermal conditions	Skin	1968-2006	7	4405	22495	2979248	0.21	0.111	0.368	0.199	22.555	0.199	2.042e-6	-2.101501	-1.5606477
Infliximab	Toxic induced encephalopathy	Encephalopathies toxic and metabolic	Encephalopathies	Nerv	1968-2006	2	147	22500	2983506	0.692	0.224	1.734	0.789	0.108	0.789	0.742	0.49318202	-0.3681693
Infliximab	Toxic shock syndrome	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	4	162	22498	2983491	1.189	0.519	2.416	1.514	0.67	1.514	0.413	1.14586241	0.17311262
Infliximab	Toxic shock syndrome streptococcal	Streptococcal infections	Bacterial infectious disorders	Infec	1968-2006	2	22	22500	2983631	1.634	0.529	4.11	5.379	5.858	5.379	0.016	1.33575551	0.491031
Infliximab	Toxic skin eruption	Dermatitis ascribed to specific agent	Epidermal and dermal conditions	Skin	1968-2006	21	1456	22481	2982197	0.936	0.648	1.316	0.96	0.035	0.96	0.852	0.85623254	-0.0661398
Infliximab	Toxicologic test abnormal	Toxicology laboratory analyses	Toxicology and therapeutic drug monitoring	Inv	1968-2006	1	1399	22501	2982254	0.063	0.014	0.199	0.044	21.188	0.044	4.163e-6	-2.5324945	-2.7646206
Infliximab	Toxoplasmosis	Toxoplasma infections	Protozoal infectious disorders	Infec	1968-2006	7	171	22495	2983482	2.013	1.067	3.528	2.78	7.507	2.781	0.006	1.76727088	0.69962615
Infliximab	Tracheal haemorrhage	Respiratory tract and thoracic cavity procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	30	22501	2983623	0.994	0.23	3.103	2.398	0.814	2.398	0.367	0.68809089	-0.0060181
Infliximab	Tracheal oedema	Tracheal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	42	22501	2983611	0.888	0.205	2.771	1.671	0.27	1.671	0.603	0.58656124	-0.1187835
Infliximab	Tracheal stenosis	Tracheal disorders (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	26	22501	2983627	0.912	0.211	2.846	1.851	0.362	1.851	0.548	0.72358631	-0.0921153
Infliximab	Tracheitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	3	61	22499	2983592	1.756	0.682	3.888	3.589	5.114	3.589	0.024	1.42444967	0.5630385
Infliximab	Tracheo-oesophageal fistula	Laryngeal and tracheal disorders congenital	Respiratory disorders congenital	Cong	1968-2006	1	63	22501	2983590	0.86	0.199	2.684	1.548	0.183	1.548	0.669	0.42444935	-0.1508229
Infliximab	Tracheobronchitis	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	3	86	22499	2983567	1.354	0.526	2.994	2.082	1.595	2.082	0.207	1.2525631	0.30306317
Infliximab	Transaminases increased	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	48	2948	22454	2980705	1.406	1.104	1.769	1.45	6.535	1.451	0.011	1.05240652	0.34074879
Infliximab	Transfusion	Blood and blood product treatment	Haematological and lymphoid tissue therapeutic procedures	Surg	1968-2006	2	13	22500	2983640	1.798	0.581	4.538	8.753	10.155	8.758	0.001	1.4205959	0.58667494
Infliximab	Transfusion reaction	Transfusion related complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	215	22500	2983438	0.593	0.192	1.487	0.634	0.409	0.634	0.522	0.18207994	-0.5225609
Infliximab	Transient acantholytic dermatosis	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	7	22501	2983646	1.293	0.298	4.07	15.468	11.536	15.468	0.001	0.90525186	0.2569651
Infliximab	Transient ischaemic attack	Transient cerebrovascular events	Central nervous system vascular disorders	Nerv	1968-2006	51	5856	22451	2977797	0.561	0.444	0.702	0.556	17.856	0.555	0.00002382	0.188014	-0.5780344
Infliximab	Transient tachypnoea of the newborn	Newborn respiratory disorders NEC	Neonatal respiratory disorders	Resp	1968-2006	2	82	22500	2983571	1.158	0.375	2.903	1.938	0.855	1.939	0.355	0.87030356	0.14669438
Infliximab	Transitional cell carcinoma	Urinary tract neoplasms malignant NEC	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	52	22501	2983601	0.809	0.187	2.525	1.316	0.072	1.316	0.788	0.50709068	-0.2119564
Infliximab	Transmission of drug via semen	Medication errors due to accidental exposures	Medication errors	Inj&P	1968-2006	15	455	22487	2983198	1.394	0.903	2.078	1.514	2.563	1.515	0.109	1.81322504	0.33217731
Infliximab	Transverse sinus thrombosis	Cerebrovascular venous and sinus thrombosis	Central nervous system vascular disorders	Nerv	1968-2006	1	62	22501	2983591	0.73	0.169	2.279	1.032	0.001	1.032	0.975	0.43176963	-0.3147107
Infliximab	Traumatic arthritis	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	9	22501	2983644	1.164	0.269	3.644	5.392	3.304	5.392	0.069	0.88501574	0.15186235
Infliximab	Traumatic brain injury	Cerebral injuries NEC	Injuries NEC	Inj&P	1968-2006	1	153	22501	2983500	0.463	0.107	1.447	0.453	0.638	0.453	0.425	-0.1170858	-0.7700282
Infliximab	Traumatic fracture	Fractures and dislocations NEC	Bone and joint injuries	Inj&P	1968-2006	3	51	22499	2983602	1.608	0.625	3.558	2.956	3.554	2.957	0.059	1.49937944	0.47499117
Infliximab	Treatment noncompliance	Medication errors NEC	Medication errors	Inj&P	1968-2006	30	4463	22472	2979190	0.364	0.268	0.486	0.358	34.489	0.356	4.287e-9	-0.1728147	-1.0106014
Infliximab	Tremor	Tremor (excl congenital)	Movement disorders (incl Parkinsonism)	Nerv	1968-2006	233	35775	22269	2947878	0.76	0.682	0.846	0.757	18.08	0.755	0.00002119	-0.237527	-0.2744368
Infliximab	Trichosporon infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	2	12	22500	2983641	1.922	0.619	4.881	10.529	15.528	10.541	0.0000813	1.43033808	0.65336631
Infliximab	Tricuspid valve disease	Tricuspid valvular disorders	Cardiac valve disorders	Card	1968-2006	2	109	22500	2983544	1.058	0.343	2.652	1.619	0.439	1.619	0.508	0.7015412	0.05638033
Infliximab	Tricuspid valve incompetence	Tricuspid valvular disorders	Cardiac valve disorders	Card	1968-2006	29	2454	22473	2981199	1.094	0.801	1.466	1.125	0.39	1.125	0.532	0.60311194	0.0898407
Infliximab	Tricuspid valve stenosis	Tricuspid valvular disorders	Cardiac valve disorders	Card	1968-2006	1	15	22501	2983638	1.262	0.291	3.964	11.681	8.094	11.681	0.004	0.82595649	0.23269776
Infliximab	Trigeminal nerve disorder	Trigeminal disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	2	51	22500	2983602	1.326	0.43	3.326	2.582	1.92	2.582	0.166	1.09205332	0.28216689
Infliximab	Trigeminal neuralgia	Trigeminal disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	2	235	22500	2983418	0.525	0.17	1.316	0.539	0.775	0.539	0.379	0.10203233	-0.644357
Infliximab	Trigger finger	Tendon disorders	Tendon, ligament and cartilage disorders	Musc	1968-2006	2	107	22500	2983546	0.879	0.285	2.204	1.151	0.038	1.151	0.845	0.71338725	-0.1289704
Infliximab	Triple vessel bypass graft				1968-2006	3	184	22499	2983469	0.802	0.312	1.773	0.919	0.021	0.919	0.884	0.72618562	-0.2206467
Infliximab	Trismus	Muscle tone abnormalities	Muscle disorders	Musc	1968-2006	38	1423	22464	2982230	3.692	2.812	4.778	4.415	90.403	4.42	1.943e-21	1.69662212	1.30616832
Infliximab	Trisomy 21	Autosomal chromosomal abnormalities	Chromosomal abnormalities and abnormal gene carriers	Cong	1968-2006	3	235	22499	2983418	0.715	0.278	1.58	0.787	0.17	0.786	0.68	0.51318199	-0.3354727
Infliximab	Troponin	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	3	32	22499	2983621	1.748	0.679	3.869	3.628	5.053	3.631	0.025	1.65344797	0.55847228
Infliximab	Troponin I	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	1	11	22501	2983642	1.056	0.244	3.301	3.171	1.399	3.172	0.237	0.86505951	0.05448819
Infliximab	Troponin I increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	5	179	22497	2983474	1.171	0.556	2.237	1.409	0.571	1.409	0.45	1.32471384	0.15785808
Infliximab	Troponin T increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	3	100	22499	2983553	1.22	0.474	2.696	1.737	0.883	1.737	0.347	1.16455805	0.19885086
Infliximab	Troponin increased	Skeletal and cardiac muscle analyses	Enzyme investigations NEC	Inv	1968-2006	6	524	22496	2983129	0.661	0.333	1.203	0.684	0.873	0.684	0.35	0.48382549	-0.4140014
Infliximab	Tubal ligation	Fallopian tube therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	26	22501	2983627	1.023	0.237	3.195	2.695	1.05	2.696	0.306	0.72358631	0.02273949
Infliximab	Tuberculin test negative	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	2	24	22500	2983629	1.922	0.619	4.879	12.627	15.429	12.627	0.00008567	1.31756088	0.65336631
Infliximab	Tuberculin test positive				1968-2006	43	196	22459	2983457	9.975	7.282	13.394	14.602	403.563	14.632	0	3.96874836	2.30008196
Infliximab	Tuberculoma of central nervous system	Nervous system infections NEC	Central nervous system infections and inflammations	Nerv	1968-2006	2	3	22500	2983650	2.09	0.665	5.411	19.351	29.57	19.351	5.394e-8	1.5211109	0.73716407
Infliximab	Tuberculosis	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	584	761	21918	2982892	24.653	23.02	26.377	53.687	13646.655	55.188	0	5.71277223	3.2048986
Infliximab	Tuberculosis gastrointestinal	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	25	16	22477	2983637	28.601	20.293	39.398	87.824	729.205	87.959	0	4.30343695	3.35344168
Infliximab	Tuberculosis liver	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	6	4	22496	2983649	16.45	3.661	43.86	106.427	176.256	106.611	3.184e-40	2.69237084	2.80032548
Infliximab	Tuberculosis of central nervous system	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	2	13	22500	2983640	1.922	0.619	4.88	11.225	15.622	11.226	0.00007735	1.4205959	0.65336631
Infliximab	Tuberculosis of genitourinary system	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	3	8	22499	2983645	2.779	1.047	6.571	24.643	38.921	24.643	4.413e-10	1.8750032	1.02209115
Infliximab	Tuberculosis of intrathoracic lymph nodes	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	1	0	22501	2983653	1.343	0.308	4.249	1074.85	50.194	1082.447	1.393e-12	0.97840063	0.29490592
Infliximab	Tuberculosis of peripheral lymph nodes	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	3	2	22499	2983651	3.672	1.183	23.769	174.08	90.549	174.08	1.805e-21	1.93614842	1.30073647
Infliximab	Tuberculosis skin test positive	Mycobacteria identification and serology	Microbiology and serology investigations	Inv	1968-2006	3	31	22499	2983622	1.723	0.669	3.813	3.539	4.78	3.542	0.029	1.66203108	0.54406696
Infliximab	Tuberculous pleurisy	Tuberculous infections	Mycobacterial infectious disorders	Infec	1968-2006	17	26	22485	2983627	15.708	8.827	24.108	33.164	273.665	33.197	0	3.75648817	2.75417014
Infliximab	Tubo-ovarian abscess	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	16	22501	2983637	1.087	0.251	3.396	3.634	1.769	3.634	0.184	0.81634411	0.08342161
Infliximab	Tubulointerstitial nephritis	Nephritis NEC	Nephropathies	Renal	1968-2006	1	176	22501	2983477	0.367	0.085	1.145	0.329	1.385	0.329	0.239	-0.2280928	-1.0023934
Infliximab	Tularaemia	Francisella infections	Bacterial infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.305	0.3	4.113	28.037	13.704	28.037	0.000214	0.95711984	0.26620304
Infliximab	Tumour excision	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	2	22	22500	2983631	1.58	0.511	3.969	4.459	4.876	4.459	0.027	1.33575551	0.45742485
Infliximab	Tumour lysis syndrome	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	1	639	22501	2983014	0.151	0.035	0.472	0.111	7.167	0.111	0.007	-1.5448599	-1.8904754
Infliximab	Tumour marker increased	Cell marker procedures	Immunology and allergy investigations	Inv	1968-2006	1	114	22501	2983539	0.44	0.102	1.373	0.425	0.784	0.425	0.376	0.0931742	-0.8209806
Infliximab	Tumour ulceration	Oncologic complications and emergencies	Cancer-related morbidities	Neopl	1968-2006	1	8	22501	2983645	1.217	0.281	3.814	7.274	5.187	7.274	0.023	0.89509832	0.19638881
Infliximab	Tunnel vision	Neurologic visual problems NEC	Neurological disorders of the eye	Nerv	1968-2006	1	181	22501	2983472	0.381	0.088	1.189	0.347	1.246	0.346	0.264	-0.251135	-0.9649559
Infliximab	Twin pregnancy	Multiple pregnancies	Pregnancy, labour, delivery and postpartum conditions	Preg	1968-2006	4	256	22498	2983397	0.821	0.358	1.668	0.913	0.033	0.913	0.857	0.75211903	-0.1972322
Infliximab	Tympanic membrane perforation	Tympanic membrane disorders (excl infections)	Middle ear disorders (excl congenital)	Ear	1968-2006	2	96	22500	2983557	0.921	0.298	2.308	1.247	0.094	1.247	0.76	0.7803382	-0.0822952
Infliximab	Type III immune complex mediated reaction	Allergic conditions NEC	Allergic conditions	Immun	1968-2006	57	4833	22445	2978820	11.026	8.478	14	16.732	571.933	16.873	0	0.61202113	2.40025612
Infliximab	Type IV hypersensitivity reaction	Allergic conditions NEC	Allergic conditions	Immun	1968-2006	57	175	22445	2983478	15.641	12.451	19.401	22.183	818.667	22.24	0	4.39466726	2.74989567
Infliximab	Typhoid fever	Salmonella infections	Bacterial infectious disorders	Infec	1968-2006	1	20	22501	2983633	1.075	0.249	3.36	3.336	1.611	3.336	0.204	0.77852244	0.07232066
Infliximab	Ulcer	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	29	2119	22473	2981534	0.759	0.556	1.017	0.764	2.089	0.764	0.148	0.80092184	-0.2757535
Infliximab	Ulcer haemorrhage	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	4	590	22498	2983063	0.416	0.182	0.845	0.405	3.437	0.405	0.064	-0.1344656	-0.87707
Infliximab	Ulcerative keratitis	Corneal infections, oedemas and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	10	606	22492	2983047	1.816	1.067	2.934	2.206	6.225	2.207	0.013	0.96005399	0.59663628
Infliximab	Ulna fracture	Upper limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	4	55	22498	2983598	2.11	0.92	4.295	4.178	8.793	4.18	0.003	1.78335646	0.74668795
Infliximab	Ulnar tunnel syndrome	Mononeuropathies	Peripheral neuropathies	Nerv	1968-2006	1	6	22501	2983647	1.207	0.279	3.782	7.792	4.768	7.795	0.029	0.91547736	0.18813794
Infliximab	Ultrasound Doppler abnormal	Vascular imaging procedures NEC	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	91	22501	2983562	0.614	0.142	1.917	0.73	0.097	0.73	0.755	0.23324737	-0.4877604
Infliximab	Ultrasound liver abnormal	Hepatobiliary imaging procedures	Hepatobiliary investigations	Inv	1968-2006	2	79	22500	2983574	1.239	0.401	3.107	2.244	1.304	2.244	0.253	0.89033393	0.2143046
Infliximab	Umbilical cord around neck	Umbilical cord complications	Neonatal and perinatal conditions	Preg	1968-2006	1	130	22501	2983523	0.412	0.095	1.287	0.381	0.984	0.381	0.321	0.00317803	-0.8867319
Infliximab	Umbilical hernia	Umbilical hernias	Abdominal hernias and other abdominal wall conditions	Gastr	1968-2006	7	258	22495	2983395	1.489	0.79	2.61	1.826	2.459	1.826	0.117	1.41197779	0.39810475
Infliximab	Umbilical hernia repair	Hernia repairs	Gastrointestinal therapeutic procedures	Surg	1968-2006	1	35	22501	2983618	1.021	0.236	3.188	2.724	1.033	2.724	0.309	0.64491541	0.02078254
Infliximab	Unevaluable event	General signs and symptoms NEC	General system disorders NEC	Genrl	1968-2006	46	17685	22456	2965968	0.649	0.507	0.821	0.647	8.754	0.646	0.003	-1.5279195	-0.4323226
Infliximab	Unintended pregnancy	Unintended pregnancies	Pregnancy, labour, delivery and postpartum conditions	Preg	1968-2006	1	12765	22501	2970888	0.028	0.006	0.089	0.019	51.398	0.019	7.543e-13	-5.6103395	-3.5755508
Infliximab	Unresponsive to pain stimuli				1968-2006	2	140	22500	2983513	0.756	0.245	1.894	0.902	0.02	0.902	0.886	0.5293716	-0.2797139
Infliximab	Unresponsive to stimuli	Neurological signs and symptoms NEC	Neurological disorders NEC	Nerv	1968-2006	1	105	22501	2983548	0.55	0.127	1.715	0.597	0.262	0.597	0.609	0.14637798	-0.597837
Infliximab	Unresponsive to verbal stimuli				1968-2006	2	210	22500	2983443	0.63	0.204	1.578	0.692	0.271	0.692	0.602	0.20280541	-0.4620355
Infliximab	Unwanted pregnancy	Unintended pregnancies	Pregnancy, labour, delivery and postpartum conditions	Preg	1968-2006	1	71	22501	2983582	0.793	0.183	2.475	1.249	0.048	1.249	0.826	0.36718681	-0.2319321
Infliximab	Upper gastrointestinal haemorrhage	Non-site specific gastrointestinal haemorrhages	Gastrointestinal haemorrhages NEC	Gastr	1968-2006	21	1835	22481	2981818	0.785	0.544	1.104	0.796	1.081	0.795	0.299	0.55116834	-0.2420716
Infliximab	Upper limb fracture	Upper limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	20	870	22482	2982783	1.228	0.843	1.741	1.294	1.289	1.294	0.256	1.44335004	0.20538683
Infliximab	Upper motor neurone lesion	Motor neurone diseases	Neuromuscular disorders	Nerv	1968-2006	1	59	22501	2983594	0.791	0.183	2.47	1.241	0.046	1.241	0.83	0.453956	-0.2344573
Infliximab	Upper respiratory fungal infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	4	6	22498	2983647	4.173	1.569	18.369	45.187	75.799	45.187	3.141e-18	2.20694394	1.4286352
Infliximab	Upper respiratory tract congestion	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	2	110	22500	2983543	0.854	0.277	2.14	1.095	0.016	1.095	0.899	0.69565445	-0.1578241
Infliximab	Upper respiratory tract infection	Upper respiratory tract infections	Infections - pathogen class unspecified	Infec	1968-2006	118	4642	22384	2979011	1.976	1.695	2.293	2.055	60.964	2.062	5.814e-15	1.68677503	0.6810746
Infliximab	Upper respiratory tract inflammation	Upper respiratory tract signs and symptoms	Respiratory disorders NEC	Resp	1968-2006	5	114	22497	2983539	1.638	0.777	3.129	2.28	3.438	2.28	0.064	1.65510691	0.49347599
Infliximab	Ureteral neoplasm	Urinary tract neoplasms unspecified malignancy NEC	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.268	0.292	3.985	16.448	8.768	16.448	0.003	0.946596	0.23744086
Infliximab	Ureteral stent insertion	Ureteric therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	1	15	22501	2983638	1.13	0.261	3.534	4.799	2.498	4.8	0.114	0.82595649	0.12221763
Infliximab	Ureteric cancer	Renal pelvis and ureter neoplasms malignant	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	14	22501	2983639	1.158	0.268	3.623	5.711	3.124	5.711	0.077	0.83563334	0.14669438
Infliximab	Ureteric dilatation	Ureteric disorders NEC	Ureteric disorders	Renal	1968-2006	1	62	22501	2983591	0.785	0.182	2.45	1.219	0.038	1.219	0.845	0.43176963	-0.2420716
Infliximab	Ureteric obstruction	Ureteric disorders NEC	Ureteric disorders	Renal	1968-2006	3	217	22499	2983436	0.831	0.323	1.837	0.965	0.004	0.965	0.951	0.58482384	-0.1851255
Infliximab	Ureteric operation	Ureteric therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	1	1	22501	2983652	1.348	0.309	4.267	99.995	26.967	99.995	2.07e-7	0.967721	0.29862201
Infliximab	Ureteric stenosis	Ureteric disorders NEC	Ureteric disorders	Renal	1968-2006	1	115	22501	2983538	0.577	0.134	1.802	0.655	0.18	0.655	0.671	0.08738197	-0.549913
Infliximab	Urethral cancer	Urinary tract neoplasms malignant NEC	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	1	10	22501	2983643	1.251	0.288	3.925	11.004	7.147	11.004	0.008	0.87500312	0.22394323
Infliximab	Urethral fistula	Structural and obstructive urethral disorders (excl congenital)	Urethral disorders (excl calculi)	Renal	1968-2006	2	8	22500	2983645	2.003	0.642	5.121	16.655	20.941	16.659	4.737e-6	1.46997828	0.69464606
Infliximab	Urethral intrinsic sphincter deficiency	Renal and urinary tract disorders congenital NEC	Renal and urinary tract disorders congenital	Cong	1968-2006	1	5	22501	2983648	1.299	0.299	4.092	23.823	12.544	23.823	0.0003976	0.92577585	0.26159474
Infliximab	Urethral meatus stenosis	Structural and obstructive urethral disorders (excl congenital)	Urethral disorders (excl calculi)	Renal	1968-2006	1	11	22501	2983642	1.234	0.285	3.869	9.339	6.051	9.344	0.014	0.86505951	0.21026093
Infliximab	Urethral polyp	Urethral neoplasms	Urethral disorders (excl calculi)	Renal	1968-2006	1	1	22501	2983652	1.355	0.31	4.293	103.07	30.75	103.07	2.935e-8	0.967721	0.30380145
Infliximab	Urethral stenosis	Structural and obstructive urethral disorders (excl congenital)	Urethral disorders (excl calculi)	Renal	1968-2006	1	81	22501	2983572	0.72	0.167	2.248	1.003	0	1.003	0.998	0.29866351	-0.3285041
Infliximab	Urethritis	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	3	302	22499	2983351	1.604	0.623	3.549	2.956	3.494	2.956	0.062	0.27399151	0.47250051
Infliximab	Urge incontinence	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	1	71	22501	2983582	0.675	0.156	2.105	0.874	0.018	0.874	0.895	0.36718681	-0.3930426
Infliximab	Urinary bladder abscess	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	2	3	22500	2983650	2.138	0.676	5.589	32.665	35.036	32.681	3.236e-9	1.5211109	0.75987081
Infliximab	Urinary bladder excision	Bladder therapeutic procedures	Renal and urinary tract therapeutic procedures	Surg	1968-2006	1	17	22501	2983636	1.226	0.283	3.844	7.577	5.613	7.578	0.018	0.80679534	0.20375684
Infliximab	Urinary bladder haemorrhage	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	7	159	22495	2983494	2.026	1.074	3.551	2.794	7.667	2.795	0.006	1.82393512	0.70606341
Infliximab	Urinary bladder polyp	Bladder neoplasms	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	1	27	22501	2983626	1.012	0.234	3.162	2.582	0.959	2.582	0.327	0.71463025	0.01192857
Infliximab	Urinary casts	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	2	266	22500	2983387	0.882	0.286	2.212	1.155	0.041	1.155	0.839	-0.0138805	-0.1255632
Infliximab	Urinary incontinence	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	39	8429	22463	2975224	0.653	0.499	0.842	0.652	7.151	0.651	0.007	-0.701658	-0.4261781
Infliximab	Urinary retention	Bladder and urethral symptoms	Urinary tract signs and symptoms	Renal	1968-2006	15	6969	22487	2976684	0.301	0.195	0.449	0.293	25.438	0.293	4.568e-7	-1.7496638	-1.200645
Infliximab	Urinary system x-ray abnormal	Urinary tract imaging procedures	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	5	22501	2983648	1.282	0.295	4.032	12.681	10.155	12.681	0.001	0.92577585	0.24842136
Infliximab	Urinary tract disorder	Genital and urinary tract disorders NEC	Genitourinary tract disorders NEC	Renal	1968-2006	4	1464	22498	2982189	0.486	0.212	0.988	0.486	2.152	0.486	0.142	-1.2731898	-0.7215467
Infliximab	Urinary tract infection	Urinary tract infections	Infections - pathogen class unspecified	Infec	1968-2006	271	12127	22231	2971526	1.801	1.629	1.988	1.85	101.879	1.864	5.901e-24	1.51918742	0.58834207
Infliximab	Urinary tract infection bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	72	22500	2983581	1.048	0.34	2.629	1.58	0.408	1.58	0.523	0.93818202	0.04688359
Infliximab	Urinary tract infection enterococcal	Enterococcal infections	Bacterial infectious disorders	Infec	1968-2006	7	172	22495	2983481	1.996	1.058	3.498	2.768	7.301	2.768	0.007	1.76264778	0.69114518
Infliximab	Urinary tract infection fungal	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	3	40	22499	2983613	1.867	0.725	4.134	4.117	6.573	4.118	0.01	1.58656148	0.62433286
Infliximab	Urinary tract infection pseudomonal	Pseudomonal infections	Bacterial infectious disorders	Infec	1968-2006	3	48	22499	2983605	1.964	0.762	4.355	4.664	8.053	4.664	0.005	1.52263875	0.67498321
Infliximab	Urinary tract infection staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	1	37	22501	2983616	0.91	0.211	2.842	1.83	0.354	1.83	0.552	0.62800058	-0.0943107
Infliximab	Urinary tract neoplasm	Urinary tract neoplasms unspecified malignancy NEC	Renal and urinary tract neoplasms malignant and unspecified	Neopl	1968-2006	2	3	22500	2983650	2.156	0.68	5.665	31.727	37.61	31.727	8.64e-10	1.5211109	0.76825465
Infliximab	Urinary tract obstruction	Genital and urinary tract disorders NEC	Genitourinary tract disorders NEC	Renal	1968-2006	1	283	22501	2983370	0.36	0.083	1.123	0.317	1.452	0.317	0.228	-0.6552141	-1.0216512
Infliximab	Urine abnormality	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	1	189	22501	2983464	0.325	0.075	1.016	0.276	1.871	0.276	0.171	-0.2872538	-1.1239301
Infliximab	Urine analysis abnormal	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	11	4369	22491	2979284	0.672	0.404	1.063	0.682	1.598	0.682	0.206	-1.5063289	-0.3974969
Infliximab	Urine ketone body present	Metabolism tests NEC	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	5	361	22497	2983292	0.878	0.416	1.676	0.969	0.005	0.969	0.944	0.67105568	-0.1301087
Infliximab	Urine leukocyte esterase positive	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	51	22501	2983602	0.724	0.167	2.259	1.013	0	1.013	0.99	0.51484364	-0.3229639
Infliximab	Urine odour abnormal	Urinary abnormalities	Urinary tract signs and symptoms	Renal	1968-2006	1	430	22501	2983223	0.207	0.048	0.648	0.157	4.45	0.157	0.035	-1.0903969	-1.5750365
Infliximab	Urine output decreased	Urinary tract function analyses NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	3	887	22499	2982766	0.213	0.083	0.471	0.193	10.166	0.193	0.001	-0.9489745	-1.5464631
Infliximab	Urine output increased	Urinary tract function analyses NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	134	22501	2983519	0.43	0.099	1.342	0.407	0.849	0.407	0.357	-0.0184705	-0.8439701
Infliximab	Urobilin urine present	Liver function analyses	Hepatobiliary investigations	Inv	1968-2006	1	50	22501	2983603	0.747	0.173	2.33	1.085	0.006	1.085	0.936	0.52263848	-0.2916901
Infliximab	Urogram abnormal	Urinary tract imaging procedures	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	13	22501	2983640	1.216	0.281	3.813	8.336	5.174	8.336	0.023	0.84537553	0.19556678
Infliximab	Urosepsis	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	56	543	22446	2983110	4.351	3.478	5.389	5.349	168.222	5.365	1.809e-38	3.36663427	1.4704057
Infliximab	Urticaria	Urticarias	Angioedema and urticaria	Skin	1968-2006	370	66927	22132	2916726	1.587	1.456	1.727	1.614	84.39	1.626	4.061e-20	-0.4876864	0.46184544
Infliximab	Urticaria chronic	Urticarias	Angioedema and urticaria	Skin	1968-2006	1	18	22501	2983635	0.999	0.231	3.12	2.567	0.863	2.567	0.353	0.79730935	-0.0010005
Infliximab	Urticaria generalised	Urticarias	Angioedema and urticaria	Skin	1968-2006	11	672	22491	2982981	0.865	0.52	1.369	0.9	0.118	0.9	0.731	0.96204357	-0.1450258
Infliximab	Urticaria papular	Urticarias	Angioedema and urticaria	Skin	1968-2006	1	115	22501	2983538	0.418	0.097	1.306	0.392	0.937	0.392	0.333	0.08738197	-0.8722738
Infliximab	Uterine atony	Uterine tone disorders	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	145	22501	2983508	0.752	0.174	2.347	1.103	0.009	1.103	0.923	-0.0763819	-0.285019
Infliximab	Uterine cancer	Uterine neoplasms malignant NEC	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	14	346	22488	2983307	1.892	1.206	2.856	2.207	8.696	2.208	0.003	2.0104211	0.63763447
Infliximab	Uterine contractions during pregnancy	Normal pregnancy, labour and delivery	Pregnancy, labour, delivery and postpartum conditions	Preg	1968-2006	1	89	22501	2983564	0.558	0.129	1.741	0.615	0.236	0.615	0.627	0.24609549	-0.5833963
Infliximab	Uterine dilation and curettage	Uterine therapeutic procedures	Obstetric and gynaecological therapeutic procedures	Surg	1968-2006	1	90	22501	2983563	0.59	0.136	1.84	0.675	0.15	0.675	0.698	0.23965713	-0.5276327
Infliximab	Uterine disorder	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	9	4736	22493	2978917	1.443	0.823	2.384	1.679	2.32	1.679	0.128	-1.8817298	0.36672428
Infliximab	Uterine enlargement	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	216	22501	2983437	0.526	0.122	1.643	0.558	0.343	0.558	0.558	-0.4028829	-0.6424541
Infliximab	Uterine haemorrhage	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	1323	22501	2982330	0.184	0.042	0.575	0.136	5.385	0.136	0.02	-2.4591301	-1.6928195
Infliximab	Uterine infection	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	28	22501	2983625	0.859	0.199	2.682	1.549	0.183	1.55	0.669	0.70572945	-0.1519864
Infliximab	Uterine leiomyoma	Uterine neoplasms benign	Reproductive neoplasms female benign	Neopl	1968-2006	17	1258	22485	2982395	1.084	0.721	1.58	1.136	0.266	1.136	0.606	0.76015863	0.0806579
Infliximab	Uterine leiomyosarcoma	Leiomyosarcomas	Soft tissue sarcomas	Neopl	1968-2006	1	6	22501	2983647	1.231	0.284	3.861	9.511	5.96	9.512	0.015	0.91547736	0.20782685
Infliximab	Uterine mass	Uterine disorders NEC	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	11	22501	2983642	1.133	0.262	3.544	4.888	2.57	4.888	0.109	0.86505951	0.12486898
Infliximab	Uterine neoplasm	Female reproductive neoplasms unspecified malignancy	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	3	141	22499	2983512	1.799	0.698	3.982	3.798	5.653	3.799	0.017	0.93397652	0.58723095
Infliximab	Uterine polyp	Uterine neoplasms	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	4	311	22498	2983342	0.659	0.288	1.339	0.692	0.532	0.692	0.466	0.56339096	-0.4170317
Infliximab	Uterine prolapse	Pelvic prolapse conditions	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	2	129	22500	2983524	0.736	0.239	1.845	0.867	0.04	0.867	0.842	0.58814077	-0.3065252
Infliximab	Uveitis	Iris and uveal tract infections, irritations and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	22	1083	22480	2982570	1.986	1.388	2.773	2.202	13.936	2.203	0.0001891	1.29943219	0.68612257
Infliximab	Uvulitis	Oral soft tissue disorders NEC	Oral soft tissue conditions	Gastr	1968-2006	1	6	22501	2983647	1.254	0.29	3.938	12.429	7.452	12.429	0.006	0.91547736	0.22633844
Infliximab	VIIth nerve paralysis	Facial cranial nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	1	33	22501	2983620	0.83	0.192	2.591	1.401	0.112	1.401	0.738	0.66203088	-0.1863296
Infliximab	VIth nerve paralysis	Eye movement disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	2	220	22500	2983433	0.63	0.204	1.58	0.69	0.269	0.69	0.604	0.16164792	-0.4620355
Infliximab	Vaccination complication	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	30	22501	2983623	0.955	0.221	2.983	2.117	0.571	2.117	0.45	0.68809089	-0.0460439
Infliximab	Vaginal abscess	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	9	22501	2983644	1.164	0.269	3.644	5.398	3.309	5.398	0.069	0.88501574	0.15186235
Infliximab	Vaginal cancer	Vaginal neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	5	32	22497	2983621	3.14	1.478	6.104	9.625	29.136	9.629	6.746e-8	2.22139614	1.1442228
Infliximab	Vaginal cancer recurrent	Vaginal neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	1	3	22501	2983650	1.345	0.308	4.255	104.544	25.432	104.544	4.582e-7	0.946596	0.29639401
Infliximab	Vaginal cancer stage 0	Vaginal neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	5	22500	2983648	2.101	0.668	5.447	35.361	30.658	35.372	3.077e-8	1.50043989	0.74241342
Infliximab	Vaginal candidiasis	Candida infections	Fungal infectious disorders	Infec	1968-2006	3	1522	22499	2982131	0.624	0.243	1.38	0.66	0.511	0.66	0.475	-1.6455982	-0.4716049
Infliximab	Vaginal cyst	Vulvovaginal cysts and neoplasms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	24	22501	2983629	1.019	0.236	3.182	2.743	1.019	2.743	0.313	0.74166694	0.01882175
Infliximab	Vaginal discharge	Vulvovaginal signs and symptoms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	6	4019	22496	2979634	0.275	0.139	0.502	0.261	12.385	0.26	0.0004327	-2.1655862	-1.2909842
Infliximab	Vaginal fistula	Vulvovaginal disorders NEC	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	2	4	22500	2983649	2.117	0.671	5.509	51.562	32.616	51.562	1.123e-8	1.51073838	0.74999999
Infliximab	Vaginal haemorrhage	Vulvovaginal disorders NEC	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	14	6788	22488	2976865	0.293	0.187	0.442	0.285	25.13	0.284	5.36e-7	-1.8053153	-1.2275827
Infliximab	Vaginal infection	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	6	9895	22496	2973758	0.48	0.242	0.874	0.475	3.397	0.475	0.065	-3.4392483	-0.7339692
Infliximab	Vaginal lesion	Vulvovaginal signs and symptoms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	20	22501	2983633	1.007	0.233	3.144	2.607	0.919	2.607	0.338	0.77852244	0.00697561
Infliximab	Vaginal prolapse	Pelvic prolapse conditions	Uterine, pelvic and broad ligament disorders	Repro	1968-2006	1	44	22501	2983609	0.83	0.192	2.591	1.405	0.112	1.405	0.738	0.5703131	-0.1863296
Infliximab	Vaginal ulceration	Vulvovaginal disorders NEC	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	2	60	22500	2983593	1.161	0.376	2.912	1.941	0.877	1.941	0.349	1.0240899	0.1492817
Infliximab	Vaginitis bacterial	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	2	99	22500	2983554	0.811	0.263	2.033	1.008	0	1.008	0.991	0.76176862	-0.2094872
Infliximab	Varicella	Herpes viral infections	Viral infectious disorders	Infec	1968-2006	12	187	22490	2983466	2.895	1.78	4.506	3.964	24.574	3.967	7.151e-7	2.37360765	1.06298511
Infliximab	Varices oesophageal	Oesophageal varices	Gastrointestinal vascular conditions	Gastr	1968-2006	10	487	22492	2983166	1.333	0.783	2.153	1.497	1.583	1.497	0.208	1.20950891	0.28743204
Infliximab	Varicose vein	Varicose veins non-site specific	Venous varices	Vasc	1968-2006	3	767	22499	2982886	0.488	0.19	1.079	0.487	1.584	0.487	0.208	-0.7690197	-0.7174399
Infliximab	Varicose vein operation	Venous therapeutic procedures	Vascular therapeutic procedures	Surg	1968-2006	1	51	22501	2983602	1.124	0.26	3.514	4.496	2.346	4.496	0.126	0.51484364	0.11689375
Infliximab	Vascular bypass graft	Vascular therapeutic procedures NEC	Vascular therapeutic procedures	Surg	1968-2006	3	182	22499	2983471	0.813	0.316	1.798	0.936	0.013	0.936	0.911	0.73521487	-0.2070242
Infliximab	Vascular calcification	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	6	130	22496	2983523	1.86	0.939	3.388	2.608	5.597	2.609	0.018	1.78352384	0.62057649
Infliximab	Vascular encephalopathy	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	21	22501	2983632	1.149	0.265	3.594	5.226	2.881	5.226	0.09	0.76921993	0.138892
Infliximab	Vascular graft occlusion	Cardiac and vascular procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	2	106	22500	2983547	0.824	0.267	2.067	1.035	0.002	1.035	0.961	0.71934695	-0.1935847
Infliximab	Vascular injury	Cardiovascular injuries	Injuries NEC	Inj&P	1968-2006	2	251	22500	2983402	0.515	0.167	1.29	0.528	0.844	0.528	0.358	0.04104508	-0.6635884
Infliximab	Vascular occlusion	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	5	377	22497	2983276	1.007	0.477	1.923	1.152	0.098	1.152	0.755	0.62556874	0.00697561
Infliximab	Vascular operation	Vascular therapeutic procedures NEC	Vascular therapeutic procedures	Surg	1968-2006	1	28	22501	2983625	0.901	0.208	2.813	1.774	0.319	1.774	0.572	0.70572945	-0.10425
Infliximab	Vascular pseudoaneurysm	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	3	180	22499	2983473	0.861	0.335	1.904	1.015	0.001	1.015	0.98	0.74430099	-0.1496608
Infliximab	Vascular purpura	Purpura and related conditions	Skin vascular abnormalities	Skin	1968-2006	1	572	22501	2983081	0.311	0.072	0.972	0.259	2.068	0.259	0.15	-1.4141327	-1.1679624
Infliximab	Vascular stenosis	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	38	22501	2983615	0.87	0.201	2.717	1.601	0.214	1.601	0.644	0.61961696	-0.1392621
Infliximab	Vasculitic rash	Skin vasculitides	Skin vascular abnormalities	Skin	1968-2006	8	162	22494	2983491	2.151	1.187	3.653	2.965	9.578	2.965	0.002	1.97472401	0.76593285
Infliximab	Vasculitis	Vasculitides NEC	Vascular inflammations	Vasc	1968-2006	151	5127	22351	2978526	4.019	3.51	4.585	4.459	367.227	4.485	0	1.89449048	1.39103312
Infliximab	Vasculitis cerebral	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	13	145	22489	2983508	3.534	2.213	5.422	5.236	39.885	5.24	2.694e-10	2.670343	1.26243037
Infliximab	Vasculitis gastrointestinal	Gastrointestinal disorders NEC	Gastrointestinal conditions NEC	Gastr	1968-2006	1	24	22501	2983629	0.987	0.228	3.083	2.415	0.771	2.415	0.38	0.74166694	-0.0130852
Infliximab	Vasculitis necrotising	Vasculitides NEC	Vascular inflammations	Vasc	1968-2006	11	197	22491	2983456	3.032	1.824	4.806	4.365	26.284	4.367	2.948e-7	2.21960549	1.10922247
Infliximab	Vasoconstriction	Peripheral vasoconstriction, necrosis and vascular insufficiency	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	209	22500	2983444	0.695	0.225	1.743	0.799	0.101	0.799	0.75	0.20698647	-0.3638434
Infliximab	Vasodilatation	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	12	23197	22490	2960456	0.585	0.359	0.909	0.585	3.437	0.585	0.064	-3.7706138	-0.5361434
Infliximab	Vasospasm	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	5	719	22497	2982934	0.821	0.389	1.569	0.894	0.063	0.894	0.802	-0.1086544	-0.1972322
Infliximab	Vein disorder	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	14	465	22488	2983188	1.749	1.115	2.64	2.002	6.638	2.003	0.01	1.6987582	0.5590442
Infliximab	Vein pain	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	82	22501	2983571	0.596	0.138	1.86	0.692	0.135	0.692	0.713	0.29198681	-0.5175146
Infliximab	Vena cava embolism	Vena caval embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	1	40	22501	2983613	0.946	0.219	2.954	2.093	0.522	2.093	0.47	0.60299444	-0.0555127
Infliximab	Vena cava thrombosis	Vena caval embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	2	190	22500	2983463	0.584	0.189	1.464	0.62	0.45	0.62	0.502	0.28881881	-0.5378543
Infliximab	Venoocclusive disease	Non-site specific vascular disorders NEC	Vascular disorders NEC	Vasc	1968-2006	1	187	22501	2983466	0.313	0.072	0.976	0.261	2.052	0.261	0.152	-0.2783085	-1.1615521
Infliximab	Venous angioma of brain	Venous disorders congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	13	22501	2983640	1.121	0.259	3.507	4.308	2.334	4.308	0.127	0.84537553	0.11422114
Infliximab	Venous insufficiency	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	1	133	22501	2983520	0.492	0.114	1.535	0.5	0.49	0.5	0.484	-0.0130888	-0.7092766
Infliximab	Venous occlusion	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	277	22500	2983376	0.542	0.176	1.358	0.561	0.67	0.561	0.413	-0.0528708	-0.6124893
Infliximab	Venous pressure jugular increased	Cardiac function diagnostic procedures	Cardiac and vascular investigations (excl enzyme tests)	Inv	1968-2006	1	166	22501	2983487	0.49	0.113	1.53	0.495	0.498	0.495	0.48	-0.1808744	-0.7133499
Infliximab	Venous stasis	Non-site specific necrosis and vascular insufficiency NEC	Arteriosclerosis, stenosis, vascular insufficiency and necrosis	Vasc	1968-2006	2	124	22500	2983529	0.894	0.29	2.241	1.184	0.055	1.184	0.814	0.61566636	-0.1120495
Infliximab	Venous thrombosis	Non-site specific embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	6	721	22496	2982932	0.546	0.276	0.995	0.549	2.176	0.549	0.14	0.108699	-0.6051363
Infliximab	Venous thrombosis limb	Peripheral embolism and thrombosis	Embolism and thrombosis	Vasc	1968-2006	6	236	22496	2983417	1.351	0.682	2.46	1.642	1.459	1.642	0.227	1.30508916	0.30084506
Infliximab	Ventilation/perfusion scan abnormal	Respiratory tract and thoracic imaging procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	1	63	22501	2983590	0.845	0.196	2.638	1.475	0.146	1.475	0.703	0.42444935	-0.1684187
Infliximab	Ventricle rupture	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	1	106	22501	2983547	0.75	0.173	2.341	1.096	0.008	1.096	0.928	0.14036864	-0.2876821
Infliximab	Ventricular arrhythmia	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	3	1389	22499	2982264	0.363	0.141	0.802	0.346	3.674	0.346	0.055	-1.5249442	-1.0133524
Infliximab	Ventricular dysfunction	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	24	977	22478	2982676	1.588	1.127	2.187	1.707	6.687	1.708	0.01	1.54630457	0.46247536
Infliximab	Ventricular dyskinesia	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	2	52	22500	2983601	1.27	0.412	3.186	2.386	1.508	2.386	0.219	1.0843418	0.2390169
Infliximab	Ventricular extrasystoles	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	44	5223	22458	2978430	0.995	0.773	1.264	1.009	0.003	1.009	0.954	0.14130634	-0.0050125
Infliximab	Ventricular failure	Heart failures NEC	Heart failures	Card	1968-2006	3	62	22499	2983591	1.527	0.593	3.377	2.601	2.829	2.601	0.093	1.41716634	0.42330503
Infliximab	Ventricular fibrillation	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	19	5820	22483	2977833	0.45	0.306	0.643	0.444	13.085	0.443	0.0002977	-1.1741471	-0.7985077
Infliximab	Ventricular flutter	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	1	78	22501	2983575	0.76	0.176	2.372	1.127	0.014	1.127	0.904	0.31888099	-0.2744368
Infliximab	Ventricular hypertrophy	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	38	2664	22464	2980989	1.034	0.788	1.338	1.054	0.101	1.054	0.751	0.86556094	0.03343478
Infliximab	Ventricular hypokinesia	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	21	691	22481	2982962	1.533	1.062	2.156	1.656	5.191	1.656	0.023	1.78615667	0.4272266
Infliximab	Ventricular septal defect	Cardiac septal defects congenital	Cardiac and vascular disorders congenital	Cong	1968-2006	1	661	22501	2982992	0.154	0.035	0.481	0.112	7.002	0.112	0.008	-1.5853263	-1.8708027
Infliximab	Ventricular septal defect acquired	Myocardial disorders NEC	Myocardial disorders	Card	1968-2006	2	23	22500	2983630	1.485	0.481	3.729	3.705	3.536	3.705	0.06	1.32662952	0.39541477
Infliximab	Ventricular tachycardia	Ventricular arrhythmias and cardiac arrest	Cardiac arrhythmias	Card	1968-2006	32	7594	22470	2976059	0.532	0.395	0.704	0.527	13.365	0.527	0.0002563	-0.8301643	-0.6311118
Infliximab	Ventriculoperitoneal shunt malfunction	Device malfunction events	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	1	6	22501	2983647	1.178	0.272	3.688	6.563	3.721	6.563	0.054	0.91547736	0.16381809
Infliximab	Verbally abused	Social issues	Lifestyle issues	SocCi	1968-2006	1	5	22501	2983648	1.268	0.292	3.985	14.522	8.664	14.522	0.003	0.92577585	0.23744086
Infliximab	Vertebral artery occlusion	Central nervous system haemorrhages and cerebrovascular accidents	Central nervous system vascular disorders	Nerv	1968-2006	1	40	22501	2983613	0.872	0.202	2.723	1.606	0.22	1.606	0.639	0.60299444	-0.1369659
Infliximab	Vertebral artery stenosis	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	43	22501	2983610	0.846	0.196	2.641	1.474	0.147	1.475	0.701	0.5784143	-0.1672359
Infliximab	Vertebral injury	Site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	1	53	22501	2983600	0.822	0.19	2.567	1.367	0.095	1.367	0.757	0.49937916	-0.1960149
Infliximab	Vertebrobasilar insufficiency	Central nervous system vascular disorders NEC	Central nervous system vascular disorders	Nerv	1968-2006	1	79	22501	2983574	0.72	0.167	2.247	1.001	0	1.001	0.999	0.31211031	-0.3285041
Infliximab	Vertigo	Inner ear signs and symptoms	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	82	10040	22420	2973613	0.843	0.701	1.007	0.845	2.302	0.844	0.129	0.09693663	-0.1707883
Infliximab	Vertigo labyrinthine	Inner ear signs and symptoms	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	1	5	22501	2983648	1.297	0.298	4.084	28.617	12.264	28.617	0.0004618	0.92577585	0.26005391
Infliximab	Vertigo positional	Inner ear signs and symptoms	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	5	176	22497	2983477	1.466	0.695	2.8	1.936	2.144	1.936	0.143	1.33840773	0.3825376
Infliximab	Vesical fistula	Bladder disorders NEC	Bladder and bladder neck disorders (excl calculi)	Renal	1968-2006	7	27	22495	2983626	4.519	2.297	9.124	13.826	63.595	13.832	1.528e-15	2.66203148	1.50829073
Infliximab	Vestibular disorder	Inner ear disorders NEC	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	5	791	22497	2982862	0.886	0.42	1.692	0.98	0.002	0.98	0.965	-0.224995	-0.1210383
Infliximab	Vestibular neuronitis	VIIIth cranial nerve disorders	Inner ear and VIIIth cranial nerve disorders	Ear	1968-2006	3	72	22499	2983581	1.548	0.601	3.423	2.67	3.001	2.671	0.083	1.34628634	0.43696378
Infliximab	Victim of crime	Crime victims	Legal issues	SocCi	1968-2006	1	106	22501	2983547	0.519	0.12	1.619	0.549	0.373	0.549	0.541	0.14036864	-0.6558514
Infliximab	Viraemia	Sepsis, bacteraemia and viraemia	Infections - pathogen class unspecified	Infec	1968-2006	1	121	22501	2983532	0.592	0.137	1.849	0.685	0.143	0.685	0.706	0.05310852	-0.5242486
Infliximab	Viral hepatitis carrier	Infectious disorders carrier	Ancillary infectious topics	Infec	1968-2006	1	20	22501	2983633	1.086	0.251	3.396	3.597	1.76	3.597	0.185	0.77852244	0.08250122
Infliximab	Viral infection	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	79	3554	22423	2980099	1.601	1.326	1.918	1.651	19.589	1.654	9.603e-6	1.49204614	0.47062843
Infliximab	Viral load increased	Virus identification and serology	Microbiology and serology investigations	Inv	1968-2006	1	178	22501	2983475	0.347	0.08	1.083	0.301	1.602	0.301	0.206	-0.2373539	-1.0584305
Infliximab	Viral myocarditis	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	4	107	22498	2983546	1.755	0.766	3.567	2.915	4.519	2.915	0.034	1.43850724	0.56246886
Infliximab	Viral pericarditis	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	3	55	22499	2983598	1.789	0.695	3.961	3.806	5.53	3.806	0.019	1.46893902	0.5816568
Infliximab	Viral pharyngitis	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	4	43	22498	2983610	2.421	1.055	4.944	5.864	14.164	5.866	0.0001675	1.87617438	0.88418068
Infliximab	Viral rash	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	1	51	22501	2983602	0.815	0.189	2.545	1.342	0.083	1.342	0.773	0.51484364	-0.2045672
Infliximab	Viral tracheitis	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	1	2	22501	2983651	1.301	0.299	4.098	18.913	12.952	18.913	0.0003195	0.95711984	0.2631332
Infliximab	Viral upper respiratory tract infection	Viral infections NEC	Viral infectious disorders	Infec	1968-2006	7	153	22495	2983500	2.099	1.113	3.68	3.02	8.522	3.021	0.004	1.85312412	0.74146104
Infliximab	Visceral leishmaniasis	Leishmania infections	Protozoal infectious disorders	Infec	1968-2006	2	23	22500	2983630	1.627	0.527	4.091	4.733	5.702	4.733	0.017	1.32662952	0.48673783
Infliximab	Vision blurred	Visual disorders NEC	Vision disorders	Eye	1968-2006	99	12678	22403	2970975	0.528	0.446	0.621	0.522	43.107	0.519	5.182e-11	0.03232868	-0.638659
Infliximab	Visual acuity reduced	Partial vision loss	Vision disorders	Eye	1968-2006	52	5689	22450	2977964	0.6	0.475	0.748	0.596	14.103	0.595	0.0001731	0.25577688	-0.5108256
Infliximab	Visual disturbance	Visual disorders NEC	Vision disorders	Eye	1968-2006	86	19615	22416	2964038	0.661	0.552	0.786	0.657	15.236	0.656	0.00009487	-0.7914198	-0.4140014
Infliximab	Visual evoked potentials abnormal	Neurologic diagnostic procedures	Neurological and special sense investigations	Inv	1968-2006	1	50	22501	2983603	0.821	0.19	2.562	1.358	0.093	1.358	0.761	0.52263848	-0.1972322
Infliximab	Visual field defect	Neurologic visual problems NEC	Neurological disorders of the eye	Nerv	1968-2006	21	2877	22481	2980776	0.901	0.624	1.267	0.922	0.137	0.922	0.712	-0.0569379	-0.10425
Infliximab	Vital capacity decreased	Respiratory and pulmonary function diagnostic procedures	Respiratory and pulmonary investigations (excl blood gases)	Inv	1968-2006	5	64	22497	2983589	2.896	1.368	5.581	6.965	22.394	6.966	0.00000222	1.97335801	1.06333047
Infliximab	Vitamin B complex deficiency	Water soluble vitamin deficiencies	Vitamin related disorders	Metab	1968-2006	2	27	22500	2983626	1.538	0.498	3.864	4.147	4.234	4.147	0.04	1.29069204	0.43048287
Infliximab	Vitamin B1 deficiency	Water soluble vitamin deficiencies	Vitamin related disorders	Metab	1968-2006	2	22	22500	2983631	1.726	0.558	4.347	6.259	7.925	6.26	0.005	1.33575551	0.54580659
Infliximab	Vitamin B12 decreased	Vitamin analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	106	22501	2983547	0.569	0.131	1.774	0.636	0.205	0.636	0.651	0.14036864	-0.5638748
Infliximab	Vitamin B12 deficiency	Water soluble vitamin deficiencies	Vitamin related disorders	Metab	1968-2006	1	248	22501	2983405	0.334	0.077	1.042	0.29	1.759	0.29	0.185	-0.5289109	-1.0966143
Infliximab	Vitamin B12 increased	Vitamin analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	54	22501	2983599	0.724	0.167	2.26	1.014	0	1.014	0.989	0.49170863	-0.3229639
Infliximab	Vitamin C deficiency	Water soluble vitamin deficiencies	Vitamin related disorders	Metab	1968-2006	1	11	22501	2983642	1.227	0.283	3.848	7.953	5.669	7.953	0.017	0.86505951	0.20457217
Infliximab	Vitamin D decreased	Vitamin analyses	Metabolic, nutritional and blood gas investigations	Inv	1968-2006	1	62	22501	2983591	0.665	0.154	2.075	0.849	0.026	0.849	0.872	0.43176963	-0.4079682
Infliximab	Vitamin K deficiency	Fat soluble vitamin deficiencies and disorders	Vitamin related disorders	Metab	1968-2006	2	93	22500	2983560	1.13	0.366	2.833	1.822	0.725	1.822	0.395	0.79914989	0.12221763
Infliximab	Vitiligo	Hypopigmentation disorders	Pigmentation disorders	Skin	1968-2006	8	692	22494	2982961	3.119	1.719	5.313	5.605	25.575	5.606	4.255e-7	0.51727076	1.13751244
Infliximab	Vitreous detachment	Choroid and vitreous structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	4	265	22498	2983388	0.893	0.39	1.815	1.018	0.001	1.018	0.971	0.71949735	-0.1131687
Infliximab	Vitreous disorder	Ocular disorders NEC	Eye disorders NEC	Eye	1968-2006	1	573	22501	2983080	0.478	0.111	1.493	0.48	0.557	0.48	0.456	-1.4161735	-0.7381445
Infliximab	Vitreous floaters	Choroid and vitreous structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	5	631	22497	2983022	0.483	0.229	0.922	0.479	2.776	0.479	0.096	0.04758513	-0.7277386
Infliximab	Vitreous haemorrhage	Choroid and vitreous haemorrhages and vascular disorders	Retina, choroid and vitreous haemorrhages and vascular disorders	Eye	1968-2006	4	327	22498	2983326	0.752	0.328	1.527	0.817	0.162	0.817	0.687	0.51282317	-0.285019
Infliximab	Vitreous opacities	Choroid and vitreous structural change, deposit and degeneration	Ocular structural change, deposit and degeneration NEC	Eye	1968-2006	1	83	22501	2983570	0.62	0.143	1.936	0.747	0.086	0.747	0.769	0.28534087	-0.4780358
Infliximab	Vitritis	Retinal, choroid and vitreous infections and inflammations	Ocular infections, irritations and inflammations	Eye	1968-2006	1	83	22501	2983570	0.583	0.135	1.82	0.662	0.166	0.662	0.683	0.28534087	-0.5395681
Infliximab	Vocal cord disorder	Laryngeal and adjacent sites disorders NEC (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	8	265	22494	2983388	1.706	0.942	2.896	2.13	4.497	2.13	0.034	1.55323042	0.53415145
Infliximab	Vocal cord neoplasm	Laryngeal neoplasms malignancy unspecified	Respiratory and mediastinal neoplasms malignant and unspecified	Neopl	1968-2006	3	8	22499	2983645	2.85	1.065	6.896	27.174	43.286	27.174	4.729e-11	1.8750032	1.04731899
Infliximab	Vocal cord paralysis	Vagus nerve disorders	Cranial nerve disorders (excl neoplasms)	Nerv	1968-2006	5	390	22497	2983263	1.1	0.522	2.101	1.294	0.323	1.294	0.57	0.58963798	0.09531018
Infliximab	Vocal cord thickening	Laryngeal and adjacent sites disorders NEC (excl infections and neoplasms)	Upper respiratory tract disorders (excl infections)	Resp	1968-2006	1	35	22501	2983618	0.925	0.214	2.889	1.928	0.418	1.928	0.518	0.64491541	-0.0779615
Infliximab	Volume blood decreased	Water and electrolyte analyses NEC	Water, electrolyte and mineral investigations	Inv	1968-2006	1	27	22501	2983626	0.955	0.221	2.983	2.104	0.574	2.104	0.449	0.71463025	-0.0460439
Infliximab	Volvulus	Large intestinal stenosis and obstruction	Gastrointestinal stenosis and obstruction	Gastr	1968-2006	1	156	22501	2983497	0.412	0.095	1.285	0.386	0.986	0.386	0.321	-0.1320585	-0.8867319
Infliximab	Vomiting	Nausea and vomiting symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	698	92791	21804	2890862	0.928	0.871	0.987	0.927	4.098	0.924	0.043	-0.0601168	-0.0747235
Infliximab	Vomiting projectile	Nausea and vomiting symptoms	Gastrointestinal signs and symptoms	Gastr	1968-2006	2	244	22500	2983409	0.508	0.165	1.274	0.519	0.891	0.519	0.345	0.06741043	-0.6772738
Infliximab	Vulval abscess	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	12	22501	2983641	1.117	0.258	3.494	4.324	2.273	4.324	0.132	0.85518395	0.11064652
Infliximab	Vulval cancer	Vulval neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	3	45	22499	2983608	1.679	0.652	3.715	3.314	4.269	3.314	0.039	1.54627915	0.51819838
Infliximab	Vulval cancer stage 0	Vulval neoplasms malignant	Reproductive neoplasms female malignant and unspecified	Neopl	1968-2006	2	1	22500	2983652	2.202	0.689	5.869	197.523	44.78	197.523	2.204e-11	1.54208236	0.78936604
Infliximab	Vulval cellulitis	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	3	22501	2983650	1.339	0.307	4.233	49.724	22.605	49.724	0.00000199	0.946596	0.29192307
Infliximab	Vulval disorder	Vulvovaginal disorders NEC	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	2	105	22500	2983548	0.854	0.277	2.141	1.097	0.017	1.097	0.897	0.72533136	-0.1578241
Infliximab	Vulval erythema	Vulvovaginal signs and symptoms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	19	22501	2983634	0.961	0.222	3	2.171	0.607	2.171	0.436	0.78788532	-0.0397809
Infliximab	Vulval oedema	Vulvovaginal signs and symptoms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	652	22501	2983001	0.109	0.025	0.342	0.076	11.082	0.076	0.001	-1.5689088	-2.2164074
Infliximab	Vulval ulceration	Vulvovaginal disorders NEC	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	40	22501	2983613	0.877	0.203	2.738	1.636	0.235	1.636	0.628	0.60299444	-0.1312483
Infliximab	Vulvovaginal discomfort	Vulvovaginal signs and symptoms	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	3348	22501	2980305	0.057	0.013	0.18	0.038	23.811	0.038	1.063e-6	-3.7166827	-2.864704
Infliximab	Vulvovaginal disorder	Vulvovaginal disorders NEC	Vulvovaginal disorders (excl infections and inflammations)	Repro	1968-2006	1	180	22501	2983473	0.818	0.189	2.552	1.34	0.087	1.341	0.768	-0.2465559	-0.2008929
Infliximab	Vulvovaginal mycotic infection	Fungal infections NEC	Fungal infectious disorders	Infec	1968-2006	6	391	22496	2983262	0.614	0.31	1.117	0.628	1.315	0.627	0.252	0.8065815	-0.4877604
Infliximab	Vulvovaginitis	Female reproductive tract infections	Infections - pathogen class unspecified	Infec	1968-2006	1	960	22501	2982693	0.494	0.114	1.542	0.506	0.479	0.506	0.489	-2.0457619	-0.7052198
Infliximab	Vulvovaginitis trichomonal	Trichomonas infections	Protozoal infectious disorders	Infec	1968-2006	1	12	22501	2983641	1.182	0.273	3.703	6.743	3.843	6.744	0.05	0.85518395	0.16720792
Infliximab	Waldenstroms macroglobulinaemia	Waldenstroms macroglobulinaemias	Lymphomas non-Hodgkins B-cell	Neopl	1968-2006	1	42	22501	2983611	0.846	0.196	2.64	1.477	0.147	1.477	0.701	0.58656124	-0.1672359
Infliximab	Walking aid user	Disability issues	Lifestyle issues	SocCi	1968-2006	1	255	22501	2983398	0.273	0.063	0.853	0.224	2.728	0.224	0.099	-0.5550714	-1.2982835
Infliximab	Walking disability	Disability issues	Lifestyle issues	SocCi	1968-2006	1	49	22501	2983604	0.722	0.167	2.254	1.008	0	1.008	0.994	0.53047566	-0.3257301
Infliximab	Wegeners granulomatosis	Lower respiratory tract inflammatory and immunologic conditions	Lower respiratory tract disorders (excl obstruction and infection)	Resp	1968-2006	4	142	22498	2983511	1.364	0.596	2.772	1.873	1.528	1.873	0.216	1.24554694	0.31042156
Infliximab	Weight decreased	Physical examination procedures	Physical examination topics	Inv	1968-2006	314	28791	22188	2954862	0.934	0.85	1.024	0.934	1.462	0.933	0.227	0.50051613	-0.0682788
Infliximab	Weight fluctuation	General nutritional disorders NEC	Appetite and general nutritional disorders	Metab	1968-2006	1	255	22501	2983398	0.26	0.06	0.812	0.206	3.002	0.206	0.083	-0.5550714	-1.3470736
Infliximab	Weight increased	Physical examination procedures	Physical examination topics	Inv	1968-2006	96	34631	22406	2949022	0.307	0.259	0.361	0.301	157.21	0.298	4.606e-36	-1.4553559	-1.1809075
Infliximab	West Nile viral infection	Flaviviral infections	Viral infectious disorders	Infec	1968-2006	5	48	22497	2983605	2.468	1.169	4.726	4.772	13.659	4.772	0.0002192	2.09205374	0.90340811
Infliximab	Wheelchair user	Disability issues	Lifestyle issues	SocCi	1968-2006	5	276	22497	2983377	1.089	0.516	2.079	1.277	0.289	1.277	0.591	0.94015286	0.08525984
Infliximab	Wheezing	Bronchospasm and obstruction	Bronchial disorders (excl neoplasms)	Resp	1968-2006	71	2652	22431	2981001	1.296	1.063	1.568	1.324	5.471	1.326	0.019	1.73944378	0.2592826
Infliximab	Whipples disease	Bacterial infections NEC	Bacterial infectious disorders	Infec	1968-2006	1	9	22501	2983644	1.244	0.287	3.903	9.023	6.679	9.023	0.01	0.88501574	0.21833199
Infliximab	White blood cell count	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	39	523	22463	2983130	2.521	1.927	3.252	2.812	42.415	2.834	7.38e-11	2.93045161	0.92465565
Infliximab	White blood cell count abnormal	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	13	494	22489	2983159	1.125	0.705	1.722	1.2	0.42	1.2	0.517	1.53472974	0.11778304
Infliximab	White blood cell count decreased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	107	9473	22395	2974180	0.718	0.611	0.839	0.715	12.051	0.714	0.001	0.55539352	-0.3312857
Infliximab	White blood cell count increased	White blood cell analyses	Haematology investigations (incl blood groups)	Inv	1968-2006	183	7139	22319	2976514	1.633	1.444	1.84	1.672	47.625	1.679	5.159e-12	1.70688066	0.49041881
Infliximab	White blood cell disorder	White blood cell abnormal findings NEC	White blood cell disorders	Blood	1968-2006	4	1009	22498	2982644	0.875	0.382	1.777	0.991	0	0.991	0.986	-0.7908164	-0.1335314
Infliximab	White blood cells stool positive	Faecal analyses NEC	Gastrointestinal investigations	Inv	1968-2006	1	22	22501	2983631	1.029	0.238	3.216	2.766	1.117	2.766	0.291	0.75997701	0.02858746
Infliximab	White blood cells urine	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	1	25	22501	2983628	0.917	0.212	2.864	1.888	0.386	1.888	0.534	0.7325983	-0.0866478
Infliximab	White blood cells urine positive	Urinalysis NEC	Renal and urinary tract investigations and urinalyses	Inv	1968-2006	13	604	22489	2983049	1.449	0.908	2.218	1.609	2.866	1.609	0.09	1.30605466	0.37087366
Infliximab	Whole blood transfusion				1968-2006	8	77	22494	2983576	3.338	1.838	5.699	6.444	30.371	6.446	3.569e-8	2.44865173	1.20537183
Infliximab	Wolff-Parkinson-White syndrome	Cardiac conduction disorders	Cardiac arrhythmias	Card	1968-2006	2	82	22500	2983571	1.135	0.368	2.847	1.844	0.747	1.844	0.388	0.87030356	0.12663265
Infliximab	Wound	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	14	420	22488	2983233	1.566	0.999	2.364	1.755	4.313	1.756	0.038	1.80885152	0.4485246
Infliximab	Wound debridement	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	3	412	22499	2983241	0.567	0.22	1.254	0.584	0.857	0.584	0.355	-0.0489136	-0.567396
Infliximab	Wound decomposition	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	3	10	22499	2983643	2.54	0.975	5.755	14.105	25.383	14.107	4.701e-7	1.85518405	0.93216408
Infliximab	Wound dehiscence	Non-site specific procedural complications	Procedural and device related injuries and complications NEC	Inj&P	1968-2006	17	437	22485	2983216	2.118	1.408	3.086	2.474	13.874	2.475	0.0001955	2.02191721	0.75047225
Infliximab	Wound drainage	Therapeutic procedures NEC	Therapeutic procedures and supportive care NEC	Surg	1968-2006	2	149	22500	2983504	0.649	0.21	1.627	0.719	0.212	0.719	0.645	0.48300669	-0.4323226
Infliximab	Wound haemorrhage	Haemorrhages NEC	Vascular haemorrhagic disorders	Vasc	1968-2006	3	134	22499	2983519	0.958	0.372	2.117	1.183	0.082	1.183	0.775	0.97082627	-0.0429075
Infliximab	Wound infection	Infections NEC	Infections - pathogen class unspecified	Infec	1968-2006	36	610	22466	2983043	3.185	2.408	4.149	3.7	65.098	3.704	7.127e-16	2.6534582	1.15845229
Infliximab	Wound infection staphylococcal	Staphylococcal infections	Bacterial infectious disorders	Infec	1968-2006	5	162	22497	2983491	1.348	0.639	2.574	1.709	1.417	1.709	0.234	1.40408914	0.29862201
Infliximab	Wound secretion	Non-site specific injuries NEC	Injuries NEC	Inj&P	1968-2006	8	443	22494	2983210	1.064	0.587	1.807	1.167	0.188	1.167	0.665	1.02929992	0.06203539
Infliximab	Wrist fracture	Upper limb fractures and dislocations	Bone and joint injuries	Inj&P	1968-2006	6	517	22496	2983136	0.682	0.344	1.242	0.707	0.712	0.707	0.399	0.49912812	-0.3827256
Infliximab	Wrist surgery	Joint therapeutic procedures	Bone and joint therapeutic procedures	Surg	1968-2006	1	19	22501	2983634	1.022	0.236	3.192	2.819	1.048	2.819	0.306	0.78788532	0.02176149
Infliximab	Wrong drug administered	Maladministrations	Medication errors	Inj&P	1968-2006	1	604	22501	2983049	0.155	0.036	0.485	0.115	6.907	0.114	0.009	-1.4780481	-1.8643302
Infliximab	X-ray	Imaging procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	1	1	22501	2983652	1.376	0.313	4.378	104.345	51.178	104.53	8.435e-13	0.967721	0.31918074
Infliximab	X-ray abnormal	Imaging procedures NEC	Investigations, imaging and histopathology procedures NEC	Inv	1968-2006	7	125	22495	2983528	2.555	1.354	4.483	4.139	14.917	4.139	0.0001124	1.99773681	0.93805222
Infliximab	X-ray gastrointestinal tract abnormal	Gastrointestinal and abdominal imaging procedures	Gastrointestinal investigations	Inv	1968-2006	1	75	22501	2983578	0.809	0.187	2.526	1.32	0.072	1.32	0.788	0.33938578	-0.2119564
Infliximab	X-ray limb abnormal	Musculoskeletal and soft tissue imaging procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	1	27	22501	2983626	0.971	0.225	3.031	2.273	0.664	2.273	0.415	0.71463025	-0.0294288
Infliximab	X-ray of pelvis and hip abnormal	Musculoskeletal and soft tissue imaging procedures	Musculoskeletal and soft tissue investigations (excl enzyme tests)	Inv	1968-2006	1	11	22501	2983642	1.144	0.264	3.579	5.207	2.812	5.207	0.094	0.86505951	0.13453089
Infliximab	Xanthoma	Skin neoplasms benign	Cutaneous neoplasms benign	Neopl	1968-2006	2	53	22500	2983600	1.563	0.506	3.928	4.218	4.59	4.219	0.032	1.07667128	0.44660705
Infliximab	Yellow skin	Dermal and epidermal conditions NEC	Epidermal and dermal conditions	Skin	1968-2006	1	312	22501	2983341	0.353	0.082	1.102	0.313	1.529	0.312	0.216	-0.7520908	-1.0412872
Infliximab	Yersinia infection	Yersinia infections	Bacterial infectious disorders	Infec	1968-2006	2	9	22500	2983644	1.907	0.614	4.836	10.805	14.772	10.807	0.0001213	1.45996566	0.64553133
Infliximab	hepatic failure SMQ (Custom Term)				1968-2006	397	40725	22105	2942928	0.838	0.771	0.909	0.835	12.91	0.832	0.0003268	0.3353785	-0.1767372
Infliximab	hepatitis SMQ (Custom Term)				1968-2006	151	21136	22351	2962517	0.823	0.719	0.939	0.822	5.74	0.821	0.017	-0.098156	-0.1947991
Infliximab	suicide SMQ (Custom Term)				1968-2006	62	45920	22440	2937733	0.126	0.102	0.154	0.122	408.91	0.119	0	-2.4871796	-2.0714734