Answers: 1) "Panel finds no major risk from 'yo-yo' dieting", 20 Oct 94, NY Times, p. A10. 2) "Study on effects of yo-yo dieting is faulted", 26 Oct 94, NY Times, p. B12. Journal Article: "Weight cycling", National Task Force on the Prevention and Treatment of Obesity, 19 Oct 94, JAMA, v. 272, no. 15, pp. 1196-1202. 1. 43 studies were included in the meta-analysis. The researchers only chose studies that were published from 1966 to 1994, written in English, evaluated the effects of weight change or weight cycling on humans or animals in depth, and emphasized human subjects. (p.1196- "Methods") 2. The newspaper articles and the report were very explicit in stating the limitations of the studies used. They indicated that these studies failed to show aspects such as the effects due to intentional and nointentional weight loss and the differences in weight loss effects in obese people as opposed to those of normal weight. The report even called for more study on the psychological aspects of weight loss, while the article suggests for further research in the long-term health effects of yo-yo dieting. (p.1199-3rd pgrh, p.1201-"Conclusions", 10/26 article-7th and 10th pgrhs) 3a. Not all studies are in Tables 1 and 2 because there are several studies that did not define what weight cycling is and because some of the studies may not have concentrated on metabolic or psychologic effects or on mortality as an outcome. Not all the studies in Tables 1-2 are in Table 3 because of the previous reason (not focus on metabolic effects on weight cycling in humans). (Tables 1-3) b. If the studies are small, then one would more likely not find any significant effects because the confidence interval would be wide. Large studies, however, would more likely show yes effects because the confidence intervals are small to test the hypotheses. c. False. There are only two studies that could be considered large (classified as those with over 100 subjects) with "yes" effects, compared with around 4 smaller studies that are known. On the other hand, the smaller studies did tend to show "no" effects. (Table 1, Table 2, and References) d. Having many smaller studies in this meta-analysis do give a misleading picture of the situation because the sample sizes are very small to get results that are more likely on the average and are not outliers. 4. The newspaper articles are very good at explaining the limitations on such kind of analysis but are not explicit in the kinds of studies that were used (no description of the studies themselves in terms of sample sizes used, etc.) 5. 6.