"Runners are Far Ahead in Aging Healthfully" NY Times 10/12/94 The NY Times article seems to correspond well with the original study in the Annals of Internal Medicine. The major issue to get across, was that regular vigorous exercise helped maintain a healthy body and slow down some of the processes associated with aging. The article states that runners "were leaner, had fewer medical problems and fewer joint symptoms, took fewer medications and were less likely to have experienced previous disability that were the non-runners." At the beginning of the study, the runners (ever-runner and runner's club) seemed to be in better health than the non-runners. This points to one possible weakness in the research which is detailed in the Times article: "the initial health differences could reflect the fact that people in good shape initially are more likely to choose to be vigorously active." Like self-selection bias, this is a possible confounding variable, which skewed the results. The researchers also concede that "because this study was an observational comparison of self-selected groups without an externally imposed intervention, it could not determine whether the community controls could be made as healthy as the runners by instituting a more rigorous exercise program." This however, is endemic to many studies of this type; we find that there perhaps is a high correlation between health and a particular practice, but in this study, it would not be possible to have a longitudinal study of another 12 years or so, simply because of carry-over effects. One other issue that puzzled me was a discrepancy in the variables measured before and after. Initially, a whole array of physiological measures were tabulated, but the data at the end of the study reflects only a partial list of the initial criteria. Therefore, I was confused as to what measures were truly important, how and why they reduced the number of variables and what this could mean to their overall interpretation of the results. Overall, the findings are interesting, but not surprising. It has long been assumed that one's health is determined by nature, the environment and lifestyle. We are more able to alter lifestyle than the other components and thus a regular exercise regimen is prescribed for long, healthy lives. Performing another study, using an experimental format would not be feasible because of problems with confounding variables, and doing so would introduce some ethical concerns as they would be controlling behavior, forcing some people to run, others not to. Perhaps additional study could be performed measuring different types of vigorous activity, as alluded to in the journal article. Suggested Questions: 1. What kind of study was this? Observational? Experimental? Longitudinal? What are possible advantages and disadvantages to this type of study? 2. What were the largest differences between the two groups, and how did the study correct for these differences?